D:Overdose

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pChart

Disease Term
Synonyms Overdoses
Documents 3183
Hot Single Events 200
Hot Interactions 25

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Overdose. They are ordered first by their relevance to Overdose and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT349586 Aap Regulation of Gene_expression of Ros1 1 0.03 0.56 1.17 99.34
2 INT262367 Tcas1 Positive_regulation of Localization of Adh4 1 0.01 1.91 1.01 99.08
3 INT82554 Sele Regulation of Il6 1 0.25 0.83 0.19 98.18
4 INT81631 Selenbp2 Negative_regulation of Fas 1 0.03 0.77 0.67 97.64
5 INT81630 Selenbp2 Negative_regulation of Positive_regulation of Fas 1 0.03 0.77 0.67 97.64
6 INT245589 Binding of Glb1 and B3galt6 1 0.01 0.94 0 96.96
7 INT57612 Binding of ALB and HGF 1 0.20 0.52 0.18 96.08
8 INT49585 Binding of Glul and Selenbp2 1 0.20 0.19 0.76 93.56
9 INT349588 Aap Positive_regulation of Gene_expression of Ros1 1 0.06 0.73 1.85 92.56
10 INT349589 Aap Positive_regulation of Cyp2e1 1 0.21 1.84 2.71 91.88
11 INT349590 Aap Positive_regulation of Cytl1 1 0.13 1.31 1.15 91.88
12 INT174680 Fos Regulation of Luc7l3 1 0.10 0.87 0.21 90.24
13 INT177358 Ptger1 Positive_regulation of Localization of AMY2A 1 0.00 0.56 0.54 88.88
14 INT177357 Ptger1 Positive_regulation of Gene_expression of AMY2A 1 0.00 0.56 0.54 88.88
15 INT160445 Tpsab1 Positive_regulation of Gene_expression of SPG21 1 0.48 0.96 0.48 88.24
16 INT160444 Tpsab1 Positive_regulation of Gene_expression of CEL 1 0.48 0.96 0.48 88.24
17 INT349576 Binding of Ugt2b and Sult1a1 1 0.00 0.45 1.03 86.88
18 INT69506 CA2 Positive_regulation of PRKCA 1 0.50 0.42 0.98 86.88
19 INT78030 Binding of VEGFC and FCAMR 1 0.01 0.31 0.55 84.52
20 INT20203 Positive_regulation of Binding of TAT and Fgf12 1 0.01 1.51 0.17 83.68
21 INT112869 Aap Positive_regulation of Gpt 2 0.26 0.75 0.6 83.60
22 INT20202 Binding of TAT and Fgf12 1 0.01 1.5 0.17 82.88
23 INT11651 Nlrp1a Negative_regulation of Gpt 1 0.12 0.24 0.47 80.72
24 INT140653 IGF1 Negative_regulation of Protein_catabolism of PARP1 1 0.32 0.63 0.98 80.44
25 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98 80.44
26 INT168010 Asap1 Positive_regulation of HBG2 1 0.01 3.03 1.82 78.16
27 INT349584 Binding of Cyp2e1 and Aap 1 0.10 1.56 3.24 72.12
28 INT191241 SST Regulation of SAE1 1 0.05 0.89 0.18 65.16
29 INT230868 Binding of MCS and TNF 1 0.04 0.77 0.05 64.56
30 INT174679 Homer1 Regulation of Luc7l3 1 0.02 0.67 0.21 62.16
31 INT136346 Binding of Aap and Ads1 1 0.09 2.95 1.44 54.92
32 INT168425 Ptger2 Negative_regulation of RYBP Positive_regulation of Nfkb1 1 0.01 0.27 0.19 54.88
33 INT168427 RYBP Positive_regulation of Nfkb1 1 0.01 0.53 0.38 54.28
34 INT347396 RYBP Positive_regulation of Binding of Sdcbp 1 0.00 0.92 1.66 51.72
35 INT168424 Ptger2 Regulation of Binding of Nos2 1 0.22 0.52 0.36 51.32
36 INT168423 Ptger2 Regulation of Nos2 1 0.13 0.52 0.36 51.32
37 INT347369 RYBP Positive_regulation of GSR 1 0.01 0.43 0.51 49.96
38 INT347395 RYBP Positive_regulation of Gsr 1 0.01 0.43 0.5 49.96
39 INT168426 RYBP Regulation of Nos2 1 0.01 0.4 0.36 49.88
40 INT129594 St13 Positive_regulation of Positive_regulation of Tnf 1 0.26 0.85 0.21 49.76
41 INT250589 Binding of SLC16A7 and MCTS1 1 0.14 0 0 49.56
42 INT250590 Binding of SLC16A4 and MCTS1 1 0.12 0 0 49.56
43 INT129592 St13 Positive_regulation of Protein_catabolism of Stat3 1 0.26 0.84 0.16 47.20
44 INT129593 St13 Positive_regulation of Positive_regulation of Stat3 1 0.28 0.84 0.16 47.20
