D:Osteomyelitis

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Disease Term
Synonyms Osteomyelitides, Osteomyelitis Disease, OSTEOMYELITIS DISORDER, OSTEOMYELITIS DYSFUNCTION, Osteomyelitis Syndrome
Documents 1568
Hot Single Events 106
Hot Interactions 11

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Osteomyelitis. They are ordered first by their relevance to Osteomyelitis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT274569 Binding of PSTPIP2 and PSTPIP1 1 0.50 2.07 0.31 95.80
2 INT229785 Binding of RAB7A and SPTLC1 1 0.40 1.5 0.27 90.72
3 INT274578 Binding of ABL1 and PSTPIP1 1 0.07 1.55 0.21 89.60
4 INT274583 Binding of ABL1 and PSTPIP2 1 0.06 0.79 0.11 88.92
5 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91 85.04
6 INT188805 TNF Positive_regulation of Gene_expression of Crp 1 0.15 2.96 0.95 85.04
7 INT188803 Il1 Positive_regulation of Gene_expression of Crp 1 0.03 2.95 0.94 85.04
8 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 83.72
9 INT197051 Binding of HLA-E and ATP8A1 1 0.00 6.52 1.14 81.56
10 INT317832 Binding of Mefv and Il1 1 0.03 3.89 0.7 80.80
11 INT317834 Binding of Pstpip1 and Il1 1 0.00 2.03 0.48 80.80
12 INT278379 Binding of Pstpip1 and Mefv 3 0.03 2.02 0.48 79.28
13 INT120870 Binding of Wnk1 and Sptlc1 1 0.14 1.24 0.56 79.20
14 INT150392 Binding of MEFV and PSTPIP1 2 0.51 10.49 1.44 70.96
15 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 65.48
16 INT272024 Gene_expression of GOPC Positive_regulation of Localization of COL7A1 1 0.10 0.86 0.14 52.56
17 INT342887 Binding of IFNG and IFNGR1 1 0.02 0.65 0.05 50.00
18 INT342886 Binding of C3 and CD40 1 0.02 0.66 0.05 50.00
19 INT206088 IL6 Positive_regulation of JAK1 1 0.18 0.05 0 47.04
20 INT317833 Nlrp3 Positive_regulation of Localization of Il1 1 0.06 1.38 0.26 19.32
21 INT197050 Binding of HLA-DOA and HLA-E 2 0.08 1.73 0.58 7.92
22 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11 5.00
23 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
24 INT306745 Binding of Il12a and IL23A 1 0.10 3.25 1.56 5.00
25 INT341336 Binding of Pepd and Nav1 1 0.07 0.92 1.3 5.00
26 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18 5.00
27 INT230019 Binding of HLA-B and ERAL1 1 0.00 2.23 1.1 5.00
28 INT317836 Binding of Fibp and Pycard 1 0.00 2.68 0.98 5.00
29 INT107910 Binding of Tnfrsf11b and Tnfsf11 6 0.30 5.88 0.7 5.00
30 INT110835 Binding of SPTLC2 and SPTLC1 2 0.42 1.36 0.68 5.00
31 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63 5.00
32 INT333476 IL12B Positive_regulation of Localization of AFP 1 0.03 0.26 0.57 5.00
33 INT333477 CXCL10 Positive_regulation of TH1L 1 0.14 0.32 0.56 5.00
34 INT150391 Binding of MEFV and PYCARD 4 0.14 3 0.48 5.00
35 INT115186 IL6 Positive_regulation of Phosphorylation of STAT3 2 0.19 0.35 0.48 5.00
36 INT306732 Il17a Positive_regulation of Gene_expression of Il2 1 0.09 1.07 0.46 5.00
37 INT306731 Il22 Positive_regulation of Gene_expression of Il2 1 0.12 1.07 0.46 5.00
38 INT150393 Binding of CASP1 and MEFV 2 0.16 2.48 0.45 5.00
39 INT172125 Binding of Tnfrsf11b and Tnfrsf11a 2 0.17 2.12 0.39 5.00
40 INT110834 Binding of AGXT and SPTLC2 2 0.27 0.71 0.36 5.00
41 INT188804 S100a8 Positive_regulation of Gene_expression of Tnfsf11 1 0.00 0.7 0.31 5.00
