D:Onchocerciasis

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Onchocercal Dermatitis, ONCHOCERCIASES, Onchocercoma, RIVER BLINDNESS
Documents 84
Hot Single Events 12
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Onchocerciasis. They are ordered first by their relevance to Onchocerciasis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT279131 LTF Positive_regulation of CALR 1 0.03 2.39 0 87.48
2 INT218240 Binding of SAE1 and Dync1h1 1 0.00 0.17 0 50.00
3 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22 26.00
4 INT288376 IL17A Regulation of VEGFA 1 0.00 1.16 0.49 26.00
5 INT313687 Binding of BCR and IFIH1 1 0.09 0.23 0 10.32
6 INT197095 IL1B Regulation of Positive_regulation of TNF 1 0.01 0.64 0.19 5.00
7 INT175727 IL1B Regulation of VEGFA 2 0.04 0.7 0.19 5.00
8 INT197093 TNF Regulation of Positive_regulation of IL1B 1 0.01 0.64 0.19 5.00
9 INT197097 IL1B Regulation of FLT4 1 0.03 0.66 0.19 5.00
10 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 5.00
11 INT197098 TNF Regulation of FLT4 1 0.14 0.66 0.19 5.00
12 INT275896 IFN1@ Positive_regulation of Gene_expression of TH1L 1 0.09 0.37 0.08 5.00
13 INT197096 VEGFA Positive_regulation of FLT4 1 0.04 1.43 0 5.00
14 INT197099 Negative_regulation of Binding of FLT4 and VEGFA 1 0.04 1.04 0 5.00
15 INT208139 Binding of PITX1 and URI1 1 0.01 0.62 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Onchocerciasis. They are ordered first by their pain relevance and then by number of times they were reported in Onchocerciasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT9440 Binding of MSMB 4 0.38 3.66 2.61 100.00
2 INT147113 Binding of LTF 14 0.29 18.24 0.98 100.00
3 INT58365 Gene_expression of LTF 51 0.78 44.14 7.25 99.76
4 INT167056 Gene_expression of CALR 29 0.75 20.05 1.25 99.42
5 INT183207 Negative_regulation of USE1 14 0.18 10.97 4 99.36
6 INT59792 Gene_expression of STH 14 0.75 15.2 0.61 98.92
7 INT10303 Regulation of STH 16 0.60 16.14 0.95 98.44
8 INT33008 Gene_expression of Dync1h1 41 0.68 23.85 3.82 96.28
9 INT74446 Positive_regulation of Dync1h1 25 0.59 13 2.38 95.44
10 INT65642 Binding of Dync1h1 27 0.41 15.83 2.68 93.92
11 INT313688 Regulation of IFIH1 3 0.19 4.2 0.48 91.36
12 INT48418 Localization of Dync1h1 4 0.61 1.54 0.44 82.32
13 INT22095 Negative_regulation of Dync1h1 11 0.48 5.17 1.08 79.20
14 INT182438 Localization of MPG 3 0.30 1.43 0.04 78.12
15 INT91106 Negative_regulation of LTF 9 0.51 5.73 1.09 77.80
16 INT75648 Negative_regulation of CTD 4 0.07 3.91 0.25 77.80
17 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 75.00
18 INT114862 Gene_expression of BEST1 16 0.65 12.14 1.53 74.36
19 INT218247 Gene_expression of Cardf1 3 0.65 2.37 0.24 70.28
20 INT162801 Localization of CALR 7 0.73 8.69 0.6 70.20
21 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 70.00
22 INT38268 Positive_regulation of BEST1 16 0.17 14.54 1.93 69.68
23 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 69.40
24 INT140394 Regulation of Dync1h1 7 0.39 2.59 1.25 63.80
25 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 53.00
26 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 53.00
27 INT153300 Negative_regulation of Gene_expression of CRP 48 0.58 39.97 7.58 53.00
28 INT189062 Negative_regulation of NDS9 1 0.01 0.93 0 51.80
