D:Neuropathy

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pChart

Disease Term
Synonyms Acquired Polyneuropathies, Acquired Polyneuropathy, Critical Illness Polyneuropathies, Critical Illness Polyneuropathy, Familial Polyneuropathies, Familial Polyneuropathy, Inherited Polyneuropathies, INHERITED POLYNEUROPATHY, Motor Polyneuropathies, MOTOR POLYNEUROPATHY, Polyneuropathies
Documents 1125
Hot Single Events 200
Hot Interactions 23

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Neuropathy. They are ordered first by their relevance to Neuropathy and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT238805 Binding of DSP and HSPB2 1 0.09 4.2 0.13 100.00
2 INT55809 Binding of Ttr and Fap 1 0.12 2.56 0.19 100.00
3 INT352627 Binding of IGHG3 and MAN2A1 1 0.00 1.48 0 100.00
4 INT262307 CAPNS1 Regulation of TAF9 1 0.04 1.23 0.33 100.00
5 INT142608 Apoe Regulation of Gene_expression of Il6 1 0.25 1.01 0.44 100.00
6 INT282129 Il10 Positive_regulation of Icam1 1 0.56 3.12 0.82 99.92
7 INT130554 Binding of TTR and Fap 1 0.02 0.72 0.07 98.20
8 INT166605 Binding of BDNF and Ntf3 1 0.16 0.46 0.28 97.00
9 INT166611 Binding of BDNF and Ngf 1 0.05 0.46 0.28 97.00
10 INT166610 Binding of BDNF and Ntf3 1 0.03 0.46 0.28 97.00
11 INT149743 Ean5 Positive_regulation of Gene_expression of P2rx2 1 0.10 1.54 1.5 96.44
12 INT13519 Binding of HLA-DQA1 and HLA-DRB4 1 0.03 0.88 0.05 95.60
13 INT166214 Binding of CTS and TTR 1 0.13 1.63 0.55 95.28
14 INT314756 IL6 Positive_regulation of Gene_expression of Crp 2 0.13 4.58 0.48 94.56
15 INT298733 INS Regulation of ACSBG1 1 0.00 0.97 0.05 91.00
16 INT298734 USE1 Regulation of ACSBG1 1 0.00 0.97 0.05 91.00
17 INT330124 Positive_regulation of Bdkrb1 Positive_regulation of RT1-O2-ps 1 0.02 1.97 1.3 87.28
18 INT85816 Binding of CEL and TTR 1 0.39 0.77 0.14 86.32
19 INT275398 Binding of ITIH4 and Htatsf1 1 0.02 5.05 2.24 82.48
20 INT275390 Binding of Ccr5 and Htatsf1 1 0.01 3.26 0.97 82.48
21 INT275386 Binding of Cxcr4 and Htatsf1 1 0.01 3.25 0.97 82.48
22 INT275407 Binding of ERVW-1 and Ccr5 1 0.00 1.74 0.46 80.32
23 INT275399 Binding of ERVW-1 and Cxcr4 1 0.00 1.73 0.46 80.32
24 INT275400 Casp3 Positive_regulation of NDRG1 1 0.00 1.36 0.18 77.44
25 INT275374 JUN Positive_regulation of NDRG1 1 0.00 1.35 0.15 77.44
26 INT153620 Binding of Ntrk1 and WNK1 1 0.02 0.85 0.12 73.88
27 INT349355 CSF2 Negative_regulation of CSTA 1 0.01 1.43 0 69.56
28 INT22926 Binding of CD79A and IGL@ 1 0.01 0.59 0.09 62.00
29 INT324926 Ptpro Positive_regulation of Bdkrb2 1 0.01 2.25 1.5 60.08
30 INT238802 Binding of Ager and Renbp 6 0.02 6.46 0.22 57.88
31 INT324927 Syt17 Positive_regulation of Bdkrb1 1 0.04 4.29 2.96 53.88
32 INT224922 Binding of FAP and TARM1 1 0.06 1.4 0.06 52.88
33 INT86997 Binding of HIVEP1 and NGF 2 0.03 1.75 1.73 50.00
34 INT194324 Binding of MPZ and MAD2L1BP 1 0.02 0.62 0.04 50.00
35 INT194333 Binding of MFN2 and Racgap1 1 0.01 0.38 0 50.00
36 INT275402 Trpv1 Regulation of Gene_expression of NDRG1 1 0.00 1.25 0.39 47.88
37 INT275406 Binding of ITIH4 and Ccr5 1 0.09 2.88 0.97 47.56
38 INT275409 Binding of ITIH4 and Cxcr4 1 0.09 2.87 0.97 47.56
39 INT305335 Olfr927-ps1 Negative_regulation of Akr1b3 1 0.02 1.6 0.17 46.64
40 INT251665 LRP5 Negative_regulation of Ache 1 0.31 0.39 0.19 40.16
41 INT310712 Gabrg1 Positive_regulation of Gene_expression of PMP22 1 0.35 0.56 0.61 39.20
42 INT310701 RPLP0 Regulation of Positive_regulation of PGR 1 0.01 0.49 0.53 34.56
