D:Organ Transplantation

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pChart

Disease Term
Synonyms Organ Transplant, Transplant Rejection
Documents 471
Hot Single Events 160
Hot Interactions 17

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Organ Transplantation. They are ordered first by their relevance to Organ Transplantation and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT320794 Binding of VEGFA and Flt4 4 0.08 3.04 0.27 99.72
2 INT175196 Binding of NCOR1 and NUP62 1 0.02 0.84 0.12 91.52
3 INT164517 CABIN1 Positive_regulation of Transcription of IL2 1 0.13 0.35 0.22 91.32
4 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 88.04
5 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21 88.04
6 INT347531 Binding of Nrp2 and Sema3b 1 0.04 0.99 0.28 87.08
7 INT299793 Positive_regulation of Binding of CD86 and CTLA4 1 0.17 1.64 0.63 85.80
8 INT299792 Positive_regulation of Binding of CD80 and CTLA4 1 0.17 1.63 0.63 85.80
9 INT291625 Binding of CSTA and RAPGEF5 1 0.03 4.81 0.37 85.64
10 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 85.48
11 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 85.48
12 INT158400 Binding of CD80 and CD86 3 0.36 0.76 0.48 84.80
13 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12 83.00
14 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5 83.00
15 INT299791 Negative_regulation of Binding of CD28 and CTLA4 1 0.18 0.77 0.32 83.00
16 INT320021 Prkaca Regulation of Positive_regulation of Kcnma1 1 0.00 0.54 1 82.56
17 INT343918 IgG Positive_regulation of Phosphorylation of MAPK1 1 0.01 3.57 0.91 81.60
18 INT220053 Il10 Positive_regulation of Ido1 1 0.14 0.74 0.19 78.28
19 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91 77.52
20 INT220050 Ctla4 Positive_regulation of Ido1 1 0.31 1.45 0.38 77.36
21 INT273495 GBP4 Negative_regulation of IMPDH1 1 0.03 0.2 0 75.40
22 INT252366 Binding of RUNX1 and CD80 1 0.01 0.54 0.2 72.80
23 INT293360 Binding of CSH1 and FKBP1A 1 0.00 0.14 0.05 72.04
24 INT293368 Binding of CSH1 and Ppia 1 0.00 0.19 0.03 72.04
25 INT328484 Ptgs1 Positive_regulation of Ros1 1 0.00 0.58 0.16 71.92
26 INT252367 Binding of RUNX1 and CTLA4 1 0.02 0.48 0.18 71.20
27 INT293367 Binding of CABIN1 and Ppia 1 0.00 0.19 0.03 71.12
28 INT293358 Binding of FKBP1A and CABIN1 1 0.00 0.07 0.03 71.12
29 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62 69.76
30 INT278156 Negative_regulation of Trib3 Negative_regulation of Akt1 1 0.00 0.45 0.1 68.64
31 INT293354 Binding of CSH1 and Fkbp1a 1 0.00 0.12 0 65.88
32 INT293362 CSH1 Negative_regulation of Gene_expression of IL2 1 0.01 0.12 0 65.88
33 INT293355 Binding of Fkbp1a and CABIN1 1 0.00 0.12 0 63.88
34 INT227774 Negative_regulation of Binding of Cd40 and Cd40lg 1 0.31 0.29 0.03 60.56
35 INT277745 Trib3 Regulation of Ccnd1 1 0.00 0.41 0.03 59.72
36 INT186125 Negative_regulation of Binding of CD2 and CD58 3 0.12 3.04 1.06 58.40
37 INT343910 TLR4 Regulation of Gene_expression of Icam1 1 0.04 1.3 0.22 57.76
38 INT186128 Binding of CD2 and CD58 8 0.10 7.59 2.76 57.04
39 INT293366 Binding of CABIN1 and Fkbp1a 1 0.00 0.05 0 53.04
40 INT220052 Binding of Col7a1 and Cia1 1 0.01 1.11 0.38 34.44
41 INT177947 IFN1@ Positive_regulation of Gene_expression of HLA-E 1 0.09 0.59 0.03 29.60
42 INT177948 IFNG Positive_regulation of Gene_expression of HLA-E 1 0.04 0.59 0.03 29.20
43 INT293357 RORC Regulation of PPP2R4 1 0.00 0 0 23.32
44 INT227543 Mtx1 Positive_regulation of Prep 1 0.22 1.19 1.92 23.24
