D:Neurodegenerative Disease

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Disease Term
Synonyms DEGENERATIVE CONDITION NEUROLOGIC, DEGENERATIVE CONDITIONS NEUROLOGIC, Degenerative Disease Of Nervous System, Degenerative Diseases Central Nervous System, Degenerative Diseases Nervous System, Degenerative Diseases Neurologic, Degenerative Diseases Of Nervous System, Degenerative Diseases Spinal Cord, DEGENERATIVE NEUROLOGIC DISEASE, DEGENERATIVE NEUROLOGIC DISEASES, Degenerative Neurologic Disorder
Documents 2155
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Neurodegenerative Disease. They are ordered first by their relevance to Neurodegenerative Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT325059 Insr Positive_regulation of Ang 1 0.02 1.4 0.08 100.00
2 INT325058 Igf1 Positive_regulation of Ang 1 0.04 1.4 0.08 100.00
3 INT325056 Binding of E2f1 and Ang 1 0.06 1.3 0.12 100.00
4 INT325057 Binding of Hand1 and Ang 1 0.01 1.29 0.12 100.00
5 INT157211 Binding of AGXT and WNK1 1 0.07 0.68 0.22 100.00
6 INT157212 Binding of SPTLC1 and WNK1 1 0.07 0.67 0.22 100.00
7 INT157216 Binding of SPTLC2 and WNK1 1 0.03 0.68 0.22 100.00
8 INT157214 Binding of SGCG and SPTLC2 1 0.14 0.68 0.22 100.00
9 INT157213 Binding of AGXT and SGCG 1 0.30 0.68 0.22 100.00
10 INT157215 Binding of SGCG and SPTLC1 1 0.32 0.67 0.22 100.00
11 INT175196 Binding of NCOR1 and NUP62 1 0.02 0.84 0.12 100.00
12 INT243216 Myst2 Positive_regulation of Gene_expression of VEGFA 1 0.00 0.75 0.11 100.00
13 INT298257 Pou4f1 Negative_regulation of Proc 1 0.01 0.54 0.03 100.00
14 INT320554 Mapk14 Positive_regulation of MEF2A 1 0.26 1.31 0 99.96
15 INT243215 Myst2 Negative_regulation of Gene_expression of Icam1 1 0.01 0.68 0.1 99.80
16 INT340742 Positive_regulation of CSF2 Regulation of BDNF 1 0.22 1.46 0.14 99.64
17 INT204880 Tlr4 Positive_regulation of Cp 1 0.56 0.63 0.07 99.56
18 INT305744 Fst Positive_regulation of Creb1 1 0.12 0.33 0.57 99.44
19 INT305732 Tst Positive_regulation of Creb1 1 0.12 0.33 0.57 99.44
20 INT103092 Binding of PPARA and ISYNA1 1 0.01 0.45 0.54 99.40
21 INT308648 Binding of sps and Gopc 1 0.01 2.71 0 99.40
22 INT118082 APP Positive_regulation of Casp3 1 0.00 0.5 0.54 99.36
23 INT310494 Gene_expression of Dlx2 Positive_regulation of Fate1 1 0.04 0.1 0.18 99.32
24 INT340744 CSF2 Regulation of BDNF 1 0.13 1.45 0.14 99.28
25 INT254909 ARSH Regulation of Sumf1 1 0.00 0.9 0.04 98.90
26 INT254908 ARSH Regulation of Eef1a1 1 0.00 0.89 0.04 98.90
27 INT261380 Nsdhl Negative_regulation of P4hb 1 0.02 1.36 0.11 98.88
28 INT329004 Binding of MPZ and RNF123 1 0.00 0.7 0 98.72
29 INT329012 Binding of MPZ and Nedd4 1 0.03 0.7 0 98.72
30 INT329007 Binding of MPZ and TSG101 1 0.01 0.71 0 98.72
31 INT273040 Vip Regulation of Bax 1 0.23 1.69 0.13 98.64
32 INT273041 Adcyap1 Regulation of Bax 1 0.21 1.69 0.13 98.64
33 INT283716 Neurod1 Positive_regulation of Pax6 1 0.23 0.46 0 98.60
34 INT261391 Binding of Nsdhl and P4hb 1 0.02 1.3 0.1 98.52
35 INT249598 Stat1 Positive_regulation of Gene_expression of Cd40 1 0.41 0.46 0.14 98.40
36 INT329013 Binding of LITAF and Nedd4 1 0.15 1.4 0 98.36
37 INT329008 Binding of LITAF and RNF123 1 0.01 1.39 0 98.36
38 INT329005 Binding of TSG101 and LITAF 1 0.04 1.41 0 98.36
39 INT340743 Negative_regulation of CSF2 Positive_regulation of ZNF807 1 0.00 1.77 0 98.36
40 INT346913 Binding of Kars and Positive_regulation of Gene_expression of Ros1 1 0.03 1.25 0.46 98.24
41 INT107564 Hps4 Regulation of Localization of Il1b 1 0.01 0.1 1.07 98.24
42 INT107560 Penk Regulation of Localization of Il1b 1 0.18 0.1 1.07 98.24
