D:Osteoarthropathy

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pChart

Disease Term
Synonyms Currarino Syndrome, Hoa, Hypertrophic Osteoarthropathies Primary, Hypertrophic Osteoarthropathy, HYPERTROPHIC OSTEOARTHROPATHY PRIMARY, Hypertrophic Pulmonary Osteoarthropathy, OSTEOARTHROPATHIES PRIMARY HYPERTROPHIC, Osteoarthropathy Primary Hypertrophic, Pachydermoperiostoses, Pachydermoperiostosis, PACHYDERMOPERIOSTOSIS SYNDROME
Documents 138
Hot Single Events 29
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Osteoarthropathy. They are ordered first by their relevance to Osteoarthropathy and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT248310 Crx Regulation of MATN3 1 0.07 0.65 0.45 100.00
2 INT353646 Binding of NPL and H58 1 0.01 0.26 0 5.00
3 INT353647 Binding of CD82 and H58 1 0.05 0.86 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Osteoarthropathy. They are ordered first by their pain relevance and then by number of times they were reported in Osteoarthropathy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT59900 Binding of MATN3 13 0.42 17.19 3.59 100.00
2 INT135879 Localization of MATN3 12 0.80 10.31 1.44 100.00
3 INT59899 Regulation of MATN3 4 0.45 7.61 1.6 100.00
4 INT169023 Positive_regulation of MATN3 2 0.43 3.67 1.23 100.00
5 INT131844 Gene_expression of MATN3 12 0.78 9.65 0.92 100.00
6 INT39959 Negative_regulation of GFER 3 0.42 1.4 0.19 100.00
7 INT39958 Positive_regulation of GFER 1 0.49 0.7 0.1 100.00
8 INT248309 Positive_regulation of Binding of MATN3 1 0.08 1.81 1.11 100.00
9 INT108798 Negative_regulation of Positive_regulation of ALPP 9 0.25 4.26 1.46 100.00
10 INT248308 Regulation of Localization of MATN3 2 0.27 2.48 0.71 100.00
11 INT249 Localization of GHRH 215 0.80 78.02 51.87 99.08
12 INT353638 Localization of H52 1 0.05 1.08 0.15 98.80
13 INT353640 Localization of H50 1 0.04 1.07 0.15 98.80
14 INT4535 Localization of PROC 106 0.73 76.24 21.1 98.70
15 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 98.48
16 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 98.22
17 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5 94.96
18 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59 94.96
19 INT148703 Gene_expression of NOVA2 73 0.65 18.05 8.3 94.28
20 INT245577 Localization of SFTPD 7 0.63 10.43 1.84 93.12
21 INT34778 Localization of IGF2 5 0.62 4.78 0.59 92.76
22 INT2673 Negative_regulation of PROC 93 0.57 50.34 12.79 92.08
23 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 90.88
24 INT4378 Regulation of Gene_expression of GH1 26 0.47 10.2 4.61 90.88
25 INT214 Localization of AVP 370 0.81 208.51 91.09 90.12
26 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 86.08
27 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 86.08
28 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9 84.04
29 INT148 Positive_regulation of Gnrhr 182 0.70 47.44 79.64 81.44
30 INT248307 Negative_regulation of Crx 1 0.33 1.13 0.64 79.04
31 INT353639 Gene_expression of H58 1 0.08 1.37 0.06 76.56
32 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 75.00
33 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 75.00
34 INT158796 Positive_regulation of SMUG1 67 0.70 38.97 8.98 75.00
35 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 74.68
36 INT248303 Gene_expression of Crx 1 0.61 2.06 1.04 57.24
37 INT83646 Binding of Il1rn 12 0.37 4.41 3.51 50.28
38 INT85492 Localization of IL1R1 6 0.72 2.44 1.85 50.28
39 INT131928 Localization of Il1rn 3 0.74 2.22 2.24 49.68
40 INT248306 Positive_regulation of Gene_expression of Crx 1 0.39 0.88 0.44 40.88
41 INT248305 Regulation of Crx 1 0.21 0.74 0.31 31.96
42 INT8484 Localization of Nr3c1 8 0.53 3.12 2.32 29.92
43 INT248304 Positive_regulation of Localization of Nr3c1 2 0.10 1.39 0.87 29.92
44 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 6.44
45 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 5.00
46 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
47 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 5.00
48 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67 5.00
49 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
50 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 5.00
51 INT4877 Gene_expression of MME 184 0.78 122.82 24.78 5.00
52 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89 5.00
53 INT91817 Positive_regulation of RETNLB 22 0.34 21.4 13.12 5.00
54 INT78515 Negative_regulation of Mag 10 0.54 9.4 5.06 5.00
55 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 5.00
56 INT569 Negative_regulation of C4a 13 0.42 9.48 2.85 5.00
57 INT39180 Gene_expression of NPL 7 0.38 3.61 2.48 5.00
58 INT126457 Gene_expression of BCL6 34 0.66 22.45 1.75 5.00
59 INT294726 Positive_regulation of Lts1 5 0.49 4.06 0.87 5.00
60 INT353637 Binding of H58 1 0.05 0.82 0.18 5.00
61 INT210578 Gene_expression of PAX5 5 0.44 3.46 0.12 5.00
62 INT252156 Gene_expression of MUM1 1 0.32 2.22 0.12 5.00
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