29 INT218235 Negative_regulation of Gene_expression of Dync1h1 2 0.37 0.57 0.34 50.76
30 INT99524 Gene_expression of IFIH1 34 0.64 23.38 2.24 50.72
31 INT73362 Negative_regulation of Abcb1a 46 0.59 8.78 17.81 50.00
32 INT7776 Gene_expression of Abcb1b 63 0.75 21.35 14.92 50.00
33 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68 50.00
34 INT102272 Regulation of TH1L 41 0.44 30.89 11.63 50.00
35 INT1934 Positive_regulation of Cys1 68 0.68 60.56 10.47 50.00
36 INT69306 Negative_regulation of TH1L 28 0.57 24.81 9.74 50.00
37 INT49566 Positive_regulation of LMOD1 16 0.61 5.74 5.92 50.00
38 INT60957 Negative_regulation of Abcb1b 18 0.57 6 4.73 50.00
39 INT202577 Localization of DIO2 9 0.56 1.3 2.97 50.00
40 INT182807 Localization of Cuzd1 2 0.49 1.38 0.14 49.84
41 INT182808 Phosphorylation of Cuzd1 1 0.53 0.38 0 49.24
42 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 42.04
43 INT181790 Gene_expression of FLT4 13 0.72 11.73 0.56 39.44
44 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 38.60
45 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 31.08
46 INT197105 Negative_regulation of FLT4 13 0.42 11.48 0.92 31.08
47 INT182810 Gene_expression of Cuzd1 5 0.44 1.49 0.53 29.84
48 INT297921 Regulation of Gene_expression of LTF 2 0.10 3.11 0.37 28.56
49 INT47625 Negative_regulation of IFIH1 4 0.51 1.68 0.39 24.72
50 INT15357 Positive_regulation of STH 7 0.49 4.55 1.6 14.88
51 INT21940 Positive_regulation of CALR 15 0.40 17.42 0.95 11.76
52 INT44378 Gene_expression of GSTM1 69 0.76 34.61 8.81 10.72
53 INT188776 Positive_regulation of IFIH1 10 0.23 9.93 0.35 9.04
54 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
55 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
56 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
57 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
58 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
59 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
60 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 5.00
61 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
62 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 5.00
63 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 5.00
64 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 5.00
65 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
66 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 5.00
67 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
68 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 5.00
69 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 5.00
70 INT192409 Positive_regulation of Gene_expression of IFN1@ 102 0.67 64.66 18.8 5.00
71 INT75540 Positive_regulation of TH1L 62 0.67 43.45 15.02 5.00
72 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 5.00
73 INT3623 Negative_regulation of CTSB 49 0.55 27.39 13.52 5.00
74 INT58904 Localization of TH1L 40 0.68 27.11 10.52 5.00
75 INT32344 Localization of LTF 30 0.80 15.28 10.09 5.00
76 INT3622 Regulation of CTSB 34 0.58 16.08 8.76 5.00
77 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57 5.00
78 INT182898 Regulation of Gene_expression of IFN1@ 18 0.44 9.49 4.46 5.00
79 INT22009 Negative_regulation of Ctsa 12 0.58 3.14 3.59 5.00
80 INT176386 Positive_regulation of Gene_expression of TH1L 14 0.32 9.17 3.4 5.00
