D:Neuropathic Pain

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pChart

Disease Term
Synonyms Allodynia, Chronic Pain Neuropathic Pain, Neuropathic, Neuropathic Neuralgia, Neuropathy, Painful Diabetic Neuropathy Neuropathic Pain, Peripheral Neuropathic Pain, TACTILE ALLODYNIA
Documents 13295
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Neuropathic Pain. They are ordered first by their relevance to Neuropathic Pain and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT283543 Binding of GARS and Setx 1 0.01 3.71 0 100.00
2 INT283542 Binding of SPG19 and Setx 1 0.06 3.69 0 100.00
3 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95 100.00
4 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93 100.00
5 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93 100.00
6 INT281373 Tcf21 Regulation of Fig4 1 0.03 0.67 1.2 100.00
7 INT149743 Ean5 Positive_regulation of Gene_expression of P2rx2 1 0.10 1.54 1.5 100.00
8 INT329409 Binding of SPTLC1 and Dstn 1 0.05 1.3 0.23 100.00
9 INT281381 FSCN1 Positive_regulation of Gene_expression of Gfap 1 0.06 1.13 1.98 100.00
10 INT249483 Binding of Ephb1 and Efnb2 1 0.02 2.35 1.66 100.00
11 INT329410 Binding of SPTLC1 and Spt 1 0.04 1 0.35 100.00
12 INT161670 H2-M3 Positive_regulation of Positive_regulation of Mapk1 1 0.14 0.73 1.41 100.00
13 INT86997 Binding of HIVEP1 and NGF 2 0.03 1.75 1.73 100.00
14 INT281382 FSCN1 Positive_regulation of Sds 1 0.02 0.84 1.33 100.00
15 INT249481 Positive_regulation of Binding of Ephb1 and Efnb2 1 0.03 1.36 1.12 100.00
16 INT155460 Tnfrsf1a Positive_regulation of Positive_regulation of Nfkb1 1 0.42 2.39 1.82 100.00
17 INT140892 Penk Negative_regulation of Mnp 1 0.13 0.55 1.75 100.00
18 INT76396 Il10 Negative_regulation of Il1b 2 0.65 1.89 1.08 100.00
19 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47 100.00
20 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47 100.00
21 INT190775 Gene_expression of Il4 Negative_regulation of Positive_regulation of FOSL1 1 0.39 2.42 1.4 100.00
22 INT160119 EPO Regulation of Gene_expression of NFKB1 1 0.02 0.2 0.64 100.00
23 INT114844 Lgals1 Positive_regulation of TACR1 1 0.16 0.95 0.82 100.00
24 INT146780 Positive_regulation of Fgfr1 Positive_regulation of Mapk14 1 0.34 0.95 0.77 100.00
25 INT113338 Binding of EPO and KNCN 1 0.02 1.39 0.62 100.00
26 INT283533 Binding of GARS and SPG19 1 0.00 1.72 0 99.96
27 INT161048 Nrm Positive_regulation of Prdm4 1 0.56 1.47 0.86 99.96
28 INT219279 Ctss Positive_regulation of Gene_expression of Fam64a 1 0.06 1.39 0.96 99.96
29 INT219273 Fam64a Positive_regulation of Gene_expression of Ctss 1 0.06 1.39 0.96 99.96
30 INT281380 Fos Negative_regulation of Gene_expression of FSCN1 1 0.07 0.4 0.96 99.96
31 INT4975 Binding of ITIH4 and MAG 1 0.44 2.24 0.39 99.92
32 INT125699 CR1 Negative_regulation of Positive_regulation of ABCA1 1 0.03 0.64 0.53 99.92
33 INT300864 Ngf Positive_regulation of Mapk14 2 0.60 1.38 1.32 99.92
34 INT153815 LPA Positive_regulation of Gene_expression of Gtf3a 1 0.00 0.16 0.1 99.92
35 INT85783 PRKG1 Regulation of Prkcg 1 0.09 0.38 0.9 99.84
36 INT85782 Rb1 Regulation of PRKG1 1 0.00 0.38 0.37 99.84
37 INT79759 Ngf Regulation of Il6 1 0.60 4.62 5.62 99.80
38 INT155663 Positive_regulation of P2rx4 Positive_regulation of Localization of Bdnf 1 0.42 0.84 1.25 99.80
39 INT281375 Il1r1 Negative_regulation of Gene_expression of Fos 1 0.47 0.61 0.97 99.80
40 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98 99.78
41 INT265015 Pgr Positive_regulation of Sds 1 0.04 0.49 0.37 99.72
42 INT113743 Mc3r Regulation of Gene_expression of Agrp 1 0.05 0.9 0.98 99.70
43 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88 99.68