43 INT314214 Mapk14 Positive_regulation of Ngf 1 0.43 1.97 1.56 31.76
44 INT266422 HMGB1 Positive_regulation of Binding of Ager 1 0.01 0.92 0.16 29.72
45 INT266376 Binding of Ager and Itgam 1 0.00 2.31 0.54 29.12
46 INT199436 Binding of Capns1 and Cysltr1 1 0.00 0.79 0.1 28.88
47 INT316112 Binding of S100B and SAE1 1 0.05 1.5 0.08 24.80
48 INT224921 Binding of TTR and TARM1 1 0.06 1.06 0 23.12
49 INT310711 Binding of RPLP0 and Gabrg1 1 0.04 0.37 0.45 18.96
50 INT308702 Binding of AQP4 and CD40LG 1 0.10 0 0 18.04
51 INT292990 SGCG Positive_regulation of Gene_expression of GABRB3 1 0.01 0.29 0.87 12.00
52 INT336341 Binding of RTCA and ELOVL1 1 0.02 2.15 0.07 11.84
53 INT292987 SGCG Positive_regulation of NCOR2 1 0.00 0.29 0.87 11.20
54 INT292988 Negative_regulation of SGCG Positive_regulation of GABRB3 1 0.01 0.3 0.89 10.40
55 INT292989 SGCG Positive_regulation of GABRB3 1 0.01 0.29 0.87 10.40
56 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49 5.00
57 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23 5.00
58 INT85743 Pdyn Positive_regulation of Oprk1 3 0.32 2.12 3.52 5.00
59 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17 5.00
60 INT114134 Penk Positive_regulation of Oprm1 2 0.24 1.48 2.68 5.00
61 INT314205 Ngf Positive_regulation of Phosphorylation of Mapk14 1 0.43 1.24 2.3 5.00
62 INT103548 Binding of TRPV1 and TRPV3 3 0.37 1.82 2.28 5.00
63 INT239037 Binding of Cd28 and Cd86 9 0.16 3.69 2.14 5.00
64 INT199486 Oprm1 Regulation of Gene_expression of Oprd1 1 0.02 0.49 1.84 5.00
65 INT314210 Ngf Regulation of Phosphorylation of Mapk14 1 0.34 0.85 1.84 5.00
66 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8 5.00
67 INT199503 ENG Positive_regulation of Oprk1 1 0.01 0.87 1.69 5.00
68 INT266391 Binding of Ager and S100a1 1 0.01 5.63 1.69 5.00
69 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68 5.00
70 INT199497 Pdyn Negative_regulation of Il1 1 0.00 0.14 1.67 5.00
71 INT199490 Penk Positive_regulation of Oprk1 1 0.03 0.87 1.64 5.00
72 INT199501 Pdyn Positive_regulation of Oprm1 1 0.01 0.86 1.63 5.00
73 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57 5.00
74 INT199494 Crh Positive_regulation of Localization of Pdyn 1 0.02 0.43 1.4 5.00
75 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38 5.00
76 INT314213 Mapk14 Positive_regulation of Agtrap 1 0.04 1.15 1.34 5.00
77 INT300864 Ngf Positive_regulation of Mapk14 2 0.60 1.38 1.32 5.00
78 INT265213 Binding of Ctla4 and Cd86 2 0.13 1.93 1.31 5.00
79 INT314211 Ngf Positive_regulation of Gene_expression of Agtrap 1 0.04 1.15 1.3 5.00
80 INT314209 Ngf Positive_regulation of Binding of Mapk14 1 0.43 1.48 1.27 5.00
81 INT314198 Mapk14 Positive_regulation of Gene_expression of Trpv1 1 0.48 1.09 1.24 5.00
82 INT314212 Mapk14 Positive_regulation of Gene_expression of Agtrap 1 0.06 1.09 1.24 5.00
83 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18 5.00
84 INT314206 Mapk14 Positive_regulation of Pax3 1 0.08 0.67 1.15 5.00
85 INT199493 Ngf Regulation of Oprd1 1 0.05 1.05 1.15 5.00
86 INT239038 Negative_regulation of Binding of Cd28 and Cd86 3 0.17 1.5 1.05 5.00
87 INT103928 Binding of Cd28 and Trav6-3 3 0.03 0.55 0.98 5.00
88 INT265210 Binding of Ctla4 and Cd28 2 0.16 1.45 0.93 5.00
89 INT314207 Ngf Negative_regulation of Phosphorylation of Mapk14 1 0.33 0.4 0.88 5.00
90 INT339318 Ngf Positive_regulation of Pik3cg 1 0.02 0.69 0.87 5.00
91 INT199499 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.8 0.86 5.00
