D:Non-small-cell Lung Cancer

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Disease Term
Synonyms Carcinoma Non Small Cell Lung, Carcinomas Non Small Cell Lung, LUNG CARCINOMA NON SMALL CELL, LUNG CARCINOMAS NON SMALL CELL, Non Oat Cell Lung Cancer, Non Oat Cell Lung Cancers, Non Small Cell Lung Cancer, NON SMALL CELL LUNG CANCERS, Non Small Cell Lung Carcinoma, Non Small Cell Lung Carcinomas, NONSMALL CELL LUNG CANCER
Documents 553
Hot Single Events 200
Hot Interactions 42

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Non-small-cell Lung Cancer. They are ordered first by their relevance to Non-small-cell Lung Cancer and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT274471 IL12A Negative_regulation of Gene_expression of IL10 1 0.02 0.99 0.1 98.72
2 INT199863 Gopc Negative_regulation of Jun 1 0.03 1.07 0 97.68
3 INT199858 Gopc Negative_regulation of Phosphorylation of Jun 1 0.03 1.08 0 97.68
4 INT199860 Gopc Negative_regulation of Positive_regulation of Mapk8 1 0.07 1.07 0 97.68
5 INT353125 Negative_regulation of Binding of VEGFA and Kdr 1 0.04 5.92 0 96.72
6 INT277663 Binding of EGFR and TTPA 1 0.05 0.41 0 96.52
7 INT199862 Mapk8 Negative_regulation of Jun 1 0.05 1.06 0 95.76
8 INT302131 Negative_regulation of SOD2 Regulation of BAK1 1 0.09 1.22 0.07 95.64
9 INT302289 Negative_regulation of Birc5 Regulation of BAK1 1 0.20 1.22 0.07 95.64
10 INT302290 Birc5 Regulation of BAK1 1 0.21 1.22 0.07 95.44
11 INT302128 SOD2 Regulation of BAK1 1 0.09 1.22 0.07 95.44
12 INT185353 Eri1 Negative_regulation of Transcription of Egfr 1 0.01 0.5 0 94.80
13 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34 94.56
14 INT221815 PPARA Negative_regulation of PTEN 1 0.15 0.5 0.05 94.40
15 INT315194 Binding of SFRP1 and Slc10a1 1 0.02 8.85 0 93.44
16 INT197547 Binding of PTS and KEAP1 1 0.08 1.23 0 93.16
17 INT75769 Egf Positive_regulation of Cpox 1 0.26 0.76 0.31 93.12
18 INT175398 Binding of ERBB2 and VEGFA 2 0.16 1.34 0.13 92.40
19 INT175401 Binding of EGFR and VEGFA 2 0.13 1.49 0.13 92.40
20 INT297614 ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.56 0 90.88
21 INT297613 Negative_regulation of ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.66 0 90.88
22 INT233848 Zeb1 Positive_regulation of Snai1 1 0.07 0.58 0.04 90.88
23 INT233852 Twist1 Positive_regulation of Snai1 1 0.02 0.58 0.04 90.88
24 INT315829 Binding of EGFR and TKT 1 0.03 1.14 0.12 90.64
25 INT233849 Twist1 Positive_regulation of Snai2 1 0.07 0.58 0.04 90.56
26 INT233853 Zeb1 Positive_regulation of Snai2 1 0.09 0.58 0.04 90.56
27 INT233850 Zeb1 Positive_regulation of Itk 1 0.04 0.58 0.04 89.96
28 INT233851 Twist1 Positive_regulation of Zeb1 1 0.06 0.58 0.04 89.96
29 INT244116 ELAVL3 Negative_regulation of MUC1 1 0.09 3.41 0.15 89.68
30 INT233854 Twist1 Positive_regulation of Itk 1 0.03 0.58 0.04 89.56
31 INT286768 Binding of Trp53 and Tusc2 1 0.07 1.1 0.05 88.16
32 INT286767 Binding of Abl1 and Tusc2 1 0.54 1.04 0.03 87.84
33 INT197552 GSTK1 Positive_regulation of NQO1 1 0.09 1.06 0 87.04
34 INT185357 Eri1 Negative_regulation of Gene_expression of Egfr 1 0.01 0.57 0 86.72
35 INT302883 Binding of TXN and Alb 1 0.06 4.13 0.1 83.92
36 INT302882 Positive_regulation of Binding of TXN and Alb 1 0.05 1.51 0 83.92
37 INT233855 Binding of Ppara and Mapk7 1 0.09 0.9 0.05 83.84
38 INT291329 Binding of NOTCH1 and CERS1 1 0.06 1.42 0 81.52
39 INT197576 Loh1 Positive_regulation of NFE2L2 1 0.49 1.1 0 81.32
40 INT240016 Binding of IL6 and POMT1 1 0.03 0.99 0.11 81.04
41 INT189956 TP53 Positive_regulation of Gene_expression of Pttg1 1 0.06 1.21 0 80.92
