D:Nutritional Deficiencies

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Disease Term
Synonyms Malnutrition, Nutritional Deficiency, Nutritional Disorder, Nutritional Disorders, Undernutrition
Documents 341
Hot Single Events 88
Hot Interactions 3

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Nutritional Deficiencies. They are ordered first by their relevance to Nutritional Deficiencies and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT207551 IGF1 Positive_regulation of Gene_expression of GH1 2 0.22 1.18 0.11 99.04
2 INT73076 IGF1 Positive_regulation of GH1 4 0.45 0.99 0.15 99.04
3 INT241853 Binding of SLC40A1 and HAMP 3 0.41 5.35 0.43 87.28
4 INT222438 Nps Positive_regulation of Localization of Pomc 1 0.01 0.66 0 74.36
5 INT222413 Nps Positive_regulation of Localization of Crh 1 0.03 0.66 0 74.36
6 INT326625 Binding of ALB and Trf 1 0.01 0.64 0.04 63.36
7 INT153116 Binding of SPINK1 and Abpa 1 0.01 1.32 0.4 63.04
8 INT153114 Binding of Abpa and Ctrc 1 0.00 1.22 0.4 62.60
9 INT266103 Binding of COMT and SNRNP70 1 0.04 0.78 0.21 60.48
10 INT296372 Binding of IDUA and ACD 1 0.03 2.72 0.23 55.04
11 INT303399 Binding of Jag1 and Myh3 1 0.50 0.85 0 54.64
12 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91 42.32
13 INT188805 TNF Positive_regulation of Gene_expression of Crp 1 0.15 2.96 0.95 42.32
14 INT188803 Il1 Positive_regulation of Gene_expression of Crp 1 0.03 2.95 0.94 42.32
15 INT303388 Binding of Laptm5 and Rnf123 1 0.00 0.18 0 16.32
16 INT2161 Gnrh1 Positive_regulation of Localization of LH 33 0.73 0.87 14.34 5.00
17 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 0.64 2.12 14.2 5.00
18 INT2714 Pomc Positive_regulation of Localization of Prl 17 0.79 0.5 8.18 5.00
19 INT20133 Trh Positive_regulation of Localization of Prl 23 0.78 2.04 5.44 5.00
20 INT1392 Trh Regulation of Prl 15 0.29 2.47 4.29 5.00
21 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11 5.00
22 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79 5.00
23 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
24 INT9786 Gnrh1 Regulation of LH 7 0.40 0.58 1.82 5.00
25 INT317184 BMS1 Regulation of Gene_expression of NAV1 1 0.03 1.94 1.62 5.00
26 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25 5.00
27 INT62368 Gal Positive_regulation of Localization of LH 3 0.36 0 1.2 5.00
28 INT222516 Binding of Calcrl and Ramp1 5 0.17 0.11 1.12 5.00
29 INT36186 Npy Positive_regulation of Localization of Gnrh1 4 0.75 0.09 0.96 5.00
30 INT206857 Binding of Calca and Calcrl 4 0.37 1.9 0.95 5.00
31 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92 5.00
32 INT78062 Il1a Positive_regulation of Localization of Il6 3 0.24 0.48 0.9 5.00
33 INT266102 Binding of PITX2 and RS1 1 0.00 0.64 0.8 5.00
34 INT222528 Abat Positive_regulation of Gene_expression of Gh1 1 0.01 0 0.75 5.00
35 INT266100 Binding of COMT and SH2B2 1 0.25 1.22 0.74 5.00
36 INT266108 Binding of COMT and HPS1 1 0.23 1.21 0.74 5.00
37 INT222432 Binding of Tlr4 and Cd14 1 0.02 0.74 0.71 5.00
38 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71 5.00
39 INT107910 Binding of Tnfrsf11b and Tnfsf11 6 0.30 5.88 0.7 5.00
40 INT32715 Prl Regulation of Localization of LH 2 0.34 0.09 0.68 5.00
41 INT60283 Positive_regulation of Gnrh1 Regulation of LH 2 0.31 0 0.68 5.00
42 INT222552 Abat Regulation of Gene_expression of Gh1 1 0.00 0 0.67 5.00
43 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66 5.00
44 INT222492 Ngf Positive_regulation of Gene_expression of Prl 1 0.24 0 0.62 5.00
45 INT3617 Trh Regulation of Localization of Gh1 3 0.65 0.55 0.62 5.00