45 INT227542 Mtx1 Positive_regulation of Binding of Prep 1 0.23 1.2 1.92 23.24
46 INT227545 Hspa9 Positive_regulation of Prep 1 0.18 0.59 0.96 22.60
47 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72 22.20
48 INT293353 Binding of CD8A and Cd3e 1 0.01 0.07 0.04 22.20
49 INT291623 Binding of CRP and CSTA 1 0.03 0.38 0 14.32
50 INT343859 Binding of IRF6 and TBCE 1 0.01 1.1 0.51 7.76
51 INT343860 Binding of CD14 and TBCE 1 0.03 1.1 0.51 7.76
52 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 7.20
53 INT343834 Binding of CD14 and IRF6 1 0.02 2.08 0.9 6.80
54 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 5.00
55 INT69032 IL18 Positive_regulation of IFNA1 12 0.23 7.87 3.83 5.00
56 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 5.00
57 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95 5.00
58 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95 5.00
59 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63 5.00
60 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42 5.00
61 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32 5.00
62 INT225104 CNR1 Positive_regulation of Gene_expression of RETNLB 1 0.01 1.41 1.14 5.00
63 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03 5.00
64 INT276964 Binding of Tlr1 and Tlr2 11 0.24 4.22 0.89 5.00
65 INT343847 IRF6 Positive_regulation of TBCE 1 0.01 1.11 0.87 5.00
66 INT226337 Binding of IL10 and IL10RA 2 0.24 2.51 0.85 5.00
67 INT226340 Binding of CD4 and IFNA1 3 0.03 3.84 0.85 5.00
68 INT343829 TLR1 Positive_regulation of TBCE 1 0.03 0.96 0.85 5.00
69 INT276988 Binding of Tlr6 and Tlr2 11 0.26 4.89 0.79 5.00
70 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79 5.00
71 INT182814 Binding of ICAM1 and PECAM1 2 0.02 3.32 0.77 5.00
72 INT170127 Binding of ITGAL and PECAM1 2 0.01 2.71 0.75 5.00
73 INT226540 Binding of IL24 and Il20ra 1 0.00 0.97 0.71 5.00
74 INT172097 Binding of HLA-E and Trav6-3 10 0.02 3.71 0.71 5.00
75 INT230336 IL4 Regulation of IL5 2 0.04 0.82 0.67 5.00
76 INT343851 Positive_regulation of Binding of IRF6 and TLR4 1 0.07 1.96 0.66 5.00
77 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63 5.00
78 INT292893 TNF Regulation of IL8 2 0.27 1.3 0.63 5.00
79 INT182819 Binding of CD63 and PECAM1 1 0.00 1.63 0.61 5.00
80 INT227544 Hspa9 Regulation of Gene_expression of Prep 1 0.15 0.57 0.61 5.00
81 INT182815 Binding of CD63 and ICAM1 1 0.00 1.63 0.61 5.00
82 INT220051 Fcgr4 Positive_regulation of Gene_expression of Ido1 1 0.01 1.24 0.55 5.00
83 INT343913 Binding of FOS and Smad3 1 0.19 0.92 0.54 5.00
84 INT226360 IL18 Positive_regulation of Gene_expression of IL4 1 0.05 2.66 0.54 5.00
85 INT226348 IL18 Positive_regulation of Gene_expression of IL13 1 0.03 2.66 0.54 5.00
86 INT226517 Binding of IL19 and Il20ra 1 0.00 0.69 0.53 5.00
87 INT220054 Regulation of IFN1@ Negative_regulation of Cia1 1 0.18 1.19 0.52 5.00
88 INT343838 EDA Positive_regulation of TLR4 1 0.11 0.87 0.51 5.00
89 INT182813 EEF1A2 Negative_regulation of ITGAL 1 0.10 1.53 0.51 5.00
90 INT254125 Binding of Bcl2a1a and Tlr4 Positive_regulation of Localization of Il6 1 0.00 1.23 0.5 5.00
91 INT343825 IRF6 Regulation of Gene_expression of FUT1 1 0.00 1.74 0.5 5.00
92 INT254119 Binding of Bcl2a1a and Tlr4 1 0.01 1.34 0.49 5.00
93 INT220055 IFN1@ Negative_regulation of Cia1 1 0.24 1.12 0.48 5.00
94 INT343846 MAPK1 Positive_regulation of FOS 1 0.04 1.29 0.44 5.00
95 INT226341 S1PR1 Regulation of MBTPS1 1 0.00 0.76 0.44 5.00
96 INT179432 Binding of pcp and AICDA 1 0.03 3.51 0.43 5.00
