D:Noninfiltrating Intraductal Carcinoma

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Disease Term
Synonyms Carcinoma Intraductal, Carcinoma Noninfiltrating Intraductal, CARCINOMAS INTRADUCTAL, Carcinomas Noninfiltrating Intraductal, Dcis, Ductal Carcinoma In Situ, Intraductal Carcinoma, Intraductal Carcinoma Noninfiltrating, Intraductal Carcinomas, Intraductal Carcinomas Noninfiltrating, Noninfiltrating Intraductal Carcinomas
Documents 114
Hot Single Events 111
Hot Interactions 9

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Noninfiltrating Intraductal Carcinoma. They are ordered first by their relevance to Noninfiltrating Intraductal Carcinoma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT172981 PAN3 Negative_regulation of SMAD4 1 0.01 0.98 0 95.92
2 INT225262 Egf Regulation of Gene_expression of S100a7a 1 0.04 3.31 0.06 93.28
3 INT343164 ACSL4 Regulation of Positive_regulation of ALOX15 1 0.01 1.08 0.03 87.80
4 INT245075 Binding of ESR1 and NR4A1 1 0.01 1.08 0.03 87.12
5 INT225261 S100a7a Positive_regulation of Egf 1 0.07 1.13 0.05 82.44
6 INT191095 Positive_regulation of Binding of Apc and Esr1 1 0.06 1.08 0 82.32
7 INT191096 Negative_regulation of Binding of Apc and Esr1 1 0.05 1.07 0 82.16
8 INT191098 Binding of Apc and Esr1 1 0.04 1.06 0 82.16
9 INT314687 ESR1 Regulation of PGR 1 0.27 0.88 0 81.04
10 INT225259 Egfr Regulation of Gene_expression of S100a7a 1 0.04 0.98 0.04 71.00
11 INT71904 Binding of ESR1 and PGR 6 0.34 3.79 0.27 66.92
12 INT233771 Binding of KRT7 and KRT20 1 0.01 1.72 0 60.20
13 INT233777 Binding of KRT20 and Cea 1 0.01 3.42 0 59.88
14 INT250667 KLF1 Regulation of ERBB2 1 0.00 1.16 0 54.84
15 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15 52.36
16 INT219875 Binding of KRT7 and Krt20 1 0.01 1.32 0.04 51.52
17 INT219857 Binding of Krt20 and Nbr1 1 0.00 1.31 0.04 51.32
18 INT191097 Neu1 Positive_regulation of Shc1 1 0.04 1.96 0 51.00
19 INT191099 Erbb2 Positive_regulation of Shc1 1 0.08 1.95 0 51.00
20 INT266388 S100a6 Negative_regulation of Mapk8 1 0.03 0.49 0.06 48.00
21 INT266417 Binding of TGM2 and S100a11 1 0.01 0.86 0.16 47.84
22 INT234179 Binding of DDR1 and ESR1 1 0.05 0.86 0 43.68
23 INT266384 Binding of Ager and S100a6 1 0.01 1.32 0.11 33.60
24 INT266389 Binding of C2 and S100a6 1 0.04 0.5 0.07 32.40
25 INT314684 Binding of CCND1 and ESR1 1 0.22 0.42 0 29.84
26 INT266390 Binding of S100a6 and Trp53 1 0.04 0.51 0.07 28.88
27 INT225263 S100a7a Regulation of Phosphorylation of Egf 1 0.04 0.84 0 25.76
28 INT173058 INCENP Positive_regulation of Gene_expression of VEGFA 1 0.03 1.48 0.08 21.48
29 INT343157 ACSL4 Regulation of Gene_expression of ALOX15 1 0.01 0.67 0.07 20.48
30 INT173057 Positive_regulation of HIF1A Positive_regulation of Gene_expression of VEGFA 1 0.24 1.49 0.08 19.80
31 INT266394 Binding of S100a4 and Trp53 1 0.03 0.59 0.08 11.28
32 INT173060 Negative_regulation of VHLL Positive_regulation of Positive_regulation of HIF1A 1 0.04 0.66 0.04 10.64
33 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 5.00
34 INT266391 Binding of Ager and S100a1 1 0.01 5.63 1.69 5.00
35 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57 5.00
36 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 5.00
37 INT172982 Binding of MUC1 and MUC4 1 0.30 2.46 0.78 5.00
38 INT266408 Binding of HMGB1 and Ager 1 0.01 2.57 0.76 5.00
39 INT181084 Binding of S100a8 and S100a9 6 0.42 2.91 0.62 5.00
