D:Neurologic Gait Disorders

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Disease Term
Synonyms AMBULATION DISORDER NEUROLOGIC, Ambulation Disorders Neurologic, Athetotic Gait, Broadened Gait, Charcot Gait, Charcot Gaits, Charcot S Gait, Charcots Gait, Drop Foot Gait, DUCK GAIT, Festinating Gait
Documents 133
Hot Single Events 22
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Neurologic Gait Disorders. They are ordered first by their relevance to Neurologic Gait Disorders and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT297613 Negative_regulation of ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.66 0 82.32
2 INT297614 ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.56 0 78.72
3 INT111802 Binding of CD40LG and TFPI 1 0.14 0.62 0.16 71.00
4 INT326585 Binding of GYPA and SLC6A3 1 0.13 0.86 2.64 5.00
5 INT326586 SLC18A2 Negative_regulation of DDC 1 0.28 0.91 0.66 5.00
6 INT183387 Il6 Positive_regulation of Gene_expression of Il10 2 0.19 1.8 0.63 5.00
7 INT317427 IFN1@ Positive_regulation of ISYNA1 1 0.12 0.49 0.45 5.00
8 INT326587 GYPA Regulation of DDC 1 0.08 0.83 0.33 5.00
9 INT333763 Il27 Positive_regulation of Gene_expression of Il10 2 0.22 0.8 0.26 5.00
10 INT333762 Positive_regulation of thd Positive_regulation of Eae1 1 0.00 1.6 0.22 5.00
11 INT333758 Hand1 Positive_regulation of Eae1 1 0.05 1.6 0.22 5.00
12 INT326583 GYPA Negative_regulation of Binding of GYPA and SLC6A3 1 0.03 0.22 0.22 5.00
13 INT333760 thd Positive_regulation of Eae1 1 0.00 1.6 0.22 5.00
14 INT340744 CSF2 Regulation of BDNF 1 0.13 1.45 0.14 5.00
15 INT340742 Positive_regulation of CSF2 Regulation of BDNF 1 0.22 1.46 0.14 5.00
16 INT333761 Il27 Positive_regulation of Il10 1 0.16 0.58 0.13 5.00
17 INT333764 Il6 Regulation of Gene_expression of Il6ra 1 0.02 0.52 0.12 5.00
18 INT333765 Positive_regulation of Vdr Regulation of Gene_expression of Ccr6 1 0.21 0.48 0.12 5.00
19 INT333759 Il6 Positive_regulation of Il27 1 0.09 0.68 0.12 5.00
20 INT320659 Vsig2 Positive_regulation of Transcription of Nos2 1 0.07 0.65 0.07 5.00
21 INT268679 Binding of HDAC1 and NCOR2 3 0.17 2.8 0.07 5.00
22 INT317426 Binding of CSF2 and PML 1 0.08 1.25 0.06 5.00
23 INT284916 IL1RN Negative_regulation of HDAC4 1 0.00 1.66 0.03 5.00
24 INT345350 Casp3 Positive_regulation of Prkcd 1 0.05 0.79 0.03 5.00
25 INT284919 XRCC6 Negative_regulation of BAX 1 0.01 0.64 0 5.00
26 INT284920 Binding of HDAC1 and NCOR1 1 0.03 0.13 0 5.00
27 INT284918 RUNX1T1 Regulation of DNMT1 1 0.21 1.09 0 5.00
28 INT284917 RUNX1T1 Regulation of HDAC9 1 0.19 1.09 0 5.00
29 INT284914 Binding of HDAC1 and NCK1 1 0.00 0.13 0 5.00
30 INT340743 Negative_regulation of CSF2 Positive_regulation of ZNF807 1 0.00 1.77 0 5.00
31 INT340745 CSF2 Positive_regulation of ZNF807 1 0.00 1.76 0 5.00
32 INT297615 Binding of TSC1 and HDAC9 1 0.01 0.4 0 5.00
33 INT308854 Bcl2a1a Positive_regulation of Gene_expression of HTT 1 0.14 0 0 5.00
34 INT284915 Binding of CDKN2B and HIST2H3C 1 0.05 0.43 0 5.00
35 INT284995 Binding of HDAC1 and Sin3a 1 0.00 0.13 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Neurologic Gait Disorders. They are ordered first by their pain relevance and then by number of times they were reported in Neurologic Gait Disorders. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT265995 Transcription of IGKV2-29 1 0.12 0.28 0 97.68
2 INT297626 Gene_expression of RLN3 3 0.11 5.07 0.3 94.92
3 INT297627 Positive_regulation of Gene_expression of RLN3 3 0.08 3.06 0.08 94.92
4 INT200738 Gene_expression of HIST2H4A 7 0.18 4.65 0.91 94.80
5 INT265661 Positive_regulation of Gene_expression of HIST2H4A 2 0.09 2.69 0.28 94.80
6 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3 94.16
7 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69 94.16
8 INT137767 Gene_expression of Eae1 74 0.34 89.32 20.48 91.60
9 INT38671 Positive_regulation of KRT20 62 0.53 40.17 5.6 90.76
10 INT24740 Positive_regulation of Cd79a 36 0.48 14.71 2.17 90.76
11 INT38674 Regulation of KRT20 32 0.44 19 2.15 90.76
