D:Ovarian Cysts

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Disease Term
Synonyms BENIGN OVARIAN CYST, Corpus Luteum Cyst, Corpus Luteum Cysts, COVARIAN CYST BENIGN, Cyst Corpus Luteum, CYST OF OVARY, CYST OVARIAN, Cysts Corpus Luteum, Cysts Ovarian, OVARIAN CYST, OVARIAN CYST BENIGN
Documents 293
Hot Single Events 67
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Ovarian Cysts. They are ordered first by their relevance to Ovarian Cysts and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT206824 Binding of Muc5b and Gopc 1 0.07 0.05 0 46.76
2 INT206825 Binding of Muc2 and Gopc 1 0.08 0.05 0 46.76
3 INT256632 Binding of PTCH1 and Jkamp 1 0.00 2.32 0 15.12
4 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
5 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
6 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12 5.00
7 INT257745 SAGE1 Positive_regulation of AXL 1 0.07 1.96 0.69 5.00
8 INT257738 PIK3CA Regulation of Localization of ACTN4 1 0.16 1.03 0.39 5.00
9 INT173704 Binding of PCOS1 and Edn1 1 0.01 0.99 0.37 5.00
10 INT296304 Binding of SPIN1 and ENDO1 1 0.03 1.7 0.37 5.00
11 INT296306 Binding of BGLAP and SPIN1 1 0.05 1.69 0.37 5.00
12 INT257741 HRAS Negative_regulation of PTEN 1 0.15 1.06 0.35 5.00
13 INT257737 Positive_regulation of HRAS Negative_regulation of PTEN 1 0.17 1.07 0.35 5.00
14 INT257746 SHC1 Positive_regulation of Positive_regulation of PIK3CA 1 0.26 1.04 0.34 5.00
15 INT257743 Binding of PIK3CA and SHC1 1 0.21 1.03 0.31 5.00
16 INT257735 GAS6 Positive_regulation of Gene_expression of SAGE1 1 0.04 0.98 0.31 5.00
17 INT257739 SAGE1 Positive_regulation of DDR1 1 0.00 0.91 0.31 5.00
18 INT257744 Binding of PIK3R2 and SHC1 1 0.08 0.96 0.28 5.00
19 INT257740 SAGE1 Positive_regulation of Gene_expression of AXL 1 0.07 0.72 0.27 5.00
20 INT295430 BRD2 Positive_regulation of PLOD1 1 0.02 0.33 0.22 5.00
21 INT295434 BRD2 Positive_regulation of Gene_expression of GNRH1 1 0.02 0.07 0.2 5.00
22 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19 5.00
23 INT65677 Binding of CGA and FSHR 2 0.25 0.29 0.16 5.00
24 INT295433 Binding of PLOD1 and SCN5A 1 0.07 0.25 0.16 5.00
25 INT65676 Binding of CGA and PLOD1 3 0.23 1.68 0.1 5.00
26 INT254641 CGA Positive_regulation of AGT 1 0.17 1.51 0.08 5.00
27 INT254640 CGA Positive_regulation of REN 1 0.07 1.51 0.08 5.00
28 INT254639 CGA Positive_regulation of Gene_expression of AGT 1 0.18 1.51 0.08 5.00
29 INT308432 Binding of PDE4A and Aip 1 0.05 3.1 0.05 5.00
30 INT308425 Binding of Pde2a and Aip 1 0.04 1.37 0 5.00
31 INT324053 Binding of Banf1 and Lemd3 1 0.20 0.15 0 5.00
32 INT227399 Binding of D5Mit424 and Alms1 1 0.01 0.71 0 5.00
33 INT295432 FSHR Positive_regulation of PCOS1 1 0.06 1.24 0 5.00
34 INT295431 FSHR Positive_regulation of CGA 1 0.29 0.27 0 5.00
35 INT308426 Binding of Pde4a and Aip 1 0.02 0.89 0 5.00
36 INT227398 Binding of H2afy and Alms1 1 0.01 1.42 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Ovarian Cysts. They are ordered first by their pain relevance and then by number of times they were reported in Ovarian Cysts. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT11506 Binding of MUC16 20 0.48 22.89 1.03 99.92
2 INT64223 Regulation of Xpnpep1 3 0.27 3.13 0.68 99.46
3 INT318001 Gene_expression of Nobox 1 0.48 1.03 0 99.20
4 INT3104 Negative_regulation of CGA 76 0.54 29.81 12.23 98.48
5 INT10070 Negative_regulation of Fshb 13 0.42 3.48 2.5 98.48
6 INT318003 Regulation of Nobox 1 0.41 0.64 0 98.16
7 INT318006 Regulation of Dmrta1 1 0.41 0.63 0 97.76
8 INT318004 Regulation of Nr5a1 1 0.43 0.63 0 97.48
9 INT299403 Regulation of Star 5 0.39 0.78 0 97.20
10 INT162109 Negative_regulation of Gene_expression of Esr1 4 0.16 2.41 0.12 97.16
11 INT318000 Regulation of Fshr 1 0.41 0.63 0 96.96
12 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15 96.84
13 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 96.72
14 INT318007 Regulation of Lhcgr 1 0.40 0.63 0 96.72