45 INT112870 Aap Positive_regulation of Gene_expression of Ccnd1 1 0.24 0.34 0.63 47.12
46 INT25296 Oxt Regulation of Localization of Crh 1 0.01 0.18 0.07 46.40
47 INT250630 CLTC Negative_regulation of Gene_expression of Fbxo23 1 0.00 0 0 43.20
48 INT340277 Tnfsf11 Positive_regulation of TRAP 1 0.03 0.76 0 38.20
49 INT340238 Tnfsf11 Positive_regulation of Gene_expression of Fig4 1 0.02 0.4 0 38.20
50 INT315259 Binding of Nfe2l2 and Gcat 1 0.00 0.52 0 33.48
51 INT349585 Aap Positive_regulation of Etf1 1 0.00 1.68 1.94 29.76
52 INT250634 MCTS1 Positive_regulation of Fbxo23 1 0.02 0 0 23.92
53 INT353337 F2r Positive_regulation of Gene_expression of Mif 1 0.46 0 0 22.36
54 INT250633 MCTS1 Positive_regulation of Gene_expression of Fbxo23 1 0.02 0 0.03 15.72
55 INT250632 Binding of MCPH1 and Fbxo23 1 0.01 0 0.11 12.72
56 INT250631 MCTS1 Regulation of Fbxo23 1 0.02 0 0 11.92
57 INT340270 Negative_regulation of Tnfsf11 Positive_regulation of TRAP 1 0.03 0.37 0 11.04
58 INT330984 Negative_regulation of CYP2D6 Positive_regulation of Localization of CYP1A2 1 0.46 0 0.62 10.60
59 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62 5.00
60 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 5.00
61 INT351352 Binding of Trpv1 and Lpar1 1 0.21 5.86 4.62 5.00
62 INT186566 Hpcl1 Positive_regulation of Fos 1 0.17 0.38 4.49 5.00
63 INT349583 Aap Positive_regulation of Gene_expression of Cyp2e1 1 0.18 1.57 3.59 5.00
64 INT158770 Binding of Trpv1 and Trpa1 5 0.34 2.07 3.5 5.00
65 INT351349 Prkcg Positive_regulation of Binding of Lpar1 1 0.15 2 2.82 5.00
66 INT210696 Trpv1 Regulation of Slc12a2 1 0.25 1.97 2.58 5.00
67 INT153728 RYBP Positive_regulation of Gpt 3 0.03 2.01 2.36 5.00
68 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14 5.00
69 INT117794 Hpcl1 Positive_regulation of Gene_expression of Fos 3 0.17 0.15 1.98 5.00
70 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95 5.00
71 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95 5.00
72 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9 5.00
73 INT297488 Itpr3 Regulation of Positive_regulation of Ltp 1 0.02 0.47 1.87 5.00
74 INT100771 Binding of Itga1 and Vcam1 3 0.11 3.91 1.79 5.00
75 INT336556 SLC6A3 Positive_regulation of Gene_expression of GOPC 1 0.08 1.87 1.76 5.00
76 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75 5.00
77 INT185143 Elane Positive_regulation of Pik3r1 1 0.01 0 1.72 5.00
78 INT45306 Pomc Positive_regulation of ENG 2 0.07 1.11 1.68 5.00
79 INT297489 Ryr2 Regulation of Positive_regulation of Ltp 1 0.05 0.16 1.64 5.00
80 INT237286 Dlat Regulation of Prep 1 0.01 0 1.57 5.00
81 INT347397 RYBP Positive_regulation of Sdcbp 1 0.00 0.22 1.56 5.00
82 INT208980 Binding of Ca2 and Trpv1 4 0.32 0.67 1.55 5.00
83 INT274943 Positive_regulation of Ltp Positive_regulation of Positive_regulation of Tac2 1 0.04 0.49 1.53 5.00
84 INT351366 LPA Positive_regulation of Rab38 1 0.00 0.95 1.53 5.00
85 INT72666 Binding of ODT and Oprm1 1 0.03 0.53 1.5 5.00
86 INT246519 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.25 0.08 1.42 5.00
87 INT238009 Binding of Cxcr3 and Cxcl9 3 0.40 4.01 1.37 5.00
88 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32 5.00
89 INT281479 Drd2 Positive_regulation of Penk 1 0.23 0.4 1.3 5.00
90 INT116892 Binding of TRPV1 and Phax 4 0.00 0.1 1.24 5.00
91 INT274948 Binding of Dh and Ltp 1 0.11 0.55 1.23 5.00
92 INT197231 Grik1 Regulation of Gabrg1 1 0.19 0.13 1.22 5.00
93 INT285185 Binding of Ca2 and Cd2 1 0.25 0.24 1.21 5.00
94 INT349587 Binding of Aap and Csf2 1 0.04 0.41 1.18 5.00