42 INT340726 SERPINB1 Regulation of CSPG5 1 0.00 0.35 0.05 80.80
43 INT291330 Binding of ENO1 and NOTCH1 1 0.03 1.33 0 78.80
44 INT199576 Raf1 Negative_regulation of Akt1 1 0.00 0.79 0 77.92
45 INT199577 Tnk1 Negative_regulation of Akt1 1 0.00 0.79 0 77.92
46 INT199582 Braf Negative_regulation of Akt1 1 0.00 0.79 0 77.92
47 INT199579 Tnk1 Negative_regulation of Raf1 1 0.01 0.78 0 77.92
48 INT199578 Tnk1 Negative_regulation of Braf 1 0.01 0.78 0 77.92
49 INT291333 Binding of CSHL1 and NOTCH1 1 0.05 1.16 0 76.48
50 INT101810 Binding of NFE2L2 and KEAP1 7 0.53 4.12 0.29 74.88
51 INT297376 Binding of RARS and Rxra 1 0.01 3.27 0.24 72.84
52 INT189957 Binding of LDHA and Pttg1 1 0.05 0.35 0.08 68.24
53 INT316975 ARMC9 Regulation of PEAK1 1 0.00 0.07 0 68.08
54 INT315187 Binding of SFRP1 and COPD 1 0.01 4.47 0 68.08
55 INT274469 IL12A Positive_regulation of Gene_expression of IL6 1 0.04 1.39 0.06 67.44
56 INT145661 Ptger2 Positive_regulation of Gene_expression of VEGFA 4 0.27 2.73 0.6 65.48
57 INT134454 EGF Positive_regulation of EGFR 3 0.56 1.32 0.88 65.36
58 INT274060 EGF Positive_regulation of EGFR Positive_regulation of TKT 1 0.08 1 0 65.36
59 INT274061 EGF Positive_regulation of EGFR Positive_regulation of TXK 1 0.06 1 0 65.36
60 INT274062 EGF Positive_regulation of EGFR Positive_regulation of Positive_regulation of TXK 1 0.06 1 0 65.36
61 INT274475 IL12A Regulation of Gene_expression of IL6 1 0.04 0.68 0 65.12
62 INT236936 Ppara Positive_regulation of Mapk1 1 0.09 0.64 0.07 64.72
63 INT323506 ROS1 Positive_regulation of Phosphorylation of EGFR 1 0.32 0.69 0 61.48
64 INT328932 TRGC1 Regulation of C2 1 0.03 0.92 0.31 61.44
65 INT277835 EPO Positive_regulation of Localization of VEGFA 1 0.03 1.36 0.08 60.56
66 INT315161 Egfr Negative_regulation of Erbb2 1 0.36 0.83 0 59.28
67 INT315167 Egfr Negative_regulation of Mapk3 1 0.04 0.83 0 59.28
68 INT315169 Egfr Negative_regulation of PCNA 1 0.03 0.84 0 59.28
69 INT315160 Egfr Negative_regulation of Myc 1 0.45 0.84 0 59.28
70 INT315162 Egfr Negative_regulation of Akt1 1 0.17 0.83 0 59.28
71 INT315163 Erbb2 Negative_regulation of Akt1 1 0.17 0.83 0 59.08
72 INT315159 Erbb2 Negative_regulation of Myc 1 0.43 0.84 0 59.08
73 INT315166 Erbb2 Negative_regulation of Egfr 1 0.36 0.83 0 59.08
74 INT315168 Erbb2 Negative_regulation of Mapk3 1 0.03 0.83 0 59.08
75 INT315170 Erbb2 Negative_regulation of PCNA 1 0.03 0.84 0 59.08
76 INT236938 Binding of Akt1 and SPNS1 1 0.00 0.72 0.06 59.04
77 INT258529 Binding of JAG1 and NOTCH1 3 0.06 2.44 0 58.72
78 INT258528 Binding of NOTCH1 and DLL1 2 0.07 1.6 0 58.00
79 INT276904 Regulation of Binding of Egfr and Prkdc 1 0.03 0.42 0 56.48
80 INT276905 Binding of Egfr and Prkdc 1 0.04 0.41 0 56.48
81 INT328851 Binding of PTGS2 and ZNF434 1 0.00 0.7 0.14 55.60
82 INT258521 EGFR Positive_regulation of MMP2 1 0.39 0.91 0.24 55.28
83 INT258565 EGFR Positive_regulation of Meta 1 0.39 0.89 0.23 55.28
84 INT286769 Tusc2 Regulation of Foxm1 1 0.02 1.55 0.15 55.24
85 INT199859 Gem Positive_regulation of Phosphorylation of Mapk8 1 0.10 0.67 0 53.36
86 INT199861 Xiap Regulation of Gopc 1 0.07 0.46 0 50.00
87 INT340727 Binding of ATP5G3 and CSPG5 1 0.01 2.03 0.06 49.60
88 INT340741 Binding of ATP5G3 and Gma3 1 0.00 0.96 0.03 49.60
89 INT197545 KEAP1 Regulation of NFE2L2 3 0.49 0.8 0 46.88
90 INT244461 CS Positive_regulation of ESR1 1 0.06 1.15 0.05 43.92
91 INT187640 Binding of EGFR and KLF1 3 0.01 2.54 0 43.68
92 INT320267 CCNA2 Positive_regulation of CDK1 1 0.12 1.08 0.08 32.76
93 INT280568 MRAS Positive_regulation of RAF1 1 0.01 0.7 0 31.04
