D:Neurogenic Diabetes Insipidus

Disease Term Synonyms Central Diabetes Insipidus, Diabetes Insipidus Central, DIABETES INSIPIDUS NEUROHYPOPHYSEAL, Diabetes Insipidus Pituitary, NEUROHYPOPHYSEAL DIABETES INSIPIDUS, Pituitary Diabetes Insipidus Documents 5 Hot Single Events 4 Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Neurogenic Diabetes Insipidus. They are ordered first by their relevance to Neurogenic Diabetes Insipidus and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Overall Pain Relevance	Term Relevance
1	INT106630	Binding of GRK5 and PRKCA	1	0.16	0.82	0.19	86.84
2	INT149473	Avp Positive_regulation of Localization of Pomc	4	0.48	2.64	0.56	5.00
3	INT354062	Avp Regulation of Lyz2	1	0.00	0.12	0.38	5.00
4	INT340177	Binding of Oxt and Avpr1a	6	0.15	2.24	0.29	5.00
5	INT340179	Binding of Oxt and Oxtr	10	0.31	2.53	0.19	5.00
6	INT354065	Pomc Regulation of Cort	1	0.07	1.69	0.12	5.00
7	INT354073	Oxt Positive_regulation of Localization of Avp	1	0.18	0.37	0.11	5.00
8	INT354070	Avpr1b Positive_regulation of Localization of Avp	1	0.43	0.06	0.1	5.00
9	INT354077	Avpr1b Positive_regulation of Localization of Gcg	1	0.12	0.05	0.1	5.00
10	INT354072	Cort Regulation of Pomc	1	0.07	1.22	0.08	5.00
11	INT354078	Avpr1b Positive_regulation of Localization of Pomc	1	0.28	2.71	0.08	5.00
12	INT354059	Negative_regulation of Pomc Regulation of Cort	1	0.12	0.74	0.03	5.00
13	INT354063	Binding of Oxt and Avpr1b	1	0.15	1.37	0.03	5.00
14	INT354064	Binding of Oxtr and Avpr1a	1	0.26	1.37	0.03	5.00
15	INT354068	Binding of Avpr1b and Avpr1a	1	0.29	1.36	0.03	5.00
16	INT354069	Oxt Positive_regulation of Localization of Pomc	1	0.11	0.88	0.03	5.00
17	INT354071	Pomc Positive_regulation of Localization of Cort	1	0.12	0.86	0.03	5.00
18	INT354075	Oxt Positive_regulation of Avpr1b	1	0.19	0.88	0.03	5.00
19	INT354081	Binding of Oxtr and Avpr1b	1	0.26	1.37	0.03	5.00
20	INT280828	Binding of Avp and Avpr2	2	0.15	0.28	0	5.00
21	INT340180	Binding of Avp and Oxt	3	0.17	0.57	0	5.00
22	INT354060	Avp Regulation of Avpr1b	1	0.23	0.36	0	5.00
23	INT354061	Binding of Avp and Oxtr	1	0.19	0.09	0	5.00
24	INT354074	Avpr1b Regulation of Localization of Pomc	1	0.16	1.44	0	5.00
25	INT354076	Binding of Avpr2 and Oxt	1	0.07	0.09	0	5.00
26	INT354079	Binding of Avpr2 and Oxtr	1	0.12	0.09	0	5.00
27	INT354080	Avpr2 Positive_regulation of Localization of Aqp2	1	0.02	0.07	0	5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Neurogenic Diabetes Insipidus. They are ordered first by their pain relevance and then by number of times they were reported in Neurogenic Diabetes Insipidus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Overall Pain Relevance	Term Relevance
1	INT72923	Positive_regulation of MCRS1	72	0.50	99.19	30.36	99.74
2	INT214	Localization of AVP	370	0.81	208.51	91.09	99.46
3	INT106636	Binding of PRKCA	7	0.28	3.06	1.93	86.84
4	INT106632	Binding of GRK5	1	0.31	0.82	0.19	86.84
5	INT15347	Positive_regulation of Localization of Pomc	81	0.70	28.1	31.01	79.80
6	INT1438	Localization of Pomc	360	0.81	101.26	116.47	79.48
7	INT118106	Binding of Avpr1b	3	0.35	3.83	1.48	72.88
8	INT695	Binding of POMC	304	0.48	56.66	126.85	70.84
9	INT175554	Binding of MCRS1	21	0.23	25.2	8.59	50.00
10	INT202981	Positive_regulation of Binding of MCRS1	3	0.18	4.05	1.02	50.00
11	INT316105	Binding of HIST1H4PS1	2	0.03	1.76	0.23	50.00
12	INT49191	Gene_expression of IFNAR1	14	0.41	9.96	3.84	26.12
13	INT106633	Positive_regulation of Gene_expression of IFNAR1	2	0.21	0	0.21	26.12
14	INT149467	Negative_regulation of Avpr1b	2	0.55	4.73	1.16	22.40
15	INT2640	Gene_expression of Pomc	424	0.78	120.72	155.37	5.68
16	INT6277	Positive_regulation of Gene_expression of Pomc	76	0.70	21.45	31.09	5.68
17	INT203	Positive_regulation of Pomc	257	0.70	90.56	92.84	5.12