95 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16 5.00
96 INT326665 Cpe Positive_regulation of Oprd1 1 0.01 1.24 1.15 5.00
97 INT336559 SLC6A3 Positive_regulation of GOPC 1 0.08 1 1.15 5.00
98 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11 5.00
99 INT235709 Binding of NA and SSR1 1 0.07 0.72 1.08 5.00
100 INT297491 Positive_regulation of Lta Positive_regulation of Ltp 1 0.00 0.16 1.06 5.00
101 INT30905 SST Negative_regulation of Localization of GCG 2 0.12 1.56 1.04 5.00
102 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03 5.00
103 INT297487 Negative_regulation of Slc1a2 Negative_regulation of Positive_regulation of Ltp 1 0.01 0.46 1.03 5.00
104 INT297486 Slc1a2 Negative_regulation of Positive_regulation of Ltp 1 0.01 0.45 1.02 5.00
105 INT197241 Kars Regulation of Localization of Gabrg1 1 0.23 0 1.02 5.00
106 INT189844 Churc1 Positive_regulation of Cnr2 1 0.01 0.79 1.02 5.00
107 INT349592 GTF2H5 Negative_regulation of Cyp2c22 1 0.00 0.64 0.98 5.00
108 INT93306 Binding of TRPV1 and CAP1 2 0.18 0.07 0.97 5.00
109 INT75283 SST Negative_regulation of Localization of INS 2 0.47 1.45 0.96 5.00
110 INT186568 Hpcl1 Regulation of Gene_expression of Fos 1 0.22 0.07 0.94 5.00
111 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93 5.00
112 INT309708 Palm Regulation of Positive_regulation of Penk 1 0.19 1.25 0.91 5.00
113 INT343918 IgG Positive_regulation of Phosphorylation of MAPK1 1 0.01 3.57 0.91 5.00
114 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91 5.00
115 INT291011 Pomc Regulation of Gene_expression of ENG 1 0.08 0.86 0.91 5.00
116 INT247759 Binding of Ccrl2 and Rarres2 1 0.26 1.19 0.9 5.00
117 INT343834 Binding of CD14 and IRF6 1 0.02 2.08 0.9 5.00
118 INT257304 Pde5a Positive_regulation of Oprd1 1 0.15 0.48 0.89 5.00
119 INT326663 Bdnf Regulation of Positive_regulation of Arc 1 0.16 1.46 0.88 5.00
120 INT281482 Drd2 Positive_regulation of Drd2 Positive_regulation of Penk 1 0.21 0.27 0.87 5.00
121 INT343847 IRF6 Positive_regulation of TBCE 1 0.01 1.11 0.87 5.00
122 INT326664 Bdnf Positive_regulation of Arc 1 0.27 1.07 0.86 5.00
123 INT326661 Bdnf Positive_regulation of Gene_expression of Arc 1 0.27 1.96 0.86 5.00
124 INT343829 TLR1 Positive_regulation of TBCE 1 0.03 0.96 0.85 5.00
125 INT250861 Fgf8 Positive_regulation of Gene_expression of Ptger2 1 0.04 1.51 0.84 5.00
126 INT249656 tm Positive_regulation of Il12a 1 0.07 1.17 0.84 5.00
127 INT243678 Binding of GSR and Ugcg 2 0.03 2.84 0.83 5.00
128 INT186567 Negative_regulation of Hpcl1 Positive_regulation of Fos 1 0.11 0.07 0.82 5.00
129 INT303656 SST Negative_regulation of Localization of GAST 1 0.12 1.45 0.82 5.00
130 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8 5.00
131 INT182839 Camk4 Positive_regulation of Creb1 3 0.49 1.81 0.79 5.00
132 INT228054 Fpr3 Positive_regulation of Il10 1 0.05 0.9 0.79 5.00
133 INT347391 Positive_regulation of RYBP Positive_regulation of Sdcbp 1 0.00 0.22 0.79 5.00
134 INT347398 RYBP Positive_regulation of Positive_regulation of Sdcbp 1 0.00 0.22 0.79 5.00
135 INT222024 Mapk8 Regulation of Mapk14 2 0.17 0.83 0.79 5.00
136 INT239671 Binding of Ccl2 and Gtf3a 1 0.02 1.34 0.79 5.00
137 INT347373 RYBP Positive_regulation of Sdcbp Positive_regulation of Lpo 1 0.00 0 0.78 5.00
138 INT351364 LPA Positive_regulation of Trpv1 1 0.02 1.15 0.78 5.00
139 INT224281 Bdnf Regulation of Gene_expression of Gap43 1 0.36 0.4 0.77 5.00
140 INT347394 RYBP Positive_regulation of Lpo 1 0.02 0 0.77 5.00
141 INT347368 RYBP Negative_regulation of GSTK1 1 0.00 0 0.77 5.00
