D:Pancreatic Cyst

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Disease Term
Synonyms Cyst Pancreatic, Cysts Pancreatic, Pancreatic Cysts
Documents 116
Hot Single Events 22
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Pancreatic Cyst. They are ordered first by their relevance to Pancreatic Cyst and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT187388 Esr2 Positive_regulation of Gene_expression of Pgr 1 0.00 0.8 0.03 24.16
2 INT241248 Binding of Pkd1 and Pkd2 3 0.22 1.52 0.1 5.00
3 INT286568 Car2 Positive_regulation of Positive_regulation of Pkd1 1 0.03 0.16 0.09 5.00
4 INT286565 Pkd2 Positive_regulation of Positive_regulation of Pkd1 1 0.21 0.11 0.09 5.00
5 INT286592 Binding of PKD1 and P1Ehs1 1 0.00 0.16 0.06 5.00
6 INT286563 Binding of Id2 and P1Ehs1 1 0.00 0.17 0.06 5.00
7 INT286591 Binding of PKD1 and Id2 1 0.07 0.17 0.06 5.00
8 INT241120 Binding of Sdhc and Sdhd 1 0.00 1.28 0 5.00
9 INT286566 Binding of Ctnnb1 and Cdh6 1 0.00 1 0 5.00
10 INT286562 Gene_expression of Pkd1 Positive_regulation of Ctnnb1 1 0.02 0.52 0 5.00
11 INT286571 Binding of Prkd1 and Pkd1 1 0.05 0.76 0 5.00
12 INT241119 Binding of Sdhc and Sdhb 1 0.00 1.29 0 5.00
13 INT286574 Gene_expression of Pkd1 Negative_regulation of Cdk2 1 0.10 0.09 0 5.00
14 INT286570 Pkd2 Positive_regulation of Binding of Pkd1 1 0.21 0.73 0 5.00
15 INT286501 Binding of PKD1 and LILRB1 1 0.01 1.07 0 5.00
16 INT286561 Binding of Ctnnb1 and Cdh2 1 0.00 1.06 0 5.00
17 INT286593 Binding of Pkd1 and GOPC 1 0.02 1.13 0 5.00
18 INT286589 Binding of PKHD1 and Pkd2 1 0.09 0.52 0 5.00
19 INT286567 Prkd1 Regulation of Ctnnb1 1 0.01 0.39 0 5.00
20 INT286573 Pkd2 Regulation of Pkd1 1 0.12 0.25 0 5.00
21 INT286564 Pkd1 Regulation of Mtor 1 0.00 0.51 0 5.00
22 INT286569 Binding of Pkd1 and Tsc2 1 0.06 1.01 0 5.00
23 INT286590 Binding of ID2 and Pkd2 1 0.13 0.13 0 5.00
24 INT286572 Binding of Ctnnb1 and Pkd1 1 0.02 0.96 0 5.00
25 INT286594 Binding of LILRB1 and Pkd1 1 0.01 1.07 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Pancreatic Cyst. They are ordered first by their pain relevance and then by number of times they were reported in Pancreatic Cyst. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT138440 Gene_expression of Spt 4 0.47 4.94 0.5 99.20
2 INT14485 Positive_regulation of Cela1 15 0.44 10.55 3.01 99.02
3 INT271915 Negative_regulation of Pkd1 8 0.36 6.44 0 97.00
4 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 95.28
5 INT17736 Gene_expression of Cfp 111 0.65 40.68 36.61 95.08
6 INT68564 Binding of Fap 6 0.32 6.75 0.65 94.96
7 INT24439 Gene_expression of Spink1 19 0.63 10.05 4.35 94.52
8 INT812 Localization of INS 1026 0.81 515.6 145.31 94.24
9 INT100375 Gene_expression of Vhl 14 0.15 22.3 1.69 93.24
10 INT100376 Positive_regulation of Gene_expression of Vhl 4 0.10 6.47 1.47 93.24
11 INT241117 Regulation of Gene_expression of Vhl 1 0.06 2.5 0.07 93.24
12 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01 93.12
13 INT241241 Positive_regulation of Gene_expression of Pkd2 3 0.50 1.3 0.03 90.32
14 INT42039 Positive_regulation of Spink1 11 0.67 8.4 2.48 90.00
15 INT241243 Gene_expression of Pkd2 30 0.77 9.05 0.53 89.68
16 INT23177 Negative_regulation of Gene_expression of HLA-DRA 50 0.44 16.99 10.55 86.00
17 INT212176 Gene_expression of CEACAM5 7 0.75 6.05 0.24 84.96
18 INT35328 Gene_expression of KRTAP19-9P 9 0.52 9.08 1.44 84.64
19 INT68665 Binding of Vhl 9 0.48 10.3 0.82 81.60