44 INT161225 Ccl2 Positive_regulation of Ccl2 Positive_regulation of Ccr2 1 0.57 2.09 1.88 99.68
45 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73 99.64
46 INT155459 Tnfrsf1a Positive_regulation of Nfkb1 1 0.42 2.45 1.63 99.60
47 INT165183 Ifnb1 Positive_regulation of P2rx4 1 0.04 1.73 1.73 99.56
48 INT85780 Prkaca Regulation of Prkcg 1 0.29 0.47 1.17 99.52
49 INT85778 Rb1 Regulation of Prkaca 1 0.00 0.38 0.36 99.52
50 INT210696 Trpv1 Regulation of Slc12a2 1 0.25 1.97 2.58 99.50
51 INT281379 Tcf21 Regulation of FSCN1 1 0.01 0.66 1.19 99.48
52 INT116102 Cck Positive_regulation of Negative_regulation of Pnoc 1 0.51 0.41 1.33 99.48
53 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63 99.44
54 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75 99.36
55 INT161769 Cck Regulation of Cckar 1 0.27 0.53 0.92 99.36
56 INT85779 Rb1 Regulation of Prkcg 1 0.01 0.38 0.36 99.32
57 INT351366 LPA Positive_regulation of Rab38 1 0.00 0.95 1.53 99.32
58 INT159837 Trim2 Negative_regulation of Transcription of Fos 1 0.10 1.92 1.22 99.28
59 INT158282 Binding of Penk and Csf2 1 0.33 0.87 1.44 99.24
60 INT275390 Binding of Ccr5 and Htatsf1 1 0.01 3.26 0.97 99.24
61 INT275386 Binding of Cxcr4 and Htatsf1 1 0.01 3.25 0.97 99.24
62 INT139642 Positive_regulation of Jun Regulation of Gene_expression of Npy 1 0.21 1.07 0.97 99.22
63 INT65724 Binding of Pnoc and Oprl1 8 0.33 2.94 8.82 99.20
64 INT310066 Negative_regulation of Pain1 Positive_regulation of Faah 1 0.03 1.32 1.23 99.16
65 INT310069 Negative_regulation of Pain1 Positive_regulation of Mgll 1 0.02 1.32 1.23 99.16
66 INT310068 Pain1 Positive_regulation of Faah 1 0.03 1.3 1.22 99.16
67 INT310067 Pain1 Positive_regulation of Mgll 1 0.02 1.29 1.21 99.16
68 INT158283 Binding of Penk and Accn4 1 0.07 0.87 1.43 99.04
69 INT296950 Tacr1 Negative_regulation of Gene_expression of Cck 1 0.30 0.94 1.11 99.04
70 INT81520 Binding of PNOC and Oprl1 1 0.24 0.1 0.75 99.04
71 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75 99.02
72 INT275406 Binding of ITIH4 and Ccr5 1 0.09 2.88 0.97 99.00
73 INT275409 Binding of ITIH4 and Cxcr4 1 0.09 2.87 0.97 99.00
74 INT102201 Tnf Regulation of Il1b 3 0.39 2.57 0.82 99.00
75 INT110994 Tnf Regulation of Il6 1 0.17 0.67 0.36 99.00
76 INT130839 Gfap Positive_regulation of S100B 1 0.51 1.9 1.56 98.96
77 INT130838 Gfap Positive_regulation of Aqp4 1 0.51 1.9 1.56 98.96
78 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58 98.96
79 INT283539 Binding of Litaf and Mad2l1bp 1 0.00 0.67 0.11 98.92
80 INT146495 Snta1 Positive_regulation of Adrbk1 1 0.14 0.68 0.85 98.76
81 INT286798 Binding of Il6st and Cntf 1 0.10 1.34 0.97 98.76
82 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25 98.72
83 INT152857 PRS Regulation of Nefl 1 0.00 0.19 0.77 98.72
84 INT152833 Nefl Regulation of Prkcg 1 0.12 0.19 0.77 98.72
85 INT152831 Nefh Regulation of Prkcg 1 0.05 0.19 0.77 98.72
86 INT152832 Nefm Regulation of Nefh 1 0.12 0.19 0.77 98.72
87 INT152836 Nefm Regulation of Prkcg 1 0.15 0.19 0.77 98.72
88 INT152855 PRS Regulation of Nefh 1 0.00 0.19 0.77 98.72
89 INT152856 PRS Regulation of Nefm 1 0.00 0.19 0.77 98.72
90 INT152834 Nefl Regulation of Nefh 1 0.10 0.19 0.77 98.72
91 INT152854 PRS Regulation of Prkcg 1 0.01 0.19 0.76 98.72
92 INT127585 Binding of CNR2 and Ctbp1 1 0.00 0.6 0.76 98.64
93 INT127584 Binding of CNR1 and Ctbp1 1 0.00 0.6 0.75 98.64
94 INT124435 Gene_expression of Chrna9 Positive_regulation of Phosphorylation of Creb1 1 0.11 0.6 1.17 98.60
95 INT169346 Nxn Negative_regulation of Dynll1 1 0.06 1.22 1.87 98.60
96 INT281155 Binding of ITIH4 and Ddc 1 0.09 1.27 0.37 98.56
