D:Neuroaxonal Dystrophies

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Disease Term
Synonyms Adult Neuroaxonal Dystrophies, Adult Neuroaxonal Dystrophy, DISEASE SEITELBERGER S, Dystrophies Adult Neuroaxonal, DYSTROPHIES INFANTILE NEUROAXONAL, Dystrophies Juvenile Neuroaxonal, Dystrophies Neuroaxonal, Dystrophy Adult Neuroaxonal, Dystrophy Infantile Neuroaxonal, DYSTROPHY JUVENILE NEUROAXONAL, Dystrophy Neuroaxonal
Documents 7
Hot Single Events 2
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Neuroaxonal Dystrophies. They are ordered first by their relevance to Neuroaxonal Dystrophies and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT279889 Il6 Regulation of Socs3 1 0.21 0.17 0.05 5.00
2 INT279884 Nipbl Regulation of Transcription of Pcdhb1 1 0.25 0.05 0 5.00
3 INT279885 Ctcf Regulation of H19 1 0.12 0 0 5.00
4 INT279886 Shbdp1 Negative_regulation of Pcdhb1 1 0.10 0.09 0 5.00
5 INT279888 Binding of Rec8 and Nipbl 1 0.01 0.81 0 5.00
6 INT279890 Nipbl Regulation of Gene_expression of PCDHB@ 1 0.07 0.1 0 5.00
7 INT279891 Shbdp1 Negative_regulation of PCDHB@ 1 0.01 0.09 0 5.00
8 INT279892 Shbdp1 Negative_regulation of Gene_expression of PCDHB@ 1 0.01 0.09 0 5.00
9 INT320848 Binding of Npc1 and Npc2 1 0.39 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Neuroaxonal Dystrophies. They are ordered first by their pain relevance and then by number of times they were reported in Neuroaxonal Dystrophies. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 88.08
2 INT20233 Negative_regulation of SMPD1 8 0.51 4.19 1.4 81.84
3 INT279846 Gene_expression of Nipbl 1 0.68 11.1 0.56 79.56
4 INT4861 Localization of GRP 84 0.80 8.26 28.03 76.56
5 INT245157 Negative_regulation of Gene_expression of DMD 8 0.57 4.79 0.09 76.52
6 INT13396 Gene_expression of DMD 125 0.75 57.81 5.45 76.20
7 INT20232 Negative_regulation of Negative_regulation of SMPD1 1 0.37 0.55 0.1 71.92
8 INT3477 Regulation of Npc1 6 0.45 1.87 0.47 49.60
9 INT9055 Positive_regulation of Cog1 22 0.68 14.08 2.95 10.24
10 INT9054 Negative_regulation of Positive_regulation of Cog1 3 0.08 1.38 0.28 10.24
11 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
12 INT86521 Gene_expression of Lpar1 167 0.78 154.61 80.35 5.00
13 INT173693 Localization of Gopc 249 0.65 70.49 38.81 5.00
14 INT228870 Negative_regulation of Lpar1 17 0.51 20.97 8.77 5.00
15 INT78393 Gene_expression of Adm 16 0.78 8.4 4.92 5.00
16 INT111739 Negative_regulation of Npy 15 0.43 4.9 4.65 5.00
17 INT84430 Negative_regulation of Smpd1 22 0.59 10.33 3.95 5.00
18 INT94303 Gene_expression of Upf1 44 0.04 11.62 3.87 5.00
19 INT59837 Regulation of Upf1 5 0.03 1.37 1.45 5.00
20 INT103907 Negative_regulation of Upf1 15 0.37 4.3 1.4 5.00
21 INT135039 Gene_expression of Cd1 11 0.60 5.66 1.05 5.00
22 INT231266 Gene_expression of Prh1 13 0.08 3.95 1.02 5.00
23 INT116797 Gene_expression of Osmr 9 0.73 1.12 1 5.00
24 INT128609 Gene_expression of C1S 18 0.75 17.36 0.98 5.00
25 INT209387 Negative_regulation of Ugcg 9 0.25 7.61 0.9 5.00
26 INT95561 Negative_regulation of Vldlr 9 0.53 2.59 0.84 5.00
27 INT79941 Negative_regulation of Npc1 9 0.59 3.97 0.82 5.00
28 INT105344 Gene_expression of Cited2 5 0.78 3.65 0.76 5.00
29 INT42410 Positive_regulation of Cyb5d2 13 0.31 6.75 0.54 5.00
30 INT170346 Gene_expression of Npc1 18 0.78 7.69 0.48 5.00
31 INT225355 Gene_expression of Set 15 0.37 2.98 0.47 5.00
32 INT279847 Negative_regulation of Cebpb 2 0.28 1.82 0.44 5.00
33 INT238058 Negative_regulation of Shbdp1 4 0.10 1.36 0.42 5.00
34 INT97859 Localization of Npc1 12 0.75 6.66 0.35 5.00
35 INT4133 Binding of Npc1 14 0.47 8.24 0.33 5.00
