D:Oculopharyngeal Muscular Dystrophy

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pChart

Disease Term
Synonyms Dystrophies Oculopharyngeal Muscular, DYSTROPHY OCULOPHARYNGEAL MUSCULAR, Muscular Dystrophies Oculopharyngeal, Oculopharyngeal Muscular Dystrophies
Documents 9
Hot Single Events 8
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Oculopharyngeal Muscular Dystrophy. They are ordered first by their relevance to Oculopharyngeal Muscular Dystrophy and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT331966 Binding of DES and SACM1L 1 0.01 1.86 0.36 5.00
2 INT302676 Binding of OPA1 and MFN2 1 0.46 1.12 0.14 5.00
3 INT302675 Binding of OPA1 and PLAA 1 0.15 0.73 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Oculopharyngeal Muscular Dystrophy. They are ordered first by their pain relevance and then by number of times they were reported in Oculopharyngeal Muscular Dystrophy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT72589 Binding of PABPN1 1 0.28 1.2 0.09 100.00
2 INT124673 Phosphorylation of PABPN1 1 0.54 0.75 0.21 100.00
3 INT274203 Positive_regulation of PABPN1 1 0.16 2.41 0.37 100.00
4 INT15367 Gene_expression of OPA1 35 0.67 24.9 5.45 92.04
5 INT331969 Regulation of Gene_expression of MYOT 1 0.43 2.22 0.27 90.24
6 INT179320 Regulation of LDB3 3 0.37 1.55 0.14 90.24
7 INT331970 Regulation of Regulation of LDB3 1 0.37 1.12 0.14 90.24
8 INT331973 Gene_expression of MYOT 4 0.64 3.83 0.4 88.00
9 INT272511 Positive_regulation of DMPK 8 0.54 6.85 0.72 77.80
10 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 73.28
11 INT159409 Gene_expression of PLAA 2 0.54 6.14 0.89 55.00
12 INT302683 Negative_regulation of PLAA 1 0.15 0.4 0.13 23.20
13 INT17041 Gene_expression of PER1 24 0.66 5.31 7.12 18.16
14 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 9.76
15 INT180497 Binding of MRI1 45 0.42 28.35 14.77 6.32
16 INT264998 Regulation of Binding of MRI1 1 0.31 1.34 0.27 6.32
17 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
18 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 5.00
19 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 5.00
20 INT171666 Regulation of GOPC 117 0.39 40.41 15.47 5.00
21 INT70265 Regulation of MRI1 42 0.39 30.95 14.18 5.00
22 INT14207 Gene_expression of DNM2 20 0.67 5.76 7.64 5.00
23 INT33854 Localization of OPA1 19 0.65 10.55 5.04 5.00
24 INT34870 Positive_regulation of OPA1 18 0.59 10.66 5 5.00
25 INT57274 Positive_regulation of Gene_expression of COL7A1 50 0.69 24.19 4.72 5.00
26 INT32933 Gene_expression of GNAS 57 0.32 10.58 4.03 5.00
27 INT24883 Regulation of OPA1 14 0.45 9.73 3.44 5.00
28 INT5913 Binding of OPA1 12 0.41 9.33 2.92 5.00
29 INT6508 Gene_expression of RYR1 34 0.77 11.11 2.04 5.00
30 INT17094 Negative_regulation of SLC25A4 3 0.41 3.82 1.52 5.00
31 INT71918 Gene_expression of ACTA1 16 0.75 7.73 1.45 5.00
32 INT74550 Negative_regulation of SUCLA2 5 0.41 3.6 1.24 5.00
33 INT52460 Localization of SUCLA2 5 0.67 2.5 0.86 5.00
34 INT17246 Negative_regulation of POLG 16 0.56 9.69 0.79 5.00
35 INT19047 Localization of SLC25A4 5 0.73 2.73 0.57 5.00
36 INT94347 Gene_expression of DYSF 4 0.75 3.25 0.41 5.00