43 INT107566 Penk Regulation of Hps4 1 0.00 0.1 1.04 98.24
44 INT107563 Penk Regulation of Mtr 1 0.00 0.1 1.04 98.24
45 INT107565 Hps4 Regulation of Mtr 1 0.00 0.1 1.04 98.24
46 INT252631 Binding of Casp3 and Tnfrsf1a 1 0.10 0.69 0.13 98.16
47 INT235775 Binding of Tnfrsf1a and Tradd 3 0.31 3 0.12 98.16
48 INT221963 ELAVL1 Regulation of Gene_expression of CDK5R1 1 0.01 0.58 0.03 97.88
49 INT263587 Pdia3 Negative_regulation of Binding of Esr1 1 0.07 1.86 0.26 97.84
50 INT252632 Binding of Casp3 and Tradd 1 0.11 0.68 0.12 97.72
51 INT255658 Coq10a Regulation of Negative_regulation of Rgc32 1 0.01 1.14 0.14 97.68
52 INT340745 CSF2 Positive_regulation of ZNF807 1 0.00 1.76 0 97.64
53 INT262825 Serpinf1 Negative_regulation of Gfap 1 0.34 0.87 0.08 97.44
54 INT280949 Binding of Fst and Inhbe 3 0.01 2.51 1.15 97.20
55 INT346914 Binding of Kars and Positive_regulation of Gene_expression of Car2 1 0.05 1.24 0.45 96.96
56 INT201755 ROS1 Positive_regulation of Casp3 1 0.00 1.4 0 96.92
57 INT115597 Avp Positive_regulation of Crh 1 0.56 0.79 0.31 96.88
58 INT210953 Binding of VEGFA and Csf2 1 0.00 0.47 0.3 96.76
59 INT223930 Binding of Akt1 and Pik3cb 1 0.07 0.35 0.26 96.76
60 INT223929 Negative_regulation of Binding of Akt1 and Pik3cb 1 0.08 0.36 0.26 96.76
61 INT242642 Binding of BDNF and Ngfr 2 0.21 1.38 1.01 96.68
62 INT261390 Binding of Nsdhl and Bdnf 1 0.05 1.33 0.12 96.52
63 INT220724 Binding of IGFALS and SOD1 1 0.06 2.1 0.06 96.48
64 INT310498 Gene_expression of Neurog2 Positive_regulation of Positive_regulation of Eomes 1 0.20 0.42 0.19 96.00
65 INT128654 ITIH4 Regulation of Gene_expression of CCL16 1 0.02 2.69 1.79 95.80
66 INT261387 Nsdhl Negative_regulation of Casp3 1 0.03 1.08 0.19 95.78
67 INT221958 CDK5R1 Positive_regulation of Positive_regulation of CDK5 1 0.36 0.38 0.1 95.64
68 INT262821 Serpinf1 Negative_regulation of Gene_expression of Il18 1 0.54 0.85 0.08 95.52
69 INT220725 Binding of IGFALS and IGHD1OR15-1A 1 0.01 1.05 0.03 95.48
70 INT98671 ROS1 Positive_regulation of Gene_expression of Penk 1 0.00 0.52 0.25 95.28
71 INT221959 Binding of CDK5 and CDK5R1 1 0.28 0.53 0.1 95.16
72 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62 95.08
73 INT319763 Large Positive_regulation of Transcription of Nes 1 0.14 0.2 0.03 95.08
74 INT310497 Neurog2 Positive_regulation of Fate1 1 0.07 0.36 0.21 95.08
75 INT320451 ECT Positive_regulation of Gene_expression of BDNF 1 0.05 1.21 0.49 95.04
76 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31 95.04
77 INT280951 Tlr4 Positive_regulation of Localization of S100a8 1 0.01 1.09 0.69 94.88
78 INT262826 Serpinf1 Negative_regulation of Gene_expression of TNF 1 0.29 1.83 0.28 94.72
79 INT152947 Dlg4 Regulation of Sgk1 1 0.09 0.18 0.76 94.60
80 INT152945 Dlg4 Regulation of Cap1 1 0.11 0.18 0.76 94.60
81 INT152949 Homer1 Regulation of Sgk1 1 0.28 0.18 0.76 94.60
82 INT152946 Homer1 Regulation of Cap1 1 0.32 0.18 0.76 94.60
83 INT152948 Homer1 Regulation of Gpr88 1 0.36 0.18 0.75 94.60
84 INT152944 Dlg4 Regulation of Gpr88 1 0.12 0.18 0.75 94.60
85 INT226043 Epo Positive_regulation of Ecm1 1 0.04 1.35 0.05 94.48
86 INT91811 Binding of FAS and TP53 1 0.21 1.1 0.16 94.32
87 INT91813 Binding of FAS and FASLG 4 0.23 9.89 0.99 94.32
88 INT80030 Binding of FAS and TNF 3 0.27 2.54 0.56 94.32
89 INT252143 Bdnf Regulation of Gene_expression of Npy 1 0.11 0.49 0 94.16
90 INT313993 Ros1 Positive_regulation of Nfkb1 1 0.05 1.61 0.68 94.00
91 INT107562 Penk Positive_regulation of Localization of Il1b 1 0.20 0.09 1.09 94.00
92 INT107561 Mtr Positive_regulation of Localization of Il1b 1 0.04 0.09 1.09 94.00
