D:Oral Lichen Planus

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pChart

Disease Term
Synonyms None
Documents 87
Hot Single Events 40
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Oral Lichen Planus. They are ordered first by their relevance to Oral Lichen Planus and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT182606 Binding of MSH2 and MSH3 1 0.12 1.4 0.21 63.48
2 INT182607 Binding of MLH1 and MSH3 1 0.04 0.81 0.11 63.24
3 INT238005 Binding of Cxcr3 and Cxcl10 2 0.38 3.73 1.42 45.64
4 INT190681 Binding of Bcl2 and Fkbp1a 1 0.01 0.46 0 23.28
5 INT238009 Binding of Cxcr3 and Cxcl9 3 0.40 4.01 1.37 5.00
6 INT237999 Binding of Cxcr3 and Cxcl11 2 0.45 3.49 1.11 5.00
7 INT252602 Binding of Cxcl10 and Ppig 1 0.08 1.55 0.96 5.00
8 INT237083 Binding of Cxcl10 and Cxcl9 2 0.39 3.19 0.87 5.00
9 INT237084 Binding of Cxcl9 and Cxcl11 2 0.34 3.19 0.87 5.00
10 INT252603 Ppig Positive_regulation of Gene_expression of Cx3cl1 1 0.10 1.8 0.69 5.00
11 INT252605 Ppig Positive_regulation of Gene_expression of Cx3cr1 1 0.09 1.81 0.69 5.00
12 INT252601 Binding of Cxcl10 and Cxcl11 1 0.34 1.68 0.6 5.00
13 INT252599 Negative_regulation of Cxcl10 Negative_regulation of Gene_expression of Cxcr3 1 0.45 0.49 0.29 5.00
14 INT252604 Negative_regulation of Cxcl10 Negative_regulation of Gene_expression of Hand1 1 0.24 0.5 0.29 5.00
15 INT252606 IFNA1 Positive_regulation of Gene_expression of Cxcl10 1 0.02 0.56 0.18 5.00
16 INT252600 Ppig Regulation of Hand1 1 0.06 0.43 0.17 5.00
17 INT252598 Ppig Regulation of Gene_expression of Hand1 1 0.06 0.43 0.17 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Oral Lichen Planus. They are ordered first by their pain relevance and then by number of times they were reported in Oral Lichen Planus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT182605 Gene_expression of Golga4 1 0.01 1.41 0.03 100.00
2 INT182625 Positive_regulation of Localization of MSH2 1 0.45 2.47 0 99.86
3 INT182624 Positive_regulation of Positive_regulation of MSH2 1 0.45 1.24 0 99.86
4 INT97131 Positive_regulation of CD14 25 0.67 12.03 4.21 99.84
5 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 99.84
6 INT133030 Positive_regulation of Gene_expression of TLR2 53 0.65 38.15 10.65 99.84
7 INT137206 Positive_regulation of TLR2 47 0.65 33.36 6.4 99.84
8 INT83602 Positive_regulation of Gene_expression of TRPV1 114 0.70 51.19 56.35 99.84
9 INT181745 Positive_regulation of MSH2 4 0.48 5.73 0.11 99.64
10 INT146916 Positive_regulation of Transcription of CD14 1 0.44 1.17 0.07 99.62
11 INT107986 Gene_expression of PMS1 2 0.19 1.58 0.39 99.56
12 INT107992 Gene_expression of MSH2 39 0.78 37.09 1.6 99.52
13 INT146545 Negative_regulation of Gene_expression of MSH2 17 0.56 18.87 0.51 99.52
14 INT182623 Localization of MSH2 3 0.77 5.49 0.12 99.52
15 INT146915 Transcription of CD14 7 0.67 3.7 1.36 99.44
16 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 99.38
17 INT104394 Positive_regulation of Gene_expression of Cxcl10 28 0.65 25.64 8.79 99.00
18 INT146914 Negative_regulation of TLR2 12 0.53 7.41 1.23 98.96
19 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17 98.88
20 INT104392 Gene_expression of Cxcl10 113 0.75 106.86 34.12 98.56
21 INT52350 Gene_expression of CD14 184 0.75 71.37 33.13 98.44
22 INT6852 Localization of TNF 883 0.81 705.95 270.84 97.82
23 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 96.04
24 INT97237 Transcription of TRPV1 33 0.72 10.56 12.4 94.88
25 INT99782 Negative_regulation of Cxcl10 21 0.55 18.4 6.5 94.56
26 INT21687 Positive_regulation of ras 143 0.58 97.34 27.31 93.08
27 INT19399 Gene_expression of Rf 43 0.36 33.39 13.53 92.12
28 INT10016 Negative_regulation of CD8A 81 0.42 56.68 13.15 91.68
29 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65 91.60
30 INT9383 Localization of TRPV1 98 0.81 33.23 46.24 90.68