142 INT224280 Bdnf Positive_regulation of Creb1 3 0.30 0.62 0.77 5.00
143 INT224283 Bdnf Regulation of Gene_expression of Calca 1 0.19 0.35 0.76 5.00
144 INT332699 Binding of KNG1 and TRGC1 1 0.16 3.37 0.75 5.00
145 INT185140 Elane Positive_regulation of Prkca 1 0.00 0 0.74 5.00
146 INT177359 Serpinc1 Positive_regulation of CSRP1 1 0.00 0.97 0.72 5.00
147 INT351351 Prkcg Regulation of Lpar1 1 0.12 0.58 0.72 5.00
148 INT351350 Prkaca Regulation of Lpar1 1 0.04 0.58 0.72 5.00
149 INT197234 Grik1 Positive_regulation of Localization of Gabrg1 1 0.15 0.82 0.71 5.00
150 INT307754 Ik Negative_regulation of Trpa1 1 0.07 0.08 0.71 5.00
151 INT297490 Itpr3 Regulation of Ltp 1 0.02 0 0.7 5.00
152 INT257302 Cnp Regulation of Protein_catabolism of Pde5a 1 0.05 0.49 0.7 5.00
153 INT89936 Tlr4 Positive_regulation of Il6 3 0.49 0.95 0.7 5.00
154 INT351367 LPA Regulation of Trpv1 1 0.01 0.83 0.69 5.00
155 INT197233 Positive_regulation of Rora Positive_regulation of Localization of Helt 1 0.00 0 0.68 5.00
156 INT250871 Il1a Positive_regulation of Protein_catabolism of Ecm1 1 0.01 1.44 0.68 5.00
157 INT246335 Fig4 Regulation of Localization of P2rx7 1 0.01 0 0.67 5.00
158 INT246336 Fig4 Regulation of Localization of Nts 1 0.18 0 0.66 5.00
159 INT343851 Positive_regulation of Binding of IRF6 and TLR4 1 0.07 1.96 0.66 5.00
160 INT186569 Regulation of Hpcl1 Positive_regulation of Fos 1 0.07 0 0.65 5.00
161 INT197240 Grik2 Regulation of Gene_expression of Gabrg1 1 0.08 0.13 0.64 5.00
162 INT197238 Grik1 Regulation of Gene_expression of Gabrg1 1 0.17 0.13 0.64 5.00
163 INT197236 Grik2 Regulation of Gabrg1 1 0.08 0.13 0.64 5.00
164 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63 5.00
165 INT347393 RYBP Negative_regulation of Ugcg 1 0.01 0 0.63 5.00
166 INT237285 Dlat Negative_regulation of Prep 1 0.01 0 0.62 5.00
167 INT265707 Binding of NA and Cfp 1 0.01 0 0.62 5.00
168 INT197239 Grik1 Regulation of Localization of Gabrg1 1 0.10 0.56 0.61 5.00
169 INT267625 Binding of KNG1 and Klk1 2 0.21 2.23 0.61 5.00
170 INT179203 NLRP1 Regulation of Gene_expression of TNF 1 0.31 1.73 0.6 5.00
171 INT208372 Il13 Positive_regulation of Ahr 1 0.21 1.22 0.59 5.00
172 INT315334 Binding of CYP3A4 and CDIPT 3 0.04 0.85 0.59 5.00
173 INT192873 Binding of RS1 and Nktcn1 1 0.00 0.8 0.59 5.00
174 INT336557 SLC6A3 Positive_regulation of Binding of GOPC 1 0.08 0.5 0.58 5.00
175 INT347362 RYBP Regulation of Gene_expression of GSR 1 0.01 0 0.57 5.00
176 INT347400 RYBP Regulation of Gene_expression of Ugcg 1 0.01 0 0.57 5.00
177 INT303652 Binding of SST and SSTR2 1 0.26 0.46 0.57 5.00
178 INT303654 Binding of SST and SSTR5 1 0.22 0.46 0.57 5.00
179 INT347366 RYBP Regulation of Gene_expression of GSTK1 1 0.00 0 0.57 5.00
180 INT296169 Binding of Htr4 and Creb1 1 0.49 0.1 0.56 5.00
181 INT308891 Adp Positive_regulation of P2ry13 1 0.15 0.11 0.55 5.00
182 INT308895 Adp Positive_regulation of P2ry12 1 0.14 0.11 0.55 5.00
183 INT250852 Fgf8 Negative_regulation of Gene_expression of Ecm1 1 0.04 1.1 0.54 5.00
184 INT351365 LPA Positive_regulation of Localization of Il6 1 0.00 1.79 0.54 5.00
185 INT303653 Binding of DRD2 and SST 1 0.18 0.45 0.54 5.00
186 INT343913 Binding of FOS and Smad3 1 0.19 0.92 0.54 5.00
187 INT127320 Gpx3 Regulation of Akt1 2 0.00 3.11 0.53 5.00
188 INT308894 Adp Regulation of P2ry1 1 0.05 0.49 0.53 5.00
189 INT274935 Ltp Positive_regulation of Localization of Ephb6 1 0.33 0 0.52 5.00
190 INT274938 Ltp Positive_regulation of Localization of Ephb2 1 0.25 0 0.52 5.00
