D:Overweight

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pChart

Disease Term
Synonyms None
Documents 1310
Hot Single Events 200
Hot Interactions 21

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Overweight. They are ordered first by their relevance to Overweight and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT355687 Art2b Positive_regulation of Gene_expression of Mc3r 1 0.02 1.01 0.48 99.10
2 INT323878 Binding of LEP and MMP13 1 0.17 0.77 0.05 98.24
3 INT353062 HSD11B1 Regulation of Gene_expression of ADIPOQ 1 0.13 5.03 0 97.68
4 INT353061 HSD11B1 Regulation of Gene_expression of LEP 1 0.20 5.03 0 97.68
5 INT323868 LEP Regulation of Transcription of COL1A2 1 0.10 0.98 0.09 97.00
6 INT65644 Binding of AFA and Dbp 1 0.10 0.86 0.1 96.24
7 INT323883 BMI1 Regulation of LEP 1 0.02 2.39 0.23 94.32
8 INT323876 LEP Regulation of COL1A2 1 0.10 0.86 0.08 93.84
9 INT290026 Binding of PPARG and CHDH 1 0.10 6.61 0 91.52
10 INT155388 Binding of LPA and Lipg 1 0.00 1.22 0.12 89.24
11 INT155387 Binding of LPA and RT1-A 1 0.00 1.22 0.12 89.24
12 INT290022 Binding of PPARG and DDX12P 1 0.00 1.77 0 87.84
13 INT314623 Ex Positive_regulation of INS 1 0.10 1.46 0 87.60
14 INT171250 Binding of BMI1 and OAP 1 0.13 1.02 0.22 86.56
15 INT323872 LEP Positive_regulation of Gene_expression of IGF1 1 0.35 0.77 0.07 86.24
16 INT323871 LEP Regulation of Gene_expression of IGF1 1 0.14 1.19 0.11 85.12
17 INT323880 Binding of BMI1 and LEP 1 0.02 3.97 0.41 84.72
18 INT323881 BMI1 Regulation of Gene_expression of LEP 1 0.03 1.09 0.08 83.60
19 INT278184 Binding of Crp and Hdlcl1 1 0.01 2.72 0.09 83.00
20 INT323886 BMI1 Regulation of Gene_expression of MMP13 1 0.01 1.13 0.12 82.88
21 INT323870 LEP Regulation of Gene_expression of MMP13 1 0.21 1.76 0.33 82.32
22 INT323875 Binding of BMI1 and IGF1 1 0.01 1.2 0.11 79.04
23 INT323882 Binding of BMI1 and MMP13 1 0.01 1.26 0.11 79.04
24 INT323869 Binding of BMI1 and COL1A2 1 0.00 1.21 0.11 79.04
25 INT270746 INS Regulation of LEP 1 0.07 0.72 0.11 78.00
26 INT290028 Binding of SUGT1 and CHDH 1 0.00 0.88 0 77.76
27 INT323879 LEP Regulation of SOAT1 1 0.15 1.15 0.1 73.48
28 INT204319 SIRT1 Regulation of Gene_expression of PPARGC1A 1 0.50 0.12 0 69.84
29 INT197727 Binding of RARA and Positive_regulation of PPARA 1 0.02 0.96 0.05 67.64
30 INT197741 Binding of Rdh5 and Positive_regulation of PPARA 1 0.27 0.95 0.05 67.64
31 INT332637 Negative_regulation of Dpp4 Negative_regulation of Localization of Ins1 1 0.06 1.66 0.1 62.28
32 INT207550 GH1 Regulation of Binding of GH1 and INS 1 0.22 0.55 0.07 58.76
33 INT207552 Binding of GH1 and INS 1 0.23 0.55 0.07 58.76
34 INT254497 GOPC Regulation of Transcription of HNF4A 1 0.02 0.72 0.16 58.64
35 INT276438 Binding of OPN1SW and MYP1 1 0.12 1.21 0.09 57.64
36 INT323877 LEP Positive_regulation of SOAT1 1 0.20 1.26 0.14 57.52
37 INT307219 Mlxipl Regulation of Srebf1 1 0.07 0.12 0 57.40
38 INT307216 Ppara Regulation of Srebf1 1 0.22 0.12 0 57.40
39 INT323873 LEP Regulation of Gene_expression of TIMP2 1 0.31 0.63 0.21 55.68
40 INT323884 BMI1 Regulation of Gene_expression of TIMP2 1 0.01 0.64 0.21 55.68
41 INT97795 IRF6 Positive_regulation of Localization of TNF 3 0.09 1.57 0.86 52.96
42 INT120851 NFKB1 Positive_regulation of Localization of TNF 3 0.04 2.05 0.62 52.96
43 INT295480 MAPK14 Positive_regulation of Localization of TNF 1 0.08 1.08 0.12 52.96
44 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65 52.24
