D:Optic Neuritis

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pChart

Disease Term
Synonyms ANTERIOR OPTIC NEURITIDES, Anterior Optic Neuritis, Neuritides Anterior Optic, Neuritides Optic, Neuritides Posterior Optic, Neuritides Retrobulbar, Neuritis Anterior Optic, Neuritis Optic, NEURITIS POSTERIOR OPTIC, NEURITIS RETROBULBAR, Neuropapillitides
Documents 3055
Hot Single Events 200
Hot Interactions 36

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Optic Neuritis. They are ordered first by their relevance to Optic Neuritis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT154778 Cldn11 Positive_regulation of Eae1 4 0.12 3.24 1.03 99.88
2 INT45496 Binding of CSF2 and C6orf25 1 0.03 1.08 0.59 98.56
3 INT169648 IGHG3 Regulation of AQP4 3 0.02 4.63 0.55 97.56
4 INT122567 Mog Positive_regulation of Eae1 8 0.31 10.18 4.26 97.54
5 INT308708 DDX41 Regulation of AQP4 1 0.10 2.79 0.26 96.76
6 INT161166 Binding of Aqp4 and Igh-6 1 0.03 2.58 0.49 96.00
7 INT36999 Binding of HLA-DRB2 and TNFRSF25 1 0.05 3.46 0.91 95.44
8 INT140386 Spp1 Positive_regulation of NFKB1 1 0.21 1.29 0.3 94.52
9 INT140385 Spp1 Negative_regulation of FOXO3 1 0.04 1.29 0.3 94.52
10 INT235956 Binding of Aqp4 and NMO-IgG 1 0.04 4.53 0.5 94.08
11 INT235958 Binding of Ighg1 and Aqp4 1 0.14 1.32 0.3 94.08
12 INT235975 Binding of AQP4 and IgG 2 0.04 4.11 0.53 93.84
13 INT235977 Binding of AQP4 and Ighg1 1 0.03 1.31 0.3 93.84
14 INT308701 Binding of AQP4 and DDX41 1 0.15 3.53 0.32 93.00
15 INT308709 Positive_regulation of Binding of AQP4 and DDX41 1 0.18 1.19 0.14 93.00
16 INT139683 Binding of Cldn11 and 2410016O06Rik 1 0.02 1.06 0.4 92.08
17 INT339967 Binding of Mog and Eae1 1 0.02 1.67 0.6 91.68
18 INT139684 Binding of Cd4 and 2410016O06Rik 1 0.02 1.05 0.4 91.48
19 INT169101 Binding of HLA-A and HLA-DRB1 1 0.24 1.09 0.63 91.48
20 INT181437 Binding of Ccr7 and Ccl21b 1 0.01 2.23 0.87 90.04
21 INT181452 Binding of Ccl19 and Ccl21b 1 0.02 2.22 0.86 89.64
22 INT48304 Positive_regulation of MBP Positive_regulation of PLP1 1 0.10 0.97 0.64 88.64
23 INT48303 MBP Positive_regulation of PLP1 1 0.10 0.97 0.64 88.24
24 INT96590 Mog Regulation of S100B 1 0.32 0.97 0.13 87.40
25 INT96589 Mbp Regulation of S100B 1 0.34 0.97 0.13 87.40
26 INT334153 Binding of AQP4 and CSF2 1 0.16 3 0.75 87.16
27 INT247851 Negative_regulation of Aqp4 Negative_regulation of Positive_regulation of Narfl 1 0.09 1.78 0.15 86.24
28 INT206763 Binding of CSF2 and Nqo1 1 0.00 1.7 0.25 85.04
29 INT128944 Binding of Mbp and Mog 1 0.08 0.8 0.43 84.80
30 INT241910 Binding of Alb and Alms1 1 0.02 0.52 0.13 84.56
31 INT128945 Binding of MBP and Mog 1 0.01 1.59 0.86 84.40
32 INT241912 Cat Positive_regulation of Ros1 1 0.03 0.76 0.44 83.60
33 INT241914 SOD1 Positive_regulation of Ros1 1 0.00 0.76 0.44 83.08
34 INT206764 Binding of AQP4 and Nqo1 8 0.05 13.45 2.84 81.76
35 INT121963 Itpka Negative_regulation of Positive_regulation of Phospho1 1 0.01 0.59 0.22 80.48
36 INT307663 Binding of Pmp22 and Egr2 1 0.33 0.39 0.08 80.32
37 INT307664 Binding of Pmp22 and LOC689781 1 0.03 0.39 0.08 79.60
38 INT307665 Binding of Mpz and Pmp22 1 0.34 0.39 0.08 78.96
39 INT241911 Binding of Cat and Ros1 1 0.03 0.85 0.27 78.88
40 INT307666 Binding of Pmp22 and Gjb1 1 0.31 0.38 0.08 78.56
41 INT126555 Binding of Ighg1 and Tnf 1 0.35 2.2 0.8 75.00
42 INT62055 Mbp Positive_regulation of Lta 1 0.07 1.4 0.51 75.00
43 INT332581 Binding of Nqo1 and MRI1 1 0.01 1.68 0.12 73.36