191 INT297479 Ryr2 Positive_regulation of Ca2 1 0.22 0 0.52 5.00
192 INT343838 EDA Positive_regulation of TLR4 1 0.11 0.87 0.51 5.00
193 INT343859 Binding of IRF6 and TBCE 1 0.01 1.1 0.51 5.00
194 INT343860 Binding of CD14 and TBCE 1 0.03 1.1 0.51 5.00
195 INT343825 IRF6 Regulation of Gene_expression of FUT1 1 0.00 1.74 0.5 5.00
196 INT230532 LILRB1 Positive_regulation of Gene_expression of Mmp2 1 0.14 1.04 0.5 5.00
197 INT230533 LILRB1 Positive_regulation of Positive_regulation of Mmp9 1 0.20 1.03 0.5 5.00
198 INT273350 Pde7a Positive_regulation of Localization of Pde4d 1 0.33 1.35 0.49 5.00
199 INT274945 Binding of Fcgr1 and Gopc 1 0.02 0 0.49 5.00
200 INT347392 RYBP Regulation of Ugcg 1 0.01 0.06 0.48 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Overdose. They are ordered first by their pain relevance and then by number of times they were reported in Overdose. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT11298 Gene_expression of Ido1 6 0.58 6.71 4.85 100.00
2 INT150248 Positive_regulation of Gene_expression of Ido1 2 0.43 2.68 1.77 100.00
3 INT122419 Transcription of ABCC1 10 0.70 4.45 4.61 100.00
4 INT115665 Transcription of ABCB1 9 0.71 3.69 1.91 100.00
5 INT143557 Positive_regulation of Ido1 6 0.40 5.34 4.8 100.00
6 INT169643 Binding of Ods 3 0.18 2.89 1.15 100.00
7 INT145273 Transcription of ABCG2 2 0.69 1.72 1.25 100.00
8 INT100262 Positive_regulation of Positive_regulation of Cyp2e1 7 0.50 2.39 4.31 99.98
9 INT11649 Negative_regulation of Positive_regulation of Gpt 25 0.59 13.94 10.87 99.98
10 INT80950 Regulation of RGD1309906 1 0.62 0.43 1.13 99.98
11 INT146785 Positive_regulation of Localization of Bax 7 0.69 6.16 1.47 99.98
12 INT11180 Binding of RYBP 52 0.46 13.86 42.53 99.96
13 INT61118 Gene_expression of Nefl 11 0.75 4.02 4.02 99.92
14 INT29393 Positive_regulation of APRT 18 0.67 5.28 2.13 99.88
15 INT70724 Positive_regulation of Negative_regulation of ADRB1 1 0.38 0.2 0.86 99.86
16 INT70726 Positive_regulation of Negative_regulation of ADRB2 1 0.49 0.2 0.86 99.86
17 INT129227 Binding of DNASE1 4 0.14 2.54 0.54 99.84
18 INT309839 Binding of Nlrp1a 5 0.29 1.95 0.38 99.84
19 INT112692 Localization of Bax 31 0.80 20.97 3.98 99.82
20 INT30170 Gene_expression of Car2 330 0.66 77.26 46.76 99.82
21 INT717 Regulation of F2 29 0.61 17.46 6.99 99.80
22 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 99.78
23 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 99.72
24 INT60542 Positive_regulation of Gene_expression of GSTK1 11 0.39 6.21 1.13 99.72
25 INT28802 Binding of F2 15 0.47 8.8 3.47 99.70
26 INT82744 Regulation of Gene_expression of Myh13 2 0.59 2.09 0.47 99.68
27 INT37570 Localization of Otc 2 0.61 0.97 0.25 99.68
28 INT53749 Positive_regulation of Positive_regulation of RYBP 4 0.09 2.48 3.6 99.66
29 INT32312 Gene_expression of UGP2 1 0.60 1.35 2.24 99.64
30 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35 99.64
31 INT36449 Negative_regulation of G6PD 74 0.59 54.15 8.85 99.62
32 INT3074 Negative_regulation of Chkb 29 0.57 14 12.04 99.62
33 INT484 Negative_regulation of ADRB2 13 0.59 2.85 3.94 99.62
34 INT123813 Positive_regulation of Parp1 74 0.70 65.36 8.56 99.56
35 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38 99.56
36 INT20200 Positive_regulation of Serpinc1 25 0.68 17.08 4.98 99.56
37 INT137679 Localization of Gfm1 18 0.08 9.58 3.24 99.52
38 INT78914 Positive_regulation of ABCC1 19 0.67 7.99 5.18 99.52
39 INT120595 Positive_regulation of ABCC4 3 0.51 2.83 1.91 99.52
40 INT145272 Positive_regulation of Transcription of ABCC1 2 0.49 1.31 1.42 99.52