45 INT122575 Akt1 Positive_regulation of Phosphorylation of Nos3 4 0.37 3.89 0.29 52.24
46 INT309889 Positive_regulation of CNR1 Positive_regulation of LPL 1 0.05 1.25 0 52.08
47 INT242035 Binding of SNRNP70 and CHDH 1 0.02 3.41 0.06 51.68
48 INT204323 Binding of ADIPOQ and Negative_regulation of Gene_expression of ROS1 1 0.08 0.12 0 50.24
49 INT295005 Binding of TNFRSF11A and Tnfsf11 3 0.20 2.02 0.09 50.00
50 INT254496 Binding of HNF4A and GOPC 1 0.10 0.34 0.08 50.00
51 INT254498 Binding of SREBF1 and GOPC 1 0.05 0.34 0.08 50.00
52 INT254495 Binding of PPARA and GOPC 1 0.04 0.34 0.08 50.00
53 INT295003 Binding of Tnfrsf11b and Tnfsf11 3 0.22 1.85 0.08 50.00
54 INT295006 Binding of TNFRSF11A and Tnfrsf11b 2 0.10 1.6 0.04 50.00
55 INT295007 Binding of DMD and Pth 1 0.00 0.07 0 50.00
56 INT295004 Binding of Pth and Tnfrsf11b 1 0.07 0.06 0 50.00
57 INT194482 Binding of Rare1 and Hdl1 1 0.00 1.73 0 49.56
58 INT115656 Glp1r Positive_regulation of Localization of Ins1 2 0.42 5.23 0.91 49.08
59 INT307213 Srebf1 Regulation of Gene_expression of Fasn 1 0.05 0.06 0 47.76
60 INT327808 EPO Regulation of VEGFA 1 0.07 1.36 0.12 47.40
61 INT329225 Prkag1 Positive_regulation of Akt1 1 0.09 1.27 0.07 46.16
62 INT204322 Binding of ADIPOQ and Positive_regulation of Gene_expression of PPARGC1A 1 0.30 0.07 0 45.76
63 INT332635 Glp1r Regulation of Localization of Gcg 1 0.03 0.94 0.04 41.80
64 INT332640 Glp1r Regulation of Localization of Ins1 1 0.04 0.52 0.04 41.80
65 INT207184 Binding of Adipoq and Lep 1 0.25 2.45 0.33 40.12
66 INT187675 DBT Positive_regulation of Gene_expression of LEP 1 0.04 0.27 0 39.08
67 INT217666 ADIPOQ Regulation of Gene_expression of INS 1 0.03 1.99 0.05 36.28
68 INT187667 DBT Positive_regulation of Localization of LEP 1 0.05 0.55 0 35.48
69 INT314624 Ex Regulation of GCG 1 0.01 0.67 0 31.28
70 INT314621 Ex Regulation of INS 1 0.06 0.67 0 30.56
71 INT212281 Vsnl1 Regulation of Ltp 1 0.00 1.32 1.07 29.28
72 INT332269 Cndp2 Negative_regulation of Tenc1 1 0.41 0.8 0.05 29.28
73 INT127966 GPT Positive_regulation of SLC17A5 1 0.50 1.81 0.14 26.72
74 INT326625 Binding of ALB and Trf 1 0.01 0.64 0.04 25.80
75 INT228984 CRP Positive_regulation of IL6 2 0.63 0.99 0.17 25.00
76 INT313554 Binding of ALOX5 and Cor 1 0.02 2.47 0.17 24.80
77 INT300488 Binding of CRP and LEP 1 0.46 2.03 0.37 19.48
78 INT332967 Atp6v1e1 Regulation of Ppara 1 0.11 0.47 0 18.60
79 INT323885 LEP Regulation of Gene_expression of NOS2 1 0.26 1.07 0.35 16.40
80 INT332964 Binding of Atp6v1e1 and Tmed4 1 0.02 0.4 0 15.40
81 INT332905 Binding of LPL and SNRNP70 1 0.01 1.34 0 14.60
82 INT332943 Binding of SNRNP70 and Adipoq 1 0.00 1.35 0 14.60
83 INT332904 Binding of LEP and SNRNP70 1 0.00 1.34 0 14.60
84 INT185359 Gpt Regulation of PCS 1 0.03 0.33 0.09 12.08
85 INT207186 Binding of Adipoq and Bmi1 1 0.01 1.65 0.18 11.28
86 INT332907 Binding of LPL and SUGT1 1 0.00 1.3 0 9.28
87 INT332965 Binding of Atp6v1e1 and Ppara 1 0.15 0.36 0 7.52
88 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12 5.00
89 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01 5.00
90 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85 5.00
91 INT319581 Binding of PIAS1 and TNFSF14 1 0.02 1.58 2.13 5.00
92 INT190524 Ros1 Positive_regulation of Nfkb1 3 0.02 4.24 2.06 5.00
93 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91 5.00
94 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
95 INT194863 Binding of IL1R1 and IL1RN 5 0.09 2.23 1.64 5.00
96 INT212287 ro Negative_regulation of Ltp 1 0.00 1.2 1.58 5.00