46 INT27067 Crh Positive_regulation of Localization of Avp 3 0.18 0.46 0.61 5.00
47 INT32747 Avp Positive_regulation of Localization of Pomc 4 0.16 1.92 0.61 5.00
48 INT222521 Vip Positive_regulation of Localization of Ngf 1 0.14 0.08 0.6 5.00
49 INT60536 Gnrh1 Positive_regulation of Localization of Prl 2 0.22 1.12 0.6 5.00
50 INT222554 Il1a Positive_regulation of Localization of Ngf 1 0.02 0.07 0.6 5.00
51 INT222524 Abat Negative_regulation of Localization of Trh 1 0.02 0.16 0.51 5.00
52 INT222490 Npy Positive_regulation of Localization of Gh1 1 0.02 0.06 0.41 5.00
53 INT222418 Tlr4 Positive_regulation of Gene_expression of Il1a 1 0.00 0.31 0.39 5.00
54 INT172125 Binding of Tnfrsf11b and Tnfrsf11a 2 0.17 2.12 0.39 5.00
55 INT3616 Trh Positive_regulation of Localization of Gh1 4 0.73 0.49 0.36 5.00
56 INT222441 Tlr4 Positive_regulation of Gene_expression of Tac1 1 0.00 0.39 0.32 5.00
57 INT188804 S100a8 Positive_regulation of Gene_expression of Tnfsf11 1 0.00 0.7 0.31 5.00
58 INT222464 Col4a2 Regulation of Localization of Prl 1 0.03 0.32 0.3 5.00
59 INT222529 Binding of Trh and Vip 1 0.07 0.09 0.29 5.00
60 INT126696 Binding of Crhr1 and Crh 3 0.50 0.44 0.29 5.00
61 INT222428 Negative_regulation of Tlr4 Positive_regulation of Il6 1 0.01 0.26 0.27 5.00
62 INT222412 Cd14 Negative_regulation of Binding of Tlr4 1 0.02 0.26 0.27 5.00
63 INT222440 Tlr4 Positive_regulation of Localization of Pomc 1 0.01 0.35 0.27 5.00
64 INT222427 Il6 Positive_regulation of Localization of Pomc 1 0.02 0.27 0.26 5.00
65 INT224458 TNF Positive_regulation of Gene_expression of Nfkb1 2 0.34 1.47 0.26 5.00
66 INT222422 Tlr4 Positive_regulation of Il6 1 0.01 0.25 0.26 5.00
67 INT222467 Gh1 Positive_regulation of Prl 1 0.04 0.52 0.26 5.00
68 INT188802 Il1 Negative_regulation of Gene_expression of Col7a1 1 0.00 0.71 0.26 5.00
69 INT222557 Gal Positive_regulation of Gene_expression of Vip 1 0.06 0.07 0.25 5.00
70 INT222421 Tlr4 Negative_regulation of Localization of Prl 1 0.02 0.45 0.25 5.00
71 INT222563 Vip Positive_regulation of Gene_expression of Il6 1 0.05 0.38 0.25 5.00
72 INT222560 Calca Positive_regulation of Gene_expression of Il6 1 0.06 0.39 0.25 5.00
73 INT222540 Mzb1 Positive_regulation of Gene_expression of Il6 1 0.03 0.38 0.25 5.00
74 INT222561 Gnrh1 Positive_regulation of Prl 1 0.15 0.38 0.22 5.00
75 INT207845 Binding of INS and Hypism 3 0.04 2.88 0.22 5.00
76 INT312517 Rapgef1 Negative_regulation of Rbp4 1 0.01 0.9 0.22 5.00
77 INT222527 Gal Regulation of Vip 1 0.03 0.05 0.22 5.00
78 INT222566 Agt Positive_regulation of Localization of Prl 1 0.08 0.23 0.21 5.00
79 INT188801 Il6 Positive_regulation of Positive_regulation of Tnfsf11 1 0.06 0.46 0.21 5.00
80 INT318357 Binding of Pmp2 and Adcy3 1 0.06 0.26 0.2 5.00
81 INT222482 Lep Positive_regulation of Localization of Gh1 1 0.02 1.02 0.2 5.00
82 INT318356 Positive_regulation of Binding of Slc10a7 and Adcy3 1 0.17 0.26 0.2 5.00
83 INT318358 Positive_regulation of Binding of Pmp2 and Adcy3 1 0.08 0.26 0.2 5.00
84 INT318359 Binding of Slc10a7 and Adcy3 1 0.12 0.26 0.2 5.00
85 INT222568 Vip Negative_regulation of Transcription of Nos2 1 0.06 0.3 0.19 5.00
86 INT222543 Il1a Regulation of Chat 1 0.01 0.64 0.19 5.00
87 INT222525 Il1a Regulation of Localization of Gh1 1 0.00 0.64 0.19 5.00
88 INT222499 Il10 Regulation of Positive_regulation of Hpse 1 0.00 0.8 0.19 5.00
89 INT222473 Mzb1 Negative_regulation of Transcription of Nos2 1 0.04 0.29 0.19 5.00
90 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 5.00
