D:Neuromyelitis Optica

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Disease Term
Synonyms Devic Disease, DEVIC S DISEASE, Devic S Syndrome, Devic S Syndromes, DEVIC SYNDROME, Devics Disease, DEVICS SYNDROME, Disease Devic, Disease Devic S, Syndrome Devic, Syndrome Devic S
Documents 227
Hot Single Events 200
Hot Interactions 56

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Neuromyelitis Optica. They are ordered first by their relevance to Neuromyelitis Optica and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT206764 Binding of AQP4 and Nqo1 8 0.05 13.45 2.84 100.00
2 INT140172 Binding of Nqo1 and IgG 5 0.17 6.68 1.2 100.00
3 INT235975 Binding of AQP4 and IgG 2 0.04 4.11 0.53 100.00
4 INT169648 IGHG3 Regulation of AQP4 3 0.02 4.63 0.55 100.00
5 INT235956 Binding of Aqp4 and NMO-IgG 1 0.04 4.53 0.5 100.00
6 INT161166 Binding of Aqp4 and Igh-6 1 0.03 2.58 0.49 100.00
7 INT308701 Binding of AQP4 and DDX41 1 0.15 3.53 0.32 100.00
8 INT308708 DDX41 Regulation of AQP4 1 0.10 2.79 0.26 100.00
9 INT235971 Positive_regulation of Binding of Nqo1 and NMO-IgG 1 0.00 1.86 0.32 100.00
10 INT235969 Binding of Ighg1 and Nqo1 1 0.01 2.63 0.04 100.00
11 INT332581 Binding of Nqo1 and MRI1 1 0.01 1.68 0.12 100.00
12 INT235968 NMO-IgG Positive_regulation of Nqo1 1 0.00 2.11 0.03 100.00
13 INT250243 FCGR3A Regulation of Gene_expression of SLC1A2 1 0.00 0.78 0.06 100.00
14 INT235958 Binding of Ighg1 and Aqp4 1 0.14 1.32 0.3 100.00
15 INT235977 Binding of AQP4 and Ighg1 1 0.03 1.31 0.3 100.00
16 INT206763 Binding of CSF2 and Nqo1 1 0.00 1.7 0.25 100.00
17 INT235959 Nqo1 Positive_regulation of Localization of Aqp4 1 0.02 1.39 0.26 100.00
18 INT327789 Binding of IgG and Alms1 1 0.01 1.1 0.17 100.00
19 INT327790 Binding of Nqo1 and Alms1 1 0.00 1.1 0.17 100.00
20 INT327791 Binding of AQP4 and Alms1 1 0.03 1.1 0.17 100.00
21 INT235967 Binding of Ighm and Nqo1 1 0.00 1.45 0.23 100.00
22 INT235961 Binding of Nqo1 and Aqp4 1 0.02 0.9 0.14 100.00
23 INT273047 Binding of Aqp4 and Sct 1 0.04 1.41 0 100.00
24 INT250247 FCGR3A Negative_regulation of AQP4 1 0.01 0.87 0.62 99.84
25 INT250253 Binding of AQP4 and SLC1A2 1 0.30 2.95 1.09 99.16
26 INT308704 Binding of DDX41 and M1 1 0.02 2.09 0.1 98.96
27 INT308709 Positive_regulation of Binding of AQP4 and DDX41 1 0.18 1.19 0.14 98.92
28 INT96590 Mog Regulation of S100B 1 0.32 0.97 0.13 98.68
29 INT96589 Mbp Regulation of S100B 1 0.34 0.97 0.13 98.68
30 INT334153 Binding of AQP4 and CSF2 1 0.16 3 0.75 98.08
31 INT250250 Gene_expression of AQP4 Positive_regulation of Gene_expression of SLC1A2 1 0.37 1.1 0.39 96.70
32 INT279964 STAT3 Regulation of Transcription of FGG 1 0.22 1.37 0.2 95.60
33 INT250248 Binding of AQP4 and SLC1A3 1 0.11 1.55 0.77 95.44
34 INT250251 Binding of SLC1A2 and SLC1A3 1 0.09 1.12 0.43 95.44
35 INT250249 Binding of SLC1A2 and Positive_regulation of SLC1A3 1 0.12 0.69 0.08 95.44
36 INT250244 Binding of AQP4 and Positive_regulation of SLC1A3 1 0.14 0.69 0.08 95.44
37 INT308703 Positive_regulation of Binding of AQP4 and M1 1 0.08 0.61 0 95.44
38 INT308706 Binding of AQP4 and M1 1 0.06 0.86 0 94.92
39 INT247851 Negative_regulation of Aqp4 Negative_regulation of Positive_regulation of Narfl 1 0.09 1.78 0.15 94.16
40 INT279965 STAT3 Regulation of Transcription of BCL2L1 1 0.10 2.31 0.19 91.28