97 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36 5.00
98 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2 5.00
99 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11 5.00
100 INT212280 Vsnl1 Negative_regulation of Ltp 1 0.00 0.72 1.11 5.00
101 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
102 INT218310 IL6 Positive_regulation of Localization of CRP 1 0.29 3.33 1.02 5.00
103 INT81127 Binding of Gabrd and Abat 3 0.25 0 0.96 5.00
104 INT189671 DAG1 Positive_regulation of PRKCA 3 0.12 0.71 0.82 5.00
105 INT212290 Binding of Grin2a and Grin2b 2 0.20 1.36 0.82 5.00
106 INT248271 IL6 Regulation of Gene_expression of Crp 3 0.27 1.7 0.73 5.00
107 INT213026 Hdl1 Positive_regulation of Nos3 5 0.16 7.92 0.73 5.00
108 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69 5.00
109 INT278965 LEP Positive_regulation of Gene_expression of NOS2 2 0.29 2.12 0.66 5.00
110 INT45780 GNRH1 Positive_regulation of PLOD1 3 0.07 1.02 0.63 5.00
111 INT185358 Binding of MCS and PCS 7 0.22 3.34 0.57 5.00
112 INT212282 Vsnl1 Negative_regulation of Positive_regulation of Ltp 1 0.00 0.36 0.56 5.00
113 INT294708 CRP Positive_regulation of Gene_expression of VCAM1 2 0.31 1.92 0.56 5.00
114 INT212288 ro Negative_regulation of Positive_regulation of Ltp 1 0.00 0.36 0.56 5.00
115 INT209885 TNFSF11 Positive_regulation of TNFRSF11A 3 0.56 3.41 0.55 5.00
116 INT210830 OPRM1 Negative_regulation of ADCY1 1 0.00 0.06 0.55 5.00
117 INT54584 GNRH1 Positive_regulation of FSHR 3 0.48 2.02 0.54 5.00
118 INT194595 Binding of TNFSF10 and TNFRSF10B 4 0.15 9.3 0.53 5.00
119 INT348322 Il6 Positive_regulation of Localization of Crp 1 0.06 3.51 0.51 5.00
120 INT327806 Binding of ADORA1 and ADORA2A 1 0.06 0.18 0.49 5.00
121 INT341428 EPO Positive_regulation of NGF 1 0.52 0.37 0.48 5.00
122 INT341427 EPO Positive_regulation of BDNF 1 0.52 0.36 0.48 5.00
123 INT231732 Negative_regulation of Binding of Tnfrsf11a and Tnfsf11 1 0.01 1.03 0.48 5.00
124 INT231733 Binding of Tnfrsf11a and Tnfsf11 1 0.01 1.03 0.48 5.00
125 INT341426 EPO Regulation of NGF 1 0.51 0.5 0.47 5.00
126 INT341425 EPO Regulation of BDNF 1 0.51 0.5 0.47 5.00
127 INT344709 Niacr1 Positive_regulation of Hdl1 1 0.32 2.74 0.46 5.00
128 INT213027 Binding of Apoa1 and Scarb1 6 0.09 7.52 0.43 5.00
129 INT285725 Binding of IGF1R and INS 1 0.27 0.07 0.4 5.00
130 INT295478 IRF6 Positive_regulation of Positive_regulation of TLR4 2 0.20 0.78 0.39 5.00
131 INT194596 Binding of HLA-DRB4 and TNFSF10 3 0.08 6 0.38 5.00
132 INT78444 Binding of GH1 and IGF1 4 0.16 2.82 0.37 5.00
133 INT272951 Binding of TNF and Igf1 1 0.14 1.48 0.36 5.00
134 INT272953 Negative_regulation of Binding of TNF and Igf1 1 0.16 1.48 0.36 5.00
135 INT272952 Igf1 Positive_regulation of Localization of TNF 1 0.19 1.53 0.35 5.00
136 INT194865 Binding of SIGMAR1 and Positive_regulation of IL1B 1 0.01 0.62 0.35 5.00
137 INT194862 SIGMAR1 Positive_regulation of IL1B 1 0.01 0.62 0.35 5.00
138 INT253944 Positive_regulation of Prkca Positive_regulation of Gene_expression of Ins1 1 0.01 1.53 0.35 5.00
139 INT194860 BMPR2 Positive_regulation of IL1B 1 0.01 0.61 0.34 5.00
140 INT174266 TNF Regulation of Gene_expression of F3 1 0.00 3.2 0.33 5.00
141 INT89381 INS Positive_regulation of AKT1 6 0.43 3.06 0.33 5.00
142 INT230855 KNG1 Regulation of NOS1 2 0.03 0.94 0.33 5.00
143 INT194859 IL1B Positive_regulation of Gene_expression of MMP13 2 0.52 0.86 0.33 5.00