15 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 96.72
16 INT912 Localization of FSHR 91 0.79 23.61 15.58 96.64
17 INT5135 Negative_regulation of GNRH1 106 0.58 36.63 27.71 96.56
18 INT62919 Regulation of Gnas 22 0.43 5.61 9.55 96.44
19 INT155609 Phosphorylation of pid 2 0.54 3.15 1.62 95.88
20 INT318005 Negative_regulation of Dmrta1 1 0.39 1.13 0 95.28
21 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 95.08
22 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 95.08
23 INT35642 Regulation of BPIFA4P 4 0.26 3.85 1.6 94.68
24 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 93.60
25 INT2261 Gene_expression of Lhb 121 0.77 42.78 26.04 93.20
26 INT11831 Positive_regulation of pid 13 0.40 23.37 1.54 93.20
27 INT318008 Positive_regulation of Amh 1 0.25 1.47 0 92.96
28 INT4145 Gene_expression of FSHR 124 0.77 44.98 13.04 92.92
29 INT36132 Negative_regulation of pid 12 0.43 15.15 1.73 92.36
30 INT5128 Positive_regulation of Lhb 232 0.69 44.23 71.26 92.20
31 INT17620 Positive_regulation of Gnrh1 23 0.70 9.77 3.79 92.00
32 INT26538 Positive_regulation of FSHR 103 0.69 30.95 15.33 91.92
33 INT3180 Positive_regulation of PPY 39 0.63 25.57 10.15 91.68
34 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4 91.16
35 INT151947 Positive_regulation of MVD 3 0.67 1.53 2.97 91.16
36 INT206819 Gene_expression of Muc6 7 0.61 4.22 0.19 90.56
37 INT89290 Regulation of MUC1 19 0.45 10.4 0.81 90.16
38 INT32431 Gene_expression of HTC2 17 0.75 9.72 1.93 89.80
39 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 87.60
40 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 87.40
41 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 87.12
42 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19 87.04
43 INT119641 Gene_expression of EBAG9 25 0.76 33.2 3.96 87.00
44 INT185222 Regulation of Gene_expression of EBAG9 5 0.60 4.98 0.64 87.00
45 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 86.64
46 INT105390 Positive_regulation of Gene_expression of HIF1A 27 0.49 26.3 2.88 86.24
47 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66 85.48
48 INT318002 Gene_expression of Dmrta1 1 0.70 1.18 0 85.12
49 INT243713 Positive_regulation of Gene_expression of Gbp1 2 0.12 2.58 0 85.12
50 INT7475 Positive_regulation of Hdl1 138 0.67 175.81 15.05 85.00
51 INT88237 Gene_expression of Gbp1 9 0.65 5.46 0.61 84.28
52 INT206820 Gene_expression of Muc1 17 0.60 13.48 0.36 83.44
53 INT103683 Gene_expression of Muc2 18 0.73 12.47 2.43 83.32
54 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 82.96
55 INT152552 Gene_expression of Muc5ac 24 0.73 19.44 4 82.96
56 INT19078 Binding of Ngf 78 0.48 31.03 44.33 82.92
57 INT11230 Regulation of MUC16 23 0.60 19.54 3.93 82.60
58 INT5126 Positive_regulation of Positive_regulation of Lhb 16 0.48 2.12 5.23 82.44
59 INT151342 Positive_regulation of Positive_regulation of FSHR 5 0.20 1.79 0.11 82.44
60 INT197252 Positive_regulation of Muc1 4 0.50 2.93 0.25 82.40
61 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 82.28
62 INT6557 Gene_expression of Eno2 65 0.77 54.42 8.17 81.60
63 INT24891 Gene_expression of SYP 55 0.75 45.76 7.53 81.60
64 INT8547 Gene_expression of MUC16 116 0.78 75.97 12.18 81.52
65 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 81.28
66 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06 80.64
67 INT75434 Gene_expression of Il13 27 0.52 26.19 15.4 80.08
68 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 79.72
69 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73 79.32
70 INT41892 Gene_expression of HBM 48 0.64 28.32 5.64 78.16
71 INT22022 Regulation of PPY 8 0.26 5.52 5.02 78.08
72 INT23598 Binding of SCN5A 32 0.40 16 5.35 78.04
73 INT22708 Gene_expression of MUC1 297 0.78 232.71 24.19 77.28
74 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88 77.28
75 INT161382 Localization of KRT20 25 0.61 12.97 2.13 77.28
76 INT70021 Localization of BCL2 23 0.74 21.6 1.09 77.28
