D:Neuroblastoma

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Disease Term
Synonyms Neuroblastomas
Documents 1280
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Neuroblastoma. They are ordered first by their relevance to Neuroblastoma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT348637 Binding of TLE4 and OLFM1 1 0.01 1.67 0.24 100.00
2 INT6657 Binding of POMC and D15Mit108 1 0.03 0.49 0.37 100.00
3 INT302909 Nav2 Positive_regulation of Arhgef16 1 0.02 0.52 0 100.00
4 INT129291 Positive_regulation of OPRM1 Positive_regulation of Phosphorylation of RELA 1 0.06 0.27 0.28 100.00
5 INT88310 ITIH4 Positive_regulation of CXCR4 2 0.27 1.98 0.23 100.00
6 INT88311 ITIH4 Positive_regulation of CCR5 1 0.49 1.57 0.16 100.00
7 INT52711 BSG Regulation of ADCY1 1 0.01 0.1 0.12 100.00
8 INT34005 YY1 Regulation of KNG1 1 0.04 0.38 0.63 99.84
9 INT134114 Gnai2 Positive_regulation of Oprd1 Regulation of ADCY1 1 0.00 0.47 0.41 99.84
10 INT298998 Il18 Positive_regulation of Cdk5 1 0.11 0.36 0.17 99.72
11 INT299001 Il18 Positive_regulation of Cdk5r1 1 0.03 0.36 0.17 99.72
12 INT319786 Ccbp2 Positive_regulation of Negative_regulation of Dio1 1 0.09 0.94 0.05 99.70
13 INT182913 KCNIP3 Negative_regulation of PDYN 1 0.13 0.2 0.14 99.64
14 INT91454 MAPK1 Positive_regulation of Gene_expression of CPOX 1 0.20 0.6 0.1 99.60
15 INT129293 OPRM1 Positive_regulation of Phosphorylation of IKBKE 1 0.05 0.28 0.35 99.60
16 INT65985 IL1B Positive_regulation of Gene_expression of PTGS2 3 0.23 2.62 0.71 99.60
17 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5 99.52
18 INT79021 Regulation of Binding of Jun and Fos 2 0.50 0.66 1.5 99.52
19 INT121813 IL6 Positive_regulation of OPRM1 1 0.28 0.28 0.58 99.44
20 INT354822 Negative_regulation of Stat3 Negative_regulation of Positive_regulation of IFNA1 1 0.02 0.85 0.06 99.28
21 INT66339 LIF Positive_regulation of Phosphorylation of CLIP2 1 0.45 1.57 0 99.24
22 INT221955 Binding of ELAVL1 and CDK5R1 1 0.01 0.93 0.19 99.16
23 INT338894 TNFSF14 Negative_regulation of Gsk3a 1 0.00 0.54 1.04 99.12
24 INT122823 ERCC2 Regulation of Negative_regulation of OPRM1 1 0.23 0.17 0.63 99.10
25 INT182941 Gene_expression of KCNIP3 Positive_regulation of TNFRSF25 1 0.26 0.17 0 98.94
26 INT66342 LIF Positive_regulation of Phosphorylation of CLIP1 1 0.60 1.57 0 98.84
27 INT52114 Oprd1 Regulation of ADCY1 2 0.05 0.46 0.9 98.84
28 INT199499 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.8 0.86 98.80
29 INT199492 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.81 0.86 98.80
30 INT79602 Binding of PSMA5 and Oprd1 2 0.19 1.05 1.01 98.72
31 INT223471 Dok4 Regulation of Ret 1 0.30 0.17 0 98.72
32 INT211776 Binding of PTBP2 and PLVAP 1 0.05 0.43 0 98.54
33 INT142881 SGCG Positive_regulation of TRPV1 1 0.47 0.54 0.44 98.52
34 INT117008 Sfpi1 Regulation of Oprm1 1 0.56 0.56 1.49 98.52
35 INT117005 Sfpi1 Positive_regulation of Oprm1 1 0.52 0.56 0.94 98.52
36 INT277316 Upf1 Positive_regulation of Slc6a11 1 0.01 0.47 0.09 98.52
37 INT277320 Upf1 Positive_regulation of Upf1 Positive_regulation of Slc6a11 1 0.00 0.47 0.09 98.52
38 INT101715 PLAT Positive_regulation of NFKB1 2 0.11 0.99 1.09 98.44
39 INT88778 Binding of Oprm1 and Pomc 3 0.21 0.56 1.14 98.36
40 INT286045 Binding of Jun and Wwox 1 0.12 2.33 0.1 98.28
41 INT65986 IL1B Positive_regulation of PTGS2 3 0.32 2.05 1.03 98.28
42 INT238390 ELANE Positive_regulation of Gene_expression of TP53 1 0.04 0.42 0 98.24
43 INT117006 Sfpi1 Negative_regulation of Oprm1 1 0.39 0.29 0.49 98.24