144 INT174265 IL18 Regulation of Gene_expression of F3 1 0.00 3.21 0.33 5.00
145 INT230852 ACE Regulation of KNG1 2 0.03 0.72 0.32 5.00
146 INT190683 Binding of A2M and INS 4 0.11 4.97 0.32 5.00
147 INT238895 Binding of CRP and INS 1 0.00 0.93 0.32 5.00
148 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31 5.00
149 INT344396 Ucp2 Regulation of Ros1 1 0.04 1.31 0.31 5.00
150 INT332972 Fas Positive_regulation of Ppara 1 0.17 0.52 0.31 5.00
151 INT307215 Negative_regulation of Prkca Negative_regulation of Ppara 1 0.09 0.21 0.3 5.00
152 INT194858 Binding of IL1B and SIGMAR1 1 0.01 0.55 0.3 5.00
153 INT239344 Nr1h2 Positive_regulation of Gene_expression of Srebf1 1 0.26 0.84 0.29 5.00
154 INT333886 Binding of Lep and Positive_regulation of Gene_expression of Nos2 1 0.39 0.73 0.29 5.00
155 INT333887 Binding of Lep and Positive_regulation of Gene_expression of Il1 1 0.17 0.73 0.29 5.00
156 INT239324 Nr1h2 Positive_regulation of Hltf 1 0.04 0.78 0.29 5.00
157 INT239347 Nr1h2 Positive_regulation of Srebf1 1 0.26 0.78 0.29 5.00
158 INT239329 Nr1h2 Positive_regulation of Gene_expression of Hltf 1 0.04 0.84 0.29 5.00
159 INT239336 Nr1h2 Positive_regulation of Gene_expression of Fas 1 0.07 0.84 0.29 5.00
160 INT212289 Vsnl1 Negative_regulation of Grin2a 1 0.04 0.38 0.28 5.00
161 INT344704 Positive_regulation of Ppara Positive_regulation of Binding of Hdl1 1 0.13 0.83 0.28 5.00
162 INT291641 Binding of DST and ESRRG 1 0.16 1.8 0.28 5.00
163 INT210828 POMC Positive_regulation of ADCY1 1 0.03 0.34 0.28 5.00
164 INT344715 Positive_regulation of Ppara Positive_regulation of Gene_expression of Pltp 1 0.02 0.83 0.28 5.00
165 INT295472 IRF6 Positive_regulation of Gene_expression of TNF 2 0.16 0.95 0.27 5.00
166 INT300779 STAT3 Positive_regulation of CRP 1 0.41 0.62 0.26 5.00
167 INT239335 Eef1a2 Positive_regulation of Ppara 1 0.27 0.57 0.26 5.00
168 INT300778 STAT3 Positive_regulation of Transcription of CRP 1 0.38 0.62 0.26 5.00
169 INT307207 Ppara Positive_regulation of Apoa2 1 0.10 0.94 0.25 5.00
170 INT343931 Hapln1 Negative_regulation of Tlr4 1 0.12 0.42 0.25 5.00
171 INT309888 INS Positive_regulation of Gene_expression of FAAH 1 0.04 1.19 0.25 5.00
172 INT239337 Abca1 Positive_regulation of RCT 1 0.07 3.11 0.24 5.00
173 INT344714 Nr1h4 Negative_regulation of Gene_expression of Lipg 1 0.02 0.77 0.23 5.00
174 INT179492 Binding of Ins1 and Adipoq 1 0.16 1.16 0.23 5.00
175 INT306795 Binding of LEP and SFTPD 1 0.08 1.13 0.23 5.00
176 INT265886 IGF1 Positive_regulation of AKT1 1 0.11 3.06 0.23 5.00
177 INT207845 Binding of INS and Hypism 3 0.04 2.88 0.22 5.00
178 INT312517 Rapgef1 Negative_regulation of Rbp4 1 0.01 0.9 0.22 5.00
179 INT311872 IGHE Positive_regulation of Localization of Mmp9 1 0.01 1.35 0.22 5.00
180 INT339903 Binding of SCN5A and ZGLP1 1 0.01 0.18 0.22 5.00
181 INT207185 Binding of Bmi1 and Lep 1 0.01 1.7 0.21 5.00
182 INT344398 Nfkb1 Positive_regulation of Gene_expression of IL6 1 0.12 0.56 0.21 5.00
183 INT313498 Binding of ALOX5 and SNRNP70 1 0.05 2.7 0.21 5.00
184 INT189321 Binding of Apoa1 and Hdlcl1 1 0.00 0.68 0.2 5.00
185 INT344399 IL8 Regulation of Gene_expression of Crp 1 0.03 0.59 0.2 5.00
186 INT239328 Hdl1 Regulation of Gene_expression of Kitl 1 0.08 1.86 0.2 5.00
187 INT339901 Binding of INS and SCN5A 1 0.01 0.18 0.2 5.00
188 INT333889 Lep Regulation of Col7a1 1 0.04 0.41 0.2 5.00
189 INT352518 Binding of FAT1 and Adipoq 1 0.01 2.79 0.2 5.00
190 INT336379 TIMP1 Negative_regulation of FADS1 1 0.01 0.52 0.2 5.00