81 INT192676 Binding of PTEN 14 0.46 10.58 3.06 5.00
82 INT103020 Gene_expression of SGCA 22 0.56 14.29 2.75 5.00
83 INT110980 Gene_expression of CTSB 17 0.45 8.02 2.69 5.00
84 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5 5.00
85 INT152223 Binding of BEST1 10 0.29 6.67 1.46 5.00
86 INT27256 Localization of STH 6 0.70 0.46 1.29 5.00
87 INT23518 Gene_expression of Ctsa 6 0.32 1.11 1.16 5.00
88 INT118217 Regulation of Cuzd1 2 0.30 2.36 0.91 5.00
89 INT297919 Negative_regulation of Gene_expression of LTF 2 0.09 3.27 0.79 5.00
90 INT200855 Positive_regulation of Kdr 14 0.45 11.14 0.77 5.00
91 INT208142 Gene_expression of PITX1 3 0.65 9.36 0.73 5.00
92 INT67389 Positive_regulation of SGCA 7 0.45 2.92 0.69 5.00
93 INT241797 Gene_expression of CHIT1 10 0.24 9.75 0.69 5.00
94 INT44478 Negative_regulation of PTEN 32 0.57 27.45 0.63 5.00
95 INT188775 Binding of IFIH1 11 0.16 12.4 0.61 5.00
96 INT182806 Binding of Cuzd1 3 0.24 1.45 0.53 5.00
97 INT59793 Regulation of Gene_expression of STH 2 0.44 0.88 0.51 5.00
98 INT68907 Regulation of AICDA 4 0.44 0.77 0.47 5.00
99 INT188173 Gene_expression of CDH5 14 0.49 3.17 0.44 5.00
100 INT189176 Positive_regulation of Localization of TH1L 5 0.23 2.93 0.42 5.00
101 INT191731 Gene_expression of Lmrq1 31 0.43 14.46 0.34 5.00
102 INT152643 Positive_regulation of Gene_expression of IFIH1 5 0.42 5.2 0.28 5.00
103 INT196006 Regulation of FLT4 2 0.25 2.24 0.27 5.00
104 INT275900 Regulation of Localization of TH1L 2 0.26 0.99 0.26 5.00
105 INT288384 Binding of CHIT1 2 0.15 2.04 0.22 5.00
106 INT197104 Positive_regulation of Gene_expression of FLT4 1 0.56 3.45 0.19 5.00
107 INT197102 Localization of FLT4 4 0.65 2.89 0.17 5.00
108 INT179431 Localization of AICDA 9 0.78 2.34 0.16 5.00
109 INT217052 Localization of Lmrq1 6 0.44 3.36 0.15 5.00
110 INT197103 Binding of FLT4 2 0.29 3.08 0.14 5.00
111 INT208140 Localization of PITX1 2 0.73 6.18 0.14 5.00
112 INT154235 Gene_expression of KPNA1 2 0.78 1.77 0.1 5.00
113 INT182809 Negative_regulation of Binding of Cuzd1 1 0.28 0.47 0.1 5.00
114 INT196007 Positive_regulation of FLT4 2 0.56 5.44 0.08 5.00
115 INT188176 Positive_regulation of Gene_expression of CDH5 3 0.32 0.75 0.07 5.00
116 INT275899 Positive_regulation of Localization of Lmrq1 3 0.09 1.5 0.07 5.00
117 INT197101 Positive_regulation of Localization of FLT4 1 0.38 0.77 0.06 5.00
118 INT354758 Gene_expression of D6Uwa4 1 0.04 0.17 0 5.00
119 INT228359 Binding of STH 1 0.09 0.28 0 5.00
120 INT275898 Regulation of Localization of Lmrq1 1 0.07 0.48 0 5.00
121 INT189063 Regulation of NDS9 1 0.01 0.8 0 5.00
122 INT221711 Negative_regulation of Gene_expression of STH 1 0.06 0.81 0 5.00
123 INT248744 Negative_regulation of STH 2 0.41 1.02 0 5.00
124 INT202814 Binding of CEACAM5 1 0.17 1.14 0 5.00
125 INT208141 Positive_regulation of PITX1 1 0.30 1.46 0 5.00
126 INT260240 Binding of HEPH 1 0.36 0.25 0 5.00
127 INT320479 Regulation of Localization of AICDA 1 0.19 0.08 0 5.00
128 INT288383 Regulation of Gene_expression of CHIT1 1 0.18 2.99 0 5.00
129 INT228360 Positive_regulation of Gene_expression of STH 1 0.10 0.52 0 5.00
130 INT178835 Negative_regulation of Binding of Dync1h1 2 0.36 0.85 0 5.00
131 INT260239 Localization of HEPH 1 0.78 0.48 0 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox