D:Periostitis

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pChart

Disease Term
Synonyms PERIOSTITIDES
Documents 136
Hot Single Events 16
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Periostitis. They are ordered first by their relevance to Periostitis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT317832 Binding of Mefv and Il1 1 0.03 3.89 0.7 79.60
2 INT317834 Binding of Pstpip1 and Il1 1 0.00 2.03 0.48 79.60
3 INT278379 Binding of Pstpip1 and Mefv 3 0.03 2.02 0.48 78.08
4 INT244656 Binding of S100B and SLC4A1 1 0.14 1.72 0.03 38.48
5 INT317833 Nlrp3 Positive_regulation of Localization of Il1 1 0.06 1.38 0.26 19.84
6 INT317836 Binding of Fibp and Pycard 1 0.00 2.68 0.98 5.00
7 INT150393 Binding of CASP1 and MEFV 2 0.16 2.48 0.45 5.00
8 INT317835 Nlrp3 Positive_regulation of Il18 1 0.08 1.49 0.31 5.00
9 INT334879 CASP1 Regulation of IL1B 1 0.03 1.63 0.31 5.00
10 INT317831 Binding of Mefv and Nlrx1 1 0.00 1.77 0.2 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Periostitis. They are ordered first by their pain relevance and then by number of times they were reported in Periostitis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT161035 Positive_regulation of Mtss1 2 0.58 1.99 0.48 99.84
2 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 99.04
3 INT108798 Negative_regulation of Positive_regulation of ALPP 9 0.25 4.26 1.46 98.72
4 INT20129 Regulation of Il1 53 0.53 44.14 19.89 96.28
5 INT129856 Positive_regulation of TNFRSF11A 26 0.68 16.21 4.75 95.82
6 INT93533 Positive_regulation of Tnfsf11 53 0.50 36.93 10.53 95.82
7 INT141896 Positive_regulation of SQSTM1 6 0.50 5.58 0.26 95.82
8 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 94.48
9 INT105702 Binding of Mkl1 1 0.31 1.06 0 91.00
10 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 90.00
11 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 88.32
12 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 86.32
13 INT19775 Localization of Il1 183 0.78 145.5 50.91 86.32
14 INT62400 Positive_regulation of Localization of Il1 34 0.67 35.53 7.96 86.32
15 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 84.32
16 INT2673 Negative_regulation of PROC 93 0.57 50.34 12.79 81.28
17 INT59900 Binding of MATN3 13 0.42 17.19 3.59 76.48
18 INT4535 Localization of PROC 106 0.73 76.24 21.1 73.12
19 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 72.72
20 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 71.20
21 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59 70.68
22 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5 70.68
23 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 68.88
24 INT9292 Positive_regulation of SGCG 93 0.67 35.13 23.48 68.32
25 INT61171 Gene_expression of S100A8 92 0.76 57.74 9.98 61.52
26 INT94042 Positive_regulation of Gene_expression of S100A8 15 0.67 13.52 2.44 61.52
27 INT72455 Transcription of S100A8 3 0.69 1.66 0.36 61.52
28 INT334889 Positive_regulation of Transcription of MRPL14 1 0.07 0.79 0.21 61.52
29 INT334883 Positive_regulation of Transcription of CBFA2T2 1 0.03 0.79 0.21 61.52
30 INT334884 Transcription of CBFA2T2 1 0.04 0.78 0.21 61.52
31 INT334887 Positive_regulation of Gene_expression of CBFA2T2 1 0.03 0.79 0.21 61.52
32 INT334888 Gene_expression of CBFA2T2 1 0.05 0.78 0.21 61.52
33 INT334885 Transcription of MRPL14 1 0.10 0.79 0.21 61.52
34 INT334886 Gene_expression of MRPL14 1 0.11 0.79 0.21 61.52
35 INT334890 Positive_regulation of Gene_expression of MRPL14 1 0.07 0.79 0.21 61.52
36 INT334891 Positive_regulation of Transcription of S100A8 1 0.06 0.79 0.21 61.52
37 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 54.72
38 INT59899 Regulation of MATN3 4 0.45 7.61 1.6 52.96
39 INT33562 Negative_regulation of Mtss1 2 0.36 0.61 1.2 51.12
40 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 44.40
41 INT25607 Binding of Il1 82 0.47 64.4 23.9 41.00
42 INT219136 Positive_regulation of Positive_regulation of Nlrp3 3 0.49 2.61 0.58 25.04
43 INT36221 Positive_regulation of Nlrp3 25 0.68 19.7 4.5 21.24
44 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 20.32
45 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 18.48
46 INT284359 Negative_regulation of Mvk 4 0.37 6.62 0.99 16.08
47 INT317823 Positive_regulation of Negative_regulation of Mvk 2 0.30 3.33 0.62 16.08
48 INT284362 Positive_regulation of Mvk 3 0.44 3.32 0.46 16.08
49 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
50 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
51 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
52 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
53 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
54 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 5.00
55 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 5.00
56 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37 5.00
57 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 5.00
58 INT22454 Regulation of Crp 213 0.62 160.67 49.24 5.00
59 INT117598 Regulation of ACR 118 0.26 41.25 48.01 5.00
60 INT2774 Binding of Crp 241 0.48 195.89 44.39 5.00
61 INT173693 Localization of Gopc 249 0.65 70.49 38.81 5.00
62 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28 5.00
63 INT6484 Binding of IL1B 122 0.47 75.84 35.07 5.00
64 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4 5.00
65 INT132161 Gene_expression of MTX1 48 0.58 26.55 32.32 5.00
66 INT17886 Negative_regulation of Il1 95 0.57 70.91 31.25 5.00
67 INT56809 Binding of Tlr4 184 0.48 106.02 31.18 5.00
68 INT58288 Positive_regulation of Gene_expression of Crp 83 0.61 82.23 23.7 5.00
69 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92 5.00
70 INT63340 Positive_regulation of Gene_expression of ICAM1 109 0.70 90.82 20.61 5.00
71 INT89484 Gene_expression of TNFRSF11B 119 0.76 53.57 19.67 5.00
72 INT38056 Localization of Crp 71 0.78 53.14 17.03 5.00
73 INT73829 Positive_regulation of Gene_expression of VCAM1 41 0.61 35.96 11.92 5.00
74 INT69035 Positive_regulation of Casp1 43 0.69 25.18 10.67 5.00
75 INT25608 Regulation of Gene_expression of Il1 37 0.44 27.76 10.1 5.00
76 INT27551 Gene_expression of SERPINH1 45 0.62 42.87 9.04 5.00
77 INT158796 Positive_regulation of SMUG1 67 0.70 38.97 8.98 5.00
78 INT92822 Negative_regulation of Gene_expression of Crp 36 0.49 29.5 8.83 5.00
79 INT621 Positive_regulation of SERPINH1 19 0.57 21.52 8.44 5.00
80 INT14043 Binding of HP 52 0.30 26.56 7.76 5.00
81 INT102251 Positive_regulation of Positive_regulation of Crp 24 0.58 29.62 7.5 5.00
82 INT54662 Positive_regulation of Positive_regulation of Il1 21 0.43 19.33 7.14 5.00
83 INT13406 Negative_regulation of CASP1 25 0.57 10.61 6.36 5.00
84 INT90077 Gene_expression of Casp1 29 0.76 20.79 6.26 5.00
85 INT114180 Negative_regulation of Il1rn 22 0.57 11.06 5.44 5.00
86 INT174688 Binding of Tlr2 45 0.42 36.65 5.25 5.00
87 INT62822 Positive_regulation of Gene_expression of SELE 22 0.66 28.04 4.97 5.00
88 INT209893 Positive_regulation of Gene_expression of TNFRSF11B 31 0.68 11.77 4.8 5.00
89 INT18011 Positive_regulation of HP 60 0.50 31.88 4.75 5.00
90 INT17110 Gene_expression of PSMD1 60 0.65 19.57 4.69 5.00
91 INT14470 Gene_expression of HCC 83 0.67 110.55 4.61 5.00
92 INT1901 Binding of Mefv 24 0.48 32.26 4.5 5.00
93 INT15982 Positive_regulation of NLRP3 25 0.65 23.19 3.57 5.00
94 INT52899 Positive_regulation of TNFRSF1A 16 0.46 19.04 3.34 5.00
95 INT16976 Negative_regulation of IL36RN 6 0.49 5.08 3.31 5.00
96 INT9089 Positive_regulation of Ceacam1 17 0.69 7.09 2.49 5.00
97 INT72782 Positive_regulation of HCC 41 0.40 63.74 2.46 5.00
98 INT33243 Localization of HP 17 0.12 9.7 2.2 5.00
99 INT149669 Positive_regulation of MEFV 12 0.46 14.17 2.07 5.00
100 INT211203 Positive_regulation of Gene_expression of IMPACT 1 0.17 2 1.75 5.00
101 INT211200 Regulation of SERPINH1 2 0.03 3.8 1.75 5.00
102 INT155130 Gene_expression of IMPACT 14 0.58 3.43 1.61 5.00
103 INT126759 Negative_regulation of Nlrp3 5 0.41 2.95 1.58 5.00
104 INT53236 Positive_regulation of Binding of Il1 5 0.40 3.84 1.41 5.00
105 INT96073 Localization of Casp1 11 0.78 4.91 1.29 5.00
106 INT211198 Localization of SERPINH1 2 0.66 4.33 1.25 5.00
107 INT209915 Protein_catabolism of Il1 6 0.57 3.97 1.17 5.00
108 INT209912 Gene_expression of Pycard 17 0.22 12.04 1.04 5.00
109 INT130233 Positive_regulation of Binding of Crp 5 0.49 2.54 1.01 5.00
110 INT157115 Positive_regulation of Localization of Crp 4 0.59 1.96 0.88 5.00
111 INT15783 Regulation of SMS 6 0.23 3.2 0.75 5.00
112 INT108308 Gene_expression of ENOX1 10 0.77 1.65 0.74 5.00
113 INT222205 Positive_regulation of PSTPIP1 8 0.69 4.69 0.62 5.00
114 INT168448 Localization of Nlrp3 5 0.73 3.75 0.58 5.00
115 INT274601 Regulation of PSTPIP1 3 0.45 3.76 0.28 5.00
116 INT298971 Positive_regulation of Localization of Casp1 2 0.06 0.97 0.28 5.00
117 INT317821 Regulation of Gene_expression of Casp1 1 0.05 1.74 0.24 5.00
118 INT236278 Negative_regulation of CADPS 4 0.36 2.16 0.22 5.00
119 INT183473 Negative_regulation of SMS 3 0.35 2.14 0.2 5.00
120 INT142816 Negative_regulation of ENOX1 4 0.04 0.22 0.17 5.00
121 INT304192 Negative_regulation of SNRPD1 2 0.15 1.44 0.14 5.00
122 INT304201 Gene_expression of SNRPD1 2 0.22 1.12 0.09 5.00
123 INT304200 Positive_regulation of SNRPD1 2 0.18 0.67 0.04 5.00
124 INT196313 Gene_expression of sty 1 0.05 0.26 0 5.00
125 INT79726 Binding of Spef1 2 0.05 0.44 0 5.00
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