97 INT254120 Aliq1 Positive_regulation of Tbce 1 0.00 0.68 0.43 5.00
98 INT343853 IRF6 Positive_regulation of PECAM1 1 0.00 0.53 0.43 5.00
99 INT299789 IL4 Negative_regulation of Gene_expression of RAE1 1 0.00 0.84 0.41 5.00
100 INT343916 Hspa1a Positive_regulation of Gene_expression of TNF 1 0.16 1.17 0.41 5.00
101 INT343919 Hspa1a Positive_regulation of Gene_expression of IL6 1 0.02 1.17 0.4 5.00
102 INT343907 Hspa1a Positive_regulation of Gene_expression of Cxcl2 1 0.01 1.17 0.4 5.00
103 INT343844 Binding of IRF6 and LY96 1 0.01 1.03 0.4 5.00
104 INT299786 IL4 Negative_regulation of Gene_expression of CD5 1 0.07 0.82 0.4 5.00
105 INT292887 IL4 Regulation of IL12A 1 0.01 0.25 0.39 5.00
106 INT292891 IL2 Regulation of IL5 1 0.02 0.25 0.39 5.00
107 INT292892 IL4 Regulation of IL8 1 0.01 0.25 0.39 5.00
108 INT295478 IRF6 Positive_regulation of Positive_regulation of TLR4 2 0.20 0.78 0.39 5.00
109 INT292889 IL2 Regulation of IL12A 1 0.01 0.25 0.39 5.00
110 INT292890 TNF Regulation of IL5 1 0.02 0.25 0.39 5.00
111 INT329799 Binding of CD14 and LY96 2 0.04 1.02 0.39 5.00
112 INT292888 TNF Regulation of IL12A 1 0.02 0.25 0.39 5.00
113 INT292886 IL2 Regulation of IL8 1 0.03 0.25 0.39 5.00
114 INT226381 S1PR1 Positive_regulation of Gene_expression of IK 1 0.00 0.64 0.38 5.00
115 INT299790 IL4 Negative_regulation of Gene_expression of NPEPPS 1 0.00 0.86 0.37 5.00
116 INT299788 INCENP Negative_regulation of Gene_expression of NPEPPS 1 0.00 0.86 0.37 5.00
117 INT226350 MBTPS1 Negative_regulation of Gene_expression of CD4 1 0.03 0.61 0.37 5.00
118 INT226374 Negative_regulation of Binding of CD4 and IFNA1 1 0.03 0.66 0.37 5.00
119 INT254123 Binding of Adora2b and Rai1 1 0.24 0.75 0.35 5.00
120 INT343912 Fgg Positive_regulation of Gene_expression of IL6 1 0.00 0.83 0.35 5.00
121 INT343857 Binding of ABCC8 and LY96 1 0.02 0.96 0.34 5.00
122 INT225119 Foxm1 Regulation of Localization of TGFB1 1 0.01 0.63 0.34 5.00
123 INT262307 CAPNS1 Regulation of TAF9 1 0.04 1.23 0.33 5.00
124 INT254122 Adora2a Regulation of Aliq1 1 0.01 0.85 0.3 5.00
125 INT226512 Il1rl1 Positive_regulation of Jun 1 0.12 0.34 0.29 5.00
126 INT226375 INCENP Positive_regulation of Regulation of TH1L 1 0.01 0.57 0.29 5.00
127 INT226376 INCENP Negative_regulation of Gene_expression of TH1L 1 0.00 0.61 0.29 5.00
128 INT226505 Il1rl1 Positive_regulation of Mapk8 1 0.04 0.4 0.29 5.00
129 INT226509 Il1rl1 Positive_regulation of Gene_expression of Mapk8 1 0.05 0.4 0.29 5.00
130 INT225101 TGFB1 Positive_regulation of Localization of COL1A1 1 0.03 0.59 0.28 5.00
131 INT182817 EEF1A2 Positive_regulation of BMP2 1 0.26 1.62 0.28 5.00
132 INT225100 TGFB1 Positive_regulation of Gene_expression of COL1A1 1 0.04 0.59 0.28 5.00
133 INT258861 Binding of HLA-DOA and HLA-DRB1 2 0.14 1.88 0.28 5.00
134 INT226383 IL22 Positive_regulation of Gene_expression of INCENP 1 0.00 0.85 0.28 5.00
135 INT343856 Binding of S100A9 and ABCC8 1 0.04 0.9 0.28 5.00
136 INT343832 Positive_regulation of EDA Positive_regulation of TLR4 1 0.11 0.43 0.27 5.00
137 INT226363 IK Positive_regulation of IL22 1 0.00 0.87 0.27 5.00
138 INT179566 Binding of C1qa and Ywhaq 1 0.00 0.56 0.26 5.00
139 INT226343 Binding of IFNA1 and IL26 1 0.02 0.18 0.26 5.00
140 INT226352 Binding of IL22 and IL22RA1 1 0.00 0.17 0.26 5.00
141 INT226342 Binding of IL20RA and IL26 1 0.00 0.18 0.26 5.00
142 INT226355 IL9 Positive_regulation of IL22 1 0.02 0.86 0.26 5.00
143 INT226537 Hand2 Positive_regulation of IL22 1 0.02 0.86 0.26 5.00
144 INT226361 Binding of IL10 and IL22RA1 1 0.00 0.17 0.26 5.00