41 INT331563 Binding of Cd4 and Apcs 1 0.17 0.36 0 91.08
42 INT279961 CSF2 Negative_regulation of TTR 1 0.04 1.07 0.23 90.88
43 INT339967 Binding of Mog and Eae1 1 0.02 1.67 0.6 90.24
44 INT350698 Mir326 Regulation of Ets1 1 0.01 1.27 0.4 89.60
45 INT279962 Binding of A1BG and BCL2L1 1 0.13 1.11 0.1 88.52
46 INT308707 Binding of AQP4 and IGHG3 1 0.01 0.88 0 87.52
47 INT235964 Binding of Atp9a and Aqp4 1 0.01 0.55 0.08 87.36
48 INT250252 Binding of SLC1A2 and GOPC 1 0.05 0.44 0.35 87.16
49 INT318028 Binding of IRF6 and Tlr4 1 0.00 0.61 0.06 86.64
50 INT250254 Binding of SLC1A3 and GOPC 1 0.02 0.44 0.35 86.56
51 INT250242 Binding of AQP4 and GOPC 1 0.06 0.39 0.35 85.92
52 INT235957 Binding of Mog and Bcr 1 0.02 1.13 0.29 84.40
53 INT235966 Binding of Mog and Trav6-3 1 0.01 1.07 0.29 84.40
54 INT235962 Binding of Bcr and Trav6-3 1 0.00 1.12 0.29 83.76
55 INT350693 Mir326 Positive_regulation of Regulation of thd 1 0.00 1.32 0.41 83.68
56 INT235963 Snta1 Regulation of Gene_expression of Aqp4 1 0.41 0.23 0.05 80.64
57 INT157343 Binding of AQP4 and HLA-DPB1 1 0.30 0.89 0.43 78.60
58 INT235974 Negative_regulation of Binding of APC and Trav6-3 1 0.00 1.15 0.24 78.52
59 INT235972 Negative_regulation of Binding of APC and Bcr 1 0.01 1.15 0.24 78.52
60 INT347722 Binding of Aqp4 and Nidds 1 0.31 0.32 0 78.40
61 INT235976 Binding of APC and Trav6-3 2 0.01 2.62 0.24 77.96
62 INT250246 SLC1A2 Positive_regulation of AQP4 1 0.13 0.22 0.16 77.76
63 INT235973 Binding of APC and Bcr 1 0.01 1.14 0.24 77.64
64 INT250241 SLC1A3 Positive_regulation of AQP4 1 0.13 0.21 0.16 77.32
65 INT235960 Binding of Aqp4 and H47 1 0.01 0.13 0 73.44
66 INT181444 Ccl5 Positive_regulation of Csf2 1 0.07 1.88 0.45 72.80
67 INT181447 Ccl3 Positive_regulation of Csf2 1 0.06 1.89 0.45 72.80
68 INT250245 Binding of FCGR3A and SLC1A3 1 0.00 0.18 0.05 68.64
69 INT181443 Csf2 Positive_regulation of Cxcl10 1 0.02 1.69 0.39 63.52
70 INT181441 Csf2 Positive_regulation of Cxcl12 1 0.02 1.69 0.39 63.52
71 INT181439 Csf2 Positive_regulation of Ccl19 1 0.06 1.68 0.38 63.52
72 INT274449 Binding of Cd4 and H2 2 0.05 1.25 0.1 59.00
73 INT147068 Binding of Aqp4 and Tg(CAG-EGFP)D4Nagy 1 0.06 0 0 50.00
74 INT147065 IgG Regulation of Gene_expression of Aqp4 1 0.37 0 0 50.00
75 INT147062 LAMC2 Negative_regulation of CD40LG 1 0.47 0 0 50.00
76 INT147066 Binding of Aqp4 and IgG 1 0.40 0 0 50.00
77 INT147067 Binding of Aqp4 and Nqo1 1 0.04 0 0 50.00
78 INT190751 Adcyap1 Positive_regulation of Vipr2 2 0.16 1.02 0.36 49.88
79 INT273048 Adcyap1 Positive_regulation of Adcyap1r1 1 0.11 1.02 0.19 49.88
80 INT181437 Binding of Ccr7 and Ccl21b 1 0.01 2.23 0.87 43.64
81 INT181452 Binding of Ccl19 and Ccl21b 1 0.02 2.22 0.86 43.24
82 INT273046 Vip Negative_regulation of Gene_expression of Adcyap1 1 0.20 1.14 0.21 38.84
83 INT308702 Binding of AQP4 and CD40LG 1 0.10 0 0 34.80
84 INT247843 Narfl Regulation of Aqp4 1 0.04 1.07 0.04 30.32
85 INT247855 Positive_regulation of Narfl Regulation of Aqp4 1 0.04 2.93 0.04 30.32
86 INT273040 Vip Regulation of Bax 1 0.23 1.69 0.13 21.12
87 INT273041 Adcyap1 Regulation of Bax 1 0.21 1.69 0.13 20.80
88 INT122567 Mog Positive_regulation of Eae1 8 0.31 10.18 4.26 5.00
89 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66 5.00