41 INT57645 Gene_expression of GSTK1 54 0.62 21.05 4.2 99.52
42 INT13467 Positive_regulation of ABCB1 36 0.68 9.68 8.95 99.48
43 INT145274 Positive_regulation of ABCG2 5 0.67 3.46 2.24 99.48
44 INT145268 Positive_regulation of ABCC5 1 0.58 2.62 1.13 99.48
45 INT76008 Positive_regulation of ADAR 7 0.60 2.24 2 99.48
46 INT39469 Negative_regulation of Alb 21 0.41 13.33 2.68 99.44
47 INT267904 Binding of TCHH 1 0.33 0.96 0 99.44
48 INT25666 Negative_regulation of ADRB1 11 0.44 3.12 2.33 99.40
49 INT22967 Positive_regulation of RYBP 94 0.56 37.04 85.92 99.36
50 INT160180 Positive_regulation of Fbxo23 3 0.35 1.7 1.03 99.36
51 INT90357 Regulation of BCL10 3 0.05 3.23 0.56 99.28
52 INT17565 Regulation of Gpt 85 0.60 43.64 13.68 99.24
53 INT94406 Regulation of Slc17a5 10 0.44 3.71 3.77 99.24
54 INT82345 Regulation of Slc40a1 2 0.23 0.33 1.28 99.24
55 INT14436 Gene_expression of Dbh 42 0.72 9.9 19.85 99.22
56 INT11650 Negative_regulation of Gpt 122 0.59 69.15 30.36 99.20
57 INT70816 Negative_regulation of Fos 32 0.58 13 11.18 99.20
58 INT115528 Binding of Ros1 37 0.41 22.96 5.5 99.18
59 INT97646 Binding of Gc 6 0.36 3.56 1.32 99.16
60 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 99.16
61 INT64723 Regulation of Positive_regulation of IL6 13 0.61 12.59 5.19 99.16
62 INT68255 Regulation of Positive_regulation of IL8 12 0.41 5.71 3.91 99.16
63 INT113906 Regulation of Positive_regulation of CCL2 4 0.27 3.2 2.17 99.16
64 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 99.16
65 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.16
66 INT126683 Localization of Lipg 7 0.70 3.87 0.46 99.16
67 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 99.10
68 INT79456 Gene_expression of PDE4A 35 0.77 19.42 7.42 99.08
69 INT79455 Positive_regulation of Gene_expression of PDE4A 3 0.67 2.07 1.5 99.08
70 INT108919 Positive_regulation of Mapk9 9 0.34 3.55 4.74 99.08
71 INT108921 Negative_regulation of Positive_regulation of Mapk9 3 0.25 1.8 1.99 99.08
72 INT2040 Positive_regulation of CYP2B6 95 0.69 34.3 25.6 99.04
73 INT81411 Negative_regulation of Sele 8 0.38 7 2.7 99.04
74 INT82552 Negative_regulation of Regulation of Il6 2 0.38 1.43 0.36 99.04
75 INT82553 Negative_regulation of Regulation of Sele 1 0.38 0.84 0.19 99.04
76 INT153329 Gene_expression of Cm9 6 0.67 4.35 0.95 98.98
77 INT145270 Gene_expression of ABCG2 19 0.75 7.87 2.69 98.96
78 INT145269 Transcription of ABCC4 1 0.39 1.18 0.53 98.96
79 INT7845 Regulation of OPRK1 44 0.62 4.54 30.49 98.92
80 INT82989 Regulation of DRD3 1 0.23 0.45 0.99 98.92
81 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 98.88
82 INT174675 Negative_regulation of Luc7l3 5 0.18 2.09 2.65 98.88
83 INT66274 Gene_expression of Ctbs 9 0.39 1.16 1.35 98.86
84 INT12035 Regulation of F2 21 0.45 12.66 1.47 98.84
85 INT31403 Positive_regulation of AFM 3 0.29 5.57 1.38 98.84
86 INT110260 Positive_regulation of Fgf14 1 0.07 0.8 0.35 98.84
87 INT20307 Positive_regulation of Cyp2e1 70 0.70 23.59 32.49 98.78
88 INT63979 Regulation of Sele 13 0.54 10.64 3.7 98.78
89 INT11013 Negative_regulation of Phosphorylation of Creb1 55 0.59 18.74 34.66 98.76
90 INT61160 Negative_regulation of Gene_expression of Creb1 37 0.59 17.95 23.17 98.76
91 INT4134 Negative_regulation of Glce 11 0.58 2.97 4.28 98.76
92 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 98.76
93 INT71763 Gene_expression of Mri1 33 0.58 12.56 8.6 98.76
94 INT123814 Positive_regulation of Positive_regulation of Parp1 9 0.50 9.32 0.57 98.76