91 INT222494 Negative_regulation of Il1a Negative_regulation of Positive_regulation of Il6 1 0.00 0.79 0.19 5.00
92 INT222531 Il6 Positive_regulation of Hpse 1 0.00 0.61 0.18 5.00
93 INT222661 IFNA1 Positive_regulation of Gene_expression of Nos1 1 0.01 0.25 0.18 5.00
94 INT222414 Tlr4 Positive_regulation of Hpse 1 0.00 0.61 0.18 5.00
95 INT222470 Prl Regulation of Gnrh1 1 0.14 0.09 0.18 5.00
96 INT148531 Binding of TNFRSF11A and Tnfsf11 2 0.08 1.77 0.17 5.00
97 INT1394 Binding of Prl and LH 3 0.36 0 0.17 5.00
98 INT222443 INCENP Positive_regulation of Localization of Pomc 1 0.00 0.75 0.17 5.00
99 INT222426 Lif Positive_regulation of Localization of Pomc 1 0.02 0.75 0.17 5.00
100 INT222505 Gene_expression of Crh Negative_regulation of Gene_expression of Hpse 1 0.02 0.55 0.17 5.00
101 INT222509 Ghrh Positive_regulation of Localization of Prl 1 0.28 0.23 0.16 5.00
102 INT266101 Binding of HPS1 and SH2B2 1 0.17 0.67 0.16 5.00
103 INT222430 Il11 Positive_regulation of Localization of Pomc 1 0.01 0.69 0.16 5.00
104 INT222548 Il11 Positive_regulation of Transcription of Pomc 1 0.03 0.7 0.16 5.00
105 INT266107 Binding of MET and SH2B2 1 0.02 0.67 0.15 5.00
106 INT222420 Tlr4 Positive_regulation of Positive_regulation of Hpse 1 0.00 0.67 0.15 5.00
107 INT39154 Crh Positive_regulation of Avp 2 0.11 0.15 0.14 5.00
108 INT222673 Gnrh1 Negative_regulation of Gnrh1 Positive_regulation of Prl 1 0.08 0.21 0.14 5.00
109 INT222551 Il6 Positive_regulation of Positive_regulation of Hpse 1 0.01 0.5 0.13 5.00
110 INT222465 Binding of Calcrl and Rxfp2 1 0.02 0 0.12 5.00
111 INT222546 Mzb1 Positive_regulation of Localization of Prl 1 0.10 0.17 0.12 5.00
112 INT222549 Pomc Positive_regulation of Gnrh1 1 0.13 0 0.12 5.00
113 INT222507 Igf1 Positive_regulation of Localization of Edn3 1 0.05 0 0.11 5.00
114 INT222472 Lep Positive_regulation of Localization of Cartpt 1 0.05 0 0.11 5.00
115 INT222503 Agt Positive_regulation of Localization of Gh1 1 0.02 0.23 0.11 5.00
116 INT222558 Mzb1 Regulation of Localization of Prl 1 0.13 0.14 0.1 5.00
117 INT220149 Binding of IGF1 and IGFALS 2 0.39 0.44 0.1 5.00
118 INT222501 Cartpt Negative_regulation of Localization of Prl 1 0.08 0 0.1 5.00
119 INT222553 Binding of Sdc1 and Egf 1 0.02 0 0.1 5.00
120 INT222517 Calca Positive_regulation of Localization of Gh1 1 0.03 0 0.09 5.00
121 INT222442 Tlr4 Positive_regulation of Gene_expression of INCENP 1 0.00 0.34 0.09 5.00
122 INT222425 Mif Regulation of Tlr4 1 0.01 0.24 0.09 5.00
123 INT222483 Trh Regulation of Gene_expression of Gh1 1 0.03 0 0.09 5.00
124 INT295005 Binding of TNFRSF11A and Tnfsf11 3 0.20 2.02 0.09 5.00
125 INT222484 Pomc Positive_regulation of Transcription of Prl 1 0.14 0 0.09 5.00
126 INT222511 Il1a Positive_regulation of Gene_expression of Fst 1 0.01 0.32 0.08 5.00
127 INT270201 Binding of CD28 and Cd86 1 0.10 0.58 0.08 5.00
128 INT1388 Binding of Prl and Gnrh1 3 0.35 0.17 0.08 5.00
129 INT222545 Lep Negative_regulation of Nmb 1 0.04 0.52 0.08 5.00
130 INT270203 Binding of CD28 and Apc 1 0.04 0.58 0.08 5.00
131 INT8092 Npy Regulation of Localization of Gnrh1 2 0.30 0.08 0.08 5.00
132 INT222514 Mif Regulation of Localization of Il6 1 0.04 0.23 0.08 5.00
133 INT222506 Gnrh1 Regulation of Localization of Prl 1 0.20 0.16 0.08 5.00
134 INT222662 Il1a Positive_regulation of Gene_expression of INCENP 1 0.00 0.32 0.08 5.00
135 INT270197 Binding of Apc and Cd86 1 0.02 0.58 0.08 5.00
136 INT270202 Binding of CD28 and Cd80 1 0.09 0.58 0.08 5.00
137 INT270198 Binding of Apc and Cd80 1 0.02 0.58 0.08 5.00
138 INT295003 Binding of Tnfrsf11b and Tnfsf11 3 0.22 1.85 0.08 5.00