145 INT254124 Binding of Bcl2a1a and Tlr4 Positive_regulation of Localization of Tbxa2r 1 0.00 0.62 0.25 5.00
146 INT343864 EDA Positive_regulation of Gene_expression of TLR4 1 0.11 0.44 0.25 5.00
147 INT180718 Binding of SARS and ACE2 3 0.12 7.76 0.25 5.00
148 INT226533 Il25 Positive_regulation of Gene_expression of IL13 1 0.01 0.64 0.24 5.00
149 INT343914 Hmgb1 Positive_regulation of Gene_expression of IL12A 1 0.01 0.41 0.24 5.00
150 INT225098 ZNF630 Regulation of Localization of TGFB1 1 0.01 0.44 0.24 5.00
151 INT225105 ZNF630 Regulation of TGFB1 1 0.01 0.44 0.24 5.00
152 INT343906 Hmgb1 Positive_regulation of Gene_expression of Cd40 1 0.05 0.41 0.24 5.00
153 INT343911 Mthfd1 Positive_regulation of Gene_expression of IL12A 1 0.00 0.41 0.23 5.00
154 INT225118 Foxm1 Positive_regulation of Gene_expression of MMP2 1 0.01 0.34 0.23 5.00
155 INT279503 Binding of C1s and C1ra 1 0.03 0.58 0.22 5.00
156 INT250553 Binding of RS1 and SUGT1 3 0.00 3.36 0.22 5.00
157 INT225117 Foxm1 Regulation of Gene_expression of FN1 1 0.01 0.4 0.22 5.00
158 INT182816 EEF1A2 Negative_regulation of CRP 1 0.28 1.84 0.21 5.00
159 INT334379 Ros1 Regulation of Cat 1 0.04 0.08 0.21 5.00
160 INT299787 Binding of IL2 and ISG20 1 0.04 0.82 0.21 5.00
161 INT343849 Binding of FAS and TLR4 1 0.04 0.32 0.21 5.00
162 INT225103 ZNF630 Negative_regulation of CNR2 1 0.01 0.17 0.21 5.00
163 INT225097 ZNF630 Negative_regulation of CNR2 Positive_regulation of Gene_expression of COL1A1 1 0.00 0.17 0.21 5.00
164 INT226511 Gene_expression of Il25 Positive_regulation of Gene_expression of Hand2 1 0.01 0.95 0.2 5.00
165 INT226373 IL19 Positive_regulation of Gene_expression of IL5 1 0.02 0.56 0.2 5.00
166 INT226336 IL19 Positive_regulation of Gene_expression of IL13 1 0.01 0.56 0.2 5.00
167 INT226379 IL19 Positive_regulation of IL5 1 0.02 0.55 0.2 5.00
168 INT226529 BTPs Negative_regulation of TH1L 1 0.05 0.22 0.2 5.00
169 INT226377 IL19 Positive_regulation of IL13 1 0.01 0.56 0.2 5.00
170 INT226514 BTPs Negative_regulation of Gene_expression of Hand2 1 0.03 0.22 0.2 5.00
171 INT225099 ZNF630 Positive_regulation of Gene_expression of COL1A1 1 0.00 0.17 0.2 5.00
172 INT226384 INCENP Positive_regulation of IL19 1 0.00 0.58 0.2 5.00
173 INT254121 Binding of Tbce and Aliq1 1 0.00 0.69 0.2 5.00
174 INT226368 Positive_regulation of TNF Positive_regulation of Positive_regulation of IGHE 1 0.11 0.92 0.2 5.00
175 INT226338 IL19 Positive_regulation of Gene_expression of IL10 1 0.01 0.56 0.2 5.00
176 INT226333 IL21 Positive_regulation of Binding of STAT4 1 0.03 0.57 0.2 5.00
177 INT226523 BTPs Negative_regulation of Gene_expression of TH1L 1 0.05 0.22 0.2 5.00
178 INT226542 Negative_regulation of Adora2b Positive_regulation of IL19 1 0.08 0.58 0.2 5.00
179 INT226510 BTPs Negative_regulation of Hand2 1 0.03 0.22 0.2 5.00
180 INT226369 IL19 Positive_regulation of IL4 1 0.03 0.55 0.2 5.00
181 INT226525 Adora2b Positive_regulation of IL19 1 0.03 0.58 0.2 5.00
182 INT226351 IL19 Positive_regulation of IL10 1 0.01 0.55 0.2 5.00
183 INT226353 IL19 Positive_regulation of Gene_expression of IL4 1 0.03 0.56 0.2 5.00
184 INT343837 TICAM1 Positive_regulation of IRF3 1 0.03 0.19 0.19 5.00
185 INT226335 Binding of IL20 and IL20RB 1 0.03 0.29 0.19 5.00
186 INT343831 TICAM1 Positive_regulation of Gene_expression of TLR4 1 0.11 0.19 0.19 5.00
187 INT226528 BTPs Negative_regulation of Gene_expression of IL2 1 0.04 0.22 0.19 5.00
188 INT226385 Binding of IL24 and IL22RA1 1 0.00 0.28 0.19 5.00