94 INT345506 Binding of EGFR and FNDC3A 1 0.00 0.08 0 30.32
95 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 29.84
96 INT280566 Binding of ARAF and BCL2 1 0.02 0.69 0 26.24
97 INT199581 Braf Negative_regulation of Phosphorylation of tk 1 0.05 0.6 0 26.00
98 INT199580 Braf Negative_regulation of Phosphorylation of Mdk 1 0.11 0.6 0 26.00
99 INT236937 Map2k1 Negative_regulation of Ppara Positive_regulation of Itk 1 0.00 0.31 0 22.24
100 INT236933 Ppara Positive_regulation of Itk 1 0.01 0.31 0 22.24
101 INT236935 Negative_regulation of Ppara Positive_regulation of Itk 1 0.01 0.31 0 22.24
102 INT341632 Binding of EGFR and FOXM1 1 0.02 0.56 0 22.08
103 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27 20.32
104 INT197546 NFE2L2 Regulation of Gene_expression of ABCC2 1 0.17 0.72 0.04 17.44
105 INT226337 Binding of IL10 and IL10RA 2 0.24 2.51 0.85 14.84
106 INT258526 IPMK Negative_regulation of BRAF 1 0.01 1.11 0 14.48
107 INT258524 IPMK Negative_regulation of KDR 2 0.00 1.98 0 13.68
108 INT258525 IPMK Negative_regulation of DDR1 2 0.00 1.97 0 13.12
109 INT186712 INCENP Positive_regulation of PPARA 1 0.01 1.05 0.08 12.60
110 INT186729 Csf2 Positive_regulation of PPARA 1 0.06 1.04 0.08 11.64
111 INT174503 Binding of HLA-B and KIR3DL1 6 0.37 3.48 1.61 11.56
112 INT328936 Binding of HLA-B and KIR3DS1 1 0.25 0.7 0.48 10.36
113 INT197553 Binding of NFE2L2 and LILRA3 1 0.03 0.43 0.06 8.88
114 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61 8.48
115 INT145152 Binding of EGF and EGFR 4 0.15 2.45 0.19 7.60
116 INT277664 Negative_regulation of Binding of EGF and EGFR 1 0.18 0.5 0 7.60
117 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 5.00
118 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68 5.00
119 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27 5.00
120 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18 5.00
121 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 5.00
122 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
123 INT306823 Binding of E2F4 and GOPC 1 0.06 0.23 0.91 5.00
124 INT118288 EGF Positive_regulation of Phosphorylation of EGFR 9 0.54 3.85 0.9 5.00
125 INT306831 Positive_regulation of Binding of E2F4 and NOLC1 1 0.10 0.46 0.85 5.00
126 INT306826 Binding of E2F4 and NOLC1 1 0.08 0.41 0.84 5.00
127 INT282286 Akt1 Positive_regulation of Pak1 1 0.15 0.24 0.61 5.00
128 INT156667 Gh Positive_regulation of Gene_expression of Igf1 6 0.28 0.88 0.56 5.00
129 INT282284 Cpox Positive_regulation of Akt1 1 0.02 0.47 0.54 5.00
130 INT282282 Ptger2 Positive_regulation of Akt1 1 0.03 0.47 0.54 5.00
131 INT210878 Binding of FLT1 and HBM 1 0.06 0.83 0.5 5.00
132 INT282285 Cpox Regulation of Gene_expression of Ptger2 1 0.00 0.84 0.5 5.00
133 INT186713 IK Positive_regulation of Gene_expression of NOS1 1 0.00 0.55 0.49 5.00
134 INT306828 Binding of E2F2 and E2F3 1 0.20 0.15 0.46 5.00
135 INT306824 Binding of E2F1 and E2F2 1 0.15 0.15 0.46 5.00
136 INT108332 EGF Positive_regulation of Phosphorylation of MAPK1 5 0.48 1.85 0.45 5.00
137 INT186711 IK Positive_regulation of Localization of IL8 1 0.00 0.39 0.44 5.00
138 INT328933 Binding of KIR2DS4 and TRGC1 1 0.09 0.76 0.41 5.00
139 INT328934 Binding of C2 and KIR2DS4 1 0.11 0.76 0.41 5.00
140 INT328935 Binding of HLA-G and KIR2DS4 1 0.39 0.75 0.41 5.00
141 INT235432 Ppara Negative_regulation of Gene_expression of Cpox 1 0.01 1 0.37 5.00
142 INT306830 E2F2 Regulation of C1orf61 1 0.02 0.48 0.36 5.00
143 INT172213 Binding of BAX and BCL2L1 3 0.22 4.02 0.35 5.00
144 INT297352 KLF2 Regulation of PPARA 1 0.12 1.31 0.35 5.00