20 INT63701 Localization of KRIT1 11 0.78 2.02 9.17 81.48
21 INT179888 Localization of KRT7 3 0.39 2.85 0.22 80.80
22 INT214630 Localization of KRT10 1 0.73 0.56 0 80.20
23 INT100622 Localization of CD68 16 0.73 6.58 2.2 76.72
24 INT70021 Localization of BCL2 23 0.74 21.6 1.09 76.72
25 INT87819 Localization of CD34 21 0.81 7.69 0.47 76.72
26 INT134223 Localization of CD99 4 0.73 4.42 0.16 76.72
27 INT210430 Gene_expression of Arl3 1 0.55 1.85 0.12 75.96
28 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 75.00
29 INT27660 Binding of CFP 21 0.40 12.47 3.51 75.00
30 INT241118 Negative_regulation of Vhl 3 0.11 4.01 0.08 71.48
31 INT71019 Negative_regulation of SMAD4 12 0.42 6.88 0.43 67.28
32 INT3755 Positive_regulation of GBE1 29 0.40 8.99 8.91 66.72
33 INT286532 Localization of Prkd1 3 0.58 3.02 0.16 64.84
34 INT1939 Localization of Cys1 6 0.73 5.9 0.64 64.32
35 INT286540 Localization of Btk 1 0.28 1.26 0 64.12
36 INT286544 Localization of Ift88 1 0.52 1.26 0 63.80
37 INT30075 Localization of Esr2 2 0.01 0.78 0.49 46.64
38 INT286538 Gene_expression of Prkd1 7 0.56 3.97 0.24 40.72
39 INT31757 Negative_regulation of Egf 18 0.41 9.7 2.94 36.32
40 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 27.04
41 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 27.04
42 INT65545 Localization of EGFR 35 0.79 20.8 1.88 27.04
43 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19 22.24
44 INT241100 Negative_regulation of Binding of FH 1 0.11 2.76 0.05 14.80
45 INT152215 Binding of FH 10 0.41 14.13 0.19 13.04
46 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 9.92
47 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
48 INT397 Localization of SST 232 0.81 58.05 101.19 5.00
49 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35 5.00
50 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 5.00
51 INT30170 Gene_expression of Car2 330 0.66 77.26 46.76 5.00
52 INT17561 Localization of Car2 303 0.79 60.95 44.52 5.00
53 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
54 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 5.00
55 INT70437 Negative_regulation of Mdk 115 0.57 41.03 35.72 5.00
56 INT22708 Gene_expression of MUC1 297 0.78 232.71 24.19 5.00
57 INT12243 Positive_regulation of PRSS1 91 0.70 52.87 19.48 5.00
58 INT98647 Positive_regulation of Mdk 65 0.59 32.93 15.67 5.00
59 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 5.00
60 INT66611 Localization of Cfp 22 0.65 7.04 14.64 5.00
61 INT170601 Positive_regulation of Gene_expression of GOPC 122 0.43 42.79 11.68 5.00
62 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63 5.00
63 INT15888 Positive_regulation of Nbr1 42 0.69 35.76 10.48 5.00
64 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 5.00
65 INT6511 Positive_regulation of AFP 76 0.70 70.15 7.28 5.00
66 INT9397 Regulation of MET 17 0.60 8.36 7.04 5.00
67 INT24042 Gene_expression of MUC5AC 98 0.77 74.99 6.18 5.00
68 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22 5.00
69 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19 5.00
70 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91 5.00
71 INT104182 Gene_expression of ABCC2 19 0.76 5.92 2.88 5.00
72 INT4686 Gene_expression of Cys1 32 0.66 36.24 2.49 5.00
73 INT174979 Phosphorylation of GOPC 45 0.51 10.11 2.28 5.00
74 INT67190 Gene_expression of Muc2 24 0.78 18.8 2.08 5.00
75 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97 5.00
76 INT220177 Binding of Apc 21 0.37 15.34 1.37 5.00