97 INT128978 Cnr1 Positive_regulation of Cnr2 1 0.56 0.96 0.65 98.48
98 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31 98.48
99 INT283934 Phax Negative_regulation of Positive_regulation of Mapk14 1 0.03 2.06 1.09 98.48
100 INT139638 Positive_regulation of Jun Positive_regulation of Positive_regulation of Npy 1 0.36 1.18 0.96 98.40
101 INT139641 Positive_regulation of Jun Positive_regulation of Positive_regulation of Vip 1 0.37 0.95 0.99 98.40
102 INT73016 PDYN Regulation of TAC1 1 0.29 0.34 1.54 98.40
103 INT291578 Negative_regulation of Pde12 Positive_regulation of Pde5a 1 0.03 1.11 1.67 98.32
104 INT160653 Binding of P2rx1 and Ptgfr 1 0.28 0.66 1.14 98.24
105 INT209087 Crh Positive_regulation of Ceacam3 1 0.24 1.45 1.54 98.24
106 INT137092 Ntf3 Negative_regulation of Gene_expression of Gal 1 0.47 1.01 0.9 98.20
107 INT146496 Snta1 Positive_regulation of Gene_expression of Adrbk1 1 0.13 0.73 1.05 98.16
108 INT125284 FSCN1 Positive_regulation of Positive_regulation of EPHB2 1 0.04 0.4 1.14 98.16
109 INT140532 Gtf3a Positive_regulation of DYT10 1 0.12 1.83 1.34 98.16
110 INT140531 Ngf Positive_regulation of DYT10 1 0.72 1.83 1.34 98.16
111 INT89514 Pnoc Regulation of Gene_expression of Fos 1 0.47 0.98 0.93 98.16
112 INT134681 FSCN1 Positive_regulation of FSCN1 Positive_regulation of MAPK8 1 0.00 0.56 1.39 98.12
113 INT134679 FSCN1 Positive_regulation of MAPK8 1 0.01 0.56 1.39 98.12
114 INT107104 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.42 1.86 1.34 98.08
115 INT349658 Nos2 Regulation of Gene_expression of Nos1 1 0.63 2.86 1.84 98.04
116 INT146306 Binding of Chrna9 and Myo5c 1 0.01 0.27 0.48 98.04
117 INT155259 RUNX1 Negative_regulation of Tnf 1 0.00 1.48 0.93 97.98
118 INT89515 Pnoc Regulation of Gene_expression of Fosl1 1 0.09 0.98 0.93 97.96
119 INT72754 Adamts7 Negative_regulation of TNF 1 0.28 1.64 1.13 97.92
120 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82 97.84
121 INT91267 Gdnf Negative_regulation of Gdnf 1 0.05 0.81 0.58 97.84
122 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56 97.84
123 INT164150 Binding of S100a8 and Trpv1 1 0.04 0.6 0.62 97.84
124 INT314210 Ngf Regulation of Phosphorylation of Mapk14 1 0.34 0.85 1.84 97.76
125 INT127876 ACE Positive_regulation of Protein_catabolism of CALCA 1 0.28 0.63 0.75 97.68
126 INT126384 Binding of Bdnf and Ntrk2 Positive_regulation of Prkca 1 0.49 0.63 0.85 97.64
127 INT139636 Jun Negative_regulation of Phosphorylation of Npy 1 0.33 1.07 1.01 97.64
128 INT139639 Jun Negative_regulation of Positive_regulation of Vip 1 0.53 1.07 1 97.64
129 INT139643 Jun Negative_regulation of Positive_regulation of Npy 1 0.33 1.07 1 97.64
130 INT68514 Pnoc Positive_regulation of Oprl1 10 0.59 3.56 9.57 97.60
131 INT165724 Bdkrb1 Positive_regulation of Adora1 1 0.24 1.65 0.43 97.60
132 INT270218 P2rx3 Positive_regulation of Pla2g4a 1 0.34 0.63 0.85 97.48
133 INT262577 Localization of Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.05 0.92 0.75 97.48
134 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46 97.44
135 INT263072 Kncn Regulation of Transcription of Trpm8 1 0.08 0.99 0.36 97.36
136 INT105668 Binding of AAVS1 and BDNF 1 0.08 0.94 0.95 97.28
137 INT349657 Nos2 Regulation of Regulation of Nos1 1 0.24 0.9 0.8 97.26
138 INT308174 Binding of TNF and P2rx7 1 0.02 0.84 0.56 97.24
139 INT281241 Positive_regulation of P2RX7 Negative_regulation of Gene_expression of P2rx3 1 0.03 0.79 0.71 97.16
140 INT244421 Binding of DST and Ctss 1 0.02 0.42 0.41 97.08
141 INT275398 Binding of ITIH4 and Htatsf1 1 0.02 5.05 2.24 97.04
142 INT128044 Bdnf Positive_regulation of Ephb1 2 0.31 1.89 2.57 97.04
143 INT96811 Nfkb1 Regulation of Gene_expression of IK 1 0.00 1.06 0.87 97.00
