D:Periodontal Pocket

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pChart

Disease Term
Synonyms Periodontal Pockets, Pocket Periodontal, Pockets Periodontal
Documents 99
Hot Single Events 19
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Periodontal Pocket. They are ordered first by their relevance to Periodontal Pocket and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT128644 Binding of Icam1 and Selp 2 0.39 0.57 0.25 5.00
2 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17 5.00
3 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15 5.00
4 INT329342 Binding of THAS and LRRFIP1 1 0.00 0.97 0.09 5.00
5 INT329340 UCN2 Positive_regulation of SOD1 1 0.02 1.12 0 5.00
6 INT329341 UCN2 Positive_regulation of THAS 1 0.00 1.12 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Periodontal Pocket. They are ordered first by their pain relevance and then by number of times they were reported in Periodontal Pocket. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT172924 Gene_expression of BOP 8 0.47 3.15 0.14 99.20
2 INT116605 Binding of Nos2 28 0.37 16.88 8.18 98.00
3 INT215360 Binding of HSPE1 1 0.36 3.63 0.92 95.92
4 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52 95.56
5 INT97474 Positive_regulation of UCN2 6 0.67 1.85 1.23 94.52
6 INT234362 Localization of NR3C2 2 0.27 0.15 0 92.96
7 INT17227 Gene_expression of 16S 11 0.75 2.65 0.76 92.28
8 INT52546 Gene_expression of NR3C2 10 0.65 1.09 1.1 92.12
9 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 88.52
10 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 88.52
11 INT215372 Positive_regulation of Binding of HSPE1 1 0.48 0.27 0 87.44
12 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 84.72
13 INT2116 Negative_regulation of VSX1 29 0.36 10.67 1.89 84.16
14 INT53189 Gene_expression of VSX1 32 0.69 10.59 7.21 84.16
15 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 80.76
16 INT8580 Gene_expression of ELANE 132 0.75 62.98 21.79 80.76
17 INT4391 Gene_expression of SERPINA1 47 0.78 41.43 9.7 80.76
18 INT10141 Gene_expression of A2M 11 0.35 9.37 2.75 80.76
19 INT18773 Localization of ALB 117 0.80 69.18 13.8 80.04
20 INT57720 Localization of IGHG3 33 0.74 20.24 6.25 79.68
21 INT215371 Positive_regulation of HSPE1 1 0.66 3.4 0.95 79.56
22 INT215367 Positive_regulation of Positive_regulation of HSPE1 1 0.48 0.57 0 79.56
23 INT239411 Localization of APOB 10 0.76 5.71 0.04 79.32
24 INT12892 Negative_regulation of TIMP1 136 0.58 83.13 36.54 76.80
25 INT355025 Positive_regulation of Binding of HPD 1 0.10 0.63 0 76.28
26 INT296386 Localization of DEFA6 3 0.05 0.88 0 75.40
27 INT269716 Binding of HPD 3 0.31 1.42 0.08 75.20
28 INT251896 Negative_regulation of Lama5 1 0.01 0.82 0.03 75.20
29 INT335830 Gene_expression of LRRFIP1 1 0.22 2.43 0.38 74.00
30 INT297033 Localization of ATP6V0A1 2 0.50 1.07 0.04 73.76
31 INT92822 Negative_regulation of Gene_expression of Crp 36 0.49 29.5 8.83 72.12
32 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 71.80
33 INT150276 Positive_regulation of LRRFIP1 2 0.37 1.34 0.03 67.12
34 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 65.24
35 INT278596 Localization of BOP 1 0.45 1.15 0.24 63.60
36 INT192970 Negative_regulation of Hp 7 0.22 6.99 4.06 62.52
37 INT191739 Positive_regulation of 16S 6 0.49 0.76 0.04 62.48
38 INT17228 Regulation of 16S 8 0.60 0.84 0.21 61.36
39 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4 60.64