93 INT245555 Runx1 Negative_regulation of Cdkn1a 1 0.29 1.17 0.23 93.96
94 INT245565 Runx1 Negative_regulation of Negative_regulation of Cdkn1a 1 0.29 1.17 0.23 93.96
95 INT91814 Binding of TNF and TP53 1 0.14 2.2 0.32 93.68
96 INT91810 Binding of FASLG and TNF 1 0.05 0.92 0.08 93.68
97 INT305742 Binding of Sort1 and Gtf3a 1 0.01 0.64 0.88 93.60
98 INT303338 Binding of ULK1 and Atg13 1 0.07 0.73 0 93.60
99 INT152298 Mmp9 Negative_regulation of Tsc22d1 1 0.13 0.16 0.66 93.60
100 INT152299 Mmp2 Negative_regulation of Tsc22d1 1 0.16 0.16 0.66 93.60
101 INT152296 Regulation of Mmp9 Negative_regulation of Tsc22d1 1 0.08 0.16 0.66 93.60
102 INT200059 Gtf3a Positive_regulation of Ndn 1 0.06 0.89 0 93.40
103 INT319765 Large Positive_regulation of Gopc 1 0.08 0.15 0.03 93.12
104 INT319766 Large Positive_regulation of Nes 1 0.20 0.15 0.03 93.12
105 INT131312 Binding of Nts and Datd 1 0.10 0.74 0.46 93.04
106 INT305738 Binding of Creb1 and Atf6b 1 0.08 0.34 0.53 93.00
107 INT272365 Gene_expression of Adarb1 Positive_regulation of Gene_expression of GRIA1 1 0.00 0.26 0.09 93.00
108 INT250253 Binding of AQP4 and SLC1A2 1 0.30 2.95 1.09 92.88
109 INT91812 Binding of FASLG and TP53 1 0.04 1.1 0.16 92.72
110 INT344878 ENPEP Regulation of Gene_expression of Mapt 1 0.09 0.33 0 92.72
111 INT344881 ENPEP Regulation of Mapt 1 0.05 0.33 0 92.72
112 INT177396 Npy1r Positive_regulation of Negative_regulation of Npy 1 0.27 0.38 0.37 92.64
113 INT135641 Binding of Dst and Ina 1 0.35 0.34 0.06 92.60
114 INT114676 Mdm2 Negative_regulation of p53-ps 1 0.10 0.26 0.48 92.56
115 INT159962 Rock2 Regulation of Localization of Il6 1 0.09 2.7 0.88 92.24
116 INT251582 TNF Positive_regulation of Tnfrsf1b 1 0.29 2.11 0.32 92.16
117 INT152297 Mmp2 Negative_regulation of Mmp9 1 0.39 0.16 0.65 92.12
118 INT177400 RNY1 Positive_regulation of Negative_regulation of Npy 1 0.03 0.38 0.37 92.08
119 INT167619 Protein_catabolism of Ppp2cb Positive_regulation of App 1 0.00 0.88 0.44 92.04
120 INT107567 Hps4 Positive_regulation of Localization of Il1b 1 0.01 0.09 1.08 92.00
121 INT127503 Mpz Positive_regulation of Ptgs1 1 0.14 0.9 0.18 91.92
122 INT102201 Tnf Regulation of Il1b 3 0.39 2.57 0.82 91.88
123 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39 91.80
124 INT281881 Binding of Aco1 and Ros1 1 0.01 1.93 0.1 91.72
125 INT264134 Binding of IFNA1 and Tlr4 1 0.01 1.5 0.22 91.68
126 INT295260 Positive_regulation of Nfe2l2 Positive_regulation of Gene_expression of Gclm 1 0.26 0.23 0.07 91.44
127 INT262822 Serpinf1 Negative_regulation of Negative_regulation of 1190002H23Rik 1 0.07 1.27 0.18 91.36
128 INT273233 Negative_regulation of Cdk5 Negative_regulation of Positive_regulation of Ltp 1 0.20 0.39 0.13 91.32
129 INT252140 Binding of Cck and Snap25 1 0.30 0.39 0.3 91.28
130 INT100597 Regulation of RPL21P132 Positive_regulation of IL6 1 0.01 0.45 0.53 91.08
131 INT159963 Tnf Positive_regulation of Localization of Il6 1 0.12 2.32 0.71 90.92
132 INT283543 Binding of GARS and Setx 1 0.01 3.71 0 90.88
133 INT283533 Binding of GARS and SPG19 1 0.00 1.72 0 90.88
134 INT132148 LTF Positive_regulation of TP53 1 0.44 0.56 0.13 90.80
135 INT308965 Binding of Cnr2 and Gpbar1 1 0.03 0.61 0.25 90.76
136 INT63511 F2 Negative_regulation of SERPINE2 1 0.15 0.97 0.16 90.68
137 INT221962 UTS2R Regulation of Gene_expression of CDK5R1 1 0.09 0.43 0.03 90.52
138 INT78348 Binding of GALR1 and GAL 4 0.41 1.47 0.8 90.40
139 INT152164 Binding of GALR3 and GAL 2 0.31 0.88 0.39 90.40
140 INT224908 Binding of SLC6A7 and GAL 1 0.17 0.37 0.22 90.40
141 INT224904 Binding of GALR2 and GAL 1 0.16 0.37 0.22 90.40