144 INT274948 Binding of Dh and Ltp 1 0.11 0.55 1.23 97.00
145 INT281085 Binding of Gria2 and Nsf 2 0.26 0.4 0.94 97.00
146 INT275387 Binding of Lamp1 and Ccr5 1 0.01 1.45 0.52 96.96
147 INT275405 Binding of GOLPH3 and Ccr5 1 0.00 1.46 0.52 96.96
148 INT116227 Pnoc Negative_regulation of NAV1 1 0.02 0.1 0.48 96.92
149 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 96.88
150 INT314211 Ngf Positive_regulation of Gene_expression of Agtrap 1 0.04 1.15 1.3 96.88
151 INT165324 Binding of TRPV4 and Trpv4 1 0.11 0.66 0.1 96.68
152 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17 96.64
153 INT166135 Regulation of Binding of Cxcl12 and Cxcr4 1 0.30 0.9 0.91 96.64
154 INT82267 Lif Regulation of Gene_expression of Gal 1 0.40 2.76 0.62 96.64
155 INT156608 Trpv1 Regulation of Nav1 1 0.51 0.52 0.95 96.60
156 INT296484 Binding of Gria2 and GRIP1 1 0.04 4.52 4.59 96.52
157 INT275388 Binding of Lamp1 and Cxcr4 1 0.01 1.45 0.52 96.48
158 INT275403 Binding of Cxcr4 and GOLPH3 1 0.00 1.45 0.52 96.48
159 INT256298 Binding of Creb1 and Ephb1 1 0.16 1.27 1.22 96.44
160 INT256294 Binding of Grin2b and Ephb1 1 0.28 1.11 1.08 96.44
161 INT131574 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Creb1 1 0.41 0.33 1.58 96.44
162 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36 96.36
163 INT314213 Mapk14 Positive_regulation of Agtrap 1 0.04 1.15 1.34 96.32
164 INT314212 Mapk14 Positive_regulation of Gene_expression of Agtrap 1 0.06 1.09 1.24 96.32
165 INT314198 Mapk14 Positive_regulation of Gene_expression of Trpv1 1 0.48 1.09 1.24 96.32
166 INT139230 Icam1 Negative_regulation of Cmklr1 1 0.19 1.13 1.07 96.24
167 INT139229 Calca Negative_regulation of Cmklr1 1 0.19 1.12 1.06 96.24
168 INT308173 Binding of DRG1 and Tnfrsf1b 1 0.01 1.64 1.1 96.20
169 INT308167 Binding of Eln and Tnfrsf1b 1 0.01 0.94 0.71 96.20
170 INT256297 Binding of Creb1 and Insrr 1 0.00 1.22 1.19 96.20
171 INT256293 Binding of Grin2b and Insrr 1 0.01 1.06 1.05 96.20
172 INT287754 Lpar2 Positive_regulation of Gene_expression of Lpar1 1 0.44 0.48 0.39 96.20
173 INT287743 Lpar2 Positive_regulation of Positive_regulation of Lpar1 1 0.44 0.48 0.39 96.20
174 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54 95.92
175 INT199493 Ngf Regulation of Oprd1 1 0.05 1.05 1.15 95.88
176 INT69340 Binding of Igh-6 and Ngf 2 0.06 1.04 1.06 95.80
177 INT72213 Positive_regulation of PRKCA Regulation of Gene_expression of METTL3 1 0.05 0.17 0.93 95.76
178 INT153963 Gatsl2 Regulation of Abat 1 0.02 0.97 1.03 95.72
179 INT287751 Rbm39 Positive_regulation of Positive_regulation of Lpar1 1 0.01 0.48 0.39 95.64
180 INT287745 Rbm39 Positive_regulation of Gene_expression of Lpar1 1 0.01 0.48 0.39 95.64
181 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85 95.56
182 INT292988 Negative_regulation of SGCG Positive_regulation of GABRB3 1 0.01 0.3 0.89 95.56
183 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22 95.48
184 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19 95.40
185 INT287744 Lpar3 Positive_regulation of Positive_regulation of Lpar1 1 0.46 0.39 0.58 95.36
186 INT287753 Lpar3 Positive_regulation of Gene_expression of Lpar1 1 0.46 0.39 0.58 95.36
187 INT144450 Regulation of Nqo1 Regulation of Nos1 1 0.11 0.1 0.34 95.36
188 INT139227 Icam1 Negative_regulation of Timp1 1 0.37 1.13 1.06 95.12
189 INT139231 Calca Negative_regulation of Timp1 1 0.36 1.11 1.05 95.12
190 INT344973 Negative_regulation of Mmp23 Regulation of Negative_regulation of Mag 1 0.01 1.14 0.99 95.12
191 INT182704 Binding of NPFF and TP53INP2 1 0.01 0.73 3.28 95.08
192 INT283050 Binding of Gad2 and Trpm8 1 0.23 2.02 1.93 95.04