139 INT222489 Npr2 Positive_regulation of Pde5a 1 0.00 0.16 0.07 5.00
140 INT222466 Gnrh1 Regulation of Prl 1 0.14 1.16 0.07 5.00
141 INT278059 XRCC1 Positive_regulation of Gene_expression of IL2 1 0.01 1.06 0.07 5.00
142 INT222429 Nps Positive_regulation of Pde5a 1 0.00 0.16 0.07 5.00
143 INT32745 Crh Positive_regulation of Localization of Pomc 2 0.16 0.49 0.07 5.00
144 INT174901 Binding of GSPT2 and GTSE1 1 0.01 1.28 0.07 5.00
145 INT222416 Tlr4 Positive_regulation of Gene_expression of Inhba 1 0.00 0.29 0.06 5.00
146 INT222488 Gal Positive_regulation of Gene_expression of Prl 1 0.05 0.05 0.06 5.00
147 INT222479 Binding of Ramp1 and Rxfp2 1 0.01 0 0.06 5.00
148 INT222431 Tlr4 Positive_regulation of Gene_expression of Fst 1 0.01 0.29 0.06 5.00
149 INT222533 Mzb1 Positive_regulation of Gene_expression of Gh1 1 0.03 0 0.06 5.00
150 INT270199 Icos Positive_regulation of Localization of Il10 1 0.03 0.63 0.06 5.00
151 INT222478 Binding of Calca and Rxfp2 1 0.02 0 0.06 5.00
152 INT222513 Mzb1 Positive_regulation of Localization of Gh1 1 0.03 0 0.06 5.00
153 INT222570 Cnp Positive_regulation of Localization of Gh1 1 0.03 0 0.06 5.00
154 INT222663 Mzb1 Positive_regulation of Localization of VEGFA 1 0.02 0 0.05 5.00
155 INT222463 Inhba Positive_regulation of Gene_expression of Fst 1 0.01 0 0.05 5.00
156 INT222520 Mzb1 Positive_regulation of Gene_expression of Fst 1 0.04 0 0.05 5.00
157 INT222476 Gnrh1 Negative_regulation of Gene_expression of Fst 1 0.04 0 0.05 5.00
158 INT260728 Binding of Samsn1 and NAFLD2 1 0.00 1.15 0.05 5.00
159 INT222544 Binding of Ucn and Crh 1 0.02 0 0.05 5.00
160 INT222508 Ghrh Regulation of Localization of LH 1 0.07 0 0.05 5.00
161 INT222487 Trh Negative_regulation of Nmb 1 0.05 0.26 0.05 5.00
162 INT258084 Binding of IL6 and Regulation of Gene_expression of INS 1 0.11 0.62 0.05 5.00
163 INT222512 Nppa Positive_regulation of Localization of LH 1 0.02 0 0.05 5.00
164 INT222664 Il6 Positive_regulation of Localization of VEGFA 1 0.01 0 0.05 5.00
165 INT222559 Binding of Ramp3 and Ramp1 1 0.02 0 0.05 5.00
166 INT222485 Binding of Iapp and Ramp1 1 0.09 0 0.05 5.00
167 INT321891 Dkk1 Negative_regulation of Wnt2 1 0.12 0.94 0.05 5.00
168 INT323056 LDLR Regulation of HSD11B1 1 0.01 1.2 0.05 5.00
169 INT222567 Negative_regulation of Gh1 Negative_regulation of Ghrh 1 0.03 0.19 0.04 5.00
170 INT222498 Ghrh Positive_regulation of Gene_expression of Ghrl 1 0.10 0.19 0.04 5.00
171 INT207846 Hypism Regulation of INS 1 0.06 1.14 0.04 5.00
172 INT303393 Binding of Jag1 and Tceb2 1 0.03 0.29 0.04 5.00
173 INT222417 Ucn Positive_regulation of Localization of Pomc 1 0.01 0 0.04 5.00
174 INT295006 Binding of TNFRSF11A and Tnfrsf11b 2 0.10 1.6 0.04 5.00
175 INT222534 Gnrh1 Positive_regulation of Localization of Lep 1 0.07 0 0.04 5.00
176 INT303389 Binding of Jag1 and Cul5 1 0.20 0.29 0.04 5.00
177 INT222497 Negative_regulation of Gh1 Negative_regulation of Ghrl 1 0.01 0.2 0.04 5.00
178 INT321890 Slc3a2 Regulation of Dkk1 1 0.01 0.93 0.04 5.00
179 INT270206 Hdl1 Positive_regulation of Gene_expression of IL2 1 0.01 0.35 0.03 5.00
180 INT222562 Trh Regulation of Localization of LH 1 0.04 0 0.03 5.00
181 INT266105 SH2B2 Positive_regulation of Gene_expression of HPS1 1 0.24 0.62 0.03 5.00
182 INT222468 Nmb Positive_regulation of Localization of Trh 1 0.05 0.28 0.03 5.00
183 INT222532 Anxa1 Negative_regulation of Localization of Gh1 1 0.01 0.14 0.03 5.00
184 INT222469 Binding of Ucn and Crhr2 1 0.00 0 0.03 5.00
185 INT222477 Mzb1 Positive_regulation of Gene_expression of Prl 1 0.10 0.1 0.03 5.00