191 INT327814 Rab8a Regulation of Regulation of Lep 1 0.01 0.15 0.19 5.00
192 INT327813 Rab8a Regulation of Lep 1 0.01 0.15 0.19 5.00
193 INT291642 Binding of DST and GGT1 1 0.00 1.4 0.19 5.00
194 INT265048 INCENP Positive_regulation of Positive_regulation of Nfasc 1 0.00 0.69 0.19 5.00
195 INT333888 Lep Regulation of Localization of GAG 1 0.68 0.38 0.19 5.00
196 INT316203 Ghsr Positive_regulation of Transcription of Agrp 1 0.02 1.5 0.19 5.00
197 INT242037 Binding of CRP and SNRNP70 3 0.07 4.62 0.19 5.00
198 INT217661 LEP Positive_regulation of INS 2 0.25 1.85 0.19 5.00
199 INT264189 HR Positive_regulation of Gene_expression of IL10 1 0.00 1.48 0.19 5.00
200 INT217665 ADIPOQ Positive_regulation of INS 2 0.06 1.8 0.19 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Overweight. They are ordered first by their pain relevance and then by number of times they were reported in Overweight. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT1026 Binding of Lbp 207 0.48 150.96 119.16 100.00
2 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95 100.00
3 INT172171 Gene_expression of IL15 47 0.37 46.23 13.41 100.00
4 INT172186 Gene_expression of IL6ST 20 0.75 11.63 2.67 100.00
5 INT254505 Gene_expression of IL17D 1 0.35 1.83 0.13 100.00
6 INT94429 Transcription of TIMP2 3 0.61 4.05 0.67 100.00
7 INT94430 Positive_regulation of Transcription of TIMP2 2 0.24 2.25 0.39 100.00
8 INT103487 Positive_regulation of Positive_regulation of Lep 9 0.67 4.08 2.38 100.00
9 INT4535 Localization of PROC 106 0.73 76.24 21.1 100.00
10 INT323894 Negative_regulation of Regulation of TIMP2 1 0.20 1.04 0.23 100.00
11 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.84
12 INT251 Regulation of INS 398 0.62 232.47 55.04 99.84
13 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 99.84
14 INT37800 Positive_regulation of Apob 7 0.18 11.01 0.48 99.84
15 INT3486 Positive_regulation of Regulation of INS 9 0.47 5.65 1.15 99.84
16 INT213399 Negative_regulation of SELPLG 3 0.16 3.23 0.03 99.84
17 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 99.84
18 INT117731 Binding of MYP1 7 0.30 10.61 0.67 99.76
19 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 99.74
20 INT204366 Positive_regulation of Gene_expression of PPARGC1A 1 0.67 1.44 0 99.74
21 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 99.64
22 INT220928 Positive_regulation of Transcription of MMP13 4 0.47 1.93 0.33 99.58
23 INT220926 Transcription of MMP13 12 0.67 3.03 1.09 99.58
24 INT344695 Positive_regulation of Tgs1 1 0.02 1.86 0 99.58
25 INT75908 Regulation of LEP 77 0.60 60.16 15.19 99.52
26 INT241191 Positive_regulation of Kctd1 2 0.06 4.28 0.16 99.50
27 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 99.48
28 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 99.48
29 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62 99.46
30 INT170854 Gene_expression of CFD 26 0.68 39.77 4.74 99.46
31 INT90406 Gene_expression of IL6R 27 0.38 15.74 3.64 99.46
32 INT221056 Gene_expression of IL10RA 3 0.38 3.26 0.34 99.46
33 INT82079 Positive_regulation of Lep 79 0.70 40 11.07 99.46
34 INT82077 Positive_regulation of Gene_expression of Lep 32 0.70 17.9 3.5 99.46
35 INT134798 Gene_expression of ANXA1 15 0.75 13.94 2.99 99.44
36 INT15543 Gene_expression of CASP8 32 0.75 25.6 2.61 99.44
37 INT123779 Positive_regulation of MMP13 42 0.65 24.3 12.45 99.40
38 INT315760 Positive_regulation of PXDNL 1 0.01 0.92 0.03 99.40
39 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 99.28