90 INT181436 Binding of Ccl2 and Eae1 1 0.05 5.14 1.27 5.00
91 INT181434 Binding of Ccr2 and Ccl2 1 0.27 6.06 1.04 5.00
92 INT154778 Cldn11 Positive_regulation of Eae1 4 0.12 3.24 1.03 5.00
93 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03 5.00
94 INT329120 Binding of KCNA1 and CNTNAP2 1 0.09 1.23 0.75 5.00
95 INT329119 Binding of CNTN2 and CNTNAP2 1 0.08 2.41 0.73 5.00
96 INT350699 Binding of Casp8 and Stat3 1 0.04 1.81 0.58 5.00
97 INT350716 Binding of CD58 and Casp8 1 0.03 1.81 0.58 5.00
98 INT329116 Binding of LGI1 and CNTNAP2 1 0.38 1.3 0.44 5.00
99 INT329122 Binding of KCNA1 and LGI1 1 0.08 0.29 0.43 5.00
100 INT181448 Eae1 Positive_regulation of Gene_expression of Ccr2 1 0.04 4.98 0.42 5.00
101 INT237778 Il12b Positive_regulation of Gene_expression of Eae1 1 0.01 1.51 0.39 5.00
102 INT273045 Vip Regulation of Adcyap1 1 0.17 0.5 0.38 5.00
103 INT181438 Il4 Regulation of Gene_expression of Ccl2 1 0.38 0.74 0.35 5.00
104 INT181453 Gene_expression of Ccl2 Positive_regulation of Gene_expression of Il12rb1 1 0.06 1.87 0.34 5.00
105 INT181451 Lck Regulation of Mbp 1 0.08 1.43 0.34 5.00
106 INT350701 Mthfd1 Regulation of Gene_expression of Cd4 1 0.03 1.46 0.33 5.00
107 INT181435 Binding of Ccr2 and Hand2 1 0.17 1.81 0.32 5.00
108 INT181433 Hand2 Regulation of Gene_expression of Ccl2 1 0.12 0.68 0.32 5.00
109 INT313915 Binding of Il12a and Il23a 2 0.16 0.44 0.31 5.00
110 INT181432 Csf2 Positive_regulation of Ccl5 1 0.03 0.81 0.29 5.00
111 INT181442 Ccl2 Positive_regulation of Localization of Hand2 1 0.26 0.63 0.29 5.00
112 INT181446 Csf2 Positive_regulation of Ccl3 1 0.05 0.81 0.29 5.00
113 INT181454 Eae7 Regulation of Positive_regulation of Eae1 1 0.06 0.9 0.26 5.00
114 INT181449 Ccl7 Regulation of Ccl2 1 0.24 0.73 0.25 5.00
115 INT181445 Binding of Ccr5 and Hand1 1 0.12 1.01 0.22 5.00
116 INT260870 Binding of HLA-E and IL7R 1 0.19 0.5 0.22 5.00
117 INT181440 Binding of Ccr2 and Eae1 1 0.03 1.3 0.19 5.00
118 INT237777 Il23a Regulation of Localization of Il12a 1 0.19 0.93 0.19 5.00
119 INT350718 Mir106b Regulation of TGFB1 1 0.00 0.42 0.18 5.00
120 INT350603 MIR25 Regulation of TGFB1 1 0.01 0.42 0.18 5.00
121 INT350702 Rc3h1 Positive_regulation of Protein_catabolism of Icos 1 0.35 1.56 0.18 5.00
122 INT181457 Binding of CCL16 and Hand2 1 0.04 0.92 0.17 5.00
123 INT350717 MIR219-1 Negative_regulation of Zfp238 1 0.01 0.4 0.16 5.00
124 INT321957 Binding of Sar1a and Ceacam1 1 0.01 0.96 0.16 5.00
125 INT350719 MIR219-1 Negative_regulation of Foxj3 1 0.01 0.4 0.15 5.00
126 INT350713 MIR219-1 Negative_regulation of Pdgfra 1 0.00 0.4 0.15 5.00
127 INT350723 MIR219-1 Negative_regulation of Sox6 1 0.01 0.4 0.15 5.00
128 INT302676 Binding of OPA1 and MFN2 1 0.46 1.12 0.14 5.00
129 INT329118 Binding of KCNA1 and CNTN2 1 0.02 0 0.14 5.00
130 INT259023 CADPS Positive_regulation of Binding of SH2B2 1 0.06 2.05 0.14 5.00
131 INT350711 Ifnb1 Negative_regulation of Gene_expression of DICER1 1 0.03 0.15 0.14 5.00
132 INT237774 Il12b Positive_regulation of Eae1 1 0.01 0.58 0.13 5.00
133 INT284309 Tlr4 Positive_regulation of Mir155 3 0.18 0.51 0.11 5.00
134 INT327792 Binding of IGFALS and Alms1 1 0.00 1.15 0.11 5.00
135 INT350694 Uts2r Negative_regulation of Negative_regulation of Rc3h1 1 0.05 0.79 0.1 5.00
