D:Parkinson's Disease

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pChart

Disease Term
Synonyms "1 Methyl 4 Phenyl 1,2,3,6 Tetrahydropyridine", Alpha Synuclein Aggregation, ALZHEIMER S PARKINSON S, Idiopathic Parkinson Disease, Idiopathic Parkinson S Disease, Lewy Bodies, Lewy Body Parkinson Disease, Lewy Body Parkinson S Disease, Mitochondrial Dysfunction, Mitochondrial Inhibition, MITOCHONDRIAL INHIBITORS
Documents 1510
Hot Single Events 200
Hot Interactions 180

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Parkinson's Disease. They are ordered first by their relevance to Parkinson's Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT349504 Ptpn2 Negative_regulation of Th 1 0.23 2 0.19 100.00
2 INT106893 Ptpn2 Positive_regulation of Tac1 1 0.02 2.02 0.29 100.00
3 INT268627 Ptpn2 Positive_regulation of Gsk3b 1 0.02 1.7 0.08 100.00
4 INT277432 Ptpn2 Positive_regulation of Gdnf 1 0.29 1.41 0.06 100.00
5 INT336573 Ptpn2 Regulation of INSR 1 0.00 1.36 0.36 100.00
6 INT23755 Mptp1 Regulation of PDYN 1 0.01 2.27 1.98 100.00
7 INT349511 Ptpn2 Positive_regulation of Ptpn2 Negative_regulation of Th 1 0.16 1.3 0.03 100.00
8 INT296869 Mtor Positive_regulation of Gene_expression of B4galnt2 1 0.01 1.56 0 100.00
9 INT349483 Cyp7b1 Negative_regulation of Ptpn2 Negative_regulation of Th 1 0.25 0.76 0.16 100.00
10 INT221232 Ptpn2 Positive_regulation of Gene_expression of Ros1 1 0.04 1.12 0.07 100.00
11 INT349505 Ptpn2 Negative_regulation of Slc6a3 1 0.19 0.7 0.16 100.00
12 INT349503 Ptpn2 Negative_regulation of Gene_expression of Th 1 0.23 0.7 0.16 100.00
13 INT106894 Ptpn2 Negative_regulation of Tac1 1 0.02 1.17 0.1 100.00
14 INT277435 Ptpn2 Positive_regulation of Ptpn2 Positive_regulation of Gdnf 1 0.20 0.94 0.05 100.00
15 INT37153 Binding of Mpz and Ptpn2 1 0.12 0.68 1.08 100.00
16 INT64735 Mptp1 Positive_regulation of Mpz 1 0.22 0.59 0.14 100.00
17 INT296868 Binding of B4galnt2 and Map1lc3a 1 0.04 0.69 0.03 100.00
18 INT221247 Hspa9 Negative_regulation of Ptpn2 1 0.03 0.67 0 100.00
19 INT268634 Ptpn2 Positive_regulation of Positive_regulation of Gsk3b 1 0.02 1.08 0.11 100.00
20 INT277427 Ptpn2 Positive_regulation of Gene_expression of Gdnf 1 0.32 0.47 0.03 100.00
21 INT277429 Ptpn2 Regulation of Gdnf 1 0.34 0.47 0.03 100.00
22 INT277428 Positive_regulation of Ptpn2 Positive_regulation of Gdnf 1 0.29 0.47 0.03 100.00
23 INT311557 Binding of ROS1 and Ptpn2 1 0.02 2.32 0.46 100.00
24 INT221251 PRKG1 Negative_regulation of Positive_regulation of Ptpn2 1 0.04 0.7 0.05 100.00
25 INT112596 Tgfb1 Negative_regulation of Negative_regulation of Mptp1 1 0.26 0.72 0.22 100.00
26 INT112595 Tgfb1 Negative_regulation of Gene_expression of Mptp1 1 0.27 0.72 0.22 100.00
27 INT221246 Prkca Negative_regulation of Ptpn2 1 0.04 0.54 0.6 100.00
28 INT210225 Ptpn2 Positive_regulation of Gene_expression of Ifng 1 0.15 1.44 0.42 100.00
29 INT296867 Binding of B4galnt2 and Mtor 1 0.00 0.51 0 100.00
30 INT64639 Slc1a1 Positive_regulation of Ddc 1 0.30 0.3 0.38 100.00
31 INT221234 Gja3 Regulation of Binding of Ptpn2 1 0.08 0.58 0.18 100.00
32 INT261579 Serpinc1 Negative_regulation of Gene_expression of CYBB 1 0.00 1.69 0.18 100.00
33 INT268630 Mpz Positive_regulation of Regulation of Gsk3b 1 0.18 0.57 0.07 100.00
34 INT268626 Mpz Positive_regulation of Positive_regulation of Gsk3b 1 0.29 1.08 0.11 99.98
35 INT149095 PITX2 Positive_regulation of Casp3 1 0.00 1.51 0.15 99.92
36 INT149092 PITX2 Positive_regulation of RFFL 1 0.00 1.51 0.15 99.92
37 INT261391 Binding of Nsdhl and P4hb 1 0.02 1.3 0.1 99.90
38 INT320398 Binding of Psmb10 and Psmf1 1 0.00 0.1 0 99.88
39 INT340743 Negative_regulation of CSF2 Positive_regulation of ZNF807 1 0.00 1.77 0 99.84
40 INT346913 Binding of Kars and Positive_regulation of Gene_expression of Ros1 1 0.03 1.25 0.46 99.72
41 INT354823 IFNA1 Positive_regulation of Racgap1 1 0.00 1.4 0.15 99.64
42 INT99797 Jun Positive_regulation of Creb1 1 0.15 0.19 0.2 99.26
43 INT331227 Binding of Becn1 and Pink1 1 0.03 1.13 0.05 99.24
44 INT313452 Phosphorylation of Siglec1 Regulation of Syp 1 0.06 0.1 0 99.22
45 INT60719 Insrr Positive_regulation of Fos 1 0.03 1.23 0.84 99.20
46 INT340745 CSF2 Positive_regulation of ZNF807 1 0.00 1.76 0 99.12
47 INT58678 Binding of Penk and Abat 2 0.40 1.39 1.97 99.10
48 INT221256 Negative_regulation of CYC1 Positive_regulation of Gene_expression of Ros1 1 0.07 0.96 0 98.72
49 INT346914 Binding of Kars and Positive_regulation of Gene_expression of Car2 1 0.05 1.24 0.45 98.44
50 INT342181 Binding of Igfals and Ros1 1 0.01 0.76 0.41 98.40
51 INT277433 Wibg Positive_regulation of Gdnf 1 0.01 0.6 0.13 98.40
52 INT277430 Wibg Positive_regulation of Gene_expression of Gdnf 1 0.01 0.6 0.13 98.40
53 INT113146 Ddc Positive_regulation of Gene_expression of Nr4a1 1 0.06 0.1 0.63 98.36
54 INT221242 Ros1 Positive_regulation of Prkca 1 0.02 0.39 1.44 98.32
55 INT221236 Ros1 Positive_regulation of Localization of Prkca 1 0.01 0.15 0.27 98.32
56 INT221253 PRKG1 Negative_regulation of Ros1 1 0.01 0.69 0.05 98.28
57 INT334718 Binding of NOS1 and Bax 1 0.02 0.87 0 98.20
58 INT225785 Enpp3 Regulation of Ppi-rs 1 0.00 0.69 0.11 98.16
59 INT185851 BID Positive_regulation of BAK1 1 0.43 0.73 0 98.12
60 INT185854 BID Positive_regulation of BAD 1 0.39 0.74 0 98.12
61 INT185850 BID Positive_regulation of BAX 1 0.41 0.73 0 98.12
62 INT336556 SLC6A3 Positive_regulation of Gene_expression of GOPC 1 0.08 1.87 1.76 97.28
63 INT313456 Binding of Ppp2ca and Gopc 1 0.08 0.68 0 97.24
64 INT317314 Gfm1 Positive_regulation of Gene_expression of Ros1 1 0.00 0.61 0 97.08
65 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26 97.04
66 INT327972 Negative_regulation of BCL2 Positive_regulation of BAX 1 0.22 0.82 0 97.04
67 INT342726 Binding of Laptm5 and Park2 1 0.03 0.64 0.04 96.92
68 INT327977 TNFRSF11A Regulation of BCL2 1 0.05 0.67 0 96.92
69 INT261380 Nsdhl Negative_regulation of P4hb 1 0.02 1.36 0.11 96.90
70 INT281881 Binding of Aco1 and Ros1 1 0.01 1.93 0.1 96.40
71 INT313426 Positive_regulation of Ppp2ca Positive_regulation of Bax 1 0.46 0.36 0 96.32
72 INT184922 Negative_regulation of Th Negative_regulation of da 1 0.12 0.18 0.52 96.12
73 INT215281 Mpz Positive_regulation of Gene_expression of Ros1 2 0.01 1.01 0.05 96.00
74 INT190524 Ros1 Positive_regulation of Nfkb1 3 0.02 4.24 2.06 95.96
75 INT175986 Ros1 Positive_regulation of Gtf3a 2 0.01 4.75 1.71 95.96
76 INT147179 Esr1 Regulation of Gene_expression of Penk 1 0.01 0.68 0.46 95.28
77 INT255660 Coq10a Negative_regulation of Rgc32 1 0.02 1.11 0.13 95.24
78 INT72513 LOC100044193 Regulation of Regulation of Penk 1 0.00 0.56 0.17 95.00
79 INT310241 INS Positive_regulation of Akt1 1 0.30 0.98 0 94.96
80 INT310240 INS Positive_regulation of Trib3 1 0.00 0.98 0 94.96
81 INT317321 Mpz Positive_regulation of Gene_expression of Zfp263 1 0.02 0.58 0 94.92
82 INT336559 SLC6A3 Positive_regulation of GOPC 1 0.08 1 1.15 94.56
83 INT336557 SLC6A3 Positive_regulation of Binding of GOPC 1 0.08 0.5 0.58 94.56
84 INT349506 S100a8 Positive_regulation of Gene_expression of Nos2 1 0.02 0.67 0.28 94.24
85 INT221243 Binding of Hspa9 and Ppif 1 0.01 0.67 0.03 94.12
86 INT260727 Binding of Gfm1 and NAFLD2 1 0.00 1.05 0 94.08
87 INT260726 Positive_regulation of Binding of Gfm1 and NAFLD2 1 0.00 1.05 0 94.08
88 INT93740 Ddc Positive_regulation of Tnf 1 0.00 1.45 0.5 93.96
89 INT334737 Binding of Oprd1 and Gpi 1 0.01 0.71 0.28 93.92
90 INT221249 Hspa9 Negative_regulation of Gene_expression of Ros1 1 0.01 0.91 0 93.84
91 INT221241 Sf3a2 Negative_regulation of Gene_expression of Ros1 1 0.00 0.91 0 93.84
92 INT215644 Binding of Drd2 and Adora2a 1 0.03 0.23 0.55 93.76
93 INT201770 Binding of CASP9 and Apaf1 1 0.04 0.89 0.03 93.72
94 INT275756 xn Regulation of Ins1 1 0.01 3.25 0 93.64
95 INT313435 Syp Regulation of Th 1 0.43 1.6 0.64 93.52
96 INT255658 Coq10a Regulation of Negative_regulation of Rgc32 1 0.01 1.14 0.14 93.52
97 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01 93.36
98 INT335042 Binding of CNBP and ANAPC16 1 0.01 0.4 0 93.32
99 INT204995 Ppp1r15b Regulation of Gene_expression of Pink1 1 0.01 0.97 0 93.00
100 INT262825 Serpinf1 Negative_regulation of Gfap 1 0.34 0.87 0.08 92.80
101 INT298688 Binding of OPA1 and MFN1 1 0.52 2.09 0 92.64
102 INT298687 Binding of OPA1 and PARL 1 0.50 2.09 0 92.64
103 INT74727 Binding of Slc6a4 and Hpic1 1 0.00 0.49 0.68 92.52
104 INT333511 STON1 Positive_regulation of GYPE 1 0.10 0.49 0.12 92.32
105 INT333509 STON1 Positive_regulation of GPI 1 0.04 0.49 0.12 92.32
106 INT317317 Binding of Psmb10 and Gfm1 1 0.00 0.73 0 92.12
107 INT295921 Mir761 Positive_regulation of Gene_expression of Ndufv2 1 0.00 0.64 0 92.12
108 INT295919 Mir761 Regulation of Gene_expression of Ndufv2 1 0.00 0.64 0 92.12
109 INT215284 Siglec1 Negative_regulation of Binding of Mpz 1 0.01 0.63 0.08 92.00
110 INT342731 Pink1 Regulation of Localization of Gfm1 1 0.00 0.61 0 92.00
111 INT225783 Enpp1 Regulation of Ppi-rs 1 0.07 0.68 0.13 92.00
112 INT313446 Syp Regulation of Ppp2ca 1 0.58 0.62 0.26 91.92
113 INT215286 Siglec1 Negative_regulation of Gene_expression of Ros1 1 0.00 2.76 0.25 91.56
114 INT207265 ZNF236 Positive_regulation of Gene_expression of TXNIP 1 0.04 1.6 0 91.56
115 INT215277 Siglec1 Negative_regulation of Gene_expression of Mpz 1 0.02 0.48 0.03 91.56
116 INT215285 Siglec1 Negative_regulation of Positive_regulation of Ros1 1 0.00 0.48 0.03 91.56
117 INT74728 Binding of Slc6a4 and Ptprj 1 0.01 0.48 0.68 91.24
118 INT262821 Serpinf1 Negative_regulation of Gene_expression of Il18 1 0.54 0.85 0.08 90.88
119 INT313459 Gene_expression of Syp Negative_regulation of Th 1 0.30 0.49 0.08 90.76
120 INT262826 Serpinf1 Negative_regulation of Gene_expression of TNF 1 0.29 1.83 0.28 90.08
121 INT204994 Positive_regulation of Hras1 Positive_regulation of Gene_expression of Pink1 1 0.05 0.97 0 89.84
122 INT273046 Vip Negative_regulation of Gene_expression of Adcyap1 1 0.20 1.14 0.21 89.76
123 INT332538 Binding of AD5 and Cxadr 1 0.08 0.98 0.76 89.72
124 INT207263 ZNF236 Positive_regulation of Gene_expression of ROS1 1 0.01 0.67 0 89.20
125 INT60718 Negative_regulation of Insrr Positive_regulation of Fos 1 0.01 0.6 0.42 89.12
126 INT345209 Repin1 Positive_regulation of Positive_regulation of Trib3 1 0.00 0.88 0.18 88.92
127 INT157097 Ddc Positive_regulation of Drd3 1 0.30 0.88 0.16 88.60
128 INT184919 Binding of da and Slc6a3 1 0.12 0.33 1.23 88.52
129 INT342725 Pink1 Positive_regulation of Phosphorylation of Park2 1 0.29 0.62 0 88.16
130 INT342727 Pink1 Positive_regulation of Park2 1 0.29 0.62 0 88.16
131 INT184916 Binding of da and Th 1 0.09 1.22 0.87 88.12
132 INT336561 Binding of DDC and DIO2 1 0.04 0.27 0.24 88.04
133 INT349608 Binding of DIO2 and LMOD1 1 0.23 0.41 2.01 88.00
134 INT317320 Binding of Snca and Atp13a2 1 0.08 0.58 0 87.88
135 INT261390 Binding of Nsdhl and Bdnf 1 0.05 1.33 0.12 87.16
136 INT262822 Serpinf1 Negative_regulation of Negative_regulation of 1190002H23Rik 1 0.07 1.27 0.18 86.72
137 INT313453 Siglec1 Regulation of Th 1 0.02 0.61 0.17 86.36
138 INT313449 Siglec1 Regulation of Ppp2ca 1 0.03 0.61 0.17 86.36
139 INT342733 Gene_expression of Lrrk2 Positive_regulation of Apaf1 1 0.10 0.74 0.03 86.32
140 INT161004 Binding of Cpe and Cpb2 1 0.03 0.53 0.37 86.08
141 INT161011 Binding of Cpe and St13 2 0.03 0.61 1.07 86.08
142 INT161009 Binding of Cpe and Itgam 1 0.03 0.53 0.37 86.08
143 INT161000 Binding of Cpe and Gfap 1 0.05 0.53 0.37 86.08
144 INT87605 Binding of FOS and Penk 1 0.07 0.78 0.4 85.96
145 INT87603 Binding of FOS and Jund 1 0.03 0.77 0.39 85.96
146 INT340742 Positive_regulation of CSF2 Regulation of BDNF 1 0.22 1.46 0.14 85.84
147 INT317313 Atp13a2 Negative_regulation of Snca 1 0.13 0.59 0 85.52
148 INT317315 Gene_expression of Snca Negative_regulation of Psmb10 1 0.00 0.52 0 85.52
149 INT340744 CSF2 Regulation of BDNF 1 0.13 1.45 0.14 85.48
150 INT306677 Binding of Mapt and Atxn3 1 0.07 0.49 0 85.40
151 INT313443 Syp Positive_regulation of Binding of Th 1 0.35 0.31 0 85.28
152 INT315543 NARFL Regulation of Gene_expression of HIF1A 1 0.01 0.63 0 85.24
153 INT114077 Gtf3a Positive_regulation of Tfam 1 0.09 1.08 0.09 85.04
154 INT178438 Mapk8 Positive_regulation of Plau 1 0.06 0.52 0.06 85.04
155 INT340399 Binding of Bak1 and Bax 1 0.12 0.91 0 84.56
156 INT317310 Binding of Large and Psmb10 1 0.00 0.94 0.03 84.12
157 INT313431 Positive_regulation of Binding of Ppp2ca and Gopc 1 0.11 0.34 0 83.76
158 INT161006 Itgam Regulation of Cpb2 1 0.07 0.52 0.37 83.64
159 INT161003 Binding of Itgam and Cpb2 1 0.10 0.52 0.37 83.64
160 INT161002 Binding of Itgam and St13 1 0.11 0.52 0.37 83.64
161 INT161008 Itgam Regulation of St13 1 0.08 0.52 0.37 83.64
162 INT161001 Itgam Regulation of Gfap 1 0.13 0.52 0.37 83.64
163 INT185852 Binding of BAK1 and BAX 3 0.29 2.5 0 83.36
164 INT301667 Tlr4 Positive_regulation of Gene_expression of CYBB 1 0.01 0.84 0.03 83.28
165 INT301662 Binding of Tlr4 and Positive_regulation of Gene_expression of CYBB 1 0.01 0.84 0.03 83.28
166 INT161007 Gfap Regulation of Cpb2 1 0.04 0.52 0.37 83.24
167 INT160999 Binding of Gfap and Cpb2 1 0.14 0.52 0.37 83.24
168 INT161005 Binding of Gfap and St13 1 0.15 0.52 0.37 83.24
169 INT161010 Gfap Regulation of St13 1 0.05 0.52 0.37 83.24
170 INT87604 FOS Regulation of Penk 1 0.09 0.76 0.39 83.00
171 INT322931 Binding of MOCS1 and Litaf 1 0.00 0.82 0 83.00
172 INT310230 INS Negative_regulation of Localization of SUCLA2 1 0.07 1.09 0 82.92
173 INT313455 Binding of Ppp2ca and Syp 1 0.45 0.68 0.4 82.84
174 INT313428 Binding of Syp and Th 1 0.25 0.31 0 82.84
175 INT320399 Binding of Vcp and Psmb10 1 0.00 0.16 0 81.44
176 INT313465 Syp Regulation of Regulation of Ppp2ca 1 0.26 0.56 0 81.04
177 INT149096 PITX2 Positive_regulation of Gene_expression of Egr1 1 0.01 1.23 0.19 80.92
178 INT215283 Tlr4 Positive_regulation of Localization of Ncf1 2 0.05 1.04 0.11 80.56
179 INT268629 Mpz Regulation of Phosphorylation of Gsk3b 1 0.26 1.05 0.03 80.20
180 INT332539 Regulation of Binding of AD5 and Cxadr 1 0.09 0.65 0.44 80.20
181 INT342737 Pink1 Positive_regulation of HTRA2 1 0.29 0.58 0 79.84
182 INT342736 Pink1 Positive_regulation of Phosphorylation of HTRA2 1 0.29 0.58 0 79.84
183 INT313429 Syp Regulation of Phosphorylation of Siglec1 1 0.04 0.57 0 78.44
184 INT323186 TFAM Positive_regulation of HIST1H1B 1 0.01 0.49 0 78.16
185 INT221254 Binding of KNG1 and Akt1 1 0.00 0.13 0.13 77.16
186 INT190751 Adcyap1 Positive_regulation of Vipr2 2 0.16 1.02 0.36 76.52
187 INT169218 Binding of EGFR and Coc 1 0.06 2.8 5.85 76.48
188 INT327981 CASP9 Positive_regulation of CASP3 2 0.29 1.34 0 76.00
189 INT207251 TXNIP Positive_regulation of ZNF236 1 0.03 0.84 0 75.80
190 INT273048 Adcyap1 Positive_regulation of Adcyap1r1 1 0.11 1.02 0.19 75.72
191 INT207260 INS Negative_regulation of Gene_expression of TXNIP 1 0.39 1.71 0 75.04
192 INT352519 INS Positive_regulation of Localization of Slc2a4 1 0.07 0.97 0.03 75.04
193 INT140289 ROS1 Positive_regulation of MAPK14 1 0.44 1.27 0.06 75.00
194 INT140291 ROS1 Positive_regulation of TP53 1 0.52 1.27 0.06 75.00
195 INT181449 Ccl7 Regulation of Ccl2 1 0.24 0.73 0.25 74.96
196 INT313466 Syp Negative_regulation of Siglec1 1 0.05 0.24 0.12 74.96
197 INT268631 Mpz Regulation of Akt1 1 0.12 0.48 0 74.88
198 INT261629 Binding of CPD and TRPC5 1 0.04 0.52 0.32 74.88
199 INT268628 Mpz Positive_regulation of Phosphorylation of Gsk3b 1 0.25 0.43 0 74.64
200 INT193454 Dbh Negative_regulation of Negative_regulation of Ndufaf1 1 0.02 1.22 0.05 74.48

Single Events

The table below shows the top 200 pain related interactions that have been reported for Parkinson's Disease. They are ordered first by their pain relevance and then by number of times they were reported in Parkinson's Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT43901 Negative_regulation of Ptpn2 65 0.37 56.32 7.48 100.00
2 INT161107 Gene_expression of Ptpn2 58 0.58 49.92 7.4 100.00
3 INT90823 Positive_regulation of Ptpn2 25 0.59 22.97 3.59 100.00
4 INT43903 Regulation of Ptpn2 21 0.41 15.51 4.08 100.00
5 INT154007 Gene_expression of da 46 0.56 15.28 28.22 100.00
6 INT15310 Gene_expression of DLEU1 8 0.67 20.57 0.96 100.00
7 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 100.00
8 INT39060 Gene_expression of Mpz 45 0.77 21.55 4.3 100.00
9 INT221210 Negative_regulation of Gene_expression of Ptpn2 9 0.37 8.3 0.84 100.00
10 INT221190 Phosphorylation of Ptpn2 9 0.48 7 1.15 100.00
11 INT296857 Gene_expression of B4galnt2 1 0.07 9.46 0.55 100.00
12 INT340751 Binding of DLEU1 1 0.20 12.05 0.49 100.00
13 INT56292 Negative_regulation of Gene_expression of Ros1 70 0.38 36.14 9.17 100.00
14 INT11769 Regulation of Mptp1 8 0.60 6.38 2.68 100.00
15 INT133876 Positive_regulation of Gene_expression of Ros1 141 0.32 75.55 27.45 100.00
16 INT5648 Negative_regulation of Mptp1 7 0.37 6.64 3.08 100.00
17 INT334212 Negative_regulation of DLEU1 2 0.28 8.84 0.53 100.00
18 INT221207 Localization of Ptpn2 5 0.74 5.76 0.59 100.00
19 INT797 Regulation of Penk 812 0.62 111.13 542.24 100.00
20 INT64734 Positive_regulation of Mpz 17 0.67 6.81 2.55 100.00
21 INT5647 Positive_regulation of Mptp1 5 0.30 3.6 2.01 100.00
22 INT14301 Binding of CSF2 82 0.48 67.95 8.98 100.00
23 INT268616 Positive_regulation of Gene_expression of Ptpn2 7 0.43 8.14 2.08 100.00
24 INT204987 Binding of Pink1 3 0.37 4.72 0.17 100.00
25 INT204971 Gene_expression of Pink1 42 0.77 23.95 4.75 100.00
26 INT43902 Binding of Ptpn2 6 0.29 3.59 0.93 100.00
27 INT296845 Regulation of B4galnt2 1 0.05 4.76 0.08 100.00
28 INT221218 Regulation of Negative_regulation of Ptpn2 3 0.30 2.69 0.79 100.00
29 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 100.00
30 INT161743 Negative_regulation of Gene_expression of Mptp1 1 0.25 2.83 0.89 100.00
31 INT315626 Localization of DLEU1 2 0.35 4.17 0.07 100.00
32 INT36355 Gene_expression of Mptp1 3 0.39 3.01 0.88 100.00
33 INT68890 Binding of Mptp1 2 0.14 1.81 0 100.00
34 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76 100.00
35 INT204975 Positive_regulation of Pink1 7 0.69 5.17 0.14 100.00
36 INT37152 Localization of Mpz 7 0.68 2.64 2.95 100.00
37 INT112689 Protein_catabolism of Ptpn2 1 0.59 1.45 0.44 100.00
38 INT159121 Positive_regulation of Map3k1 10 0.45 8.79 2.6 100.00
39 INT28510 Positive_regulation of Gpi 21 0.68 6.75 14.27 100.00
40 INT112003 Localization of ROS1 94 0.73 66.32 12.16 100.00
41 INT204983 Positive_regulation of Gene_expression of Pink1 1 0.50 2.03 0.16 100.00
42 INT264073 Positive_regulation of Negative_regulation of Ptpn2 1 0.13 0.86 0.32 100.00