193 INT345180 Binding of Lpar4 and Gpr87 1 0.06 0.69 0.59 95.04
194 INT345192 Binding of Gpr87 and Lpar5 1 0.07 0.69 0.59 95.04
195 INT134686 FSCN1 Positive_regulation of Gfap 1 0.00 0.71 1.89 94.92
196 INT305335 Olfr927-ps1 Negative_regulation of Akr1b3 1 0.02 1.6 0.17 94.64
197 INT284785 Gch1 Regulation of Bh4p 1 0.00 1.48 1.54 94.64
198 INT334351 Bdnf Regulation of Positive_regulation of Ephb1 1 0.18 1.27 1.2 94.48
199 INT132689 Tnf Regulation of Dnajc13 1 0.01 1.27 0.65 94.36
200 INT274865 Positive_regulation of Mapk1 Negative_regulation of Gene_expression of TNF 1 0.04 1.08 0.35 94.28

Single Events

The table below shows the top 200 pain related interactions that have been reported for Neuropathic Pain. They are ordered first by their pain relevance and then by number of times they were reported in Neuropathic Pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT86521 Gene_expression of Lpar1 167 0.78 154.61 80.35 100.00
2 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 100.00
3 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1 100.00
4 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 100.00
5 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 100.00
6 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73 100.00
7 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 100.00
8 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41 100.00
9 INT104523 Positive_regulation of FSCN1 14 0.12 10.09 20.08 100.00
10 INT6864 Positive_regulation of Gene_expression of Gfap 110 0.70 59.01 47.07 100.00
11 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48 100.00
12 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03 100.00
13 INT77855 Gene_expression of Pain1 55 0.75 67.42 54.1 100.00
14 INT84495 Positive_regulation of Positive_regulation of Ephb1 85 0.70 46.12 54.11 100.00
15 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
16 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 100.00
17 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75 100.00
18 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92 100.00
19 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43 100.00
20 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132 100.00
21 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 100.00
22 INT97368 Negative_regulation of Nav1 62 0.59 41.56 60.27 100.00
23 INT24569 Negative_regulation of Pain1 26 0.41 21.82 21.08 100.00
24 INT166119 Negative_regulation of Gene_expression of Lpar1 17 0.51 13.86 8.7 100.00
25 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25 100.00
26 INT5307 Regulation of Tnf 87 0.62 78.71 43.4 100.00
27 INT5380 Positive_regulation of Gene_expression of Fos 243 0.70 105.65 131.05 100.00
28 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78 100.00
29 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 100.00
30 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 100.00
31 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 100.00
32 INT47680 Regulation of Gene_expression of Bdnf 92 0.62 41.61 53.24 100.00
33 INT10706 Regulation of Il6 150 0.62 93.23 62.34 100.00
34 INT215353 Gene_expression of Tcf21 16 0.59 9.71 9.49 100.00
35 INT195203 Binding of Tenc1 14 0.32 13.97 8.28 100.00
36 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 100.00
37 INT49553 Regulation of Gene_expression of Gfap 42 0.62 17.04 23.65 100.00
38 INT237653 Gene_expression of Sfn 6 0.59 5.54 2.26 100.00
39 INT82882 Localization of Ccl2 61 0.80 41.96 28 100.00
40 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47 100.00
41 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33 100.00
42 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 100.00
43 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74 100.00
44 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59 100.00
45 INT78234 Positive_regulation of Gene_expression of P2rx2 18 0.69 12.86 12.75 100.00
46 INT5590 Negative_regulation of Fos 144 0.59 40.94 81.98 100.00
47 INT109724 Phosphorylation of FSCN1 5 0.07 3.15 8.82 100.00
48 INT84171 Negative_regulation of Gene_expression of Ccl2 30 0.58 26.37 18.28 100.00
49 INT26973 Gene_expression of Tenc1 59 0.66 27.19 12 100.00
50 INT237655 Binding of Sfn 1 0.42 3.62 2.55 100.00
51 INT129685 Negative_regulation of FSCN1 7 0.05 3.44 5.69 100.00
52 INT101474 Positive_regulation of Gene_expression of Gfap 61 0.70 38.3 10.35 100.00
53 INT90943 Negative_regulation of P2rx1 13 0.42 8.21 7.22 100.00
54 INT51602 Gene_expression of Grm5 59 0.75 17.29 26.99 100.00
55 INT76621 Positive_regulation of Cnr2 32 0.69 17.77 26.57 100.00
56 INT65057 Regulation of Nfkb1 28 0.47 16.48 11.62 100.00
57 INT81537 Regulation of Gene_expression of Nfkb1 10 0.57 7.09 7.48 100.00
58 INT62426 Gene_expression of Mc1r 127 0.78 42.99 48.01 100.00
59 INT178828 Regulation of Pain1 12 0.14 16.1 15.64 100.00
60 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57 100.00
61 INT65537 Positive_regulation of Positive_regulation of Nfkb1 52 0.67 30.6 26.35 100.00
62 INT6110 Negative_regulation of Gene_expression of Ins1 83 0.56 60.59 16.07 100.00
63 INT72884 Positive_regulation of Tenc1 13 0.42 14.01 7.67 100.00
64 INT125384 Positive_regulation of Pain1 23 0.49 17.1 14.83 100.00
65 INT8732 Positive_regulation of Gene_expression of Oprm1 76 0.70 22.59 58.83 100.00
66 INT26972 Negative_regulation of Tenc1 57 0.57 56.71 16.87 100.00
67 INT91100 Binding of SPTLC1 10 0.47 12.85 5.71 100.00
68 INT161221 Positive_regulation of Positive_regulation of Ccr2 3 0.50 4.55 3.98 100.00
69 INT81955 Positive_regulation of SPTLC1 12 0.70 10.25 3.12 100.00
70 INT126047 Regulation of Phosphorylation of Mapk14 7 0.60 5.05 5.03 100.00
71 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71 100.00
72 INT281367 Regulation of Gene_expression of Tcf21 1 0.09 1.39 2.89 100.00
73 INT92517 Gene_expression of Grin1 105 0.78 29.53 39.43 100.00
74 INT9299 Positive_regulation of Positive_regulation of Npr1 32 0.53 6.65 16.72 100.00
75 INT5948 Regulation of Il1b 44 0.60 22.8 25.4 100.00
76 INT281369 Negative_regulation of Gene_expression of Tcf21 1 0.08 1.4 2.44 100.00
77 INT63536 Gene_expression of Syncrip 7 0.67 7.23 5.44 100.00
78 INT9660 Regulation of TNF 363 0.62 312.94 139.99 100.00
79 INT85964 Gene_expression of Pecam1 109 0.78 69.73 15.21 100.00
80 INT237651 Negative_regulation of Sfn 3 0.51 1.7 0.49 100.00
81 INT29170 Negative_regulation of Gene_expression of Il1b 25 0.59 16.36 13.68 100.00
82 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36 100.00
83 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55 100.00
84 INT215593 Binding of P2ry6 1 0.31 2.53 2.09 100.00
85 INT183249 Binding of P2ry12 12 0.47 7.4 3.3 100.00
86 INT3550 Negative_regulation of GLA 52 0.59 33.93 5.26 100.00
87 INT55578 Regulation of Gene_expression of Il1b 7 0.62 4.74 5.55 100.00
88 INT12424 Binding of Npy 48 0.48 8.23 24.26 100.00
89 INT145097 Negative_regulation of Pain1 16 0.22 19.11 16.82 100.00
90 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99 100.00
91 INT44979 Positive_regulation of Pnp 11 0.59 5.61 2.41 100.00
92 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 100.00
93 INT98260 Negative_regulation of Gene_expression of Bdkrb1 4 0.57 5.98 6.7 100.00
94 INT6867 Positive_regulation of Gene_expression of GFAP 22 0.67 13.46 9.75 100.00
95 INT283536 Binding of Setx 1 0.36 3.69 0 100.00