44 INT235974 Negative_regulation of Binding of APC and Trav6-3 1 0.00 1.15 0.24 72.80
45 INT235972 Negative_regulation of Binding of APC and Bcr 1 0.01 1.15 0.24 72.80
46 INT235976 Binding of APC and Trav6-3 2 0.01 2.62 0.24 72.24
47 INT235973 Binding of APC and Bcr 1 0.01 1.14 0.24 71.92
48 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78 71.84
49 INT157343 Binding of AQP4 and HLA-DPB1 1 0.30 0.89 0.43 70.32
50 INT241913 AAVS1 Positive_regulation of Cat 1 0.04 0.46 0.1 66.92
51 INT154780 Positive_regulation of Eae1 Negative_regulation of Cldn11 Positive_regulation of Eae1 1 0.03 0.72 0.18 66.84
52 INT154779 Eae1 Negative_regulation of Cldn11 Positive_regulation of Eae1 1 0.03 0.72 0.18 66.84
53 INT235957 Binding of Mog and Bcr 1 0.02 1.13 0.29 58.40
54 INT235962 Binding of Bcr and Trav6-3 1 0.00 1.12 0.29 58.40
55 INT235966 Binding of Mog and Trav6-3 1 0.01 1.07 0.29 58.00
56 INT353230 MOG Positive_regulation of Eae1 1 0.07 1.09 0.1 57.12
57 INT328667 Binding of CD40LG and CSF2 1 0.16 0.59 0.05 54.48
58 INT328668 Binding of CSF2 and IGHG3 1 0.03 0.59 0.05 54.48
59 INT235971 Positive_regulation of Binding of Nqo1 and NMO-IgG 1 0.00 1.86 0.32 51.76
60 INT140172 Binding of Nqo1 and IgG 5 0.17 6.68 1.2 51.40
61 INT181432 Csf2 Positive_regulation of Ccl5 1 0.03 0.81 0.29 43.24
62 INT181446 Csf2 Positive_regulation of Ccl3 1 0.05 0.81 0.29 43.24
63 INT308704 Binding of DDX41 and M1 1 0.02 2.09 0.1 34.48
64 INT256165 Binding of Sirt6 and Sirt1 1 0.13 0.58 0 32.00
65 INT274449 Binding of Cd4 and H2 2 0.05 1.25 0.1 29.24
66 INT337072 Binding of Fmr1 and Gusb 1 0.19 1.55 0.08 29.04
67 INT308702 Binding of AQP4 and CD40LG 1 0.10 0 0 28.44
68 INT152049 Scd1 Negative_regulation of Trav6-3 1 0.00 0.19 0 25.00
69 INT181442 Ccl2 Positive_regulation of Localization of Hand2 1 0.26 0.63 0.29 23.84
70 INT247843 Narfl Regulation of Aqp4 1 0.04 1.07 0.04 22.40
71 INT247855 Positive_regulation of Narfl Regulation of Aqp4 1 0.04 2.93 0.04 22.40
72 INT181438 Il4 Regulation of Gene_expression of Ccl2 1 0.38 0.74 0.35 22.12
73 INT181433 Hand2 Regulation of Gene_expression of Ccl2 1 0.12 0.68 0.32 22.12
74 INT235967 Binding of Ighm and Nqo1 1 0.00 1.45 0.23 21.08
75 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
76 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
77 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66 5.00
78 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09 5.00
79 INT306745 Binding of Il12a and IL23A 1 0.10 3.25 1.56 5.00
80 INT181436 Binding of Ccl2 and Eae1 1 0.05 5.14 1.27 5.00
81 INT119108 Binding of LTBR and TNF 2 0.15 1.47 1.07 5.00
82 INT181434 Binding of Ccr2 and Ccl2 1 0.27 6.06 1.04 5.00
83 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03 5.00
84 INT231533 IL4 Positive_regulation of LRP5 1 0.00 0.87 0.67 5.00
85 INT231534 Binding of JAK1 and SOAT1 1 0.01 0.6 0.64 5.00
86 INT172081 TNF Regulation of IFNA1 1 0.03 1.13 0.5 5.00
87 INT172082 TNF Regulation of SFTPA1 1 0.05 0.85 0.5 5.00
88 INT306732 Il17a Positive_regulation of Gene_expression of Il2 1 0.09 1.07 0.46 5.00
89 INT306731 Il22 Positive_regulation of Gene_expression of Il2 1 0.12 1.07 0.46 5.00
90 INT181444 Ccl5 Positive_regulation of Csf2 1 0.07 1.88 0.45 5.00
91 INT307781 Apoa1 Positive_regulation of LCAT 1 0.76 1.19 0.45 5.00
92 INT181447 Ccl3 Positive_regulation of Csf2 1 0.06 1.89 0.45 5.00
93 INT307780 Apoa1 Positive_regulation of Soat1 1 0.04 1.14 0.42 5.00