136 INT350695 Mir101a Positive_regulation of Protein_catabolism of Icos 1 0.05 0.8 0.1 5.00
137 INT237776 Ifna1 Positive_regulation of Eae1 1 0.07 0.66 0.09 5.00
138 INT350700 Binding of Bcl6 and thd 1 0.00 0.21 0.08 5.00
139 INT350721 Binding of Hand1 and TBX21 1 0.13 0.22 0.08 5.00
140 INT350692 Binding of Bcl6 and Hand1 1 0.02 0.16 0.08 5.00
141 INT350720 Binding of Bcl6 and TBX21 1 0.07 0.22 0.08 5.00
142 INT350708 Foxp3 Regulation of Socs1 1 0.08 0.21 0.07 5.00
143 INT329121 Binding of LGI1 and ADAM22 1 0.14 0.5 0.06 5.00
144 INT334683 Eae1 Regulation of Cnp 1 0.03 0.5 0.06 5.00
145 INT334687 Eae1 Regulation of Gene_expression of Cnp 1 0.06 0.5 0.06 5.00
146 INT334686 Olig1 Regulation of Plp1 1 0.17 0.55 0.06 5.00
147 INT334689 Olig1 Regulation of Gene_expression of Cnp 1 0.20 0.55 0.06 5.00
148 INT334684 Eae1 Regulation of Plp1 1 0.05 0.5 0.06 5.00
149 INT334682 Olig1 Regulation of Cnp 1 0.09 0.55 0.06 5.00
150 INT334685 Olig1 Regulation of Gene_expression of Plp1 1 0.17 0.55 0.06 5.00
151 INT334688 Eae1 Regulation of Gene_expression of Plp1 1 0.05 0.5 0.06 5.00
152 INT350704 Foxp3 Negative_regulation of Gene_expression of Mir142 1 0.02 0.13 0.04 5.00
153 INT350696 Mir31 Regulation of Gene_expression of Foxp3 1 0.04 0 0.03 5.00
154 INT247856 Narfl Negative_regulation of Gene_expression of Uchl1 1 0.03 1 0.03 5.00
155 INT321958 Binding of Vtn and Ceacam1 1 0.02 0.27 0 5.00
156 INT247847 Narfl Positive_regulation of Positive_regulation of Casp3 1 0.02 0.79 0 5.00
157 INT247853 Positive_regulation of Narfl Negative_regulation of Gene_expression of Uchl1 1 0.03 0.54 0 5.00
158 INT247846 Positive_regulation of Narfl Positive_regulation of Positive_regulation of Ube4a 1 0.00 0.82 0 5.00
159 INT350712 Binding of Gfi1 and MIR21 1 0.02 0.23 0 5.00
160 INT347723 Binding of Aqp4 and Tmed4 1 0.27 0 0 5.00
161 INT350710 Uts2r Negative_regulation of Gene_expression of MIR21 1 0.01 0 0 5.00
162 INT350706 Binding of Mef2c and Mir223 1 0.02 0.11 0 5.00
163 INT350715 Sfpi1 Positive_regulation of Transcription of MIR424 1 0.09 0.25 0 5.00
164 INT350707 Uts2r Negative_regulation of Gene_expression of Foxp3 1 0.03 0 0 5.00
165 INT247848 Narfl Negative_regulation of Uchl1 1 0.03 0.74 0 5.00
166 INT350714 Gtf3a Negative_regulation of Gene_expression of MIR17 1 0.00 0.22 0 5.00
167 INT302675 Binding of OPA1 and PLAA 1 0.15 0.73 0 5.00
168 INT247857 Narfl Positive_regulation of Gene_expression of Gfap 1 0.07 0.81 0 5.00
169 INT247888 Narfl Positive_regulation of CASP3 1 0.00 0.77 0 5.00
170 INT350722 Binding of Runx1 and Negative_regulation of Gene_expression of MIR17 1 0.01 0.22 0 5.00
171 INT247850 Positive_regulation of Narfl Regulation of Ube4a 1 0.00 1.86 0 5.00
172 INT247849 Edn1 Regulation of Gene_expression of Aqp4 1 0.12 1.05 0 5.00
173 INT247852 Narfl Positive_regulation of Localization of Aqp4 1 0.08 0.81 0 5.00
174 INT350705 Sfpi1 Positive_regulation of Mir223 1 0.04 0.13 0 5.00
175 INT247889 Positive_regulation of Narfl Positive_regulation of CASP3 1 0.00 0.84 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Neuromyelitis Optica. They are ordered first by their pain relevance and then by number of times they were reported in Neuromyelitis Optica. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT140413 Gene_expression of AQP4 113 0.78 139.25 25.53 100.00