77 INT1893 Localization of Gh 1041 0.79 340.23 256.58 75.96
78 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 73.68
79 INT8546 Positive_regulation of MUC16 99 0.69 74.98 11.26 72.88
80 INT64157 Positive_regulation of EPCAM 11 0.44 9.09 4.24 72.88
81 INT3725 Localization of Fshb 10 0.68 2.24 1.04 72.32
82 INT197364 Gene_expression of MCAT 18 0.16 24.11 4.27 72.12
83 INT28865 Positive_regulation of Gene_expression of Cea 21 0.57 15.03 2.52 71.64
84 INT1793 Localization of CGA 379 0.81 67.38 114.69 71.00
85 INT2262 Negative_regulation of Lhb 142 0.59 25.47 44.81 68.52
86 INT19844 Negative_regulation of Gene_expression of Lhb 12 0.51 3.19 2.97 68.52
87 INT4360 Gene_expression of Hypism 29 0.22 38.1 4.07 67.92
88 INT249663 Negative_regulation of Phosphorylation of SCN5A 1 0.05 0.74 0.09 67.28
89 INT249661 Positive_regulation of Phosphorylation of SCN5A 1 0.06 0.74 0.09 66.84
90 INT249660 Phosphorylation of SCN5A 1 0.10 0.73 0.09 66.84
91 INT2630 Positive_regulation of Shbg 134 0.70 65.26 15.19 66.60
92 INT72703 Gene_expression of Ide 79 0.70 45.04 4.47 66.24
93 INT115423 Gene_expression of Men1 4 0.47 14.08 0.64 65.12
94 INT308431 Gene_expression of CNC 1 0.01 2.84 0.18 65.12
95 INT34669 Localization of Hypism 8 0.25 10.79 1.2 64.92
96 INT31226 Localization of PPY 20 0.78 9.93 6.8 62.56
97 INT39469 Negative_regulation of Alb 21 0.41 13.33 2.68 55.56
98 INT287308 Negative_regulation of ENO1 5 0.59 4.07 1.24 53.52
99 INT49802 Localization of MUC1 75 0.81 44.74 8.87 53.44
100 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 52.08
101 INT206821 Positive_regulation of Muc2 6 0.47 2.85 0.44 51.36
102 INT206816 Regulation of Muc2 4 0.58 1.06 0.14 51.36
103 INT89105 Gene_expression of Gapdh 27 0.75 4.32 1.15 50.60
104 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 50.00
105 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64 50.00
106 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 50.00
107 INT4991 Positive_regulation of Vim 74 0.69 69.84 8.33 50.00
108 INT239083 Binding of PPY 9 0.32 7.59 2.9 50.00
109 INT23955 Regulation of Vim 16 0.25 14.21 2.04 50.00
110 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52 48.32
111 INT10863 Positive_regulation of Ldlr 45 0.68 31.06 7.05 47.88
112 INT664 Positive_regulation of Fgg 14 0.46 8.75 2.11 47.88
113 INT353111 Positive_regulation of Regulation of Fgg 1 0.01 0.48 0 47.88
114 INT22837 Regulation of Fgg 2 0.10 1.87 0.41 47.40
115 INT193428 Gene_expression of Muc5b 20 0.75 8.15 1.13 46.76
116 INT301360 Gene_expression of Ext1 3 0.68 1.01 0 43.44
117 INT16202 Negative_regulation of Positive_regulation of Shbg 8 0.58 5.24 1.86 43.20
118 INT324046 Gene_expression of Lemd3 1 0.67 1.69 0.1 42.72
119 INT38266 Localization of PTPRC 30 0.68 17.05 1.68 40.20
120 INT206822 Localization of Muc2 11 0.70 5.59 0.58 40.20
121 INT8027 Regulation of Gene_expression of Ngf 34 0.62 26.32 31.16 40.04
122 INT2056 Negative_regulation of Gnrh1 175 0.59 33.43 63.32 37.28
123 INT132068 Gene_expression of Igfbp3 10 0.64 3.73 0.83 36.68
124 INT145860 Negative_regulation of Gene_expression of Igfbp3 2 0.35 1.52 0.27 36.68
125 INT174297 Positive_regulation of MOS 6 0.51 3.26 0.42 30.64
126 INT206823 Localization of Muc5b 5 0.78 5.15 0.43 27.44
127 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24 26.88
128 INT1792 Positive_regulation of CGA 123 0.70 64.73 20.79 25.52
129 INT1794 Regulation of Localization of CGA 136 0.57 13.39 59.07 23.36
130 INT296308 Localization of SPIN1 1 0.12 4.69 0.89 20.80
131 INT4345 Gene_expression of Gtf3a 157 0.67 80.75 48.47 20.56
132 INT65907 Negative_regulation of Gene_expression of Ngf 36 0.59 19.5 20.03 18.60
133 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 17.68
134 INT296309 Binding of SPIN1 1 0.06 3.54 0.72 16.64
135 INT206817 Localization of Muc6 3 0.59 0.8 0.16 16.64
136 INT197250 Localization of Muc5ac 7 0.71 4.83 0.55 15.36
137 INT135299 Binding of PTCH1 10 0.48 12.16 0.84 15.12