44 INT44338 Binding of Penk and RGD1304827 1 0.02 0.2 0.38 98.12
45 INT44337 Penk Negative_regulation of RGD1304827 1 0.02 0.2 0.38 98.12
46 INT101719 PLAT Positive_regulation of NFYC 1 0.13 0.1 0.6 98.04
47 INT142882 IGF1 Positive_regulation of Gene_expression of TRPV1 1 0.06 0.57 0.52 97.96
48 INT65463 Bri3 Negative_regulation of Oprd1 1 0.10 0.39 0.94 97.96
49 INT334718 Binding of NOS1 and Bax 1 0.02 0.87 0 97.96
50 INT286046 Binding of Wwox and Creb1 1 0.14 1.67 0.1 97.88
51 INT182942 VDR Positive_regulation of CDKN1A 1 0.35 0.38 0 97.88
52 INT57217 ATF3 Positive_regulation of Gene_expression of PENK 1 0.24 0.18 0.16 97.72
53 INT199487 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.86 97.72
54 INT199500 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.85 97.72
55 INT57220 Positive_regulation of ATF3 Positive_regulation of PRKACA 1 0.17 0.1 0.09 97.72
56 INT57214 ATF3 Positive_regulation of PRKACA 1 0.17 0.1 0.09 97.72
57 INT142883 SGCG Positive_regulation of Gene_expression of TRPV1 1 0.32 0.27 0.21 97.60
58 INT199491 Il6 Positive_regulation of Positive_regulation of Il6 1 0.00 0.81 0.86 97.56
59 INT53052 ANTXRL Negative_regulation of Negative_regulation of ADCY1 1 0.01 0.66 0.99 97.36
60 INT65462 Bri3 Negative_regulation of Racgap1 1 0.02 0.39 0.93 97.30
61 INT72690 Binding of Hrh1 and Slc3a1 1 0.00 0.29 0.45 97.28
62 INT318473 Positive_regulation of OPRM1 Positive_regulation of CA2 1 0.17 0.46 2.13 97.12
63 INT182937 KCNIP3 Regulation of Binding of CA2 1 0.05 0.2 0.14 96.76
64 INT329121 Binding of LGI1 and ADAM22 1 0.14 0.5 0.06 96.64
65 INT258146 Binding of IGFBP3 and Hcrt 1 0.23 2.04 0 96.64
66 INT258086 Binding of CSF2 and IGFBP3 1 0.05 1.18 0 96.64
67 INT282708 Binding of MAPT and Y301C7L 1 0.00 0.54 0.16 96.60
68 INT106062 Positive_regulation of Oprl1 Positive_regulation of Mapk1 1 0.13 0.16 1.35 96.36
69 INT106071 Positive_regulation of Oprl1 Positive_regulation of MAPK3 1 0.12 0.16 1.34 96.36
70 INT329568 GOPC Positive_regulation of Phosphorylation of MAPK1 1 0.04 0.79 0 96.16
71 INT101717 PLAT Positive_regulation of JUND 1 0.17 0.1 0.59 95.72
72 INT86644 Binding of OPRD1 and DLL1 1 0.28 0.17 0.58 95.48
73 INT286028 Binding of Jun and Wwox 1 0.09 0.39 0 95.28
74 INT59687 Gene_expression of Opcml Regulation of Binding of Oprd1 1 0.00 0.54 0.62 95.16
75 INT238802 Binding of Ager and Renbp 6 0.02 6.46 0.22 95.04
76 INT182912 Binding of CDKN1A and FRA8E 1 0.02 0.37 0 94.84
77 INT308660 Binding of Ager and App 1 0.08 1.22 0.12 94.20
78 INT138195 Binding of HDAC4 and Creb1 1 0.03 0.17 0.13 94.08
79 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53 94.04
80 INT66344 ANTXR1 Positive_regulation of ART1 1 0.00 0.69 0 94.04
81 INT5416 Negative_regulation of Penk Positive_regulation of Pdia4 1 0.03 0.09 0.58 93.36
82 INT221961 Binding of ELAVL1 and UTS2R 1 0.00 0.26 0.03 93.28
83 INT93265 Binding of ADCY1 and OPRL1 1 0.13 0.17 0.51 93.20
84 INT165844 Binding of ATF4 and HSP90AB1 1 0.15 0.34 0.61 92.84
85 INT91457 IL1B Positive_regulation of Phosphorylation of MAPK1 1 0.40 0.47 0.12 92.56
86 INT91455 IL1B Positive_regulation of Phosphorylation of NFKB2 1 0.05 0.47 0.12 92.56
87 INT91458 IL1B Positive_regulation of Positive_regulation of NFKB2 1 0.08 0.47 0.12 92.56
88 INT134742 Binding of OPRM1 and SV2A 1 0.33 0.18 1.64 92.28
89 INT229499 Nde1 Regulation of Vim 1 0.00 0.35 0.04 92.16
90 INT89647 OPRM1 Regulation of ADCY1 1 0.09 0.09 0.47 91.84
91 INT55919 Binding of Sigmar1 and Ap2s1 1 0.02 0.84 0.6 91.44
92 INT243374 SERPINH1 Positive_regulation of Gene_expression of CAMK4 1 0.07 1.01 0 91.36
