D:Peripheral Neuropathy

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pChart

Disease Term
Synonyms Charcot Marie Tooth, COWCHOCK SYNDROME, FAMILIAL MOTOR SENSOR NEUROPATHY, Fredreich S Ataxia, HEREDITARY MOTOR SENSOR NEUROPATHY, Nerve Disease Peripheral, Nerve Diseases Peripheral, Neuropathy Peripheral, Peripheral Nerve Disease, PERIPHERAL NERVE DISEASES, Peripheral Nervous System Disease
Documents 2325
Hot Single Events 200
Hot Interactions 16

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Peripheral Neuropathy. They are ordered first by their relevance to Peripheral Neuropathy and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT329409 Binding of SPTLC1 and Dstn 1 0.05 1.3 0.23 97.68
2 INT93701 Binding of TNF and TNFAIP2 1 0.02 0.97 0.11 96.28
3 INT102122 Binding of Calca and RT1-M4 7 0.29 5.83 4.94 93.48
4 INT110834 Binding of AGXT and SPTLC2 2 0.27 0.71 0.36 92.92
5 INT233303 Binding of CD4 and SRY 1 0.07 0.34 0.05 91.76
6 INT110835 Binding of SPTLC2 and SPTLC1 2 0.42 1.36 0.68 91.04
7 INT228454 Ngf Positive_regulation of Phosphorylation of Trpv1 1 0.39 2.97 2.26 89.04
8 INT348398 LPA Positive_regulation of Pik3cb 1 0.04 0.88 1.14 88.72
9 INT348400 LPA Positive_regulation of Trib3 1 0.00 0.87 1.14 88.72
10 INT330182 Binding of ITIH2 and BRD4 1 0.05 0.37 0.32 86.64
11 INT302676 Binding of OPA1 and MFN2 1 0.46 1.12 0.14 86.44
12 INT348403 FDPS Negative_regulation of FDPS Negative_regulation of Fdps 1 0.03 0.79 0.71 86.40
13 INT133854 Mcc Positive_regulation of Ngf 1 0.00 0.9 0.56 84.88
14 INT230760 VEGFA Positive_regulation of Flt1 1 0.03 0.96 0.12 84.16
15 INT230761 VEGFA Positive_regulation of Kdr 2 0.02 2.16 0.12 84.16
16 INT234831 Binding of SPTLC1 and Abo 1 0.00 1.61 0.23 82.64
17 INT262758 MRGPRF Positive_regulation of Transcription of NFE2L3 1 0.01 1.25 0.09 78.84
18 INT262754 MRGPRF Positive_regulation of NFE2L3 1 0.01 1.24 0.09 78.84
19 INT262755 MRGPRF Positive_regulation of NFE2L2 1 0.18 1.24 0.09 78.84
20 INT279962 Binding of A1BG and BCL2L1 1 0.13 1.11 0.1 77.88
21 INT221068 Cd79a Regulation of Gene_expression of IgG 1 0.01 0.93 0.1 75.32
22 INT221067 Cd79a Regulation of IgG 1 0.01 0.93 0.1 75.32
23 INT262760 Binding of TEP1 and CD163L1 1 0.00 1.65 0.37 75.20
24 INT221066 Cd79a Regulation of Gene_expression of Ighm 1 0.01 0.93 0.1 75.12
25 INT130469 Tubgcp2 Negative_regulation of Naalad2 1 0.05 0.44 0.5 75.00
26 INT212301 NGF Regulation of Gene_expression of TRPV1 1 0.23 2.37 2.13 74.08
27 INT149386 Binding of Lyn and TRPV4 1 0.40 1.14 0.91 73.64
28 INT314756 IL6 Positive_regulation of Gene_expression of Crp 2 0.13 4.58 0.48 72.00
29 INT332588 Binding of RAPH1 and MND1 1 0.01 3.88 0.07 71.96
30 INT256227 Binding of EDN1 and VEGFA 1 0.18 2.92 0.25 70.76
31 INT279965 STAT3 Regulation of Transcription of BCL2L1 1 0.10 2.31 0.19 70.24
32 INT120870 Binding of Wnk1 and Sptlc1 1 0.14 1.24 0.56 67.36