40 INT266381 Positive_regulation of Ager Positive_regulation of Nfkb1 1 0.00 0.77 0.55 5.00
41 INT266376 Binding of Ager and Itgam 1 0.00 2.31 0.54 5.00
42 INT266393 Binding of Ager and Fn1 1 0.00 0.82 0.39 5.00
43 INT266382 Binding of Col4a1 and Fn1 1 0.00 0.82 0.39 5.00
44 INT266397 Binding of Ager and Col4a1 1 0.00 0.81 0.38 5.00
45 INT266419 HMGB1 Positive_regulation of Ager 1 0.01 1.37 0.37 5.00
46 INT266402 Binding of S100P and Ager 1 0.00 2.25 0.35 5.00
47 INT266383 Binding of Ager and S100b 1 0.01 3.48 0.33 5.00
48 INT266375 S100b Positive_regulation of Ager 1 0.02 1.8 0.31 5.00
49 INT222301 Binding of ERBB2 and ESR1 5 0.36 5.07 0.29 5.00
50 INT245072 PPARA Regulation of Gene_expression of CXCR4 1 0.07 0.68 0.26 5.00
51 INT266421 Binding of HMGB1 and Il1 1 0.02 0.37 0.24 5.00
52 INT266418 Binding of HMGB1 and Tlr4 1 0.09 0.37 0.23 5.00
53 INT238802 Binding of Ager and Renbp 6 0.02 6.46 0.22 5.00
54 INT266405 S100b Positive_regulation of Gene_expression of TFAM 1 0.00 1.02 0.21 5.00
55 INT266380 Binding of Tlr2 and Il1 1 0.01 0.76 0.21 5.00
56 INT266401 S100b Positive_regulation of S100b Positive_regulation of Ager 1 0.01 0.96 0.21 5.00
57 INT266423 Binding of HMGB1 and Mapk3 1 0.04 0.9 0.2 5.00
58 INT266410 Binding of HMGB1 and Mapk14 1 0.03 0.91 0.2 5.00
59 INT266416 Binding of HMGB1 and Mapk1 1 0.06 0.9 0.2 5.00
60 INT266414 Binding of HMGB1 and Mapk8 1 0.03 0.91 0.2 5.00
61 INT266404 Binding of HMGB1 and Thbd 1 0.06 0.3 0.2 5.00
62 INT266422 HMGB1 Positive_regulation of Binding of Ager 1 0.01 0.92 0.16 5.00
63 INT266412 Binding of S100A12 and Ager 1 0.01 1.03 0.15 5.00
64 INT181752 Binding of CPOX and ESR1 1 0.02 0.89 0.14 5.00
65 INT266413 Positive_regulation of Binding of HMGB1 and Col4a1 1 0.02 1.05 0.14 5.00
66 INT266411 Binding of HMGB1 and Col4a1 1 0.01 1.05 0.14 5.00
67 INT266403 Negative_regulation of Binding of S100P and Ager 1 0.00 0.74 0.13 5.00
68 INT184527 Binding of DUS2L and HEPACAM 1 0.00 0.86 0.13 5.00
69 INT175401 Binding of EGFR and VEGFA 2 0.13 1.49 0.13 5.00
70 INT266386 Binding of S100a1 and Trp53 1 0.03 0.64 0.1 5.00
71 INT266385 S100a6 Positive_regulation of Ager 1 0.01 0.84 0.1 5.00
72 INT266373 Itgam Positive_regulation of Ager 1 0.01 0.84 0.1 5.00
73 INT266396 Binding of Ager and S100a4 1 0.01 0.59 0.1 5.00
74 INT173061 Binding of HIF1A and LILRA3 1 0.03 1.24 0.09 5.00
75 INT220394 MRXS5 Positive_regulation of Gene_expression of CYP19A1 1 0.00 0.89 0.09 5.00
76 INT173062 Binding of HIF1A and VHLL 1 0.04 1.26 0.09 5.00
77 INT232559 Map3k1 Positive_regulation of Esr1 1 0.19 0.26 0.09 5.00
78 INT232557 Erbb2 Positive_regulation of Esr1 1 0.23 0.26 0.09 5.00
79 INT220412 Cpox Positive_regulation of Gene_expression of CYP19A1 1 0.01 0.9 0.09 5.00
80 INT250661 Binding of EGF and ERBB2 2 0.11 0.82 0.08 5.00
81 INT277835 EPO Positive_regulation of Localization of VEGFA 1 0.03 1.36 0.08 5.00
82 INT185279 Binding of CCND1 and CDK4 4 0.13 2.05 0.08 5.00
83 INT173106 VEGFA Positive_regulation of Fos 1 0.44 0.64 0.08 5.00
84 INT185278 Binding of CCND1 and CDK6 3 0.13 1.62 0.08 5.00
85 INT250662 FNTA Positive_regulation of Positive_regulation of RASGRP1 1 0.00 0.79 0.07 5.00
86 INT268679 Binding of HDAC1 and NCOR2 3 0.17 2.8 0.07 5.00
87 INT268673 Binding of NCOR2 and BCOR 1 0.01 2.54 0.07 5.00
88 INT268675 Binding of NCOR2 and SIN3A 1 0.27 2.54 0.07 5.00