36 INT32509 Positive_regulation of Npc1 6 0.50 2.24 0.33 5.00
37 INT84638 Regulation of Smpd1 3 0.37 2.36 0.22 5.00
38 INT138438 Gene_expression of Smpd1 7 0.67 2.67 0.21 5.00
39 INT181059 Gene_expression of Rnase1 5 0.25 0.98 0.19 5.00
40 INT279853 Negative_regulation of Gene_expression of Nipbl 1 0.51 2.37 0.19 5.00
41 INT240424 Binding of Ctsa 4 0.20 3.94 0.16 5.00
42 INT288084 Gene_expression of Rab9 2 0.27 1.05 0.13 5.00
43 INT143838 Gene_expression of Pitx2 3 0.53 1.86 0.09 5.00
44 INT279840 Positive_regulation of Gene_expression of Nipbl 1 0.44 0.22 0.07 5.00
45 INT320841 Positive_regulation of Chit1 1 0.02 0.82 0.07 5.00
46 INT320843 Negative_regulation of Gene_expression of Npc1 2 0.59 5.82 0.07 5.00
47 INT279851 Positive_regulation of Nipbl 1 0.44 0.19 0.04 5.00
48 INT279862 Binding of Nipbl 1 0.36 1.22 0.04 5.00
49 INT288082 Positive_regulation of Npc2 2 0.48 0.67 0.04 5.00
50 INT198787 Localization of Cyb5d2 3 0.73 0.56 0.03 5.00
51 INT244771 Gene_expression of Satb2 4 0.68 1.27 0.03 5.00
52 INT279854 Gene_expression of Ptx3 1 0.48 0.17 0.03 5.00
53 INT279869 Negative_regulation of Nipbl 1 0.43 4.3 0.03 5.00
54 INT319022 Positive_regulation of Binding of Npc1 2 0.50 0.24 0.03 5.00
55 INT320842 Localization of Npc2 1 0.76 1.01 0.03 5.00
56 INT279830 Regulation of Transcription of Nipbl 1 0.39 0.62 0 5.00
57 INT279831 Positive_regulation of Lias 1 0.01 0.26 0 5.00
58 INT279832 Gene_expression of Pcdhb1 1 0.72 0.06 0 5.00
59 INT279833 Transcription of Pcdhb1 1 0.67 0 0 5.00
60 INT279834 Negative_regulation of Pcdhb7 1 0.30 0.09 0 5.00
61 INT279835 Regulation of Transcription of Hbb-bh1 1 0.16 0 0 5.00
62 INT279837 Regulation of Gene_expression of Nipbl 1 0.39 0 0 5.00
63 INT279838 Protein_catabolism of Rec8 1 0.02 0.81 0 5.00
64 INT279839 Regulation of Transcription of Pcdhb1 1 0.42 0.05 0 5.00
65 INT279841 Transcription of Nipbl 1 0.63 1.21 0 5.00
66 INT279842 Regulation of Rec8 1 0.01 0.6 0 5.00
67 INT279843 Negative_regulation of Ebf1 1 0.37 0.6 0 5.00
68 INT279844 Localization of Pds5b 1 0.65 0.94 0 5.00
69 INT279845 Regulation of Nipbl 1 0.39 0.28 0 5.00
70 INT279849 Binding of Pds5b 1 0.32 0.93 0 5.00
71 INT279850 Gene_expression of Trps1 1 0.38 0.47 0 5.00
72 INT279855 Positive_regulation of Pcdhb1 1 0.47 0.08 0 5.00
73 INT279856 Regulation of Pcdhb1 1 0.42 0.89 0 5.00
74 INT279857 Localization of Nipbl 1 0.65 0 0 5.00
75 INT279858 Gene_expression of Tcof1 1 0.40 0.47 0 5.00
76 INT279859 Regulation of Pcdhb2 1 0.54 0 0 5.00
77 INT279860 Binding of Pcdhb7 1 0.26 0.09 0 5.00
78 INT279861 Positive_regulation of Gene_expression of Rnase1 1 0.15 0 0 5.00
79 INT279863 Localization of Pds5a 1 0.47 0.93 0 5.00
80 INT279864 Regulation of Ctcf 1 0.14 0.18 0 5.00
81 INT279865 Transcription of Ctcf 1 0.36 0 0 5.00
82 INT279866 Regulation of Stag1 1 0.38 0.09 0 5.00
83 INT279867 Binding of Rec8 1 0.01 0.81 0 5.00
84 INT279868 Positive_regulation of Positive_regulation of Pcdhb1 1 0.47 0.08 0 5.00
85 INT279870 Transcription of Hbb-bh1 1 0.25 0 0 5.00
86 INT279871 Negative_regulation of Transcription of Nipbl 1 0.43 1.22 0 5.00
87 INT279881 Negative_regulation of Gene_expression of PCDHB@ 1 0.05 0.09 0 5.00
88 INT279882 Regulation of PCDHB@ 1 0.06 0.89 0 5.00
89 INT279883 Gene_expression of PCDHB@ 1 0.10 0.19 0 5.00
90 INT288078 Gene_expression of Npc2 2 0.64 1.01 0 5.00
91 INT320839 Regulation of Gene_expression of Smpd1 1 0.37 0.61 0 5.00
92 INT320840 Binding of Npc2 1 0.46 1.81 0 5.00
93 INT320844 Regulation of Npc2 1 0.43 0 0 5.00
94 INT320845 Regulation of Localization of Npc1 1 0.39 0.71 0 5.00
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