95 INT62579 Negative_regulation of Gene_expression of Cyp2e1 8 0.59 2.95 5.48 98.74
96 INT6855 Binding of NCOR2 71 0.41 15.64 28.96 98.72
97 INT57549 Gene_expression of GNPTAB 49 0.65 57.5 9.05 98.72
98 INT57665 Negative_regulation of Cyp2e1 35 0.59 8.05 9.29 98.72
99 INT53387 Negative_regulation of Positive_regulation of Cyp2e1 3 0.42 1.28 1.98 98.72
100 INT7364 Regulation of Ghrh 49 0.58 8.05 19.05 98.72
101 INT64649 Binding of Abp1 1 0.30 0.29 1.45 98.72
102 INT35716 Positive_regulation of NCOR2 45 0.60 18 23.54 98.70
103 INT1038 Negative_regulation of F2 26 0.58 15.12 6.75 98.68
104 INT138506 Negative_regulation of F3 2 0.04 1.23 0.2 98.68
105 INT82745 Gene_expression of Myh13 7 0.78 8.16 2.28 98.64
106 INT82991 Regulation of Gene_expression of DRD3 1 0.23 0.59 1.26 98.64
107 INT82988 Regulation of Transcription of DRD3 1 0.38 0.59 1.26 98.64
108 INT52916 Negative_regulation of Prkca 9 0.54 2.4 10.79 98.64
109 INT118343 Positive_regulation of Eae1 121 0.39 136.06 34.87 98.64
110 INT140054 Negative_regulation of Mapk9 3 0.25 1.9 1.05 98.64
111 INT108173 Gene_expression of Abcb1b 14 0.75 8.61 4.26 98.60
112 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51 98.60
113 INT69442 Regulation of Otc 3 0.24 0.98 1.04 98.60
114 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 98.54
115 INT62580 Gene_expression of Cyp2e1 31 0.78 15.4 11.08 98.52
116 INT60148 Regulation of Sigmar1 20 0.43 7.23 7.76 98.52
117 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97 98.50
118 INT47859 Negative_regulation of Cyp2e1 41 0.59 16.92 21.72 98.40
119 INT82992 Gene_expression of DRD3 3 0.50 2.12 2.88 98.40
120 INT82987 Transcription of DRD3 1 0.58 0.59 1.25 98.40
121 INT98205 Gene_expression of PCBD1 10 0.61 14.78 7.27 98.40
122 INT82722 Negative_regulation of Positive_regulation of Cyp2e1 6 0.59 3.74 2.02 98.40
123 INT100158 Negative_regulation of Positive_regulation of Zap70 1 0.41 0.44 0.77 98.40
124 INT257364 Positive_regulation of Gene_expression of PCBD1 1 0.28 0.54 0.11 98.40
125 INT32313 Positive_regulation of Gene_expression of UGP2 1 0.47 0.4 0.71 98.38
126 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78 98.36
127 INT72864 Positive_regulation of Gene_expression of Sele 9 0.68 7.46 1.14 98.36
128 INT812 Localization of INS 1026 0.81 515.6 145.31 98.30
129 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 98.24
130 INT15913 Negative_regulation of CYP2D6 174 0.59 22.45 70.91 98.24
131 INT93204 Localization of Sparc 2 0.72 2.98 2.24 98.24
132 INT47175 Negative_regulation of Negative_regulation of AGL 4 0.24 1.19 0.36 98.24
133 INT220295 Gene_expression of MARS 6 0.47 4.74 0.35 98.24
134 INT220294 Positive_regulation of Gene_expression of MARS 3 0.35 2.45 0.05 98.24
135 INT10889 Gene_expression of F8 60 0.78 41.36 5.06 98.20
136 INT49651 Gene_expression of Creb1 276 0.78 114.77 111.96 98.12
137 INT18774 Gene_expression of RYBP 67 0.65 47.66 37.59 98.08
138 INT80447 Negative_regulation of ARRB2 5 0.39 3.12 6.3 98.08
139 INT116538 Negative_regulation of GRK6 1 0.48 0.84 3.31 98.08
140 INT110503 Negative_regulation of ADRBK1 4 0.53 0.71 2.69 98.08
141 INT35745 Negative_regulation of AGL 29 0.50 9.16 2.03 98.08
142 INT53747 Positive_regulation of Cyp2e1 34 0.70 29.03 13.39 97.96
143 INT72060 Positive_regulation of Gene_expression of Ros1 127 0.41 76.76 20.91 97.86
144 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 97.76
145 INT64454 Positive_regulation of Ctsd 2 0.44 1.14 0.57 97.76
146 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 97.76