93 INT57213 Binding of TFAP2D and NSMCE2 1 0.01 0.09 0.08 91.24
94 INT153636 Binding of REST and Oprm1 1 0.02 0.09 0.09 91.20
95 INT298996 Il18 Positive_regulation of Gene_expression of Cdk5r1 1 0.03 1.65 0.29 91.12
96 INT299011 Il18 Positive_regulation of Transcription of Cdk5r1 1 0.03 1.65 0.29 91.12
97 INT257218 Camk1 Negative_regulation of Nos1 1 0.04 0.09 0.19 91.08
98 INT103592 CAP1 Negative_regulation of Gene_expression of CPOX 1 0.19 1.52 1.64 91.04
99 INT88777 Positive_regulation of Binding of Oprm1 and Pomc 1 0.16 0.09 0.24 90.96
100 INT237921 ROS1 Positive_regulation of TNFRSF10B 1 0.08 1.24 0.03 90.96
101 INT298995 Il18 Positive_regulation of Gene_expression of Cdk5 1 0.12 1.65 0.29 90.80
102 INT299008 Il18 Positive_regulation of Transcription of Cdk5 1 0.12 1.65 0.29 90.80
103 INT94262 IL1B Positive_regulation of Localization of PTGER2 1 0.22 0.8 0.49 90.76
104 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86 90.68
105 INT308659 Binding of Ager and ecs 1 0.01 1.14 0.12 90.64
106 INT106070 Positive_regulation of Oprl1 Positive_regulation of TH 1 0.13 0.15 1.36 90.52
107 INT201380 RARA Positive_regulation of Regulation of CPOX 1 0.07 0.21 0.08 90.40
108 INT229500 Binding of Vim and Nde1 1 0.00 0.79 0.07 90.32
109 INT72849 RT1-EC2 Positive_regulation of Adrbk1 1 0.01 0.33 0.1 90.24
110 INT72848 RT1-EC2 Positive_regulation of Adrbk2 1 0.00 0.33 0.1 90.24
111 INT72847 Adrbk2 Positive_regulation of Adrbk1 1 0.02 0.33 0.1 90.24
112 INT182935 KCNIP3 Regulation of CDKN1A 1 0.45 0.96 0 90.16
113 INT355815 BACE1 Regulation of Positive_regulation of NAV1 1 0.32 0.26 0.72 90.00
114 INT175074 Binding of Fn1 and Psmc1 1 0.02 0.34 0 89.72
115 INT77924 Binding of SCD and Oprd1 1 0.00 0.25 0.4 89.48
116 INT77923 Negative_regulation of Binding of SCD and Oprd1 1 0.00 0.25 0.4 89.48
117 INT223477 Binding of Ntrk1 and Ntrk3 2 0.16 0.3 0.19 89.44
118 INT223475 Binding of Ntrk1 and Ntrk2 2 0.22 0.25 0.14 89.44
119 INT223478 Binding of Ntrk1 and Dok5 1 0.18 0.17 0 89.44
120 INT5417 Penk Positive_regulation of Pdia4 1 0.03 0.09 0.52 89.20
121 INT142885 Positive_regulation of IGF1 Positive_regulation of TRPV1 1 0.04 0.24 0.29 89.08
122 INT74600 Negative_regulation of YY1 Negative_regulation of ADCY1 1 0.36 0.25 0.17 88.88
123 INT221960 Binding of C4B and ELAVL1 1 0.00 0.15 0 88.80
124 INT74599 YY1 Negative_regulation of ADCY1 2 0.36 0.31 0.67 88.56
125 INT133481 TNF Positive_regulation of Phosphorylation of PTEN 1 0.13 0.61 0.09 88.52
126 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57 88.40
127 INT264864 Cd38 Positive_regulation of Localization of INS 1 0.06 0.51 0 88.40
128 INT52383 Binding of Gs and Ptprg 1 0.00 0.48 0.44 88.36
129 INT142884 IGF1 Positive_regulation of TRPV1 1 0.04 0.24 0.28 88.36
130 INT106558 Binding of Ntrk2 and Ntrk3 3 0.52 2.51 2.28 88.32
131 INT223472 Binding of Dok5 and Rbm39 1 0.01 0.17 0 88.32
132 INT238395 BAX Regulation of CDKN1A 1 0.03 0.31 0.03 88.24
133 INT175075 Binding of Ptn and Klk1c9 1 0.03 0.41 0 88.16
134 INT337697 FGF2 Regulation of VEGFA 1 0.03 0.51 0.18 87.92
135 INT337698 VEGFA Regulation of FGFR1 1 0.09 0.51 0.18 87.92
136 INT201212 FGF2 Regulation of FGFR1 2 0.09 1.01 0.18 87.56
137 INT223476 Binding of Ntrk3 and Dok5 1 0.20 0.17 0 87.52
138 INT106397 Positive_regulation of OPRL1 Positive_regulation of ADRBK1 1 0.46 0.09 0.31 87.40
139 INT217150 MIR16-2 Regulation of BCL2 2 0.09 1.89 0 87.32
140 INT217137 MIR15B Regulation of BCL2 2 0.15 1.88 0 87.32
141 INT313305 SQSTM1 Regulation of NFE2L2 1 0.35 0.09 0 87.24