189 INT343827 MIRLET7I Regulation of Gene_expression of TLR4 1 0.00 0.13 0.19 5.00
190 INT226362 Binding of IL20 and IL22RA1 1 0.00 0.28 0.19 5.00
191 INT343841 ZBP1 Regulation of Transcription of IFN1@ 1 0.00 0.2 0.19 5.00
192 INT226370 Binding of IL24 and IL20RB 1 0.03 0.28 0.19 5.00
193 INT226345 Binding of IL24 and IL20RA 1 0.00 0.23 0.19 5.00
194 INT226349 Binding of IL19 and IL20RA 1 0.00 0.24 0.19 5.00
195 INT279507 Serping1 Negative_regulation of Gene_expression of C3 1 0.03 1.12 0.19 5.00
196 INT343854 TIRAP Positive_regulation of IRF3 1 0.06 0.19 0.19 5.00
197 INT279500 Serping1 Negative_regulation of Transcription of C3 1 0.03 1.12 0.19 5.00
198 INT226346 Binding of IL21 and Positive_regulation of Positive_regulation of JAK3 1 0.08 0.48 0.18 5.00
199 INT226372 INCENP Negative_regulation of Gene_expression of IL5 1 0.00 1.12 0.18 5.00
200 INT226344 Gene_expression of IL9 Positive_regulation of CCL5 1 0.07 1.03 0.18 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Organ Transplantation. They are ordered first by their pain relevance and then by number of times they were reported in Organ Transplantation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT97062 Binding of PML 10 0.41 11.63 1.65 99.84
2 INT227519 Positive_regulation of Hspa9 22 0.55 16.38 3.83 99.80
3 INT45275 Gene_expression of CSH1 39 0.62 9.39 5.85 99.78
4 INT278141 Negative_regulation of Negative_regulation of Jak3 1 0.20 0.66 0.15 99.64
5 INT24889 Negative_regulation of CABIN1 36 0.48 16.76 4.73 99.40
6 INT93045 Negative_regulation of Gene_expression of Hand2 31 0.43 25.26 9.24 99.38
7 INT132573 Negative_regulation of Gene_expression of TH1L 16 0.42 11.52 5.76 99.38
8 INT138543 Negative_regulation of Cd28 3 0.11 2.1 1.01 99.36
9 INT145299 Negative_regulation of Jak3 25 0.48 17.66 7.13 99.24
10 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 99.14
11 INT73731 Binding of RAPH1 9 0.33 14.58 0.5 99.08
12 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 99.06
13 INT37912 Negative_regulation of Chd7 10 0.26 5.84 4.46 99.04
14 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 98.90
15 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 98.88
16 INT91703 Negative_regulation of Myoz1 78 0.58 53.78 13.5 98.58
17 INT106307 Positive_regulation of UROD 27 0.49 16.63 2.19 98.56
18 INT220335 Gene_expression of UROD 34 0.54 24.53 2.89 98.32
19 INT220338 Positive_regulation of Gene_expression of UROD 2 0.49 3.55 0.69 98.32
20 INT173505 Localization of Hand2 63 0.57 45.32 13.66 98.28
21 INT113987 Localization of IK 29 0.23 16.73 8.25 98.20
22 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 98.16
23 INT50580 Binding of PPIG 39 0.36 11.17 12.34 98.16
24 INT164520 Regulation of CABIN1 2 0.26 0.1 0.13 98.00
25 INT175176 Positive_regulation of Binding of Fkbp4 1 0.49 0.68 0.05 97.88
26 INT4403 Binding of CYP2B6 113 0.48 21.17 33.83 97.76
27 INT6481 Binding of TNF 624 0.48 510.2 214.82 97.64
28 INT293345 Negative_regulation of Binding of FKBP1A 1 0.02 0.19 0.13 97.56
29 INT73982 Gene_expression of Hmox1 141 0.78 119.43 32.17 97.28
30 INT80228 Positive_regulation of Gene_expression of Hmox1 68 0.70 62.88 14.01 97.28
31 INT175175 Binding of Fkbp4 1 0.36 0.68 0.05 97.28
32 INT23401 Gene_expression of HLA-DOA 91 0.30 38.21 5.52 97.20
33 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53 97.12
34 INT75137 Regulation of Akt1 74 0.48 37.89 9.7 97.04
35 INT212593 Negative_regulation of IMPDH1 4 0.10 3.01 0.07 96.88
36 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 96.84