92 INT199492 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.81 0.86 5.00
93 INT222243 Negative_regulation of Binding of Trpv1 and Ccr5 1 0.21 0.57 0.86 5.00
94 INT199487 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.86 5.00
95 INT199491 Il6 Positive_regulation of Positive_regulation of Il6 1 0.00 0.81 0.86 5.00
96 INT222244 Binding of Trpv1 and Ccr5 1 0.19 0.57 0.86 5.00
97 INT199500 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.85 5.00
98 INT199495 Il4 Positive_regulation of Positive_regulation of Oprm1 1 0.00 0.98 0.78 5.00
99 INT199476 Il4 Positive_regulation of Transcription of Stat6 1 0.01 0.97 0.77 5.00
100 INT266408 Binding of HMGB1 and Ager 1 0.01 2.57 0.76 5.00
101 INT199488 Il4 Positive_regulation of Transcription of Oprm1 1 0.01 0.84 0.73 5.00
102 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73 5.00
103 INT209250 TRPV1 Positive_regulation of Localization of DRGX 1 0.06 0.82 0.68 5.00
104 INT199489 Stat6 Positive_regulation of Oprm1 1 0.02 0.85 0.68 5.00
105 INT314199 Mapk14 Regulation of Tnf 1 0.26 0.71 0.67 5.00
106 INT222253 Binding of Cxcl10 and Fig4 1 0.09 0.66 0.65 5.00
107 INT281130 Ccl2 Regulation of Gene_expression of Ccr2 1 0.04 1.09 0.64 5.00
108 INT281134 Ccl2 Positive_regulation of Gene_expression of Ccr2 1 0.08 1.09 0.64 5.00
109 INT281122 Ccl2 Regulation of Ccr2 1 0.04 1.09 0.63 5.00
110 INT181084 Binding of S100a8 and S100a9 6 0.42 2.91 0.62 5.00
111 INT316889 Binding of Cd19 and Cr2 1 0.07 1.7 0.61 5.00
112 INT316882 Binding of Cd22 and Cr2 1 0.02 1.71 0.61 5.00
113 INT314197 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.48 1.16 0.61 5.00
114 INT281132 Binding of Ccr3 and Cxcl10 1 0.00 0.25 0.6 5.00
115 INT324925 Ros1 Positive_regulation of Bdkrb1 1 0.08 0.67 0.6 5.00
116 INT314208 Trap1 Positive_regulation of Mapk14 1 0.10 0.66 0.57 5.00
117 INT169648 IGHG3 Regulation of AQP4 3 0.02 4.63 0.55 5.00
118 INT222252 Positive_regulation of Binding of Ccr2 and Fig4 1 0.16 0.67 0.55 5.00
119 INT266381 Positive_regulation of Ager Positive_regulation of Nfkb1 1 0.00 0.77 0.55 5.00
120 INT222246 Binding of Ccr2 and Tcf21 1 0.29 0.67 0.55 5.00
121 INT222249 Positive_regulation of Binding of Ccr2 and Tcf21 1 0.39 0.67 0.55 5.00
122 INT222245 Binding of Ccr2 and Fig4 1 0.12 0.67 0.55 5.00
123 INT281124 Tcf21 Positive_regulation of Binding of Ddc 1 0.04 1.21 0.54 5.00
124 INT281129 Tcf21 Positive_regulation of Binding of Cd4 1 0.04 1.21 0.54 5.00
125 INT281152 Tcf21 Positive_regulation of Binding of ITIH4 1 0.03 1.21 0.54 5.00
126 INT281131 Tcf21 Positive_regulation of Rent1 1 0.00 1.19 0.53 5.00
127 INT327999 Binding of FPR2 and FPR3 1 0.02 3.72 0.53 5.00
128 INT275388 Binding of Lamp1 and Cxcr4 1 0.01 1.45 0.52 5.00
129 INT275403 Binding of Cxcr4 and GOLPH3 1 0.00 1.45 0.52 5.00
130 INT275387 Binding of Lamp1 and Ccr5 1 0.01 1.45 0.52 5.00
131 INT275405 Binding of GOLPH3 and Ccr5 1 0.00 1.46 0.52 5.00
132 INT132792 IL4 Positive_regulation of IL6 4 0.28 1.81 0.47 5.00
133 INT314200 Positive_regulation of Binding of Nos2 and Tnf 1 0.42 0.34 0.46 5.00
134 INT314201 Binding of Nos2 and Tnf 1 0.31 0.33 0.46 5.00
135 INT281126 Binding of Ccr2 and Cxcr4 1 0.30 0.32 0.44 5.00
136 INT266393 Binding of Ager and Fn1 1 0.00 0.82 0.39 5.00
137 INT266382 Binding of Col4a1 and Fn1 1 0.00 0.82 0.39 5.00
138 INT266397 Binding of Ager and Col4a1 1 0.00 0.81 0.38 5.00
139 INT330120 Bdkrb2 Regulation of Bdkrb1 1 0.19 1.26 0.38 5.00
140 INT281154 ITIH4 Positive_regulation of Cxcr4 1 0.09 0.71 0.37 5.00