142 INT313292 Positive_regulation of SQSTM1 Regulation of NFE2L2 1 0.26 0.09 0 87.24
143 INT211777 Binding of NTSR1 and PTBP1 1 0.03 0.82 0 87.20
144 INT119319 Binding of Atrn and Rhox3h 1 0.00 0.3 0.37 87.20
145 INT211781 Binding of NTSR1 and RDBP 1 0.00 0.42 0 87.20
146 INT223479 Binding of Ntrk2 and Dok5 1 0.26 0.17 0 86.80
147 INT57219 Binding of ATF3 and JUND 1 0.31 0.39 0.38 86.32
148 INT57221 Binding of ATF3 and PENK 1 0.17 0.26 0.24 86.32
149 INT60194 Binding of CCK and FOS 1 0.36 0.09 0.25 86.32
150 INT60195 Binding of CCK and JUN 1 0.39 0.09 0.25 86.16
151 INT108197 AKT1 Regulation of JUN 1 0.29 0.25 0.4 86.08
152 INT319787 Binding of Dio1 and Ccbp2 1 0.06 0.92 0.03 86.00
153 INT182964 KCNIP3 Regulation of Gene_expression of TNFRSF25 1 0.19 0.31 0 85.76
154 INT114244 Cpox Negative_regulation of Gene_expression of APP 1 0.00 0.7 0.25 85.64
155 INT172716 Binding of BCL3 and NFKB1 1 0.06 0.15 0.03 85.52
156 INT229497 Binding of Vim and Ndel1 1 0.33 3.5 2.81 85.52
157 INT66341 LIF Positive_regulation of Gene_expression of FOS 1 0.11 1.07 0 85.24
158 INT34006 Binding of ITPR3 and YY1 1 0.22 0.33 0.48 85.24
159 INT182911 KCNIP3 Positive_regulation of CDKN1A 1 0.51 0.35 0 85.16
160 INT355814 BACE1 Regulation of Gene_expression of NAV1 1 0.37 0.24 0.72 84.88
161 INT182951 Binding of CA2 and Positive_regulation of Localization of KCNIP3 1 0.09 0.17 0.12 84.80
162 INT250588 Binding of BSG and MCTS1 1 0.11 1.83 0 84.20
163 INT250591 Binding of BSG and MCTS1 Regulation of MCTS1 1 0.06 0.5 0 84.20
164 INT238400 Binding of SRA1 and Positive_regulation of Negative_regulation of MAX 1 0.03 0.43 0 83.76
165 INT238389 SRA1 Positive_regulation of Negative_regulation of MAX 1 0.03 0.43 0 83.76
166 INT69178 Binding of SLC3A2 and Adarb1 1 0.00 0.16 0.53 83.76
167 INT241072 Tpr Positive_regulation of Regulation of Oprm1 1 0.01 0.08 0.36 83.76
168 INT308647 Ager Positive_regulation of Gene_expression of Bace1 1 0.09 1.01 0.12 83.76
169 INT72689 Binding of Oprd1 and Ptprg 1 0.00 0.38 0.71 83.52
170 INT87267 Binding of BMP8B and KRIT1 1 0.06 0.16 2.69 83.40
171 INT175076 Binding of Fgf2 and Klk1c9 1 0.02 0.38 0 83.28
172 INT80877 Negative_regulation of PCDHB17 Negative_regulation of ADCY1 1 0.01 0.08 0.84 83.28
173 INT80878 PCDHB17 Negative_regulation of ADCY1 1 0.01 0.08 0.84 83.28
174 INT229508 Binding of Fez1 and Disc1 1 0.03 0.34 0.03 83.28
175 INT229503 Binding of Ndel1 and Fez1 1 0.15 0.34 0.03 83.28
176 INT57218 Binding of JUND and PENK 1 0.11 0.16 0.15 83.24
177 INT76165 IGKV2-30 Positive_regulation of Phosphorylation of Oprm1 1 0.00 0.08 1.22 83.24
178 INT310229 Binding of INS and SUCLA2 1 0.07 4.69 0 82.88
179 INT87274 CALM1 Regulation of Oprd1 1 0.01 0.08 0.72 82.80
180 INT87275 KRIT1 Regulation of Oprd1 1 0.01 0.08 0.72 82.80
181 INT69179 Binding of UBA7 and Adarb1 1 0.00 0.16 0.53 82.76
182 INT267258 Binding of TP53 and BCL11B 1 0.09 0.42 0 82.72
183 INT229493 Binding of Ndel1 and Disc1 1 0.13 0.68 0.06 82.48
184 INT153637 Gene_expression of REST Positive_regulation of Gene_expression of Oprm1 1 0.03 0.08 0.1 82.48
185 INT76163 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.02 0.08 1.22 82.20
186 INT310230 INS Negative_regulation of Localization of SUCLA2 1 0.07 1.09 0 82.08
187 INT243373 Binding of CASP8 and SERPINH1 1 0.28 1.49 0 82.04
188 INT131949 ANTXR1 Positive_regulation of NAV1 1 0.03 0.23 1.38 81.84
189 INT241070 Klf16 Positive_regulation of Drd1a 1 0.05 0.13 0.12 81.76
190 INT241075 Klf16 Negative_regulation of Tpr 1 0.00 0.13 0.12 81.76