42 INT317835 Nlrp3 Positive_regulation of Il18 1 0.08 1.49 0.31 5.00
43 INT334879 CASP1 Regulation of IL1B 1 0.03 1.63 0.31 5.00
44 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27 5.00
45 INT188802 Il1 Negative_regulation of Gene_expression of Col7a1 1 0.00 0.71 0.26 5.00
46 INT258398 Binding of IL6R and JAK1 1 0.01 0.75 0.23 5.00
47 INT274584 Binding of PSTPIP1 and PYCARD 1 0.13 1.34 0.22 5.00
48 INT306714 IL23A Positive_regulation of TNF 1 0.29 0.5 0.21 5.00
49 INT188801 Il6 Positive_regulation of Positive_regulation of Tnfsf11 1 0.06 0.46 0.21 5.00
50 INT306746 Il12a Positive_regulation of TNF 1 0.24 0.5 0.21 5.00
51 INT317831 Binding of Mefv and Nlrx1 1 0.00 1.77 0.2 5.00
52 INT306744 IL23A Positive_regulation of Il12a 1 0.13 0.59 0.2 5.00
53 INT206089 Negative_regulation of FOSB Negative_regulation of Gene_expression of PTGS2 1 0.00 0.97 0.19 5.00
54 INT258399 Binding of IL6R and IL6ST 1 0.06 0.61 0.18 5.00
55 INT252646 Binding of C6orf25 and SYT16 1 0.00 0.51 0.17 5.00
56 INT206081 IL6ST Negative_regulation of IL6 1 0.11 0.81 0.17 5.00
57 INT206059 IL6 Positive_regulation of INS 1 0.02 1.16 0.16 5.00
58 INT306747 IL23A Positive_regulation of Il17a 1 0.05 0.51 0.16 5.00
59 INT206070 ANG Positive_regulation of Transcription of IL6 1 0.05 1.5 0.15 5.00
60 INT274568 Binding of MEFV and PSTPIP2 1 0.45 0.61 0.13 5.00
61 INT206065 EDN1 Positive_regulation of IL6 1 0.03 0.47 0.12 5.00
62 INT206056 PTK2B Negative_regulation of Positive_regulation of IRF6 1 0.00 0.66 0.1 5.00
63 INT206042 Negative_regulation of FDPS Negative_regulation of Binding of FDPS and GGPS1 1 0.00 0 0.09 5.00
64 INT206054 RAC1 Positive_regulation of STAT3 1 0.07 0.11 0.09 5.00
65 INT206075 Negative_regulation of FDPS Negative_regulation of Binding of GGPS1 1 0.01 0 0.09 5.00
66 INT206078 Binding of FDPS and GGPS1 1 0.00 0 0.09 5.00
67 INT206072 ANG Positive_regulation of IL6 1 0.05 0.5 0.08 5.00
68 INT206080 ANG Regulation of Gene_expression of IL6 1 0.03 0.4 0.07 5.00
69 INT206063 ANG Positive_regulation of Gene_expression of KRT20 1 0.00 1.01 0.07 5.00
70 INT206087 RAC1 Positive_regulation of Gene_expression of STAT3 1 0.08 0.05 0.05 5.00
71 INT203638 Binding of MR1 and GOPC 1 0.04 1.43 0.05 5.00
72 INT274553 MEFV Positive_regulation of Binding of PSTPIP1 and PYCARD 1 0.13 0.19 0.05 5.00
73 INT191590 Binding of AMBP and Arsb 1 0.00 1.82 0.04 5.00
74 INT274574 MEFV Regulation of Localization of PSTPIP1 1 0.48 0.17 0.04 5.00
75 INT206083 LDLR Positive_regulation of Binding of STAT3 1 0.02 0.53 0.04 5.00
76 INT206073 Negative_regulation of RAC1 Positive_regulation of IL6 1 0.14 0.06 0.04 5.00
77 INT274567 Positive_regulation of Binding of MEFV and PSTPIP1 1 0.46 0.22 0.04 5.00
78 INT274587 Binding of PSTPIP1 and BFAR 1 0.17 0.08 0.04 5.00
79 INT274585 Binding of PSTPIP1 and TRIP10 1 0.15 0.08 0.04 5.00
80 INT206067 Gene_expression of RAC1 Positive_regulation of Positive_regulation of IL6 1 0.16 0.07 0.04 5.00
81 INT274577 Binding of MEFV and SASH3 1 0.01 0.45 0.04 5.00
82 INT274589 Binding of MEFV and Regulation of Localization of PSTPIP1 1 0.48 0.17 0.04 5.00
83 INT206068 RAC1 Positive_regulation of IL6 1 0.16 0.06 0.04 5.00
84 INT206066 LDLR Positive_regulation of Phosphorylation of STAT3 1 0.02 0.52 0.04 5.00
85 INT206071 IRF6 Positive_regulation of Positive_regulation of IL1B 1 0.00 0.58 0.03 5.00
86 INT264148 Binding of CLCN7 and Ostm1 1 0.17 0.72 0.03 5.00
87 INT206076 IL6 Positive_regulation of Positive_regulation of STAT3 1 0.19 0.3 0.03 5.00
88 INT206061 RAC1 Positive_regulation of Positive_regulation of STAT3 1 0.07 0.43 0.03 5.00
89 INT274588 Binding of PSTPIP1 and Positive_regulation of MEFV 1 0.46 0.05 0.03 5.00
90 INT274573 Positive_regulation of Binding of MEFV and PYCARD 1 0.09 0.06 0.03 5.00
91 INT274575 MEFV Regulation of PSTPIP1 1 0.42 0.2 0.03 5.00
92 INT274552 PSTPIP1 Positive_regulation of Binding of PSTPIP1 and PYCARD 1 0.13 0.06 0.03 5.00
93 INT274591 Binding of PSTPIP1 and SASH3 1 0.01 0 0 5.00
94 INT206085 FDPS Positive_regulation of AGFG1 1 0.00 0.4 0 5.00
95 INT206058 EGFR Negative_regulation of Gene_expression of IL6 1 0.07 0.62 0 5.00
96 INT206079 ANG Regulation of KRT20 1 0.00 0.54 0 5.00
97 INT325904 Binding of F2 and Wbp5 1 0.01 1.22 0 5.00
98 INT325898 Negative_regulation of Binding of F2 and Gopc 1 0.03 0.14 0 5.00
99 INT206069 ANG Positive_regulation of Gene_expression of IL6 1 0.05 0.51 0 5.00
100 INT249151 Binding of Cfl1 and Was 1 0.01 0.18 0 5.00
101 INT325910 Wbp5 Positive_regulation of Positive_regulation of F2 1 0.01 0.67 0 5.00
102 INT325900 Binding of Dio1 and Wbp5 1 0.00 0.25 0 5.00
103 INT264143 TCIRG1 Regulation of BSND 1 0.02 0.74 0 5.00
104 INT325902 Binding of F2 and Fgg 1 0.01 0 0 5.00
105 INT206178 Foxm1 Positive_regulation of Protein_catabolism of Olr1 1 0.00 0.47 0 5.00
106 INT206086 LDLR Positive_regulation of Localization of IL6 1 0.03 0.42 0 5.00
107 INT206060 FDPS Positive_regulation of AKT1 1 0.00 0.4 0 5.00
108 INT206055 F2 Positive_regulation of Gene_expression of IL6 1 0.01 1.24 0 5.00
109 INT249148 Binding of Was and Racgap1 1 0.03 0.18 0 5.00
110 INT206082 IL6 Positive_regulation of Gene_expression of CCL2 1 0.07 0.3 0 5.00
111 INT325908 Binding of Wbp5 and Fgg 1 0.00 1.2 0 5.00
112 INT264144 CLCN7 Regulation of ADO 1 0.04 0.71 0 5.00
113 INT206180 Foxm1 Positive_regulation of Transcription of Olr1 1 0.00 0.48 0 5.00
114 INT325903 Binding of F2 and Gopc 1 0.02 0.26 0 5.00
115 INT249149 Binding of Cdc42 and Was 1 0.08 0.18 0 5.00
116 INT325901 Binding of Dio1 and F2 1 0.01 0.63 0 5.00
117 INT274623 Binding of TRIP10 and Amph 1 0.17 0 0 5.00
118 INT206077 RAC1 Positive_regulation of Phosphorylation of STAT3 1 0.07 0.35 0 5.00
119 INT325897 Negative_regulation of Binding of F2 and Wbp5 1 0.01 0.96 0 5.00
120 INT274586 Binding of TRIP10 and BFAR 1 0.06 0 0 5.00
121 INT274570 Binding of MEFV and Regulation of BFAR 1 0.09 0.05 0 5.00
122 INT281990 Binding of ALPP and Ik 1 0.02 0.29 0 5.00
123 INT206181 FDPS Positive_regulation of ras 1 0.00 0.4 0 5.00
124 INT274576 MEFV Positive_regulation of PSTPIP1 1 0.46 0 0 5.00
125 INT325905 Wbp5 Positive_regulation of F2 1 0.01 0.37 0 5.00
126 INT274590 Positive_regulation of Binding of MEFV and SASH3 1 0.01 0.27 0 5.00
127 INT325906 Binding of Hps3 and Fgg 1 0.02 0.96 0 5.00
128 INT249364 Binding of PCS and Alb 1 0.00 0.75 0 5.00
129 INT325899 Binding of Hps3 and F2 1 0.12 2.43 0 5.00
130 INT274622 Binding of CLIP1 and Amph 1 0.40 0 0 5.00
131 INT274581 Binding of CLIP1 and BFAR 1 0.15 0 0 5.00
132 INT206084 EGF Negative_regulation of Gene_expression of IL6 1 0.05 0.61 0 5.00