142 INT135095 Negative_regulation of CTSB Negative_regulation of APP 1 0.00 0.74 0.3 90.36
143 INT261398 Nsdhl Positive_regulation of Binding of Nsdhl and Med1 1 0.01 2.14 0.09 90.32
144 INT261393 Binding of Nsdhl and Med1 1 0.02 1 0.04 90.32
145 INT304575 Creb1 Regulation of Gene_expression of Bdnf 1 0.04 1 0.84 90.28
146 INT261579 Serpinc1 Negative_regulation of Gene_expression of CYBB 1 0.00 1.69 0.18 90.24
147 INT261375 Binding of Nsdhl and Pparg 1 0.05 1.03 0.25 90.20
148 INT291394 Gene_expression of HTT Negative_regulation of Gene_expression of Slc1a2 1 0.11 0.96 0.34 90.08
149 INT340608 Binding of Creb1 and Wnt3a 1 0.30 0.24 0.14 89.96
150 INT122567 Mog Positive_regulation of Eae1 8 0.31 10.18 4.26 89.96
151 INT201273 Nos2 Regulation of Nos1 1 0.17 0.99 0.23 89.92
152 INT215290 Siglec1 Negative_regulation of Decr1 1 0.00 0.68 0.41 89.84
153 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25 89.68
154 INT273902 Mtor Positive_regulation of Eif4ebp1 1 0.50 0.56 0.15 89.68
155 INT283542 Binding of SPG19 and Setx 1 0.06 3.69 0 89.60
156 INT316111 APC Negative_regulation of SAE1 1 0.04 1.21 0.22 89.60
157 INT217651 Binding of ROS1 and fa 1 0.01 1.09 0.07 89.40
158 INT167617 Bace2 Positive_regulation of App 1 0.06 0.87 0.44 89.20
159 INT235084 IL6 Positive_regulation of Gene_expression of ISYNA1 1 0.02 1.11 0.2 89.20
160 INT221954 Binding of CDK5 and CDK5R2 1 0.02 0.36 0.09 89.04
161 INT254906 Binding of Igfals and Chmp2b 1 0.02 0.85 0 88.96
162 INT306560 BMP4 Positive_regulation of MAPK1 1 0.09 0.09 0.03 88.92
163 INT235870 Bdnf Regulation of Gene_expression of Slc6a4 1 0.09 0.77 0.5 88.84
164 INT305205 Binding of Epo and Pbrgcsf1 1 0.14 0.23 0.07 88.80
165 INT316110 Binding of APC and SAE1 1 0.03 1.16 0.2 88.80
166 INT295920 Mir761 Positive_regulation of Transcription of Bcl2l1 1 0.00 1.43 0 88.44
167 INT129694 Binding of Casp3 and Casp9 1 0.35 0.86 0.65 88.32
168 INT167621 Psenen Positive_regulation of App 1 0.02 0.86 0.44 88.28
169 INT250152 Binding of APOE and UBE4B 1 0.21 1.2 0 88.16
170 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71 88.08
171 INT261396 Nsdhl Positive_regulation of Transcription of Esr1 1 0.02 2.1 0.09 88.08
172 INT273901 Mtor Positive_regulation of Eif4e 1 0.50 0.54 0.14 87.84
173 INT200057 Binding of Ndn and Ngfr 1 0.43 1.96 0 87.72
174 INT204895 Tlr4 Positive_regulation of Gene_expression of Cp 1 0.38 0.47 0.09 87.68
175 INT262708 Bace1 Positive_regulation of Gene_expression of App 1 0.44 2.82 0 87.68
176 INT204903 Gopc Positive_regulation of Gene_expression of Cp 1 0.16 0.26 0.05 87.52
177 INT291568 Artles Regulation of Cstb 1 0.00 0.7 0.3 87.36
178 INT100596 RPL21P132 Positive_regulation of TNF 1 0.00 0.43 0.5 87.24
179 INT100595 RPL21P132 Positive_regulation of IL6 1 0.01 0.43 0.49 87.24
180 INT231244 Binding of Fus and Alms1 1 0.20 0.57 0.17 87.24
181 INT130531 BACE1 Regulation of Gene_expression of BACE2 1 0.40 0.18 0 87.24
182 INT130533 BACE1 Regulation of SNAP25 1 0.27 0.18 0 87.24
183 INT130532 BACE2 Regulation of SNAP25 1 0.12 0.18 0 87.24
184 INT354123 MIR124-1 Negative_regulation of Gene_expression of CTDSP1 1 0.01 0.15 0 86.96
185 INT325430 Vsnl1 Positive_regulation of Vhl-ps1 1 0.03 1.01 0 86.84
186 INT325432 Vsnl1 Positive_regulation of Csf2 1 0.19 1.07 0 86.84
187 INT305203 Epo Positive_regulation of Gene_expression of Neurog1 1 0.06 0.4 0.21 86.32
188 INT266402 Binding of S100P and Ager 1 0.00 2.25 0.35 85.92
189 INT217109 Hoxa2 Positive_regulation of Egr2 1 0.56 0.43 0 85.64
190 INT317399 Binding of Acc and Amp1 1 0.05 0.55 0.11 85.52
191 INT159964 Tnf Positive_regulation of Phosphorylation of Mapk8 1 0.11 0.94 0.29 85.36