191 INT241073 Klf16 Positive_regulation of Tpr 1 0.01 0.13 0.12 81.76
192 INT310241 INS Positive_regulation of Akt1 1 0.30 0.98 0 81.60
193 INT310240 INS Positive_regulation of Trib3 1 0.00 0.98 0 81.60
194 INT66340 LIF Positive_regulation of C1orf61 1 0.12 0.52 0 81.48
195 INT76458 Binding of Oprd1 and Coq10a 1 0.01 0.08 0.6 81.44
196 INT237979 PPARA Negative_regulation of Birc5 1 0.49 1.26 0 81.40
197 INT280843 Binding of Crem and Crh 1 0.03 0.22 0.04 81.28
198 INT166590 Binding of RAMP1 and DCLK3 2 0.37 0.39 4.8 81.12
199 INT56859 Oprd1 Positive_regulation of OPRD1 1 0.01 0.22 0.61 80.88
200 INT184114 Tlr4 Positive_regulation of Socs3 2 0.65 1.14 0.83 80.88

Single Events

The table below shows the top 200 pain related interactions that have been reported for Neuroblastoma. They are ordered first by their pain relevance and then by number of times they were reported in Neuroblastoma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT240173 Gene_expression of Chd5 1 0.74 42.06 0.42 100.00
2 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4 100.00
3 INT96764 Positive_regulation of Gene_expression of SOD1 36 0.61 16.55 1.99 100.00
4 INT32718 Gene_expression of OPRD1 82 0.76 9.43 48.38 100.00
5 INT26058 Gene_expression of SH3BP5 12 0.23 2.81 4.88 100.00
6 INT65731 Gene_expression of Cnr1 234 0.78 63.82 109.34 100.00
7 INT26063 Regulation of SH3BP5 2 0.45 1.99 0.92 100.00
8 INT26061 Positive_regulation of Gene_expression of SH3BP5 2 0.13 1.28 1.25 100.00
9 INT12617 Regulation of ADCY1 41 0.61 7.38 15.94 100.00
10 INT220729 Positive_regulation of Gene_expression of ETF1 1 0.01 0.82 0.2 100.00
11 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85 100.00
12 INT240169 Transcription of Tusc1 1 0.04 1.12 0 100.00
13 INT30080 Binding of Arhgef16 1 0.11 0.54 0.45 100.00
14 INT101763 Localization of Nbl1 1 0.26 0.86 0.46 100.00
15 INT101764 Gene_expression of Nbl1 1 0.27 0.84 0.44 100.00
16 INT3593 Gene_expression of ADRA1D 70 0.75 29.48 20.87 100.00
17 INT117427 Gene_expression of Parn 1 0.44 1.18 0.79 100.00
18 INT26062 Positive_regulation of Regulation of SH3BP5 1 0.04 0.75 0.09 100.00
19 INT49882 Positive_regulation of NPBWR1 5 0.67 0.89 1.56 100.00
20 INT6601 Gene_expression of PPAP2A 21 0.27 3.13 5.52 100.00
21 INT348639 Gene_expression of OLFM1 1 0.12 1.57 0.19 100.00
22 INT34037 Regulation of Arhgef16 1 0.15 0.6 0.45 100.00
23 INT348638 Binding of OLFM1 1 0.07 1.09 0.21 100.00
24 INT104310 Gene_expression of NPFFR1 7 0.75 1.03 3.94 100.00
25 INT13908 Gene_expression of PHOX2B 1 0.25 0.6 0.09 100.00
26 INT167858 Regulation of Gene_expression of Mat1a 3 0.61 2.97 2.33 100.00
27 INT18930 Positive_regulation of Hrh1 20 0.63 7.77 12.96 100.00
28 INT57057 Gene_expression of APC 131 0.78 122.24 8.7 100.00
29 INT57066 Gene_expression of GORAB 1 0.08 0.27 0.11 100.00
30 INT57061 Gene_expression of GNAZ 2 0.38 0.93 0.11 100.00
31 INT7717 Positive_regulation of Adra2a 62 0.70 17.68 27.32 100.00
32 INT4465 Gene_expression of CEL 116 0.77 98.35 23.58 100.00
33 INT57253 Negative_regulation of Binding of Oprm1 24 0.43 5.27 22.67 100.00
34 INT257199 Positive_regulation of Phosphorylation of Nos1 2 0.45 0.68 5.78 100.00
35 INT79121 Binding of CHSY1 2 0.27 2.39 0.58 100.00
36 INT133685 Positive_regulation of Gene_expression of NPFFR1 1 0.49 0.1 0.58 100.00
37 INT263872 Localization of Adra1d 1 0.01 2.5 0.11 99.98
38 INT77738 Transcription of SH3BP5 1 0.03 0.1 0 99.98
39 INT11624 Gene_expression of OPRM1 445 0.78 72.36 294.36 99.96
40 INT65500 Gene_expression of App 605 0.78 429.94 98.31 99.96