145 INT306822 Binding of E2F2 and GOPC 1 0.05 0.53 0.35 5.00
146 INT333893 Negative_regulation of HDAC9 Negative_regulation of Gene_expression of TNF 1 0.09 1.03 0.34 5.00
147 INT297351 EWSR1 Positive_regulation of PPARA 1 0.41 1.81 0.33 5.00
148 INT235430 Il13 Positive_regulation of Gene_expression of Olr1 1 0.00 2.12 0.33 5.00
149 INT330377 Positive_regulation of Binding of TLR2 and TLR9 1 0.09 2.79 0.32 5.00
150 INT330381 Binding of TLR2 and TLR9 1 0.07 2.77 0.32 5.00
151 INT330389 Positive_regulation of Binding of TLR2 and TLR8 1 0.08 2.78 0.32 5.00
152 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31 5.00
153 INT330383 Binding of TLR2 and TLR3 1 0.07 2.77 0.31 5.00
154 INT330378 Positive_regulation of Binding of TLR2 and TLR3 1 0.10 2.78 0.31 5.00
155 INT330387 Binding of TLR2 and TLR8 1 0.06 2.77 0.31 5.00
156 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3 5.00
157 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3 5.00
158 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3 5.00
159 INT101813 KEAP1 Negative_regulation of NFE2L2 3 0.47 1.63 0.28 5.00
160 INT320794 Binding of VEGFA and Flt4 4 0.08 3.04 0.27 5.00
161 INT109538 Lox Negative_regulation of Transcription of VEGFA 1 0.30 0.69 0.26 5.00
162 INT245072 PPARA Regulation of Gene_expression of CXCR4 1 0.07 0.68 0.26 5.00
163 INT109539 Lox Negative_regulation of VEGFA 1 0.40 0.68 0.25 5.00
164 INT302169 PTGER2 Positive_regulation of DYNC1LI1 1 0.02 1.51 0.25 5.00
165 INT333892 TNF Positive_regulation of Gene_expression of HDAC1 1 0.09 0.46 0.23 5.00
166 INT354926 IL6 Regulation of Gene_expression of ALB 1 0.14 1.3 0.23 5.00
167 INT354924 IL6 Positive_regulation of Gene_expression of ALB 1 0.26 1.3 0.23 5.00
168 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23 5.00
169 INT330382 IFNA1 Positive_regulation of Gene_expression of IL10 1 0.06 0.83 0.21 5.00
170 INT271852 Ngf Positive_regulation of Gene_expression of tf 1 0.34 1.36 0.21 5.00
171 INT271853 Ngf Positive_regulation of Gene_expression of Egr1 1 0.53 1.36 0.21 5.00
172 INT330371 Binding of TLR3 and Ifx 1 0.17 1.12 0.2 5.00
173 INT279965 STAT3 Regulation of Transcription of BCL2L1 1 0.10 2.31 0.19 5.00
174 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19 5.00
175 INT193214 Binding of PTGER2 and PTGER4 2 0.08 2.51 0.18 5.00
176 INT298196 EGFR Positive_regulation of PIK3CD 1 0.04 0.65 0.18 5.00
177 INT298192 EGFR Positive_regulation of AKT1 1 0.10 0.65 0.18 5.00
178 INT209581 Twist1 Positive_regulation of Gene_expression of VEGFA 6 0.06 7.86 0.16 5.00
179 INT330388 Binding of PTPRC and TLR2 1 0.00 1.19 0.16 5.00
180 INT302146 CDKN2A Regulation of CDKN1B 1 0.11 0.51 0.14 5.00
181 INT274474 IL12A Regulation of Gene_expression of VEGFA 1 0.04 0.36 0.14 5.00
182 INT302144 CDKN2A Regulation of CDKN1A 1 0.11 0.51 0.14 5.00
183 INT274472 IL12A Negative_regulation of Gene_expression of FGF2 1 0.02 0.36 0.14 5.00
184 INT274473 IL12A Regulation of Gene_expression of FGF2 1 0.02 0.36 0.14 5.00
185 INT330370 Positive_regulation of Binding of IL10 and Il4 1 0.01 0.47 0.13 5.00
186 INT258016 AGTR1 Positive_regulation of EGFR 1 0.15 1.24 0.13 5.00
187 INT302156 AKT1 Positive_regulation of E2F2 1 0.02 0.88 0.13 5.00
188 INT330369 Binding of IL10 and Il4 1 0.01 0.47 0.13 5.00
189 INT308004 Rsph1 Positive_regulation of Mapk14 1 0.02 0.61 0.12 5.00
190 INT258527 Binding of BRAF and RET 1 0.21 1.49 0.11 5.00
191 INT199583 HIF1A Positive_regulation of Gene_expression of Vhl 1 0.26 1.39 0.11 5.00
192 INT199595 FGF7 Positive_regulation of Transcription of TNF 1 0.40 0.58 0.11 5.00