192 INT317394 Binding of Stk11 and Amp1 1 0.04 0.89 0.21 85.20
193 INT266413 Positive_regulation of Binding of HMGB1 and Col4a1 1 0.02 1.05 0.14 85.20
194 INT258204 LPA Positive_regulation of GTPBP4 1 0.00 0.29 0 84.88
195 INT290594 BDNF Positive_regulation of Localization of S100B 1 0.08 0.6 0.57 84.84
196 INT298876 RAB7A Positive_regulation of Protein_catabolism of NTRK1 1 0.14 0.44 0.22 84.80
197 INT305731 Binding of Bdnf and Creb1 Positive_regulation of BDNF 1 0.11 0.49 0.47 84.76
198 INT305735 Binding of Bdnf and Creb1 1 0.08 0.49 0.47 84.76
199 INT305747 Binding of Bdnf and Creb1 Positive_regulation of Bdnf 1 0.03 0.49 0.47 84.76
200 INT305746 Positive_regulation of Creb1 Positive_regulation of BDNF 1 0.32 0.41 0.47 84.76

Single Events

The table below shows the top 200 pain related interactions that have been reported for Neurodegenerative Disease. They are ordered first by their pain relevance and then by number of times they were reported in Neurodegenerative Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT65731 Gene_expression of Cnr1 234 0.78 63.82 109.34 100.00
2 INT280945 Positive_regulation of Gene_expression of Inhbe 1 0.06 7.07 2.31 100.00
3 INT90785 Negative_regulation of Ang 3 0.42 8.34 1.06 100.00
4 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 100.00
5 INT202868 Positive_regulation of Car1 30 0.44 15.48 7.42 100.00
6 INT14880 Positive_regulation of Car3 14 0.65 9.19 3.73 100.00
7 INT87314 Gene_expression of Htt 112 0.78 55.82 3.03 100.00
8 INT347920 Regulation of Scpro1 1 0.00 3.74 0.25 100.00
9 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 100.00
10 INT228545 Regulation of Coq10a 8 0.42 5.62 0.23 100.00
11 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 100.00
12 INT12003 Gene_expression of Ang 4 0.64 3.87 0.44 100.00
13 INT116464 Negative_regulation of Birc5 53 0.59 45.4 4.91 100.00
14 INT116619 Positive_regulation of Positive_regulation of Creb1 25 0.69 8.32 7.3 100.00
15 INT175507 Regulation of Gene_expression of Bax 13 0.50 10.91 0.95 100.00
16 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76 100.00
17 INT245671 Positive_regulation of Gene_expression of Car1 15 0.28 4.31 2.67 100.00
18 INT32693 Positive_regulation of Gene_expression of Car3 6 0.42 2.7 0.89 100.00
19 INT325052 Regulation of Negative_regulation of Ang 1 0.10 1.08 0.11 100.00
20 INT107341 Phosphorylation of MAPT 19 0.80 14 1.61 100.00
21 INT12004 Localization of Ang 3 0.39 1.3 0.31 100.00
22 INT340595 Positive_regulation of Gene_expression of Wnt3a 1 0.61 0.86 3.11 100.00
23 INT73365 Positive_regulation of Ang 10 0.67 3.8 1.36 100.00
24 INT347922 Negative_regulation of Scpro1 1 0.00 2.75 0.1 100.00
25 INT100601 Localization of PRNP 17 0.66 13.61 0.71 100.00
26 INT76551 Regulation of Ang 7 0.45 2.6 0.9 100.00
27 INT86729 Positive_regulation of CDCP1 37 0.07 18.74 10.76 100.00
28 INT159119 Negative_regulation of Car1 17 0.37 6.6 4.01 100.00
29 INT128353 Negative_regulation of Car3 16 0.37 4.93 4.61 100.00
30 INT153853 Positive_regulation of Fus 7 0.42 8.43 1.59 100.00
31 INT176517 Negative_regulation of Gene_expression of Spp1 18 0.59 15.31 2.28 100.00
32 INT240278 Localization of IGFALS 11 0.53 9.44 0.29 100.00
33 INT16131 Negative_regulation of GBE1 37 0.30 10.32 8.15 100.00
34 INT294807 Regulation of Negative_regulation of Birc5 1 0.45 1.05 0 100.00
35 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03 100.00
36 INT91147 Positive_regulation of Positive_regulation of Ppara 30 0.69 19.31 5.56 100.00
37 INT160799 Regulation of IGFALS 11 0.29 9.09 0.7 100.00
38 INT338882 Regulation of Regulation of Mecp2 1 0.24 0.56 0.29 100.00