89 INT266398 Binding of S100b and Trp53 1 0.06 0.92 0.07 5.00
90 INT268678 Binding of HDAC2 and NCOR2 1 0.18 2.67 0.07 5.00
91 INT266374 Binding of S100a1 and S100a9 1 0.09 0.17 0.05 5.00
92 INT268677 IFNA2 Positive_regulation of XRCC1 1 0.05 0.75 0.05 5.00
93 INT266387 Binding of S100a1 and S100a8 1 0.09 0.17 0.05 5.00
94 INT173052 Binding of LILRA3 and VHLL 1 0.01 0.62 0.05 5.00
95 INT268674 IL2 Positive_regulation of XRCC1 1 0.08 0.75 0.05 5.00
96 INT173053 Binding of VEGFA and NRP2 3 0.12 1.36 0.04 5.00
97 INT268676 Binding of HDAC1 and BCOR 1 0.01 1.31 0.04 5.00
98 INT335212 RDH5 Positive_regulation of NFAT5 1 0.00 0.96 0.04 5.00
99 INT173056 Binding of NRP2 and NRP1 2 0.24 0.61 0.04 5.00
100 INT251892 Binding of Plau and Naf1 1 0.07 0.06 0.04 5.00
101 INT266379 S100a8 Positive_regulation of Ager 1 0.01 0.3 0.04 5.00
102 INT173051 Binding of VEGFA and NRP1 16 0.44 1.29 0.04 5.00
103 INT266372 Binding of S100a1 and S100a4 1 0.11 0.15 0.04 5.00
104 INT213903 Binding of EGFR and ERBB2 10 0.37 5.03 0.04 5.00
105 INT335213 RDH5 Positive_regulation of CREM 1 0.00 0.96 0.04 5.00
106 INT266392 S100a9 Positive_regulation of Ager 1 0.01 0.3 0.04 5.00
107 INT245076 CXCR4 Regulation of Gene_expression of VEGFA 1 0.16 1.05 0.03 5.00
108 INT173055 Binding of VEGFA and NCOR2 1 0.02 0.34 0.03 5.00
109 INT314686 TP53 Regulation of Gene_expression of MDM2 1 0.21 0.96 0.03 5.00
110 INT314677 TP53 Regulation of Positive_regulation of CDKN2A 1 0.27 0.97 0.03 5.00
111 INT266415 Binding of ROS1 and S100a6 1 0.02 0.82 0.03 5.00
112 INT314690 TP53 Regulation of Gene_expression of ZBTB7A 1 0.33 0.97 0.03 5.00
113 INT250665 EGFR Positive_regulation of PIK3CB 1 0.21 1.39 0 5.00
114 INT335214 Binding of ESR1 and RARS 1 0.08 0.92 0 5.00
115 INT289608 Binding of CDK2 and CCNE2 5 0.06 4.89 0 5.00
116 INT225265 Gene_expression of S100a7a Positive_regulation of VEGFA 1 0.01 0.23 0 5.00
117 INT245071 Binding of CXCL12 and KDELR1 1 0.04 1.49 0 5.00
118 INT121650 Negative_regulation of Binding of CXCL12 and CXCR4 2 0.47 1.61 0 5.00
119 INT314746 Akt1 Positive_regulation of Phosphorylation of MDM2 1 0.32 1.16 0 5.00
120 INT314741 Binding of VEGFA and Akt1 1 0.36 0.66 0 5.00
121 INT266925 Regulation of Binding of EGFR and ERBB2 1 0.26 0.5 0 5.00
122 INT250656 ELK1 Positive_regulation of Gene_expression of VEGFA 1 0.07 0.74 0 5.00
123 INT225258 Egf Positive_regulation of Gene_expression of S100a7a 1 0.07 1.7 0 5.00
124 INT250659 Negative_regulation of PTEN Positive_regulation of Positive_regulation of PIK3CB 1 0.02 1.18 0 5.00
125 INT245078 FGF2 Positive_regulation of CXCR4 1 0.07 1.36 0 5.00
126 INT314692 Binding of TBX2 and TBX3 1 0.27 0.84 0 5.00
127 INT245073 VEGFA Positive_regulation of CXCR4 1 0.27 5.09 0 5.00
128 INT314742 Binding of RAD51 and Brca2 1 0.06 1.05 0 5.00
129 INT245074 Gene_expression of VHL Negative_regulation of Gene_expression of CXCR4 1 0.31 1.84 0 5.00
130 INT234182 Binding of BRCA2 and PALB2 1 0.41 1.43 0 5.00
131 INT314693 Binding of TBX2 and TBX5 1 0.16 0.84 0 5.00
132 INT234180 Binding of BRCA1 and BRIP1 1 0.33 1.37 0 5.00
133 INT250668 AKT1 Positive_regulation of MTOR 1 0.16 1.26 0 5.00
134 INT245077 Binding of ESR1 and CXCL12 1 0.06 1.42 0 5.00
135 INT314743 Binding of RAD51 and Brca1 1 0.06 1.06 0 5.00
136 INT335215 RDH5 Positive_regulation of Negative_regulation of ERBB3 1 0.03 0.98 0 5.00
137 INT314740 Binding of ESR1 and Brca1 1 0.16 0.69 0 5.00