43 INT204969 Negative_regulation of Pink1 1 0.58 7.03 0.75 100.00
44 INT19393 Gene_expression of Gfm1 31 0.51 18.9 3.2 100.00
45 INT25451 Negative_regulation of Gfm1 13 0.27 8.22 1.06 100.00
46 INT204986 Gene_expression of Park7 5 0.38 5.48 0.1 100.00
47 INT15990 Binding of Gfm1 10 0.31 8.53 1.37 100.00
48 INT23542 Negative_regulation of B4galnt2 3 0.22 1.67 0.6 100.00
49 INT349490 Positive_regulation of Positive_regulation of Ptpn2 1 0.39 2.33 0.8 100.00
50 INT221205 Regulation of Phosphorylation of Ptpn2 1 0.26 0.93 0.14 100.00
51 INT257932 Negative_regulation of Positive_regulation of H2 2 0.18 1.02 0.08 100.00
52 INT176517 Negative_regulation of Gene_expression of Spp1 18 0.59 15.31 2.28 100.00
53 INT23541 Positive_regulation of B4galnt2 3 0.26 0.92 0.62 100.00
54 INT296848 Positive_regulation of Regulation of B4galnt2 1 0.05 0.92 0.08 100.00
55 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 100.00
56 INT1488 Negative_regulation of Negative_regulation of Cpe 3 0.42 0.86 2.42 100.00
57 INT24142 Regulation of DLEU1 1 0.21 1.01 0.85 100.00
58 INT50266 Regulation of Negative_regulation of Th 1 0.42 0.94 0.88 100.00
59 INT349489 Negative_regulation of Positive_regulation of Ptpn2 1 0.33 0.81 0.17 100.00
60 INT296865 Regulation of Gene_expression of B4galnt2 1 0.05 0.77 0.03 100.00
61 INT204990 Positive_regulation of Gene_expression of Park7 2 0.24 1.79 0.05 100.00
62 INT340754 Negative_regulation of Negative_regulation of CSF2 1 0.31 1.25 0 100.00
63 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16 100.00
64 INT5594 Regulation of Pdyn 137 0.62 27.04 86.63 100.00
65 INT63133 Gene_expression of Pd 13 0.18 5.31 0.61 100.00
66 INT101450 Positive_regulation of DLEU1 2 0.22 2.65 0.12 100.00
67 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03 100.00
68 INT338445 Positive_regulation of parkinsonism 1 0.01 3.26 0.47 100.00
69 INT202475 Positive_regulation of Positive_regulation of Map3k1 2 0.33 1.54 0 100.00
70 INT50785 Gene_expression of Map3k1 6 0.44 4.22 1.32 100.00
71 INT50784 Positive_regulation of Gene_expression of Map3k1 2 0.06 0.94 0.8 100.00
72 INT204973 Positive_regulation of Park7 2 0.23 1.62 0.03 100.00
73 INT20064 Regulation of Gene_expression of Cpe 9 0.47 2.05 5.16 100.00
74 INT20065 Regulation of Negative_regulation of Mptp1 1 0.17 0.53 0.96 100.00
75 INT221208 Negative_regulation of Negative_regulation of Ptpn2 1 0.25 0.76 0.04 100.00
76 INT36356 Positive_regulation of Gene_expression of Mptp1 1 0.10 0.89 0.22 100.00
77 INT136791 Negative_regulation of Spp1 24 0.59 23.6 3.33 100.00
78 INT221223 Phosphorylation of VDAC1 1 0.01 1.16 0.63 100.00
79 INT296866 Positive_regulation of Localization of B4galnt2 1 0.05 0.94 0 100.00
80 INT11266 Positive_regulation of UMOD 2 0.43 1.25 1.16 100.00
81 INT296847 Localization of B4galnt2 1 0.08 0.93 0 100.00
82 INT107341 Phosphorylation of MAPT 19 0.80 14 1.61 100.00
83 INT85843 Negative_regulation of BPI 5 0.35 5.13 3.77 100.00
84 INT77249 Positive_regulation of Gene_expression of gr 24 0.67 16.09 8.17 100.00
85 INT131165 Positive_regulation of Gene_expression of Nr3c1 8 0.70 7.18 3.44 100.00
86 INT340750 Phosphorylation of DLEU1 1 0.44 1.28 0 100.00
87 INT300682 Phosphorylation of Cyb5r3 1 0.07 0.37 0.08 100.00
88 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4 100.00
89 INT338444 Binding of parkinsonism 1 0.00 1.43 0.25 100.00
90 INT349488 Positive_regulation of Localization of Th 1 0.30 0.96 0.34 100.00
91 INT281868 Negative_regulation of Park7 1 0.00 1.69 0.14 100.00
92 INT137637 Negative_regulation of Localization of Endog 1 0.41 0.39 0.39 100.00
93 INT137640 Negative_regulation of Localization of Aifm1 2 0.58 0.39 0.39 100.00