33 INT166625 Acer3 Positive_regulation of Trpa1 1 0.01 1.91 1 66.80
34 INT156799 Gria1 Regulation of Grm8 1 0.11 1.29 2.45 66.32
35 INT256042 Negative_regulation of Musk Negative_regulation of Ntrk1 1 0.08 0.48 0.44 62.88
36 INT19476 Binding of IL1A and Il6 1 0.00 2.19 0.36 58.16
37 INT19477 Binding of IL1A and Csf2 1 0.00 2.19 0.36 58.16
38 INT279964 STAT3 Regulation of Transcription of FGG 1 0.22 1.37 0.2 58.16
39 INT298873 RAB7A Regulation of Protein_catabolism of NTRK1 1 0.12 0.25 0.03 58.00
40 INT148541 ST3GAL4 Positive_regulation of Positive_regulation of Trpv1 1 0.08 0.96 0.56 57.96
41 INT234801 RAB3GAP1 Regulation of RAB3A 1 0.08 1.64 0.15 56.92
42 INT326571 Binding of Hsf1 and Hsp90ab1 1 0.16 1.19 0.03 52.88
43 INT326570 Hsp90ab1 Regulation of Csprs 1 0.08 1.17 0.03 52.88
44 INT298872 RAB7A Regulation of Protein_catabolism of GFM1 1 0.47 0.22 0.03 51.36
45 INT302883 Binding of TXN and Alb 1 0.06 4.13 0.1 51.04
46 INT263230 Prkcg Regulation of Trpv1 1 0.05 0.95 0.56 50.68
47 INT148542 ST3GAL4 Regulation of Gene_expression of Trpv1 1 0.05 0.97 0.51 50.28
48 INT285659 Binding of Faah and Mgll 1 0.15 0.99 1.11 47.84
49 INT166624 Acer3 Positive_regulation of Acer3 Positive_regulation of Trpa1 1 0.00 0.78 0.37 47.76
50 INT237460 Binding of TTPA and ADAMTS3 1 0.01 0.63 0 46.60
51 INT237461 Binding of UTS2R and TTPA 1 0.01 0.63 0 46.40
52 INT263232 Prkcg Positive_regulation of Trpv4 1 0.12 1.1 1.02 46.16
53 INT210878 Binding of FLT1 and HBM 1 0.06 0.83 0.5 41.92
54 INT328981 Binding of Mup1 and Cts 1 0.14 1.05 0.88 41.84
55 INT262558 Phax Positive_regulation of Trpv1 1 0.01 1.26 1.92 38.00
56 INT281126 Binding of Ccr2 and Cxcr4 1 0.30 0.32 0.44 37.08
57 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 34.00
58 INT177958 IGHE Positive_regulation of TNF 1 0.03 2.23 0 33.92
59 INT177959 Positive_regulation of IGHE Positive_regulation of TNF 1 0.03 2.23 0 33.92
60 INT312841 Pou3f1 Regulation of Gene_expression of Plp1 1 0.24 0.16 0.09 32.08
61 INT312843 Egr2 Regulation of Gene_expression of Plp1 1 0.31 0.16 0.09 32.08
62 INT121226 Ngf Regulation of Gene_expression of Trpv1 2 0.62 0.7 1.44 31.52
63 INT312840 Egr2 Regulation of Gene_expression of Mag 1 0.31 0.16 0.09 31.44
64 INT312842 Pou3f1 Regulation of Gene_expression of Mag 1 0.24 0.16 0.09 31.44
65 INT312839 Egr2 Regulation of Gene_expression of Mbp 1 0.32 0.16 0.09 31.04
66 INT312845 Pou3f1 Regulation of Gene_expression of Mbp 1 0.25 0.16 0.09 31.04
67 INT312844 Pou3f1 Regulation of Gene_expression of Pmp22 1 0.27 0.16 0.09 30.64
68 INT312846 Egr2 Regulation of Gene_expression of Pmp22 1 0.35 0.16 0.09 30.64
69 INT262756 STAT3 Positive_regulation of NFE2L2 1 0.31 1.55 0 30.08
70 INT355687 Art2b Positive_regulation of Gene_expression of Mc3r 1 0.02 1.01 0.48 30.00
71 INT191984 Ide Positive_regulation of Nppc 1 0.04 0.13 0 27.76