141 INT266419 HMGB1 Positive_regulation of Ager 1 0.01 1.37 0.37 5.00
142 INT281123 Binding of Cd4 and Cxcr4 1 0.24 0.92 0.37 5.00
143 INT281128 Cd4 Positive_regulation of Cxcr4 1 0.25 0.71 0.37 5.00
144 INT281155 Binding of ITIH4 and Ddc 1 0.09 1.27 0.37 5.00
145 INT281153 Binding of ITIH4 and Cd4 1 0.10 0.91 0.37 5.00
146 INT266402 Binding of S100P and Ager 1 0.00 2.25 0.35 5.00
147 INT330122 Agt Positive_regulation of Gene_expression of Agtr1a 1 0.03 0.69 0.34 5.00
148 INT330121 Agtr1a Positive_regulation of Gene_expression of Bdkrb1 1 0.05 0.68 0.34 5.00
149 INT330119 Agt Positive_regulation of Gene_expression of Bdkrb1 1 0.37 0.63 0.34 5.00
150 INT266383 Binding of Ager and S100b 1 0.01 3.48 0.33 5.00
151 INT308701 Binding of AQP4 and DDX41 1 0.15 3.53 0.32 5.00
152 INT222251 Negative_regulation of Binding of Cxcl10 and Tcf21 1 0.23 0.34 0.32 5.00
153 INT222247 Binding of Cxcl10 and Tcf21 1 0.20 0.34 0.32 5.00
154 INT316883 Positive_regulation of Binding of Cd19 and Cd22 1 0.02 0.86 0.31 5.00
155 INT316884 Positive_regulation of Binding of Cr2 and Bcr 1 0.06 0.86 0.31 5.00
156 INT316886 Positive_regulation of Binding of Cd22 and Cr2 1 0.02 0.86 0.31 5.00
157 INT316881 Positive_regulation of Binding of Cd19 and Bcr 1 0.08 0.86 0.31 5.00
158 INT316887 Binding of Cd19 and Cd22 1 0.02 0.85 0.31 5.00
159 INT266375 S100b Positive_regulation of Ager 1 0.02 1.8 0.31 5.00
160 INT316885 Binding of Cr2 and Bcr 1 0.06 0.85 0.3 5.00
161 INT316888 Binding of Cd19 and Bcr 1 0.08 0.85 0.3 5.00
162 INT281127 Tcf21 Positive_regulation of Gene_expression of Cxcr4 1 0.08 0.42 0.3 5.00
163 INT282128 Gene_expression of Il10 Positive_regulation of Positive_regulation of Icam1 1 0.37 1.12 0.28 5.00
164 INT310255 Tlr4 Positive_regulation of Gene_expression of Cd86 2 0.18 0.06 0.27 5.00
165 INT305334 Jun Positive_regulation of Gene_expression of Tcstv1 1 0.00 1.04 0.27 5.00
166 INT308708 DDX41 Regulation of AQP4 1 0.10 2.79 0.26 5.00
167 INT132801 IL4 Positive_regulation of Localization of IL6 2 0.26 1.47 0.26 5.00
168 INT310700 PGR Regulation of Gene_expression of RPLP0 1 0.01 0.37 0.25 5.00
169 INT308815 Got1 Positive_regulation of Ldha 1 0.09 0.71 0.24 5.00
170 INT308817 Ldha Positive_regulation of Tnf 1 0.06 0.71 0.24 5.00
171 INT308818 Got1 Positive_regulation of Tnf 1 0.08 0.71 0.24 5.00
172 INT281133 Binding of Ccl2 and Cxcr4 1 0.06 0.63 0.24 5.00
173 INT266421 Binding of HMGB1 and Il1 1 0.02 0.37 0.24 5.00
174 INT308816 Gpt Positive_regulation of Tnf 1 0.08 0.72 0.24 5.00
175 INT266418 Binding of HMGB1 and Tlr4 1 0.09 0.37 0.23 5.00
176 INT316111 APC Negative_regulation of SAE1 1 0.04 1.21 0.22 5.00
177 INT275404 ITIH4 Regulation of Positive_regulation of Htatsf1 1 0.02 0.91 0.22 5.00
178 INT273024 Binding of FXYD1 and RLS 1 0.04 1.24 0.21 5.00
179 INT266405 S100b Positive_regulation of Gene_expression of TFAM 1 0.00 1.02 0.21 5.00
180 INT266380 Binding of Tlr2 and Il1 1 0.01 0.76 0.21 5.00
181 INT195212 Binding of CCR4 and Hand2 1 0.03 0.46 0.21 5.00
182 INT266401 S100b Positive_regulation of S100b Positive_regulation of Ager 1 0.01 0.96 0.21 5.00
183 INT316110 Binding of APC and SAE1 1 0.03 1.16 0.2 5.00
184 INT266423 Binding of HMGB1 and Mapk3 1 0.04 0.9 0.2 5.00
185 INT266410 Binding of HMGB1 and Mapk14 1 0.03 0.91 0.2 5.00
186 INT266416 Binding of HMGB1 and Mapk1 1 0.06 0.9 0.2 5.00
187 INT266414 Binding of HMGB1 and Mapk8 1 0.03 0.91 0.2 5.00
188 INT266404 Binding of HMGB1 and Thbd 1 0.06 0.3 0.2 5.00