2 INT140411 Gene_expression of Nqo1 45 0.60 62.35 8.7 100.00
3 INT157959 Binding of AQP4 32 0.48 43.44 7.44 100.00
4 INT140170 Binding of Nqo1 24 0.38 36.16 6.79 100.00
5 INT250282 Negative_regulation of AQP4 32 0.54 32.96 9.07 100.00
6 INT20205 Binding of IgG 108 0.46 66.68 8.57 100.00
7 INT143337 Binding of Aqp4 30 0.40 23.73 4.24 100.00
8 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 100.00
9 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 100.00
10 INT206760 Localization of Nqo1 8 0.09 15.76 2.4 100.00
11 INT169747 Localization of AQP4 17 0.75 16.64 2.79 100.00
12 INT84704 Positive_regulation of Nqo1 18 0.70 18.64 5.65 100.00
13 INT47714 Regulation of Nqo1 12 0.24 11.12 1.71 100.00
14 INT16449 Binding of IGHG3 67 0.48 39.55 10.59 100.00
15 INT72747 Localization of IgG 55 0.53 30.88 4.19 100.00
16 INT235953 Regulation of Binding of Aqp4 4 0.45 4.4 0.76 100.00
17 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93 100.00
18 INT235930 Regulation of Binding of 1 0.05 3.93 0.68 100.00
19 INT10870 Regulation of IgG 67 0.59 43.27 12.74 100.00
20 INT9220 Gene_expression of Ighg1 125 0.77 85.74 15.92 100.00
21 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78 100.00
22 INT23775 Regulation of S100B 24 0.62 16.75 2.57 100.00
23 INT84703 Negative_regulation of Nqo1 8 0.38 7.1 4.05 100.00
24 INT327776 Negative_regulation of Gene_expression of Nqo1 2 0.02 2.39 0.69 100.00
25 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 100.00
26 INT235936 Regulation of Regulation of NMO-IgG 1 0.05 1.97 0.34 100.00
27 INT77855 Gene_expression of Pain1 55 0.75 67.42 54.1 100.00
28 INT308715 Regulation of DDX41 1 0.08 2.12 0.12 100.00
29 INT52021 Regulation of IGHG3 34 0.39 22.43 3.3 100.00
30 INT179754 Regulation of Gene_expression of SLC1A2 3 0.34 0.93 1.32 100.00
31 INT46221 Positive_regulation of Gene_expression of IgG 46 0.53 33.66 7.7 100.00
32 INT165057 Binding of MID1 7 0.32 4.13 3.12 100.00
33 INT122410 Transcription of Nqo1 4 0.68 1.42 0.58 100.00
34 INT188884 Localization of DDX41 3 0.60 2.56 0.09 100.00
35 INT212916 Positive_regulation of Binding of 5 0.24 1.74 0.04 100.00
36 INT334150 Positive_regulation of Gene_expression of Nqo1 1 0.01 0.41 0.2 100.00
37 INT279975 Regulation of Gene_expression of Nqo1 1 0.02 0.1 0 100.00
38 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 99.98
39 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 99.98
40 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 99.98
41 INT188883 Binding of DDX41 9 0.39 11.55 1.29 99.98
42 INT14849 Binding of IgG-2a 12 0.39 5.96 6.06 99.98
43 INT98624 Regulation of Aqp4 27 0.62 30.76 3.77 99.96
44 INT140171 Binding of Aqp4 7 0.36 11.63 1.98 99.96
45 INT235950 Regulation of Regulation of Aqp4 1 0.37 1.96 0.34 99.96
46 INT179753 Gene_expression of SLC1A2 28 0.59 13.72 8.71 99.92
47 INT179749 Regulation of SLC1A2 3 0.34 2.28 1.99 99.92
48 INT78023 Gene_expression of DDX41 13 0.65 23.55 3.84 99.90
49 INT225965 Localization of Aqp4 26 0.81 18.85 3.75 99.90
50 INT250280 Positive_regulation of Negative_regulation of AQP4 1 0.37 0.58 0.17 99.90
51 INT225966 Regulation of Gene_expression of Aqp4 18 0.62 20.39 2.3 99.88
52 INT66191 Gene_expression of DBP 42 0.66 22.25 3.18 99.88
53 INT213244 Positive_regulation of Gene_expression of DBP 4 0.22 1.99 0.04 99.88