94 INT181448 Eae1 Positive_regulation of Gene_expression of Ccr2 1 0.04 4.98 0.42 5.00
95 INT211115 Positive_regulation of Binding of LTBR and TNF 1 0.01 0.31 0.39 5.00
96 INT181443 Csf2 Positive_regulation of Cxcl10 1 0.02 1.69 0.39 5.00
97 INT237778 Il12b Positive_regulation of Gene_expression of Eae1 1 0.01 1.51 0.39 5.00
98 INT181441 Csf2 Positive_regulation of Cxcl12 1 0.02 1.69 0.39 5.00
99 INT181439 Csf2 Positive_regulation of Ccl19 1 0.06 1.68 0.38 5.00
100 INT353454 Binding of BRCA1 and IL17A 1 0.00 2.55 0.36 5.00
101 INT231535 Binding of JAK2 and SOAT1 1 0.01 0.3 0.35 5.00
102 INT181453 Gene_expression of Ccl2 Positive_regulation of Gene_expression of Il12rb1 1 0.06 1.87 0.34 5.00
103 INT353452 Binding of AGRP and BRCA1 1 0.00 3.89 0.34 5.00
104 INT181451 Lck Regulation of Mbp 1 0.08 1.43 0.34 5.00
105 INT181435 Binding of Ccr2 and Hand2 1 0.17 1.81 0.32 5.00
106 INT353448 BRCA1 Positive_regulation of CCL2 1 0.01 1.37 0.26 5.00
107 INT353449 BRCA1 Positive_regulation of IL4 1 0.00 1.37 0.26 5.00
108 INT353455 BRCA1 Positive_regulation of IL13 1 0.00 1.37 0.26 5.00
109 INT235959 Nqo1 Positive_regulation of Localization of Aqp4 1 0.02 1.39 0.26 5.00
110 INT181454 Eae7 Regulation of Positive_regulation of Eae1 1 0.06 0.9 0.26 5.00
111 INT181449 Ccl7 Regulation of Ccl2 1 0.24 0.73 0.25 5.00
112 INT279961 CSF2 Negative_regulation of TTR 1 0.04 1.07 0.23 5.00
113 INT181445 Binding of Ccr5 and Hand1 1 0.12 1.01 0.22 5.00
114 INT172083 TNF Regulation of Regulation of IFNA1 1 0.03 0.91 0.22 5.00
115 INT260870 Binding of HLA-E and IL7R 1 0.19 0.5 0.22 5.00
116 INT241822 Binding of CD4 and HIVEP1 3 0.01 2.73 0.21 5.00
117 INT306714 IL23A Positive_regulation of TNF 1 0.29 0.5 0.21 5.00
118 INT306746 Il12a Positive_regulation of TNF 1 0.24 0.5 0.21 5.00
119 INT279964 STAT3 Regulation of Transcription of FGG 1 0.22 1.37 0.2 5.00
120 INT306744 IL23A Positive_regulation of Il12a 1 0.13 0.59 0.2 5.00
121 INT181440 Binding of Ccr2 and Eae1 1 0.03 1.3 0.19 5.00
122 INT237777 Il23a Regulation of Localization of Il12a 1 0.19 0.93 0.19 5.00
123 INT279965 STAT3 Regulation of Transcription of BCL2L1 1 0.10 2.31 0.19 5.00
124 INT274386 Binding of CD4 and ERVW-1 1 0.05 3.07 0.18 5.00
125 INT181457 Binding of CCL16 and Hand2 1 0.04 0.92 0.17 5.00
126 INT327789 Binding of IgG and Alms1 1 0.01 1.1 0.17 5.00
127 INT327790 Binding of Nqo1 and Alms1 1 0.00 1.1 0.17 5.00
128 INT327791 Binding of AQP4 and Alms1 1 0.03 1.1 0.17 5.00
129 INT321957 Binding of Sar1a and Ceacam1 1 0.01 0.96 0.16 5.00
130 INT306747 IL23A Positive_regulation of Il17a 1 0.05 0.51 0.16 5.00
131 INT314856 Binding of Cdc7 and Cdkn2a 1 0.28 1.34 0.14 5.00
132 INT259023 CADPS Positive_regulation of Binding of SH2B2 1 0.06 2.05 0.14 5.00
133 INT353451 Binding of BRCA1 and CRP 1 0.01 1.18 0.14 5.00
134 INT314867 Binding of Cdc7 and Cdkn2b 1 0.25 1.16 0.14 5.00
135 INT314852 Binding of Cdkn2a and Tgfbr3 1 0.28 1.15 0.14 5.00
136 INT235961 Binding of Nqo1 and Aqp4 1 0.02 0.9 0.14 5.00
137 INT353453 Binding of BRCA1 and IL4 1 0.00 1.18 0.14 5.00
138 INT314859 Binding of Cdkn2b and Tgfbr3 1 0.33 1.16 0.14 5.00
139 INT237774 Il12b Positive_regulation of Eae1 1 0.01 0.58 0.13 5.00
140 INT327792 Binding of IGFALS and Alms1 1 0.00 1.15 0.11 5.00
141 INT279962 Binding of A1BG and BCL2L1 1 0.13 1.11 0.1 5.00
142 INT308749 Gene_expression of C11orf9 Positive_regulation of Gene_expression of MAG 1 0.13 0.08 0.09 5.00
143 INT237776 Ifna1 Positive_regulation of Eae1 1 0.07 0.66 0.09 5.00