189 INT353041 IL4 Positive_regulation of Localization of IL1B 1 0.02 0.99 0.16 5.00
190 INT266417 Binding of TGM2 and S100a11 1 0.01 0.86 0.16 5.00
191 INT353036 IL4 Positive_regulation of Localization of IL10 1 0.03 0.99 0.16 5.00
192 INT353040 IL4 Positive_regulation of IL8 1 0.02 0.99 0.16 5.00
193 INT353037 IL4 Positive_regulation of IL2 1 0.02 0.99 0.16 5.00
194 INT353038 IL4 Positive_regulation of Localization of IL2 1 0.02 0.99 0.16 5.00
195 INT353039 IL4 Positive_regulation of Localization of IL8 1 0.02 0.99 0.16 5.00
196 INT265215 Cd28 Regulation of Transcription of thd 1 0.00 0 0.15 5.00
197 INT310256 Tlr4 Positive_regulation of Gene_expression of H2 1 0.05 0.06 0.15 5.00
198 INT328004 Binding of CYBB and Gnb5 1 0.00 1.13 0.15 5.00
199 INT310257 Tlr4 Positive_regulation of Gene_expression of Cd40 1 0.13 0.06 0.15 5.00
200 INT266412 Binding of S100A12 and Ager 1 0.01 1.03 0.15 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Neuropathy. They are ordered first by their pain relevance and then by number of times they were reported in Neuropathy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT80498 Gene_expression of DSP 15 0.75 7.06 0.79 100.00
2 INT155838 Binding of GGT1 7 0.47 13.27 1.11 100.00
3 INT262317 Binding of TAF9 7 0.31 9.67 2.15 100.00
4 INT332200 Gene_expression of MDNS 1 0.24 2.56 0 100.00
5 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 100.00
6 INT9205 Binding of DSP 12 0.44 9.9 1.21 100.00
7 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 100.00
8 INT352629 Binding of MAN2A1 1 0.05 4.16 0.23 100.00
9 INT42152 Gene_expression of Dsp 7 0.66 4.13 1.52 100.00
10 INT9119 Negative_regulation of TAF9 4 0.42 5.21 2.16 100.00
11 INT33057 Binding of Dsp 9 0.36 4.05 2.66 100.00
12 INT252991 Regulation of TAF9 2 0.44 3.54 0.08 100.00
13 INT25771 Regulation of DSP 8 0.10 3.67 1.55 100.00
14 INT38872 Negative_regulation of Dsp 10 0.42 3.51 2.73 100.00
15 INT29956 Positive_regulation of Dsp 5 0.41 1.81 0.98 100.00
16 INT114330 Binding of MPZ 21 0.32 25.58 2.14 100.00
17 INT57115 Negative_regulation of NT5E 8 0.57 4.35 2.03 100.00
18 INT169062 Positive_regulation of Gene_expression of Pnp 6 0.49 3.6 0.21 100.00
19 INT169061 Gene_expression of Pnp 19 0.66 9.39 0.21 100.00
20 INT169060 Negative_regulation of Gene_expression of Pnp 3 0.42 0.95 0.08 100.00
21 INT86998 Regulation of HIVEP1 49 0.44 37.83 4 100.00
22 INT352628 Negative_regulation of MAN2A1 1 0.05 1.52 0 100.00
23 INT228409 Localization of DSP 5 0.73 2.39 0.11 100.00
24 INT107980 Gene_expression of Mdn1 1 0.12 0.89 0.15 100.00
25 INT128946 Regulation of PNPLA6 1 0.27 2.14 0.36 100.00
26 INT3656 Positive_regulation of Gene_expression of Ins1 74 0.54 44.94 17.36 100.00
27 INT42229 Negative_regulation of Porcn 2 0.15 1.27 0.52 100.00
28 INT163592 Localization of CISH 5 0.54 5.9 1.26 100.00
29 INT3128 Negative_regulation of PON1 30 0.59 26.19 4.57 100.00
30 INT17425 Regulation of Gene_expression of Ins1 23 0.45 18.99 5.61 100.00
31 INT6481 Binding of TNF 624 0.48 510.2 214.82 99.98
32 INT153495 Binding of Pmp22 3 0.37 2.51 0.34 99.98
33 INT123466 Binding of T2dm2 21 0.37 34.87 2.91 99.98
34 INT181322 Positive_regulation of Gene_expression of TNFAIP1 2 0.39 3.28 0 99.98
35 INT175214 Gene_expression of HSPB2 21 0.72 22.84 0.81 99.96
36 INT175225 Positive_regulation of Gene_expression of HSPB2 2 0.65 3.57 0.06 99.96
37 INT1127 Negative_regulation of IGHG3 32 0.28 21.1 7.37 99.96
38 INT81550 Binding of Pmp22 4 0.35 4.2 0.49 99.92
