D:Paronychia

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pChart

Disease Term
Synonyms PARONYCHIAS
Documents 55
Hot Single Events 4
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Paronychia. They are ordered first by their relevance to Paronychia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT134454 EGF Positive_regulation of EGFR 3 0.56 1.32 0.88 5.00
2 INT274060 EGF Positive_regulation of EGFR Positive_regulation of TKT 1 0.08 1 0 5.00
3 INT327101 Binding of AREG and EGF 1 0.05 0.35 0 5.00
4 INT274061 EGF Positive_regulation of EGFR Positive_regulation of TXK 1 0.06 1 0 5.00
5 INT327100 Binding of BTC and EGF 1 0.04 0.35 0 5.00
6 INT327099 Binding of EGF and EREG 1 0.05 0.35 0 5.00
7 INT274062 EGF Positive_regulation of EGFR Positive_regulation of Positive_regulation of TXK 1 0.06 1 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Paronychia. They are ordered first by their pain relevance and then by number of times they were reported in Paronychia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT320644 Binding of Egfr 7 0.34 5.9 0.56 99.98
2 INT119506 Negative_regulation of Egfr 32 0.55 23.75 3.67 99.66
3 INT76177 Binding of YOD1 2 0.15 1.29 0.21 99.64
4 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 96.76
5 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 70.68
6 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 64.96
7 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 50.64
8 INT114246 Positive_regulation of Negative_regulation of EGFR 13 0.49 8.67 0.7 49.28
9 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 45.28
10 INT11154 Binding of EGFR 149 0.48 96.23 6.29 21.36
11 INT96994 Phosphorylation of EGFR 99 0.82 52.75 7.33 18.88
12 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
13 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74 5.00
14 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47 5.00
15 INT11157 Binding of EGF 88 0.48 53.73 21.25 5.00
16 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 5.00
17 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59 5.00
18 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55 5.00
19 INT701 Localization of IGHE 87 0.80 40.5 10.62 5.00
20 INT39712 Binding of pad 82 0.48 110.92 10.33 5.00
21 INT2036 Localization of EGF 42 0.77 21.5 9.74 5.00
22 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68 5.00
23 INT113705 Gene_expression of Egfr 228 0.78 149.05 7.59 5.00
24 INT2037 Negative_regulation of EGF 30 0.59 15.05 6.81 5.00
25 INT5847 Transcription of FOS 31 0.69 11.11 6.41 5.00
26 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 5.00
27 INT93684 Gene_expression of STAT3 66 0.78 34.42 5.94 5.00
28 INT82611 Negative_regulation of SRC 30 0.57 20.16 5.47 5.00
29 INT14778 Gene_expression of FCGR3A 25 0.75 16.25 3.86 5.00
30 INT120715 Positive_regulation of Egfr 15 0.68 5.53 3.77 5.00
31 INT121818 Binding of STAT3 25 0.47 11.16 3.67 5.00
32 INT18920 Binding of Egf 24 0.48 9.43 3.57 5.00
33 INT118035 Positive_regulation of JAK1 23 0.67 10.57 3.29 5.00
34 INT124954 Gene_expression of Egfr 26 0.75 15.08 3.12 5.00
35 INT117348 Regulation of EGFR 75 0.61 47.73 3.09 5.00
36 INT89397 Positive_regulation of PIK3CA 33 0.67 16.98 2.78 5.00
37 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5 5.00
38 INT118791 Binding of AKT1 32 0.48 15.51 2.25 5.00
39 INT82226 Negative_regulation of Gene_expression of EGF 11 0.58 6.36 2.13 5.00
40 INT65545 Localization of EGFR 35 0.79 20.8 1.88 5.00
41 INT35368 Positive_regulation of Tk1 9 0.53 4.68 1.81 5.00
42 INT119520 Gene_expression of TXK 19 0.19 17.54 1.45 5.00
43 INT131457 Gene_expression of FCGR1A 11 0.75 4.88 1.45 5.00
44 INT41719 Gene_expression of MTOR 27 0.77 19.43 1.44 5.00
45 INT47950 Negative_regulation of ELOVL1 15 0.41 20.33 1.41 5.00
46 INT49128 Gene_expression of IGF1R 35 0.63 23.48 1.39 5.00
47 INT92383 Gene_expression of KRAS 38 0.65 32.94 1.32 5.00
48 INT125525 Positive_regulation of PRKDC 7 0.45 2.72 1.21 5.00
49 INT60060 Positive_regulation of KRAS 17 0.67 11.68 1.21 5.00
50 INT51264 Positive_regulation of TXK 21 0.54 10.69 1.1 5.00
51 INT11160 Regulation of Gene_expression of EGFR 27 0.62 22.05 0.96 5.00
52 INT306856 Transcription of CDC25A 2 0.28 0.85 0.92 5.00
53 INT144416 Regulation of Egfr 5 0.57 4.97 0.83 5.00
54 INT306854 Positive_regulation of CDC25A 3 0.37 1.57 0.82 5.00
55 INT51262 Positive_regulation of TKT 7 0.69 4.31 0.82 5.00
56 INT119834 Phosphorylation of PTEN 12 0.79 6.78 0.75 5.00
57 INT92382 Positive_regulation of Gene_expression of KRAS 7 0.49 4.82 0.71 5.00
58 INT213923 Positive_regulation of MTOR 16 0.65 9.28 0.7 5.00
59 INT44478 Negative_regulation of PTEN 32 0.57 27.45 0.63 5.00
60 INT153610 Positive_regulation of SPN 3 0.49 3.04 0.44 5.00
61 INT98708 Binding of KRAS 13 0.47 7.47 0.39 5.00
62 INT186057 Binding of CCND1 8 0.31 5.92 0.26 5.00
63 INT223597 Negative_regulation of Binding of EGFR 12 0.43 7.97 0.23 5.00
64 INT192958 Negative_regulation of IGF1R 8 0.30 6.35 0.21 5.00
65 INT276344 Positive_regulation of PIM1 3 0.25 1.07 0.17 5.00
66 INT233419 Negative_regulation of Positive_regulation of Egfr 2 0.40 0.97 0.12 5.00
67 INT249280 Phosphorylation of PRKDC 2 0.13 0.3 0.07 5.00
68 INT205021 Positive_regulation of Gene_expression of Egfr 3 0.64 4.15 0.05 5.00
69 INT207233 Transcription of KRAS 3 0.48 1.56 0.03 5.00
70 INT315886 Regulation of Positive_regulation of PIK3CA 1 0.10 0.53 0 5.00
71 INT293769 Positive_regulation of CCND3 3 0.06 0.23 0 5.00
72 INT327105 Transcription of CCND3 1 0.04 0.28 0 5.00
73 INT236621 Regulation of KRAS 7 0.53 6.16 0 5.00
74 INT327104 Transcription of PIM1 1 0.13 0.29 0 5.00
75 INT315883 Positive_regulation of Positive_regulation of JAK1 1 0.01 0.38 0 5.00
76 INT315882 Regulation of Negative_regulation of PTEN 2 0.44 1.39 0 5.00
77 INT206695 Gene_expression of GFM1 3 0.58 0.77 0 5.00
78 INT258234 Regulation of EMR1 2 0.01 0.22 0 5.00
79 INT315881 Binding of Eltd1 1 0.01 0.61 0 5.00
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