77 INT152951 Negative_regulation of LEF1 5 0.41 3.22 1.31 5.00
78 INT110434 Positive_regulation of Gene_expression of Apc 20 0.50 11.37 1.3 5.00
79 INT139237 Negative_regulation of Gene_expression of CDH1 23 0.57 24.31 1.28 5.00
80 INT188396 Positive_regulation of Positive_regulation of GOPC 13 0.42 1.78 1.21 5.00
81 INT157765 Negative_regulation of CDH1 32 0.53 35.72 1.15 5.00
82 INT68565 Gene_expression of Fap 14 0.57 24.39 1.14 5.00
83 INT86889 Gene_expression of Cdx2 8 0.60 4.23 1.02 5.00
84 INT151774 Positive_regulation of Mtor 38 0.45 20.15 1.01 5.00
85 INT124850 Gene_expression of Tpt1 42 0.77 14.51 0.79 5.00
86 INT134207 Gene_expression of Ptk2 56 0.73 31.97 0.78 5.00
87 INT114880 Negative_regulation of Cdk2 7 0.35 3.89 0.77 5.00
88 INT129174 Gene_expression of PKD1 24 0.67 14.91 0.74 5.00
89 INT137850 Gene_expression of PKD2 9 0.65 6.68 0.63 5.00
90 INT215183 Positive_regulation of MUC5AC 4 0.45 2.78 0.6 5.00
91 INT36702 Gene_expression of CEACAM3 4 0.68 4.56 0.58 5.00
92 INT241235 Binding of Pkd2 11 0.48 2.43 0.55 5.00
93 INT77887 Negative_regulation of Spt 7 0.50 3.9 0.54 5.00
94 INT134208 Negative_regulation of Ptk2 19 0.58 23.59 0.52 5.00
95 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47 5.00
96 INT286550 Negative_regulation of Prkd1 4 0.42 3.68 0.45 5.00
97 INT23650 Positive_regulation of Sdhb 2 0.17 1.34 0.43 5.00
98 INT76958 Positive_regulation of Ctnnb1 14 0.64 5.48 0.41 5.00
99 INT150826 Positive_regulation of Pkd1 9 0.37 3.65 0.35 5.00
100 INT283683 Binding of Id2 5 0.35 0.8 0.35 5.00
101 INT225667 Transcription of Apc 3 0.52 3.73 0.32 5.00
102 INT226835 Gene_expression of Cdh2 14 0.22 8.04 0.31 5.00
103 INT241104 Gene_expression of FH 7 0.66 20.35 0.31 5.00
104 INT241240 Gene_expression of Pkd1 18 0.54 12.2 0.27 5.00
105 INT241238 Positive_regulation of Pkd2 5 0.46 1.44 0.24 5.00
106 INT99176 Positive_regulation of Fap 4 0.13 7.5 0.22 5.00
107 INT282798 Binding of Prkd1 2 0.18 2.11 0.19 5.00
108 INT208476 Binding of Pkd1 13 0.39 7.23 0.17 5.00
109 INT230524 Binding of LILRB1 2 0.35 2.14 0.15 5.00
110 INT139331 Localization of Vhl 2 0.65 2.34 0.15 5.00
111 INT286548 Positive_regulation of Prkd1 7 0.36 4.35 0.15 5.00
112 INT241102 Transcription of FH 2 0.59 2 0.14 5.00
113 INT212175 Positive_regulation of Gene_expression of CEACAM5 1 0.36 0.7 0.13 5.00
114 INT212174 Positive_regulation of CEACAM5 1 0.34 0.69 0.12 5.00
115 INT271941 Binding of Tsc2 12 0.24 2.96 0.11 5.00
116 INT241099 Positive_regulation of Gene_expression of FH 3 0.43 5.17 0.11 5.00
117 INT283708 Localization of Id2 2 0.71 0.72 0.11 5.00
118 INT241115 Regulation of Vhl 5 0.15 8.36 0.11 5.00
119 INT242819 Negative_regulation of Gene_expression of Apc 4 0.37 5.6 0.1 5.00
120 INT283560 Negative_regulation of Gene_expression of Ptk2 6 0.40 4.84 0.09 5.00
121 INT85280 Positive_regulation of FH 2 0.45 3.53 0.09 5.00
122 INT140494 Negative_regulation of Fap 3 0.37 2.3 0.08 5.00
123 INT286583 Localization of PKD2 1 0.35 0.17 0.06 5.00
124 INT235057 Positive_regulation of Negative_regulation of Apc 2 0.30 0.66 0.05 5.00
125 INT211006 Binding of PKD1 6 0.22 2.69 0.05 5.00
126 INT241114 Transcription of Vhl 1 0.11 2.3 0.05 5.00
127 INT286547 Negative_regulation of Kif3a 1 0.15 0.48 0.05 5.00
128 INT286535 Regulation of Prkd1 3 0.33 2.24 0.04 5.00
129 INT247803 Positive_regulation of Cdh2 2 0.11 2.03 0.04 5.00
130 INT176573 Positive_regulation of Esr2 2 0.01 1.43 0.04 5.00
131 INT286543 Localization of Pkd1 5 0.52 3.74 0.04 5.00