144 INT235964 Binding of Atp9a and Aqp4 1 0.01 0.55 0.08 5.00
145 INT256160 Positive_regulation of Binding of Pgc and Sirt1 1 0.55 0.21 0.07 5.00
146 INT256161 Binding of Pgc and Sirt1 1 0.38 0.21 0.07 5.00
147 INT193564 Binding of STMN1 and MRI1 1 0.07 0.06 0.07 5.00
148 INT332588 Binding of RAPH1 and MND1 1 0.01 3.88 0.07 5.00
149 INT334683 Eae1 Regulation of Cnp 1 0.03 0.5 0.06 5.00
150 INT334687 Eae1 Regulation of Gene_expression of Cnp 1 0.06 0.5 0.06 5.00
151 INT334686 Olig1 Regulation of Plp1 1 0.17 0.55 0.06 5.00
152 INT334689 Olig1 Regulation of Gene_expression of Cnp 1 0.20 0.55 0.06 5.00
153 INT334684 Eae1 Regulation of Plp1 1 0.05 0.5 0.06 5.00
154 INT334682 Olig1 Regulation of Cnp 1 0.09 0.55 0.06 5.00
155 INT334685 Olig1 Regulation of Gene_expression of Plp1 1 0.17 0.55 0.06 5.00
156 INT334688 Eae1 Regulation of Gene_expression of Plp1 1 0.05 0.5 0.06 5.00
157 INT353450 Binding of BRCA1 and VEGFA 1 0.01 0.82 0.05 5.00
158 INT235963 Snta1 Regulation of Gene_expression of Aqp4 1 0.41 0.23 0.05 5.00
159 INT329015 Binding of APCS and SRGN 1 0.08 1.14 0.04 5.00
160 INT235969 Binding of Ighg1 and Nqo1 1 0.01 2.63 0.04 5.00
161 INT233397 Binding of ABCA4 and COL2A1 1 0.38 3.59 0.03 5.00
162 INT235968 NMO-IgG Positive_regulation of Nqo1 1 0.00 2.11 0.03 5.00
163 INT332587 MND1 Positive_regulation of Binding of RAPH1 and MND1 1 0.00 2.21 0.03 5.00
164 INT247856 Narfl Negative_regulation of Gene_expression of Uchl1 1 0.03 1 0.03 5.00
165 INT308748 TPPP Regulation of MIR1-1 1 0.04 0.13 0.03 5.00
166 INT274384 AGRP Negative_regulation of HIVEP1 1 0.00 0.77 0.03 5.00
167 INT308750 Binding of BCL2L1 and MIR184 1 0.13 0.11 0.03 5.00
168 INT314869 Binding of Gdf11 and Tgfbr3 1 0.29 0.14 0 5.00
169 INT200761 Binding of Tfam and Gopc 1 0.01 0.1 0 5.00
170 INT321958 Binding of Vtn and Ceacam1 1 0.02 0.27 0 5.00
171 INT247847 Narfl Positive_regulation of Positive_regulation of Casp3 1 0.02 0.79 0 5.00
172 INT247853 Positive_regulation of Narfl Negative_regulation of Gene_expression of Uchl1 1 0.03 0.54 0 5.00
173 INT247846 Positive_regulation of Narfl Positive_regulation of Positive_regulation of Ube4a 1 0.00 0.82 0 5.00
174 INT314865 Binding of Ltbp3 and Tgfb1 1 0.24 0.51 0 5.00
175 INT314863 Binding of Neurod1 and Atoh7 1 0.18 0.27 0 5.00
176 INT314850 Shh Regulation of Atoh7 1 0.45 0.22 0 5.00
177 INT314858 Binding of Gdf11 and Ltbp3 1 0.39 0.31 0 5.00
178 INT314854 Gdf11 Regulation of Atoh7 1 0.51 0.21 0 5.00
179 INT314871 Binding of Tgfbr3 and Atoh7 1 0.33 0.09 0 5.00
180 INT298688 Binding of OPA1 and MFN1 1 0.52 2.09 0 5.00
181 INT314855 Binding of Gdf11 and Atoh7 1 0.40 0.14 0 5.00
182 INT347723 Binding of Aqp4 and Tmed4 1 0.27 0 0 5.00
183 INT314862 Binding of Ltbp3 and Tgfb2 1 0.24 0.52 0 5.00
184 INT298687 Binding of OPA1 and PARL 1 0.50 2.09 0 5.00
185 INT308706 Binding of AQP4 and M1 1 0.06 0.86 0 5.00
186 INT314868 Binding of Ltbp2 and Ltbp3 1 0.29 0.54 0 5.00
187 INT247848 Narfl Negative_regulation of Uchl1 1 0.03 0.74 0 5.00
188 INT308703 Positive_regulation of Binding of AQP4 and M1 1 0.08 0.61 0 5.00
189 INT314851 Positive_regulation of Binding of Neurod1 and Atoh7 1 0.23 0.27 0 5.00
190 INT308707 Binding of AQP4 and IGHG3 1 0.01 0.88 0 5.00
191 INT314866 Binding of Six1 and Sall1 1 0.39 0.76 0 5.00
192 INT314870 Binding of Ltbp3 and Tgfb3 1 0.24 0.52 0 5.00
193 INT331563 Binding of Cd4 and Apcs 1 0.17 0.36 0 5.00
194 INT314861 Gdf11 Regulation of Gene_expression of Atoh7 1 0.20 0.26 0 5.00