96 INT58079 Localization of Tenc1 13 0.68 5.9 4.75 100.00
97 INT46605 Positive_regulation of NAA50 17 0.49 6.33 1.76 100.00
98 INT211853 Phosphorylation of Tenc1 2 0.61 2.53 1.59 100.00
99 INT14264 Binding of Gal 39 0.47 5.7 14.48 100.00
100 INT110318 Gene_expression of CAPN1 1 0.04 1.97 0.82 100.00
101 INT4877 Gene_expression of MME 184 0.78 122.82 24.78 100.00
102 INT905 Regulation of Ptgfr 8 0.35 2.87 2.28 100.00
103 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66 100.00
104 INT5986 Negative_regulation of Plec 1 0.18 1.56 1.08 100.00
105 INT164248 Positive_regulation of MPZ 18 0.67 24.54 2.16 100.00
106 INT24527 Negative_regulation of Gal 12 0.59 7.16 6.29 100.00
107 INT122300 Negative_regulation of Positive_regulation of Nqo1 2 0.59 1.07 1.84 100.00
108 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64 100.00
109 INT87139 Negative_regulation of Positive_regulation of Il6 18 0.59 10.65 7.76 100.00
110 INT79758 Regulation of Gene_expression of Gal 6 0.54 5.45 3.22 100.00
111 INT99587 Positive_regulation of Gene_expression of Oprk1 15 0.57 5.26 12.39 100.00
112 INT15462 Negative_regulation of Il1a 4 0.59 4.68 4.17 100.00
113 INT87890 Regulation of Gene_expression of Pnoc 8 0.44 2.45 7.66 100.00
114 INT87432 Regulation of Gene_expression of Il1rl1 6 0.58 4.5 6.62 100.00
115 INT42707 Gene_expression of Tbce 24 0.65 12.92 7.93 100.00
116 INT329401 Regulation of Negative_regulation of Dstn 1 0.13 1.4 0.18 100.00
117 INT329400 Negative_regulation of Dstn 1 0.13 1.34 0.17 100.00
118 INT140244 Positive_regulation of Akr1b3 3 0.69 2.8 1.12 100.00
119 INT96624 Positive_regulation of Positive_regulation of Trpv1 62 0.70 20.5 34.28 100.00
120 INT167174 Negative_regulation of Gene_expression of FSCN1 6 0.06 3.05 4.25 100.00
121 INT190093 Regulation of Gene_expression of Hivep3 1 0.49 1.06 1.32 100.00
122 INT71868 Regulation of Tenc1 9 0.52 10.73 4.09 100.00
123 INT329398 Binding of Dstn 1 0.13 1.3 0.23 100.00
124 INT237652 Positive_regulation of Sfn 3 0.49 1.17 0.27 100.00
125 INT102056 Protein_catabolism of Tenc1 14 0.84 6.29 2.14 100.00
126 INT145773 Positive_regulation of Localization of C5 1 0.49 1.15 1.06 100.00
127 INT166920 Binding of Neu1 2 0.21 2.67 0.63 100.00
128 INT42971 Binding of Hivep3 14 0.42 3.92 8.99 100.00
129 INT208540 Positive_regulation of Icmt 2 0.66 5.15 0.12 100.00
130 INT12818 Regulation of IgG-2a 9 0.37 3.23 6.07 100.00
131 INT46407 Binding of ATN1 4 0.36 5.85 1.81 100.00
132 INT244384 Binding of Slc12a5 2 0.46 2.47 1.71 100.00
133 INT86769 Positive_regulation of Gene_expression of Rbm39 11 0.25 5.6 3.8 100.00
134 INT202374 Negative_regulation of Transcription of Aqp4 2 0.37 1.34 0.69 100.00
135 INT327797 Negative_regulation of Transcription of Gfap 1 0.16 1.27 0.69 100.00
136 INT327799 Negative_regulation of Transcription of Cnp 1 0.05 1.25 0.68 100.00
137 INT327800 Transcription of Cnp 2 0.09 1.32 0.85 100.00
138 INT259762 Positive_regulation of Fbn2 4 0.05 6.74 2.55 100.00
139 INT80470 Negative_regulation of Gene_expression of Grin1 33 0.59 10.22 27.15 100.00
140 INT51690 Negative_regulation of Mnp 3 0.26 2.36 2.95 100.00
141 INT61753 Binding of HBN1 13 0.09 21.66 1.38 100.00
142 INT222241 Binding of Ccr2 5 0.42 4.09 3.71 100.00
143 INT51392 Negative_regulation of Insr 18 0.27 14.75 4.84 100.00
144 INT113736 Negative_regulation of Positive_regulation of Mc4r 1 0.08 1.11 0.93 100.00
145 INT259760 Localization of Fbn2 5 0.05 5.55 2.85 100.00
146 INT81108 Regulation of Gene_expression of LOC682801 1 0.04 0.58 0.55 100.00
147 INT71150 Binding of NGF 22 0.46 13.67 14.81 100.00
148 INT244392 Binding of Slc12a2 3 0.35 2.05 1.68 100.00
149 INT140891 Regulation of Mnp 1 0.13 0.49 1.62 100.00