72 INT332587 MND1 Positive_regulation of Binding of RAPH1 and MND1 1 0.00 2.21 0.03 23.44
73 INT262572 Ngf Positive_regulation of Mapk1 2 0.04 0.52 0.81 14.64
74 INT287480 Protein_catabolism of NFKBIB Positive_regulation of TBK1 1 0.01 0.6 0.03 13.12
75 INT238805 Binding of DSP and HSPB2 1 0.09 4.2 0.13 12.56
76 INT262564 Ngf Positive_regulation of Pik3r1 1 0.08 0.36 0.8 12.48
77 INT287479 PSMB10 Positive_regulation of TBK1 1 0.00 0.59 0.03 12.24
78 INT262579 Ngf Positive_regulation of Prkca 1 0.07 0.36 0.8 12.00
79 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39 10.00
80 INT322931 Binding of MOCS1 and Litaf 1 0.00 0.82 0 7.00
81 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36 5.00
82 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 5.00
83 INT73539 Binding of Ngf and Ngfr 5 0.45 3.99 4 5.00
84 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17 5.00
85 INT103548 Binding of TRPV1 and TRPV3 3 0.37 1.82 2.28 5.00
86 INT275398 Binding of ITIH4 and Htatsf1 1 0.02 5.05 2.24 5.00
87 INT140659 Phax Positive_regulation of Trpv1 3 0.49 0.68 2.18 5.00
88 INT97208 Binding of Gabrg1 and Gabbr1 2 0.07 0.31 1.94 5.00
89 INT93293 Ngf Regulation of Trpv1 2 0.28 0.71 1.9 5.00
90 INT349658 Nos2 Regulation of Gene_expression of Nos1 1 0.63 2.86 1.84 5.00
91 INT208991 Binding of CALM1 and Ca2 10 0.06 1.34 1.55 5.00
92 INT241750 Binding of CD4 and ITIH4 14 0.18 5.72 1.53 5.00
93 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38 5.00
94 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29 5.00
95 INT242623 Binding of Ntf3 and Ntrk3 5 0.22 1.31 1.29 5.00
96 INT262377 Binding of Comt and Fmod 1 0.06 1.47 1.29 5.00
97 INT348380 Binding of Fdps and Lpar5 1 0.07 1.45 1.25 5.00
98 INT256041 Binding of Ngfr and Ntrk1 3 0.14 0.9 1.13 5.00
99 INT296950 Tacr1 Negative_regulation of Gene_expression of Cck 1 0.30 0.94 1.11 5.00
100 INT214875 Ap3d1 Negative_regulation of Gene_expression of Fos 1 0.00 0.39 1.04 5.00
101 INT242642 Binding of BDNF and Ngfr 2 0.21 1.38 1.01 5.00
102 INT263227 Positive_regulation of Prkcg Regulation of Trpv4 1 0.07 0.95 1 5.00
103 INT275406 Binding of ITIH4 and Ccr5 1 0.09 2.88 0.97 5.00
104 INT275390 Binding of Ccr5 and Htatsf1 1 0.01 3.26 0.97 5.00
105 INT275409 Binding of ITIH4 and Cxcr4 1 0.09 2.87 0.97 5.00
106 INT275386 Binding of Cxcr4 and Htatsf1 1 0.01 3.25 0.97 5.00
107 INT222243 Negative_regulation of Binding of Trpv1 and Ccr5 1 0.21 0.57 0.86 5.00
108 INT222244 Binding of Trpv1 and Ccr5 1 0.19 0.57 0.86 5.00
109 INT285660 Cnrip1 Negative_regulation of Kcnk3 1 0.00 0.23 0.85 5.00
110 INT285656 Cnrip1 Negative_regulation of Kcnk3 1 0.00 0.23 0.85 5.00
111 INT140660 Phax Negative_regulation of Trpv1 2 0.08 0.58 0.84 5.00
112 INT256045 Binding of BDNF and Ntrk1 3 0.34 0.65 0.83 5.00
113 INT349657 Nos2 Regulation of Regulation of Nos1 1 0.24 0.9 0.8 5.00
114 INT328982 Binding of Igfals and Cts 1 0.05 0.92 0.8 5.00
115 INT281651 Phax Positive_regulation of Gene_expression of Trpv1 1 0.09 0.89 0.79 5.00
116 INT328976 Binding of Cst7 and Cts 1 0.08 0.92 0.79 5.00
117 INT262582 F2rl1 Regulation of Positive_regulation of Prkca 1 0.03 0.58 0.78 5.00
118 INT214876 Ap3d1 Negative_regulation of Gria1 1 0.00 0.4 0.78 5.00
119 INT328979 Binding of Muted and Cts 1 0.03 0.9 0.78 5.00
120 INT262562 F2rl1 Regulation of Trpv1 1 0.12 0.58 0.77 5.00
121 INT180496 Binding of CTS and PDXK 1 0.04 0.69 0.77 5.00
122 INT262563 Negative_regulation of Pax3 Regulation of Calca 1 0.01 0.75 0.76 5.00
123 INT262569 Pax3 Regulation of Calca 1 0.00 0.75 0.76 5.00
124 INT262577 Localization of Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.05 0.92 0.75 5.00
125 INT322128 Binding of Ca2 and Trpv4 1 0.03 1.1 0.75 5.00
126 INT262578 Prkaca Positive_regulation of Localization of Calca 1 0.03 0.71 0.75 5.00
127 INT328978 Binding of Igfals and Muted 1 0.02 0.85 0.73 5.00
128 INT328980 Binding of Cst7 and Igfals 1 0.06 0.85 0.73 5.00
129 INT328975 Binding of Igfals and Mup1 1 0.11 0.85 0.73 5.00
130 INT328983 Binding of Cst7 and Muted 1 0.04 0.84 0.73 5.00
131 INT328977 Binding of Cst7 and Mup1 1 0.18 0.84 0.73 5.00
132 INT262573 Par2 Regulation of Positive_regulation of Prkca 1 0.05 0.57 0.72 5.00
133 INT262580 Ngf Positive_regulation of Hspg2 1 0.03 0.35 0.72 5.00
134 INT262581 Prkca Positive_regulation of Phosphorylation of Trpv1 1 0.13 0.28 0.71 5.00
135 INT262574 Gnaq Positive_regulation of Prkca 1 0.00 0.57 0.71 5.00
136 INT328974 Binding of Muted and Mup1 1 0.06 0.83 0.71 5.00
137 INT262566 Par2 Regulation of Trpv1 1 0.20 0.57 0.71 5.00
138 INT262571 Phosphorylation of Trpv1 Positive_regulation of Localization of Calca 1 0.17 0.71 0.7 5.00
139 INT263236 DAG1 Positive_regulation of Prkcg 2 0.01 0.31 0.7 5.00
140 INT348396 Binding of LPAR5 and Fdps 1 0.07 0.81 0.69 5.00
141 INT209250 TRPV1 Positive_regulation of Localization of DRGX 1 0.06 0.82 0.68 5.00
142 INT262570 Binding of Pax3 and Trpv1 1 0.02 1.05 0.67 5.00
143 INT262576 Binding of Calca and Trpv1 1 0.13 1.05 0.66 5.00
144 INT88141 Hrh1 Positive_regulation of 1700061J05Rik 1 0.01 1.08 0.66 5.00
145 INT259776 Fbn2 Regulation of Negative_regulation of Agtr1a 1 0.00 1.42 0.66 5.00
146 INT88142 Pt Positive_regulation of 1700061J05Rik 1 0.04 1.08 0.66 5.00
147 INT222253 Binding of Cxcl10 and Fig4 1 0.09 0.66 0.65 5.00
148 INT348381 Fdps Positive_regulation of Lpar5 1 0.07 0.75 0.64 5.00
149 INT281130 Ccl2 Regulation of Gene_expression of Ccr2 1 0.04 1.09 0.64 5.00
150 INT348399 Fdps Positive_regulation of LPAR5 1 0.08 0.75 0.64 5.00
151 INT281134 Ccl2 Positive_regulation of Gene_expression of Ccr2 1 0.08 1.09 0.64 5.00
152 INT281122 Ccl2 Regulation of Ccr2 1 0.04 1.09 0.63 5.00
153 INT259768 Positive_regulation of Agtr1a Regulation of Etf1 1 0.00 1.32 0.62 5.00