195 INT247857 Narfl Positive_regulation of Gene_expression of Gfap 1 0.07 0.81 0 5.00
196 INT274385 Binding of ABAT and CDIPT 1 0.00 1.21 0 5.00
197 INT265383 Hsp90aa1 Negative_regulation of HDAC9 1 0.06 0.7 0 5.00
198 INT247888 Narfl Positive_regulation of CASP3 1 0.00 0.77 0 5.00
199 INT247850 Positive_regulation of Narfl Regulation of Ube4a 1 0.00 1.86 0 5.00
200 INT314857 Atoh7 Regulation of Pou4f2 1 0.21 0.21 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Optic Neuritis. They are ordered first by their pain relevance and then by number of times they were reported in Optic Neuritis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT335959 Negative_regulation of Positive_regulation of Ubl4 1 0.27 4.53 3.05 100.00
2 INT335958 Negative_regulation of Binding of Ubl4 1 0.27 2.08 1.34 100.00
3 INT335955 Negative_regulation of Ubl4 1 0.27 2.28 1.53 100.00
4 INT141656 Regulation of Eae1 22 0.39 32.62 8.12 100.00
5 INT120067 Positive_regulation of Gene_expression of CCR2 10 0.46 5.13 3.02 100.00
6 INT25362 Binding of NFKBIA 4 0.26 2.52 0.55 100.00
7 INT167520 Binding of Ubl4 2 0.29 3.93 2.66 99.98
8 INT112372 Positive_regulation of GPSM2 8 0.41 5.49 1.94 99.96
9 INT87393 Gene_expression of Ccr5 19 0.65 11 10.51 99.96
10 INT112373 Negative_regulation of Positive_regulation of GPSM2 1 0.38 1.87 0.73 99.96
11 INT103847 Positive_regulation of Ccr5 11 0.55 6.04 5.79 99.96
12 INT58458 Positive_regulation of Mog 4 0.50 5.79 2.37 99.96
13 INT103843 Positive_regulation of Gene_expression of Ccr5 5 0.42 2.31 3.89 99.96
14 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 99.96
15 INT56299 Transcription of IL4 15 0.64 10.2 5.44 99.96
16 INT4929 Binding of Mbp 25 0.48 18.01 9.41 99.92
17 INT116398 Gene_expression of Mog 25 0.77 23.11 6.33 99.92
18 INT99505 Gene_expression of Bcl2l1 42 0.77 33.12 10.15 99.92
19 INT116614 Positive_regulation of Gene_expression of Bcl2l1 12 0.67 11.39 4.68 99.92
20 INT541 Positive_regulation of MBP 31 0.67 28.56 12.24 99.90
21 INT8518 Localization of Ifng 53 0.81 36.68 24.13 99.90
22 INT7580 Positive_regulation of Mbp 54 0.70 23.37 17.14 99.90
23 INT137767 Gene_expression of Eae1 74 0.34 89.32 20.48 99.90
24 INT44320 Positive_regulation of Cldn11 5 0.39 2.95 1.81 99.88
25 INT109558 Binding of Eae1 9 0.25 10.36 3.16 99.88
26 INT84981 Negative_regulation of Gene_expression of CAT 3 0.41 0.35 0.35 99.88
27 INT14887 Gene_expression of Mbp 55 0.75 36.13 16.11 99.84
28 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 99.84
29 INT54720 Positive_regulation of HLA-DRB5 9 0.34 6.7 2.51 99.84
30 INT19331 Positive_regulation of HLA-A 12 0.49 7.72 3.28 99.84
31 INT113985 Positive_regulation of TP63 9 0.50 8.79 1.62 99.84
32 INT62430 Negative_regulation of HLA-A 5 0.32 4.3 1.63 99.84
33 INT637 Positive_regulation of MRAP 23 0.67 21.13 9.97 99.84
34 INT123907 Negative_regulation of IGKV6-21 1 0.25 1.14 0.94 99.84
35 INT103845 Gene_expression of Cxcr3 13 0.60 10.65 8.5 99.78
36 INT103848 Positive_regulation of Cxcr3 4 0.54 3.12 2.88 99.78
37 INT103849 Positive_regulation of Gene_expression of Cxcr3 4 0.40 1.9 1.44 99.78
38 INT164116 Negative_regulation of 1190002H23Rik 33 0.51 18.73 2.71 99.68
39 INT164113 Negative_regulation of Negative_regulation of 1190002H23Rik 10 0.51 3.98 0.62 99.68
40 INT8466 Binding of Plp1 5 0.48 5.07 2.29 99.66
41 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 99.66
42 INT81493 Transcription of CCL2 20 0.65 13.63 6.78 99.66