12 INT61148 Regulation of Cd79a 13 0.51 6.95 1.9 90.76
13 INT8670 Negative_regulation of Afp 27 0.58 19.85 2.87 89.84
14 INT16245 Binding of Spn 4 0.31 3.83 0.45 89.20
15 INT169568 Binding of Fcer2 3 0.06 2.12 0.33 89.20
16 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9 88.92
17 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 87.56
18 INT37193 Negative_regulation of BDNF-AS 21 0.37 15.06 3.12 85.68
19 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 85.52
20 INT8669 Positive_regulation of Afp 66 0.70 58.21 7.67 83.16
21 INT297628 Negative_regulation of ZNF275 1 0.00 3.2 0 82.32
22 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 81.60
23 INT108710 Gene_expression of HAL 36 0.58 14.75 2.16 78.48
24 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 77.24
25 INT98239 Negative_regulation of Htt 13 0.43 7.84 0.6 77.04
26 INT18684 Localization of Cm3 2 0.61 1.69 0.07 76.76
27 INT193452 Negative_regulation of Ndufaf1 11 0.06 10.32 1.23 71.68
28 INT24816 Binding of CD40LG 68 0.47 45.48 11.56 71.00
29 INT25 Positive_regulation of LAMC2 19 0.67 8.64 7.06 67.48
30 INT24889 Negative_regulation of CABIN1 36 0.48 16.76 4.73 66.32
31 INT118343 Positive_regulation of Eae1 121 0.39 136.06 34.87 66.16
32 INT77281 Negative_regulation of HIVEP1 132 0.49 102.78 5.36 65.28
33 INT27554 Regulation of Eln 6 0.52 6.76 0.39 63.88
34 INT6623 Gene_expression of NA 231 0.78 45.78 59.36 63.84
35 INT14091 Binding of Vsig2 8 0.42 3.21 3.91 60.64
36 INT170455 Gene_expression of Atp8a1 66 0.75 24.63 3.94 55.32
37 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 53.36
38 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54 53.12
39 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 52.72
40 INT17275 Gene_expression of HIVEP1 267 0.75 232.07 24.06 52.72
41 INT59454 Regulation of Gene_expression of CSF2 22 0.52 19.67 2.69 52.72
42 INT86998 Regulation of HIVEP1 49 0.44 37.83 4 51.84
43 INT93360 Gene_expression of Slc6a3 63 0.78 19.54 26.55 50.96
44 INT125836 Gene_expression of Slc18a2 8 0.72 2.65 4.03 50.96
45 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 50.72
46 INT541 Positive_regulation of MBP 31 0.67 28.56 12.24 50.64
47 INT90639 Positive_regulation of Slc6a3 25 0.61 10.95 10.41 50.36
48 INT137262 Positive_regulation of Slc18a2 5 0.68 1.45 3.1 50.36
49 INT315626 Localization of DLEU1 2 0.35 4.17 0.07 50.32
50 INT161575 Localization of CACNA1A 4 0.75 5.28 2.26 50.20
51 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 49.60
52 INT74143 Positive_regulation of Positive_regulation of Atm 1 0.31 0.79 0.15 49.60
53 INT23072 Positive_regulation of Atm 2 0.40 1.76 0.24 49.04
54 INT301479 Positive_regulation of Gene_expression of Vsig2 2 0.32 2.78 0.08 46.60
55 INT92632 Gene_expression of Vsig2 48 0.50 19.93 3.04 46.12
56 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53 45.96
57 INT67097 Gene_expression of MIB1 20 0.75 21.06 1.03 44.48
58 INT345348 Positive_regulation of Gene_expression of Slc18a2 1 0.28 0.41 0.27 41.88
59 INT9900 Positive_regulation of Vwf 80 0.69 51.85 18.13 40.48
60 INT211306 Localization of Trav6-3 6 0.21 1.79 0.43 38.92
61 INT2921 Positive_regulation of F8 53 0.59 41.56 8.56 38.76
62 INT10889 Gene_expression of F8 60 0.78 41.36 5.06 38.76
63 INT17741 Gene_expression of MBP 67 0.78 23.67 9.65 31.52
64 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 30.56
65 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 28.36
66 INT274683 Localization of HIST2H4A 5 0.12 1.54 0 26.40
67 INT297624 Localization of RLN3 1 0.05 1 0 26.40
68 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 26.28
69 INT16624 Localization of Grin1 38 0.79 8.46 17.15 24.92
70 INT308845 Gene_expression of Nisch 1 0.10 3.32 1.92 24.80
71 INT284992 Negative_regulation of HDAC8 1 0.21 2.36 0.04 23.76
72 INT284958 Negative_regulation of HDAC6 1 0.25 1.56 0.04 18.56
73 INT177842 Negative_regulation of HDAC1 6 0.31 4.65 0.49 14.96
74 INT284973 Negative_regulation of Negative_regulation of HDAC1 1 0.20 1.59 0.04 14.96
75 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06 12.92