40 INT67612 Binding of PPARG 38 0.48 22.67 8.94 99.28
41 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76 99.26
42 INT346663 Binding of FAT1 1 0.04 0.48 0 99.24
43 INT197513 Transcription of ABCA4 2 0.43 0.86 0 99.20
44 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 99.18
45 INT7475 Positive_regulation of Hdl1 138 0.67 175.81 15.05 99.16
46 INT171712 Negative_regulation of FAT1 19 0.15 6.57 0.23 99.10
47 INT169592 Localization of FAT1 3 0.51 3.21 0.91 99.10
48 INT249049 Positive_regulation of ARID1B 14 0.56 24.77 0.71 99.10
49 INT18639 Positive_regulation of OAP 16 0.69 10.49 4.57 99.08
50 INT101912 Regulation of TIMP2 8 0.44 5.55 2 99.04
51 INT204348 Gene_expression of PPARGC1A 10 0.75 2.73 0.19 99.02
52 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22 99.00
53 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04 98.96
54 INT129956 Gene_expression of MMP13 145 0.72 60.48 26.98 98.96
55 INT290263 Transcription of FAT1 2 0.62 1.23 0 98.96
56 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 98.96
57 INT129962 Positive_regulation of Gene_expression of MMP13 41 0.65 20.74 8.54 98.96
58 INT17686 Negative_regulation of Hdl1 72 0.36 81.85 7.74 98.92
59 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 98.88
60 INT10863 Positive_regulation of Ldlr 45 0.68 31.06 7.05 98.84
61 INT127145 Gene_expression of SET 46 0.65 10.39 1.7 98.80
62 INT89181 Gene_expression of Mc3r 33 0.77 22.48 11.85 98.78
63 INT28486 Positive_regulation of Phdlc1 18 0.40 14.4 2.17 98.76
64 INT159472 Localization of NPPB 32 0.79 33.67 3.59 98.76
65 INT180036 Positive_regulation of D7Cwr3P 2 0.03 4.58 0.54 98.76
66 INT32795 Positive_regulation of Hypism 17 0.15 20.16 1.73 98.76
67 INT93664 Gene_expression of TIMP2 33 0.67 36.67 7.14 98.72
68 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 98.72
69 INT4146 Binding of SHBG 49 0.47 31 4.71 98.72
70 INT10445 Transcription of CNR1 16 0.68 6.75 6.4 98.60
71 INT132867 Negative_regulation of Transcription of CNR1 3 0.41 2.23 0.55 98.60
72 INT11030 Binding of LPA 70 0.48 40.35 4.81 98.56
73 INT9650 Gene_expression of LPA 141 0.75 104.57 29 98.48
74 INT171252 Gene_expression of BMI1 21 0.70 26.98 4.11 98.40
75 INT11823 Positive_regulation of GGT1 53 0.67 45.84 7.55 98.40
76 INT52508 Positive_regulation of TIMP2 7 0.43 8.1 1.96 98.36
77 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32 98.36
78 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 98.36
79 INT318819 Positive_regulation of Transcription of IGF1 1 0.33 1.94 0.07 98.36
80 INT66709 Transcription of IGF1 13 0.71 5.65 1.64 98.36
81 INT144097 Negative_regulation of Hypism 4 0.18 2.88 0.3 98.36
82 INT171254 Binding of OAP 7 0.39 8.04 3.42 98.34
83 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 98.20
84 INT9649 Positive_regulation of LPA 105 0.69 74.75 13.89 98.16
85 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 98.12
86 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 98.12
87 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94 98.08
88 INT52350 Gene_expression of CD14 184 0.75 71.37 33.13 98.04
89 INT49473 Gene_expression of MSR1 14 0.75 7.28 2.64 98.04
90 INT49437 Gene_expression of OAP 25 0.54 20.12 7.34 98.02
91 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31 97.96
92 INT171253 Positive_regulation of BMI1 23 0.53 39.41 11.23 97.96
93 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17 97.96
94 INT108588 Gene_expression of CASP3 126 0.78 84.49 16.2 97.76
