D:Paratuberculosis

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Disease Johne, Disease Johne S, JOHNE DISEASE, Johne S Disease, Johnes Disease, Paratuberculoses
Documents 19
Hot Single Events 39
Hot Interactions 4

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Paratuberculosis. They are ordered first by their relevance to Paratuberculosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT260578 Binding of IGHG3 and SGSM3 1 0.00 1.07 0 100.00
2 INT260577 Binding of ALPP and SGSM3 1 0.00 1.06 0 100.00
3 INT238007 Binding of Cxcr3 and Saa 1 0.14 0.95 0.11 96.64
4 INT238008 Myd88 Regulation of Hand1 1 0.03 0.82 0.04 94.96
5 INT238003 Aif1 Regulation of IgG 1 0.00 0.21 0.03 79.52
6 INT238005 Binding of Cxcr3 and Cxcl10 2 0.38 3.73 1.42 78.44
7 INT238009 Binding of Cxcr3 and Cxcl9 3 0.40 4.01 1.37 78.44
8 INT237999 Binding of Cxcr3 and Cxcl11 2 0.45 3.49 1.11 78.44
9 INT238004 Positive_regulation of Binding of Cxcr3 and Cxcl11 1 0.30 1.86 0.51 78.44
10 INT238001 Cxcl10 Positive_regulation of Gene_expression of Cd40 1 0.17 0.91 0.21 5.00
11 INT238000 Cxcl10 Positive_regulation of Cd4 1 0.21 0.91 0.21 5.00
12 INT238006 Cxcl10 Positive_regulation of Gene_expression of Cd28 1 0.24 0.91 0.21 5.00
13 INT238002 Cxcl10 Positive_regulation of Positive_regulation of Cd4 1 0.21 0.91 0.21 5.00
14 INT238010 Binding of Cxcr3 and Hand1 1 0.12 1.55 0.19 5.00
15 INT288006 Binding of CD28 and LRRC23 1 0.02 0.54 0.19 5.00
16 INT288007 Binding of CD28 and CD40 1 0.05 0.51 0.03 5.00
17 INT288008 Binding of CD40 and LRRC23 1 0.02 0.45 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Paratuberculosis. They are ordered first by their pain relevance and then by number of times they were reported in Paratuberculosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT38859 Gene_expression of SGSM3 14 0.75 12.98 4.09 100.00
2 INT2683 Binding of SGSM3 6 0.36 7.98 1.2 100.00
3 INT85233 Localization of SGSM3 11 0.78 10.91 3.41 100.00
4 INT260582 Transcription of SGSM3 1 0.05 1.55 0.03 100.00
5 INT46833 Positive_regulation of SGSM3 56 0.67 24.49 30.31 100.00
6 INT38858 Positive_regulation of Gene_expression of SGSM3 5 0.49 4.15 3.05 100.00
7 INT75530 Regulation of SGSM3 11 0.60 7.22 4.48 100.00
8 INT67551 Gene_expression of Mbis1 6 0.35 3.32 0.17 100.00
9 INT79358 Gene_expression of ERVW-1 65 0.75 29.9 1.31 99.64
10 INT143998 Binding of IK 11 0.34 2.44 3.42 98.84
11 INT9223 Localization of Ighg1 22 0.78 11.03 3.67 98.62
12 INT224714 Localization of Ighg2b 4 0.73 0.48 0.33 98.62
13 INT129483 Localization of Arigg4 3 0.50 1.66 0.19 98.62
14 INT237989 Localization of Ighg3 1 0.11 0.15 0.03 98.62
15 INT260581 Binding of DMPK 7 0.43 5.09 0.28 97.80
16 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 97.40
17 INT27919 Positive_regulation of Mbis1 6 0.02 2.28 0.9 97.04
18 INT168410 Gene_expression of Cxcr3 81 0.75 84.03 37.01 96.60
19 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 96.60
20 INT177759 Negative_regulation of IFN1@ 51 0.57 31.81 7.76 94.48
21 INT142754 Binding of Myd88 20 0.36 9.61 3.8 92.72
22 INT17934 Localization of MLN 16 0.80 2.83 2.24 92.24
23 INT28576 Binding of MLN 18 0.48 5.45 2.26 91.76
24 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 89.24
25 INT80667 Gene_expression of PFKM 4 0.57 2.13 0.07 88.72
26 INT6852 Localization of TNF 883 0.81 705.95 270.84 88.56
27 INT260583 Binding of PFKM 1 0.02 1.22 0.03 87.92
28 INT219247 Positive_regulation of Ddx41 9 0.36 6.7 0.84 86.68
29 INT139679 Positive_regulation of Ighg2b 11 0.55 10.57 1.1 86.68
30 INT68244 Positive_regulation of Ighg1 60 0.61 48.86 5.01 86.68
31 INT237991 Positive_regulation of Aif1 4 0.04 4.87 0.77 86.68
32 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 84.68
33 INT72747 Localization of IgG 55 0.53 30.88 4.19 83.92
34 INT215120 Negative_regulation of Localization of IgG 5 0.16 3.44 0.43 83.92
35 INT82955 Localization of Ddx41 4 0.53 1.08 0.06 83.92
36 INT237994 Negative_regulation of Localization of Ddx41 1 0.04 0.08 0 83.92
37 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 83.20
38 INT129231 Gene_expression of Ddx41 29 0.63 9.73 1.52 83.04
39 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53 80.40
40 INT22389 Regulation of MLN 9 0.61 4.39 3.08 79.52
41 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 79.52
42 INT131359 Positive_regulation of Gene_expression of Cd4 40 0.58 22.43 7.53 79.52
43 INT161599 Binding of Saa 11 0.41 8.61 2.34 76.80
44 INT163960 Localization of Saa 4 0.49 4.28 1.75 76.80
45 INT104392 Gene_expression of Cxcl10 113 0.75 106.86 34.12 75.24
46 INT104395 Gene_expression of Cxcl9 83 0.76 73.1 19.79 75.24
47 INT237051 Gene_expression of Cxcl11 24 0.64 25.74 5.77 75.24
48 INT104394 Positive_regulation of Gene_expression of Cxcl10 28 0.65 25.64 8.79 75.24
49 INT174427 Positive_regulation of Gene_expression of Cxcr3 8 0.66 10.7 4.66 75.24
50 INT104389 Positive_regulation of Gene_expression of Cxcl9 15 0.49 17.42 4.59 75.24
51 INT237047 Positive_regulation of Gene_expression of Cxcl11 5 0.43 5.04 1.17 75.24
52 INT101301 Gene_expression of Aif1 17 0.42 16.43 4.06 72.56
53 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 71.68
54 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43 69.72
55 INT188588 Localization of Mthfd1 20 0.49 9.19 4.37 67.92
56 INT174422 Binding of Cxcr3 24 0.47 26.09 8.34 67.00
57 INT73252 Positive_regulation of Mthfd1 124 0.59 59.48 18.35 65.68
58 INT21900 Gene_expression of Mthfd1 150 0.75 69.47 27.03 63.84
59 INT58449 Binding of Mthfd1 47 0.47 22.02 10.29 63.60
60 INT174439 Regulation of Gene_expression of Cxcr3 2 0.43 3.24 1.17 62.84
61 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 58.88
62 INT137177 Positive_regulation of CXCL11 6 0.67 4.17 1.13 58.48
63 INT220165 Positive_regulation of Cxcl11 8 0.60 9.67 2.29 57.92
64 INT142752 Positive_regulation of Myd88 26 0.66 12.07 4.4 56.56
65 INT104045 Regulation of Hand1 65 0.35 51.32 16.26 53.68
66 INT133172 Gene_expression of Il12b 98 0.75 52.16 10.68 52.40
67 INT99784 Positive_regulation of Cxcr3 22 0.66 22.44 10.36 50.76
68 INT22388 Gene_expression of MLN 15 0.75 4.86 1.14 50.00
69 INT94463 Regulation of Gene_expression of Hand1 10 0.36 5.17 2.72 42.68
70 INT237990 Regulation of Gene_expression of Cxcl9 2 0.44 1.91 0.58 42.68
71 INT237992 Regulation of Gene_expression of Cxcl11 1 0.33 0.81 0.05 42.68
72 INT145888 Negative_regulation of Mthfd1 27 0.41 8.98 5.4 40.04
73 INT20378 Localization of Hand1 53 0.71 41.96 13.31 38.96
74 INT187819 Regulation of IFN1@ 25 0.60 12.89 3.55 38.96
75 INT170754 Localization of IFN1@ 121 0.78 66.78 15.6 38.80
76 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49 38.32
77 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 34.32
78 INT53196 Binding of Cd4 44 0.47 27.28 5.85 33.44
79 INT170333 Binding of IFN1@ 68 0.47 49.01 9.72 32.44
80 INT138913 Negative_regulation of Gene_expression of Cxcl9 8 0.58 6.22 1.36 29.52
81 INT238012 Positive_regulation of Gene_expression of MLN 1 0.04 1.51 0.17 29.08
82 INT188590 Positive_regulation of Gene_expression of Mthfd1 23 0.49 16.56 2.84 28.64
