D:Neurogenic Diabetes Insipidus

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Disease Term
Synonyms Central Diabetes Insipidus, Diabetes Insipidus Central, DIABETES INSIPIDUS NEUROHYPOPHYSEAL, Diabetes Insipidus Pituitary, NEUROHYPOPHYSEAL DIABETES INSIPIDUS, Pituitary Diabetes Insipidus
Documents 5
Hot Single Events 4
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Neurogenic Diabetes Insipidus. They are ordered first by their relevance to Neurogenic Diabetes Insipidus and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT106630 Binding of GRK5 and PRKCA 1 0.16 0.82 0.19 86.84
2 INT149473 Avp Positive_regulation of Localization of Pomc 4 0.48 2.64 0.56 5.00
3 INT354062 Avp Regulation of Lyz2 1 0.00 0.12 0.38 5.00
4 INT340177 Binding of Oxt and Avpr1a 6 0.15 2.24 0.29 5.00
5 INT340179 Binding of Oxt and Oxtr 10 0.31 2.53 0.19 5.00
6 INT354065 Pomc Regulation of Cort 1 0.07 1.69 0.12 5.00
7 INT354073 Oxt Positive_regulation of Localization of Avp 1 0.18 0.37 0.11 5.00
8 INT354070 Avpr1b Positive_regulation of Localization of Avp 1 0.43 0.06 0.1 5.00
9 INT354077 Avpr1b Positive_regulation of Localization of Gcg 1 0.12 0.05 0.1 5.00
10 INT354072 Cort Regulation of Pomc 1 0.07 1.22 0.08 5.00
11 INT354078 Avpr1b Positive_regulation of Localization of Pomc 1 0.28 2.71 0.08 5.00
12 INT354059 Negative_regulation of Pomc Regulation of Cort 1 0.12 0.74 0.03 5.00
13 INT354063 Binding of Oxt and Avpr1b 1 0.15 1.37 0.03 5.00
14 INT354064 Binding of Oxtr and Avpr1a 1 0.26 1.37 0.03 5.00
15 INT354068 Binding of Avpr1b and Avpr1a 1 0.29 1.36 0.03 5.00
16 INT354069 Oxt Positive_regulation of Localization of Pomc 1 0.11 0.88 0.03 5.00
17 INT354071 Pomc Positive_regulation of Localization of Cort 1 0.12 0.86 0.03 5.00
18 INT354075 Oxt Positive_regulation of Avpr1b 1 0.19 0.88 0.03 5.00
19 INT354081 Binding of Oxtr and Avpr1b 1 0.26 1.37 0.03 5.00
20 INT280828 Binding of Avp and Avpr2 2 0.15 0.28 0 5.00
21 INT340180 Binding of Avp and Oxt 3 0.17 0.57 0 5.00
22 INT354060 Avp Regulation of Avpr1b 1 0.23 0.36 0 5.00
23 INT354061 Binding of Avp and Oxtr 1 0.19 0.09 0 5.00
24 INT354074 Avpr1b Regulation of Localization of Pomc 1 0.16 1.44 0 5.00
25 INT354076 Binding of Avpr2 and Oxt 1 0.07 0.09 0 5.00
26 INT354079 Binding of Avpr2 and Oxtr 1 0.12 0.09 0 5.00
27 INT354080 Avpr2 Positive_regulation of Localization of Aqp2 1 0.02 0.07 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Neurogenic Diabetes Insipidus. They are ordered first by their pain relevance and then by number of times they were reported in Neurogenic Diabetes Insipidus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT72923 Positive_regulation of MCRS1 72 0.50 99.19 30.36 99.74
2 INT214 Localization of AVP 370 0.81 208.51 91.09 99.46
3 INT106636 Binding of PRKCA 7 0.28 3.06 1.93 86.84
4 INT106632 Binding of GRK5 1 0.31 0.82 0.19 86.84
5 INT15347 Positive_regulation of Localization of Pomc 81 0.70 28.1 31.01 79.80
6 INT1438 Localization of Pomc 360 0.81 101.26 116.47 79.48
7 INT118106 Binding of Avpr1b 3 0.35 3.83 1.48 72.88
8 INT695 Binding of POMC 304 0.48 56.66 126.85 70.84
9 INT175554 Binding of MCRS1 21 0.23 25.2 8.59 50.00
10 INT202981 Positive_regulation of Binding of MCRS1 3 0.18 4.05 1.02 50.00
11 INT316105 Binding of HIST1H4PS1 2 0.03 1.76 0.23 50.00
12 INT49191 Gene_expression of IFNAR1 14 0.41 9.96 3.84 26.12
13 INT106633 Positive_regulation of Gene_expression of IFNAR1 2 0.21 0 0.21 26.12
14 INT149467 Negative_regulation of Avpr1b 2 0.55 4.73 1.16 22.40
15 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 5.68
16 INT6277 Positive_regulation of Gene_expression of Pomc 76 0.70 21.45 31.09 5.68
17 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84 5.12
18 INT2893 Localization of Oxt 219 0.80 28.96 79.43 5.00
