D:Periodontal Disease

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Disease Term
Synonyms Disease Of Supporting Structures Of Teeth, Disease Periodontal, DISEASES PERIODONTAL, Parodontoses, Parodontosis, Periodontal Diseases, Periodontal Disorder, Periodontal Disorders, Periodontium Disorder, Periodontium Disorders, Pyorrhea Alveolaris
Documents 467
Hot Single Events 196
Hot Interactions 16

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Periodontal Disease. They are ordered first by their relevance to Periodontal Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT329342 Binding of THAS and LRRFIP1 1 0.00 0.97 0.09 100.00
2 INT65015 IL6 Negative_regulation of Gene_expression of PTGER2 1 0.09 0.17 0.24 99.50
3 INT65011 IL1B Positive_regulation of PTGER2 4 0.08 0.92 0.82 95.72
4 INT61617 PTGER2 Regulation of Gene_expression of IL6 3 0.11 1.13 1.02 95.72
5 INT311265 RENBP Regulation of IL8 1 0.03 1.59 0.33 95.20
6 INT311263 RENBP Regulation of TNF 1 0.01 1.59 0.33 95.20
7 INT311266 RENBP Regulation of IL6 1 0.02 1.59 0.32 95.20
8 INT292893 TNF Regulation of IL8 2 0.27 1.3 0.63 95.20
9 INT267585 TNF Regulation of IL6 2 0.16 2.44 0.37 95.20
10 INT311268 RENBP Regulation of Gene_expression of IL8 1 0.02 1.05 0.24 95.20
11 INT65012 IL1B Regulation of Gene_expression of IL6 1 0.25 0.16 0.23 95.08
12 INT311267 RENBP Regulation of Gene_expression of TNF 1 0.02 0.54 0.09 95.04
13 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17 92.36
14 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17 89.96
15 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15 88.88
16 INT65014 SOS1 Positive_regulation of Gene_expression of IL6 1 0.45 0.42 0.6 82.72
17 INT135180 IL1B Positive_regulation of Gene_expression of TNFSF11 2 0.76 1.73 0.75 78.92
18 INT302379 Crp Positive_regulation of Gene_expression of Ccl2 1 0.10 4.58 0.84 77.92
19 INT65013 SOS1 Positive_regulation of Gene_expression of PTGER2 1 0.09 0.16 0.22 73.84
20 INT311264 IL6 Positive_regulation of Gene_expression of PPIAP10 1 0.30 0.98 0.36 27.92
21 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 5.00
22 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
23 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85 5.00
24 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83 5.00
25 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18 5.00
26 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07 5.00
27 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 5.00
28 INT90387 ROS1 Positive_regulation of NFKB1 4 0.32 2.35 0.87 5.00
29 INT142847 IRF6 Positive_regulation of IL6 5 0.07 1.09 0.73 5.00
30 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67 5.00
31 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63 5.00
32 INT302469 F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.82 0.62 5.00
33 INT335291 SLC15A4 Negative_regulation of NFATC1 1 0.01 0.45 0.51 5.00
34 INT115186 IL6 Positive_regulation of Phosphorylation of STAT3 2 0.19 0.35 0.48 5.00
35 INT302466 Positive_regulation of F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.1 0.35 5.00
36 INT335307 SLC15A4 Regulation of TIMP1 1 0.01 0.69 0.29 5.00
37 INT302467 TIMP1 Positive_regulation of Negative_regulation of COL5A2 1 0.00 1.1 0.29 5.00
38 INT182771 ROS1 Positive_regulation of NFKB1 Positive_regulation of CRP 1 0.00 3.83 0.28 5.00
39 INT154755 Tnf Positive_regulation of Gene_expression of Ccl2 2 0.23 1.7 0.27 5.00
40 INT302468 INCENP Positive_regulation of Gene_expression of MMP9 1 0.01 0.72 0.26 5.00