31 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41 89.84
32 INT127888 Negative_regulation of HMMR 3 0.11 3.89 0.55 86.84
33 INT86909 Negative_regulation of MSH2 9 0.41 12.65 1.7 86.84
34 INT237054 Negative_regulation of Gene_expression of Cxcl10 11 0.56 10.26 3.4 84.52
35 INT95481 Regulation of Gene_expression of TRPV1 48 0.62 29.3 26.28 84.00
36 INT81688 Binding of ras 32 0.41 30.13 4.02 83.68
37 INT12844 Binding of TP63 15 0.47 10.57 3.38 83.28
38 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25 83.04
39 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24 83.04
40 INT101612 Protein_catabolism of HTT 3 0.86 1.44 0.05 80.32
41 INT153814 Localization of LPA 19 0.65 18.25 7.68 77.56
42 INT182627 Regulation of MSH2 1 0.26 2.27 0.18 72.28
43 INT147244 Regulation of MLH1 3 0.08 2.64 0.12 72.00
44 INT182621 Localization of MLH1 9 0.64 9.31 0.12 72.00
45 INT182626 Localization of MSH3 1 0.22 0.77 0.12 71.72
46 INT182622 Regulation of MSH3 1 0.08 0.77 0.12 71.72
47 INT163839 Regulation of CRAC1 2 0.45 1.42 0.54 71.44
48 INT182628 Localization of CRAC1 1 0.01 0.77 0.12 71.44
49 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 70.40
50 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 69.20
51 INT92142 Binding of MSH2 5 0.46 5.64 0.75 65.08
52 INT252582 Positive_regulation of Gene_expression of Ppig 3 0.12 2.62 1.13 58.80
53 INT127037 Gene_expression of Ppig 26 0.65 16.08 6.84 55.16
54 INT77076 Positive_regulation of Ppig 16 0.49 13.54 5.91 55.16
55 INT99787 Regulation of Cxcl10 9 0.43 6.37 3.02 53.60
56 INT170056 Binding of Cxcl10 11 0.45 12.72 5.32 45.64
57 INT174422 Binding of Cxcr3 24 0.47 26.09 8.34 45.36
58 INT32130 Gene_expression of TPSG1 12 0.51 6.59 1.88 38.40
59 INT168410 Gene_expression of Cxcr3 81 0.75 84.03 37.01 33.56
60 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86 24.72
61 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53 21.52
62 INT190676 Binding of Fkbp1a 15 0.36 3.11 0.28 20.40
63 INT91703 Negative_regulation of Myoz1 78 0.58 53.78 13.5 19.68
64 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89 17.36
65 INT190682 Negative_regulation of CDV3 1 0.57 1.38 0 17.36
66 INT190678 Binding of Nfatc1 6 0.26 1.04 0.83 5.04
67 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94 5.00
68 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
69 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46 5.00
70 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 5.00
71 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 5.00
72 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 5.00
73 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 5.00
74 INT114751 Gene_expression of Mapk1 137 0.76 60.14 39.98 5.00
75 INT95788 Positive_regulation of Positive_regulation of Mapk1 83 0.69 24.75 25.84 5.00
76 INT8775 Binding of IGHE 167 0.48 102.61 23.54 5.00
77 INT14701 Negative_regulation of IFNA1 118 0.54 84.19 20.08 5.00
78 INT104395 Gene_expression of Cxcl9 83 0.76 73.1 19.79 5.00
79 INT38056 Localization of Crp 71 0.78 53.14 17.03 5.00
80 INT94467 Positive_regulation of Hand1 71 0.58 59 16.96 5.00
81 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36 5.00
82 INT16321 Gene_expression of Cd3e 111 0.72 49.9 14.21 5.00
83 INT99780 Positive_regulation of Cxcl10 43 0.69 39.67 13.27 5.00
84 INT150676 Positive_regulation of Gene_expression of Mapk1 30 0.45 10.06 12.37 5.00
85 INT176607 Gene_expression of Cx3cl1 27 0.75 19.51 11.32 5.00
86 INT94465 Positive_regulation of Gene_expression of Hand1 43 0.38 29.76 10.88 5.00
87 INT99784 Positive_regulation of Cxcr3 22 0.66 22.44 10.36 5.00
88 INT168642 Gene_expression of Cx3cr1 15 0.77 21.73 8.1 5.00
89 INT104387 Positive_regulation of Cxcl9 24 0.67 22.26 7.87 5.00
90 INT174432 Transcription of Cxcr3 8 0.68 15.73 7.32 5.00
91 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41 5.00