132 INT238180 Binding of Ptk2 5 0.35 2.99 0.04 5.00
133 INT286581 Gene_expression of PKHD1 1 0.24 0.19 0.03 5.00
134 INT286533 Negative_regulation of Gene_expression of Cdh2 1 0.11 1.4 0.03 5.00
135 INT282568 Positive_regulation of Cdk2 6 0.34 2.95 0.03 5.00
136 INT241113 Negative_regulation of Binding of Vhl 1 0.07 3.31 0.03 5.00
137 INT286580 Positive_regulation of Gene_expression of PKHD1 1 0.16 0.1 0.03 5.00
138 INT286551 Binding of Pxn 1 0.08 0.94 0 5.00
139 INT286556 Binding of Neat1 1 0.05 0.94 0 5.00
140 INT242821 Negative_regulation of Localization of Fap 1 0.11 1.91 0 5.00
141 INT242822 Transcription of Fap 1 0.18 1.2 0 5.00
142 INT286582 Localization of BBS1 1 0.02 0.74 0 5.00
143 INT286577 Binding of ID2 1 0.19 0.12 0 5.00
144 INT286555 Binding of Ift88 1 0.30 0.08 0 5.00
145 INT286588 Positive_regulation of Localization of PKHD1 1 0.16 0.79 0 5.00
146 INT258949 Localization of OFD1 2 0.41 3.87 0 5.00
147 INT241106 Localization of FH 1 0.20 2.1 0 5.00
148 INT283691 Binding of Aatf 2 0.03 0.19 0 5.00
149 INT286541 Negative_regulation of Cdh2 1 0.03 1.09 0 5.00
150 INT242820 Localization of Fap 1 0.20 1.9 0 5.00
151 INT286545 Positive_regulation of Gene_expression of Pkd1 1 0.42 1.55 0 5.00
152 INT286576 Binding of PKHD1 1 0.12 0.63 0 5.00
153 INT286558 Transcription of Nek8 1 0.46 0.7 0 5.00
154 INT286539 Localization of Nek8 1 0.57 0.73 0 5.00
155 INT286552 Positive_regulation of Localization of Nek8 1 0.38 0.73 0 5.00
156 INT286549 Regulation of Tsc2 1 0.11 0.42 0 5.00
157 INT286578 Localization of ALMS1 1 0.22 0.75 0 5.00
158 INT271919 Gene_expression of Tsc2 6 0.39 2.23 0 5.00
159 INT286557 Regulation of Binding of Aatf 1 0.02 0 0 5.00
160 INT120527 Localization of ABCC2 3 0.78 1.03 0 5.00
161 INT286585 Positive_regulation of Localization of ALMS1 1 0.15 0.75 0 5.00
162 INT286542 Binding of Vcl 1 0.04 0.94 0 5.00
163 INT241107 Negative_regulation of Transcription of FLCN 1 0.02 2.38 0 5.00
164 INT215181 Binding of Muc2 1 0.17 0.77 0 5.00
165 INT286537 Gene_expression of Cdh6 1 0.04 0.98 0 5.00
166 INT150827 Regulation of Pkd1 4 0.32 2.18 0 5.00
167 INT286554 Negative_regulation of Gene_expression of Pkd1 1 0.35 1.77 0 5.00
168 INT286534 Negative_regulation of Gene_expression of Prkd1 2 0.31 0.89 0 5.00
169 INT286586 Positive_regulation of Localization of OFD1 1 0.12 0.74 0 5.00
170 INT241116 Negative_regulation of Localization of Vhl 1 0.06 2.23 0 5.00
171 INT286587 Negative_regulation of LAMA3 1 0.01 1.01 0 5.00
172 INT286559 Positive_regulation of Gene_expression of Cdh2 1 0.04 1.04 0 5.00
173 INT286584 Positive_regulation of PKHD1 1 0.13 1.01 0 5.00
174 INT286536 Positive_regulation of Positive_regulation of Prkd1 1 0.08 1.28 0 5.00
175 INT241103 Transcription of FLCN 1 0.04 2.36 0 5.00
176 INT241108 Binding of FLCN 2 0.31 7.33 0 5.00
177 INT241105 Gene_expression of FLCN 3 0.65 15.31 0 5.00
178 INT329927 Localization of Spt 1 0.61 1.39 0 5.00
179 INT242823 Binding of CTNND2 1 0.36 6 0 5.00
180 INT283566 Localization of Ptk2 5 0.75 0.93 0 5.00
181 INT169921 Negative_regulation of Gene_expression of Tpt1 3 0.25 1.38 0 5.00
182 INT286579 Localization of PKHD1 1 0.24 0.79 0 5.00
183 INT286553 Transcription of Prkd1 1 0.12 0.7 0 5.00
184 INT286546 Negative_regulation of Gene_expression of Pkd2 2 0.27 0.57 0 5.00
185 INT241101 Negative_regulation of Gene_expression of FH 2 0.42 3.16 0 5.00
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