D:Orbital Diseases

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pChart

Disease Term
Synonyms DISEASE ORBITAL, Diseases Orbital, Orbital Disease
Documents 24
Hot Single Events 2
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Orbital Diseases. They are ordered first by their relevance to Orbital Diseases and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5 5.00
2 INT181862 Binding of MPO and PRTN3 2 0.16 1.18 0.38 5.00
3 INT318299 Binding of F2 and PRTN3 1 0.01 1.92 0.33 5.00
4 INT318303 Negative_regulation of Myoz1 Negative_regulation of Transcription of IL2 1 0.00 0.75 0.21 5.00
5 INT318298 MECOM Negative_regulation of Binding of CD28 1 0.00 1.08 0.18 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Orbital Diseases. They are ordered first by their pain relevance and then by number of times they were reported in Orbital Diseases. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT16997 Binding of PRTN3 34 0.48 33.44 6.45 94.40
2 INT12324 Positive_regulation of PRTN3 26 0.70 18.82 4.55 90.28
3 INT105670 Gene_expression of AAVS1 131 0.75 49.24 12.95 61.12
4 INT85078 Positive_regulation of PCNA 36 0.49 17.06 2.81 17.24
5 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 16.28
6 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
7 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
8 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
9 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
10 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
11 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
12 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33 5.00
13 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 5.00
14 INT23222 Binding of Phax 52 0.31 7.61 30.4 5.00
15 INT153776 Positive_regulation of IL17A 42 0.64 34.58 14.82 5.00
16 INT67855 Negative_regulation of PPIG 64 0.57 17.83 13.54 5.00
17 INT91703 Negative_regulation of Myoz1 78 0.58 53.78 13.5 5.00
18 INT60764 Positive_regulation of PPIG 39 0.67 17.08 13.48 5.00
19 INT51014 Transcription of IL2 42 0.71 21.56 12.7 5.00
20 INT50580 Binding of PPIG 39 0.36 11.17 12.34 5.00
21 INT16772 Gene_expression of MPO 81 0.78 90.98 11.9 5.00
22 INT70877 Gene_expression of PPIG 72 0.75 22.39 10.93 5.00
23 INT73504 Binding of CD28 35 0.45 15.99 10.04 5.00
24 INT44602 Gene_expression of TNFSF13B 37 0.75 30.98 9.96 5.00
25 INT56223 Positive_regulation of MPO 35 0.70 43 8.2 5.00
26 INT155010 Positive_regulation of Gene_expression of IL17A 23 0.64 20.17 7.15 5.00
27 INT211133 Negative_regulation of MTX1 8 0.19 3.86 4.87 5.00
28 INT67279 Localization of PRTN3 11 0.50 14.18 4.3 5.00
29 INT150222 Positive_regulation of Gene_expression of TNFSF13B 12 0.11 7.49 2.43 5.00
30 INT144652 Negative_regulation of Binding of CD28 6 0.55 3.09 2.28 5.00
31 INT171010 Binding of IL5 6 0.36 4.11 2.12 5.00
32 INT254308 Negative_regulation of TNFSF13B 10 0.42 5.12 1.25 5.00
33 INT182852 Regulation of AAVS1 4 0.12 4.6 1.03 5.00
34 INT190418 Positive_regulation of AAVS1 15 0.49 4.71 0.98 5.00
35 INT272511 Positive_regulation of DMPK 8 0.54 6.85 0.72 5.00
36 INT154180 Negative_regulation of SYK 3 0.43 4.67 0.5 5.00
37 INT318301 Negative_regulation of DHODH 1 0.03 0.6 0.44 5.00
38 INT274203 Positive_regulation of PABPN1 1 0.16 2.41 0.37 5.00
39 INT229392 Negative_regulation of Positive_regulation of MPO 2 0.20 2.18 0.32 5.00
40 INT138715 Gene_expression of POLG 12 0.66 6.97 0.23 5.00
41 INT182854 Negative_regulation of AAVS1 4 0.06 1.98 0.15 5.00
42 INT318300 Binding of CD52 1 0.10 1.16 0.07 5.00
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