193 INT302161 AKT1 Negative_regulation of CASP9 1 0.03 0.87 0.11 5.00
194 INT312305 Binding of HIF1A and Positive_regulation of Transcription of VEGFA 1 0.17 2.8 0.1 5.00
195 INT258014 Binding of ANGPT2 and RASGRP1 1 0.00 1.58 0.1 5.00
196 INT302287 Twist1 Positive_regulation of Positive_regulation of PTGER2 1 0.03 1.16 0.1 5.00
197 INT302288 Twist1 Positive_regulation of PTGER2 1 0.03 1.16 0.1 5.00
198 INT330380 CD40 Regulation of Gene_expression of IFNA1 1 0.17 0.78 0.1 5.00
199 INT258522 Binding of DDR1 and RET 1 0.03 1.05 0.1 5.00
200 INT258018 Binding of AGT and RASGRP1 1 0.00 1.59 0.1 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Non-small-cell Lung Cancer. They are ordered first by their pain relevance and then by number of times they were reported in Non-small-cell Lung Cancer. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT113705 Gene_expression of Egfr 228 0.78 149.05 7.59 100.00
2 INT54565 Binding of SCLC1 12 0.31 20.41 0.81 100.00
3 INT163832 Negative_regulation of Gene_expression of EGFR 50 0.59 39.71 3.45 100.00
4 INT82797 Transcription of CDKN1A 11 0.69 8.01 0.32 100.00
5 INT172570 Positive_regulation of SCLC1 5 0.67 6.27 1.5 100.00
6 INT32431 Gene_expression of HTC2 17 0.75 9.72 1.93 100.00
7 INT65472 Binding of HLA-G 9 0.36 6.06 2.6 100.00
8 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 99.96
9 INT189948 Gene_expression of Pttg1 106 0.76 104.68 1.41 99.96
10 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 99.96
11 INT112124 Positive_regulation of Egfr 71 0.70 47.82 5.61 99.96
12 INT13907 Gene_expression of SCLC1 16 0.59 16.58 1.89 99.96
13 INT20627 Regulation of Gene_expression of LDHA 5 0.42 4.07 0.92 99.96
14 INT101820 Negative_regulation of KEAP1 20 0.58 18.79 0.19 99.92
15 INT13416 Positive_regulation of Pthlh 19 0.60 14.78 3.74 99.92
16 INT11157 Binding of EGF 88 0.48 53.73 21.25 99.88
17 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 99.88
18 INT120563 Positive_regulation of Gene_expression of Egfr 56 0.70 46.19 1.82 99.86
19 INT120562 Negative_regulation of Egfr 108 0.59 79.38 3.11 99.84
20 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 99.84
21 INT144430 Gene_expression of Erbb2 137 0.77 103.87 8.66 99.84
22 INT185350 Negative_regulation of Gene_expression of Egfr 24 0.59 13.21 0.35 99.84
23 INT79685 Positive_regulation of Gene_expression of Pparg 17 0.70 14.63 11.03 99.84
24 INT67608 Gene_expression of Pparg 41 0.78 25.09 19.53 99.84
25 INT49440 Localization of Cpox 27 0.53 11.26 5.79 99.84
26 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3 99.84
27 INT78913 Positive_regulation of Gene_expression of ABCC1 22 0.67 5.95 5.82 99.84
28 INT120073 Positive_regulation of Itk 34 0.44 23.45 5.09 99.84
29 INT197563 Regulation of KEAP1 10 0.56 3.18 0.11 99.84
30 INT172558 Positive_regulation of Cdh1 11 0.49 8.92 0.42 99.84
31 INT90875 Negative_regulation of CCND1 31 0.42 26.22 2.66 99.82
32 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07 99.82
33 INT181211 Gene_expression of Magea3 1 0.02 0.81 0.06 99.76
34 INT14737 Gene_expression of FN1 117 0.78 78.74 18.99 99.68
35 INT144428 Positive_regulation of Gene_expression of Erbb2 41 0.69 41.4 4.13 99.68
36 INT233857 Positive_regulation of Binding of SCLC1 1 0.06 2.37 0.06 99.68
37 INT57272 Negative_regulation of Gene_expression of FN1 16 0.43 11.42 1.93 99.68
38 INT81574 Positive_regulation of SIL1 21 0.67 10.85 0.31 99.68
39 INT340730 Gene_expression of Gma3 1 0.01 6.67 0.21 99.62
40 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.60
41 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.60