147 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 97.76
148 INT49487 Gene_expression of Sele 65 0.76 68.11 19.41 97.76
149 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 97.76
150 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4 97.76
151 INT49751 Negative_regulation of Positive_regulation of PTGS1 12 0.45 4.73 7.23 97.76
152 INT88020 Positive_regulation of Fas 32 0.70 19.78 9.97 97.72
153 INT10706 Regulation of Il6 150 0.62 93.23 62.34 97.70
154 INT82990 Binding of POLR3D 1 0.02 0.42 0.99 97.64
155 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 97.60
156 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 97.58
157 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 97.56
158 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54 97.52
159 INT23564 Negative_regulation of Car2 103 0.50 27.28 21.86 97.52
160 INT60281 Negative_regulation of Negative_regulation of Car2 4 0.36 1.88 1.26 97.52
161 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 97.48
162 INT80657 Gene_expression of SLC17A5 50 0.75 39.98 5.44 97.48
163 INT14599 Localization of Tpsab1 36 0.79 14.58 7.18 97.48
164 INT158596 Binding of Tlr3 24 0.47 11.66 3.69 97.48
165 INT204524 Binding of TLR9 17 0.43 11.69 2.76 97.48
166 INT280014 Binding of TLR7 4 0.14 3.52 0.76 97.48
167 INT322032 Binding of TLR8 3 0.32 2.57 0.69 97.48
168 INT97171 Localization of Ear1 7 0.43 4.25 0.44 97.48
169 INT154970 Localization of Bax 15 0.74 11.12 2.11 97.44
170 INT101108 Localization of Bcl2 16 0.72 11.68 1.86 97.44
171 INT15529 Gene_expression of GCG 51 0.75 18.55 8.35 97.40
172 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 97.36
173 INT22213 Localization of Gpt 52 0.78 34.05 12.94 97.34
174 INT22214 Positive_regulation of Localization of Gpt 14 0.62 8.42 7.89 97.34
175 INT54473 Binding of ABCB1 30 0.48 8.65 10.38 97.28
176 INT651 Positive_regulation of PTGS1 93 0.69 37.27 29.18 97.28
177 INT262366 Localization of Adh4 1 0.78 1.88 1 97.28
178 INT35708 Protein_catabolism of RYBP 7 0.96 0.86 4.86 97.24
179 INT77407 Regulation of Gene_expression of OPRM1 51 0.62 12.58 35.75 97.22
180 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 97.20
181 INT14152 Gene_expression of Slc17a5 46 0.61 20.01 15.9 97.20
182 INT69989 Negative_regulation of Gene_expression of Nefl 2 0.43 0.44 0.67 97.20
183 INT52457 Gene_expression of ABCB1 129 0.78 38.68 19.88 97.16
184 INT723 Regulation of Gc 1 0.20 0.57 0.54 97.16
185 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 97.06
186 INT11624 Gene_expression of OPRM1 445 0.78 72.36 294.36 96.94
187 INT82839 Negative_regulation of ABCB1 61 0.59 16.09 8.83 96.88
188 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48 96.80
189 INT21687 Positive_regulation of ras 143 0.58 97.34 27.31 96.72
190 INT267903 Negative_regulation of TCHH 1 0.37 1.54 0.15 96.72
191 INT49488 Gene_expression of mMCP-7 37 0.75 26.11 7.68 96.72
192 INT122093 Localization of Btd 1 0.80 0.36 0.24 96.64
193 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 96.56
194 INT20201 Positive_regulation of Fgf12 8 0.43 15.13 0.98 96.56
195 INT308499 Positive_regulation of Gv2 1 0.03 0.53 0.18 96.56
196 INT27415 Negative_regulation of Positive_regulation of Got1 15 0.51 10.99 5.14 96.52
197 INT35744 Binding of MAOB 13 0.46 7.52 4.26 96.52
198 INT145271 Positive_regulation of Gene_expression of ABCG2 5 0.49 3.97 0.9 96.48
199 INT131552 Gene_expression of ABCC5 3 0.50 1.38 0.7 96.48
200 INT120596 Gene_expression of ABCC4 11 0.78 2.51 3.76 96.48
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