92 INT237051 Gene_expression of Cxcl11 24 0.64 25.74 5.77 5.00
93 INT14470 Gene_expression of HCC 83 0.67 110.55 4.61 5.00
94 INT104389 Positive_regulation of Gene_expression of Cxcl9 15 0.49 17.42 4.59 5.00
95 INT138916 Transcription of Cxcl9 13 0.68 9.88 3.96 5.00
96 INT127039 Negative_regulation of Ppig 13 0.21 5.29 3.87 5.00
97 INT47674 Positive_regulation of Myoz1 21 0.54 4.37 3.57 5.00
98 INT160409 Transcription of Cxcl10 9 0.65 7.95 3.53 5.00
99 INT9999 Regulation of Gene_expression of IGHE 32 0.60 15.75 3.53 5.00
100 INT133374 Gene_expression of Pdha1 3 0.12 1.44 2.98 5.00
101 INT94463 Regulation of Gene_expression of Hand1 10 0.36 5.17 2.72 5.00
102 INT24871 Negative_regulation of Binding of IGHE 10 0.58 2.87 2.64 5.00
103 INT72782 Positive_regulation of HCC 41 0.40 63.74 2.46 5.00
104 INT170053 Binding of Cxcl9 5 0.46 6.34 2.43 5.00
105 INT220165 Positive_regulation of Cxcl11 8 0.60 9.67 2.29 5.00
106 INT142677 Negative_regulation of Positive_regulation of Bcl2 4 0.36 3.09 2.24 5.00
107 INT138920 Regulation of Gene_expression of Cxcl10 5 0.59 5.72 2.1 5.00
108 INT92056 Transcription of Il12b 8 0.69 4.75 1.95 5.00
109 INT135540 Negative_regulation of Bax 16 0.48 11.8 1.89 5.00
110 INT153743 Negative_regulation of Localization of Crp 2 0.14 1.83 1.84 5.00
111 INT114730 Phosphorylation of Myoz1 8 0.14 1.15 1.71 5.00
112 INT22058 Positive_regulation of Igha 7 0.49 5.29 1.69 5.00
113 INT105535 Gene_expression of Myoz1 27 0.13 3.94 1.5 5.00
114 INT109512 Negative_regulation of Gene_expression of Bax 12 0.42 8.04 1.44 5.00
115 INT153218 Positive_regulation of Transcription of Cxcl9 4 0.45 3.57 1.42 5.00
116 INT138913 Negative_regulation of Gene_expression of Cxcl9 8 0.58 6.22 1.36 5.00
117 INT138911 Negative_regulation of Cxcl9 5 0.42 3.31 1.35 5.00
118 INT252588 Transcription of Cxcl11 1 0.60 3.61 1.24 5.00
119 INT99325 Positive_regulation of Pdha1 6 0.49 1.55 1.22 5.00
120 INT237047 Positive_regulation of Gene_expression of Cxcl11 5 0.43 5.04 1.17 5.00
121 INT174447 Regulation of Cxcr3 1 0.60 2.68 1.12 5.00
122 INT99781 Positive_regulation of Negative_regulation of Cxcl10 2 0.50 0.97 0.8 5.00
123 INT190675 Phosphorylation of Nfatc1 6 0.56 0.68 0.76 5.00
124 INT185049 Transcription of Hand1 5 0.47 1.84 0.71 5.00
125 INT196866 Localization of Ppig 2 0.17 0.58 0.64 5.00
126 INT252587 Binding of Cxcl11 1 0.30 1.62 0.6 5.00
127 INT93358 Negative_regulation of Positive_regulation of Trp53 9 0.41 3.95 0.6 5.00
128 INT237990 Regulation of Gene_expression of Cxcl9 2 0.44 1.91 0.58 5.00
129 INT103782 Binding of Ppig 5 0.12 2.57 0.58 5.00
130 INT125821 Regulation of Positive_regulation of IGHE 6 0.40 5.38 0.53 5.00
131 INT252586 Regulation of Transcription of Cxcl10 1 0.43 0.81 0.42 5.00
132 INT252585 Regulation of Cxcl11 1 0.51 0.95 0.41 5.00
133 INT252596 Positive_regulation of Binding of Cxcr3 1 0.49 1.19 0.41 5.00
134 INT252590 Regulation of Transcription of Hand1 1 0.36 0.76 0.36 5.00
135 INT190677 Localization of Nfatc1 4 0.57 0.67 0.35 5.00
136 INT252595 Regulation of Negative_regulation of Ppig 1 0.12 0.78 0.34 5.00
137 INT252581 Positive_regulation of Positive_regulation of Ppig 1 0.11 1.26 0.34 5.00
138 INT252589 Regulation of Negative_regulation of Cxcl10 1 0.43 0.77 0.34 5.00
139 INT239861 Gene_expression of Itga2 5 0.65 1.32 0.32 5.00
140 INT252592 Negative_regulation of Positive_regulation of Cxcl9 1 0.41 0.97 0.24 5.00
141 INT252591 Negative_regulation of Positive_regulation of Cxcl10 1 0.40 0.97 0.24 5.00
142 INT252583 Positive_regulation of Binding of Ppig 1 0.12 0.46 0.16 5.00
143 INT190679 Localization of Myoz1 2 0.16 0.57 0.11 5.00
144 INT252584 Positive_regulation of Transcription of Cxcl10 1 0.44 0.71 0.1 5.00
145 INT252593 Negative_regulation of Negative_regulation of Cxcl10 1 0.40 0.36 0.09 5.00
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