138 INT20006 Gene_expression of MT1F 27 0.68 19.55 3.18 13.68
139 INT29740 Gene_expression of ANG 55 0.78 24.53 9.86 13.20
140 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 11.92
141 INT22798 Regulation of Shbg 64 0.60 26.71 8.76 6.96
142 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
143 INT443 Localization of POMC 1020 0.81 284.52 443.17 5.00
144 INT439 Localization of Gnrh1 976 0.81 100.96 363.25 5.00
145 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
146 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
147 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
148 INT1114 Localization of Ins1 748 0.80 192.95 165.48 5.00
149 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
150 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 5.00
151 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 5.00
152 INT920 Localization of PLOD1 223 0.81 42.25 78.7 5.00
153 INT12001 Regulation of Ngf 97 0.62 54.64 76.25 5.00
154 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35 5.00
155 INT3034 Localization of Ngf 126 0.81 50.81 72.84 5.00
156 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 5.00
157 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 5.00
158 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 5.00
159 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
160 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 5.00
161 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 5.00
162 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
163 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 5.00
164 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 5.00
165 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72 5.00
166 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
167 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 5.00
168 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 5.00
169 INT5781 Gene_expression of Edn1 190 0.78 99.1 46 5.00
170 INT2275 Negative_regulation of Localization of Ins1 183 0.59 51.02 44.94 5.00
171 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
172 INT3933 Positive_regulation of PLOD1 128 0.70 30.76 42.03 5.00
173 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52 5.00
174 INT18893 Positive_regulation of CPP 81 0.69 38.03 34.33 5.00
175 INT5868 Positive_regulation of GNRH1 122 0.69 20.96 32.8 5.00
176 INT132161 Gene_expression of MTX1 48 0.58 26.55 32.32 5.00
177 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81 5.00
178 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
179 INT7975 Regulation of PLOD1 97 0.62 20.9 30.51 5.00
180 INT7035 Regulation of CGA 87 0.45 29.04 28.45 5.00
181 INT1638 Negative_regulation of PLOD1 92 0.59 21.69 26.61 5.00
182 INT20462 Binding of ESR1 210 0.44 102.7 26.34 5.00
183 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07 5.00
184 INT5131 Gene_expression of GNRH1 109 0.78 28.79 23.94 5.00
185 INT18894 Gene_expression of CPP 44 0.77 23.05 23.05 5.00
186 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 5.00
187 INT48081 Localization of Il1b 46 0.80 21.59 22.4 5.00
188 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21 5.00
189 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 5.00
190 INT1644 Regulation of FSHR 77 0.55 15.62 21.49 5.00
191 INT78901 Localization of CCL5 67 0.78 40.79 20.59 5.00
192 INT93663 Positive_regulation of MMP1 72 0.67 33.38 19.86 5.00
193 INT5048 Binding of Edn1 55 0.47 18.86 19.16 5.00
194 INT17237 Regulation of Esr1 74 0.43 49.09 17.25 5.00
195 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93 5.00
196 INT7970 Gene_expression of PLOD1 120 0.71 44.42 15.54 5.00
197 INT171666 Regulation of GOPC 117 0.39 40.41 15.47 5.00
198 INT92823 Positive_regulation of Gene_expression of MMP1 65 0.68 25.69 14.31 5.00
199 INT109034 Gene_expression of Eif2ak3 37 0.77 17.11 14.19 5.00
200 INT37722 Gene_expression of NCAM1 103 0.75 81.57 14.18 5.00
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