186 INT222565 Crh Positive_regulation of Transcription of Pomc 1 0.10 0.35 0.03 5.00
187 INT222538 Anxa1 Negative_regulation of Localization of Prl 1 0.04 0.14 0.03 5.00
188 INT222564 Mzb1 Regulation of Localization of Gh1 1 0.01 0 0.03 5.00
189 INT222475 Anxa1 Negative_regulation of Localization of LH 1 0.01 0.14 0.03 5.00
190 INT222510 Nmb Positive_regulation of Trh 1 0.05 0.28 0.03 5.00
191 INT222500 Avp Positive_regulation of Transcription of Pomc 1 0.17 0.35 0.03 5.00
192 INT303406 Binding of NPAT and Myo1f 1 0.06 0 0 5.00
193 INT327052 Gene_expression of Akt1 Positive_regulation of Gene_expression of Myod1 1 0.19 0.18 0 5.00
194 INT303387 Binding of Laptm5 and Gopc 1 0.01 0 0 5.00
195 INT222536 Ghrl Positive_regulation of Transcription of Pou1f1 1 0.03 0.13 0 5.00
196 INT300696 Sirt1 Regulation of Cyb5r3 1 0.03 0 0 5.00
197 INT354097 Timp1 Negative_regulation of Localization of NFKB2 1 0.04 0.94 0 5.00
198 INT222571 Il11 Regulation of Localization of Prl 1 0.03 0.06 0 5.00
199 INT303397 Binding of Jag1 and Gopc 1 0.13 0 0 5.00
200 INT278495 IGFBP2 Positive_regulation of Gene_expression of IGF1 1 0.20 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Nutritional Deficiencies. They are ordered first by their pain relevance and then by number of times they were reported in Nutritional Deficiencies. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT355463 Gene_expression of SPRED1 1 0.56 6.96 0.24 100.00
2 INT55276 Regulation of Positive_regulation of Sct 3 0.44 0.92 0.59 100.00
3 INT9473 Binding of MUC1 66 0.48 46.77 2.36 100.00
4 INT58432 Positive_regulation of Gsr 12 0.70 9.4 1.94 99.86
5 INT355461 Localization of SPRED1 1 0.63 3.48 0.04 99.80
6 INT355462 Negative_regulation of SPRED1 1 0.36 1.34 0.16 99.80
7 INT355460 Positive_regulation of SPRED1 1 0.42 0.37 0 99.80
8 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 99.44
9 INT94464 Negative_regulation of Hand1 44 0.41 31.5 12.39 98.68
10 INT288 Positive_regulation of Sct 88 0.70 32.83 24.5 98.62
11 INT5127 Localization of Lhb 488 0.80 50.48 162.66 98.56
12 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 98.40
13 INT131187 Regulation of Gene_expression of IGF1 18 0.62 11.18 3.05 98.32
14 INT11729 Regulation of IGF1 71 0.61 44.58 9.71 98.32
15 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 98.12
16 INT5113 Binding of MROS 4 0.31 2.52 0.17 97.88
17 INT16205 Localization of ras 25 0.73 18.99 1.85 97.60
18 INT15557 Regulation of Localization of Alb 13 0.50 5.71 2.91 97.12
19 INT164975 Binding of ELN 6 0.35 6.38 0.64 97.10
20 INT22871 Gene_expression of ELN 30 0.68 14.86 1.33 96.62
21 INT249469 Gene_expression of BMF 1 0.54 1.53 0 96.56
22 INT16130 Binding of IGF1 67 0.48 27.43 2.95 96.56
23 INT5008 Localization of Calca 204 0.81 80.35 125.16 96.36
24 INT125804 Localization of Pth 9 0.69 3.93 0.29 96.36
25 INT7678 Localization of Alb 142 0.81 80.93 22.49 95.88
26 INT135629 Binding of COMT 33 0.48 16.68 19.37 94.96
27 INT14572 Binding of INS 205 0.48 175.43 13.38 94.88
28 INT15458 Gene_expression of NPY 50 0.76 22.67 23.03 94.60
29 INT75908 Regulation of LEP 77 0.60 60.16 15.19 94.20
30 INT252 Localization of GH1 529 0.80 227.4 122.05 94.12
31 INT1047 Negative_regulation of LH 314 0.59 53.71 135.89 93.36
32 INT10783 Negative_regulation of Gnrh1 24 0.59 7.9 6.2 93.12
33 INT13321 Negative_regulation of Hpse 11 0.56 4.64 3.39 93.12
34 INT55582 Positive_regulation of Negative_regulation of Hpse 2 0.13 0.56 0.32 93.12
35 INT231953 Regulation of Myh1 3 0.07 0.23 0 92.32
36 INT303363 Positive_regulation of Regulation of Myh1 1 0.08 0.23 0 92.32