133 INT325907 Positive_regulation of Binding of F2 and Gopc 1 0.03 0.12 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Osteomyelitis. They are ordered first by their pain relevance and then by number of times they were reported in Osteomyelitis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT202701 Regulation of CNO 1 0.27 1.26 0.21 100.00
2 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 99.88
3 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 99.52
4 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 99.48
5 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07 99.48
6 INT92822 Negative_regulation of Gene_expression of Crp 36 0.49 29.5 8.83 99.48
7 INT183910 Negative_regulation of Gene_expression of Lbp 10 0.35 9.78 6.15 99.48
8 INT206737 Negative_regulation of Gene_expression of HMGB1 3 0.32 3.48 0.09 99.48
9 INT55647 Binding of Nfasc 5 0.35 5.43 0.94 99.32
10 INT331114 Gene_expression of DURS1 2 0.49 3.93 0.45 99.32
11 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 99.28
12 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15 99.28
13 INT20280 Positive_regulation of Esr1 32 0.69 18.37 5.69 99.28
14 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52 99.04
15 INT18925 Gene_expression of Paics 3 0.52 1.25 0.93 99.04
16 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 99.04
17 INT31541 Regulation of Esr1 15 0.54 4.12 2.82 99.00
18 INT2429 Negative_regulation of Mpo 128 0.59 93.76 39.57 99.00
19 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 98.90
20 INT184269 Gene_expression of HMGB1 51 0.77 42.96 4.55 98.88
21 INT1027 Gene_expression of Lbp 132 0.77 106.7 54.16 98.88
22 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 98.88
23 INT131916 Negative_regulation of ALPL 10 0.42 9.33 1.8 98.80
24 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 98.76
25 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 98.76
26 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 98.76
27 INT253882 Positive_regulation of Localization of Esr1 1 0.30 1.21 0.06 98.54
28 INT8511 Localization of Esr1 6 0.80 3.27 1.26 98.54
29 INT9089 Positive_regulation of Ceacam1 17 0.69 7.09 2.49 98.32
30 INT217429 Positive_regulation of SLC9A6 22 0.38 42.17 0.67 98.18
31 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 98.12
32 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 97.96
33 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 97.64
34 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 97.32
35 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 97.28
36 INT197194 Binding of DURS1 3 0.27 4.2 0.33 97.28
37 INT105466 Binding of HM13 1 0.36 1.13 0.09 97.22
38 INT118124 Binding of USE1 24 0.16 16.64 5.44 97.20
39 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 96.84
40 INT70265 Regulation of MRI1 42 0.39 30.95 14.18 96.76
41 INT298429 Gene_expression of CCL22 3 0.32 2.08 0.74 96.48
42 INT319438 Binding of CCL22 2 0.22 2.2 0.37 96.48
43 INT49238 Protein_catabolism of COL1A2 30 0.97 15.64 3.45 96.48
44 INT8799 Negative_regulation of Csrp1 24 0.58 11.01 6.86 96.24
45 INT16150 Positive_regulation of NKG7 10 0.69 10.26 1.73 96.00
46 INT20129 Regulation of Il1 53 0.53 44.14 19.89 95.76
47 INT6848 Gene_expression of BDKRB2 40 0.75 17.19 20.04 95.72
48 INT6850 Gene_expression of SPANXB1 34 0.46 15.91 16.38 95.72