94 INT296859 Negative_regulation of Gene_expression of B4galnt2 1 0.05 0.38 0.1 100.00
95 INT354815 Transcription of Ptpn2 1 0.29 0.61 0.27 100.00
96 INT209336 Gene_expression of Filipino 5 0.10 4.75 1.2 100.00
97 INT334210 Negative_regulation of Negative_regulation of DLEU1 1 0.09 1.14 0 100.00
98 INT145654 Negative_regulation of Sod2 4 0.59 2.81 1.33 100.00
99 INT6824 Regulation of Gene_expression of Pdyn 114 0.62 9.48 66.73 100.00
100 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24 100.00
101 INT87139 Negative_regulation of Positive_regulation of Il6 18 0.59 10.65 7.76 100.00
102 INT123130 Positive_regulation of Positive_regulation of AKT1 22 0.49 11.77 1.83 100.00
103 INT163592 Localization of CISH 5 0.54 5.9 1.26 100.00
104 INT26063 Regulation of SH3BP5 2 0.45 1.99 0.92 100.00
105 INT160124 Localization of Mptp1 1 0.10 0.36 0.13 100.00
106 INT24240 Positive_regulation of Th 60 0.70 9.92 20.18 99.98
107 INT208536 Positive_regulation of Positive_regulation of Gsk3b 6 0.30 4.83 1.11 99.98
108 INT108548 Positive_regulation of Dntt 3 0.49 3.26 1.19 99.98
109 INT15173 Positive_regulation of Gene_expression of Itgam 59 0.49 21.89 5.43 99.98
110 INT90640 Positive_regulation of Negative_regulation of Th 2 0.40 0.58 0.39 99.98
111 INT317275 Positive_regulation of Binding of Snca 1 0.37 0.53 0 99.98
112 INT221213 Negative_regulation of Hspa9 7 0.34 2.79 1.18 99.98
113 INT349498 Negative_regulation of Cyp7b1 1 0.41 2.61 0.36 99.96
114 INT112692 Localization of Bax 31 0.80 20.97 3.98 99.96
115 INT15171 Positive_regulation of Positive_regulation of Itgam 4 0.49 1.13 0.64 99.96
116 INT69439 Regulation of ROS1 46 0.45 31.22 6.94 99.96
117 INT47691 Positive_regulation of Gene_expression of Ntrk2 17 0.62 13.64 6.96 99.96
118 INT4683 Negative_regulation of PDXK 17 0.55 12.81 4.39 99.96
119 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 99.92
120 INT40034 Localization of Maoa 7 0.80 2.17 3.69 99.92
121 INT282619 Localization of Maob 1 0.40 1.67 0.18 99.92
122 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 99.92
123 INT5069 Negative_regulation of Mthfs 69 0.57 22.54 31.36 99.92
124 INT25128 Gene_expression of Mthfs 9 0.25 2.38 2.75 99.92
125 INT25132 Negative_regulation of Gene_expression of Mthfs 2 0.08 0.39 0.33 99.92
126 INT123593 Gene_expression of Snca 58 0.78 35.76 12.87 99.90
127 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 99.90
128 INT334716 Negative_regulation of NDUFV1 1 0.01 1.59 0.23 99.90
129 INT102747 Gene_expression of Hmbs 17 0.78 10.53 1.34 99.90
130 INT146785 Positive_regulation of Localization of Bax 7 0.69 6.16 1.47 99.88
131 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97 99.88
132 INT320421 Binding of Psmf1 1 0.01 0.1 0 99.88
133 INT36293 Gene_expression of Mtor 24 0.25 14.5 2.04 99.86
134 INT161248 Positive_regulation of Gene_expression of Mtor 2 0.06 6.47 0.51 99.86
135 INT163613 Transcription of CSF2 16 0.60 12.98 1.62 99.86
136 INT64248 Positive_regulation of Positive_regulation of Drd1a 6 0.45 1.97 2.62 99.86
137 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 99.84
138 INT26408 Negative_regulation of da 36 0.18 13.46 20.32 99.84
139 INT2289 Gene_expression of PENK 203 0.78 55.62 79.49 99.84
140 INT296844 Gene_expression of Atg7 1 0.62 10.64 0.86 99.84
141 INT67039 Positive_regulation of Cpox 144 0.65 98.4 33.77 99.84
142 INT160853 Gene_expression of Syp 87 0.72 20.06 5.31 99.84
143 INT127125 Localization of Snca 6 0.81 8.24 1.88 99.84
144 INT258135 Gene_expression of CARTPT 3 0.40 5.25 1.88 99.84
145 INT254881 Negative_regulation of Atg7 9 0.34 5.69 0.32 99.84
146 INT296852 Negative_regulation of Gene_expression of Atg7 1 0.47 4.67 0.19 99.84