41 INT128644 Binding of Icam1 and Selp 2 0.39 0.57 0.25 5.00
42 INT335346 SLC15A4 Negative_regulation of Gene_expression of Fos 1 0.02 0.23 0.23 5.00
43 INT335299 IRF6 Positive_regulation of TIMP1 1 0.03 0.21 0.19 5.00
44 INT335298 IRF6 Positive_regulation of MMP9 1 0.01 0.21 0.19 5.00
45 INT335311 Binding of IRF6 and SLC15A4 1 0.00 0.23 0.19 5.00
46 INT206089 Negative_regulation of FOSB Negative_regulation of Gene_expression of PTGS2 1 0.00 0.97 0.19 5.00
47 INT335306 IRF6 Positive_regulation of MMP3 1 0.03 0.21 0.18 5.00
48 INT335304 IRF6 Positive_regulation of Gene_expression of MMP1 1 0.01 0.21 0.18 5.00
49 INT335302 IRF6 Positive_regulation of MMP1 1 0.01 0.21 0.18 5.00
50 INT206081 IL6ST Negative_regulation of IL6 1 0.11 0.81 0.17 5.00
51 INT206059 IL6 Positive_regulation of INS 1 0.02 1.16 0.16 5.00
52 INT302381 Il33 Regulation of Gene_expression of Il4 1 0.01 0.76 0.16 5.00
53 INT267138 Binding of CDH5 and PECAM1 2 0.16 2.69 0.16 5.00
54 INT206070 ANG Positive_regulation of Transcription of IL6 1 0.05 1.5 0.15 5.00
55 INT233386 Binding of Il12a and Il12b 1 0.01 0.48 0.15 5.00
56 INT302384 IL6 Positive_regulation of Localization of Crp 1 0.10 1.39 0.15 5.00
57 INT182772 ROS1 Positive_regulation of NFKB1 Positive_regulation of IL1B 1 0.00 1.89 0.14 5.00
58 INT182773 ROS1 Positive_regulation of NFKB1 Positive_regulation of IL6 1 0.00 1.9 0.14 5.00
59 INT182780 NFKB1 Positive_regulation of IL1B 1 0.00 1.8 0.14 5.00
60 INT182782 NFKB1 Positive_regulation of IL6 1 0.00 1.8 0.14 5.00
61 INT311262 RENBP Regulation of Regulation of TNF 1 0.02 0.33 0.13 5.00
62 INT335300 SLC15A4 Regulation of CA2 1 0.00 0.19 0.12 5.00
63 INT206065 EDN1 Positive_regulation of IL6 1 0.03 0.47 0.12 5.00
64 INT335293 SLC15A4 Regulation of NA 1 0.00 0.19 0.12 5.00
65 INT233384 Il10 Negative_regulation of Il12a 1 0.01 0.54 0.11 5.00
66 INT206056 PTK2B Negative_regulation of Positive_regulation of IRF6 1 0.00 0.66 0.1 5.00
67 INT302385 Il1b Positive_regulation of Nfib Positive_regulation of Gene_expression of Ccl2 1 0.00 1.48 0.09 5.00
68 INT206042 Negative_regulation of FDPS Negative_regulation of Binding of FDPS and GGPS1 1 0.00 0 0.09 5.00
69 INT206054 RAC1 Positive_regulation of STAT3 1 0.07 0.11 0.09 5.00
70 INT302382 Il1b Positive_regulation of Gene_expression of Ccl2 1 0.00 1.39 0.09 5.00
71 INT302380 Tnf Positive_regulation of Nfib 1 0.00 1.41 0.09 5.00
72 INT206075 Negative_regulation of FDPS Negative_regulation of Binding of GGPS1 1 0.01 0 0.09 5.00
73 INT206078 Binding of FDPS and GGPS1 1 0.00 0 0.09 5.00
74 INT302383 Il1b Positive_regulation of Nfib 1 0.00 1.42 0.09 5.00
75 INT206072 ANG Positive_regulation of IL6 1 0.05 0.5 0.08 5.00
76 INT206080 ANG Regulation of Gene_expression of IL6 1 0.03 0.4 0.07 5.00
77 INT206063 ANG Positive_regulation of Gene_expression of KRT20 1 0.00 1.01 0.07 5.00
78 INT267137 ICAM1 Regulation of ITGAL 2 0.12 0.57 0.07 5.00
79 INT351001 Binding of Adh7 and Ins1 1 0.00 1.62 0.05 5.00
80 INT206087 RAC1 Positive_regulation of Gene_expression of STAT3 1 0.08 0.05 0.05 5.00
81 INT182775 Binding of PTH and ROS1 1 0.04 1.73 0.04 5.00
82 INT206083 LDLR Positive_regulation of Binding of STAT3 1 0.02 0.53 0.04 5.00
83 INT206073 Negative_regulation of RAC1 Positive_regulation of IL6 1 0.14 0.06 0.04 5.00
84 INT206067 Gene_expression of RAC1 Positive_regulation of Positive_regulation of IL6 1 0.16 0.07 0.04 5.00
85 INT206068 RAC1 Positive_regulation of IL6 1 0.16 0.06 0.04 5.00
86 INT206066 LDLR Positive_regulation of Phosphorylation of STAT3 1 0.02 0.52 0.04 5.00
87 INT335289 IRF6 Positive_regulation of Gene_expression of TIMP1 1 0.03 0.16 0.04 5.00
88 INT206071 IRF6 Positive_regulation of Positive_regulation of IL1B 1 0.00 0.58 0.03 5.00
89 INT206076 IL6 Positive_regulation of Positive_regulation of STAT3 1 0.19 0.3 0.03 5.00
90 INT206061 RAC1 Positive_regulation of Positive_regulation of STAT3 1 0.07 0.43 0.03 5.00
91 INT310804 SFTPA1 Negative_regulation of Gene_expression of Ptges2 1 0.00 0.14 0.03 5.00
92 INT240586 IRF7 Positive_regulation of Positive_regulation of IFNA1 1 0.01 0.44 0.03 5.00
93 INT233387 Binding of SPINK1 and Il12b 1 0.04 0.33 0 5.00
94 INT329340 UCN2 Positive_regulation of SOD1 1 0.02 1.12 0 5.00
95 INT206085 FDPS Positive_regulation of AGFG1 1 0.00 0.4 0 5.00
96 INT206058 EGFR Negative_regulation of Gene_expression of IL6 1 0.07 0.62 0 5.00
97 INT206079 ANG Regulation of KRT20 1 0.00 0.54 0 5.00
98 INT335303 Binding of IRF6 and MMP2 1 0.01 0 0 5.00
99 INT335312 SLC15A4 Negative_regulation of TIMP1 1 0.01 0.07 0 5.00
100 INT182784 IGF1 Positive_regulation of Gene_expression of INS 1 0.02 1.87 0 5.00
101 INT354919 Uvbs1 Positive_regulation of Binding of VDR and Uvbs1 1 0.00 0.13 0 5.00
102 INT206069 ANG Positive_regulation of Gene_expression of IL6 1 0.05 0.51 0 5.00
103 INT182804 Binding of ETV3 and T2DM 1 0.10 2.62 0 5.00
104 INT354923 Binding of VDR and Uvbs1 1 0.00 0.83 0 5.00
105 INT193308 Binding of PRNP and TGFB1 1 0.01 0 0 5.00
106 INT206088 IL6 Positive_regulation of JAK1 1 0.18 0.05 0 5.00
107 INT335295 SLC15A4 Negative_regulation of MMP9 1 0.00 0.07 0 5.00
108 INT206178 Foxm1 Positive_regulation of Protein_catabolism of Olr1 1 0.00 0.47 0 5.00
109 INT335309 IRF6 Positive_regulation of Gene_expression of MMP3 1 0.03 0.07 0 5.00
110 INT206086 LDLR Positive_regulation of Localization of IL6 1 0.03 0.42 0 5.00
111 INT206060 FDPS Positive_regulation of AKT1 1 0.00 0.4 0 5.00
112 INT206055 F2 Positive_regulation of Gene_expression of IL6 1 0.01 1.24 0 5.00
113 INT206082 IL6 Positive_regulation of Gene_expression of CCL2 1 0.07 0.3 0 5.00
114 INT335292 IRF6 Positive_regulation of Localization of MMP1 1 0.01 0.06 0 5.00
115 INT329341 UCN2 Positive_regulation of THAS 1 0.00 1.12 0 5.00
116 INT335305 SLC15A4 Negative_regulation of MMP3 1 0.01 0.07 0 5.00
117 INT335288 SLC15A4 Negative_regulation of IRF6 Positive_regulation of MMP9 1 0.00 0.07 0 5.00
118 INT206180 Foxm1 Positive_regulation of Transcription of Olr1 1 0.00 0.48 0 5.00
119 INT121152 Tlr4 Negative_regulation of Gene_expression of Runx1t1 1 0.00 0.07 0 5.00
120 INT335301 Binding of MMP2 and SLC15A4 1 0.00 0 0 5.00
121 INT182778 IGF1 Positive_regulation of Gene_expression of ETV3 1 0.03 1.89 0 5.00
122 INT267136 Binding of CD44 and FN1 2 0.04 0.56 0 5.00
123 INT255385 Binding of COL1A2 and DSPP 1 0.40 0.12 0 5.00
124 INT206077 RAC1 Positive_regulation of Phosphorylation of STAT3 1 0.07 0.35 0 5.00
125 INT335310 SLC15A4 Negative_regulation of Gene_expression of MMP1 1 0.00 0.07 0 5.00
126 INT255384 Binding of AKR1C2 and DSG1 1 0.01 1.54 0 5.00
127 INT335290 SLC15A4 Positive_regulation of Localization of MMP1 1 0.00 0.06 0 5.00
128 INT335297 IRF6 Positive_regulation of Gene_expression of MMP2 1 0.01 0.07 0 5.00
129 INT135179 DCSTAMP Positive_regulation of Gene_expression of TNFSF11 1 0.06 0 0 5.00
130 INT182774 Binding of ETV3 and SAE1 1 0.00 1.17 0 5.00
131 INT335308 SLC15A4 Negative_regulation of MMP1 1 0.00 0.07 0 5.00
132 INT182783 INS Positive_regulation of Gene_expression of ETV3 1 0.01 1.89 0 5.00
133 INT310805 MAPK8 Regulation of Regulation of Ptges2 1 0.01 0 0 5.00
134 INT335296 IRF6 Positive_regulation of Localization of SLC15A4 1 0.00 0.06 0 5.00
135 INT206181 FDPS Positive_regulation of ras 1 0.00 0.4 0 5.00
136 INT182777 IAPP Positive_regulation of Gene_expression of ETV3 1 0.06 1.88 0 5.00
137 INT182776 IAPP Positive_regulation of Gene_expression of INS 1 0.03 1.87 0 5.00
138 INT351002 Binding of Adh7 and Mrgpre 1 0.00 3.65 0 5.00
139 INT193307 Binding of PDGFA and PRNP 1 0.01 0 0 5.00
140 INT206084 EGF Negative_regulation of Gene_expression of IL6 1 0.05 0.61 0 5.00
141 INT335294 IRF6 Positive_regulation of Gene_expression of MMP9 1 0.01 0.07 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Periodontal Disease. They are ordered first by their pain relevance and then by number of times they were reported in Periodontal Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67 100.00
2 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 99.90
3 INT25152 Gene_expression of SAA1 37 0.75 53.56 8.07 99.76
4 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 99.76
5 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 99.76
6 INT45975 Positive_regulation of SAA1 17 0.67 19.7 4.15 99.74
7 INT166356 Negative_regulation of HSPD1 4 0.55 3 0.23 99.66
8 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 99.64
9 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 99.62
10 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 99.52
11 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 99.50
12 INT251907 Negative_regulation of Positive_regulation of MMP8 1 0.00 1.23 0.26 99.36
13 INT110806 Positive_regulation of Mmp8 7 0.46 1.64 0.67 99.36
14 INT95632 Positive_regulation of MMP8 26 0.70 10.06 9.96 99.36
15 INT164066 Negative_regulation of SIL1 3 0.21 2.75 0.96 99.36
16 INT215369 Negative_regulation of SCAP 1 0.00 0.7 0.2 99.36
17 INT215366 Gene_expression of HSPE1 12 0.74 6.39 1.39 99.32
18 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.30
19 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 99.30
20 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 99.26
21 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 99.26
22 INT91906 Regulation of Gene_expression of Il10 13 0.58 8.92 7.06 99.24
23 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 99.00
24 INT179686 Regulation of Gene_expression of COPD 10 0.34 14.1 1.52 99.00
25 INT57274 Positive_regulation of Gene_expression of COL7A1 50 0.69 24.19 4.72 98.96
26 INT215361 Regulation of HSPE1 1 0.43 1.4 0.34 98.40
27 INT3950 Gene_expression of Ptger2 293 0.77 122.28 62.42 98.32
28 INT125247 Negative_regulation of Mmp9 42 0.43 23.68 9.37 98.32
29 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 98.20
30 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 98.20
31 INT5905 Negative_regulation of ELANE 113 0.59 47.43 22.09 98.16
32 INT235200 Positive_regulation of Negative_regulation of ELANE 3 0.38 1.68 0.46 98.16
33 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 98.14
34 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47 98.04
35 INT215360 Binding of HSPE1 1 0.36 3.63 0.92 98.00
36 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 97.72
37 INT63341 Negative_regulation of ICAM1 42 0.59 30.45 9.5 97.52
38 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 97.38
39 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 97.24
40 INT48896 Positive_regulation of Gene_expression of Il10 73 0.70 43.14 35.5 97.24
41 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92 97.08
42 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 96.98
43 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 96.96
44 INT76713 Regulation of Gene_expression of PECAM1 16 0.40 14.52 2.51 96.96
45 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 96.64
46 INT63340 Positive_regulation of Gene_expression of ICAM1 109 0.70 90.82 20.61 96.64
47 INT27964 Negative_regulation of CBR1 12 0.58 5.48 3.74 96.60
48 INT17685 Negative_regulation of Cog1 23 0.42 15.65 3.56 96.32
49 INT17886 Negative_regulation of Il1 95 0.57 70.91 31.25 96.24
50 INT222884 Negative_regulation of Transcription of Il1 3 0.05 2.68 0.49 96.24
51 INT76095 Positive_regulation of ISYNA1 117 0.55 79.73 25.86 96.16
52 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 95.96
53 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68 95.84
54 INT79169 Binding of PLG 10 0.47 5.88 0.72 95.80
55 INT12082 Localization of IL6 365 0.81 241.78 105.78 95.76
56 INT59321 Transcription of Il1 13 0.50 9.73 2.68 95.72
57 INT1200 Negative_regulation of Ins1 274 0.58 155.17 56.14 95.60
58 INT351000 Binding of Adh7 1 0.01 3.4 0.03 95.60
59 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 95.40
60 INT54662 Positive_regulation of Positive_regulation of Il1 21 0.43 19.33 7.14 95.40
61 INT25610 Positive_regulation of Gene_expression of Il1 136 0.67 104.43 43.86 95.40
62 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 95.40
63 INT12104 Positive_regulation of PLG 45 0.68 28.94 4.81 95.00
64 INT27918 Positive_regulation of Klk1c7 6 0.36 2.89 2.84 95.00
65 INT4460 Regulation of Mpo 44 0.62 31.16 12.11 95.00
66 INT11335 Regulation of Ptger2 46 0.51 22.3 15.42 94.94
67 INT92822 Negative_regulation of Gene_expression of Crp 36 0.49 29.5 8.83 94.84
68 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 94.72
69 INT86437 Binding of IL6 154 0.48 121.22 29.3 94.56
70 INT192761 Positive_regulation of Gene_expression of SAA1 5 0.40 7.45 0.82 94.40
71 INT251894 Regulation of Regulation of Lama5 1 0.01 1.07 0.08 94.40
72 INT251895 Regulation of Lama5 1 0.01 1.06 0.08 94.40
73 INT25463 Negative_regulation of Gene_expression of MRXS5 7 0.38 4.75 2.12 94.12
74 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 93.72
75 INT10565 Gene_expression of MRXS5 94 0.53 37.35 19.08 93.72
76 INT63348 Regulation of PECAM1 14 0.40 16.05 0.97 93.64
77 INT43900 Gene_expression of RASA1 13 0.58 12 2.03 93.64
78 INT100548 Regulation of SELP 8 0.29 8.56 1.17 93.60
79 INT267147 Regulation of Positive_regulation of SELP 2 0.29 3.94 0.42 93.60
80 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 93.52
81 INT1764 Negative_regulation of Gene_expression of PTGER2 81 0.34 34.74 19.45 93.48
82 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 93.28
83 INT20102 Gene_expression of Serpine1 102 0.78 65.99 12.61 93.12
84 INT128061 Negative_regulation of Gene_expression of Serpine1 16 0.43 13.13 1.29 93.12
85 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 93.04
86 INT65016 Gene_expression of SOS1 4 0.61 0.47 0.65 92.96
87 INT27962 Gene_expression of CBR1 2 0.59 1.27 0.57 92.96
88 INT27963 Negative_regulation of Gene_expression of CBR1 2 0.42 1.28 0.57 92.96
89 INT6481 Binding of TNF 624 0.48 510.2 214.82 92.84
90 INT12892 Negative_regulation of TIMP1 136 0.58 83.13 36.54 92.60
91 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 92.32
92 INT211361 Regulation of RENBP 5 0.08 2.8 0.38 92.24
93 INT1765 Positive_regulation of Gene_expression of PTGER2 140 0.51 68.68 27 92.16
94 INT2429 Negative_regulation of Mpo 128 0.59 93.76 39.57 91.80
95 INT111335 Gene_expression of HSPD1 57 0.75 55.51 10.38 91.64
96 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 91.56
97 INT49801 Positive_regulation of SELP 21 0.48 21.34 5.25 91.28
98 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 91.28
99 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 91.08
100 INT8580 Gene_expression of ELANE 132 0.75 62.98 21.79 91.08
101 INT4391 Gene_expression of SERPINA1 47 0.78 41.43 9.7 91.08
102 INT10141 Gene_expression of A2M 11 0.35 9.37 2.75 91.08
103 INT10918 Gene_expression of ITGB2 93 0.76 71.8 16.34 90.56
104 INT10915 Gene_expression of ITGAM 164 0.78 92.42 29.78 90.28
105 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 90.12
106 INT135319 Positive_regulation of Positive_regulation of CRP 20 0.50 26.45 5.61 90.12
107 INT151115 Regulation of Regulation of Bcl2 4 0.21 4.12 0.88 89.96
108 INT145929 Regulation of Bax 20 0.60 18.12 5.35 89.96
109 INT258726 Positive_regulation of Nfxl1 1 0.05 1.89 0.18 89.88
110 INT87632 Positive_regulation of Gene_expression of PECAM1 32 0.45 29.47 4.66 89.80
111 INT230108 Localization of HIST4H4 2 0.40 1.07 0 89.76
112 INT120371 Gene_expression of FEZF2 12 0.66 4.97 1.38 89.60
113 INT184169 Positive_regulation of Gene_expression of FEZF2 2 0.17 2.8 0.26 89.60
114 INT129856 Positive_regulation of TNFRSF11A 26 0.68 16.21 4.75 89.40
115 INT130865 Positive_regulation of TNFSF11 29 0.69 12.82 2.99 89.40
116 INT72127 Protein_catabolism of MMRN1 68 0.52 56 14.13 89.20
117 INT251896 Negative_regulation of Lama5 1 0.01 0.82 0.03 89.08
118 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 89.04
119 INT81140 Gene_expression of CYTIP 5 0.65 1.76 0.12 88.96
120 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24 88.96
121 INT65019 Regulation of SOS1 2 0.56 0.42 0.49 88.80
122 INT62826 Negative_regulation of Gene_expression of ICAM1 75 0.58 46.39 17.72 88.56
123 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 88.48
124 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41 88.36
125 INT64185 Gene_expression of TNFRSF11A 131 0.76 75.15 24.73 88.28
126 INT35146 Negative_regulation of PLG 27 0.57 17.63 1.98 88.00
127 INT156850 Binding of VDR 40 0.47 24.86 4.87 87.92
128 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 87.56
129 INT215358 Negative_regulation of HSPE1 1 0.56 0.65 0.17 87.48
130 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 87.16
131 INT108588 Gene_expression of CASP3 126 0.78 84.49 16.2 86.96
132 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 86.92
133 INT71374 Positive_regulation of Gene_expression of Il12a 5 0.22 7.49 3.8 86.80
134 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 86.80
135 INT318710 Positive_regulation of Gene_expression of Sept3 2 0.25 3.24 0.71 86.80
136 INT219610 Protein_catabolism of SAA1 2 0.90 4.47 0.54 86.76
137 INT2609 Localization of ELANE 111 0.81 50.22 26.63 86.76
138 INT150395 Binding of MEFV 55 0.44 31.18 3.42 86.68
139 INT48235 Negative_regulation of NPEPPS 72 0.46 44.54 25.03 86.36
140 INT2774 Binding of Crp 241 0.48 195.89 44.39 86.24
141 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 86.20
142 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 86.20
143 INT215373 Negative_regulation of Gene_expression of HSPE1 1 0.56 0.56 0.14 86.08
144 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72 86.04
145 INT19775 Localization of Il1 183 0.78 145.5 50.91 85.92
146 INT38056 Localization of Crp 71 0.78 53.14 17.03 85.92
147 INT11937 Localization of Il6 228 0.81 139.83 64.39 85.92
148 INT132853 Gene_expression of GCFC2 2 0.58 1.06 0.41 85.20
149 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03 85.12
150 INT24670 Gene_expression of FGF2 121 0.78 85.64 15.12 84.92
151 INT19432 Positive_regulation of Gene_expression of CD79A 14 0.45 13.49 1.49 84.64
152 INT27551 Gene_expression of SERPINH1 45 0.62 42.87 9.04 84.60
153 INT140906 Negative_regulation of Gene_expression of Il12a 4 0.38 5.28 1.86 84.36
154 INT80549 Binding of ICAM1 53 0.47 42.76 9.72 84.36
155 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 84.36
156 INT318711 Negative_regulation of Gene_expression of Sept3 1 0.14 1.31 0.35 84.36
157 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52 84.32
158 INT92311 Regulation of SIL1 7 0.44 6.2 1.61 84.08
159 INT260603 Regulation of SH3RF3 1 0.07 0.28 0 84.08
160 INT9660 Regulation of TNF 363 0.62 312.94 139.99 83.96
161 INT67401 Gene_expression of Il12a 25 0.55 20.04 11.12 83.92
162 INT318712 Gene_expression of Sept3 2 0.34 2.2 0.35 83.92
163 INT71769 Negative_regulation of Gene_expression of Il10 40 0.57 22.53 10.37 83.76
164 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 83.76
165 INT354920 Negative_regulation of Positive_regulation of VDR 1 0.21 1.96 0.04 83.76
166 INT56985 Gene_expression of MEFV 56 0.71 46.71 9.47 83.72
167 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 83.64
168 INT56809 Binding of Tlr4 184 0.48 106.02 31.18 83.60
169 INT219657 Regulation of H2BFS 3 0.06 0.83 0 83.52
170 INT72060 Positive_regulation of Gene_expression of Ros1 127 0.41 76.76 20.91 83.36
171 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 83.32
172 INT192970 Negative_regulation of Hp 7 0.22 6.99 4.06 83.12
173 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 83.00
174 INT65017 Negative_regulation of Gene_expression of SOS1 1 0.39 0.16 0.23 82.72
175 INT85877 Positive_regulation of Il12a 6 0.43 4.87 2.11 82.68
176 INT318709 Positive_regulation of Sept3 1 0.12 1.28 0.35 82.68
177 INT215363 Regulation of HSPD1 4 0.51 2.74 0.99 82.40
178 INT215368 Regulation of Positive_regulation of HSPD1 1 0.38 0.51 0.09 82.40
179 INT215364 Regulation of Gene_expression of HSPE1 1 0.26 0.51 0.09 82.40
180 INT215370 Regulation of Positive_regulation of HSPE1 1 0.43 0.51 0.09 82.40
181 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26 82.04
182 INT81575 Gene_expression of SIL1 29 0.25 19.76 1.24 81.96
183 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 81.92
184 INT215371 Positive_regulation of HSPE1 1 0.66 3.4 0.95 81.56
185 INT27880 Positive_regulation of HSPD1 17 0.65 18.16 2.23 81.56
186 INT81574 Positive_regulation of SIL1 21 0.67 10.85 0.31 81.56
187 INT89519 Negative_regulation of COL1A2 10 0.36 6.26 2.17 81.52
188 INT60475 Gene_expression of Ugt1a1 17 0.77 4.26 5.62 81.44
189 INT104744 Negative_regulation of Gene_expression of Ugt1a1 2 0.53 0.85 0 81.44
190 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62 81.36
191 INT9210 Regulation of IL6 166 0.62 125.61 49.95 81.32
192 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28 81.28
193 INT78816 Positive_regulation of Positive_regulation of ICAM1 9 0.68 8.36 1.55 81.28
194 INT139237 Negative_regulation of Gene_expression of CDH1 23 0.57 24.31 1.28 80.92
195 INT72565 Localization of IL1RN 45 0.80 23.59 13.17 80.40
196 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 80.24
197 INT135181 Regulation of Gene_expression of TNFSF11 5 0.61 6.98 1.27 79.84
198 INT62400 Positive_regulation of Localization of Il1 34 0.67 35.53 7.96 79.68
199 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 79.48
200 INT80784 Regulation of BCS1L 9 0.39 7.63 1.47 79.16
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