D:Open Fractures

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pChart

Disease Term
Synonyms Compound Fracture, Compound Fractures, Fracture Compound, Fracture Open, FRACTURES COMPOUND, Open Fracture
Documents 218
Hot Single Events 6
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Open Fractures. They are ordered first by their relevance to Open Fractures and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT278021 BMP2 Positive_regulation of Gene_expression of RUNX1T1 1 0.02 0.5 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Open Fractures. They are ordered first by their pain relevance and then by number of times they were reported in Open Fractures. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT199004 Gene_expression of ARMC9 43 0.58 17.72 1.32 99.84
2 INT105466 Binding of HM13 1 0.36 1.13 0.09 98.84
3 INT128699 Regulation of Il12a 3 0.45 3.36 1.59 98.12
4 INT199005 Localization of KRT2 1 0.05 1.5 0 96.08
5 INT156544 Regulation of Il12b 2 0.44 1.29 0.66 95.32
6 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82 93.32
7 INT85878 Negative_regulation of Il12a 4 0.58 2.88 2.21 73.68
8 INT105021 Binding of GOPC 187 0.40 60.39 20.38 71.56
9 INT3364 Binding of SGCG 87 0.47 31.93 17.24 67.56
10 INT169590 Localization of FES 1 0.65 1.56 0.27 64.08
11 INT169592 Localization of FAT1 3 0.51 3.21 0.91 60.80
12 INT96499 Gene_expression of FES 5 0.65 2.26 0.48 53.64
13 INT169591 Gene_expression of FAT1 23 0.67 10.73 0.77 51.12
14 INT304488 Binding of KLHDC2 1 0.04 0 0.08 37.16
15 INT70265 Regulation of MRI1 42 0.39 30.95 14.18 33.96
16 INT130014 Positive_regulation of BMP2 11 0.66 5.34 1.42 29.44
17 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
18 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
19 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97 5.00
20 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 5.00
21 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63 5.00
22 INT2792 Gene_expression of Mb 91 0.76 41.56 10.25 5.00
23 INT127203 Positive_regulation of Mcf2l 14 0.43 9.84 7.03 5.00
24 INT12104 Positive_regulation of PLG 45 0.68 28.94 4.81 5.00
25 INT11635 Positive_regulation of Gene_expression of SERPINE1 35 0.68 24.57 4.26 5.00
26 INT149259 Gene_expression of RCT 38 0.67 15.73 3.87 5.00
27 INT85809 Gene_expression of BMP2 46 0.78 9.91 3.05 5.00
28 INT110210 Negative_regulation of CSRP1 12 0.59 8.96 2.81 5.00
29 INT15654 Gene_expression of Tg 22 0.66 12.2 2.36 5.00
30 INT81982 Gene_expression of Bmpr2 36 0.60 14.58 1.55 5.00
31 INT211969 Positive_regulation of Best1 34 0.11 14.92 1.44 5.00
32 INT32118 Regulation of Mcf2l 6 0.39 3.05 1.34 5.00
33 INT29788 Gene_expression of DNASE1L1 3 0.03 0.61 0.99 5.00
34 INT153329 Gene_expression of Cm9 6 0.67 4.35 0.95 5.00
35 INT114664 Binding of BMP2 12 0.37 6.54 0.91 5.00
36 INT171096 Transcription of PDGFA 5 0.47 4.42 0.79 5.00
37 INT151217 Phosphorylation of SIGMAR1 2 0.04 0.41 0.72 5.00
38 INT139205 Binding of NRP1 27 0.45 4.34 0.71 5.00
39 INT67988 Positive_regulation of ROM1 7 0.41 1.9 0.7 5.00
40 INT85808 Localization of BMP2 7 0.77 1.94 0.51 5.00
41 INT201967 Positive_regulation of Bmpr2 4 0.31 1.24 0.34 5.00
42 INT251324 Binding of Bmpr2 5 0.23 2.99 0.34 5.00
43 INT211971 Binding of Best1 16 0.22 7.73 0.33 5.00
44 INT87963 Regulation of Tg 3 0.45 2.7 0.32 5.00
45 INT109699 Regulation of BMP2 5 0.43 2.21 0.23 5.00
46 INT220839 Gene_expression of Cd244 7 0.29 3.2 0.19 5.00
47 INT322091 Negative_regulation of Cd244 1 0.18 0.49 0.16 5.00
48 INT278037 Positive_regulation of Transcription of PDGFA 4 0.07 2.39 0.12 5.00
49 INT39866 Gene_expression of RUNX1T1 2 0.65 1.75 0.1 5.00
50 INT278036 Negative_regulation of BMP2 2 0.34 0.64 0.09 5.00
51 INT201962 Transcription of Bmpr2 6 0.37 3.51 0.09 5.00
52 INT254332 Negative_regulation of Gene_expression of Bmpr2 3 0.22 2.41 0.07 5.00
53 INT322090 Positive_regulation of Cd244 1 0.20 0.49 0.04 5.00
54 INT278039 Phosphorylation of BMPR2 1 0.08 0.26 0.03 5.00
55 INT225689 Gene_expression of SMS 10 0.65 5.66 0.03 5.00
56 INT278034 Transcription of BMP1 1 0.07 0.25 0.03 5.00
57 INT278022 Phosphorylation of Bmpr2 1 0.21 0.27 0.03 5.00
58 INT304489 Localization of KLHDC2 1 0.09 0.08 0 5.00
59 INT270301 Negative_regulation of DIP 1 0.01 0.23 0 5.00
60 INT278035 Positive_regulation of Gene_expression of DNASE1L1 1 0.01 0.38 0 5.00
61 INT219929 Positive_regulation of Gene_expression of Bmpr2 3 0.15 0.9 0 5.00
62 INT278040 Negative_regulation of Localization of BMP2 1 0.32 0.32 0 5.00
63 INT79726 Binding of Spef1 2 0.05 0.44 0 5.00
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