D:Papilloma

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Disease Term
Synonyms Papilloma Squamous Cell, Papillomas, PAPILLOMAS SQUAMOUS CELL, Papillomatoses, Papillomatosis, SQUAMOUS CELL PAPILLOMA, Squamous Cell Papillomas
Documents 111
Hot Single Events 15
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Papilloma. They are ordered first by their relevance to Papilloma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT304029 Binding of PTEN and TP53 1 0.35 0.62 0 5.00
2 INT304020 AR Regulation of TP53 1 0.24 1.11 0 5.00
3 INT304022 Binding of PIK3CG and TP53 1 0.10 0.72 0 5.00
4 INT304028 MDM2 Regulation of TP53 1 0.19 1.11 0 5.00
5 INT304014 Binding of MSI1 and SGCG 1 0.00 1.92 0 5.00
6 INT304012 Binding of AKT1 and PIK3CA 1 0.28 1.14 0 5.00
7 INT304018 Regulation of Binding of PIK3CG and TP53 1 0.12 0.73 0 5.00
8 INT304025 Binding of PIK3CA and TP53 1 0.30 0.67 0 5.00
9 INT304015 Binding of PIK3CA and PIK3CG 1 0.09 0.67 0 5.00
10 INT304019 Binding of AKT1 and TP53 1 0.27 0.72 0 5.00
11 INT304026 Binding of PIK3CG and PTEN 1 0.11 0.62 0 5.00
12 INT304027 Negative_regulation of PTEN Positive_regulation of Positive_regulation of AKT1 1 0.32 1.86 0 5.00
13 INT304017 Regulation of Binding of AKT1 and TP53 1 0.32 0.73 0 5.00
14 INT304023 SFRP1 Regulation of Binding of MSI1 1 0.04 1.78 0 5.00
15 INT304016 SFRP4 Regulation of Binding of MSI1 1 0.04 1.78 0 5.00
16 INT304013 Binding of SUZ12 and JAZF1 1 0.30 1.89 0 5.00
17 INT304024 Binding of AKT1 and PTEN 1 0.33 1.08 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Papilloma. They are ordered first by their pain relevance and then by number of times they were reported in Papilloma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT237256 Positive_regulation of Rhbdl1 6 0.47 4.64 0.78 100.00
2 INT237257 Gene_expression of Rhbdl1 3 0.67 5.15 4.31 100.00
3 INT237259 Positive_regulation of Gene_expression of Rhbdl1 1 0.50 3.58 0 100.00
4 INT237258 Binding of Rhbdl1 2 0.37 1.27 0.28 100.00
5 INT237255 Regulation of Rhbdl1 2 0.27 0.63 0.39 100.00
6 INT7293 Negative_regulation of Binding of Nppa 5 0.43 1.4 0.55 99.52
7 INT6210 Binding of Nppa 39 0.47 14.35 7.21 99.52
8 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 99.28
9 INT51921 Gene_expression of Cpox 501 0.73 229.81 157.81 99.00
10 INT70130 Positive_regulation of Casp8ap2 3 0.42 0.97 0.2 98.40
11 INT85340 Positive_regulation of Slc22a13 1 0.04 0.95 0.11 97.68
12 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 95.76
13 INT22708 Gene_expression of MUC1 297 0.78 232.71 24.19 95.24
14 INT5623 Positive_regulation of Nppa 174 0.70 69.96 52.33 93.92
15 INT67190 Gene_expression of Muc2 24 0.78 18.8 2.08 91.44
16 INT45840 Positive_regulation of Gene_expression of Ptgs1 35 0.50 16.07 20.49 78.04
17 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58 76.12
18 INT14701 Negative_regulation of IFNA1 118 0.54 84.19 20.08 75.92
19 INT67191 Gene_expression of Muc3 11 0.29 9.93 0.91 71.16
20 INT46777 Localization of FECD7 1 0.61 2.09 0.16 59.92
21 INT172996 Gene_expression of MUC2 14 0.69 11.01 0.42 27.28
22 INT156595 Gene_expression of CDX2 10 0.69 7.8 0.25 27.28
23 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 22.88
24 INT146546 Gene_expression of MSI1 22 0.48 22.91 1.15 21.20
25 INT107987 Gene_expression of MRC1 27 0.75 36.94 1.99 20.80
26 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54 20.72
27 INT257455 Binding of PDLIM5 2 0.08 1.72 0.64 19.16
28 INT24042 Gene_expression of MUC5AC 98 0.77 74.99 6.18 18.32
29 INT173023 Gene_expression of MUC6 13 0.69 9.77 0.46 18.32
30 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
31 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
32 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
33 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
34 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
35 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
36 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
37 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 5.00
38 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
39 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31 5.00
40 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38 5.00
41 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
42 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
43 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 5.00
44 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 5.00
45 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 5.00
46 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 5.00
47 INT9292 Positive_regulation of SGCG 93 0.67 35.13 23.48 5.00
48 INT11157 Binding of EGF 88 0.48 53.73 21.25 5.00
49 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94 5.00
50 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61 5.00
51 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 5.00
52 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9 5.00
53 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 5.00
54 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 5.00
55 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51 5.00
56 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 5.00
57 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 5.00
58 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59 5.00
59 INT20420 Gene_expression of MYC 99 0.75 49.32 14.36 5.00
60 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99 5.00
61 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 5.00
62 INT53747 Positive_regulation of Cyp2e1 34 0.70 29.03 13.39 5.00
63 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 5.00
64 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 5.00
65 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32 5.00
66 INT48335 Negative_regulation of NOSTRIN 38 0.56 16.22 12.05 5.00
67 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64 5.00
68 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 5.00
69 INT22132 Positive_regulation of CAT 41 0.67 18.64 10.67 5.00
70 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 5.00
71 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57 5.00
72 INT91370 Phosphorylation of STAT3 123 0.82 49.25 8.42 5.00
73 INT108202 Positive_regulation of PIK3CG 47 0.67 25.83 8.25 5.00
74 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 5.00
75 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49 5.00
76 INT75501 Gene_expression of CCND1 90 0.76 60.86 5.93 5.00
77 INT38671 Positive_regulation of KRT20 62 0.53 40.17 5.6 5.00
78 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23 5.00
79 INT60585 Regulation of TP53 59 0.59 54.55 5.21 5.00
80 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07 5.00
81 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 5.00
82 INT105336 Regulation of AKT1 52 0.56 32.53 4.89 5.00
83 INT10115 Gene_expression of INSR 31 0.75 11.98 4.86 5.00
84 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62 5.00
85 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45 5.00
86 INT109450 Positive_regulation of Phosphorylation of AKT1 62 0.64 25.18 4.21 5.00
87 INT84686 Regulation of BAX 26 0.49 28.54 4.13 5.00
88 INT111477 Gene_expression of KRT7 90 0.74 86.76 4.07 5.00
89 INT101857 Negative_regulation of BCL2L1 22 0.57 23.56 3.95 5.00
90 INT97126 Regulation of CASP3 9 0.40 8.15 3.6 5.00
91 INT64766 Gene_expression of TWIST1 41 0.76 37.89 3.4 5.00
92 INT51607 Positive_regulation of DES 33 0.67 32.24 3.29 5.00
93 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21 5.00
94 INT192676 Binding of PTEN 14 0.46 10.58 3.06 5.00
95 INT89392 Negative_regulation of Positive_regulation of AKT1 23 0.50 15.69 3.02 5.00
96 INT200670 Gene_expression of AKT2 25 0.75 16.25 3 5.00
97 INT11775 Gene_expression of Ema 39 0.65 38.12 2.99 5.00
98 INT89397 Positive_regulation of PIK3CA 33 0.67 16.98 2.78 5.00
99 INT74293 Positive_regulation of BAK1 13 0.60 14.13 2.73 5.00
100 INT90875 Negative_regulation of CCND1 31 0.42 26.22 2.66 5.00
101 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5 5.00
102 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48 5.00
103 INT147582 Negative_regulation of AIS 13 0.37 13.26 2.46 5.00
104 INT72782 Positive_regulation of HCC 41 0.40 63.74 2.46 5.00
105 INT25208 Gene_expression of IGF2 43 0.74 30.64 2.31 5.00
106 INT94002 Regulation of Lox 13 0.38 8.41 2.29 5.00
107 INT179885 Regulation of PTEN 8 0.26 11.88 2.18 5.00
108 INT38674 Regulation of KRT20 32 0.44 19 2.15 5.00
109 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98 5.00
110 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97 5.00
111 INT20421 Positive_regulation of MYC 19 0.67 10.43 1.9 5.00
112 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87 5.00
113 INT48792 Regulation of ERBB2 48 0.57 36.56 1.8 5.00
114 INT86909 Negative_regulation of MSH2 9 0.41 12.65 1.7 5.00
115 INT94169 Negative_regulation of Phosphorylation of RB1 16 0.41 8.87 1.57 5.00
116 INT65684 Gene_expression of MDM2 30 0.62 24.94 1.55 5.00
117 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41 5.00
118 INT304045 Transcription of PTEN 2 0.51 4.12 1.4 5.00
119 INT201463 Negative_regulation of CCNE2 7 0.39 3.31 1.36 5.00
120 INT92383 Gene_expression of KRAS 38 0.65 32.94 1.32 5.00
121 INT137382 Negative_regulation of Gene_expression of KRT20 22 0.58 12.29 1.29 5.00
122 INT139237 Negative_regulation of Gene_expression of CDH1 23 0.57 24.31 1.28 5.00
123 INT210399 Gene_expression of IGF2R 22 0.65 17.1 1.23 5.00
124 INT10117 Positive_regulation of INSR 10 0.43 4.71 1.22 5.00
125 INT119832 Positive_regulation of Gene_expression of PTEN 12 0.49 7.12 1.19 5.00
126 INT135556 Localization of AKT1 38 0.69 12.78 1.17 5.00
127 INT220206 Gene_expression of CCNB2 4 0.67 3.75 1.16 5.00
128 INT111605 Positive_regulation of CDH1 12 0.50 7.95 1.15 5.00
129 INT157765 Negative_regulation of CDH1 32 0.53 35.72 1.15 5.00
130 INT86908 Negative_regulation of MLH1 7 0.43 6.98 1.12 5.00
131 INT92139 Binding of MLH1 12 0.42 15.62 1 5.00
132 INT294726 Positive_regulation of Lts1 5 0.49 4.06 0.87 5.00
133 INT163280 Negative_regulation of Phosphorylation of CCND1 6 0.19 3.92 0.87 5.00
134 INT163289 Phosphorylation of CCND1 7 0.36 4.81 0.81 5.00
135 INT275575 Gene_expression of FOLR1 12 0.66 2.81 0.8 5.00
136 INT108204 Regulation of PIK3CG 9 0.12 4.16 0.75 5.00
137 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75 5.00
138 INT86370 Regulation of CDH1 10 0.54 13.89 0.7 5.00
139 INT2395 Binding of MB 18 0.36 7.53 0.68 5.00
140 INT206139 Phosphorylation of KRT20 8 0.48 9.1 0.66 5.00
141 INT304060 Positive_regulation of AGR2 2 0.70 13 0.63 5.00
142 INT47038 Gene_expression of SFRP1 14 0.67 9.6 0.63 5.00
143 INT44478 Negative_regulation of PTEN 32 0.57 27.45 0.63 5.00
