D:Pathologic Constriction

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Disease Term
Synonyms Constriction Pathological, Constrictions Pathologic, Pathologic Constrictions, Pathological Constriction, Stenoses, Stenosis
Documents 7439
Hot Single Events 200
Hot Interactions 15

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Pathologic Constriction. They are ordered first by their relevance to Pathologic Constriction and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT180200 Binding of BCAR1 and MMVP1 1 0.11 8.57 0.08 100.00
2 INT323926 MRM1 Positive_regulation of MRI1 1 0.04 0.44 0.26 98.72
3 INT133745 Vcan Regulation of TNC 1 0.11 0.71 0.46 96.84
4 INT150532 LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12 95.48
5 INT150533 Positive_regulation of LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12 95.48
6 INT106744 Binding of CRP and EGFL7 2 0.07 2.35 0.51 95.04
7 INT353836 Binding of CEACAM7 and ICA1 1 0.08 0.32 0.39 93.16
8 INT344717 Binding of Niacr1 and Hdl1 1 0.17 1.51 0 91.96
9 INT302384 IL6 Positive_regulation of Localization of Crp 1 0.10 1.39 0.15 91.80
10 INT333150 Tlx2 Regulation of asa 1 0.04 2.17 1.55 87.12
11 INT244349 Binding of GSTM1 and GSTK1 1 0.35 1.22 0 86.88
12 INT117971 Cd8a Negative_regulation of Positive_regulation of Ephb1 1 0.02 0.98 0.79 85.96
13 INT299955 Binding of KDR and FTSJ3 1 0.04 1.07 0.09 85.40
14 INT299953 Binding of CD34 and FTSJ3 1 0.04 1.07 0.09 85.40
15 INT129874 Binding of CST3 and CTSS 1 0.42 2.45 0 82.96
16 INT131853 CD40 Negative_regulation of Gene_expression of CD40LG 1 0.09 1.54 1.05 77.28
17 INT310674 Positive_regulation of Binding of ARSB and ELF3 1 0.07 2.46 0.05 73.60
18 INT310675 Binding of ARSB and ELF3 1 0.06 2.4 0.05 73.04
19 INT258018 Binding of AGT and RASGRP1 1 0.00 1.59 0.1 70.28
20 INT212770 Binding of CTD and TGFB1 1 0.01 3.95 0 69.76
21 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19 69.64
22 INT258014 Binding of ANGPT2 and RASGRP1 1 0.00 1.58 0.1 69.64
23 INT265828 ACE Regulation of Gene_expression of KNG1 1 0.32 0.83 0.22 69.48
24 INT115006 Binding of Serpine1 and Cpb2 1 0.09 1.53 0.2 67.36
25 INT196592 Binding of CFD and GHRH 1 0.02 1.88 0.07 63.56
26 INT302385 Il1b Positive_regulation of Nfib Positive_regulation of Gene_expression of Ccl2 1 0.00 1.48 0.09 63.36
27 INT302380 Tnf Positive_regulation of Nfib 1 0.00 1.41 0.09 63.36
28 INT302383 Il1b Positive_regulation of Nfib 1 0.00 1.42 0.09 63.36
29 INT154755 Tnf Positive_regulation of Gene_expression of Ccl2 2 0.23 1.7 0.27 59.84
30 INT302382 Il1b Positive_regulation of Gene_expression of Ccl2 1 0.00 1.39 0.09 58.72
31 INT326303 Binding of CRP and FKBP4 1 0.15 1.22 0.41 51.60
32 INT192309 Binding of GSTM1 and GSTT1 2 0.43 4.54 0.06 46.64
33 INT145886 Binding of CXCL1 and Adipoq 1 0.00 0.77 0.2 43.04
34 INT262996 ADIPOQ Regulation of INS 1 0.13 1.25 0.1 40.32
35 INT239839 IL18 Positive_regulation of TNF 1 0.11 1.08 0.09 36.24
36 INT270777 Binding of DMD and BPs 1 0.01 0.33 0.09 24.72
37 INT177714 Binding of GALNT3 and REN 1 0.01 2.36 0.12 19.32
38 INT269783 Crp Positive_regulation of Sele 1 0.00 1.69 0.11 15.84
39 INT269785 Crp Positive_regulation of ICAM1 1 0.00 1.68 0.11 14.56
40 INT181619 ACE Positive_regulation of KNG1 1 0.33 0.97 0.58 13.88
41 INT265827 ACE Negative_regulation of ANGPT2 1 0.09 0.59 0.17 13.88
42 INT269784 Crp Positive_regulation of Vcam1 1 0.00 1.6 0.11 11.76
43 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48 5.00