41 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 99.96
42 INT240171 Regulation of Chd5 1 0.26 1.52 0 99.96
43 INT6656 Gene_expression of YY1 135 0.75 24.73 72.16 99.86
44 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62 99.86
45 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 99.86
46 INT6894 Gene_expression of CNR1 168 0.78 74.07 62.84 99.86
47 INT46016 Gene_expression of Ngfr 69 0.77 41.22 19.8 99.86
48 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 99.86
49 INT86569 Gene_expression of AP2S1 2 0.15 0.55 0 99.86
50 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17 99.84
51 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29 99.84
52 INT1335 Negative_regulation of Oprl1 123 0.59 18.02 77.13 99.84
53 INT51921 Gene_expression of Cpox 501 0.73 229.81 157.81 99.84
54 INT7528 Regulation of OPRM1 100 0.62 20.63 80.57 99.84
55 INT1596 Negative_regulation of Oprl1 61 0.57 13.5 38.41 99.84
56 INT116465 Gene_expression of Birc5 241 0.78 192.31 15.32 99.84
57 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 99.84
58 INT259489 Binding of DLK1 1 0.45 6.52 0.21 99.84
59 INT1614 Gene_expression of Oprl1 164 0.78 31.43 127.74 99.84
60 INT695 Binding of POMC 304 0.48 56.66 126.85 99.84
61 INT102112 Gene_expression of Prnp 440 0.78 209.32 22.5 99.84
62 INT8732 Positive_regulation of Gene_expression of Oprm1 76 0.70 22.59 58.83 99.84
63 INT1495 Positive_regulation of Rtcd1 91 0.54 22.93 32.43 99.84
64 INT240164 Negative_regulation of Gene_expression of Chd5 1 0.41 1.41 0 99.84
65 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73 99.84
66 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 99.84
67 INT6934 Binding of OPRD1 51 0.48 7.72 25.73 99.84
68 INT768 Positive_regulation of Oprl1 179 0.70 40.05 156.93 99.84
69 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71 99.84
70 INT329574 Phosphorylation of DLK1 1 0.80 1.52 0.08 99.84
71 INT3467 Positive_regulation of Ptger1 28 0.54 10.59 8.93 99.84
72 INT65536 Negative_regulation of Positive_regulation of Nfkb1 77 0.59 38.86 33.33 99.84
73 INT132519 Regulation of OPCML 4 0.54 5.18 0.25 99.84
74 INT153635 Positive_regulation of Gene_expression of REST 10 0.54 1.38 1.6 99.84
75 INT65537 Positive_regulation of Positive_regulation of Nfkb1 52 0.67 30.6 26.35 99.84
76 INT102253 Negative_regulation of Prnp 75 0.59 24.23 2.62 99.84
77 INT21560 Positive_regulation of Binding of Oprm1 30 0.50 7.16 32.95 99.84
78 INT19501 Gene_expression of MYCN 5 0.75 3.06 1.05 99.84
79 INT110017 Phosphorylation of Nos1 12 0.60 1.64 10.3 99.84
80 INT23645 Regulation of Scnn1a 2 0.23 1.18 0.44 99.84
81 INT22492 Binding of Enpep 10 0.47 0.7 3.2 99.84
82 INT315113 Negative_regulation of MIR34A 1 0.14 2.08 0 99.84
83 INT49219 Gene_expression of Hrh1 28 0.75 13.77 14.99 99.84
84 INT48437 Positive_regulation of SH3BP5 4 0.20 2.41 3.09 99.84
85 INT123584 Gene_expression of Trpa1 176 0.78 83 78.65 99.84
86 INT146241 Positive_regulation of Gene_expression of Trpa1 23 0.69 8.07 8.74 99.84
87 INT52392 Positive_regulation of Gene_expression of OPRD1 6 0.64 0.23 3.43 99.84
88 INT204737 Negative_regulation of Gene_expression of Prnp 32 0.59 18.96 1.03 99.84
89 INT141936 Phosphorylation of Mapt 14 0.80 10.59 0.95 99.84
90 INT286025 Positive_regulation of Phosphorylation of Mapt 1 0.45 0.59 0.08 99.84
91 INT181604 Localization of WT1 1 0.63 1.41 0.03 99.84
92 INT315107 Negative_regulation of MIR100 1 0.09 1 0 99.84
93 INT71950 Positive_regulation of Binding of PTGS2 2 0.31 0.31 0.74 99.80
94 INT16919 Gene_expression of IL36RN 48 0.48 32.78 13.83 99.80