40 INT215362 Positive_regulation of Gene_expression of HSPE1 1 0.44 1.82 0.71 58.00
41 INT215366 Gene_expression of HSPE1 12 0.74 6.39 1.39 58.00
42 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 57.12
43 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 56.28
44 INT1200 Negative_regulation of Ins1 274 0.58 155.17 56.14 54.44
45 INT81575 Gene_expression of SIL1 29 0.25 19.76 1.24 47.12
46 INT92311 Regulation of SIL1 7 0.44 6.2 1.61 45.08
47 INT215363 Regulation of HSPD1 4 0.51 2.74 0.99 45.08
48 INT215359 Regulation of Gene_expression of SIL1 2 0.14 1.11 0.37 45.08
49 INT111335 Gene_expression of HSPD1 57 0.75 55.51 10.38 44.48
50 INT178547 Gene_expression of CSTB 9 0.29 6.53 0.18 39.68
51 INT151095 Gene_expression of ATP6V0A1 13 0.48 4.4 1.37 38.76
52 INT17685 Negative_regulation of Cog1 23 0.42 15.65 3.56 38.24
53 INT72060 Positive_regulation of Gene_expression of Ros1 127 0.41 76.76 20.91 37.72
54 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 37.36
55 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 36.00
56 INT27881 Binding of HSPD1 10 0.31 9.2 1.78 35.60
57 INT215365 Gene_expression of SCAP 4 0.01 1.93 0.19 33.92
58 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 27.04
59 INT215361 Regulation of HSPE1 1 0.43 1.4 0.34 24.40
60 INT142732 Negative_regulation of STATH 3 0.42 1.72 0.16 23.52
61 INT158540 Negative_regulation of HTN1 4 0.34 7.25 1.22 22.40
62 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 21.76
63 INT9655 Regulation of Il6 98 0.62 70.92 31.95 18.28
64 INT174687 Regulation of Positive_regulation of Il6 10 0.61 9.07 2.61 18.28
65 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 14.56
66 INT278595 Regulation of Binding of BOP 1 0.27 0.33 0.05 9.76
67 INT251894 Regulation of Regulation of Lama5 1 0.01 1.07 0.08 8.64
68 INT251895 Regulation of Lama5 1 0.01 1.06 0.08 8.64
69 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
70 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
71 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 5.00
72 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 5.00
73 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 5.00
74 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
75 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 5.00
76 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73 5.00
77 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 5.00
78 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 5.00
79 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 5.00
80 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
81 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
82 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
83 INT65500 Gene_expression of App 605 0.78 429.94 98.31 5.00
84 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 5.00
85 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 5.00
86 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 5.00
87 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47 5.00
88 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 5.00
89 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 5.00
90 INT11937 Localization of Il6 228 0.81 139.83 64.39 5.00
91 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 5.00
92 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 5.00
93 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 5.00
94 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67 5.00
95 INT19775 Localization of Il1 183 0.78 145.5 50.91 5.00