39 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 99.92
40 INT17349 Negative_regulation of Akr1b1 41 0.59 27.03 10.65 99.92
41 INT163613 Transcription of CSF2 16 0.60 12.98 1.62 99.92
42 INT60252 Binding of HIVEP1 59 0.32 65.12 5.06 99.92
43 INT9310 Negative_regulation of Ssr1 20 0.49 6.55 4.73 99.90
44 INT237653 Gene_expression of Sfn 6 0.59 5.54 2.26 99.90
45 INT149404 Positive_regulation of MAG 1 0.01 1.65 0.12 99.88
46 INT49643 Gene_expression of Bdkrb1 39 0.78 46.49 40.21 99.82
47 INT19330 Binding of HLA-A 99 0.48 76.26 22.85 99.82
48 INT61301 Positive_regulation of Gene_expression of Bdkrb1 7 0.68 16.95 15.44 99.82
49 INT16449 Binding of IGHG3 67 0.48 39.55 10.59 99.80
50 INT238808 Binding of HSPB2 1 0.30 2.21 0.08 99.80
51 INT2280 Negative_regulation of TNFAIP1 70 0.43 69.43 8.36 99.78
52 INT3911 Gene_expression of TNFAIP1 29 0.65 21.68 1.85 99.78
53 INT16255 Negative_regulation of Ntf3 21 0.51 12.92 11.93 99.76
54 INT30887 Negative_regulation of Ngf 56 0.59 32.96 20.86 99.76
55 INT4683 Negative_regulation of PDXK 17 0.55 12.81 4.39 99.76
56 INT257329 Gene_expression of RT1-O2-ps 5 0.02 8.38 7.25 99.76
57 INT144198 Positive_regulation of HSPB2 7 0.48 5.66 0.11 99.72
58 INT115300 Negative_regulation of Napa 7 0.23 1 2.68 99.70
59 INT45597 Negative_regulation of Epo 22 0.59 12.47 2.35 99.56
60 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 99.52
61 INT144613 Regulation of NEFL 2 0.31 1.55 0.07 99.46
62 INT164512 Regulation of MPZ 12 0.30 8.38 1.53 99.46
63 INT286054 Regulation of GJB1 1 0.08 1.04 0.07 99.46
64 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 99.44
65 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07 99.44
66 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 99.44
67 INT16150 Positive_regulation of NKG7 10 0.69 10.26 1.73 99.44
68 INT62822 Positive_regulation of Gene_expression of SELE 22 0.66 28.04 4.97 99.40
69 INT1200 Negative_regulation of Ins1 274 0.58 155.17 56.14 99.40
70 INT113777 Binding of Hmgcr 3 0.09 2.29 1.35 99.36
71 INT49284 Regulation of MYOM2 2 0.08 3.27 0.13 99.36
72 INT64982 Positive_regulation of Ifnb1 10 0.48 6.16 2.35 99.30
73 INT8106 Gene_expression of GGT1 31 0.75 18.65 6.1 99.28
74 INT37405 Positive_regulation of Cst7 7 0.49 3.32 2.99 99.28
75 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92 99.22
76 INT79928 Positive_regulation of Localization of ALB 10 0.60 8.96 1.05 99.22
77 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 99.22
78 INT2758 Binding of Dbp 36 0.44 8.3 14.47 99.20
79 INT2774 Binding of Crp 241 0.48 195.89 44.39 99.20
80 INT166599 Negative_regulation of Gene_expression of Ntf3 2 0.47 2.72 0.43 98.98
81 INT61316 Gene_expression of Coq10a 59 0.73 32.81 3.95 98.86
82 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 98.84
83 INT63035 Gene_expression of CSTA 10 0.56 11.56 0.57 98.84
84 INT102658 Negative_regulation of Gene_expression of CSF2 42 0.50 38.63 8.32 98.84
85 INT11823 Positive_regulation of GGT1 53 0.67 45.84 7.55 98.76
86 INT105200 Binding of Ntf3 6 0.31 2.46 1.67 98.76
87 INT18773 Localization of ALB 117 0.80 69.18 13.8 98.76
88 INT97871 Gene_expression of Ntf3 47 0.78 25.9 15.94 98.76
89 INT4928 Binding of Mag 9 0.26 7.62 1.42 98.74
90 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28 98.70
91 INT14726 Gene_expression of Mag 8 0.42 8.23 5 98.64
92 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 98.60
93 INT330129 Regulation of Positive_regulation of Bdkrb1 1 0.44 1.26 0.73 98.56