44 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 5.00
45 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69 5.00
46 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68 5.00
47 INT208991 Binding of CALM1 and Ca2 10 0.06 1.34 1.55 5.00
48 INT181490 Tryptase Positive_regulation of F2rl1 1 0.13 1.83 1.21 5.00
49 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
50 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98 5.00
51 INT163390 Il6 Positive_regulation of Gene_expression of Crp 2 0.03 3.42 0.95 5.00
52 INT166983 Binding of HLA-B and HSPG2 4 0.08 4.66 0.88 5.00
53 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86 5.00
54 INT265566 Binding of PDE4D and PTPN5 1 0.03 0.81 0.85 5.00
55 INT302379 Crp Positive_regulation of Gene_expression of Ccl2 1 0.10 4.58 0.84 5.00
56 INT240619 Binding of CRP and ADIPOQ 8 0.18 10.74 0.78 5.00
57 INT298730 PROC Positive_regulation of Gene_expression of Ngf 1 0.00 0.6 0.74 5.00
58 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69 5.00
59 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67 5.00
60 INT329589 Serpina5 Positive_regulation of PTX3 1 0.03 1.52 0.66 5.00
61 INT191494 IL6 Positive_regulation of Binding of CRP 1 0.02 1.65 0.65 5.00
62 INT311470 Binding of Crp and Il1 1 0.00 2.44 0.63 5.00
63 INT311466 Binding of Acsl1 and Il1 1 0.00 2.46 0.63 5.00
64 INT333165 Binding of asa and Col7a1 1 0.03 0.94 0.63 5.00
65 INT174860 VEGFA Positive_regulation of Localization of CCL2 1 0.21 1.68 0.63 5.00
66 INT311467 Binding of Crp and Acsl1 1 0.00 2.31 0.61 5.00
67 INT181491 Tryptase Positive_regulation of HTR1A 1 0.02 0.93 0.61 5.00
68 INT298729 PROC Positive_regulation of Set 1 0.00 0.76 0.55 5.00
69 INT333168 Tlx2 Negative_regulation of Gene_expression of Vcam1 1 0.14 0.71 0.51 5.00
70 INT248135 Binding of IDS and ACCS 1 0.09 1.12 0.51 5.00
71 INT333160 asa Negative_regulation of Gene_expression of Vcam1 1 0.19 0.71 0.5 5.00
72 INT329587 Binding of PTX3 and HEY1 1 0.00 2.03 0.5 5.00
73 INT274625 OPN1MW Positive_regulation of SOD1 1 0.19 0.29 0.5 5.00
74 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5 5.00
75 INT333151 asa Regulation of Gene_expression of Icam1 1 0.09 0.59 0.48 5.00
76 INT333156 Tlx2 Regulation of Gene_expression of Icam1 1 0.06 0.59 0.48 5.00
77 INT114754 Il6 Positive_regulation of Gene_expression of Crp 2 0.08 1.67 0.47 5.00
78 INT333161 asa Negative_regulation of Positive_regulation of Vcam1 1 0.22 0.57 0.47 5.00
79 INT344709 Niacr1 Positive_regulation of Hdl1 1 0.32 2.74 0.46 5.00
80 INT246938 Binding of Tlr4 and Tlr2 3 0.39 2.88 0.46 5.00
81 INT22674 Binding of SERPINE1 and PLAT 7 0.04 0.65 0.45 5.00
82 INT191493 Binding of AGTR1 and NLRP3 2 0.03 2.35 0.39 5.00
83 INT173977 Binding of TNF and Ighg1 1 0.03 0.28 0.39 5.00
84 INT181862 Binding of MPO and PRTN3 2 0.16 1.18 0.38 5.00
85 INT229292 FXR1 Regulation of Gene_expression of FGF19 1 0.08 1.14 0.37 5.00
86 INT226785 Angpt2 Positive_regulation of Localization of Lep 1 0.01 1.65 0.36 5.00
87 INT344238 MCRS1 Regulation of TREX1 1 0.08 1.02 0.34 5.00
88 INT236955 Binding of Cxcr5 and Cxcl13 1 0.28 2.26 0.34 5.00
89 INT318299 Binding of F2 and PRTN3 1 0.01 1.92 0.33 5.00
90 INT333154 Tlx2 Regulation of Gene_expression of asa 1 0.07 0.18 0.32 5.00
91 INT333163 asa Regulation of Gene_expression of Tlx2 1 0.07 0.18 0.32 5.00
92 INT333158 asa Positive_regulation of Nos3 1 0.11 0.18 0.32 5.00
93 INT333166 Tlx2 Positive_regulation of Gene_expression of Nos3 1 0.08 0.18 0.32 5.00