37 INT249471 Binding of BMF 1 0.30 1.3 0 91.72
38 INT5454 Localization of CRH 124 0.79 79.18 41.53 91.28
39 INT5455 Negative_regulation of Localization of CRH 16 0.49 7.31 6.41 91.28
40 INT303355 Positive_regulation of Localization of Myo1f 1 0.10 0.22 0 91.28
41 INT303375 Positive_regulation of Myo1f 1 0.08 0.22 0 91.28
42 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32 91.00
43 INT195575 Localization of Myo1f 2 0.12 0.28 0.03 90.84
44 INT9677 Negative_regulation of Gene_expression of GH1 46 0.48 23.32 3.68 89.56
45 INT439 Localization of Gnrh1 976 0.81 100.96 363.25 88.88
46 INT4289 Positive_regulation of Localization of Gnrh1 202 0.70 12.3 84.01 88.88
47 INT5864 Localization of IL36RN 19 0.44 14.5 6.87 88.88
48 INT2379 Positive_regulation of Localization of LH 349 0.70 27.86 144.53 88.68
49 INT20378 Localization of Hand1 53 0.71 41.96 13.31 88.64
50 INT1045 Localization of LH 1211 0.81 87.04 456.25 88.36
51 INT112017 Regulation of Hand2 77 0.36 62.23 18.04 88.36
52 INT173505 Localization of Hand2 63 0.57 45.32 13.66 88.36
53 INT188754 Localization of AGRP 15 0.74 8.88 0.6 87.80
54 INT7397 Negative_regulation of Localization of GNRH1 86 0.59 15.45 29.78 87.76
55 INT84250 Positive_regulation of IDUA 8 0.56 15.89 0.62 87.44
56 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 87.40
57 INT241863 Binding of SLC40A1 4 0.28 3.86 0.22 87.28
58 INT241866 Binding of HAMP 2 0.47 1.65 0.07 87.28
59 INT5100 Positive_regulation of Ghrh 100 0.64 24.2 30.21 86.88
60 INT53747 Positive_regulation of Cyp2e1 34 0.70 29.03 13.39 86.48
61 INT115374 Positive_regulation of Gene_expression of Cyp2e1 6 0.67 4.36 1.27 86.48
62 INT62580 Gene_expression of Cyp2e1 31 0.78 15.4 11.08 86.08
63 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9 85.84
64 INT150330 Gene_expression of BMPR2 7 0.29 4.22 0.34 85.40
65 INT6441 Positive_regulation of CRH 98 0.69 57.22 24.12 85.32
66 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 85.08
67 INT19844 Negative_regulation of Gene_expression of Lhb 12 0.51 3.19 2.97 85.08
68 INT7832 Localization of Cck 39 0.81 6.81 26.54 84.92
69 INT7532 Negative_regulation of Gene_expression of Ifng 33 0.59 18.56 13.14 84.40
70 INT7224 Positive_regulation of Gene_expression of Lhb 18 0.45 10.22 3.4 84.36
71 INT189604 Negative_regulation of BMPR2 2 0.26 0.95 0.15 84.20
72 INT192082 Localization of BMPR2 1 0.32 0.55 0.15 84.20
73 INT35086 Positive_regulation of Gene_expression of Ifng 40 0.69 22.55 18.35 84.16
74 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6 84.16
75 INT2261 Gene_expression of Lhb 121 0.77 42.78 26.04 83.96
76 INT34741 Positive_regulation of Gene_expression of GH1 58 0.67 35.06 7.8 83.88
77 INT15172 Positive_regulation of Itgam 45 0.67 23.54 10.3 83.52
78 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 83.08
79 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22 83.04
80 INT187726 Positive_regulation of Localization of LEP 5 0.50 5.31 0.41 83.04
81 INT34777 Localization of IGF1 82 0.80 42.68 8.62 82.44
82 INT58145 Positive_regulation of Localization of Tnf 20 0.67 13.33 5.44 82.36
83 INT35406 Localization of Tnf 94 0.81 64.63 31.65 81.72
84 INT65356 Localization of LEP 46 0.79 41.17 5.43 80.88
85 INT209241 Regulation of Gene_expression of pcp 3 0.39 0.81 0.72 80.40
86 INT318344 Regulation of Gene_expression of Pmp2 1 0.11 0.71 0.04 80.40
87 INT318353 Regulation of Gene_expression of Slc10a7 1 0.23 0.71 0.04 80.40
88 INT2040 Positive_regulation of CYP2B6 95 0.69 34.3 25.6 80.32
89 INT7090 Gene_expression of pcp 50 0.66 13.54 8.96 79.60