39 INT233571 Regulation of Apod 4 0.59 4.54 0.15 100.00
40 INT106318 Gene_expression of S100A4 21 0.75 12.13 3.23 100.00
41 INT169670 Gene_expression of PHARC 1 0.14 1.41 0.35 100.00
42 INT216374 Positive_regulation of Gene_expression of PAX3 1 0.26 0.31 0.05 100.00
43 INT216385 Positive_regulation of PAX3 1 0.26 0.31 0.05 100.00
44 INT276 Regulation of Ache 83 0.62 16.75 25.99 100.00
45 INT140081 Positive_regulation of NAIP 2 0.67 0.75 0.4 100.00
46 INT346911 Positive_regulation of Nlrp10 1 0.21 0.74 0.4 100.00
47 INT88917 Positive_regulation of Casp8 18 0.60 14.64 1.36 100.00
48 INT352818 Gene_expression of Nudt4 1 0.57 1.98 0.12 100.00
49 INT136791 Negative_regulation of Spp1 24 0.59 23.6 3.33 100.00
50 INT11508 Positive_regulation of TGFBI 24 0.70 19.81 15.78 100.00
51 INT86361 Positive_regulation of Positive_regulation of NOS1 39 0.53 18.93 10.42 100.00
52 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4 100.00
53 INT27551 Gene_expression of SERPINH1 45 0.62 42.87 9.04 100.00
54 INT35058 Positive_regulation of PLAUR 11 0.61 7.21 2.16 100.00
55 INT143442 Positive_regulation of NRP1 11 0.57 2.62 0.3 100.00
56 INT311121 Localization of Ctsa 1 0.11 0.74 0.28 100.00
57 INT338869 Regulation of Regulation of Fmr1 1 0.11 0.29 0.15 100.00
58 INT338872 Regulation of Regulation of Creb1 1 0.21 0.28 0.15 100.00
59 INT325044 Binding of Ang 1 0.12 0.47 0.12 100.00
60 INT244605 Gene_expression of BASP1 2 0.56 0.92 0 100.00
61 INT356152 Negative_regulation of Mkrn2 1 0.24 0.33 0 100.00
62 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 99.98
63 INT116463 Negative_regulation of Gene_expression of Birc5 40 0.59 33.99 2.74 99.98
64 INT156666 Positive_regulation of Localization of Igf1 11 0.62 6.94 1.95 99.98
65 INT151032 Localization of Igf1 49 0.76 26.32 5.71 99.98
66 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5 99.98
67 INT1893 Localization of Gh 1041 0.79 340.23 256.58 99.98
68 INT130728 Binding of MMP1 14 0.47 4.7 1.95 99.98
69 INT214414 Binding of FGR 1 0.01 1.4 0.44 99.98
70 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.96
71 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 99.96
72 INT302340 Positive_regulation of Gene_expression of Dlx2 2 0.64 3.43 2.15 99.96
73 INT102020 Gene_expression of Creb1 190 0.78 57.31 59.77 99.96
74 INT182312 Positive_regulation of Gene_expression of Birc5 26 0.69 25.3 2.32 99.96
75 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58 99.96
76 INT201565 Positive_regulation of Gene_expression of NPC1 5 0.43 5.94 0.26 99.96
77 INT13995 Gene_expression of gr 96 0.74 48.21 26.54 99.96
78 INT310462 Positive_regulation of Gene_expression of Ascl1 1 0.37 0.52 0.17 99.96
79 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41 99.96
80 INT50334 Negative_regulation of Cnr1 84 0.58 30.86 51.75 99.92
81 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62 99.92
82 INT23657 Positive_regulation of APP 64 0.70 39.76 16.68 99.92
83 INT99823 Positive_regulation of Gene_expression of APP 31 0.70 21.52 5.09 99.92
84 INT15990 Binding of Gfm1 10 0.31 8.53 1.37 99.92
85 INT235665 Positive_regulation of Pcdhb16 3 0.08 3.18 0.22 99.92
86 INT74389 Gene_expression of Gdnf 131 0.78 58.52 57.06 99.92
87 INT215327 Positive_regulation of Gene_expression of Vdac1 12 0.16 5.79 0 99.92
88 INT114138 Gene_expression of Vdac1 18 0.59 7.07 0.53 99.92
89 INT4866 Positive_regulation of GAL 32 0.67 13.02 16.16 99.92
90 INT25 Positive_regulation of LAMC2 19 0.67 8.64 7.06 99.92
91 INT10855 Positive_regulation of Gene_expression of LAMC2 4 0.67 2.05 0.88 99.92