94 INT277011 CRP Positive_regulation of Gene_expression of F3 1 0.06 1.03 0.32 5.00
95 INT333155 Tlx2 Regulation of Gene_expression of Nos3 1 0.08 0.18 0.32 5.00
96 INT333152 Tlx2 Positive_regulation of Nos3 1 0.08 0.18 0.32 5.00
97 INT333169 asa Positive_regulation of Gene_expression of Nos3 1 0.11 0.18 0.32 5.00
98 INT333164 asa Regulation of Nos3 1 0.11 0.18 0.32 5.00
99 INT333149 asa Regulation of Gene_expression of Nos3 1 0.11 0.18 0.32 5.00
100 INT333167 Tlx2 Regulation of Nos3 1 0.08 0.18 0.32 5.00
101 INT342457 CSF1 Negative_regulation of Gene_expression of CCR4 1 0.00 0.93 0.31 5.00
102 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31 5.00
103 INT191499 CMA1 Positive_regulation of NLRP3 1 0.02 0.42 0.3 5.00
104 INT191502 Binding of CMA1 and NLRP3 1 0.01 0.42 0.3 5.00
105 INT265826 Binding of ACE and SERPINE1 1 0.24 1.08 0.3 5.00
106 INT299956 Binding of PPARA and EPC1 1 0.09 0.34 0.29 5.00
107 INT191501 NLRP3 Positive_regulation of ECE1 1 0.01 1.09 0.28 5.00
108 INT191505 NLRP3 Positive_regulation of Protein_catabolism of EDN1 1 0.00 1.1 0.28 5.00
109 INT333159 Tlx2 Negative_regulation of Gene_expression of Thbd 1 0.12 0.53 0.28 5.00
110 INT182499 Binding of AGTR1 and AGTR2 3 0.20 2.79 0.28 5.00
111 INT229332 BAS Negative_regulation of Pck1 1 0.01 0.2 0.28 5.00
112 INT344704 Positive_regulation of Ppara Positive_regulation of Binding of Hdl1 1 0.13 0.83 0.28 5.00
113 INT333153 asa Negative_regulation of Gene_expression of Thbd 1 0.16 0.53 0.28 5.00
114 INT191495 NLRP3 Positive_regulation of Protein_catabolism of ECE1 1 0.01 1.09 0.28 5.00
115 INT344715 Positive_regulation of Ppara Positive_regulation of Gene_expression of Pltp 1 0.02 0.83 0.28 5.00
116 INT265831 BGN Positive_regulation of ADCY1 1 0.01 0.41 0.27 5.00
117 INT342458 CSF1 Positive_regulation of Gene_expression of CCL2 1 0.17 0.84 0.27 5.00
118 INT191503 CD40LG Regulation of Gene_expression of F3 1 0.01 0.99 0.27 5.00
119 INT191497 Binding of REN and NLRP3 1 0.02 0.55 0.27 5.00
120 INT265830 KNG1 Positive_regulation of Localization of BGN 1 0.02 0.33 0.27 5.00
121 INT191504 CPN2 Positive_regulation of NLRP3 1 0.00 0.37 0.27 5.00
122 INT177961 Binding of CCR3 and CCL11 1 0.04 0.73 0.26 5.00
123 INT281005 Hdlcl1 Regulation of OTOR 1 0.00 1.62 0.26 5.00
124 INT342456 AGT Positive_regulation of Gene_expression of CCL2 1 0.07 0.63 0.25 5.00
125 INT177957 CCL11 Regulation of Binding of IL5 and CCL11 1 0.01 0.71 0.25 5.00
126 INT191498 Binding of CTSG and NLRP3 1 0.07 0.37 0.25 5.00
127 INT177960 Binding of IL5 and CCL11 1 0.03 0.71 0.25 5.00
128 INT329586 Binding of UBAP1 and ACCS 1 0.00 1.08 0.25 5.00
129 INT191496 CTSG Positive_regulation of NLRP3 1 0.09 0.37 0.25 5.00
130 INT191500 ACE Positive_regulation of Localization of KNG1 1 0.10 0.17 0.24 5.00
131 INT287794 Binding of IGHG3 and AIP 1 0.05 2.8 0.24 5.00
132 INT191536 Klk1c2 Positive_regulation of NLRP3 1 0.02 0.36 0.24 5.00
133 INT191537 Binding of Klk1c2 and NLRP3 1 0.02 0.36 0.24 5.00
134 INT191492 Binding of AGT and NLRP3 1 0.01 0.35 0.23 5.00
135 INT344714 Nr1h4 Negative_regulation of Gene_expression of Lipg 1 0.02 0.77 0.23 5.00
136 INT318174 Binding of Crp and Xcl1 1 0.03 1.9 0.22 5.00
137 INT354544 Avp Positive_regulation of ADCY1 1 0.24 2.23 0.22 5.00
138 INT318303 Negative_regulation of Myoz1 Negative_regulation of Transcription of IL2 1 0.00 0.75 0.21 5.00
139 INT306178 Rhoa Positive_regulation of Rock2 2 0.40 1.04 0.21 5.00
140 INT174861 Binding of FGF2 and VEGFA 1 0.34 0.59 0.2 5.00