83 INT20371 Gene_expression of Cd8a 125 0.60 67.59 8.97 27.76
84 INT178175 Positive_regulation of Gene_expression of Cd8a 17 0.43 13.05 0.78 27.76
85 INT44136 Positive_regulation of MLN 8 0.69 1.77 1.42 21.24
86 INT237986 Regulation of Gene_expression of Cd8a 3 0.24 0.83 0.1 14.76
87 INT238011 Regulation of Gene_expression of MLN 1 0.04 0.7 0.03 14.76
88 INT77677 Positive_regulation of Saa 30 0.49 33.19 11.18 14.48
89 INT99778 Localization of Cxcl10 12 0.75 14.24 3.91 12.96
90 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
91 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
92 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 5.00
93 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
94 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 5.00
95 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 5.00
96 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 5.00
97 INT96156 Gene_expression of Cd40 144 0.77 56.95 21.7 5.00
98 INT192409 Positive_regulation of Gene_expression of IFN1@ 102 0.67 64.66 18.8 5.00
99 INT10000 Regulation of Gene_expression of IL2 56 0.45 15.33 16.2 5.00
100 INT11699 Binding of HLA-E 85 0.47 52.51 13.41 5.00
101 INT10870 Regulation of IgG 67 0.59 43.27 12.74 5.00
102 INT95565 Positive_regulation of IL12A 47 0.56 33.96 10.16 5.00
103 INT61628 Negative_regulation of Gene_expression of IL4 31 0.55 20.96 8.18 5.00
104 INT94125 Gene_expression of Cd28 38 0.67 21.73 7.75 5.00
105 INT1952 Negative_regulation of Positive_regulation of Tlr4 33 0.51 15.8 7.41 5.00
106 INT103909 Gene_expression of NOD2 37 0.77 21.9 7.36 5.00
107 INT1950 Positive_regulation of Positive_regulation of Tlr4 38 0.49 20.17 7.14 5.00
108 INT116229 Gene_expression of C1qa 28 0.77 18.53 5.35 5.00
109 INT98251 Binding of IL12A 20 0.37 16.03 4.51 5.00
110 INT124655 Negative_regulation of PECAM1 13 0.23 10.32 3.78 5.00
111 INT93913 Positive_regulation of CD40 21 0.58 23.47 3.1 5.00
112 INT103910 Binding of NOD2 19 0.47 12.24 2.93 5.00
113 INT133174 Positive_regulation of Gene_expression of Il12b 29 0.15 13.04 2.92 5.00
114 INT163063 Positive_regulation of C1qa 10 0.67 6.06 2.29 5.00
115 INT163064 Positive_regulation of Gene_expression of C1qa 9 0.67 6.51 2.29 5.00
116 INT250888 Negative_regulation of IL23A 4 0.30 6.13 2.15 5.00
117 INT46162 Regulation of C6orf25 12 0.39 5.42 1.61 5.00
118 INT204772 Negative_regulation of Gene_expression of Mthfd1 10 0.15 3.48 1.29 5.00
119 INT277920 Binding of MADCAM1 4 0.14 3.11 0.96 5.00
120 INT221508 Phosphorylation of IFN1@ 14 0.79 8.97 0.77 5.00
121 INT160941 Negative_regulation of LASP1 2 0.29 1.57 0.59 5.00
122 INT237987 Negative_regulation of Gene_expression of Cxcl11 2 0.42 2.38 0.48 5.00
123 INT250482 Transcription of CMBL 1 0.01 1.19 0.23 5.00
124 INT288015 Regulation of SLC44A4 1 0.10 0.59 0.19 5.00
125 INT288013 Binding of EIF3H 1 0.01 0.94 0.18 5.00
126 INT250481 Gene_expression of CMBL 1 0.01 0.87 0.16 5.00
127 INT131376 Positive_regulation of REL 2 0.45 1.02 0.15 5.00
128 INT197707 Gene_expression of SLC39A8 1 0.22 0.28 0.1 5.00
129 INT288011 Negative_regulation of Positive_regulation of REL 1 0.08 0.63 0.09 5.00
130 INT288014 Negative_regulation of Positive_regulation of CD40 1 0.17 0.63 0.09 5.00
131 INT238013 Negative_regulation of Gene_expression of MLN 2 0.42 0.64 0.08 5.00
132 INT237988 Negative_regulation of Phosphorylation of Cxcr3 1 0.32 0.65 0.07 5.00
133 INT238014 Negative_regulation of Phosphorylation of IFN1@ 2 0.41 1.27 0.07 5.00
134 INT237993 Phosphorylation of Cxcr3 1 0.61 0.65 0.07 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox