D:Noise-induced Hearing Loss

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pChart

Disease Term
Synonyms Acoustic Trauma, Hearing Loss Noise Induced, NOISE INDUCED HEARING LOSS
Documents 36
Hot Single Events 9
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Noise-induced Hearing Loss. They are ordered first by their relevance to Noise-induced Hearing Loss and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT334633 Binding of Cntnap1 and Nav1 1 0.10 1.36 1.48 5.00
2 INT334632 Binding of Kcna2 and Eae1 1 0.17 0.87 0.35 5.00
3 INT334631 Igf1r Positive_regulation of Phosphorylation of Akt1 1 0.19 0.5 0.18 5.00
4 INT334634 Binding of Igf1 and Igf1r 1 0.14 0.45 0.15 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Noise-induced Hearing Loss. They are ordered first by their pain relevance and then by number of times they were reported in Noise-induced Hearing Loss. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT190480 Positive_regulation of Localization of Ros1 11 0.34 8.29 1.81 99.16
2 INT100821 Localization of Ros1 59 0.60 45.26 11.92 98.82
3 INT6417 Negative_regulation of ABAT 49 0.51 19.6 36.81 98.68
4 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21 96.92
5 INT109558 Binding of Eae1 9 0.25 10.36 3.16 94.04
6 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 93.40
7 INT190519 Positive_regulation of Positive_regulation of Ros1 14 0.32 9.99 1.52 86.80
8 INT5489 Localization of CA2 172 0.80 39.46 33.56 83.88
9 INT330755 Protein_catabolism of Pts 1 0.13 0.29 0.05 83.32
10 INT122893 Gene_expression of Pts 4 0.10 0.97 0.61 73.76
11 INT291914 Negative_regulation of Localization of Ros1 5 0.34 1.36 0.84 54.88
12 INT14843 Gene_expression of Gabrg1 301 0.77 62.63 139.16 5.00
13 INT6323 Positive_regulation of Gabrg1 213 0.70 45.08 124.34 5.00
14 INT9516 Negative_regulation of Gabrg1 149 0.53 27.83 91.02 5.00
15 INT6585 Positive_regulation of Insrr 110 0.52 40.67 89.9 5.00
16 INT16654 Gene_expression of Insrr 138 0.46 58.96 75.68 5.00
17 INT2761 Regulation of Gabrg1 119 0.61 18.8 60.52 5.00
18 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 5.00
19 INT6034 Binding of Gabrg1 115 0.47 17.48 51.92 5.00
20 INT12471 Regulation of Insrr 52 0.35 17.8 48.31 5.00
21 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 5.00
22 INT111051 Negative_regulation of Nav1 64 0.59 25.51 47.27 5.00
23 INT60388 Gene_expression of Helt 90 0.07 19.18 41.72 5.00
24 INT118343 Positive_regulation of Eae1 121 0.39 136.06 34.87 5.00
25 INT14559 Gene_expression of Igf1 254 0.78 112 34.17 5.00
26 INT86062 Positive_regulation of Tnfrsf1a 51 0.69 40.69 26.2 5.00
27 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04 5.00
28 INT93738 Gene_expression of Tnfrsf1a 63 0.74 57.66 23.09 5.00
29 INT137767 Gene_expression of Eae1 74 0.34 89.32 20.48 5.00
30 INT33327 Positive_regulation of Gene_expression of Gabrg1 39 0.69 9.68 18.82 5.00
31 INT13244 Binding of Helt 30 0.31 4.56 18.01 5.00
32 INT112027 Gene_expression of Pik3r1 58 0.75 30.9 15.95 5.00
33 INT22143 Gene_expression of Gad1 35 0.76 14.4 15.4 5.00
34 INT11795 Negative_regulation of Helt 33 0.28 6.51 14.76 5.00
35 INT65263 Positive_regulation of Gene_expression of Igf1 61 0.69 25.69 14.49 5.00
36 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49 5.00
37 INT184844 Gene_expression of Snap25 130 0.78 14.32 12.13 5.00
38 INT148639 Gene_expression of Uchl1 30 0.59 16.76 11.54 5.00
39 INT158863 Negative_regulation of Ros1 84 0.35 40.3 10.14 5.00
40 INT120509 Gene_expression of Cat 65 0.77 50.9 9.75 5.00
41 INT141656 Regulation of Eae1 22 0.39 32.62 8.12 5.00
42 INT154094 Negative_regulation of Eae1 25 0.18 30.42 7.89 5.00
43 INT78226 Gene_expression of Mbp 43 0.75 22.14 7.79 5.00
44 INT88587 Positive_regulation of Chrna6 10 0.46 3 7.35 5.00
45 INT154093 Positive_regulation of Gene_expression of Eae1 23 0.20 26.08 5.84 5.00
46 INT15849 Gene_expression of FRTS 27 0.58 7.14 5.14 5.00
47 INT63840 Positive_regulation of Positive_regulation of Gabrg1 9 0.49 0.9 4.11 5.00
48 INT59674 Gene_expression of Chrna6 8 0.47 2.12 3.94 5.00
49 INT39884 Negative_regulation of Mbp 23 0.56 11.93 3.21 5.00
50 INT91418 Transcription of Gabrg1 11 0.62 1.12 3.16 5.00
51 INT84021 Regulation of Mbp 8 0.57 6.79 3.09 5.00
52 INT49189 Regulation of Chrna6 4 0.45 1.23 2.63 5.00
53 INT22984 Positive_regulation of FRTS 12 0.67 5.24 2.25 5.00
54 INT59673 Negative_regulation of Chrna6 8 0.30 2.31 2.16 5.00
55 INT22342 Gene_expression of Gstp2 5 0.38 3.98 1.86 5.00
56 INT112270 Negative_regulation of Cntnap1 4 0.57 1.74 1.76 5.00
57 INT8345 Negative_regulation of FRTS 10 0.42 2.8 1.7 5.00
58 INT14514 Regulation of FRTS 10 0.44 2.39 1.56 5.00
59 INT164532 Regulation of Gene_expression of Eae1 4 0.18 2.53 1.5 5.00
60 INT135959 Negative_regulation of Gene_expression of Igf1 37 0.56 21.16 1.41 5.00
61 INT90491 Binding of Igf1 25 0.44 9.75 1.36 5.00
62 INT57709 Positive_regulation of Gstp2 2 0.60 0.87 1.1 5.00
63 INT139150 Regulation of Psd 4 0.35 0.28 0.98 5.00
64 INT67320 Positive_regulation of CAPRIN2 11 0.48 2.73 0.94 5.00
65 INT14866 Positive_regulation of SGPL1 3 0.60 0.55 0.91 5.00
66 INT204825 Negative_regulation of Plp1 3 0.33 2.96 0.87 5.00
67 INT19950 Gene_expression of Abo 13 0.16 4.72 0.84 5.00
68 INT202361 Gene_expression of Mef2c 28 0.78 5.53 0.67 5.00
69 INT218605 Negative_regulation of Kcna2 2 0.41 1.68 0.55 5.00
70 INT189634 Regulation of DCN 3 0.25 1.69 0.49 5.00
71 INT206996 Negative_regulation of Slc10a7 5 0.21 0.38 0.49 5.00
72 INT27115 Binding of Mbp 8 0.31 3.01 0.48 5.00
73 INT294370 Negative_regulation of Niacr1 3 0.24 2.54 0.42 5.00
74 INT245361 Regulation of Plp1 1 0.35 1.15 0.38 5.00
75 INT309839 Binding of Nlrp1a 5 0.29 1.95 0.38 5.00
76 INT334624 Positive_regulation of Gene_expression of Kcna2 1 0.49 0.86 0.35 5.00
77 INT334621 Gene_expression of Kcna2 1 0.65 0.86 0.34 5.00
78 INT334623 Negative_regulation of Gene_expression of Kcna2 1 0.41 0.86 0.34 5.00
79 INT294378 Regulation of Epha3 1 0.35 0 0.31 5.00
80 INT183394 Localization of Mbp 8 0.54 3.17 0.3 5.00
81 INT187465 Localization of Ptprc 8 0.62 3.71 0.25 5.00
82 INT294366 Gene_expression of Kcnd2 1 0.73 0.09 0.25 5.00
83 INT151391 Binding of Kcnip4 2 0.35 0.18 0.24 5.00
84 INT250517 Phosphorylation of Igf1r 5 0.79 1.21 0.21 5.00
85 INT286068 Positive_regulation of Positive_regulation of Igf1 2 0.40 1.03 0.16 5.00
86 INT294371 Positive_regulation of Phosphorylation of Mef2a 1 0.42 0 0.1 5.00
87 INT294376 Phosphorylation of Psd 1 0.34 0 0.1 5.00
88 INT294377 Regulation of Phosphorylation of Psd 1 0.15 0 0.1 5.00
89 INT294379 Phosphorylation of Mef2a 1 0.56 0 0.1 5.00
90 INT48686 Localization of Plp1 7 0.07 0.71 0.09 5.00
91 INT246529 Localization of Gstp2 3 0.41 3.63 0.09 5.00
92 INT294368 Gene_expression of Gm9803 1 0.01 0 0.08 5.00
93 INT294375 Gene_expression of Gm4040 1 0.01 0 0.08 5.00
94 INT290699 Negative_regulation of SGPL1 1 0.37 0 0 5.00
95 INT290700 Transcription of SGPL1 1 0.59 0 0 5.00
96 INT294367 Positive_regulation of Negative_regulation of Slc10a3 1 0.14 0.12 0 5.00
97 INT294369 Negative_regulation of Positive_regulation of Slc10a3 1 0.12 0.26 0 5.00
98 INT294372 Positive_regulation of Slc10a3 2 0.14 0.34 0 5.00
99 INT294373 Positive_regulation of Positive_regulation of Slc10a3 3 0.14 0.53 0 5.00
100 INT294374 Negative_regulation of Slc10a3 1 0.12 0.07 0 5.00
101 INT334622 Negative_regulation of Regulation of Mbp 1 0.35 0.94 0 5.00
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