54 INT165821 Positive_regulation of Aqp4 27 0.70 24.37 3.22 99.84
55 INT84020 Positive_regulation of RNASE3 17 0.47 11.92 2.92 99.84
56 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 99.84
57 INT327780 Negative_regulation of Negative_regulation of AQP4 1 0.33 1.12 0.18 99.84
58 INT130837 Gene_expression of Aqp4 205 0.78 151.23 29.63 99.80
59 INT157960 Regulation of AQP4 11 0.48 21.36 3.06 99.80
60 INT116398 Gene_expression of Mog 25 0.77 23.11 6.33 99.80
61 INT160023 Regulation of Aqp4 9 0.45 8.41 4.19 99.80
62 INT141656 Regulation of Eae1 22 0.39 32.62 8.12 99.80
63 INT165460 Gene_expression of SLC1A3 15 0.75 7.19 5.43 99.76
64 INT250277 Regulation of Localization of SLC1A2 1 0.34 0.99 0.25 99.74
65 INT250274 Regulation of Localization of AQP5 1 0.16 0.77 0.04 99.74
66 INT250268 Regulation of Localization of SLC1A3 1 0.12 0.77 0.04 99.74
67 INT179756 Positive_regulation of Gene_expression of SLC1A2 8 0.38 2.95 3.06 99.72
68 INT250281 Positive_regulation of Positive_regulation of CD40LG 3 0.23 3.19 0.73 99.72
69 INT198870 Binding of Gpx3 5 0.01 2.47 0.81 99.70
70 INT131542 Negative_regulation of Gene_expression of APOE 6 0.40 3.92 0.33 99.68
71 INT5219 Negative_regulation of DBP 43 0.57 23.35 4.26 99.68
72 INT279981 Negative_regulation of Gene_expression of FGG 1 0.28 1.17 0 99.68
73 INT279979 Negative_regulation of Gene_expression of SERPINF1 1 0.26 1.16 0 99.68
74 INT56342 Gene_expression of TTR 34 0.78 16.5 2.05 99.68
75 INT213243 Negative_regulation of Gene_expression of DBP 7 0.42 2.68 0.2 99.68
76 INT272846 Negative_regulation of Gene_expression of A1BG 2 0.22 0.95 0.05 99.68
77 INT115701 Negative_regulation of Gene_expression of TTR 4 0.43 1.04 0.2 99.68
78 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 99.64
79 INT235935 Gene_expression of Cpsf3 1 0.04 1.5 0.14 99.64
80 INT235934 Gene_expression of Rnf141 1 0.07 1.49 0.14 99.64
81 INT155348 Positive_regulation of Aqp4 14 0.63 9.92 5.53 99.64
82 INT79476 Gene_expression of HLA-DMA 23 0.38 9.5 2.76 99.62
83 INT140414 Positive_regulation of AQP4 25 0.64 23.43 2.47 99.60
84 INT169748 Positive_regulation of Gene_expression of Aqp4 38 0.69 34.29 3.79 99.60
85 INT202935 Gene_expression of SERPINF1 12 0.50 7.53 1.54 99.60
86 INT179744 Negative_regulation of SLC1A2 16 0.45 12.32 6.14 99.58
87 INT10510 Negative_regulation of Igh-6 13 0.45 10.37 2.68 99.54
88 INT136304 Negative_regulation of Aqp4 54 0.59 48.42 7.4 99.52
89 INT250276 Localization of SLC1A2 1 0.61 2.4 0.44 99.52
90 INT250269 Localization of AQP5 1 0.26 0.77 0.04 99.52
91 INT250271 Localization of SLC1A3 1 0.20 0.77 0.04 99.52
92 INT58005 Gene_expression of M1 27 0.78 12.43 3.52 99.44
93 INT209108 Positive_regulation of Negative_regulation of GOPC 6 0.33 1.72 0.51 99.42
94 INT58563 Negative_regulation of S100B 13 0.51 11.75 1.77 99.40
95 INT109650 Gene_expression of Aqp4 87 0.78 51.52 20.72 99.32
96 INT36799 Negative_regulation of Ighm 21 0.41 17.47 3.65 99.32
97 INT725 Negative_regulation of IgG 62 0.41 37.21 8.16 99.32
98 INT206762 Gene_expression of LETM1 1 0.13 1.99 0.33 99.30
99 INT10855 Positive_regulation of Gene_expression of LAMC2 4 0.67 2.05 0.88 99.30
100 INT10847 Gene_expression of LAMC2 39 0.75 27 12.09 99.28
101 INT96814 Negative_regulation of APOE 13 0.59 10.64 1.61 99.28