43 INT235938 Binding of Mog 3 0.34 9.61 3.09 99.64
44 INT335956 Positive_regulation of Ubl4 1 0.32 2.24 1.51 99.64
45 INT84703 Negative_regulation of Nqo1 8 0.38 7.1 4.05 99.54
46 INT334680 Negative_regulation of Olig1 1 0.43 9.5 2.32 99.52
47 INT7678 Localization of Alb 142 0.81 80.93 22.49 99.52
48 INT108484 Gene_expression of CCL19 4 0.50 12.56 3.63 99.48
49 INT1672 Gene_expression of Mtr 18 0.67 3.39 13.32 99.44
50 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 99.44
51 INT2836 Positive_regulation of PAEP 51 0.67 26.69 4.57 99.42
52 INT14486 Localization of Mbp 23 0.74 11.24 6.14 99.40
53 INT77809 Gene_expression of NUP214 3 0.65 1.35 1.24 99.40
54 INT108481 Positive_regulation of CCL19 4 0.44 15.22 3.77 99.36
55 INT108479 Positive_regulation of CCL21 18 0.67 19.93 10.76 99.36
56 INT108483 Positive_regulation of Gene_expression of CCL21 7 0.69 5.76 2.45 99.36
57 INT108486 Positive_regulation of Gene_expression of CCL19 2 0.45 6.2 1.79 99.36
58 INT140411 Gene_expression of Nqo1 45 0.60 62.35 8.7 99.32
59 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 99.28
60 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 99.28
61 INT95500 Positive_regulation of Nefh 14 0.50 4.45 12.26 99.28
62 INT152048 Negative_regulation of Gene_expression of Trav6-3 4 0.57 1.47 0.1 99.28
63 INT119671 Gene_expression of IBSP 10 0.58 4.31 1.26 99.24
64 INT101013 Regulation of HLA-A 7 0.33 6.7 1.8 99.24
65 INT140170 Binding of Nqo1 24 0.38 36.16 6.79 99.20
66 INT12250 Negative_regulation of Mtr 19 0.50 6.9 5.35 99.12
67 INT95414 Positive_regulation of Alms1 40 0.41 20.3 8.1 99.12
68 INT235929 Regulation of Positive_regulation of Alms1 2 0.02 2.84 1.02 99.12
69 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 99.06
70 INT50212 Gene_expression of Ifx 33 0.75 32.17 7.26 99.06
71 INT215923 Positive_regulation of Mog 8 0.19 9.86 3.17 99.04
72 INT48307 Positive_regulation of PLP1 5 0.66 8.42 5.09 98.96
73 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07 98.96
74 INT184723 Positive_regulation of Sod3 7 0.63 7.77 1.78 98.96
75 INT62429 Binding of HCG15 1 0.01 1.59 1.04 98.94
76 INT11807 Gene_expression of Il2 266 0.78 112 64.97 98.94
77 INT36177 Binding of Alms1 70 0.31 35.47 13.81 98.90
78 INT164480 Negative_regulation of Gene_expression of Aqp4 14 0.58 10.84 1.52 98.88
79 INT108480 Gene_expression of CCL21 53 0.77 37.87 14.42 98.84
80 INT115594 Gene_expression of Cd80 9 0.67 7.8 5.92 98.84
81 INT95492 Gene_expression of Nefh 20 0.67 12.68 10.46 98.76
82 INT70145 Gene_expression of Trav6-3 136 0.76 69.6 18.05 98.76
83 INT19330 Binding of HLA-A 99 0.48 76.26 22.85 98.76
84 INT10847 Gene_expression of LAMC2 39 0.75 27 12.09 98.76
85 INT78515 Negative_regulation of Mag 10 0.54 9.4 5.06 98.72
86 INT78516 Positive_regulation of Mag 4 0.43 3.56 3.12 98.72
87 INT130837 Gene_expression of Aqp4 205 0.78 151.23 29.63 98.64
88 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72 98.64
89 INT10187 Gene_expression of Il2ra 91 0.78 52.67 16.66 98.60
90 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 98.60
91 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 98.60
92 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 98.60
93 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96 98.60
94 INT10189 Negative_regulation of Gene_expression of Il2ra 8 0.32 8.05 2.91 98.60
95 INT28617 Negative_regulation of ITPA 7 0.45 1.27 1.65 98.60
96 INT48893 Positive_regulation of Transcription of Il10 3 0.69 4.29 3.29 98.58
97 INT140413 Gene_expression of AQP4 113 0.78 139.25 25.53 98.56
98 INT536 Binding of MBP 17 0.48 6.52 3.56 98.54
99 INT78514 Gene_expression of Cast 6 0.64 4.48 3.69 98.52
100 INT11161 Gene_expression of HLA-DRB1 121 0.78 75.33 20.96 98.52
101 INT83896 Gene_expression of CD1A 19 0.68 15.58 2.1 98.48
102 INT168188 Gene_expression of PLXNA2 13 0.58 9 2.73 98.44
103 INT119669 Gene_expression of Igh-VS107 9 0.49 3.95 1.31 98.44
104 INT48892 Transcription of Il10 31 0.71 27.26 16.77 98.42
105 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 98.40
106 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42 98.40
107 INT7995 Positive_regulation of Lta 28 0.66 14.98 9.8 98.36
108 INT11696 Gene_expression of HLA-A 50 0.78 41.25 14.1 98.32
109 INT118343 Positive_regulation of Eae1 121 0.39 136.06 34.87 98.24
110 INT78517 Regulation of Gene_expression of Cast 2 0.30 1.28 1.25 98.20
111 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 98.20
112 INT17551 Positive_regulation of Gene_expression of HLA-DRA 31 0.70 15.39 6 98.16
113 INT84548 Positive_regulation of HLA-DQA1 5 0.49 1.68 1.75 98.12
114 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 98.08
115 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01 98.08
116 INT225965 Localization of Aqp4 26 0.81 18.85 3.75 98.08
117 INT48896 Positive_regulation of Gene_expression of Il10 73 0.70 43.14 35.5 98.08
118 INT206762 Gene_expression of LETM1 1 0.13 1.99 0.33 98.08
119 INT136304 Negative_regulation of Aqp4 54 0.59 48.42 7.4 98.00
120 INT334676 Regulation of Negative_regulation of Olig1 1 0.27 2.39 0.55 98.00
121 INT3151 Localization of MBP 27 0.80 7.58 2.28 97.96
122 INT123910 Gene_expression of CXCL16 5 0.49 3.81 2.82 97.96
123 INT15555 Localization of PLP1 6 0.60 3.35 2.75 97.96
124 INT98740 Regulation of Mag 2 0.24 4.53 3.42 97.96
125 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 97.92
126 INT122041 Binding of Ppara 308 0.48 189.17 51.48 97.92
127 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14 97.84
128 INT48246 Gene_expression of PLP1 18 0.64 10.33 4.73 97.80
129 INT143337 Binding of Aqp4 30 0.40 23.73 4.24 97.80
130 INT4228 Gene_expression of CAT 50 0.75 20.62 7.18 97.80
131 INT22129 Positive_regulation of Gene_expression of CAT 11 0.67 4.23 2.37 97.80
132 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 97.80
133 INT138977 Negative_regulation of Positive_regulation of 3110062M04Rik 1 0.41 0.33 0.25 97.72
134 INT131985 Positive_regulation of Il7 2 0.36 0.58 0.28 97.70
135 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 97.64
136 INT157959 Binding of AQP4 32 0.48 43.44 7.44 97.56
137 INT116622 Positive_regulation of Nefh 17 0.39 11.98 3.86 97.56
138 INT18929 Regulation of Mog 3 0.24 2.96 1.43 97.56
139 INT151373 Binding of CLDN11 1 0.36 0.84 0.29 97.52
140 INT151736 Binding of Hand1 15 0.26 9.77 4.04 97.48
141 INT156131 Binding of Hand2 14 0.25 10.35 3.99 97.48
142 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6 97.40
143 INT123909 Gene_expression of IGKV6-21 1 0.35 1.11 0.92 97.40
144 INT88098 Positive_regulation of 3110062M04Rik 10 0.48 4.37 4.45 97.40
145 INT84704 Positive_regulation of Nqo1 18 0.70 18.64 5.65 97.36
146 INT37239 Positive_regulation of Ssta2 1 0.03 1.03 0.95 97.36
147 INT7464 Regulation of Mbp 25 0.62 6.62 6.43 97.36
148 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55 97.32
149 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06 97.20