138 INT314682 Binding of TBX2 and TBX4 1 0.16 0.84 0 5.00
139 INT173054 NRP1 Positive_regulation of KDR 1 0.08 0.34 0 5.00
140 INT250658 FOS Positive_regulation of CCND1 1 0.03 0.6 0 5.00
141 INT250663 Phosphorylation of AKT1 Positive_regulation of MTOR 1 0.16 1.26 0 5.00
142 INT220411 Ptger2 Positive_regulation of Cyp19a1 1 0.09 0.83 0 5.00
143 INT266407 Binding of ALB and Ager 1 0.00 1.42 0 5.00
144 INT343158 ACSL4 Regulation of Regulation of ALOX15 1 0.01 0.47 0 5.00
145 INT234178 Binding of BRCA1 and BRCA2 2 0.40 1.52 0 5.00
146 INT250666 ERBB2 Positive_regulation of PIK3CB 1 0.15 0.69 0 5.00
147 INT343163 ACSL4 Regulation of Gene_expression of PTGS2 1 0.08 0.5 0 5.00
148 INT225266 Erbb2 Positive_regulation of Gene_expression of VEGFA 1 0.04 0.79 0 5.00
149 INT250718 PIK3CB Regulation of Gene_expression of Birc5 1 0.23 0.91 0 5.00
150 INT314683 NUDT6 Positive_regulation of FGF1 1 0.02 1.17 0 5.00
151 INT314744 Binding of KDR and Akt1 1 0.13 0.66 0 5.00
152 INT225260 S100a7a Positive_regulation of Phosphorylation of Egfr 1 0.07 0.18 0 5.00
153 INT251893 Serpine1 Negative_regulation of Plau 1 0.39 0.6 0 5.00
154 INT220410 Ptger2 Positive_regulation of Rtcd1 1 0.00 0.83 0 5.00
155 INT250657 STAT3 Positive_regulation of Gene_expression of VEGFA 1 0.07 0.74 0 5.00
156 INT225267 Gene_expression of S100a7a Positive_regulation of Gene_expression of VEGFA 1 0.01 0.23 0 5.00
157 INT266395 Renbp Positive_regulation of Ager 1 0.00 0.31 0 5.00
158 INT314688 Binding of CCNE1 and CDK2 1 0.04 1.41 0 5.00
159 INT343155 ACSL4 Regulation of CPOX 1 0.01 1.03 0 5.00
160 INT343162 ACSL4 Regulation of LOX 1 0.03 1.04 0 5.00
161 INT314678 Binding of CCNE1 and CCNE2 1 0.03 1.41 0 5.00
162 INT182924 Binding of RARA and NR1H4 3 0.02 1.9 0 5.00
163 INT335216 RARS Negative_regulation of Binding of ESR1 1 0.10 0.92 0 5.00
164 INT343161 ACSL4 Regulation of Gene_expression of TSPO 1 0.25 0.75 0 5.00
165 INT225268 Negative_regulation of S100a7a Negative_regulation of Gene_expression of VEGFA 1 0.01 0.24 0 5.00
166 INT251891 Serpine1 Negative_regulation of Plg 1 0.12 3.13 0 5.00
167 INT266409 Binding of ALB and Renbp 1 0.00 1.41 0 5.00
168 INT232558 Binding of Erbb2 and Esr1 1 0.24 0.59 0 5.00
169 INT314745 Binding of TP53 and Brca1 1 0.18 1.17 0 5.00
170 INT277836 EGFR Positive_regulation of VEGFA 1 0.24 0.47 0 5.00
171 INT314689 Binding of KITLG and UBR1 1 0.00 0.71 0 5.00
172 INT343159 ACSL4 Regulation of Gene_expression of LOX 1 0.07 1.04 0 5.00
173 INT314691 ERBB2 Negative_regulation of TP53 1 0.28 1.23 0 5.00
174 INT187640 Binding of EGFR and KLF1 3 0.01 2.54 0 5.00
175 INT250664 PIK3CB Positive_regulation of AKT1 1 0.09 0.62 0 5.00
176 INT250660 PIK3CB Negative_regulation of AKT1 1 0.09 0.83 0 5.00
177 INT173050 Binding of VEGFA and NRP1 Positive_regulation of KDR 1 0.08 0.35 0 5.00
178 INT314685 TBX2 Negative_regulation of CDKN2A 1 0.32 1.16 0 5.00
179 INT343156 Binding of TSPO and DBI 1 0.04 0.63 0 5.00
180 INT314680 Positive_regulation of TBX2 Negative_regulation of CDKN2A 1 0.34 1.16 0 5.00
181 INT314679 NEU1 Negative_regulation of TP53 1 0.12 1.23 0 5.00
182 INT250669 Binding of TP53 and ST8SIA4 1 0.02 0.51 0 5.00
183 INT335218 RARS Negative_regulation of Binding of ESR1 and RARS 1 0.04 0.92 0 5.00
184 INT266420 Binding of S100P and S100z 1 0.04 0.05 0 5.00
