D:Pelvic Organ Prolapse

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pChart

Disease Term
Synonyms ORGAN PROLAPSE PELVIC, ORGAN PROLAPSES PELVIC, Pelvic Organ Prolapses, Prolapse Pelvic Organ, PROLAPSE UROGENITAL, PROLAPSE VAGINAL VAULT, Prolapses Pelvic Organ, PROLAPSES UROGENITAL, Prolapses Vaginal Vault, Urogenital Prolapse, UROGENITAL PROLAPSES
Documents 170
Hot Single Events 11
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Pelvic Organ Prolapse. They are ordered first by their relevance to Pelvic Organ Prolapse and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT291556 Binding of ESR1 and Sec22b 2 0.00 0.86 0.5 5.00
2 INT170858 Binding of IFI27 and Ccne2 1 0.01 0.17 0 5.00
3 INT170841 Binding of CFD and IFI27 1 0.07 0.37 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Pelvic Organ Prolapse. They are ordered first by their pain relevance and then by number of times they were reported in Pelvic Organ Prolapse. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT168446 Gene_expression of Prep 25 0.64 15.17 5.94 100.00
2 INT227524 Positive_regulation of Gene_expression of Prep 13 0.48 7.69 3.28 100.00
3 INT61340 Regulation of Prep 7 0.50 6.13 2.31 100.00
4 INT305227 Negative_regulation of Gene_expression of Prep 2 0.11 1.42 0.1 100.00
5 INT227424 Binding of Prep 6 0.35 2.61 1.39 100.00
6 INT57064 Positive_regulation of APC 72 0.66 48.5 5.08 99.98
7 INT134482 Negative_regulation of MMVP1 1 0.00 0.98 0.09 98.08
8 INT80420 Gene_expression of IFI27 145 0.78 63.61 8.83 97.40
9 INT253294 Positive_regulation of Oca2 5 0.11 1.62 0.13 92.08
10 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 81.68
11 INT170851 Localization of IFI27 1 0.70 0.65 0 80.16
12 INT94408 Positive_regulation of Gene_expression of IFI27 28 0.65 12.89 3.53 76.52
13 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 75.16
14 INT98782 Gene_expression of Cdkn1b 70 0.75 36.43 1.9 73.24
15 INT105332 Regulation of Gene_expression of IFI27 14 0.45 8.39 2.02 64.96
16 INT170852 Negative_regulation of Gene_expression of IFI27 16 0.55 8.62 0.05 63.52
17 INT170853 Positive_regulation of Gene_expression of CFD 7 0.23 9.89 1.41 54.92
18 INT170854 Gene_expression of CFD 26 0.68 39.77 4.74 53.88
19 INT198101 Negative_regulation of AVSD1 2 0.19 0.89 0.08 53.60
20 INT198102 Gene_expression of AVSD1 2 0.30 0.71 0.07 50.00
21 INT36798 Gene_expression of Mki67 178 0.77 132 8.24 34.68
22 INT252951 Localization of Oca2 2 0.17 1.53 0.23 32.28
23 INT178962 Gene_expression of Oca2 15 0.19 5.15 0.38 23.84
24 INT1047 Negative_regulation of LH 314 0.59 53.71 135.89 5.00
25 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 5.00
26 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
27 INT2056 Negative_regulation of Gnrh1 175 0.59 33.43 63.32 5.00
28 INT20462 Binding of ESR1 210 0.44 102.7 26.34 5.00
29 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52 5.00
30 INT92354 Localization of ESR1 77 0.75 33.04 15.51 5.00
31 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 5.00
32 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 5.00
33 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15 5.00
34 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 5.00
35 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18 5.00
36 INT32203 Negative_regulation of Crp 48 0.58 32.77 11.89 5.00
37 INT2160 Negative_regulation of Negative_regulation of LH 22 0.58 4.58 11.53 5.00
38 INT15687 Regulation of ESR1 91 0.60 40.42 7.95 5.00
39 INT102572 Gene_expression of Ccnd1 79 0.69 56.37 7.34 5.00
40 INT31333 Gene_expression of Esr2 19 0.69 8.78 6.83 5.00
41 INT32107 Gene_expression of PTPLA 14 0.47 8.06 6.76 5.00
42 INT188844 Gene_expression of AES 44 0.58 33.94 5.85 5.00
43 INT201130 Localization of AES 31 0.63 25.45 5.12 5.00
44 INT170604 Negative_regulation of Gene_expression of GOPC 50 0.35 12.71 4.51 5.00
45 INT80421 Positive_regulation of IFI27 26 0.65 15.32 3.93 5.00
46 INT11261 Positive_regulation of PTPLA 3 0.50 4.4 3.74 5.00
47 INT20461 Binding of Esr1 34 0.48 9.58 3.66 5.00
48 INT16165 Regulation of DMD 114 0.60 35.13 3.64 5.00
49 INT178631 Phosphorylation of ESR1 21 0.75 9.16 3.36 5.00
50 INT171998 Binding of DMD 58 0.47 38.13 3.35 5.00
51 INT10070 Negative_regulation of Fshb 13 0.42 3.48 2.5 5.00
52 INT123016 Gene_expression of Sec22b 11 0.41 5.1 2.5 5.00
53 INT106607 Protein_catabolism of IFI27 6 0.93 1.76 2.01 5.00
54 INT197889 Binding of Sec22b 7 0.04 4.38 1.46 5.00
55 INT180580 Binding of HEYL 7 0.17 4.49 1.15 5.00
56 INT38373 Positive_regulation of Ap3b1 4 0.37 1.01 0.86 5.00
57 INT11949 Negative_regulation of Apob 11 0.09 8.13 0.85 5.00
58 INT124850 Gene_expression of Tpt1 42 0.77 14.51 0.79 5.00
59 INT80122 Gene_expression of ESRRB 4 0.41 2.21 0.78 5.00
60 INT106621 Negative_regulation of Protein_catabolism of IFI27 3 0.40 0.49 0.76 5.00
61 INT140637 Negative_regulation of IFI27 11 0.40 9.48 0.69 5.00
62 INT106613 Regulation of IFI27 6 0.57 3.12 0.66 5.00
63 INT176586 Positive_regulation of Binding of ESR1 11 0.41 4.64 0.33 5.00
64 INT166958 Gene_expression of LYRM4 4 0.18 2.9 0.27 5.00
65 INT170847 Gene_expression of Ccne2 6 0.58 2.98 0.21 5.00
66 INT170849 Binding of Cdk4 3 0.16 2.44 0.1 5.00
67 INT320132 Positive_regulation of Binding of Sec22b 1 0.02 0.73 0.09 5.00
68 INT320131 Positive_regulation of Gene_expression of Sec22b 1 0.02 0.69 0.08 5.00
69 INT216691 Gene_expression of CASK 1 0.06 1.32 0.05 5.00
70 INT170857 Negative_regulation of Gene_expression of ESRRB 1 0.01 0.18 0 5.00
71 INT170856 Binding of IFI27 4 0.35 1.14 0 5.00
72 INT306141 Binding of Oca2 1 0.10 0.17 0 5.00
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