96 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 5.00
97 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 5.00
98 INT25610 Positive_regulation of Gene_expression of Il1 136 0.67 104.43 43.86 5.00
99 INT2429 Negative_regulation of Mpo 128 0.59 93.76 39.57 5.00
100 INT47939 Gene_expression of Selp 171 0.76 87.54 39.03 5.00
101 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94 5.00
102 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 5.00
103 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55 5.00
104 INT51017 Positive_regulation of Icam1 113 0.70 81.16 35.55 5.00
105 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89 5.00
106 INT81530 Gene_expression of Nfkb1 93 0.78 48.58 32.58 5.00
107 INT17886 Negative_regulation of Il1 95 0.57 70.91 31.25 5.00
108 INT56809 Binding of Tlr4 184 0.48 106.02 31.18 5.00
109 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72 5.00
110 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26 5.00
111 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
112 INT65537 Positive_regulation of Positive_regulation of Nfkb1 52 0.67 30.6 26.35 5.00
113 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62 5.00
114 INT68758 Positive_regulation of Ros1 125 0.46 82.72 25.27 5.00
115 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48 5.00
116 INT70503 Regulation of Gene_expression of Nos2 71 0.62 44 24.01 5.00
117 INT134651 Binding of TLR4 89 0.48 66.96 23.19 5.00
118 INT5905 Negative_regulation of ELANE 113 0.59 47.43 22.09 5.00
119 INT78057 Localization of Tlr4 140 0.77 67.75 21.72 5.00
120 INT52693 Positive_regulation of Gene_expression of Ptgs2 57 0.70 25.51 21.18 5.00
121 INT11625 Localization of App 98 0.78 55.46 20.86 5.00
122 INT65502 Regulation of App 77 0.62 52.05 19.44 5.00
123 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46 5.00
124 INT61519 Gene_expression of Mpo 112 0.78 89.29 18.22 5.00
125 INT38056 Localization of Crp 71 0.78 53.14 17.03 5.00
126 INT71510 Positive_regulation of Selp 47 0.68 30.43 12.8 5.00
127 INT55343 Localization of Ros1 39 0.60 34.51 12.5 5.00
128 INT12135 Gene_expression of PLEK 62 0.75 34.13 12.47 5.00
129 INT112003 Localization of ROS1 94 0.73 66.32 12.16 5.00
130 INT4460 Regulation of Mpo 44 0.62 31.16 12.11 5.00
131 INT81531 Positive_regulation of Gene_expression of Nfkb1 27 0.69 13.9 11.04 5.00
132 INT95632 Positive_regulation of MMP8 26 0.70 10.06 9.96 5.00
133 INT125247 Negative_regulation of Mmp9 42 0.43 23.68 9.37 5.00
134 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28 5.00
135 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 5.00
136 INT860 Regulation of ALB 48 0.60 25.11 8.95 5.00
137 INT55342 Negative_regulation of Gene_expression of Ros1 49 0.37 31.62 8.93 5.00
138 INT62400 Positive_regulation of Localization of Il1 34 0.67 35.53 7.96 5.00
139 INT62944 Regulation of Icam1 33 0.47 23.52 7.94 5.00
140 INT72219 Gene_expression of METTL3 45 0.24 9.58 7.61 5.00
141 INT81537 Regulation of Gene_expression of Nfkb1 10 0.57 7.09 7.48 5.00
142 INT70252 Gene_expression of Ugt1a6 20 0.77 3.89 7.45 5.00
143 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41 5.00
144 INT4228 Gene_expression of CAT 50 0.75 20.62 7.18 5.00
145 INT1950 Positive_regulation of Positive_regulation of Tlr4 38 0.49 20.17 7.14 5.00
146 INT54662 Positive_regulation of Positive_regulation of Il1 21 0.43 19.33 7.14 5.00
147 INT1124 Negative_regulation of CD40LG 53 0.57 36.26 7 5.00