185 INT343160 ACSL4 Regulation of Positive_regulation of ALOX5 1 0.02 0.32 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Noninfiltrating Intraductal Carcinoma. They are ordered first by their pain relevance and then by number of times they were reported in Noninfiltrating Intraductal Carcinoma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT144430 Gene_expression of Erbb2 137 0.77 103.87 8.66 99.84
2 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 99.76
3 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 99.76
4 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49 99.76
5 INT6210 Binding of Nppa 39 0.47 14.35 7.21 99.76
6 INT15687 Regulation of ESR1 91 0.60 40.42 7.95 99.72
7 INT52962 Binding of ERBB2 77 0.47 50.03 1.49 99.66
8 INT1995 Gene_expression of ptd 2 0.58 1.98 0.16 99.62
9 INT84367 Gene_expression of S100a7a 2 0.15 25.36 1.16 99.48
10 INT21788 Positive_regulation of ERBB2 49 0.66 28.88 1.68 99.48
11 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 99.48
12 INT266927 Positive_regulation of Transcription of ERBB2 2 0.46 2.5 0.03 99.48
13 INT250698 Positive_regulation of Transcription of TP53 3 0.18 3.68 0 99.48
14 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39 99.44
15 INT53082 Positive_regulation of Gene_expression of Ptgs2 47 0.64 25.39 11.39 99.44
16 INT55952 Transcription of TP53 16 0.61 12.14 2.36 99.32
17 INT24328 Gene_expression of Egf 97 0.75 59.65 9.42 99.24
18 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.24
19 INT171372 Positive_regulation of Gene_expression of Egf 16 0.66 9.82 0.84 99.24
20 INT181787 Transcription of ERBB2 13 0.71 10.03 0.16 99.22
21 INT114246 Positive_regulation of Negative_regulation of EGFR 13 0.49 8.67 0.7 99.08
22 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55 99.08
23 INT144428 Positive_regulation of Gene_expression of Erbb2 41 0.69 41.4 4.13 98.96
24 INT78199 Gene_expression of Neu1 65 0.75 62.88 7.16 98.96
25 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 98.90
26 INT78990 Regulation of Cpox 72 0.57 35.22 18.16 98.82
27 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 98.80
28 INT71906 Regulation of Gene_expression of ESR1 22 0.41 11.01 0.98 98.80
29 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 98.64
30 INT131286 Binding of Egfr 26 0.44 13.58 0.78 98.56
31 INT173223 Negative_regulation of BRCA2 7 0.54 6.79 0.25 98.52
32 INT119062 Negative_regulation of BRCA1 12 0.49 13.7 1.36 98.52
33 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 98.48
34 INT125066 Negative_regulation of HDAC4 56 0.49 41.55 5.42 98.48
35 INT88318 Gene_expression of CXCR4 208 0.77 189.67 31.72 98.28
36 INT237247 Regulation of Mri1 6 0.27 4.64 1.2 98.20
37 INT78524 Positive_regulation of Neu1 6 0.67 8.9 4.4 98.20
38 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23 97.92
39 INT113705 Gene_expression of Egfr 228 0.78 149.05 7.59 97.92
40 INT120563 Positive_regulation of Gene_expression of Egfr 56 0.70 46.19 1.82 97.92
41 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 97.86
42 INT186115 Negative_regulation of Negative_regulation of EGFR 5 0.57 3.42 0.33 97.80
43 INT266362 Binding of S100A7 1 0.14 1.55 0.04 97.68
44 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 97.48
45 INT171683 Negative_regulation of Negative_regulation of TXK 3 0.06 1.28 0.46 97.48
46 INT318128 Binding of Cdo1 1 0.35 0.91 0 97.36
47 INT197765 Gene_expression of Sln 26 0.58 12.11 0.45 97.32