150 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 97.20
151 INT155944 Gene_expression of Foxp3 66 0.66 24.37 9.12 97.16
152 INT167872 Negative_regulation of Gene_expression of Foxp3 8 0.50 4.14 1.46 97.16
153 INT96145 Positive_regulation of HLA-S 2 0.46 5.61 1.19 97.16
154 INT78821 Negative_regulation of PGD 2 0.21 1.04 0.19 97.12
155 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 97.04
156 INT70303 Negative_regulation of Il4 19 0.52 12.9 8.54 97.04
157 INT160563 Localization of Il17a 34 0.74 26.53 10.24 97.00
158 INT78226 Gene_expression of Mbp 43 0.75 22.14 7.79 96.92
159 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 96.86
160 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 96.84
161 INT108485 Gene_expression of CXCL12 61 0.75 49.34 13.79 96.76
162 INT108482 Positive_regulation of Gene_expression of CXCL12 7 0.53 9.72 2.36 96.76
163 INT6596 Positive_regulation of HLA-DRB1 33 0.61 27.01 7.26 96.72
164 INT167519 Gene_expression of Ubl4 7 0.43 5.28 3.2 96.72
165 INT17741 Gene_expression of MBP 67 0.78 23.67 9.65 96.64
166 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93 96.64
167 INT43486 Positive_regulation of Ifng 52 0.69 32.71 24.77 96.64
168 INT234116 Positive_regulation of MID1 9 0.03 3.78 1.61 96.48
169 INT107585 Gene_expression of CCR2 35 0.71 26.44 14.75 96.44
170 INT73239 Negative_regulation of Gene_expression of Mbp 6 0.46 5.65 1.96 96.40
171 INT25 Positive_regulation of LAMC2 19 0.67 8.64 7.06 96.36
172 INT22949 Gene_expression of CCBE1 8 0.19 4.27 3.25 96.36
173 INT10915 Gene_expression of ITGAM 164 0.78 92.42 29.78 96.28
174 INT181363 Regulation of Ccl5 16 0.46 13.65 5.09 96.28
175 INT16258 Gene_expression of Ntf3 121 0.78 53.93 59.03 96.16
176 INT157960 Regulation of AQP4 11 0.48 21.36 3.06 95.96
177 INT10874 Negative_regulation of Twist1 89 0.50 36.84 11.32 95.92
178 INT46518 Localization of Mtr 12 0.65 1.31 6.55 95.80
179 INT256118 Negative_regulation of Sirt2 1 0.14 1.36 0.1 95.80
180 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 95.76
181 INT78023 Gene_expression of DDX41 13 0.65 23.55 3.84 95.72
182 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 95.68
183 INT4613 Positive_regulation of Sirt1 32 0.67 18.19 5.53 95.64
184 INT123908 Positive_regulation of HLA-DQB1 12 0.21 10.5 3.71 95.52
185 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 95.44
186 INT69304 Negative_regulation of Il10 47 0.59 36.88 19.79 95.32
187 INT56277 Binding of MYH9 3 0.36 2.37 1.11 95.28
188 INT69990 Negative_regulation of Nefl 11 0.59 2.82 3.38 95.16
189 INT14849 Binding of IgG-2a 12 0.39 5.96 6.06 95.12
190 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 95.08
191 INT67399 Negative_regulation of Transcription of Il12a 2 0.03 2.63 1.05 95.08
192 INT73240 Negative_regulation of Transcription of IFNG 1 0.41 0.92 0.76 95.08
193 INT57256 Gene_expression of HLA-DQA2 52 0.55 23.87 6.27 95.08
194 INT172084 Positive_regulation of Binding of TNF 21 0.50 15.31 6.06 95.08
195 INT235954 Gene_expression of Bcr 1 0.13 6.77 1.47 94.88
196 INT235931 Regulation of Gene_expression of Mog 1 0.15 1.58 0.36 94.88
197 INT235948 Regulation of Gene_expression of Bcr 1 0.08 1.58 0.36 94.88
198 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 94.76
199 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 94.72
200 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 94.40
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