19 INT3214 Localization of Ins1 527 0.80 196.9 79.26 5.00
20 INT462 Regulation of Pomc 157 0.62 41.67 67.27 5.00
21 INT1437 Negative_regulation of Pomc 132 0.59 35.22 60.97 5.00
22 INT927 Gene_expression of Oxt 184 0.78 44.71 35.79 5.00
23 INT3216 Positive_regulation of Localization of Ins1 170 0.69 56.78 35.63 5.00
24 INT7584 Gene_expression of Crh 112 0.78 39.15 25.33 5.00
25 INT11303 Gene_expression of Avp 116 0.78 39.23 23.88 5.00
26 INT18323 Negative_regulation of Localization of Ins1 122 0.58 45.74 23.04 5.00
27 INT8075 Localization of Crh 64 0.81 25.41 19.45 5.00
28 INT11628 Regulation of Localization of Pomc 44 0.61 10.46 18.66 5.00
29 INT21177 Positive_regulation of Crh 39 0.70 17.5 15.28 5.00
30 INT1436 Negative_regulation of Localization of Pomc 41 0.58 10.85 11.26 5.00
31 INT3546 Binding of Oxt 54 0.48 9.75 10.81 5.00
32 INT8740 Localization of Gcg 65 0.78 19 9.81 5.00
33 INT10879 Positive_regulation of Avp 39 0.65 14.01 8.76 5.00
34 INT168915 Gene_expression of Oxtr 49 0.75 20.53 7.22 5.00
35 INT19806 Regulation of Avp 29 0.53 14.17 6.94 5.00
36 INT40962 Localization of Avp 40 0.80 20.5 6.38 5.00
37 INT19777 Binding of Crh 16 0.40 6.65 4.36 5.00
38 INT114189 Positive_regulation of Cort 12 0.69 4.39 4.33 5.00
39 INT163878 Gene_expression of Npcd 14 0.05 3.35 4.29 5.00
40 INT8748 Positive_regulation of Localization of Gcg 24 0.67 9.74 3.46 5.00
41 INT118107 Positive_regulation of Avpr1b 4 0.66 6.89 2.99 5.00
42 INT11300 Positive_regulation of Gene_expression of Avp 24 0.50 10.18 2.69 5.00
43 INT53780 Binding of Avp 19 0.48 6.16 2.55 5.00
44 INT114188 Negative_regulation of Cort 7 0.41 3.69 2.53 5.00
45 INT168913 Negative_regulation of Avpr1a 7 0.43 5.88 2.47 5.00
46 INT168914 Gene_expression of Avpr1a 10 0.75 5.51 2.45 5.00
47 INT160326 Gene_expression of Cort 8 0.59 3.35 2.11 5.00
48 INT13294 Negative_regulation of Regulation of Pomc 5 0.38 2.83 2.01 5.00
49 INT139535 Gene_expression of Avpr1b 4 0.73 14.2 1.78 5.00
50 INT29084 Regulation of Localization of Crh 4 0.29 1.24 1.72 5.00
51 INT156213 Regulation of Cort 6 0.39 7.5 1.54 5.00
52 INT327376 Positive_regulation of Gene_expression of Oxtr 10 0.57 2.91 1.36 5.00
53 INT160327 Localization of Cort 3 0.70 7.18 1.34 5.00
54 INT131977 Positive_regulation of Localization of Avp 6 0.55 4.9 1.31 5.00
55 INT160329 Positive_regulation of Localization of Cort 2 0.60 4.08 0.79 5.00
56 INT72746 Localization of Avpr1a 4 0.73 2.54 0.73 5.00
57 INT354042 Transcription of Avpr1b 1 0.68 2.58 0.65 5.00
58 INT354046 Regulation of Avpr1b 1 0.58 3.96 0.63 5.00
59 INT354040 Localization of Avpr1b 1 0.76 3.65 0.58 5.00
60 INT265700 Regulation of Avpr1a 3 0.33 2.27 0.56 5.00
61 INT160330 Positive_regulation of Gene_expression of Cort 2 0.44 1.16 0.46 5.00
62 INT342278 Localization of Lyz2 2 0.03 0.37 0.37 5.00
63 INT354037 Gene_expression of Bglap-rs1 1 0.05 0.16 0.36 5.00
64 INT354045 Regulation of Gene_expression of Avpr1b 1 0.26 0.54 0.36 5.00
65 INT354049 Positive_regulation of Transcription of Avpr1b 1 0.47 0.45 0.16 5.00
66 INT354048 Localization of Npcd 1 0.01 0 0.15 5.00
67 INT354034 Regulation of Negative_regulation of Avpr1a 1 0.33 2.94 0.09 5.00
68 INT354043 Positive_regulation of Gene_expression of Avpr1b 1 0.41 0.72 0.08 5.00
69 INT354038 Negative_regulation of Regulation of Avpr1b 1 0.41 0.6 0.07 5.00
70 INT354036 Negative_regulation of Localization of Cort 1 0.18 0.74 0.03 5.00
71 INT174354 Gene_expression of Avpr2 8 0.35 0.87 0 5.00
72 INT280794 Localization of Aqp2 2 0.36 0.07 0 5.00
73 INT340164 Transcription of Avpr1a 2 0.40 0.17 0 5.00
74 INT354041 Regulation of Gene_expression of Avpr1a 1 0.46 2.25 0 5.00
75 INT354050 Localization of Oxtr 1 0.47 1.25 0 5.00
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