95 INT6557 Gene_expression of Eno2 65 0.77 54.42 8.17 99.78
96 INT36314 Gene_expression of FGFR3 11 0.73 6.21 2.23 99.78
97 INT11303 Gene_expression of Avp 116 0.78 39.23 23.88 99.78
98 INT6214 Negative_regulation of Adarb1 123 0.50 26.39 89.57 99.78
99 INT80217 Gene_expression of BAZ1B 1 0.75 0.1 0.23 99.78
100 INT240180 Positive_regulation of Gene_expression of Chd5 1 0.48 9.93 0.14 99.76
101 INT22427 Gene_expression of DLK1 6 0.76 16.61 0.43 99.76
102 INT46460 Gene_expression of NAV1 288 0.78 135.51 305.75 99.76
103 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 99.76
104 INT50778 Gene_expression of Adrbk1 24 0.77 11.61 20.73 99.76
105 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 99.76
106 INT240178 Gene_expression of Nlf1 1 0.08 2.94 0 99.76
107 INT329576 Negative_regulation of Gene_expression of DLK1 1 0.57 3.78 0 99.76
108 INT240174 Positive_regulation of Gene_expression of Nlf1 1 0.06 1.26 0 99.76
109 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 99.76
110 INT282434 Regulation of Gene_expression of Psen1 9 0.50 2.85 1.52 99.76
111 INT131413 Positive_regulation of Gene_expression of NAV1 35 0.70 17.5 36.83 99.76
112 INT103882 Gene_expression of MECP2 17 0.76 10.47 0.96 99.76
113 INT2699 Binding of Cpe 40 0.48 7.07 33.64 99.76
114 INT5959 Protein_catabolism of Cpe 17 0.90 0.98 12.43 99.76
115 INT2197 Gene_expression of Gnrh1 184 0.78 40.04 50.57 99.76
116 INT65598 Negative_regulation of Positive_regulation of Casp3 45 0.59 18.36 28.59 99.76
117 INT13907 Gene_expression of SCLC1 16 0.59 16.58 1.89 99.74
118 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 99.72
119 INT50673 Positive_regulation of Gene_expression of CPOX 156 0.54 97.31 37.03 99.72
120 INT107070 Gene_expression of BACE1 11 0.68 8.63 6.16 99.72
121 INT27933 Gene_expression of NCOR2 65 0.72 31.35 24.23 99.72
122 INT56805 Localization of SH3BP5 2 0.70 0.42 1.25 99.72
123 INT224366 Gene_expression of Ager 111 0.77 125.37 8.49 99.72
124 INT188123 Gene_expression of Slc9a1 12 0.75 6.75 0.9 99.72
125 INT56806 Negative_regulation of Localization of SH3BP5 1 0.37 0.2 0.5 99.72
126 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 99.72
127 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18 99.72
128 INT137797 Positive_regulation of Gene_expression of BACE1 2 0.59 2.15 1.99 99.72
129 INT130098 Negative_regulation of NOTCH1 11 0.42 5.45 1.33 99.72
130 INT44954 Gene_expression of APP 191 0.78 105.86 23.9 99.70
131 INT234255 Transcription of APP 2 0.49 0.98 0 99.70
132 INT2365 Positive_regulation of Cck 354 0.70 87.8 277.41 99.70
133 INT11439 Positive_regulation of Csf2 105 0.69 62.63 37.77 99.70
134 INT6437 Binding of YY1 154 0.47 26.3 90.46 99.68
135 INT127137 Gene_expression of TECR 4 0.30 2.08 2.74 99.68
136 INT55917 Binding of Sigmar1 26 0.45 12.65 5.58 99.68
137 INT26508 Regulation of Serpini1 2 0.19 0.84 1.01 99.68
138 INT127136 Positive_regulation of Gene_expression of TECR 1 0.20 0.32 0.87 99.68
139 INT12502 Regulation of Adarb1 50 0.53 7.58 30.01 99.68
140 INT319778 Regulation of Localization of Dio1 1 0.24 0.29 0 99.66
141 INT185886 Gene_expression of JUP 20 0.75 15.41 0.32 99.64
142 INT12838 Gene_expression of SIGMAR1 30 0.78 3.52 6.81 99.64
143 INT242174 Negative_regulation of Gene_expression of JUP 2 0.41 2.58 0 99.64
144 INT88733 Gene_expression of NPFFR2 6 0.77 1.33 4.29 99.64
145 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43 99.64
146 INT97667 Positive_regulation of Gene_expression of NPFFR2 2 0.49 0.19 0.79 99.64
147 INT97265 Gene_expression of Npffr2 8 0.56 2.54 5.72 99.64