48 INT162109 Negative_regulation of Gene_expression of Esr1 4 0.16 2.41 0.12 97.20
49 INT266330 Positive_regulation of S100a1 4 0.44 2.98 0.39 96.96
50 INT180578 Regulation of HEYL 3 0.06 3.15 0.49 96.72
51 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15 96.68
52 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46 96.52
53 INT67656 Positive_regulation of Positive_regulation of PTGS2 12 0.46 4.83 6.17 96.52
54 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71 96.32
55 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 96.16
56 INT71019 Negative_regulation of SMAD4 12 0.42 6.88 0.43 95.92
57 INT173000 Negative_regulation of Localization of SMAD4 1 0.22 0.98 0 95.92
58 INT173008 Localization of SMAD4 1 0.38 0.97 0 95.60
59 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 95.52
60 INT46124 Binding of Mga 2 0.31 3.13 0.39 95.52
61 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 95.28
62 INT17237 Regulation of Esr1 74 0.43 49.09 17.25 95.20
63 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 94.68
64 INT93886 Positive_regulation of Gene_expression of PGR 19 0.52 15.78 1.89 94.68
65 INT173011 Localization of PAN3 1 0.01 0.91 0 94.56
66 INT88947 Positive_regulation of Gene_expression of Pgr 22 0.64 7 4.39 94.32
67 INT318125 Gene_expression of Cdo1 1 0.72 3.53 0 94.00
68 INT318124 Negative_regulation of Gene_expression of Cdo1 1 0.54 0.95 0 94.00
69 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19 93.80
70 INT193815 Regulation of Gene_expression of CXCR4 17 0.61 20.27 1.15 93.48
71 INT5622 Gene_expression of Nppa 101 0.78 49.46 25.31 93.20
72 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 92.76
73 INT651 Positive_regulation of PTGS1 93 0.69 37.27 29.18 92.60
74 INT266354 Gene_expression of S100A7 9 0.58 7.35 0.75 92.56
75 INT266351 Localization of S100A7 1 0.28 0.84 0.03 92.56
76 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 92.00
77 INT88718 Negative_regulation of Erbb2 11 0.58 12.98 0.84 91.96
78 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 91.68
79 INT225249 Negative_regulation of Phosphorylation of Src 1 0.16 1.51 0 91.28
80 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47 91.08
81 INT137350 Phosphorylation of Src 13 0.45 4.14 3.32 90.88
82 INT225241 Positive_regulation of Gene_expression of S100a7a 1 0.09 4.54 0.12 90.12
83 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52 89.32
84 INT86370 Regulation of CDH1 10 0.54 13.89 0.7 88.60
85 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 88.32
86 INT174486 Regulation of Gene_expression of CD4 12 0.36 6.09 1.39 88.32
87 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 88.20
88 INT28528 Gene_expression of MSMB 25 0.65 7.66 3.49 87.92
89 INT89774 Gene_expression of NR4A1 13 0.77 9.47 1.02 87.72
90 INT266361 Regulation of S100A7 1 0.18 1.52 0 86.96
91 INT159190 Gene_expression of KRT5 31 0.65 26.67 0.56 86.92
92 INT180588 Gene_expression of HEYL 13 0.52 8.37 1.19 86.84
93 INT172996 Gene_expression of MUC2 14 0.69 11.01 0.42 86.52
94 INT24042 Gene_expression of MUC5AC 98 0.77 74.99 6.18 86.52
95 INT100059 Gene_expression of MUC4 30 0.75 31.58 4.95 86.52
96 INT223599 Regulation of MTOR 14 0.42 8.52 0.49 86.32
97 INT93079 Positive_regulation of ALOX15 8 0.70 12.46 6.22 85.76
98 INT188317 Positive_regulation of Gene_expression of PDGFA 15 0.46 12.7 0.91 85.72
99 INT101859 Gene_expression of MCF2 34 0.49 19.45 1.51 85.52