102 INT104045 Regulation of Hand1 65 0.35 51.32 16.26 99.28
103 INT250272 Positive_regulation of Gene_expression of AQP4 11 0.54 9.79 1.85 99.24
104 INT70145 Gene_expression of Trav6-3 136 0.76 69.6 18.05 99.24
105 INT250279 Positive_regulation of Localization of AQP4 1 0.46 0.69 0.13 99.24
106 INT279982 Localization of APOA4 1 0.17 1.21 0.18 99.24
107 INT137453 Gene_expression of APOA4 2 0.17 1.21 0.26 99.24
108 INT235951 Positive_regulation of Positive_regulation of Aqp4 4 0.57 5.13 0.75 99.22
109 INT5842 Gene_expression of Gfap 372 0.78 153.71 127.71 99.18
110 INT5843 Positive_regulation of Gfap 184 0.70 108.2 70.21 99.16
111 INT250283 Positive_regulation of SLC1A2 5 0.53 3.22 2.29 99.14
112 INT9098 Positive_regulation of DBP 30 0.69 15.77 4.26 99.12
113 INT334680 Negative_regulation of Olig1 1 0.43 9.5 2.32 99.12
114 INT347721 Binding of Gt(pU21)40Imeg 1 0.01 0.23 0 99.12
115 INT79711 Binding of M1 11 0.27 3.77 0.58 99.08
116 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 99.04
117 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 99.04
118 INT327779 Regulation of Gene_expression of AQP4 5 0.48 4.5 0.6 99.04
119 INT250278 Binding of SLC1A2 1 0.28 1.52 0.24 98.98
120 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52 98.96
121 INT14887 Gene_expression of Mbp 55 0.75 36.13 16.11 98.96
122 INT78941 Positive_regulation of DDX41 4 0.45 2.46 0.23 98.92
123 INT250273 Localization of EEA1 1 0.26 0.75 0.1 98.84
124 INT87361 Negative_regulation of TTR 25 0.57 5.74 1.51 98.84
125 INT235954 Gene_expression of Bcr 1 0.13 6.77 1.47 98.80
126 INT1127 Negative_regulation of IGHG3 32 0.28 21.1 7.37 98.80
127 INT1124 Negative_regulation of CD40LG 53 0.57 36.26 7 98.80
128 INT125237 Negative_regulation of Gene_expression of CD40LG 16 0.54 9.9 3.27 98.80
129 INT250284 Gene_expression of AQP5 4 0.61 5.68 0.29 98.74
130 INT164480 Negative_regulation of Gene_expression of Aqp4 14 0.58 10.84 1.52 98.72
131 INT124250 Binding of APOA4 3 0.18 4.83 0.53 98.64
132 INT235946 Positive_regulation of Localization of Aqp4 1 0.41 1.32 0.25 98.62
133 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 98.56
134 INT6861 Negative_regulation of Gfap 32 0.58 13.71 7.22 98.52
135 INT51064 Regulation of Gene_expression of S100B 13 0.60 5.02 1.34 98.52
136 INT251679 Negative_regulation of Gene_expression of AQP4 2 0.38 10.37 0.77 98.52
137 INT230495 Regulation of Gene_expression of Alms1 4 0.04 4.53 0.53 98.50
138 INT104563 Localization of Aqp4 10 0.73 7.82 2.54 98.48
139 INT1536 Negative_regulation of NA 244 0.55 52.67 59.79 98.48
140 INT215923 Positive_regulation of Mog 8 0.19 9.86 3.17 98.48
141 INT308714 Regulation of Gene_expression of DDX41 1 0.08 1.9 0.19 98.44
142 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 98.40
143 INT3795 Positive_regulation of Ighm 46 0.68 22.43 6.47 98.40
144 INT135407 Negative_regulation of Ccl2 33 0.57 32.74 9.45 98.40
145 INT279986 Protein_catabolism of HP 1 0.18 0.23 0 98.32
146 INT79709 Regulation of M1 13 0.24 4.8 4.9 98.24
147 INT173512 Positive_regulation of Gene_expression of Alms1 12 0.44 8.66 1.95 98.18
148 INT327785 Transcription of AQP4 3 0.56 2.19 0.23 98.08
149 INT179750 Negative_regulation of Gene_expression of SLC1A2 3 0.45 3.05 2.15 97.96