76 INT155944 Gene_expression of Foxp3 66 0.66 24.37 9.12 12.92
77 INT30961 Binding of HTR2A 33 0.47 11.44 12.86 11.04
78 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 8.48
79 INT216380 Gene_expression of PAX6 49 0.78 15.63 1.22 5.36
80 INT214 Localization of AVP 370 0.81 208.51 91.09 5.24
81 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
82 INT767 Localization of Gnrhr 565 0.80 106.68 214.57 5.00
83 INT4740 Gene_expression of Th 298 0.78 61.27 154.03 5.00
84 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61 5.00
85 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 5.00
86 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38 5.00
87 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 5.00
88 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
89 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
90 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 5.00
91 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 5.00
92 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 5.00
93 INT14049 Positive_regulation of GRIN1 102 0.70 48.31 71.06 5.00
94 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 5.00
95 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 5.00
96 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 5.00
97 INT11807 Gene_expression of Il2 266 0.78 112 64.97 5.00
98 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
99 INT6894 Gene_expression of CNR1 168 0.78 74.07 62.84 5.00
100 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
101 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69 5.00
102 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53 5.00
103 INT4957 Negative_regulation of Grin1 87 0.59 24.51 53.21 5.00
104 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 5.00
105 INT57021 Positive_regulation of Gene_expression of Grin1 62 0.70 24.77 47.31 5.00
106 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 5.00
107 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07 5.00
108 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65 5.00
109 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
110 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24 5.00
111 INT12608 Regulation of CNR1 62 0.60 24.36 36.02 5.00
112 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 5.00
113 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23 5.00
114 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 5.00
115 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
116 INT57024 Regulation of Gene_expression of Grin1 32 0.62 9.77 32.6 5.00
117 INT145594 Gene_expression of Mtx1 64 0.57 35.33 30.35 5.00
118 INT90792 Localization of Il10 144 0.80 87.88 30.03 5.00
119 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
120 INT48853 Positive_regulation of BDNF 82 0.69 43.92 27.99 5.00
121 INT14690 Localization of CSF2 124 0.80 85.17 27.26 5.00
122 INT135411 Gene_expression of Il23a 76 0.72 72.87 26.15 5.00
123 INT76095 Positive_regulation of ISYNA1 117 0.55 79.73 25.86 5.00
124 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 5.00
125 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 5.00
126 INT102112 Gene_expression of Prnp 440 0.78 209.32 22.5 5.00
127 INT96156 Gene_expression of Cd40 144 0.77 56.95 21.7 5.00
128 INT11804 Positive_regulation of Gene_expression of Il2 70 0.70 33 21.63 5.00
129 INT14700 Regulation of IFNA1 111 0.45 66.16 21.52 5.00
130 INT5916 Positive_regulation of HTR1A 51 0.67 18.27 21.38 5.00
131 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 5.00
132 INT49774 Binding of DRD2 48 0.48 17.42 20.73 5.00
133 INT86751 Negative_regulation of Il10 62 0.59 40.1 20.51 5.00
134 INT66281 Transcription of Nos2 81 0.71 39.49 20.37 5.00
135 INT23533 Gene_expression of CA2 110 0.75 30.81 19.4 5.00
136 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 5.00
137 INT96155 Gene_expression of Cd86 134 0.77 50.56 17.13 5.00
138 INT94467 Positive_regulation of Hand1 71 0.58 59 16.96 5.00
139 INT21532 Negative_regulation of Gene_expression of Il2 47 0.59 20.43 16.96 5.00