100 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9 85.52
101 INT184528 Negative_regulation of DUS2L 1 0.01 1.67 0.16 85.16
102 INT21632 Positive_regulation of Adh1 32 0.70 15.67 11.65 83.28
103 INT237250 Regulation of Gene_expression of Fus 1 0.34 1.45 0.11 83.08
104 INT231240 Gene_expression of Fus 2 0.56 20.05 3.9 82.68
105 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 82.48
106 INT266369 Gene_expression of S100A7A 1 0.29 4.27 0.26 82.04
107 INT10836 Negative_regulation of IL8 95 0.59 52.59 24.71 81.84
108 INT79270 Gene_expression of MKI67 113 0.77 63.52 3.38 81.68
109 INT181756 Positive_regulation of Erbb2 6 0.46 4.12 0.28 81.60
110 INT22708 Gene_expression of MUC1 297 0.78 232.71 24.19 80.88
111 INT84809 Positive_regulation of Gene_expression of MUC1 39 0.70 36.42 3.75 80.88
112 INT245083 Regulation of Positive_regulation of CXCL12 1 0.39 1.6 0 79.96
113 INT123528 Negative_regulation of Gene_expression of Vegfa 10 0.57 7.08 2.31 79.92
114 INT173002 Negative_regulation of MUC2 1 0.38 0.81 0 79.64
115 INT48324 Positive_regulation of ODZ1 2 0.45 3.93 0.1 79.60
116 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89 79.52
117 INT121659 Positive_regulation of CXCL12 8 0.53 9.17 2.36 79.44
118 INT119271 Positive_regulation of BCS1L 13 0.50 7.56 0.39 78.12
119 INT163545 Gene_expression of PDGFRB 39 0.78 25.5 2.2 77.68
120 INT108202 Positive_regulation of PIK3CG 47 0.67 25.83 8.25 76.56
121 INT183673 Positive_regulation of Localization of PASK 2 0.43 2.4 0 76.00
122 INT49441 Negative_regulation of Cpox 494 0.59 303.22 177.46 75.96
123 INT78005 Negative_regulation of Binding of Cpox 7 0.31 3.19 1.7 75.96
124 INT50290 Binding of Cpox 29 0.27 17.19 8.01 75.52
125 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 75.40
126 INT266365 Regulation of Binding of S100A7 1 0.11 0.78 0.04 75.24
127 INT225254 Phosphorylation of S100a7a 1 0.12 1.04 0.05 75.12
128 INT48792 Regulation of ERBB2 48 0.57 36.56 1.8 74.92
129 INT103914 Phosphorylation of Egfr 35 0.82 16.98 4.31 74.44
130 INT299480 Transcription of LOX 3 0.13 2.87 0.14 73.76
131 INT59433 Gene_expression of PASK 24 0.68 25.13 3.21 72.56
132 INT102249 Binding of HIF1A 39 0.36 30.47 1.04 72.40
133 INT232550 Negative_regulation of Gene_expression of Erbb2 9 0.43 4.96 0.07 72.36
134 INT232554 Negative_regulation of Transcription of Erbb2 1 0.42 1.16 0 72.36
135 INT232555 Negative_regulation of Gene_expression of Sh3pxd2a 1 0.08 1.22 0 72.36
136 INT232552 Negative_regulation of Sh3pxd2a 1 0.08 1.22 0 72.36
137 INT23010 Positive_regulation of CYP19A1 28 0.58 24.18 5.37 71.84
138 INT96771 Localization of PASK 3 0.80 11.6 0.51 71.84
139 INT202196 Transcription of Erbb2 3 0.69 3.87 0.51 71.68
140 INT157135 Positive_regulation of MKI67 10 0.60 7.51 0.28 71.56
141 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 71.44
142 INT176571 Negative_regulation of Positive_regulation of ESR1 5 0.47 3.15 0.17 70.84
143 INT113111 Regulation of CXCR4 14 0.61 12.81 1.39 70.72
144 INT232551 Gene_expression of Sh3pxd2a 1 0.14 1.32 0 70.24
145 INT111477 Gene_expression of KRT7 90 0.74 86.76 4.07 69.60
146 INT85084 Gene_expression of KRT19 66 0.73 42.56 1.82 69.40
147 INT232510 Negative_regulation of Gene_expression of CXCR4 18 0.58 20.27 2.54 69.20
148 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 69.16
149 INT21032 Gene_expression of Adh1 23 0.78 22.1 6.14 68.64