37 INT201091 Regulation of HLA-DOA 5 0.20 3.6 0.44 96.76
38 INT230251 Binding of FKBP1A 6 0.28 2.24 0.94 96.76
39 INT75540 Positive_regulation of TH1L 62 0.67 43.45 15.02 96.76
40 INT170308 Gene_expression of Ido1 159 0.75 69.51 15.98 96.72
41 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 96.72
42 INT170323 Regulation of Gene_expression of Ido1 11 0.60 8.74 2.33 96.72
43 INT374 Positive_regulation of Ldha 212 0.70 107.08 47.43 96.36
44 INT100220 Negative_regulation of Src 13 0.41 6.37 4.93 96.32
45 INT10049 Negative_regulation of SERPINA1 56 0.59 44.52 9.93 96.24
46 INT164519 Gene_expression of FKBP1A 2 0.39 0.22 0.19 96.12
47 INT164518 Gene_expression of PPIA 7 0.75 3.92 0.5 96.12
48 INT170311 Negative_regulation of Ido1 16 0.48 14.47 4.81 96.08
49 INT96148 Gene_expression of HLA-S 3 0.72 17.33 3.99 96.00
50 INT89966 Negative_regulation of Fas 26 0.58 24.83 3.5 95.88
51 INT23402 Binding of HLA-DOA 74 0.48 52.01 10.89 95.76
52 INT227523 Localization of Hspa9 9 0.60 5.26 3.18 95.72
53 INT273497 Negative_regulation of IMPDH2 1 0.02 0.36 0 95.44
54 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21 95.40
55 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7 95.12
56 INT103699 Negative_regulation of IL15 5 0.24 2.42 1.12 95.12
57 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 94.92
58 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 94.76
59 INT19330 Binding of HLA-A 99 0.48 76.26 22.85 94.64
60 INT257447 Binding of TBCE 4 0.08 4.68 0.66 94.64
61 INT91659 Negative_regulation of Localization of IL12A 8 0.14 3.9 1.75 94.08
62 INT28122 Gene_expression of MSC 111 0.58 26.83 6.57 94.04
63 INT91667 Localization of IL12A 39 0.74 25.51 7.36 93.76
64 INT19617 Negative_regulation of CD86 12 0.42 3.68 1.77 93.76
65 INT97134 Negative_regulation of CD80 8 0.57 5.09 2.11 93.04
66 INT20166 Negative_regulation of Mtor 32 0.56 10.64 10.25 92.88
67 INT16964 Binding of IFNG 27 0.48 14.31 2.45 92.52
68 INT174527 Negative_regulation of CD28 13 0.35 5.06 2.65 92.40
69 INT13435 Positive_regulation of RTCA 31 0.60 7.19 8.5 91.72
70 INT60500 Negative_regulation of Tbce 21 0.41 13.3 11.1 91.68
71 INT26545 Gene_expression of Hras1 173 0.78 79.54 13.21 91.40
72 INT62629 Localization of CNR1 35 0.76 11.86 16.3 91.36
73 INT243382 Positive_regulation of CSTA 4 0.05 14.65 0.12 91.20
74 INT83119 Negative_regulation of Gene_expression of IL12A 24 0.42 17.52 5.69 91.08
75 INT225114 Localization of CNR2 3 0.60 2.25 1.7 91.00
76 INT148207 Gene_expression of CTLA4 53 0.77 29.13 12.07 90.96
77 INT15797 Positive_regulation of HLA-E 36 0.67 15.17 5.07 90.80
78 INT177954 Negative_regulation of Positive_regulation of HLA-E 2 0.07 0.61 0.33 90.80
79 INT160860 Negative_regulation of Laptm4a 1 0.34 0.54 0 90.80
80 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 90.72
81 INT80223 Positive_regulation of Hmox1 128 0.68 77.71 17.64 90.64
82 INT148461 Positive_regulation of Transcription of Hmox1 6 0.33 1.83 0.93 90.64
83 INT102634 Transcription of Hmox1 22 0.62 4.5 3.3 90.24
84 INT64743 Positive_regulation of olt 19 0.40 16.46 3.86 90.08
85 INT23148 Gene_expression of RUNX1 10 0.10 6.58 1.71 90.00
86 INT88746 Positive_regulation of Transcription of IL2 7 0.51 2.14 1.6 89.80
87 INT70860 Binding of SNRPB 17 0.35 7 1.46 89.76
88 INT5788 Gene_expression of IL2RA 60 0.75 40.67 9.98 89.48
89 INT157357 Binding of IL2RA 6 0.44 5.18 1.63 89.48
90 INT227513 Positive_regulation of Phosphorylation of Hspa9 1 0.18 1.53 0.99 89.44