141 INT177962 IL4 Positive_regulation of VCAM1 1 0.02 0.97 0.2 5.00
142 INT333171 Tlx2 Positive_regulation of Blnk 1 0.03 0.37 0.19 5.00
143 INT333170 asa Positive_regulation of Blnk 1 0.07 0.38 0.19 5.00
144 INT217661 LEP Positive_regulation of INS 2 0.25 1.85 0.19 5.00
145 INT217665 ADIPOQ Positive_regulation of INS 2 0.06 1.8 0.19 5.00
146 INT126944 Binding of PKD2 and Pkd1 2 0.08 2.09 0.19 5.00
147 INT318298 MECOM Negative_regulation of Binding of CD28 1 0.00 1.08 0.18 5.00
148 INT213072 Binding of IFNA1 and ACCS 1 0.06 3.85 0.17 5.00
149 INT291041 IL6 Regulation of IL36RN 1 0.00 1.09 0.17 5.00
150 INT277013 PLAT Positive_regulation of Gene_expression of F13A1 1 0.02 0.31 0.17 5.00
151 INT229289 FGF19 Negative_regulation of CYP7A1 1 0.26 0.32 0.16 5.00
152 INT191355 HDAC4 Positive_regulation of Gene_expression of Shc1 1 0.02 1.07 0.16 5.00
153 INT302381 Il33 Regulation of Gene_expression of Il4 1 0.01 0.76 0.16 5.00
154 INT191354 Negative_regulation of HDAC4 Positive_regulation of Gene_expression of Shc1 1 0.02 1.07 0.16 5.00
155 INT277012 Binding of PAPPA and ACE2 1 0.02 1.26 0.15 5.00
156 INT344721 Binding of AHA and Hdl1 1 0.02 1.16 0.15 5.00
157 INT217667 LEP Negative_regulation of Localization of INS 1 0.15 1.18 0.14 5.00
158 INT344707 Scarb1 Positive_regulation of Positive_regulation of Hdl1 1 0.14 0.88 0.14 5.00
159 INT257937 Binding of CSF2 and INVS 1 0.04 1.1 0.14 5.00
160 INT217664 LEP Negative_regulation of INS 1 0.15 1.18 0.14 5.00
161 INT344710 Lipc Positive_regulation of Positive_regulation of Hdl1 1 0.04 0.87 0.14 5.00
162 INT239317 Egfl7 Positive_regulation of Hdl1 2 0.01 2.3 0.14 5.00
163 INT229290 BAS Negative_regulation of LDLR 1 0.03 0.83 0.13 5.00
164 INT267973 Binding of CHKB and ESR1 1 0.02 1.67 0.13 5.00
165 INT258016 AGTR1 Positive_regulation of EGFR 1 0.15 1.24 0.13 5.00
166 INT290194 Binding of PLTP and Hdl1 1 0.07 7.3 0.13 5.00
167 INT344705 Nr1h2 Regulation of Scarb1 1 0.04 1.53 0.12 5.00
168 INT344706 Nr1h2 Regulation of Abca1 1 0.03 2.39 0.12 5.00
169 INT267927 asa Negative_regulation of Gene_expression of Tbxa2r 1 0.00 0.78 0.12 5.00
170 INT344713 Nr1h2 Regulation of Abcg1 1 0.03 2.39 0.12 5.00
171 INT221989 Cpn1 Positive_regulation of Localization of Ccl2 1 0.07 1.6 0.12 5.00
172 INT342459 CXCR3 Positive_regulation of CRTC1 1 0.00 0.59 0.11 5.00
173 INT229287 BAS Negative_regulation of CRP 1 0.04 0.36 0.11 5.00
174 INT229286 BAS Negative_regulation of FXR1 1 0.02 0.55 0.09 5.00
175 INT199667 Cep290 Regulation of Atf4 1 0.04 1.96 0.09 5.00
176 INT277890 Binding of Ids and Tas2r111-ps2 1 0.08 0.5 0.09 5.00
177 INT223088 Binding of ELF3 and NAGLU 1 0.14 0.84 0.09 5.00
178 INT277889 Regulation of Binding of Ids and Tas2r111-ps2 1 0.09 0.5 0.09 5.00
179 INT265829 ACE Positive_regulation of Protein_catabolism of KNG1 1 0.33 0.73 0.09 5.00
180 INT223089 Binding of IDS and NAGLU 1 0.26 0.72 0.09 5.00
181 INT229274 BAS Positive_regulation of BAS Negative_regulation of FXR1 1 0.00 0.55 0.09 5.00
182 INT199666 Cntln Regulation of Atf4 1 0.00 1.95 0.09 5.00
183 INT291040 Binding of CFH and INS 1 0.25 1.32 0.08 5.00
184 INT277010 Binding of PAPPA and TNNT1 1 0.24 0.99 0.07 5.00
185 INT336341 Binding of RTCA and ELOVL1 1 0.02 2.15 0.07 5.00
186 INT262997 Binding of HSD11B1 and ADIPOQ 1 0.54 2.82 0.07 5.00
187 INT229330 Binding of Nr1h2 and Positive_regulation of Gene_expression of GCK 1 0.01 0.62 0.07 5.00
188 INT229333 Binding of Nr1h2 and Positive_regulation of Gene_expression of SLC2A4 1 0.02 0.62 0.07 5.00