42 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 99.60
43 INT274481 Gene_expression of IL12RB2 7 0.75 3.14 0.46 99.60
44 INT199004 Gene_expression of ARMC9 43 0.58 17.72 1.32 99.60
45 INT97479 Gene_expression of Tks 11 0.52 3.66 2.44 99.60
46 INT100139 Positive_regulation of Gene_expression of PPARA 160 0.63 97.78 14.53 99.60
47 INT172479 Positive_regulation of NFE2L2 74 0.70 35.22 0.79 99.58
48 INT144534 Localization of Gem 3 0.37 1.62 0.41 99.58
49 INT304081 Gene_expression of Nde1 1 0.18 1.18 0 99.56
50 INT141833 Gene_expression of WNT1 14 0.75 10.57 2.1 99.52
51 INT2037 Negative_regulation of EGF 30 0.59 15.05 6.81 99.52
52 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 99.50
53 INT101857 Negative_regulation of BCL2L1 22 0.57 23.56 3.95 99.50
54 INT259061 Negative_regulation of Regulation of TP53 2 0.10 2.23 0.03 99.50
55 INT240020 Regulation of Binding of IL6 4 0.36 4.38 0.46 99.44
56 INT86437 Binding of IL6 154 0.48 121.22 29.3 99.44
57 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 99.44
58 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23 99.44
59 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55 99.42
60 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 99.40
61 INT122195 Regulation of Localization of VEGFA 13 0.57 10.61 1.92 99.40
62 INT25381 Localization of Csf2 62 0.76 47.48 9.03 99.38
63 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 99.36
64 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 99.36
65 INT18192 Regulation of Gene_expression of Alb 16 0.44 9.38 3.57 99.36
66 INT615 Regulation of Alb 66 0.62 33.43 15.33 99.36
67 INT189944 Negative_regulation of Gene_expression of Pttg1 4 0.42 4.53 0 99.34
68 INT316978 Positive_regulation of PEAK1 7 0.01 1.71 0.05 99.32
69 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7 99.30
70 INT184651 Gene_expression of RRM1 6 0.48 3.46 0.15 99.28
71 INT189945 Localization of Pttg1 3 0.73 3.02 0.16 99.28
72 INT185352 Regulation of Gene_expression of Egfr 5 0.62 2.33 0.16 99.28
73 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 99.24
74 INT124375 Gene_expression of Wnt2 67 0.56 38.03 4.67 99.24
75 INT316976 Negative_regulation of PEAK1 1 0.01 1.14 0.08 99.24
76 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64 99.24
77 INT199681 Gene_expression of SERPINA5 13 0.36 15.42 1.25 99.24
78 INT193823 Positive_regulation of Gene_expression of TP63 7 0.18 7.74 1.57 99.24
79 INT124373 Positive_regulation of Gene_expression of Wnt2 14 0.42 8.28 0.6 99.24
80 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 99.22
81 INT94028 Regulation of Twist1 37 0.44 22.41 5.33 99.20
82 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 99.20
83 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 99.16
84 INT114246 Positive_regulation of Negative_regulation of EGFR 13 0.49 8.67 0.7 99.16
85 INT226288 Negative_regulation of SFRP1 6 0.43 4.45 0 99.16
86 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39 99.12
87 INT199845 Positive_regulation of Gem 2 0.25 1.14 0.2 99.12
88 INT189946 Positive_regulation of Gene_expression of Pttg1 14 0.68 23.72 0.38 99.08
89 INT123877 Negative_regulation of ABL1 40 0.57 27.94 1.17 99.06
90 INT189949 Regulation of Gene_expression of Pttg1 1 0.60 6.84 0 99.04
91 INT175423 Positive_regulation of TSC1 25 0.36 21.81 0.45 99.02
92 INT286756 Positive_regulation of Tusc2 1 0.69 2.51 0.16 99.02
93 INT62441 Gene_expression of ABCC1 56 0.78 21.01 12.93 98.96
94 INT105958 Negative_regulation of Gene_expression of HTC2 5 0.12 3.46 0.07 98.96
95 INT194803 Positive_regulation of Gene_expression of GADD45A 4 0.36 1.8 0.08 98.96