94 INT94127 Positive_regulation of Il18 14 0.69 14 7.47 98.52
95 INT4929 Binding of Mbp 25 0.48 18.01 9.41 98.50
96 INT63036 Negative_regulation of CSTA 4 0.36 9.42 0.22 98.48
97 INT66002 Binding of LAMC2 9 0.47 4.5 2.54 98.44
98 INT100480 Negative_regulation of Mpz 8 0.37 4.2 1.08 98.40
99 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 98.36
100 INT30517 Negative_regulation of Bdkrb1 16 0.58 16.52 16.88 98.24
101 INT101592 Gene_expression of TRPM8 82 0.78 70.61 22.89 98.20
102 INT149405 Binding of MAG 1 0.01 1.65 0.13 98.16
103 INT307615 Negative_regulation of Positive_regulation of CSF2 4 0.36 3.55 0.48 98.16
104 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 98.12
105 INT1179 Negative_regulation of Ace 157 0.59 67.03 30.46 98.08
106 INT169670 Gene_expression of PHARC 1 0.14 1.41 0.35 98.04
107 INT812 Localization of INS 1026 0.81 515.6 145.31 97.96
108 INT55310 Gene_expression of Ssr1 20 0.67 3.47 2.56 97.88
109 INT42099 Regulation of AKR1B1 2 0.45 0.46 0.39 97.84
110 INT102056 Protein_catabolism of Tenc1 14 0.84 6.29 2.14 97.82
111 INT20266 Positive_regulation of Bdkrb1 60 0.69 63.64 56.59 97.72
112 INT38056 Localization of Crp 71 0.78 53.14 17.03 97.72
113 INT55367 Localization of Dbp 18 0.70 7.43 0.38 97.72
114 INT330131 Negative_regulation of Positive_regulation of Bdkrb1 1 0.42 3.52 1.77 97.72
115 INT8959 Binding of Gnb5 17 0.40 31.38 5.1 97.68
116 INT12054 Negative_regulation of MIA3 32 0.45 23.2 6.18 97.64
117 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 97.60
118 INT262315 Negative_regulation of PLEKHM2 1 0.01 4.1 0.09 97.56
119 INT3040 Gene_expression of MIA3 81 0.24 53.61 12.62 97.52
120 INT3039 Positive_regulation of Gene_expression of MIA3 11 0.12 7.32 0.46 97.52
121 INT39212 Binding of Ttr 14 0.48 9.62 2.31 97.30
122 INT4931 Localization of IFNG 53 0.78 33.25 13.65 97.28
123 INT63164 Negative_regulation of Cst7 51 0.50 18.48 20.3 97.08
124 INT199650 Negative_regulation of Phyh 1 0.42 2.2 0.04 97.04
125 INT55309 Positive_regulation of Ssr1 20 0.46 5.97 5.74 97.00
126 INT13139 Negative_regulation of Cd4 27 0.47 17.49 6.61 96.84
127 INT139648 Localization of Ntf3 7 0.66 3.73 2.22 96.80
128 INT3034 Localization of Ngf 126 0.81 50.81 72.84 96.68
129 INT169747 Localization of AQP4 17 0.75 16.64 2.79 96.66
130 INT111262 Regulation of Gnb5 8 0.51 4.18 4.34 96.64
131 INT81551 Negative_regulation of Gene_expression of Pmp22 2 0.11 4.03 0.15 96.56
132 INT22738 Negative_regulation of DYNLL1 17 0.57 6.68 2.06 96.52
133 INT61904 Gene_expression of CST7 3 0.53 3.22 2.53 96.52
134 INT88464 Negative_regulation of CST7 11 0.31 5.33 2.17 96.52
135 INT26173 Regulation of SELS 3 0.52 3.4 0.32 96.52
136 INT62960 Gene_expression of P2rx2 149 0.77 58.31 59.16 96.44
137 INT78234 Positive_regulation of Gene_expression of P2rx2 18 0.69 12.86 12.75 96.44
138 INT67253 Gene_expression of Pmp22 4 0.33 6.48 1.79 96.24
139 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59 96.16
140 INT43707 Positive_regulation of CCBE1 11 0.07 8.22 4.86 96.08
141 INT36354 Localization of CTs 26 0.64 20.84 9.31 95.84
142 INT60699 Negative_regulation of Gene_expression of Itgax 5 0.39 1.94 1.05 95.76
143 INT153496 Negative_regulation of Pmp22 2 0.42 3.34 0.26 95.76
144 INT81553 Binding of PMP22 2 0.03 2.13 0 95.72
145 INT142735 Regulation of RLS 33 0.53 45.83 11.35 95.72
146 INT67112 Positive_regulation of fc 27 0.58 21.17 7.2 95.72
147 INT73797 Negative_regulation of Gene_expression of MIA3 14 0.10 10.65 1.25 95.68