92 INT82055 Positive_regulation of Creb1 176 0.70 60.2 58.39 99.90
93 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 99.90
94 INT1767 Positive_regulation of PROC 83 0.67 54.14 17 99.90
95 INT115074 Positive_regulation of GRIA1 10 0.67 2.66 4.48 99.90
96 INT106274 Positive_regulation of Syt1 16 0.67 9.76 4.1 99.90
97 INT230964 Positive_regulation of SLC16A7 1 0.07 0.1 0 99.90
98 INT230960 Positive_regulation of SNCAIP 1 0.09 0.1 0 99.90
99 INT29705 Regulation of Positive_regulation of Casp3 13 0.48 5.37 10.45 99.88
100 INT244608 Gene_expression of IKZF5 1 0.32 0.33 0 99.88
101 INT5851 Positive_regulation of Gene_expression of Penk 52 0.70 14.57 25.05 99.86
102 INT30276 Positive_regulation of Gene_expression of Pdyn 39 0.67 11.28 24.89 99.86
103 INT113007 Positive_regulation of Positive_regulation of Pdyn 7 0.49 2.28 2.68 99.86
104 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36 99.86
105 INT81628 Positive_regulation of Gene_expression of Fas 32 0.67 38.13 4.23 99.86
106 INT277880 Gene_expression of Tas2r111-ps2 1 0.13 1.22 0 99.86
107 INT61316 Gene_expression of Coq10a 59 0.73 32.81 3.95 99.84
108 INT66005 Regulation of Cnr1 47 0.61 19.21 34.52 99.84
109 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 99.84
110 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 99.84
111 INT183681 Positive_regulation of Tlr3 20 0.62 16.25 4.54 99.84
112 INT69435 Negative_regulation of ROS1 74 0.51 50.38 13.71 99.84
113 INT254194 Regulation of Positive_regulation of Tlr3 2 0.52 0.79 0.19 99.84
114 INT51163 Gene_expression of Gal 119 0.78 67.48 49.23 99.84
115 INT82531 Positive_regulation of Gene_expression of Gal 41 0.69 28.67 18.04 99.84
116 INT164587 Gene_expression of MCL1 94 0.75 124.05 5.39 99.84
117 INT18360 Regulation of MRXS5 11 0.32 7.07 2.17 99.84
118 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68 99.82
119 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132 99.82
120 INT18340 Gene_expression of CRX 16 0.22 13.85 7.13 99.82
121 INT129910 Positive_regulation of Inhbe 2 0.05 3.84 1.07 99.80
122 INT280934 Positive_regulation of Regulation of Inhbe 1 0.04 2.84 0.68 99.80
123 INT1050 Gene_expression of hpc 21 0.58 5.33 4.2 99.80
124 INT56139 Negative_regulation of Gene_expression of hpc 2 0.37 2.57 0.23 99.80
125 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48 99.80
126 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 99.80
127 INT280939 Regulation of Gene_expression of Inhbe 1 0.04 1.1 0.31 99.80
128 INT93738 Gene_expression of Tnfrsf1a 63 0.74 57.66 23.09 99.80
129 INT91754 Gene_expression of Cp 42 0.77 21.97 5.38 99.80
130 INT102206 Regulation of Bdnf 37 0.62 28.54 28.78 99.80
131 INT12029 Gene_expression of Car1 143 0.67 29.69 36.39 99.80
132 INT86062 Positive_regulation of Tnfrsf1a 51 0.69 40.69 26.2 99.80
133 INT93739 Positive_regulation of Gene_expression of Tnfrsf1a 11 0.66 11.17 4.44 99.80
134 INT123787 Gene_expression of Bid 25 0.66 16 6.35 99.80
135 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71 99.80
136 INT2569 Gene_expression of Ache 120 0.78 26.29 26.89 99.78
137 INT216384 Positive_regulation of ENPP3 3 0.54 0.84 0.69 99.78
138 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51 99.78
139 INT116465 Gene_expression of Birc5 241 0.78 192.31 15.32 99.76
140 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12 99.76
141 INT66040 Positive_regulation of Bdnf 114 0.69 67.67 51.81 99.76
142 INT280943 Regulation of Inhbe 1 0.04 5.59 1.7 99.76
143 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33 99.76
144 INT130837 Gene_expression of Aqp4 205 0.78 151.23 29.63 99.76
145 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17 99.76