18	INT2893	Localization of Oxt	219	0.80	28.96	79.43	5.00
19	INT3214	Localization of Ins1	527	0.80	196.9	79.26	5.00
20	INT462	Regulation of Pomc	157	0.62	41.67	67.27	5.00
21	INT1437	Negative_regulation of Pomc	132	0.59	35.22	60.97	5.00
22	INT927	Gene_expression of Oxt	184	0.78	44.71	35.79	5.00
23	INT3216	Positive_regulation of Localization of Ins1	170	0.69	56.78	35.63	5.00
24	INT7584	Gene_expression of Crh	112	0.78	39.15	25.33	5.00
25	INT11303	Gene_expression of Avp	116	0.78	39.23	23.88	5.00
26	INT18323	Negative_regulation of Localization of Ins1	122	0.58	45.74	23.04	5.00
27	INT8075	Localization of Crh	64	0.81	25.41	19.45	5.00
28	INT11628	Regulation of Localization of Pomc	44	0.61	10.46	18.66	5.00
29	INT21177	Positive_regulation of Crh	39	0.70	17.5	15.28	5.00
30	INT1436	Negative_regulation of Localization of Pomc	41	0.58	10.85	11.26	5.00
31	INT3546	Binding of Oxt	54	0.48	9.75	10.81	5.00
32	INT8740	Localization of Gcg	65	0.78	19	9.81	5.00
33	INT10879	Positive_regulation of Avp	39	0.65	14.01	8.76	5.00
34	INT168915	Gene_expression of Oxtr	49	0.75	20.53	7.22	5.00
35	INT19806	Regulation of Avp	29	0.53	14.17	6.94	5.00
36	INT40962	Localization of Avp	40	0.80	20.5	6.38	5.00
37	INT19777	Binding of Crh	16	0.40	6.65	4.36	5.00
38	INT114189	Positive_regulation of Cort	12	0.69	4.39	4.33	5.00
39	INT163878	Gene_expression of Npcd	14	0.05	3.35	4.29	5.00
40	INT8748	Positive_regulation of Localization of Gcg	24	0.67	9.74	3.46	5.00
41	INT118107	Positive_regulation of Avpr1b	4	0.66	6.89	2.99	5.00
42	INT11300	Positive_regulation of Gene_expression of Avp	24	0.50	10.18	2.69	5.00
43	INT53780	Binding of Avp	19	0.48	6.16	2.55	5.00
44	INT114188	Negative_regulation of Cort	7	0.41	3.69	2.53	5.00
45	INT168913	Negative_regulation of Avpr1a	7	0.43	5.88	2.47	5.00
46	INT168914	Gene_expression of Avpr1a	10	0.75	5.51	2.45	5.00
47	INT160326	Gene_expression of Cort	8	0.59	3.35	2.11	5.00
48	INT13294	Negative_regulation of Regulation of Pomc	5	0.38	2.83	2.01	5.00
49	INT139535	Gene_expression of Avpr1b	4	0.73	14.2	1.78	5.00
50	INT29084	Regulation of Localization of Crh	4	0.29	1.24	1.72	5.00
51	INT156213	Regulation of Cort	6	0.39	7.5	1.54	5.00
52	INT327376	Positive_regulation of Gene_expression of Oxtr	10	0.57	2.91	1.36	5.00
53	INT160327	Localization of Cort	3	0.70	7.18	1.34	5.00
54	INT131977	Positive_regulation of Localization of Avp	6	0.55	4.9	1.31	5.00
55	INT160329	Positive_regulation of Localization of Cort	2	0.60	4.08	0.79	5.00
56	INT72746	Localization of Avpr1a	4	0.73	2.54	0.73	5.00
57	INT354042	Transcription of Avpr1b	1	0.68	2.58	0.65	5.00
58	INT354046	Regulation of Avpr1b	1	0.58	3.96	0.63	5.00
59	INT354040	Localization of Avpr1b	1	0.76	3.65	0.58	5.00
60	INT265700	Regulation of Avpr1a	3	0.33	2.27	0.56	5.00
61	INT160330	Positive_regulation of Gene_expression of Cort	2	0.44	1.16	0.46	5.00
62	INT342278	Localization of Lyz2	2	0.03	0.37	0.37	5.00
63	INT354037	Gene_expression of Bglap-rs1	1	0.05	0.16	0.36	5.00
64	INT354045	Regulation of Gene_expression of Avpr1b	1	0.26	0.54	0.36	5.00
65	INT354049	Positive_regulation of Transcription of Avpr1b	1	0.47	0.45	0.16	5.00
66	INT354048	Localization of Npcd	1	0.01	0	0.15	5.00
67	INT354034	Regulation of Negative_regulation of Avpr1a	1	0.33	2.94	0.09	5.00
68	INT354043	Positive_regulation of Gene_expression of Avpr1b	1	0.41	0.72	0.08	5.00
69	INT354038	Negative_regulation of Regulation of Avpr1b	1	0.41	0.6	0.07	5.00
70	INT354036	Negative_regulation of Localization of Cort	1	0.18	0.74	0.03	5.00
71	INT174354	Gene_expression of Avpr2	8	0.35	0.87	0	5.00
72	INT280794	Localization of Aqp2	2	0.36	0.07	0	5.00
73	INT340164	Transcription of Avpr1a	2	0.40	0.17	0	5.00
74	INT354041	Regulation of Gene_expression of Avpr1a	1	0.46	2.25	0	5.00
75	INT354050	Localization of Oxtr	1	0.47	1.25	0	5.00