37 INT251828 Negative_regulation of C10orf2 3 0.37 2.87 0.41 5.00
38 INT211586 Regulation of DMPK 6 0.31 2.11 0.33 5.00
39 INT284528 Negative_regulation of POLG2 2 0.17 2.19 0.33 5.00
40 INT224340 Localization of TYMP 3 0.62 2.86 0.3 5.00
41 INT123637 Gene_expression of LGMD2I 2 0.08 1.7 0.29 5.00
42 INT155170 Negative_regulation of Localization of SUCLA2 2 0.38 1.26 0.28 5.00
43 INT260581 Binding of DMPK 7 0.43 5.09 0.28 5.00
44 INT301935 Gene_expression of UCK2 5 0.13 4.4 0.27 5.00
45 INT138715 Gene_expression of POLG 12 0.66 6.97 0.23 5.00
46 INT175417 Binding of SACM1L 8 0.29 6.06 0.22 5.00
47 INT194332 Localization of MFN2 2 0.74 1.45 0.15 5.00
48 INT302703 Binding of PLAA 1 0.13 0.87 0.15 5.00
49 INT88416 Positive_regulation of Gene_expression of ACTA1 2 0.67 1.05 0.13 5.00
50 INT158175 Positive_regulation of Gene_expression of RYR1 2 0.48 1.35 0.13 5.00
51 INT289892 Gene_expression of SEPN1 3 0.42 1.17 0.13 5.00
52 INT331968 Positive_regulation of Gene_expression of SEPN1 1 0.31 1 0.13 5.00
53 INT331971 Positive_regulation of Gene_expression of DNM2 1 0.31 1 0.13 5.00
54 INT302679 Negative_regulation of Localization of POLG 1 0.39 0.99 0.11 5.00
55 INT302682 Localization of POLG2 1 0.67 1 0.11 5.00
56 INT302693 Localization of C10orf2 1 0.59 1 0.11 5.00
57 INT302695 Negative_regulation of Localization of C10orf2 1 0.33 1 0.11 5.00
58 INT302699 Negative_regulation of Localization of SLC25A4 1 0.38 1.01 0.11 5.00
59 INT302706 Negative_regulation of Localization of POLG2 1 0.38 1 0.11 5.00
60 INT331967 Negative_regulation of LGMD2A 1 0.06 0.48 0.11 5.00
61 INT331972 Positive_regulation of Gene_expression of DYSF 1 0.28 0.48 0.11 5.00
62 INT302692 Localization of POLG 1 0.69 0.99 0.1 5.00
63 INT272205 Positive_regulation of LGMD2I 2 0.12 2.08 0.08 5.00
64 INT302684 Negative_regulation of RRM2B 1 0.17 0.73 0.08 5.00
65 INT302686 Negative_regulation of Localization of RRM2B 1 0.38 0.73 0.08 5.00
66 INT302690 Negative_regulation of Localization of MPV17 1 0.37 0.67 0.08 5.00
67 INT302698 Negative_regulation of MPV17 1 0.16 0.67 0.08 5.00
68 INT211378 Negative_regulation of TYMP 2 0.56 1.45 0.07 5.00
69 INT302680 Localization of DGUOK 1 0.66 0.65 0.07 5.00
70 INT302681 Negative_regulation of Localization of DGUOK 1 0.38 0.65 0.07 5.00
71 INT302685 Localization of MPV17 1 0.65 0.67 0.07 5.00
72 INT302689 Negative_regulation of TK2 1 0.16 0.65 0.07 5.00
73 INT302691 Negative_regulation of Localization of SUCLG1 1 0.37 0.66 0.07 5.00
74 INT302694 Localization of RRM2B 1 0.66 0.73 0.07 5.00
75 INT302696 Negative_regulation of Localization of TK2 1 0.37 0.65 0.07 5.00
76 INT302697 Negative_regulation of DGUOK 1 0.38 0.65 0.07 5.00
77 INT302700 Localization of TK2 1 0.65 0.65 0.07 5.00
78 INT302702 Negative_regulation of SUCLG1 1 0.16 0.66 0.07 5.00
79 INT302704 Negative_regulation of Localization of TYMP 1 0.35 0.64 0.07 5.00
80 INT302705 Localization of SUCLG1 1 0.65 0.66 0.07 5.00
81 INT302687 Regulation of PLAA 1 0.19 0.24 0 5.00
82 INT302688 Transcription of OPA1 1 0.68 0.3 0 5.00
83 INT302701 Positive_regulation of PLAA 1 0.18 0 0 5.00
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