150 INT103674 Positive_regulation of Gene_expression of CXCR4 32 0.69 37.1 3.08 68.08
151 INT118292 Negative_regulation of Phosphorylation of EGFR 27 0.59 13.62 1.54 67.80
152 INT213917 Negative_regulation of Phosphorylation of ERBB2 9 0.54 8.68 0.91 67.80
153 INT250717 Negative_regulation of Phosphorylation of MKI67 1 0.03 1.33 0 67.80
154 INT100664 Negative_regulation of MKI67 12 0.10 9.77 0 67.80
155 INT37296 Binding of Esr1 117 0.43 62.51 27.33 67.76
156 INT225246 Phosphorylation of Ptpn11 1 0.28 0.9 0 67.76
157 INT95652 Gene_expression of Krt20 54 0.61 53.69 3.31 67.68
158 INT1261 Localization of Adh1 63 0.81 19.36 16.09 67.68
159 INT93168 Gene_expression of Ttf1 24 0.63 17.18 1.14 67.68
160 INT86889 Gene_expression of Cdx2 8 0.60 4.23 1.02 67.68
161 INT127655 Localization of MKI67 6 0.73 3.72 0.26 67.08
162 INT201870 Phosphorylation of MKI67 2 0.06 1.4 0 66.32
163 INT210 Positive_regulation of Sln 10 0.43 4.06 0.49 66.12
164 INT96994 Phosphorylation of EGFR 99 0.82 52.75 7.33 65.84
165 INT176588 Phosphorylation of ERBB2 27 0.78 16.37 0.81 65.84
166 INT100061 Binding of MUC2 1 0.33 1 0 65.84
167 INT298024 Positive_regulation of Gene_expression of Sln 2 0.26 1.44 0 65.68
168 INT266346 Gene_expression of S100a11 1 0.23 0.74 0.05 65.40
169 INT266336 Positive_regulation of Gene_expression of S100a11 1 0.18 0.74 0.05 65.40
170 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18 64.80
171 INT237245 Positive_regulation of Gene_expression of Fus 1 0.38 4.8 1.55 64.72
172 INT191252 Localization of DDR1 4 0.45 3.15 0.04 64.48
173 INT343192 Gene_expression of ACSL4 1 0.75 20.21 0.35 64.44
174 INT343200 Binding of ACSL4 1 0.36 3.32 0.23 64.44
175 INT90673 Gene_expression of LOX 66 0.65 69.71 12.18 64.16
176 INT343179 Binding of LOX 1 0.09 2.51 0.14 64.16
177 INT80174 Positive_regulation of Gene_expression of Neu1 23 0.37 17.82 1.12 63.88
178 INT89676 Gene_expression of BID 8 0.31 8.98 0.1 63.52
179 INT34830 Regulation of PGR 14 0.45 6.99 2.32 63.04
180 INT105948 Gene_expression of AURKA 5 0.65 4.26 0.03 63.00
181 INT105949 Positive_regulation of Gene_expression of AURKA 3 0.49 1.91 0.03 63.00
182 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54 62.80
183 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61 62.24
184 INT1762 Negative_regulation of PTGER2 64 0.43 28.21 11.27 62.04
185 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 60.00
186 INT180580 Binding of HEYL 7 0.17 4.49 1.15 60.00
187 INT92592 Transcription of PTGER2 6 0.32 4.52 0.47 60.00
188 INT105782 Positive_regulation of Krt20 9 0.20 9.62 0.53 59.84
189 INT35486 Regulation of PTGER2 39 0.36 19.03 6.75 59.64
190 INT266931 Positive_regulation of Binding of EGFR 6 0.50 5.44 0 59.40
191 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91 59.40
192 INT11154 Binding of EGFR 149 0.48 96.23 6.29 59.04
193 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66 58.88
194 INT105390 Positive_regulation of Gene_expression of HIF1A 27 0.49 26.3 2.88 58.88
195 INT22455 Binding of Nbr1 8 0.21 10.57 0.93 58.56
196 INT131931 Binding of KRT7 13 0.36 19.24 0.5 58.56
197 INT165455 Negative_regulation of NAF1 2 0.24 1.26 0.26 58.48
198 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 58.16
199 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 57.40
200 INT227015 Gene_expression of S100A14 2 0.39 2.01 0.12 56.32
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