D:Pathologic Dilatation

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Disease Term
Synonyms Dilatation Pathological, DILATATIONS PATHOLOGIC, Dilatations Pathological, Ectasia, PATHOLOGIC DILATATIONS, Pathological Dilatation, Pathological Dilatations
Documents 249
Hot Single Events 47
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Pathologic Dilatation. They are ordered first by their relevance to Pathologic Dilatation and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT148379 UFM1 Positive_regulation of DLL1 1 0.00 1.13 0.63 63.48
2 INT148381 UFM1 Positive_regulation of JAG1 1 0.00 1.13 0.63 62.84
3 INT325470 MMP3 Positive_regulation of MMP9 1 0.17 0.9 0.2 58.84
4 INT273040 Vip Regulation of Bax 1 0.23 1.69 0.13 54.04
5 INT273041 Adcyap1 Regulation of Bax 1 0.21 1.69 0.13 54.04
6 INT148380 PDP1 Positive_regulation of Positive_regulation of CP 1 0.12 0.64 0.44 41.24
7 INT148378 CP Positive_regulation of NOTCH1 1 0.11 0.64 0.44 40.88
8 INT148377 PDP1 Positive_regulation of NOTCH1 1 0.44 0.64 0.44 40.72
9 INT273047 Binding of Aqp4 and Sct 1 0.04 1.41 0 13.72
10 INT273045 Vip Regulation of Adcyap1 1 0.17 0.5 0.38 5.00
11 INT190751 Adcyap1 Positive_regulation of Vipr2 2 0.16 1.02 0.36 5.00
12 INT273046 Vip Negative_regulation of Gene_expression of Adcyap1 1 0.20 1.14 0.21 5.00
13 INT273048 Adcyap1 Positive_regulation of Adcyap1r1 1 0.11 1.02 0.19 5.00
14 INT271525 ITGB1 Positive_regulation of Gopc 1 0.02 0.57 0.11 5.00
15 INT171616 Sh2d1b2 Negative_regulation of Pitm1 1 0.01 0.47 0.08 5.00
16 INT187388 Esr2 Positive_regulation of Gene_expression of Pgr 1 0.00 0.8 0.03 5.00
17 INT271519 Binding of ESB3 and FRA9C 1 0.00 0.99 0.03 5.00
18 INT271526 Binding of ESB3 and Ptk2 1 0.01 0.97 0.03 5.00
19 INT271527 Binding of ESB3 and Mapk1 1 0.01 0.98 0.03 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Pathologic Dilatation. They are ordered first by their pain relevance and then by number of times they were reported in Pathologic Dilatation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 100.00
2 INT204122 Gene_expression of GJA8 13 0.47 22.98 3.04 100.00
3 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 100.00
4 INT204121 Regulation of GJA8 1 0.27 3.52 0.21 100.00
5 INT204126 Localization of GJA8 1 0.45 2.36 0.12 100.00
6 INT204125 Positive_regulation of Negative_regulation of GJA8 1 0.30 2.4 0.13 100.00
7 INT204128 Negative_regulation of GJA8 2 0.26 2.73 0.24 100.00
8 INT135122 Binding of GJA8 3 0.11 2.08 0.97 100.00
9 INT204120 Positive_regulation of GJA8 2 0.30 1.51 0.63 100.00
10 INT204129 Positive_regulation of Gene_expression of GJA8 1 0.30 0.85 0 100.00
11 INT22781 Binding of COL7A1 76 0.48 41.59 6.66 99.96
12 INT204123 Positive_regulation of Transcription of CRP 5 0.49 8.11 0.57 99.96
13 INT23257 Regulation of CRP 127 0.62 100.05 21.87 99.84
14 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 99.68
15 INT100861 Binding of CRP 179 0.48 175.2 26.45 99.56
16 INT171576 Phosphorylation of CRP 6 0.80 5.55 1.22 99.52
17 INT3206 Positive_regulation of Got1 39 0.69 19.36 17.02 99.26
18 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 99.04
19 INT204124 Transcription of CRP 14 0.69 20.79 2.71 98.96
20 INT106745 Localization of CRP 65 0.81 66.44 15.21 98.88
21 INT93939 Binding of FBN1 4 0.33 4.05 0.67 98.64
22 INT22335 Regulation of Negative_regulation of ACE 10 0.44 7.01 1.77 98.16
23 INT204127 Regulation of Negative_regulation of EGFL7 1 0.07 2.02 0.29 98.16
24 INT111048 Binding of Bdkrb2 2 0.47 2.54 1 98.16
25 INT104221 Regulation of Gene_expression of CRP 30 0.45 20.01 4.07 98.00
26 INT153300 Negative_regulation of Gene_expression of CRP 48 0.58 39.97 7.58 97.84
27 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 97.72
28 INT191534 Negative_regulation of EGFL7 10 0.06 7.52 1.98 97.64
29 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 97.20
30 INT204119 Negative_regulation of Transcription of CRP 2 0.36 2.57 0.52 97.04
31 INT346650 Gene_expression of PLK3 1 0.47 1.48 0 96.92
32 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 94.12
33 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 93.36
34 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7 92.04
35 INT4691 Regulation of Lipg 10 0.61 4.7 1.99 90.84
36 INT41694 Transcription of Lipg 1 0.53 0.85 0.08 90.24
37 INT23621 Regulation of C4A 10 0.44 5.07 0.84 89.96
38 INT325473 Regulation of C6 1 0.01 0.91 0.2 89.96
39 INT5622 Gene_expression of Nppa 101 0.78 49.46 25.31 89.32
40 INT2364 Localization of Sct 134 0.80 26.21 41.47 86.00
41 INT1636 Gene_expression of Sct 58 0.77 16.14 11.57 84.32
42 INT68181 Binding of Nf1 6 0.48 8.14 1.88 83.56
43 INT104569 Gene_expression of Aqp2 23 0.60 16.56 12.23 83.24
44 INT111047 Negative_regulation of Gene_expression of Aqp2 3 0.34 3.56 0.09 83.24
45 INT164966 Binding of Cle 2 0.32 0.91 0.19 82.44
46 INT14916 Binding of RASA1 15 0.37 13.64 1.44 81.68
47 INT187286 Binding of HEY1 17 0.32 31.21 4.52 80.08
48 INT346648 Regulation of Transcription of SERINC1 1 0.18 1.21 0 78.36
49 INT148387 Positive_regulation of NOTCH3 1 0.55 1.23 0.61 78.20
50 INT346647 Transcription of SERINC1 1 0.27 1.19 0 76.72
51 INT68180 Regulation of Nf1 2 0.27 2.02 0.22 76.24
52 INT325474 Regulation of Regulation of MMP9 1 0.53 0.96 0.14 72.48
53 INT89282 Regulation of MMP9 39 0.60 25.45 10.34 72.04
54 INT148383 Positive_regulation of ABI3BP 1 0.03 1.17 0.6 72.00
55 INT148384 Positive_regulation of HEY1 19 0.43 29.76 5.89 71.68
56 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 69.60
57 INT68179 Gene_expression of Nf1 9 0.78 8.87 0.68 69.56
58 INT2725 Positive_regulation of FCER2 23 0.69 23.08 4.7 69.20
59 INT148386 Negative_regulation of ABI3BP 1 0.02 1.16 0.63 66.96
60 INT130098 Negative_regulation of NOTCH1 11 0.42 5.45 1.33 66.56
61 INT132315 Positive_regulation of DLL1 6 0.67 3.4 2.45 63.48
62 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 63.44
63 INT148382 Positive_regulation of JAG1 5 0.23 3.88 0.63 62.84
64 INT148385 Positive_regulation of HEY2 1 0.38 1.09 0.62 59.84
65 INT123752 Regulation of Bax 19 0.60 16.45 4 58.84
66 INT176242 Binding of Bax 10 0.42 10.18 0.52 58.84
67 INT90202 Protein_catabolism of MMP2 15 0.94 7.47 5.41 58.36
68 INT93715 Negative_regulation of MMP9 69 0.55 36.05 11.73 55.84
69 INT117033 Gene_expression of JAG1 13 0.65 11.46 1.52 55.20
70 INT26501 Positive_regulation of Gene_expression of MMP2 51 0.67 39 15.16 54.84
71 INT145929 Regulation of Bax 20 0.60 18.12 5.35 54.84
72 INT134443 Binding of Bax 10 0.47 5.62 1.84 54.84
73 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9 54.44
74 INT120823 Positive_regulation of Gene_expression of Adcyap1 10 0.68 6.71 3.22 52.20
75 INT15149 Positive_regulation of Gene_expression of Vip 2 0.44 3.53 1.25 52.20
76 INT34487 Localization of MMP2 56 0.81 31.41 23.61 52.20
77 INT203311 Positive_regulation of Gene_expression of Igfals 5 0.16 6.87 0.8 52.20
78 INT65965 Gene_expression of Adcyap1 52 0.78 22.53 13.14 52.08
79 INT15148 Gene_expression of Vip 51 0.77 25.61 18.33 51.88
80 INT99610 Localization of MMP9 126 0.79 48.46 32.67 51.64
81 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 48.76
82 INT126031 Negative_regulation of Gene_expression of MMP9 40 0.57 22.71 9.79 46.52
83 INT142908 Localization of FGFR1 18 0.38 11.46 2.57 42.56
84 INT169057 Localization of VEGFC 4 0.78 2.79 0.51 42.56
85 INT2383 Positive_regulation of CP 33 0.67 25.41 15.38 41.24
86 INT68447 Positive_regulation of PDP1 11 0.64 5.69 0.83 41.24
87 INT176618 Gene_expression of HEY1 29 0.59 36 4.37 40.40
88 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 27.28
89 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 27.28
90 INT30075 Localization of Esr2 2 0.01 0.78 0.49 26.00
91 INT104567 Gene_expression of Aqp1 47 0.78 44.84 28.68 25.00
92 INT109650 Gene_expression of Aqp4 87 0.78 51.52 20.72 24.56
93 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42 23.00
94 INT200206 Negative_regulation of Gene_expression of Igfals 4 0.21 3.83 0.5 22.60
95 INT221447 Gene_expression of SERINC1 4 0.30 2.73 0.51 22.20
96 INT3463 Gene_expression of Igfals 21 0.39 21.1 2.93 22.16
97 INT261215 Localization of Sct 2 0.44 1.01 0.17 15.16
98 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93 14.96
99 INT11303 Gene_expression of Avp 116 0.78 39.23 23.88 13.48
100 INT347287 Negative_regulation of HYOU1 1 0.01 0.51 0.03 10.64
101 INT171612 Gene_expression of Cebpz 5 0.58 2.61 0.62 6.76
102 INT39374 Gene_expression of Sct 5 0.68 1.42 3.89 6.48
103 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94 5.00
104 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132 5.00
105 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
106 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
107 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01 5.00
108 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 5.00
109 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 5.00
110 INT5623 Positive_regulation of Nppa 174 0.70 69.96 52.33 5.00
111 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16 5.00
112 INT5781 Gene_expression of Edn1 190 0.78 99.1 46 5.00
113 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 5.00
114 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
115 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65 5.00
116 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 5.00
117 INT70437 Negative_regulation of Mdk 115 0.57 41.03 35.72 5.00
118 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 5.00
119 INT1495 Positive_regulation of Rtcd1 91 0.54 22.93 32.43 5.00
120 INT9655 Regulation of Il6 98 0.62 70.92 31.95 5.00
121 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7 5.00
122 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4 5.00
123 INT145594 Gene_expression of Mtx1 64 0.57 35.33 30.35 5.00
124 INT8518 Localization of Ifng 53 0.81 36.68 24.13 5.00
125 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19 5.00
126 INT69304 Negative_regulation of Il10 47 0.59 36.88 19.79 5.00
127 INT104045 Regulation of Hand1 65 0.35 51.32 16.26 5.00
128 INT36177 Binding of Alms1 70 0.31 35.47 13.81 5.00
129 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68 5.00
130 INT35801 Regulation of Alms1 34 0.38 20.88 12.38 5.00
131 INT8629 Positive_regulation of COL7A1 72 0.69 40.66 12.09 5.00
132 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 5.00
133 INT19944 Negative_regulation of IFNG 39 0.58 22.35 10.91 5.00
134 INT25989 Localization of Vip 31 0.68 10.53 10.35 5.00
135 INT94859 Negative_regulation of Pde5a 67 0.43 33.66 10.28 5.00
136 INT68960 Gene_expression of Ptger4 42 0.67 15.75 9.64 5.00
137 INT137400 Regulation of Mtx1 16 0.52 9.19 9.45 5.00
138 INT106199 Positive_regulation of Adcyap1 32 0.68 13.68 9.14 5.00
139 INT155944 Gene_expression of Foxp3 66 0.66 24.37 9.12 5.00
140 INT22285 Negative_regulation of Mtx1 16 0.49 7.84 8.98 5.00
141 INT25392 Positive_regulation of Gene_expression of Csf2 41 0.49 34.28 8.36 5.00
142 INT725 Negative_regulation of IgG 62 0.41 37.21 8.16 5.00
143 INT35802 Positive_regulation of Vip 16 0.40 21.5 7.95 5.00
144 INT65964 Regulation of Adcyap1 13 0.45 10.1 7.54 5.00
145 INT79502 Gene_expression of Pvalb 26 0.78 2.83 7.46 5.00
146 INT6210 Binding of Nppa 39 0.47 14.35 7.21 5.00
147 INT10104 Negative_regulation of Edn1 43 0.59 15.63 7.2 5.00
148 INT8793 Gene_expression of H2 58 0.75 26.36 7.07 5.00
149 INT15147 Regulation of Vip 16 0.47 12.59 6.34 5.00
150 INT26585 Gene_expression of Vim 117 0.77 39.97 6 5.00
151 INT131378 Negative_regulation of FN1 20 0.35 33.98 5.85 5.00
152 INT25394 Negative_regulation of Gene_expression of Csf2 22 0.52 13.18 5.84 5.00
153 INT56149 Localization of CD8A 56 0.74 30.41 5.75 5.00
154 INT25991 Negative_regulation of Vip 11 0.53 6.76 4.64 5.00
155 INT44066 Gene_expression of Ltf 20 0.77 15.09 4.57 5.00
156 INT106548 Localization of Adcyap1 14 0.80 5.05 4.33 5.00
157 INT189629 Negative_regulation of TIMP3 14 0.48 7.63 3.91 5.00
158 INT115877 Negative_regulation of Adcyap1 14 0.59 5.31 3.74 5.00
159 INT81188 Gene_expression of Vipr2 16 0.78 4.38 3.7 5.00
160 INT123564 Negative_regulation of Rock2 13 0.59 9.61 3.58 5.00
161 INT37590 Regulation of COL7A1 15 0.54 9.4 3.12 5.00
162 INT27446 Negative_regulation of CTSA 11 0.57 5.58 3.08 5.00
163 INT16130 Binding of IGF1 67 0.48 27.43 2.95 5.00
164 INT152961 Negative_regulation of Gene_expression of Aqp4 13 0.59 10.01 2.92 5.00
165 INT8095 Gene_expression of ERBB3 47 0.77 24.85 2.82 5.00
166 INT142120 Gene_expression of Runx2 45 0.77 15.76 2.55 5.00
167 INT52509 Positive_regulation of Cebpz 9 0.59 2.63 2.42 5.00
168 INT131456 Negative_regulation of MMRN1 14 0.19 9.49 2.29 5.00
169 INT111741 Negative_regulation of Gene_expression of Vip 3 0.33 3.38 2.26 5.00
170 INT32781 Binding of Vip 7 0.47 4.31 1.98 5.00
171 INT206471 Positive_regulation of Ptk2 34 0.51 25.75 1.61 5.00
172 INT46640 Negative_regulation of Cebpz 9 0.37 2.67 1.52 5.00
173 INT216123 Negative_regulation of Cd68 2 0.41 1.96 1.48 5.00
174 INT24768 Negative_regulation of Gene_expression of Edn1 10 0.43 2.85 1.48 5.00
175 INT167872 Negative_regulation of Gene_expression of Foxp3 8 0.50 4.14 1.46 5.00
176 INT200189 Negative_regulation of Igfals 7 0.24 4.19 1.39 5.00
177 INT261216 Negative_regulation of Bsbob 2 0.06 3.07 1.16 5.00
178 INT273035 Regulation of Bsbob 1 0.01 3.33 1.14 5.00
179 INT78319 Binding of EPCAM 8 0.36 10.12 1.14 5.00
180 INT229562 Negative_regulation of Foxp3 6 0.36 3.7 1.14 5.00
181 INT106549 Binding of Adcyap1 3 0.35 1.83 1.08 5.00
182 INT46369 Positive_regulation of AK1 3 0.09 1.24 0.94 5.00
183 INT138683 Regulation of Ighg1 15 0.30 7.95 0.94 5.00
184 INT273038 Regulation of Vtn 3 0.08 2.26 0.91 5.00
185 INT57059 Negative_regulation of IGKC 4 0.24 1.34 0.86 5.00
186 INT32835 Negative_regulation of Pde3a 5 0.10 3.65 0.82 5.00
187 INT134207 Gene_expression of Ptk2 56 0.73 31.97 0.78 5.00
188 INT234160 Localization of Igfals 4 0.16 3.8 0.74 5.00
189 INT237158 Negative_regulation of Negative_regulation of Tnf 2 0.13 1.37 0.74 5.00
190 INT201216 Negative_regulation of LAMB2 6 0.04 3.75 0.71 5.00
191 INT2384 Regulation of CTSA 4 0.44 2.22 0.69 5.00
192 INT137222 Positive_regulation of Sh2d1b2 5 0.30 1.26 0.6 5.00
193 INT200754 Gene_expression of Rpe 35 0.51 6.3 0.58 5.00
194 INT19716 Gene_expression of Ecd 9 0.41 2.18 0.57 5.00
195 INT90416 Positive_regulation of RASA1 3 0.67 1.58 0.56 5.00
196 INT171606 Regulation of Localization of Sh2d1b2 2 0.13 0.41 0.42 5.00
197 INT171608 Localization of Sh2d1b2 2 0.21 0.4 0.42 5.00
198 INT94173 Positive_regulation of CTSA 3 0.53 3.22 0.4 5.00
199 INT271521 Phosphorylation of Ptk2 10 0.59 11.45 0.39 5.00
200 INT187778 Gene_expression of Slc11a1 12 0.33 7.37 0.35 5.00
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