90 INT207002 Gene_expression of Slc10a7 21 0.39 2.33 2.59 79.60
91 INT103048 Gene_expression of Pmp2 7 0.16 2.73 1.18 79.60
92 INT296385 Binding of IDUA 12 0.39 20.73 0.93 78.72
93 INT153115 Protein_catabolism of SPINK1 2 0.90 2.46 1.11 78.68
94 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31 78.56
95 INT7925 Transcription of Ghrh 13 0.67 2.36 6.77 78.24
96 INT81795 Negative_regulation of AGRP 23 0.41 10.93 0.87 77.84
97 INT188368 Gene_expression of HAVCR1 5 0.52 0.99 0.16 77.76
98 INT23744 Protein_catabolism of Ctrc 8 0.62 1.93 2.19 77.72
99 INT100861 Binding of CRP 179 0.48 175.2 26.45 76.52
100 INT63164 Negative_regulation of Cst7 51 0.50 18.48 20.3 75.60
101 INT16530 Gene_expression of Ghrh 45 0.77 6.22 13.44 75.60
102 INT89113 Regulation of Cftr 11 0.62 6.83 4.01 75.40
103 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 75.12
104 INT21379 Transcription of Crh 65 0.72 15.64 27.92 75.00
105 INT22338 Negative_regulation of Transcription of Crh 11 0.43 2.09 5.24 75.00
106 INT438 Gene_expression of Crh 376 0.78 159.11 169.17 75.00
107 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 75.00
108 INT683 Positive_regulation of AVP 173 0.70 74.55 46.41 75.00
109 INT7692 Positive_regulation of PENK 71 0.70 20.34 32.54 75.00
110 INT5503 Negative_regulation of Gene_expression of Crh 38 0.59 16.82 21.34 75.00
111 INT82079 Positive_regulation of Lep 79 0.70 40 11.07 75.00
112 INT99020 Gene_expression of Nlrp3 23 0.75 18.86 4.4 75.00
113 INT103487 Positive_regulation of Positive_regulation of Lep 9 0.67 4.08 2.38 75.00
114 INT99034 Negative_regulation of CYP11A1 2 0.41 0.92 0.1 75.00
115 INT99021 Positive_regulation of Penk-rs 1 0.01 0.07 0 75.00
116 INT99035 Regulation of Negative_regulation of CYTL1 1 0.44 0.07 0 75.00
117 INT99032 Negative_regulation of CYTL1 1 0.41 0.07 0 75.00
118 INT99018 Regulation of Transcription of Nlrp3 1 0.00 0.07 0 75.00
119 INT99031 Transcription of CYTL1 1 0.52 0.07 0 75.00
120 INT99030 Transcription of CYP11A1 1 0.52 0.07 0 75.00
121 INT99016 Negative_regulation of Positive_regulation of Penk-rs 1 0.01 0.07 0 75.00
122 INT99022 Regulation of Gene_expression of Nlrp3 1 0.00 0.07 0 75.00
123 INT99017 Transcription of Nlrp3 1 0.00 0.07 0 75.00
124 INT99033 Regulation of Negative_regulation of CYP11A1 1 0.44 0.07 0 75.00
125 INT99019 Regulation of Positive_regulation of Penk-rs 1 0.01 0.07 0 75.00
126 INT73641 Regulation of Lep 45 0.62 26.2 12.59 74.96
127 INT159128 Localization of Nps 12 0.69 5.18 1.74 74.76
128 INT63057 Regulation of CYP3A4 31 0.61 5.75 6.92 74.32
129 INT163157 Binding of BMS1 3 0.42 3.6 1.77 74.32
130 INT239094 Negative_regulation of Binding of GH1 2 0.34 1.61 0.06 73.96
131 INT105162 Gene_expression of Ad 47 0.12 46.53 1.83 73.60
132 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 73.40
133 INT9683 Binding of GH1 57 0.47 21.14 5.99 73.36
134 INT1562 Localization of Crh 499 0.81 126.74 236.68 73.28
135 INT1438 Localization of Pomc 360 0.81 101.26 116.47 72.72
136 INT860 Regulation of ALB 48 0.60 25.11 8.95 72.40
137 INT215031 Localization of Ppy 2 0.23 1.73 0.37 71.96
138 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 71.72
139 INT39587 Gene_expression of CP 42 0.65 31.48 11.87 71.16
140 INT28312 Gene_expression of ABCA1 85 0.72 37.69 9.27 71.16
141 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 70.60
142 INT126734 Positive_regulation of MDM2 8 0.49 5.56 0 70.60
143 INT279351 Regulation of IDUA 2 0.36 1.71 0 70.24
144 INT320987 Transcription of Gc 1 0.07 0.36 0 70.24
145 INT14714 Negative_regulation of NPY 10 0.58 4.41 4.52 68.36