96 INT197562 Positive_regulation of KEAP1 16 0.63 6.78 0.08 98.88
97 INT221830 Negative_regulation of Transcription of CCND1 3 0.18 2.15 0.03 98.88
98 INT139807 Gene_expression of Braf 7 0.51 8.78 3.34 98.84
99 INT171361 Regulation of Egfr 16 0.62 8.36 0.81 98.84
100 INT8068 Gene_expression of RASGRP1 29 0.54 15.1 1.37 98.80
101 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47 98.80
102 INT8096 Positive_regulation of Gene_expression of EGF 21 0.69 13.43 3.47 98.80
103 INT131378 Negative_regulation of FN1 20 0.35 33.98 5.85 98.80
104 INT27739 Positive_regulation of EGF 49 0.70 28.31 13.68 98.80
105 INT328950 Binding of KIR2DS5 1 0.37 6.31 2.63 98.76
106 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 98.72
107 INT39046 Positive_regulation of PTGER1 28 0.69 18.18 13.21 98.72
108 INT193114 Positive_regulation of Positive_regulation of Birc5 1 0.45 0.33 0.17 98.72
109 INT113348 Negative_regulation of Binding of TP53 2 0.28 1.49 0 98.70
110 INT27591 Negative_regulation of Gene_expression of Alb 30 0.58 17.03 5.99 98.66
111 INT4422 Positive_regulation of Gene_expression of Alb 30 0.50 18.56 6.12 98.66
112 INT66491 Regulation of CES2 2 0.45 1.51 0.86 98.64
113 INT9210 Regulation of IL6 166 0.62 125.61 49.95 98.64
114 INT316980 Binding of PEAK1 2 0.01 0.5 0.04 98.48
115 INT117348 Regulation of EGFR 75 0.61 47.73 3.09 98.46
116 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 98.46
117 INT103096 Regulation of PPARA 113 0.60 62.47 14.57 98.44
118 INT49439 Gene_expression of Cpox 508 0.73 326.97 130.17 98.40
119 INT156612 Regulation of Gene_expression of FN1 7 0.43 4.44 0.79 98.40
120 INT145375 Transcription of CCND1 7 0.52 3.86 0.07 98.36
121 INT233847 Gene_expression of Zeb1 1 0.32 0.63 0.04 98.36
122 INT233840 Positive_regulation of Gene_expression of Zeb1 1 0.25 0.63 0.04 98.36
123 INT182311 Positive_regulation of Birc5 26 0.67 25.32 4.08 98.36
124 INT175416 Regulation of Negative_regulation of EGFR 4 0.60 3.94 0.14 98.32
125 INT188074 Gene_expression of GADD45A 12 0.65 5.11 0.28 98.32
126 INT279191 Regulation of Negative_regulation of Egfr 2 0.45 1.44 0.05 98.28
127 INT233846 Positive_regulation of Gene_expression of Ptpmt1 1 0.02 0.67 0.04 98.28
128 INT8103 Binding of TP53 46 0.44 40.2 2.96 98.26
129 INT122041 Binding of Ppara 308 0.48 189.17 51.48 98.24
130 INT60585 Regulation of TP53 59 0.59 54.55 5.21 98.24
131 INT105336 Regulation of AKT1 52 0.56 32.53 4.89 98.24
132 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 98.20
133 INT71779 Positive_regulation of Gene_expression of MAPK1 27 0.47 21.41 5.39 98.08
134 INT103240 Negative_regulation of Tyms 4 0.57 1.7 0.99 98.04
135 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64 98.04
136 INT110817 Negative_regulation of SCLC1 3 0.35 2.75 0.36 98.00
137 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 97.96
138 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 97.96
139 INT92383 Gene_expression of KRAS 38 0.65 32.94 1.32 97.90
140 INT233843 Gene_expression of Ptpmt1 1 0.02 0.67 0.04 97.88
141 INT1761 Positive_regulation of PTGER2 135 0.49 90.17 26.26 97.84
142 INT202225 Regulation of Fembrs1 3 0.10 1.3 0.57 97.82
143 INT202230 Regulation of UNC5B 4 0.04 2.3 0.49 97.82
144 INT202228 Regulation of Bdywt 1 0.04 1.3 0.48 97.82
145 INT202229 Regulation of GHRL 3 0.07 1.8 0.47 97.82
146 INT156501 Gene_expression of MAGEA1 8 0.18 10.26 0.08 97.80
147 INT49441 Negative_regulation of Cpox 494 0.59 303.22 177.46 97.80
148 INT103916 Negative_regulation of Phosphorylation of Egfr 12 0.59 7.03 0.47 97.80