148 INT111510 Positive_regulation of Gene_expression of Npffr2 2 0.36 0.27 1.28 99.64
149 INT443 Localization of POMC 1020 0.81 284.52 443.17 99.62
150 INT7376 Positive_regulation of CAMP 17 0.67 6.39 6.6 99.62
151 INT11429 Gene_expression of ADCY1 26 0.74 5.89 11.93 99.62
152 INT110245 Gene_expression of SNCA 11 0.77 8.29 3.36 99.62
153 INT110244 Positive_regulation of Gene_expression of SNCA 5 0.69 4.66 1.19 99.62
154 INT36668 Localization of TSC22D3 2 0.05 0.34 0.35 99.62
155 INT4768 Positive_regulation of OPRM1 212 0.70 31.09 164.28 99.60
156 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99 99.60
157 INT2289 Gene_expression of PENK 203 0.78 55.62 79.49 99.60
158 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12 99.60
159 INT64171 Regulation of CPOX 109 0.36 55.36 32.96 99.60
160 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 99.60
161 INT6849 Localization of IL1B 229 0.81 112.56 69.63 99.60
162 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 99.60
163 INT1416 Transcription of POMC 40 0.72 10.71 15.38 99.60
164 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132 99.60
165 INT123530 Phosphorylation of RELA 9 0.80 3.46 1.99 99.60
166 INT103474 Regulation of Gene_expression of BDNF 40 0.60 12.14 9.65 99.60
167 INT5045 Regulation of VIP 26 0.62 7.15 11.61 99.60
168 INT129296 Phosphorylation of IKBKE 1 0.35 0.54 0.63 99.60
169 INT134747 Gene_expression of SV2A 10 0.72 0.44 3.48 99.60
170 INT134749 Gene_expression of TEAD1 9 0.48 3.61 3.15 99.60
171 INT12082 Localization of IL6 365 0.81 241.78 105.78 99.60
172 INT37435 Negative_regulation of Tyr 6 0.14 0.96 2.94 99.60
173 INT49136 Gene_expression of Ptgdr 16 0.67 1.66 7.05 99.60
174 INT129297 Positive_regulation of Phosphorylation of RELA 1 0.24 0.33 0.29 99.60
175 INT86124 Regulation of Mgat2 1 0.25 0.62 0 99.60
176 INT22128 Positive_regulation of HIVEP1 61 0.43 70.52 6.07 99.60
177 INT159946 Gene_expression of Mat1a 23 0.77 15.33 7.49 99.60
178 INT201393 Positive_regulation of Regulation of CPOX 1 0.09 1.51 0.98 99.60
179 INT57228 Gene_expression of NPVF 3 0.64 0.81 0.53 99.60
180 INT261680 Positive_regulation of Negative_regulation of MAPK1 2 0.33 1.2 0.21 99.60
181 INT182995 Gene_expression of KCNIP3 19 0.69 13.28 8.81 99.58
182 INT12475 Gene_expression of OPRL1 35 0.77 3.63 23.11 99.58
183 INT1156 Binding of CCK 27 0.48 8.71 20.58 99.58
184 INT32778 Gene_expression of Mettl15 6 0.70 0.98 5.86 99.56
185 INT136535 Gene_expression of Nrgn 3 0.78 3.2 3.65 99.56
186 INT1491 Regulation of Rtcd1 33 0.53 5.17 13.4 99.56
187 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83 99.56
188 INT65009 Gene_expression of HTR3A 29 0.75 8.51 10.59 99.56
189 INT33315 Regulation of Regulation of Rtcd1 2 0.02 0.49 0.43 99.56
190 INT32777 Regulation of Gene_expression of Mettl15 1 0.56 0.2 0.78 99.56
191 INT69570 Binding of Prnp 75 0.48 44.26 4.37 99.56
192 INT268171 Negative_regulation of Binding of Prnp 3 0.42 0.82 0.25 99.56
193 INT245028 Negative_regulation of Gene_expression of Xrcc1 1 0.43 0.62 0 99.56
194 INT125947 Gene_expression of Adora2b 57 0.75 23.69 17 99.54
195 INT15042 Gene_expression of Adora2a 37 0.77 3.77 14.24 99.54
196 INT66374 Positive_regulation of Localization of RTCA 1 0.18 0.31 0.57 99.54
197 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 99.54
198 INT10763 Localization of IL2 157 0.80 81.11 33.21 99.52
199 INT79441 Localization of XCL1 5 0.62 3.98 2 99.52
200 INT69483 Transcription of OPRM1 45 0.72 7.31 30.22 99.52
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