150 INT247970 Regulation of CLTC 8 0.28 5.37 1.06 100.00
151 INT136203 Binding of NAMSD 1 0.01 1.23 0.15 100.00
152 INT142530 Negative_regulation of Positive_regulation of Mt2A 1 0.43 0.36 1.23 100.00
153 INT145520 Positive_regulation of Dss1 16 0.39 14.04 3.38 100.00
154 INT62523 Positive_regulation of Phosphorylation of Oprm1 11 0.53 0.75 12.51 100.00
155 INT141036 Negative_regulation of Aifm1 1 0.00 1.26 1.07 100.00
156 INT28817 Binding of TRPV4 6 0.39 3.92 2.59 100.00
157 INT259766 Positive_regulation of Localization of Fbn2 1 0.03 3.09 1.51 100.00
158 INT298013 Binding of MNS1 1 0.35 1.14 0.13 100.00
159 INT210527 Positive_regulation of Gene_expression of Tenc1 14 0.38 6.37 2.45 100.00
160 INT3440 Negative_regulation of Localization of Abat 221 0.57 33.94 180.36 100.00
161 INT287730 Positive_regulation of Gene_expression of Tpnr1 1 0.01 1.43 1.08 100.00
162 INT174844 Binding of Fig4 81 0.41 18.03 12.87 100.00
163 INT160786 Regulation of Tada1 1 0.16 0.69 1.04 100.00
164 INT47689 Positive_regulation of Ntrk2 44 0.68 16.84 19.59 100.00
165 INT117642 Regulation of Gene_expression of Grin1 18 0.53 7.09 8.08 100.00
166 INT104493 Negative_regulation of Mapk8 56 0.53 27.76 16.86 100.00
167 INT351277 Positive_regulation of Gene_expression of FMOD 1 0.10 5.79 2.25 100.00
168 INT183207 Negative_regulation of USE1 14 0.18 10.97 4 100.00
169 INT269145 Positive_regulation of Gene_expression of Mia1 1 0.34 0.98 1.23 100.00
170 INT95739 Negative_regulation of Phosphorylation of Mapk8 11 0.42 6.77 2.61 100.00
171 INT56016 Positive_regulation of Pzp 5 0.47 3.11 3.22 100.00
172 INT4880 Regulation of MME 17 0.61 7.78 8.2 100.00
173 INT107522 Regulation of Grm5 9 0.44 6.42 11.46 100.00
174 INT156296 Regulation of Trpv4 20 0.45 7.84 4.86 100.00
175 INT7717 Positive_regulation of Adra2a 62 0.70 17.68 27.32 100.00
176 INT147397 Negative_regulation of Binding of Grin2b 1 0.16 0.87 0.63 100.00
177 INT250978 Binding of FMOD 4 0.16 12.32 8.75 100.00
178 INT138388 Negative_regulation of Gene_expression of Epha4 1 0.59 1.63 1.17 100.00
179 INT305171 Binding of Man2c1 1 0.03 1.75 0 100.00
180 INT305170 Gene_expression of Man2c1 1 0.05 1.89 0 100.00
181 INT102251 Positive_regulation of Positive_regulation of Crp 24 0.58 29.62 7.5 100.00
182 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49 100.00
183 INT123306 Negative_regulation of Positive_regulation of Chrm1 3 0.32 0.72 2.63 100.00
184 INT117553 Regulation of MIF 10 0.56 12.76 8.67 100.00
185 INT136690 Regulation of Negative_regulation of Tnf 5 0.45 3.58 0.78 100.00
186 INT153277 Gene_expression of Lpar6 2 0.49 1.76 0.61 100.00
187 INT116655 Binding of NAA50 3 0.36 1.93 0.78 100.00
188 INT316709 Positive_regulation of Gene_expression of Pain1 3 0.49 2.39 1.5 100.00
189 INT77877 Regulation of P9Ehs1 13 0.38 3.31 10.04 100.00
190 INT33394 Negative_regulation of esterase 10 0.57 1.57 2.06 100.00
191 INT124556 Negative_regulation of Positive_regulation of Adora1 3 0.51 1.2 1.81 100.00
192 INT163157 Binding of BMS1 3 0.42 3.6 1.77 100.00
193 INT114524 Binding of GRIN2B 3 0.36 0.44 0.74 100.00
194 INT130610 Positive_regulation of Positive_regulation of Vipr2 1 0.10 0.26 0.61 100.00
195 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14 99.98
196 INT112427 Positive_regulation of P2rx4 27 0.68 26.29 21.31 99.98
197 INT64110 Positive_regulation of Gene_expression of Nos1 68 0.70 58.11 51.64 99.98
198 INT129686 Gene_expression of FSCN1 46 0.15 18.91 34.47 99.98
199 INT18755 Positive_regulation of Rvm 79 0.60 60 92.93 99.98
200 INT1665 Positive_regulation of Pag1 270 0.68 186.63 229.87 99.98
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