146 INT14301 Binding of CSF2 82 0.48 67.95 8.98 99.76
147 INT14881 Gene_expression of Car3 49 0.73 14.89 9.94 99.76
148 INT124860 Gene_expression of Bace1 330 0.78 157.11 31.65 99.76
149 INT217382 Regulation of Gene_expression of Bace1 26 0.61 17 1.76 99.76
150 INT217389 Negative_regulation of Gene_expression of Bace1 43 0.59 18.57 3.27 99.76
151 INT219355 Binding of CDK5 3 0.35 2.02 0.06 99.76
152 INT317907 Gene_expression of DLGAP2 1 0.63 0.85 0 99.76
153 INT65500 Gene_expression of App 605 0.78 429.94 98.31 99.74
154 INT7114 Positive_regulation of Ltp 1192 0.62 290.76 755.77 99.74
155 INT15745 Negative_regulation of GYPA 18 0.43 8.01 2.74 99.74
156 INT86789 Gene_expression of P2rx4 46 0.77 30.66 25.68 99.74
157 INT71690 Negative_regulation of Negative_regulation of Ntf3 2 0.36 1.3 1.01 99.74
158 INT6481 Binding of TNF 624 0.48 510.2 214.82 99.72
159 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18 99.72
160 INT4228 Gene_expression of CAT 50 0.75 20.62 7.18 99.72
161 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 99.70
162 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21 99.70
163 INT29743 Negative_regulation of App 91 0.59 65.56 31.26 99.68
164 INT64052 Positive_regulation of FGFR1 26 0.52 28.47 6.36 99.68
165 INT121910 Binding of Nrcam 4 0.03 1.51 2.26 99.68
166 INT215759 Binding of Lpar6 1 0.02 0.24 0.17 99.68
167 INT18892 Binding of HTLVR 2 0.25 1.76 0.23 99.68
168 INT310476 Negative_regulation of Gene_expression of Neurog2 1 0.40 0.71 0.21 99.68
169 INT132149 Positive_regulation of Gene_expression of LTF 10 0.70 11.5 3.14 99.68
170 INT69569 Positive_regulation of Prnp 175 0.70 96.31 13.34 99.64
171 INT48853 Positive_regulation of BDNF 82 0.69 43.92 27.99 99.64
172 INT65502 Regulation of App 77 0.62 52.05 19.44 99.64
173 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 99.64
174 INT142112 Regulation of Regulation of App 3 0.39 2.46 0.59 99.64
175 INT7585 Regulation of Crh 24 0.58 9.88 12.97 99.62
176 INT185252 Gene_expression of Dlx2 7 0.71 8.8 6.24 99.60
177 INT133211 Gene_expression of Runx1 169 0.77 83.4 76.16 99.60
178 INT69572 Localization of Prnp 96 0.81 38.11 5.45 99.60
179 INT19511 Localization of Il6 212 0.81 118.17 67.67 99.60
180 INT99237 Gene_expression of Ntrk3 84 0.77 38.68 20.77 99.60
181 INT203490 Gene_expression of Runx3 19 0.76 27.56 12.57 99.60
182 INT86534 Positive_regulation of MAPK14 81 0.62 57.81 23.62 99.60
183 INT243418 Binding of Htt 14 0.30 5.94 0.44 99.60
184 INT249036 Gene_expression of Rnf103 1 0.78 7.53 2.42 99.60
185 INT235157 Gene_expression of Atxn2 3 0.68 6.74 1.23 99.60
186 INT127435 Gene_expression of Per1 89 0.77 13.94 22.31 99.60
187 INT72151 Phosphorylation of MYOT 2 0.01 1.49 0.88 99.60
188 INT161501 Binding of PC 20 0.47 5.74 0.72 99.60
189 INT275454 Positive_regulation of Atxn2 1 0.50 1.37 0.53 99.60
190 INT243417 Binding of Bri3 2 0.32 0.98 0.05 99.60
191 INT256109 Positive_regulation of Gene_expression of Sirt6 1 0.21 0.52 0.03 99.60
192 INT256123 Gene_expression of Sirt6 1 0.27 0.98 0.03 99.60
193 INT202434 Gene_expression of IGFBP6 3 0.53 1.52 0 99.60
194 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 99.58
195 INT132385 Gene_expression of Neurog2 12 0.73 7.03 3.44 99.58
196 INT193856 Localization of Psen1 19 0.73 9.79 0.41 99.58
197 INT197375 Gene_expression of Car1 84 0.65 16.46 16.45 99.58
198 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.58
199 INT203445 Gene_expression of Hes7 3 0.03 2.93 0.96 99.58
200 INT203502 Gene_expression of Neurog1 4 0.64 1.58 0.87 99.58
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