144 INT161322 Localization of PTEN 9 0.73 5.65 0.57 5.00
145 INT88870 Negative_regulation of PDXP 4 0.43 4.64 0.57 5.00
146 INT201846 Positive_regulation of SFRP4 4 0.37 2.74 0.54 5.00
147 INT201858 Gene_expression of SFRP4 3 0.48 4.91 0.51 5.00
148 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47 5.00
149 INT47030 Negative_regulation of ARMC9 22 0.38 13.08 0.47 5.00
150 INT148882 Regulation of LTF 9 0.12 4.8 0.44 5.00
151 INT12089 Positive_regulation of MSX2 4 0.46 3.92 0.39 5.00
152 INT81644 Regulation of Ctnnb1 5 0.41 3.38 0.37 5.00
153 INT185886 Gene_expression of JUP 20 0.75 15.41 0.32 5.00
154 INT107983 Gene_expression of MSH6 6 0.51 5.57 0.27 5.00
155 INT113989 Regulation of Gene_expression of CCND1 11 0.44 7.57 0.24 5.00
156 INT181920 Gene_expression of MSH3 2 0.50 2.54 0.18 5.00
157 INT242278 Localization of SIVA1 1 0.01 1.07 0.17 5.00
158 INT242277 Positive_regulation of SIVA1 1 0.01 1.08 0.17 5.00
159 INT206869 Gene_expression of ALDH1A2 3 0.38 2.51 0.16 5.00
160 INT292659 Positive_regulation of Gene_expression of FOLR1 2 0.47 1.59 0.14 5.00
161 INT200671 Gene_expression of AKT3 4 0.69 1.88 0.13 5.00
162 INT165516 Regulation of MSX2 8 0.23 3.41 0.09 5.00
163 INT184985 Regulation of TFF3 2 0.26 1.43 0.07 5.00
164 INT182302 Negative_regulation of Localization of AKT1 5 0.39 3.52 0.06 5.00
165 INT206866 Positive_regulation of SFRP1 7 0.51 3.97 0.05 5.00
166 INT105948 Gene_expression of AURKA 5 0.65 4.26 0.03 5.00
167 INT207233 Transcription of KRAS 3 0.48 1.56 0.03 5.00
168 INT176154 Gene_expression of PIK3CA 6 0.55 10.43 0.03 5.00
169 INT105949 Positive_regulation of Gene_expression of AURKA 3 0.49 1.91 0.03 5.00
170 INT219360 Regulation of MMP11 2 0.54 1.71 0.03 5.00
171 INT172329 Binding of MRC1 8 0.36 3.88 0.03 5.00
172 INT282953 Regulation of MSI1 2 0.03 1.63 0.03 5.00
173 INT304047 Positive_regulation of Transcription of TWIST1 1 0.10 0.57 0 5.00
174 INT304067 Positive_regulation of Transcription of GEMIN2 1 0.09 0.57 0 5.00
175 INT304078 Regulation of Phosphorylation of KRT20 1 0.00 1 0 5.00
176 INT304046 Positive_regulation of Transcription of SNAI2 1 0.49 0.57 0 5.00
177 INT304062 Regulation of Localization of PTEN 1 0.43 1.29 0 5.00
178 INT304074 Binding of MSH5 1 0.14 1.11 0 5.00
179 INT236621 Regulation of KRAS 7 0.53 6.16 0 5.00
180 INT304066 Gene_expression of BUB1 1 0.07 1.41 0 5.00
181 INT304063 Positive_regulation of ALDH1A2 1 0.29 0.97 0 5.00
182 INT304075 Regulation of AURKA 1 0.15 1.38 0 5.00
183 INT304059 Gene_expression of GEMIN2 1 0.12 0.66 0 5.00
184 INT304058 Positive_regulation of MSI1 1 0.07 2.74 0 5.00
185 INT198037 Regulation of PIK3CA 2 0.28 2.63 0 5.00
186 INT291934 Regulation of FOXA2 2 0.26 2.15 0 5.00
187 INT304050 Gene_expression of SUZ12 1 0.54 6.53 0 5.00
188 INT190053 Gene_expression of CASP5 3 0.45 2.46 0 5.00
189 INT304076 Regulation of Localization of KRAS 2 0.36 2.39 0 5.00
190 INT304049 Transcription of SNAI2 1 0.67 0.56 0 5.00
191 INT304052 Binding of MSI1 8 0.05 12.19 0 5.00
192 INT268686 Gene_expression of JAZF1 2 0.68 9.33 0 5.00
193 INT304051 Regulation of SCGB2A1 1 0.17 1.19 0 5.00
194 INT304065 Transcription of GEMIN2 1 0.12 0.57 0 5.00
195 INT180396 Localization of KRAS 3 0.69 2.89 0 5.00
196 INT341719 Transcription of FAM49B 1 0.04 1.1 0 5.00
197 INT304053 Gene_expression of KIAA1324 1 0.18 0.98 0 5.00
198 INT304064 Positive_regulation of KIAA1324 1 0.14 0.98 0 5.00
199 INT185004 Positive_regulation of TFF3 4 0.47 3.77 0 5.00
200 INT304073 Regulation of CCNB2 1 0.10 1.39 0 5.00
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