150 INT6623 Gene_expression of NA 231 0.78 45.78 59.36 97.96
151 INT49930 Binding of Ighg1 21 0.37 13.27 2.43 97.92
152 INT9695 Negative_regulation of Csf2 41 0.57 31.65 6.28 97.92
153 INT64982 Positive_regulation of Ifnb1 10 0.48 6.16 2.35 97.84
154 INT96588 Gene_expression of MOG 18 0.75 11.41 1.89 97.56
155 INT11303 Gene_expression of Avp 116 0.78 39.23 23.88 97.50
156 INT39374 Gene_expression of Sct 5 0.68 1.42 3.89 97.50
157 INT12922 Gene_expression of Atp9a 115 0.75 50.95 17.01 97.44
158 INT155667 Negative_regulation of Gene_expression of Gja1 3 0.42 1.16 0.1 97.36
159 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 96.98
160 INT37758 Gene_expression of GC 10 0.75 7.09 1.75 96.96
161 INT234116 Positive_regulation of MID1 9 0.03 3.78 1.61 96.94
162 INT235938 Binding of Mog 3 0.34 9.61 3.09 96.88
163 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 96.80
164 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 96.80
165 INT69156 Localization of IL5 21 0.68 14.95 5.37 96.70
166 INT101243 Regulation of STAT3 12 0.62 9.98 1.92 96.64
167 INT235931 Regulation of Gene_expression of Mog 1 0.15 1.58 0.36 96.64
168 INT261215 Localization of Sct 2 0.44 1.01 0.17 96.52
169 INT235948 Regulation of Gene_expression of Bcr 1 0.08 1.58 0.36 96.48
170 INT87780 Gene_expression of Gja1 22 0.77 5.84 4.24 96.44
171 INT15610 Localization of GOPC 223 0.65 68.26 28.7 96.20
172 INT318025 Gene_expression of Gjb6 1 0.13 0.33 0.07 96.08
173 INT152961 Negative_regulation of Gene_expression of Aqp4 13 0.59 10.01 2.92 96.04
174 INT244768 Gene_expression of Olig1 2 0.77 3.56 1.19 96.04
175 INT111047 Negative_regulation of Gene_expression of Aqp2 3 0.34 3.56 0.09 96.04
176 INT19330 Binding of HLA-A 99 0.48 76.26 22.85 95.76
177 INT104569 Gene_expression of Aqp2 23 0.60 16.56 12.23 95.76
178 INT236159 Gene_expression of Mir326 2 0.11 4.93 1.65 95.68
179 INT193064 Regulation of Gene_expression of M1 2 0.04 1.34 0.36 95.60
180 INT57638 Positive_regulation of M1 7 0.40 6.08 5.03 95.44
181 INT279976 Regulation of APOA4 1 0.12 1.23 0.18 95.28
182 INT104567 Gene_expression of Aqp1 47 0.78 44.84 28.68 95.24
183 INT77670 Positive_regulation of ACLY 24 0.49 21.68 3.12 95.08
184 INT143551 Binding of KCNA1 13 0.46 8.81 2.81 94.96
185 INT137767 Gene_expression of Eae1 74 0.34 89.32 20.48 94.84
186 INT14778 Gene_expression of FCGR3A 25 0.75 16.25 3.86 94.76
187 INT279977 Transcription of FGG 1 0.47 1.3 0.2 94.28
188 INT106709 Binding of LAMB2 13 0.06 4.89 1.26 94.20
189 INT247868 Positive_regulation of Narfl 1 0.11 37.11 0.68 94.16
190 INT15367 Gene_expression of OPA1 35 0.67 24.9 5.45 94.08
191 INT209406 Gene_expression of FGG 2 0.45 2.93 0 93.96
192 INT7206 Binding of HBG1 14 0.47 3.44 2.14 93.92
193 INT159640 Negative_regulation of Regulation of Aqp4 1 0.42 0.78 0.18 93.84
194 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 93.84
195 INT143006 Gene_expression of A1BG 23 0.73 22.92 0.88 93.76
196 INT109558 Binding of Eae1 9 0.25 10.36 3.16 93.76
197 INT147063 Negative_regulation of Atp11c 3 0.06 2.28 0.61 93.32
198 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68 91.96
199 INT163592 Localization of CISH 5 0.54 5.9 1.26 91.76
200 INT28204 Positive_regulation of Localization of F13A1 5 0.45 3.12 0.57 91.44
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