49 INT100399 Gene_expression of CCL17 22 0.77 9.38 2.43 95.68
50 INT322377 Binding of CCL17 1 0.17 1.13 0.12 95.68
51 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 95.64
52 INT209355 Binding of SLC9A6 8 0.42 14.9 0.09 95.36
53 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09 95.12
54 INT194661 Binding of CCL5 9 0.46 6.07 2.73 95.12
55 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37 95.04
56 INT252662 Binding of SYT16 1 0.01 8.05 0.45 94.88
57 INT81955 Positive_regulation of SPTLC1 12 0.70 10.25 3.12 94.88
58 INT273531 Gene_expression of BRON-J 1 0.31 5.53 0.75 94.64
59 INT273532 Regulation of Gene_expression of BRON-J 1 0.21 0.77 0.15 94.64
60 INT28872 Positive_regulation of CSRP1 49 0.70 47.23 11.7 94.16
61 INT8798 Positive_regulation of Csrp1 61 0.69 63.86 14.14 93.92
62 INT117081 Positive_regulation of Localization of Csrp1 2 0.28 2.43 1.35 93.92
63 INT7253 Negative_regulation of Localization of Gast 70 0.59 21.06 20.06 93.64
64 INT250 Regulation of GHRH 65 0.61 17.46 23.19 93.60
65 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 93.56
66 INT117080 Localization of Csrp1 6 0.42 7.23 3.09 93.40
67 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 93.16
68 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 93.16
69 INT6810 Gene_expression of ENO2 70 0.78 54.8 8.35 93.16
70 INT90 Localization of Gast 400 0.81 137.67 113 93.12
71 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 92.56
72 INT177584 Gene_expression of MR1 80 0.58 46.48 5.48 92.00
73 INT178834 Localization of MR1 8 0.21 6.52 0.48 92.00
74 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 91.76
75 INT63550 Positive_regulation of Protein_catabolism of COL1A2 4 0.25 3.22 0.38 91.56
76 INT2093 Gene_expression of GAST 50 0.78 32.32 7.98 90.00
77 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 89.36
78 INT147823 Localization of H1fnt 3 0.35 2.35 0.41 89.28
79 INT35009 Binding of CSAD 12 0.41 10.74 3.21 89.08
80 INT1155 Binding of GAST 12 0.36 3.64 3.5 89.04
81 INT274612 Phosphorylation of KPTN 1 0.02 1.25 0.18 88.96
82 INT76227 Binding of NPC1 30 0.41 32.31 4.05 88.24
83 INT74520 Positive_regulation of CD68 30 0.61 31.68 7.59 88.08
84 INT39413 Negative_regulation of SNRPB 7 0.31 2.57 2.36 87.96
85 INT615 Regulation of Alb 66 0.62 33.43 15.33 87.68
86 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 87.56
87 INT43997 Positive_regulation of Gene_expression of Esr1 57 0.51 36.66 5.51 87.56
88 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 87.52
89 INT19775 Localization of Il1 183 0.78 145.5 50.91 87.52
90 INT62400 Positive_regulation of Localization of Il1 34 0.67 35.53 7.96 87.52
91 INT34590 Gene_expression of ALPP 199 0.75 89.85 15.1 87.40
92 INT186480 Positive_regulation of Transcription of F8 1 0.06 2.08 0.4 87.28
93 INT60115 Transcription of F8 2 0.08 3.05 0.58 86.88
94 INT12339 Localization of IL8 437 0.81 251.87 117.39 86.64
95 INT86705 Gene_expression of BTG3 41 0.65 37.29 8.29 85.84
96 INT9995 Localization of C6orf25 13 0.69 6.48 2.29 85.60
97 INT4075 Positive_regulation of Gene_expression of Gast 24 0.68 19.99 4.02 85.56
98 INT186482 Regulation of Transcription of ANGPTL5 1 0.03 2.05 0.4 85.56
99 INT30 Gene_expression of Gast 158 0.78 99 41.45 85.20