91 INT51014 Transcription of IL2 42 0.71 21.56 12.7 89.20
92 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96 89.04
93 INT96147 Phosphorylation of HLA-F 1 0.48 1.22 0.08 88.64
94 INT108342 Negative_regulation of EPHB2 18 0.57 9.48 4.46 88.48
95 INT141367 Negative_regulation of Transcription of IL2 9 0.32 2.07 2.43 88.24
96 INT86805 Localization of HGF 49 0.71 28.48 6.35 88.20
97 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 88.20
98 INT168003 Localization of Fgf2 24 0.80 12.52 3.31 88.20
99 INT137609 Localization of Vegfa 22 0.78 14.67 3.01 88.20
100 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11 88.04
101 INT19620 Binding of CD86 30 0.47 12.01 9.89 88.04
102 INT132178 Binding of CD80 41 0.47 15.55 12.98 88.04
103 INT10474 Regulation of Tbce 6 0.22 4.18 5.11 87.72
104 INT320783 Binding of Flt4 2 0.26 0.98 0.05 87.36
105 INT226497 Negative_regulation of Phosphorylation of STAT4 1 0.17 1.01 0.4 87.28
106 INT146511 Gene_expression of Nrp2 25 0.78 8.67 1.55 87.20
107 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 87.20
108 INT226482 Phosphorylation of IL12A 3 0.10 1.47 0.57 86.96
109 INT155944 Gene_expression of Foxp3 66 0.66 24.37 9.12 86.60
110 INT188344 Positive_regulation of Gene_expression of Foxp3 10 0.36 5.97 2.56 86.60
111 INT226425 Phosphorylation of STAT4 1 0.25 1 0.39 86.40
112 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 86.36
113 INT81496 Gene_expression of CNR2 68 0.75 30.04 24.92 86.36
114 INT5057 Negative_regulation of Gene_expression of IFNG 23 0.58 8.33 12.3 86.36
115 INT9993 Positive_regulation of Gene_expression of IL2 131 0.69 46.27 30.04 86.24
116 INT67796 Negative_regulation of CTLA4 13 0.39 8.36 2.39 86.16
117 INT226460 Phosphorylation of TFAM 5 0.01 2.74 0.98 86.08
118 INT60779 Negative_regulation of CYP3A 63 0.59 8.38 21.27 85.88
119 INT84512 Binding of Myoz1 7 0.30 4.48 1.7 85.84
120 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 85.76
121 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 85.76
122 INT170315 Positive_regulation of Gene_expression of Ido1 50 0.67 25.39 6.06 85.56
123 INT227527 Phosphorylation of Hspa9 1 0.29 1.4 0.89 85.52
124 INT226457 Positive_regulation of Phosphorylation of TH1L 1 0.16 0.98 0.29 85.04
125 INT546 Binding of ALB 311 0.48 85.98 60.14 84.88
126 INT189240 Binding of ORM2 2 0.23 0.75 0.31 84.88
127 INT226467 Phosphorylation of TH1L 3 0.30 1.6 0.48 84.76
128 INT92524 Phosphorylation of Elk1 22 0.40 2.59 8.19 84.56
129 INT297286 Positive_regulation of Foxp3 7 0.58 3.05 0.63 84.12
130 INT11764 Positive_regulation of ENG 78 0.61 27.65 33.69 84.08
131 INT320314 Localization of SPDYE6 1 0.38 1.6 0 83.12
132 INT143357 Binding of Ros1 48 0.36 27.76 6 83.12
133 INT226435 Regulation of STAT6 4 0.37 2.98 0.34 82.96
134 INT226394 Regulation of Phosphorylation of Hand2 1 0.05 0.97 0.28 82.96
135 INT121334 Binding of HTT 11 0.47 6.66 0.78 82.84
136 INT719 Negative_regulation of SGCG 96 0.57 47.91 30.22 82.64
137 INT320020 Positive_regulation of Kcnn4 1 0.01 2.79 6.13 82.56
138 INT100692 Phosphorylation of STAT6 5 0.78 3.42 1.7 82.56
139 INT64076 Positive_regulation of Kcnma1 47 0.40 11.52 24.19 82.56
140 INT134629 Positive_regulation of Gene_expression of Flt4 3 0.32 2.13 0.52 82.56
141 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 82.52
142 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36 82.48
143 INT251 Regulation of INS 398 0.62 232.47 55.04 82.36
144 INT73504 Binding of CD28 35 0.45 15.99 10.04 82.28
145 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65 81.92