95 INT36400 Regulation of SCN10A 7 0.62 2.73 1.97 97.74
96 INT195206 Binding of BCC1 15 0.41 21.3 0.62 97.68
97 INT10442 Negative_regulation of CNR1 47 0.59 20.88 20.2 97.64
98 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2 97.48
99 INT229750 Positive_regulation of Gene_expression of CHDH 9 0.30 9.38 0.03 97.48
100 INT204332 Positive_regulation of PPARGC1A 7 0.67 1.42 0.07 97.40
101 INT204367 Positive_regulation of SIRT1 13 0.68 4.17 0 97.40
102 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 97.36
103 INT290040 Gene_expression of C8G 1 0.01 0.99 0 97.32
104 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 97.28
105 INT812 Localization of INS 1026 0.81 515.6 145.31 97.20
106 INT73784 Regulation of Binding of GH1 2 0.26 0.82 0.86 97.20
107 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 97.20
108 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79 97.20
109 INT123466 Binding of T2dm2 21 0.37 34.87 2.91 97.20
110 INT345961 Negative_regulation of D0Ffm3 1 0.03 3.73 0.07 97.12
111 INT341638 Binding of Arid1a 2 0.09 4.25 0.04 97.08
112 INT178888 Gene_expression of CHDH 41 0.65 38.66 2.51 97.00
113 INT8340 Negative_regulation of SHBG 49 0.57 35.96 4.73 97.00
114 INT155867 Transcription of COL1A2 8 0.69 2.9 0.94 97.00
115 INT290265 Positive_regulation of FAT1 11 0.67 5.93 0.91 96.92
116 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 96.84
117 INT3315 Negative_regulation of Positive_regulation of INS 31 0.57 14.73 2.27 96.84
118 INT21775 Gene_expression of crf 8 0.54 4.96 2.7 96.84
119 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 96.76
120 INT38987 Protein_catabolism of INS 21 0.99 11.92 2.91 96.76
121 INT109104 Positive_regulation of Protein_catabolism of INS 4 0.50 4.44 1.24 96.76
122 INT119606 Regulation of Gene_expression of LEP 17 0.45 17.96 3.75 96.72
123 INT290039 Gene_expression of DDX12P 1 0.00 1.41 0 96.68
124 INT204351 Negative_regulation of PPARGC1A 1 0.42 0.25 0 96.62
125 INT5793 Binding of CTS 110 0.48 63.91 40.62 96.60
126 INT197512 Gene_expression of ABCA4 19 0.75 7.08 0.57 96.56
127 INT215863 Positive_regulation of Ex 3 0.16 2.46 0 96.52
128 INT149332 Gene_expression of CD163 19 0.75 13.63 3.65 96.48
129 INT9660 Regulation of TNF 363 0.62 312.94 139.99 96.44
130 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 96.36
131 INT204361 Negative_regulation of SIRT1 1 0.42 0.18 0 96.36
132 INT79691 Regulation of Gene_expression of PPARG 10 0.50 10.44 1.62 96.16
133 INT222897 Regulation of Gene_expression of SNRNP70 5 0.44 1.44 0.13 96.16
134 INT35486 Regulation of PTGER2 39 0.36 19.03 6.75 96.00
135 INT323897 Positive_regulation of Gene_expression of BMI1 2 0.22 3.8 0.17 95.96
136 INT18636 Negative_regulation of OAP 9 0.37 5.05 2.13 95.92
137 INT213277 Positive_regulation of Gene_expression of ADIPOQ 14 0.50 17.7 1.14 95.76
138 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 95.76
139 INT41986 Positive_regulation of Gene_expression of HSD11B1 26 0.49 32.84 1.52 95.76
140 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 95.72
141 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 95.72
142 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 95.64
143 INT209336 Gene_expression of Filipino 5 0.10 4.75 1.2 95.60
144 INT79690 Negative_regulation of Gene_expression of PPARG 10 0.59 10.48 1.55 95.52
145 INT290037 Negative_regulation of Gene_expression of SNRNP70 4 0.07 3.64 0.45 95.52
146 INT271327 Gene_expression of PCNT 3 0.62 0.7 0.49 95.48