146 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 68.20
147 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62 67.72
148 INT140637 Negative_regulation of IFI27 11 0.40 9.48 0.69 67.72
149 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 67.52
150 INT273867 Binding of Jag1 18 0.45 3.14 0.25 66.60
151 INT294932 Negative_regulation of Gc 6 0.17 3.38 0.71 66.48
152 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67 66.32
153 INT7205 Positive_regulation of HBG1 65 0.69 40.35 6.37 66.32
154 INT9895 Binding of GHR 18 0.36 4.8 5.65 66.28
155 INT13415 Positive_regulation of Hpse 58 0.70 24.9 25.53 66.04
156 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 64.96
157 INT57644 Regulation of SPINK1 7 0.47 15.19 3.64 64.44
158 INT38970 Regulation of Ctrc 5 0.11 2.75 1.43 64.44
159 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 64.24
160 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 64.20
161 INT139678 Positive_regulation of Hspb8 23 0.68 23.94 1.85 64.08
162 INT546 Binding of ALB 311 0.48 85.98 60.14 63.36
163 INT9840 Positive_regulation of F7 17 0.57 17.83 2.08 62.24
164 INT287790 Positive_regulation of Gene_expression of F7 1 0.49 1.55 0.2 62.24
165 INT100195 Negative_regulation of SPANXB1 5 0.48 2.7 0.82 62.12
166 INT326623 Binding of Ttr 2 0.35 4.76 0.46 62.00
167 INT221999 Gene_expression of F7 2 0.65 2.1 0.2 61.60
168 INT111461 Positive_regulation of hb 30 0.38 21.08 2.1 60.76
169 INT122812 Gene_expression of SNRNP70 130 0.75 67 12.5 60.48
170 INT240281 Positive_regulation of IGFALS 11 0.31 10.44 0.56 59.44
171 INT233560 Regulation of Sbp 3 0.21 1.67 0.25 57.88
172 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38 56.96
173 INT84826 Negative_regulation of ACD 6 0.50 4.02 0.55 55.04
174 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17 54.80
175 INT874 Positive_regulation of Gh1 244 0.70 27.17 97.98 54.40
176 INT38990 Negative_regulation of IDUA 12 0.59 5.04 1.33 54.40
177 INT278065 Negative_regulation of Phosphorylation of IFNA1 2 0.39 0.68 0.31 54.04
178 INT139329 Phosphorylation of IFNA1 24 0.79 16.19 5.95 53.52
179 INT124211 Protein_catabolism of IGF1 2 1.00 1.29 0.63 53.28
180 INT132586 Negative_regulation of Hand2 40 0.30 26.58 9.28 52.68
181 INT90372 Negative_regulation of Hrec 12 0.03 11.73 4.74 52.68
182 INT268223 Positive_regulation of Cldn4 1 0.05 0.35 0.03 52.16
183 INT179429 Positive_regulation of Gene_expression of pcp 3 0.49 1.64 1.36 51.56
184 INT94467 Positive_regulation of Hand1 71 0.58 59 16.96 50.92
185 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22 50.60
186 INT10147 Gene_expression of Serpinc1 28 0.76 17.73 5.77 50.00
187 INT38989 Gene_expression of IDUA 22 0.78 16.99 1.26 48.88
188 INT18462 Positive_regulation of Pgc 29 0.57 22.55 3.24 47.96
189 INT14701 Negative_regulation of IFNA1 118 0.54 84.19 20.08 47.24
190 INT222005 Regulation of HPS1 2 0.33 3.3 0.6 46.56
191 INT266126 Regulation of SH2B2 1 0.30 0.84 0.27 45.92
192 INT145 Negative_regulation of H1 12 0.39 5.68 5.08 45.88
193 INT303349 Positive_regulation of Jag1 5 0.57 1.23 0 45.60
194 INT11937 Localization of Il6 228 0.81 139.83 64.39 44.68
195 INT163581 Localization of Lep 27 0.79 18.99 4.08 44.68
196 INT23188 Localization of Serpine1 22 0.79 16.06 1.96 44.68
197 INT227273 Localization of Adipoq 22 0.72 18.04 1.72 44.68
198 INT330707 Localization of Anxa2 1 0.02 1.13 0 44.68
199 INT940 Negative_regulation of Ptgs1 219 0.59 104.34 95.97 44.28
200 INT53020 Positive_regulation of ACSM3 9 0.58 11.03 2.73 43.20
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