149 INT153074 Negative_regulation of Phosphorylation of Erbb2 3 0.52 1.41 0.19 97.80
150 INT105960 Gene_expression of Cdh1 41 0.76 22.28 5.56 97.76
151 INT105959 Positive_regulation of Gene_expression of Cdh1 5 0.49 2.65 0.57 97.76
152 INT219482 Negative_regulation of WARS 7 0.35 6.92 0 97.76
153 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58 97.68
154 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 97.68
155 INT315821 Regulation of Transcription of RRM1 1 0.21 0.67 0.1 97.68
156 INT315817 Transcription of RRM1 2 0.42 0.67 0.09 97.68
157 INT73260 Regulation of Positive_regulation of PTGS1 3 0.26 2.65 1.37 97.60
158 INT11154 Binding of EGFR 149 0.48 96.23 6.29 97.56
159 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8 97.48
160 INT59891 Positive_regulation of GSTK1 46 0.67 17.66 5.33 97.48
161 INT135773 Negative_regulation of Gene_expression of HMOX1 31 0.53 28.31 3.32 97.48
162 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 97.36
163 INT286757 Gene_expression of Tusc2 1 0.77 44.57 1.56 97.36
164 INT263819 Regulation of Gene_expression of PTEN 1 0.25 0.63 0.32 97.32
165 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 97.28
166 INT101816 Localization of NFE2L2 17 0.77 6.91 1.69 97.20
167 INT119506 Negative_regulation of Egfr 32 0.55 23.75 3.67 97.20
168 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5 97.20
169 INT8556 Positive_regulation of NQO1 12 0.70 5.11 1.78 97.16
170 INT67039 Positive_regulation of Cpox 144 0.65 98.4 33.77 97.12
171 INT651 Positive_regulation of PTGS1 93 0.69 37.27 29.18 97.12
172 INT103914 Phosphorylation of Egfr 35 0.82 16.98 4.31 97.12
173 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 97.08
174 INT109594 Positive_regulation of ABL1 10 0.49 7.19 0.05 97.08
175 INT165179 Regulation of Positive_regulation of ABL1 1 0.15 0.95 0 97.08
176 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 97.04
177 INT55880 Negative_regulation of Gene_expression of CCL2 49 0.59 22.37 18.09 97.02
178 INT121369 Negative_regulation of Gene_expression of MIF 3 0.50 2.48 0.92 97.02
179 INT81929 Negative_regulation of Gene_expression of IL10 41 0.57 27.99 9.87 97.02
180 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57 97.00
181 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 96.96
182 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 96.96
183 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 96.84
184 INT2385 Gene_expression of MIF 57 0.68 40.74 12.78 96.84
185 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 96.84
186 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 96.80
187 INT125066 Negative_regulation of HDAC4 56 0.49 41.55 5.42 96.76
188 INT153075 Phosphorylation of Erbb2 5 0.73 2.06 0.19 96.76
189 INT178489 Negative_regulation of Kdr 31 0.42 25.65 0.66 96.72
190 INT177875 Positive_regulation of Positive_regulation of NFE2L2 18 0.66 9.4 0.4 96.68
191 INT37541 Gene_expression of SPP1 113 0.77 68.54 11.35 96.64
192 INT114093 Regulation of Cish 4 0.20 1.77 0.42 96.56
193 INT109316 Negative_regulation of Mapk8 72 0.59 50.59 17.24 96.56
194 INT36193 Negative_regulation of HTC2 4 0.38 3.11 0.65 96.56
195 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 96.52
196 INT244509 Regulation of Gene_expression of EIF2S2 1 0.27 1.14 0 96.52
197 INT234 Binding of Alb 151 0.48 52.34 32.97 96.44
198 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 96.40
199 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03 96.40
200 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41 96.36
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