100 INT186481 Transcription of ANGPTL5 1 0.04 2.04 0.39 85.16
101 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 84.80
102 INT24453 Binding of NLRP3 18 0.48 13.7 1.93 83.28
103 INT282226 Negative_regulation of Ptpro 1 0.03 1.02 0 83.20
104 INT16997 Binding of PRTN3 34 0.48 33.44 6.45 81.68
105 INT11699 Binding of HLA-E 85 0.47 52.51 13.41 81.56
106 INT2065 Binding of BTG3 15 0.36 10.9 4.65 81.20
107 INT209354 Gene_expression of SLC9A6 15 0.58 37.52 0.29 79.60
108 INT257837 Positive_regulation of Negative_regulation of BTK 1 0.08 2.01 0.17 78.92
109 INT105131 Gene_expression of KRT122P 8 0.58 9.1 0.7 78.56
110 INT216291 Negative_regulation of BTK 4 0.42 4.9 0.67 78.00
111 INT175263 Gene_expression of Ptpro 2 0.65 0.94 0 77.40
112 INT258932 Positive_regulation of TBX1 3 0.39 2.73 0.82 76.48
113 INT218795 Regulation of VCF 2 0.43 1.49 0.33 76.36
114 INT14572 Binding of INS 205 0.48 175.43 13.38 75.84
115 INT16130 Binding of IGF1 67 0.48 27.43 2.95 75.84
116 INT202702 Binding of IGF2BP3 2 0.36 3.82 0.08 75.84
117 INT221874 Binding of Ctrcts 3 0.00 1.29 0.71 75.84
118 INT128699 Regulation of Il12a 3 0.45 3.36 1.59 75.00
119 INT67589 Gene_expression of MT1E 8 0.51 7.52 1.09 75.00
120 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 75.00
121 INT2038 Localization of Esr1 104 0.79 40.12 13.27 75.00
122 INT10094 Negative_regulation of ALPP 36 0.37 20.45 6.45 75.00
123 INT110210 Negative_regulation of CSRP1 12 0.59 8.96 2.81 75.00
124 INT85878 Negative_regulation of Il12a 4 0.58 2.88 2.21 75.00
125 INT156544 Regulation of Il12b 2 0.44 1.29 0.66 75.00
126 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 74.52
127 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 74.08
128 INT132850 Positive_regulation of Ptpro 2 0.03 0.99 1.02 73.76
129 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99 73.52
130 INT65489 Regulation of Gene_expression of Crp 28 0.59 29.17 7.56 73.52
131 INT11101 Regulation of Gene_expression of Lbp 6 0.61 5.43 3.49 73.52
132 INT299470 Regulation of Gene_expression of HMGB1 1 0.18 1.58 0 73.52
133 INT28312 Gene_expression of ABCA1 85 0.72 37.69 9.27 73.12
134 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 72.20
135 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 70.68
136 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52 68.32
137 INT299469 Regulation of HMGB1 2 0.18 2.27 0.03 68.16
138 INT38971 Positive_regulation of Gene_expression of Gtf3a 27 0.60 18.25 7.77 66.04
139 INT98068 Gene_expression of SCN2A 19 0.75 14.42 3.31 65.92
140 INT304592 Regulation of Spir1 1 0.04 0.94 0.03 65.92
141 INT86437 Binding of IL6 154 0.48 121.22 29.3 65.48
142 INT74145 Localization of CPQ 2 0.68 1.7 1.01 65.44
143 INT56985 Gene_expression of MEFV 56 0.71 46.71 9.47 65.40
144 INT4345 Gene_expression of Gtf3a 157 0.67 80.75 48.47 65.36
145 INT94827 Gene_expression of HBS1L 24 0.67 26.11 1.61 64.72
146 INT32165 Binding of CALM1 92 0.48 24.19 29.57 64.48
147 INT27534 Negative_regulation of Gba 10 0.57 6.23 0.38 64.08
148 INT133422 Binding of IL6ST 10 0.40 4.9 1.49 63.88
149 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 61.20
150 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 61.20
151 INT61171 Gene_expression of S100A8 92 0.76 57.74 9.98 61.00
152 INT94042 Positive_regulation of Gene_expression of S100A8 15 0.67 13.52 2.44 61.00