148 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75 95.68
149 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 95.68
150 INT251661 Phosphorylation of NT5E 2 0.21 1.59 0.46 95.68
151 INT192653 Binding of Capns1 8 0.26 9.94 0.51 95.52
152 INT119446 Positive_regulation of Gnb5 6 0.58 6.47 3.72 95.48
153 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69 95.44
154 INT228540 Localization of Coq10a 12 0.63 3.5 0.3 95.44
155 INT111263 Gene_expression of Gnb5 8 0.75 8.51 3 95.44
156 INT56342 Gene_expression of TTR 34 0.78 16.5 2.05 95.44
157 INT19763 Gene_expression of CTs 69 0.78 32.92 18.87 95.44
158 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 95.40
159 INT149069 Positive_regulation of Cxcr4 24 0.68 12.21 9.54 95.32
160 INT14700 Regulation of IFNA1 111 0.45 66.16 21.52 95.28
161 INT224924 Binding of TARM1 4 0.18 3.42 0.39 95.16
162 INT151434 Positive_regulation of Ccr2 26 0.68 18.34 16.34 94.92
163 INT62678 Negative_regulation of JAG1 8 0.41 6.95 3.5 94.92
164 INT128425 Negative_regulation of TPPP 1 0.07 1.42 0.12 94.92
165 INT238807 Localization of HSPB2 1 0.75 2.27 0.04 94.72
166 INT15201 Positive_regulation of CHRM1 8 0.54 2.14 2.35 94.64
167 INT98260 Negative_regulation of Gene_expression of Bdkrb1 4 0.57 5.98 6.7 94.60
168 INT32603 Binding of MIA3 10 0.14 7.08 1.76 94.44
169 INT3926 Regulation of Bdkrb1 22 0.61 16.72 16.1 94.28
170 INT77523 Positive_regulation of ADC 14 0.63 13.81 1.81 94.24
171 INT39060 Gene_expression of Mpz 45 0.77 21.55 4.3 94.08
172 INT214 Localization of AVP 370 0.81 208.51 91.09 94.08
173 INT6110 Negative_regulation of Gene_expression of Ins1 83 0.56 60.59 16.07 94.00
174 INT56259 Positive_regulation of GGCX 3 0.69 2.08 0.35 93.96
175 INT15772 Negative_regulation of Hdlcl1 17 0.41 15.77 1.45 93.88
176 INT169669 Positive_regulation of PHARC 1 0.12 1.34 0.3 93.72
177 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 93.60
178 INT10207 Gene_expression of PADI4 22 0.75 23.49 1.74 93.56
179 INT62843 Negative_regulation of Binding of HEXA 1 0.41 0.82 0.09 93.56
180 INT62801 Gene_expression of IL1F10 1 0.59 1.02 1.24 93.52
181 INT54924 Gene_expression of RLS 67 0.62 83.2 14.25 93.28
182 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59 93.16
183 INT228545 Regulation of Coq10a 8 0.42 5.62 0.23 93.12
184 INT12950 Gene_expression of Cat 85 0.75 35.94 15.76 93.08
185 INT224366 Gene_expression of Ager 111 0.77 125.37 8.49 93.04
186 INT5622 Gene_expression of Nppa 101 0.78 49.46 25.31 93.04
187 INT13520 Binding of HLA-DRB4 30 0.42 32.65 6.74 93.04
188 INT4022 Negative_regulation of PLA2G1B 30 0.59 10.41 7.58 92.96
189 INT41729 Negative_regulation of Positive_regulation of PLA2G1B 3 0.43 2.7 1.02 92.96
190 INT144380 Gene_expression of SYNE1 12 0.58 6.99 1.55 92.96
191 INT144205 Regulation of HSPB2 2 0.43 1.74 0 92.92
192 INT120656 Localization of HMBS 3 0.16 2.6 0.23 92.92
193 INT120657 Positive_regulation of Localization of HMBS 1 0.00 0.83 0.09 92.92
194 INT62844 Binding of HEXA 2 0.36 1.45 0.23 92.84
195 INT120722 Gene_expression of TYMP 35 0.75 19.26 1.31 92.76
196 INT297115 Gene_expression of TEX33 3 0.01 5.37 1.86 92.68
197 INT297113 Positive_regulation of Gene_expression of TEX33 2 0.01 3.87 1.14 92.68
198 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19 92.68
199 INT12042 Regulation of MIA3 28 0.23 17.33 5.79 92.64
200 INT59342 Negative_regulation of NPC1 20 0.44 20.21 2.79 92.40
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