189 INT172382 AGT Positive_regulation of Localization of EDN1 1 0.03 0.34 0.07 5.00
190 INT258021 Positive_regulation of Binding of CDK2 and CDKN1A 1 0.11 0.84 0.07 5.00
191 INT226787 Trglyd Positive_regulation of Lbp 1 0.04 1.67 0.07 5.00
192 INT172381 AVP Positive_regulation of Localization of EDN1 1 0.01 0.34 0.07 5.00
193 INT277016 Binding of MB and PAPPA 1 0.10 1 0.07 5.00
194 INT226786 Scl1 Positive_regulation of Lbp 1 0.04 1.68 0.07 5.00
195 INT353489 Negative_regulation of Aldh2 Negative_regulation of Prkag1 1 0.00 0.84 0.07 5.00
196 INT229291 BAS Positive_regulation of HSD11B1 1 0.09 0.22 0.06 5.00
197 INT224922 Binding of FAP and TARM1 1 0.06 1.4 0.06 5.00
198 INT344719 Hdl1 Positive_regulation of Plat 1 0.10 1.23 0.05 5.00
199 INT258015 Binding of ANGPT2 and REN 1 0.01 0.59 0.05 5.00
200 INT229288 Binding of FXR1 and BAS 1 0.01 0.59 0.05 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Pathologic Constriction. They are ordered first by their pain relevance and then by number of times they were reported in Pathologic Constriction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT39948 Binding of FLNA 45 0.42 58.05 4.27 100.00
2 INT9973 Binding of MMVP1 14 0.48 22.66 1.79 100.00
3 INT3404 Binding of BCAR1 10 0.33 7.97 1.33 100.00
4 INT38595 Localization of BCAR1 8 0.73 2.9 6.25 100.00
5 INT237274 Binding of C11orf2 1 0.18 0.71 0 100.00
6 INT60279 Gene_expression of VHL 70 0.78 75.21 2.21 100.00
7 INT174592 Localization of GLG1 7 0.71 4.71 1.22 100.00
8 INT74016 Binding of VHL 20 0.48 15.49 0.54 100.00
9 INT129876 Negative_regulation of Positive_regulation of CTSS 1 0.43 1.88 0.17 100.00
10 INT287799 Positive_regulation of Gene_expression of AIP 1 0.42 7.39 1.19 100.00
11 INT121677 Gene_expression of Srms 6 0.59 3.15 1.61 99.98
12 INT34870 Positive_regulation of OPA1 18 0.59 10.66 5 99.98
13 INT53447 Negative_regulation of DLD 17 0.54 12.9 2.48 99.96
14 INT19716 Gene_expression of Ecd 9 0.41 2.18 0.57 99.96
15 INT218334 Localization of Lima1 1 0.55 0.81 0.12 99.92
16 INT197064 Positive_regulation of sWSS86 1 0.02 1.04 0 99.90
17 INT159690 Gene_expression of Atp6v0c-ps2 1 0.38 0.83 0 99.90
18 INT101441 Positive_regulation of FTH1 15 0.54 7.03 3.22 99.76
19 INT756 Gene_expression of C3 138 0.75 100.6 19.2 99.72
20 INT10890 Binding of F8 11 0.36 7.27 1.15 99.72
21 INT233945 Positive_regulation of Expi 5 0.04 2.53 3.46 99.64
22 INT1179 Negative_regulation of Ace 157 0.59 67.03 30.46 99.62
23 INT12771 Positive_regulation of IKBKG 27 0.69 5.99 7.02 99.60
24 INT154867 Gene_expression of CECR 28 0.57 6.97 3.72 99.58
25 INT312566 Positive_regulation of Gene_expression of CECR 1 0.19 1.67 0.38 99.58
26 INT45147 Gene_expression of C2 21 0.58 6.18 3.98 99.56
27 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 99.52
28 INT1922 Positive_regulation of CEACAM7 32 0.70 33.31 2.72 99.52
29 INT67188 Gene_expression of OPLL 10 0.52 4.58 1.12 99.48
30 INT2055 Regulation of Gnrh1 185 0.62 23.65 71.26 99.48
31 INT145760 Binding of Tlr2 5 0.46 3.59 0.89 99.48
32 INT21687 Positive_regulation of ras 143 0.58 97.34 27.31 99.46
33 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01 99.44
34 INT16395 Gene_expression of CEBPZ 30 0.57 11.02 6.66 99.44
35 INT170854 Gene_expression of CFD 26 0.68 39.77 4.74 99.44
36 INT113948 Gene_expression of FLNA 32 0.73 36.06 4.81 99.40
37 INT16396 Negative_regulation of CEBPZ 76 0.48 30.03 21.6 99.38
38 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71 99.34
39 INT72182 Gene_expression of Mcpt1 167 0.75 123.7 52.15 99.34
40 INT180379 Gene_expression of Olr1 31 0.36 36.46 4.84 99.34
41 INT75908 Regulation of LEP 77 0.60 60.16 15.19 99.30
42 INT19768 Negative_regulation of LAMC2 11 0.57 10.54 5.32 99.20
43 INT226997 Gene_expression of CLNS1A 2 0.04 0.45 0.05 99.20
44 INT4047 Binding of F13A1 105 0.43 66.54 11.81 99.16
45 INT238041 Binding of OPLL 7 0.27 2.95 0.54 99.16
46 INT8684 Positive_regulation of ANGPTL5 45 0.69 36.29 7.47 99.14
47 INT30610 Localization of PCa 35 0.65 13.91 4.25 99.10
48 INT677 Positive_regulation of CST3 20 0.67 17.47 6 99.02
49 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 99.00
50 INT9664 Binding of LBP 127 0.48 94.9 63.42 98.96
51 INT117307 Negative_regulation of PRG2 1 0.12 0.39 0.54 98.96
52 INT624 Positive_regulation of GAST 28 0.70 15.61 4.73 98.94
53 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 98.92
54 INT32420 Binding of Cir1 1 0.47 1.33 0.06 98.92
55 INT257363 Positive_regulation of TIA1 1 0.12 0.78 0 98.88
56 INT322080 Regulation of Binding of Ecd 1 0.03 1.38 0.21 98.88
57 INT102470 Negative_regulation of Pvr 3 0.37 2.36 0.32 98.86
58 INT291342 Negative_regulation of Mpeg1 3 0.40 5.76 0.2 98.84
59 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 98.80
60 INT139795 Negative_regulation of IKBKG 2 0.21 1.14 0.15 98.78
61 INT156639 Localization of Hcm 5 0.64 7.65 0.16 98.76
62 INT22708 Gene_expression of MUC1 297 0.78 232.71 24.19 98.72
63 INT83837 Gene_expression of CEACAM6 7 0.76 13.8 4.59 98.72
64 INT84809 Positive_regulation of Gene_expression of MUC1 39 0.70 36.42 3.75 98.72
65 INT156485 Positive_regulation of Gene_expression of CEACAM6 3 0.49 6.5 1.54 98.72
66 INT85829 Gene_expression of CA9 14 0.68 12.59 1.4 98.72
67 INT85830 Positive_regulation of Gene_expression of CA9 4 0.41 5.47 1.02 98.72
68 INT57424 Positive_regulation of TNNT1 42 0.67 31.84 9.7 98.70
69 INT169558 Positive_regulation of NF1 13 0.59 13.58 0 98.68
70 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14 98.64
71 INT167018 Negative_regulation of POR 3 0.37 1.9 0.11 98.60
72 INT106745 Localization of CRP 65 0.81 66.44 15.21 98.54
73 INT112989 Gene_expression of AIP 3 0.56 25.4 4.23 98.52
74 INT69592 Positive_regulation of PSMD1 27 0.70 17.83 18.98 98.48
75 INT59302 Positive_regulation of POR 19 0.49 15.18 1.95 98.40
76 INT103124 Regulation of Cd8a 3 0.23 1.65 0.68 98.40
77 INT129878 Positive_regulation of CTSS 6 0.70 7.86 0.97 98.36
78 INT296400 Binding of Hld 1 0.09 0.74 0 98.36
79 INT35407 Positive_regulation of C2 25 0.69 7.74 2.59 98.34
80 INT120062 Binding of AIP 4 0.42 28.86 3.91 98.32
81 INT299966 Negative_regulation of EPC1 10 0.22 8.66 1.07 98.28
82 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 98.24
83 INT196595 Regulation of Localization of CFD 1 0.39 2.03 0.04 98.24
84 INT221848 Positive_regulation of C11orf2 2 0.41 1.08 0.1 98.20
85 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 98.20
86 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 98.20
87 INT2406 Gene_expression of CCK 85 0.78 28.04 46.67 98.20
88 INT26337 Negative_regulation of Hmmr 6 0.30 1.11 4.01 98.18
89 INT64821 Positive_regulation of SLPI 11 0.67 5.08 1.48 98.16
90 INT63936 Positive_regulation of Phosphorylation of Ephb1 131 0.70 49.38 73.16 98.16
91 INT18933 Binding of GER 11 0.37 11.56 0.3 98.10
92 INT115384 Positive_regulation of Mmp9 121 0.68 94.74 43.02 98.08
93 INT160914 Positive_regulation of Positive_regulation of Mmp9 7 0.57 4.69 4.52 98.08
94 INT9257 Positive_regulation of SELPLG 5 0.45 3.57 1.16 98.04
95 INT12772 Positive_regulation of Positive_regulation of IKBKG 9 0.69 0.84 4.12 98.04
96 INT4873 Positive_regulation of FCGR3A 21 0.49 14.35 2.89 98.04
97 INT311579 Positive_regulation of Positive_regulation of FCGR3A 1 0.24 0.57 0.12 98.04
98 INT311578 Positive_regulation of Positive_regulation of SELPLG 1 0.18 0.57 0.12 98.04
99 INT49706 Positive_regulation of TNNT2 22 0.69 12.65 1.56 98.00
100 INT116249 Positive_regulation of LARS 6 0.39 4.16 0.71 97.92
101 INT196594 Localization of CFD 4 0.65 4.36 0.39 97.84
102 INT63934 Phosphorylation of Ephb1 377 0.82 150.52 188.66 97.68
103 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 97.68
104 INT79555 Positive_regulation of Ptcra 10 0.49 4.23 1.72 97.60
105 INT32692 Positive_regulation of Aif1 33 0.35 13.29 9.03 97.60
106 INT31582 Gene_expression of Hdl1 103 0.66 118.95 6.42 97.58
107 INT130760 Localization of Pcd4ts3 1 0.01 1.53 0.27 97.44
108 INT19763 Gene_expression of CTs 69 0.78 32.92 18.87 97.36
109 INT123466 Binding of T2dm2 21 0.37 34.87 2.91 97.34
110 INT67590 Gene_expression of RDBP 9 0.51 5.17 1.1 97.28
111 INT210399 Gene_expression of IGF2R 22 0.65 17.1 1.23 97.28
112 INT122811 Binding of Ecd 11 0.31 3.01 0.84 97.24
113 INT80640 Gene_expression of RPL4P5 3 0.26 1.09 0.56 97.24
114 INT248660 Localization of CERS2 1 0.47 0.26 0 97.24
115 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 97.20
116 INT112334 Regulation of NF1 18 0.52 15.85 0.34 97.16
117 INT145756 Gene_expression of Tlr2 23 0.74 20.77 5.18 97.16
118 INT18898 Positive_regulation of CHGA 38 0.67 28.99 4.86 97.10
119 INT12770 Negative_regulation of Positive_regulation of IKBKG 7 0.56 0.34 3.02 97.04
120 INT142005 Gene_expression of COL18A1 6 0.75 4.53 0.62 97.00
121 INT96269 Positive_regulation of Mcpt1 71 0.61 52.38 20.4 96.96
122 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 96.92
123 INT34585 Negative_regulation of Positive_regulation of HSD11B1 31 0.57 43.54 2.47 96.92
124 INT9650 Gene_expression of LPA 141 0.75 104.57 29 96.84
125 INT9649 Positive_regulation of LPA 105 0.69 74.75 13.89 96.84
126 INT133743 Regulation of Vcan 2 0.43 2.2 1.01 96.84
127 INT221850 Gene_expression of C11orf2 4 0.64 2.22 0.13 96.76
128 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01 96.72
129 INT11042 Localization of Tbxa2r 26 0.76 10.15 7.24 96.72
130 INT342465 Protein_catabolism of MRI1 1 0.04 0.79 0.38 96.68
131 INT70265 Regulation of MRI1 42 0.39 30.95 14.18 96.64
132 INT70600 Positive_regulation of Exo1 9 0.39 4.36 2.05 96.64
133 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 96.52
134 INT180202 Localization of MMVP1 1 0.25 1.69 0 96.48
135 INT1636 Gene_expression of Sct 58 0.77 16.14 11.57 96.48
136 INT16404 Regulation of CD4 54 0.61 33.05 10.29 96.48
137 INT174106 Binding of Renbp 18 0.24 15.82 0.58 96.44
138 INT225966 Regulation of Gene_expression of Aqp4 18 0.62 20.39 2.3 96.32
139 INT47662 Localization of CHKB 34 0.81 22.63 5.14 96.24
140 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 96.20
141 INT15474 Gene_expression of PLAUR 36 0.75 22.32 4.63 96.20
142 INT49676 Positive_regulation of TG 10 0.48 9.09 0.44 96.16
143 INT79166 Regulation of TNC 12 0.44 9.42 8.13 96.12
144 INT164252 Positive_regulation of Rip 1 0.41 0.62 0.17 96.08
145 INT200219 Positive_regulation of VHL 18 0.50 15.38 0.67 96.00
146 INT17056 Gene_expression of DLD 37 0.57 13.15 5.47 95.96
147 INT66077 Regulation of CHPT1 12 0.38 6.1 3.23 95.96
148 INT130837 Gene_expression of Aqp4 205 0.78 151.23 29.63 95.88
149 INT49593 Regulation of Prph 2 0.26 0.93 0.73 95.84
150 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 95.80
151 INT18872 Negative_regulation of Asap1 18 0.43 8.48 5.42 95.76
152 INT62071 Positive_regulation of Gene_expression of PTHLH 13 0.70 19.32 1.73 95.76
153 INT153814 Localization of LPA 19 0.65 18.25 7.68 95.76
154 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 95.72
155 INT40565 Gene_expression of SLPI 15 0.75 7.25 2.21 95.68
156 INT117172 Regulation of Hpt 7 0.41 3.39 0.52 95.64
157 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 95.60
158 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 95.56
159 INT162531 Binding of Eln 4 0.43 3.8 0.42 95.56
160 INT60115 Transcription of F8 2 0.08 3.05 0.58 95.56
161 INT311580 Positive_regulation of PEX11B 1 0.01 1.57 0.26 95.56
162 INT60110 Transcription of Serpinc1 2 0.35 1.45 0.31 95.56
163 INT117502 Positive_regulation of Adipoq 70 0.63 40.43 12.03 95.48
164 INT117499 Negative_regulation of Adipoq 28 0.56 24.15 5.07 95.48
165 INT150529 Positive_regulation of Negative_regulation of Adipoq 2 0.37 1.76 0.18 95.48
166 INT66869 Negative_regulation of EDF1 3 0.38 2.02 0.13 95.44
167 INT323928 Negative_regulation of MRM1 1 0.16 0.88 0.54 95.40
168 INT76611 Positive_regulation of Srms 5 0.59 3.21 3.04 95.36
169 INT55733 Negative_regulation of VTN 47 0.58 47.22 5.68 95.36
170 INT13960 Gene_expression of GGT6 5 0.62 4.18 3.01 95.36
171 INT131788 Positive_regulation of NPPB 87 0.67 86.1 8.81 95.28
172 INT33039 Regulation of Ptcra 3 0.04 1.16 0.37 95.28
173 INT76612 Binding of Srms 3 0.42 1.1 1.87 95.20
174 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 95.16
175 INT188396 Positive_regulation of Positive_regulation of GOPC 13 0.42 1.78 1.21 95.08
176 INT15326 Phosphorylation of Trib3 83 0.55 30.96 22.27 95.04
177 INT95767 Negative_regulation of Mmp9 72 0.57 49.14 17.1 94.96
178 INT4207 Regulation of Avp 267 0.62 63.72 115.33 94.92
179 INT7142 Positive_regulation of DLD 22 0.60 7.69 2.76 94.88
180 INT199681 Gene_expression of SERPINA5 13 0.36 15.42 1.25 94.88
181 INT9552 Positive_regulation of TNNI3 209 0.70 128.67 19.15 94.88
182 INT85652 Positive_regulation of RDBP 4 0.38 1.76 0.83 94.88
183 INT1888 Protein_catabolism of F13A1 97 0.99 63.48 14.82 94.84
184 INT97078 Positive_regulation of Entpd1 16 0.64 8.54 4.49 94.76
185 INT1361 Negative_regulation of Gnrhr 118 0.58 57.77 35.54 94.68
186 INT63365 Gene_expression of Spg21 21 0.65 12.9 7.37 94.68
187 INT17701 Gene_expression of PTHLH 103 0.78 64.23 8.85 94.64
188 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46 94.60
189 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 94.52
190 INT571 Negative_regulation of C2 9 0.43 3.93 1.54 94.44
191 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22 94.44
192 INT161574 Localization of CENPJ 7 0.73 6.11 1.54 94.32
193 INT17182 Binding of Cea 25 0.48 14.98 4.16 94.24
194 INT174851 Positive_regulation of COL5A2 46 0.54 12.73 5.48 94.16
195 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 94.12
196 INT195672 Localization of APC 7 0.74 3.76 0.3 94.12
197 INT299964 Positive_regulation of FTSJ3 1 0.08 7.32 0.98 94.12
198 INT299975 Positive_regulation of Negative_regulation of FTSJ3 1 0.05 1.16 0.08 94.12
199 INT214618 Transcription of FLNA 4 0.51 8.06 0.37 94.08
200 INT3466 Gene_expression of Ptger1 39 0.75 18.34 15.75 93.96
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