147 INT39457 Positive_regulation of SOAT1 32 0.67 22.8 8.28 95.40
148 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 95.36
149 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 95.28
150 INT9683 Binding of GH1 57 0.47 21.14 5.99 95.24
151 INT82913 Regulation of Ppara 15 0.61 10.66 3.03 95.24
152 INT148702 Positive_regulation of UPF1 29 0.31 12.9 1.91 95.16
153 INT5298 Negative_regulation of MTHFS 70 0.57 27.07 28.11 95.16
154 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42 95.12
155 INT122812 Gene_expression of SNRNP70 130 0.75 67 12.5 95.12
156 INT122041 Binding of Ppara 308 0.48 189.17 51.48 95.04
157 INT182800 Positive_regulation of ETV3 5 0.46 10.01 0.14 94.96
158 INT1721 Negative_regulation of HP 148 0.42 86.82 16.89 94.92
159 INT28151 Positive_regulation of CTs 55 0.61 35.09 20.14 94.72
160 INT162006 Positive_regulation of Gene_expression of ASAP1 7 0.44 3.3 0.13 94.72
161 INT165228 Binding of BMI1 13 0.47 25.36 7.97 94.68
162 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29 94.60
163 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 94.56
164 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95 94.52
165 INT55002 Gene_expression of ASAP1 46 0.64 22.8 3.2 94.48
166 INT22907 Positive_regulation of Ggt1 33 0.67 17.82 5.28 94.44
167 INT1027 Gene_expression of Lbp 132 0.77 106.7 54.16 94.40
168 INT207183 Binding of Bmi1 1 0.01 16.24 1.14 94.38
169 INT207568 Negative_regulation of VAT1 1 0.13 8.92 0.55 94.32
170 INT28739 Binding of Ins1 35 0.37 22.43 2.14 94.32
171 INT24332 Regulation of Hdl1 28 0.45 45.45 4.26 94.20
172 INT94454 Gene_expression of CD68 73 0.72 63.94 10.43 94.16
173 INT263523 Regulation of Binding of BMI1 1 0.34 3.01 1.3 94.16
174 INT17086 Binding of HSD11B1 84 0.47 122.28 6.16 94.12
175 INT216873 Binding of TBL1XR1 3 0.36 4.44 0.4 94.12
176 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 94.08
177 INT47994 Negative_regulation of Lipg 45 0.50 27.19 7.24 94.08
178 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 93.84
179 INT8798 Positive_regulation of Csrp1 61 0.69 63.86 14.14 93.84
180 INT69436 Negative_regulation of Gene_expression of ROS1 81 0.38 46.58 12.22 93.84
181 INT190031 Binding of Scrib 19 0.36 21.9 1.01 93.84
182 INT16165 Regulation of DMD 114 0.60 35.13 3.64 93.80
183 INT16618 Negative_regulation of SERPING1 81 0.59 86.28 7.17 93.80
184 INT182787 Binding of ETV3 14 0.37 25.44 0.37 93.68
185 INT323229 Positive_regulation of Tgs1 2 0.17 4.63 0.23 93.44
186 INT38056 Localization of Crp 71 0.78 53.14 17.03 93.36
187 INT290870 Negative_regulation of MNT 1 0.05 1.61 0 93.36
188 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41 93.20
189 INT83433 Positive_regulation of ADIPOQ 40 0.69 34 3.67 93.12
190 INT169591 Gene_expression of FAT1 23 0.67 10.73 0.77 93.04
191 INT332613 Positive_regulation of Protein_catabolism of Glp1r 1 0.09 1.55 0.11 93.04
192 INT187618 Localization of Ppara 13 0.70 6.91 3.09 92.96
193 INT84375 Regulation of COL1A2 6 0.44 8.75 1.72 92.80
194 INT150384 Binding of RCT 10 0.25 3.1 2.05 92.80
195 INT9664 Binding of LBP 127 0.48 94.9 63.42 92.64
196 INT3213 Gene_expression of Ins1 511 0.76 357.59 53.32 92.64
197 INT69486 Negative_regulation of Bcl2a1c 34 0.10 19.03 0.6 92.40
198 INT217685 Negative_regulation of BMI1 7 0.18 6.01 0.82 92.28
199 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75 92.28
200 INT332612 Protein_catabolism of Glp1r 1 0.18 3.56 0.38 92.28
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