153 INT72455 Transcription of S100A8 3 0.69 1.66 0.36 61.00
154 INT334889 Positive_regulation of Transcription of MRPL14 1 0.07 0.79 0.21 61.00
155 INT334883 Positive_regulation of Transcription of CBFA2T2 1 0.03 0.79 0.21 61.00
156 INT334884 Transcription of CBFA2T2 1 0.04 0.78 0.21 61.00
157 INT334887 Positive_regulation of Gene_expression of CBFA2T2 1 0.03 0.79 0.21 61.00
158 INT334888 Gene_expression of CBFA2T2 1 0.05 0.78 0.21 61.00
159 INT334885 Transcription of MRPL14 1 0.10 0.79 0.21 61.00
160 INT334886 Gene_expression of MRPL14 1 0.11 0.79 0.21 61.00
161 INT334890 Positive_regulation of Gene_expression of MRPL14 1 0.07 0.79 0.21 61.00
162 INT334891 Positive_regulation of Transcription of S100A8 1 0.06 0.79 0.21 61.00
163 INT31 Negative_regulation of Gene_expression of Gast 10 0.42 5.3 3.34 59.84
164 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 59.56
165 INT7678 Localization of Alb 142 0.81 80.93 22.49 58.76
166 INT19511 Localization of Il6 212 0.81 118.17 67.67 58.52
167 INT1030 Localization of Lbp 52 0.74 38.92 24.91 58.52
168 INT38056 Localization of Crp 71 0.78 53.14 17.03 58.52
169 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76 58.52
170 INT184288 Localization of HMGB1 20 0.61 14.5 3.84 58.52
171 INT133733 Positive_regulation of Localization of Lbp 6 0.43 9.19 3.61 58.52
172 INT219168 Positive_regulation of Localization of HMGB1 5 0.36 4 1.16 58.52
173 INT157115 Positive_regulation of Localization of Crp 4 0.59 1.96 0.88 58.52
174 INT206143 Positive_regulation of Transcription of STAT3 1 0.21 0.34 0.06 55.52
175 INT206148 Positive_regulation of Transcription of STAT1 2 0.21 0.72 0.06 55.52
176 INT128424 Transcription of STAT1 5 0.37 3.28 0.9 54.96
177 INT144038 Transcription of STAT3 4 0.56 0.99 0.25 54.96
178 INT218794 Protein_catabolism of VCF 1 0.53 0.91 0.14 54.80
179 INT62688 Binding of Wnk1 2 0.17 2.83 0.63 54.24
180 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 54.20
181 INT139780 Binding of AQP1 7 0.32 4.62 0.54 51.72
182 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 51.68
183 INT213409 Gene_expression of TK2 1 0.25 2.95 0.5 51.32
184 INT4228 Gene_expression of CAT 50 0.75 20.62 7.18 51.12
185 INT213411 Positive_regulation of TK2 1 0.21 2.95 0.5 50.88
186 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 50.00
187 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 50.00
188 INT756 Gene_expression of C3 138 0.75 100.6 19.2 50.00
189 INT80755 Gene_expression of CD40 88 0.75 53.68 17.86 50.00
190 INT8632 Regulation of Nfasc 15 0.54 2.87 9.08 50.00
191 INT342889 Gene_expression of IFNGR1 1 0.28 0.65 0.05 50.00
192 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 49.00
193 INT91100 Binding of SPTLC1 10 0.47 12.85 5.71 48.72
194 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 48.32
195 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 48.32
196 INT2144 Localization of COL7A1 36 0.74 20.92 4.67 47.92
197 INT38671 Positive_regulation of KRT20 62 0.53 40.17 5.6 46.80
198 INT56491 Positive_regulation of Tnfrsf8 4 0.12 3.38 0.59 46.80
199 INT118035 Positive_regulation of JAK1 23 0.67 10.57 3.29 46.08
200 INT206156 Positive_regulation of Phosphorylation of IL6ST 1 0.14 0.05 0 46.08
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