140 INT93948 Negative_regulation of Gene_expression of Il12a 48 0.55 27.77 16.87 5.00
141 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 5.00
142 INT6480 Positive_regulation of IL1RN 59 0.69 33.7 16.66 5.00
143 INT6129 Positive_regulation of Localization of AVP 63 0.70 30.44 16.64 5.00
144 INT103757 Negative_regulation of Il12a 37 0.55 21.62 16.38 5.00
145 INT170754 Localization of IFN1@ 121 0.78 66.78 15.6 5.00
146 INT71634 Gene_expression of SLC6A3 45 0.78 13.48 15.23 5.00
147 INT3545 Positive_regulation of Mtx1 27 0.42 11.97 14.83 5.00
148 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74 5.00
149 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 5.00
150 INT70265 Regulation of MRI1 42 0.39 30.95 14.18 5.00
151 INT132335 Gene_expression of KCNA1 36 0.77 18.31 13.36 5.00
152 INT20381 Localization of Il2 71 0.77 34.23 13.03 5.00
153 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 5.00
154 INT49975 Binding of SLC6A3 34 0.47 9.86 12.41 5.00
155 INT112003 Localization of ROS1 94 0.73 66.32 12.16 5.00
156 INT36287 Binding of CD4 96 0.47 58.93 11.88 5.00
157 INT661 Gene_expression of REN 100 0.78 48.21 11.36 5.00
158 INT63773 Gene_expression of DRD2 25 0.78 10.41 10.8 5.00
159 INT71633 Negative_regulation of SLC6A3 25 0.59 10.5 10.69 5.00
160 INT71769 Negative_regulation of Gene_expression of Il10 40 0.57 22.53 10.37 5.00
161 INT19132 Gene_expression of CYP27A1 83 0.75 34.31 10.17 5.00
162 INT67048 Gene_expression of ITGA4 58 0.75 28.93 10.16 5.00
163 INT115046 Gene_expression of Crem 68 0.77 27.24 10.01 5.00
164 INT140338 Negative_regulation of Gene_expression of Il17a 34 0.46 23.82 9.87 5.00
165 INT6065 Localization of GRIN1 15 0.74 3.15 9.81 5.00
166 INT96157 Gene_expression of Cd80 74 0.77 31.19 9.78 5.00
167 INT181344 Gene_expression of Ccr6 28 0.61 24.34 9.78 5.00
168 INT170333 Binding of IFN1@ 68 0.47 49.01 9.72 5.00
169 INT53062 Gene_expression of Ddc 31 0.77 11.59 9.63 5.00
170 INT181405 Gene_expression of Ccl20 26 0.65 23.02 9.46 5.00
171 INT14301 Binding of CSF2 82 0.48 67.95 8.98 5.00
172 INT108931 Negative_regulation of BDNF 38 0.59 19.61 8.84 5.00
173 INT34372 Gene_expression of Cfp 102 0.67 37.66 8.72 5.00
174 INT18391 Positive_regulation of GYPA 41 0.40 16.47 8.69 5.00
175 INT44550 Positive_regulation of Gene_expression of AVP 38 0.70 22.27 8.62 5.00
176 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57 5.00
177 INT154094 Negative_regulation of Eae1 25 0.18 30.42 7.89 5.00
178 INT175526 Phosphorylation of Gopc 73 0.53 21.08 7.86 5.00
179 INT177759 Negative_regulation of IFN1@ 51 0.57 31.81 7.76 5.00
180 INT160440 Positive_regulation of Crem 48 0.69 20.38 7.66 5.00
181 INT18190 Regulation of DRD2 11 0.60 9.01 7.63 5.00
182 INT18524 Regulation of Gene_expression of IFNA1 37 0.44 18.79 7.62 5.00
183 INT131359 Positive_regulation of Gene_expression of Cd4 40 0.58 22.43 7.53 5.00
184 INT70814 Negative_regulation of Il2 40 0.56 13.36 7.22 5.00
185 INT138922 Positive_regulation of Stat1 57 0.69 28.35 7.2 5.00
186 INT228659 Phosphorylation of Eif4ebp1 10 0.80 27.53 6.87 5.00
187 INT90461 Negative_regulation of DRD2 21 0.53 8.35 6.55 5.00
188 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41 5.00
189 INT192225 Gene_expression of HDAC9 35 0.58 32.82 6.36 5.00
190 INT57256 Gene_expression of HLA-DQA2 52 0.55 23.87 6.27 5.00
191 INT34370 Positive_regulation of Cfp 26 0.46 15.21 6.12 5.00
192 INT22128 Positive_regulation of HIVEP1 61 0.43 70.52 6.07 5.00
193 INT122653 Positive_regulation of Gene_expression of CD4 48 0.68 22.5 5.96 5.00
194 INT103880 Positive_regulation of DRD2 9 0.67 5.57 5.93 5.00
195 INT138915 Gene_expression of Stat1 144 0.77 69.53 5.85 5.00
196 INT188844 Gene_expression of AES 44 0.58 33.94 5.85 5.00
197 INT10980 Gene_expression of GYPA 40 0.78 15.32 5.51 5.00
198 INT125066 Negative_regulation of HDAC4 56 0.49 41.55 5.42 5.00
199 INT60585 Regulation of TP53 59 0.59 54.55 5.21 5.00
200 INT11805 Regulation of Gene_expression of Il2 19 0.62 6.62 5.2 5.00
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