146 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25 81.92
147 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17 81.60
148 INT134628 Gene_expression of Flt4 9 0.48 7.52 1.94 81.36
149 INT347525 Positive_regulation of Nrp2 1 0.50 0.81 0.18 81.04
150 INT100861 Binding of CRP 179 0.48 175.2 26.45 81.00
151 INT220333 Binding of UROD 4 0.30 2.66 0.52 81.00
152 INT226390 Phosphorylation of Hand2 1 0.14 0.85 0.22 80.92
153 INT39413 Negative_regulation of SNRPB 7 0.31 2.57 2.36 80.72
154 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24 80.64
155 INT278154 Regulation of Syk 1 0.05 0.98 0.22 80.64
156 INT278147 Localization of Syk 1 0.30 0.98 0.22 80.64
157 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 80.60
158 INT20633 Positive_regulation of Gene_expression of LDHA 15 0.49 15.94 1.42 80.60
159 INT222906 Localization of HLA-DOA 5 0.25 2.41 0.08 80.28
160 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 80.24
161 INT175219 Binding of NUP62 31 0.27 4.51 0.53 79.92
162 INT149700 Binding of Cd86 1 0.33 0.69 0.53 79.92
163 INT278159 Regulation of LCK 1 0.04 0.98 0.22 79.92
164 INT278161 Localization of LCK 1 0.27 0.98 0.22 79.92
165 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 79.84
166 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6 79.84
167 INT127276 Gene_expression of Slurp1 12 0.59 4.99 5.73 79.64
168 INT278139 Regulation of Jak3 1 0.06 0.97 0.22 79.52
169 INT278146 Localization of Jak3 1 0.35 0.97 0.22 79.52
170 INT71370 Regulation of Ikbkb 3 0.12 1.69 1.08 79.04
171 INT278149 Localization of Ikbkb 1 0.33 0.97 0.22 79.04
172 INT320315 Protein_catabolism of BAK1 3 0.76 3.13 0.13 79.00
173 INT20721 Localization of ACOT1 47 0.80 11.37 10.95 78.88
174 INT12334 Positive_regulation of CYP3A 34 0.70 6.77 7.85 78.68
175 INT36921 Regulation of Mdk 14 0.26 6.49 5.8 78.56
176 INT41099 Localization of Mdk 5 0.64 2.38 2.89 78.56
177 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34 78.52
178 INT302039 Negative_regulation of Nrp2 6 0.51 1.65 0.19 78.48
179 INT182137 Gene_expression of TLR9 137 0.78 48.48 9.05 78.24
180 INT302043 Negative_regulation of Gene_expression of Nrp2 5 0.59 1.53 0.1 78.24
181 INT5957 Positive_regulation of Cpe 65 0.69 21.07 51.22 78.20
182 INT104481 Regulation of Mapk8 21 0.50 13.87 8.41 78.16
183 INT200900 Localization of Mapk8 9 0.40 5.76 0.84 78.16
184 INT278152 Negative_regulation of Syk 1 0.24 1.93 0.59 78.08
185 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 78.00
186 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53 78.00
187 INT347526 Regulation of Gene_expression of Nrp2 1 0.62 0.65 0.07 77.80
188 INT118906 Regulation of Mapk14 21 0.44 17.95 11.63 77.76
189 INT128587 Localization of Mapk14 15 0.81 8.41 6.1 77.76
190 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42 77.52
191 INT4679 Negative_regulation of RAPGEF5 55 0.57 47.51 4.55 77.36
192 INT11118 Gene_expression of RAPGEF5 13 0.65 9.35 0.43 77.36
193 INT161310 Negative_regulation of LCK 17 0.42 8.75 2.74 76.92
194 INT8101 Binding of INCENP 42 0.31 16.2 6.68 75.60
195 INT185754 Negative_regulation of Binding of INCENP 5 0.03 2.01 0.13 75.60
196 INT190676 Binding of Fkbp1a 15 0.36 3.11 0.28 75.40
197 INT60575 Binding of Fkbp1a 9 0.26 2.09 4.46 75.40
198 INT273505 Negative_regulation of GBP4 1 0.14 0.32 0 75.40
199 INT15796 Regulation of IL2 66 0.61 25.43 20.62 75.00
200 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 75.00
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