147 INT245670 Positive_regulation of Gene_expression of Syp 37 0.65 7.34 1.25 99.84
148 INT4742 Gene_expression of Tac1 177 0.78 69.99 102.66 99.84
149 INT1635 Gene_expression of Vip 245 0.78 53.36 88.13 99.84
150 INT60032 Negative_regulation of Pla2g2a 29 0.58 12.42 5.75 99.84
151 INT21214 Negative_regulation of Gene_expression of PENK 21 0.58 9.14 9.53 99.84
152 INT20944 Gene_expression of Mcf2l 13 0.58 5.96 4.76 99.84
153 INT51206 Regulation of Gene_expression of Tac1 13 0.45 5.92 7.74 99.84
154 INT267875 Phosphorylation of St13 6 0.12 1.69 1.55 99.84
155 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 99.84
156 INT133231 Regulation of PYCARD 18 0.39 5.02 4.44 99.84
157 INT114 Binding of Oprl1 139 0.48 23 103.35 99.84
158 INT12734 Regulation of Binding of Oprl1 10 0.62 2.23 7.71 99.84
159 INT14318 Negative_regulation of MAPT 3 0.57 2.05 0.59 99.84
160 INT7894 Negative_regulation of Vip 59 0.59 11.76 27.36 99.84
161 INT6174 Regulation of Gene_expression of POMC 49 0.61 9.75 27.69 99.84
162 INT204170 Binding of Mri1 5 0.22 4.45 1.11 99.84
163 INT19768 Negative_regulation of LAMC2 11 0.57 10.54 5.32 99.84
164 INT219 Negative_regulation of Th 55 0.59 20.88 17.09 99.82
165 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 99.82
166 INT184914 Negative_regulation of Gene_expression of Th 15 0.43 9.17 2.46 99.82
167 INT81037 Negative_regulation of Slc6a3 70 0.59 15.31 37.01 99.82
168 INT245663 Phosphorylation of Syp 2 0.76 7.4 1.88 99.82
169 INT12359 Negative_regulation of Tac1 26 0.58 8.16 6.89 99.82
170 INT15174 Gene_expression of Itgam 238 0.73 104.92 29.26 99.82
171 INT1486 Negative_regulation of Cpe 85 0.59 28.78 54.08 99.82
172 INT55470 Regulation of Mtor 16 0.24 12.51 2.07 99.82
173 INT184845 Negative_regulation of Gene_expression of Slc6a3 13 0.59 3.25 7.79 99.82
174 INT50267 Negative_regulation of Negative_regulation of Th 3 0.42 1.57 1.12 99.82
175 INT212458 Binding of Mtor 8 0.04 6.77 0.03 99.82
176 INT109266 Negative_regulation of Transcription of Th 9 0.42 2.5 6.85 99.82
177 INT97869 Negative_regulation of Positive_regulation of Th 3 0.25 0.79 1.23 99.82
178 INT349491 Negative_regulation of Transcription of Slc6a3 1 0.22 0.7 0.16 99.82
179 INT282729 Regulation of Binding of Mtor 2 0.05 1.48 0.03 99.82
180 INT261366 Binding of P4hb 1 0.04 1.3 0.1 99.82
181 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.80
182 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 99.80
183 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 99.80
184 INT13382 Negative_regulation of Maob 13 0.57 11.73 2.72 99.80
185 INT303796 Gene_expression of Tdp1 1 0.77 70.15 2.55 99.80
186 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 99.80
187 INT94784 Binding of ROS1 113 0.40 71.57 10.26 99.80
188 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 99.80
189 INT163405 Positive_regulation of Binding of ROS1 15 0.27 9.39 2.58 99.80
190 INT135372 Positive_regulation of Gsk3b 72 0.70 50.03 9.28 99.78
191 INT7056 Positive_regulation of Gene_expression of PENK 35 0.70 14.31 18.21 99.78
192 INT1429 Gene_expression of PDYN 308 0.78 61.33 175.65 99.78
193 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1 99.78
194 INT218 Positive_regulation of Th 245 0.70 40.5 120.1 99.78
195 INT156945 Positive_regulation of Negative_regulation of Gsk3b 6 0.38 4.58 0.82 99.78
196 INT91159 Negative_regulation of Ros1 35 0.44 26.12 5.97 99.78
197 INT49439 Gene_expression of Cpox 508 0.73 326.97 130.17 99.76
198 INT7692 Positive_regulation of PENK 71 0.70 20.34 32.54 99.76
199 INT131296 Positive_regulation of Bace1 208 0.70 170.1 15.79 99.76
200 INT124860 Gene_expression of Bace1 330 0.78 157.11 31.65 99.76
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