148 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91 5.00
149 INT182351 Positive_regulation of Gene_expression of Apoe 38 0.50 19.78 6.72 5.00
150 INT116420 Localization of Elane 16 0.14 7.8 6 5.00
151 INT1126 Negative_regulation of CD79A 46 0.59 31.07 6 5.00
152 INT141751 Localization of Syt1 21 0.78 11.19 5.98 5.00
153 INT91159 Negative_regulation of Ros1 35 0.44 26.12 5.97 5.00
154 INT63177 Regulation of HP 71 0.44 39.48 5.86 5.00
155 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7 5.00
156 INT60475 Gene_expression of Ugt1a1 17 0.77 4.26 5.62 5.00
157 INT87468 Negative_regulation of Mmp2 24 0.57 10.79 5.55 5.00
158 INT145929 Regulation of Bax 20 0.60 18.12 5.35 5.00
159 INT144946 Localization of Icam1 21 0.75 21.84 5.33 5.00
160 INT141750 Positive_regulation of Localization of Syt1 10 0.67 5.53 5.28 5.00
161 INT73608 Localization of Nos2 21 0.75 9.58 5.05 5.00
162 INT131692 Negative_regulation of Localization of App 9 0.53 4.69 4.82 5.00
163 INT12104 Positive_regulation of PLG 45 0.68 28.94 4.81 5.00
164 INT57274 Positive_regulation of Gene_expression of COL7A1 50 0.69 24.19 4.72 5.00
165 INT1753 Gene_expression of Ache 38 0.78 15.31 4.58 5.00
166 INT25634 Binding of Mpo 21 0.48 14.78 4.39 5.00
167 INT125896 Negative_regulation of Gene_expression of Mmp9 15 0.43 13.73 4.18 5.00
168 INT106274 Positive_regulation of Syt1 16 0.67 9.76 4.1 5.00
169 INT22578 Gene_expression of Syt1 43 0.77 11.02 3.66 5.00
170 INT52678 Positive_regulation of VSX1 15 0.42 3.94 3.64 5.00
171 INT73802 Regulation of Selp 17 0.60 8.72 3.51 5.00
172 INT76501 Binding of Selp 16 0.41 8.51 3.4 5.00
173 INT2117 Regulation of VSX1 15 0.30 3.38 3.38 5.00
174 INT126223 Binding of Nos2 17 0.37 6 3.22 5.00
175 INT70994 Negative_regulation of Positive_regulation of Icam1 8 0.51 3.49 3.12 5.00
176 INT9884 Localization of CD79A 41 0.78 21.75 3.06 5.00
177 INT27918 Positive_regulation of Klk1c7 6 0.36 2.89 2.84 5.00
178 INT28891 Localization of Selp 13 0.60 8.23 2.83 5.00
179 INT104474 Gene_expression of Mmp8 15 0.71 3.1 2.76 5.00
180 INT171117 Binding of Itgam 35 0.36 14.87 2.76 5.00
181 INT74216 Binding of Icam1 16 0.48 10.11 2.69 5.00
182 INT59321 Transcription of Il1 13 0.50 9.73 2.68 5.00
183 INT185407 Binding of PER1 13 0.42 9.32 2.6 5.00
184 INT107894 Gene_expression of Nfkbib 5 0.75 1.14 2.55 5.00
185 INT31989 Binding of SOD1 43 0.47 19.38 2.55 5.00
186 INT27880 Positive_regulation of HSPD1 17 0.65 18.16 2.23 5.00
187 INT156093 Negative_regulation of Positive_regulation of Ros1 8 0.23 5.17 2.03 5.00
188 INT35146 Negative_regulation of PLG 27 0.57 17.63 1.98 5.00
189 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87 5.00
190 INT94163 Negative_regulation of UCN2 11 0.57 6.86 1.75 5.00
191 INT47615 Negative_regulation of DNASE1 9 0.58 3.62 1.74 5.00
192 INT57207 Protein_catabolism of Mpo 9 1.00 3.89 1.7 5.00
193 INT53188 Regulation of Gene_expression of VSX1 4 0.40 1.41 1.66 5.00
194 INT33393 Positive_regulation of Gene_expression of PLEK 9 0.67 7.35 1.65 5.00
195 INT74586 Negative_regulation of MMP8 6 0.27 1.68 1.64 5.00
196 INT27293 Regulation of SOD1 21 0.53 15.73 1.55 5.00
197 INT60571 Positive_regulation of Gsta4 8 0.45 3.76 1.44 5.00
198 INT120371 Gene_expression of FEZF2 12 0.66 4.97 1.38 5.00
199 INT80086 Regulation of Gene_expression of PLEK 5 0.60 2.79 1.29 5.00
200 INT131395 Positive_regulation of Gene_expression of Ugt1a6 6 0.69 1.86 1.23 5.00
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