154 INT281650 Trpv1 Positive_regulation of Localization of Calca 1 0.12 0.71 0.61 5.00
155 INT281132 Binding of Ccr3 and Cxcl10 1 0.00 0.25 0.6 5.00
156 INT252869 Binding of Trpv1 and Phax 2 0.01 0.18 0.6 5.00
157 INT281648 Negative_regulation of Binding of Trpv1 and Fig4 1 0.14 0.69 0.55 5.00
158 INT222252 Positive_regulation of Binding of Ccr2 and Fig4 1 0.16 0.67 0.55 5.00
159 INT222246 Binding of Ccr2 and Tcf21 1 0.29 0.67 0.55 5.00
160 INT263231 Positive_regulation of Trpv1 Positive_regulation of Prkcg 1 0.08 0.57 0.55 5.00
161 INT222249 Positive_regulation of Binding of Ccr2 and Tcf21 1 0.39 0.67 0.55 5.00
162 INT281647 Binding of Trpv1 and Fig4 1 0.12 0.68 0.55 5.00
163 INT222245 Binding of Ccr2 and Fig4 1 0.12 0.67 0.55 5.00
164 INT281124 Tcf21 Positive_regulation of Binding of Ddc 1 0.04 1.21 0.54 5.00
165 INT281129 Tcf21 Positive_regulation of Binding of Cd4 1 0.04 1.21 0.54 5.00
166 INT281649 Negative_regulation of Binding of Calca and Trpv1 1 0.13 0.67 0.54 5.00
167 INT281152 Tcf21 Positive_regulation of Binding of ITIH4 1 0.03 1.21 0.54 5.00
168 INT263229 Trpv1 Positive_regulation of Prkcg 1 0.08 0.57 0.54 5.00
169 INT281131 Tcf21 Positive_regulation of Rent1 1 0.00 1.19 0.53 5.00
170 INT275388 Binding of Lamp1 and Cxcr4 1 0.01 1.45 0.52 5.00
171 INT275403 Binding of Cxcr4 and GOLPH3 1 0.00 1.45 0.52 5.00
172 INT275387 Binding of Lamp1 and Ccr5 1 0.01 1.45 0.52 5.00
173 INT275405 Binding of GOLPH3 and Ccr5 1 0.00 1.46 0.52 5.00
174 INT262565 Prkaca Regulation of Negative_regulation of Trpv1 1 0.05 0.21 0.5 5.00
175 INT263228 Prkcg Regulation of Trpv4 1 0.07 0.36 0.5 5.00
176 INT330451 Ltbr Regulation of Trpv1 1 0.01 0.05 0.5 5.00
177 INT263235 Trpv4 Regulation of Trpv1 1 0.17 0.7 0.5 5.00
178 INT256040 Ngf Regulation of Gene_expression of Ntrk1 1 0.36 0.73 0.5 5.00
179 INT348402 LPA Positive_regulation of Gene_expression of Ptgs2 1 0.01 0.62 0.48 5.00
180 INT322131 Binding of Prkcg and Trpv4 1 0.04 0.75 0.46 5.00
181 INT275407 Binding of ERVW-1 and Ccr5 1 0.00 1.74 0.46 5.00
182 INT275399 Binding of ERVW-1 and Cxcr4 1 0.00 1.73 0.46 5.00
183 INT285661 Binding of Mgll and FAAH2 1 0.05 0.23 0.45 5.00
184 INT262575 Trpv1 Positive_regulation of Prkca 1 0.13 0.17 0.44 5.00
185 INT190097 Binding of Hivep3 and Hivep3 1 0.14 0.78 0.42 5.00
186 INT283714 Positive_regulation of Binding of Id2 and Homer1 1 0.08 1.34 0.42 5.00
187 INT283713 Binding of Id2 and Homer1 1 0.06 1.34 0.42 5.00
188 INT297229 Binding of Kcnj8 and Abcc8 1 0.03 0 0.42 5.00
189 INT275402 Trpv1 Regulation of Gene_expression of NDRG1 1 0.00 1.25 0.39 5.00
190 INT281154 ITIH4 Positive_regulation of Cxcr4 1 0.09 0.71 0.37 5.00
191 INT281123 Binding of Cd4 and Cxcr4 1 0.24 0.92 0.37 5.00
192 INT281128 Cd4 Positive_regulation of Cxcr4 1 0.25 0.71 0.37 5.00
193 INT265015 Pgr Positive_regulation of Sds 1 0.04 0.49 0.37 5.00
194 INT281155 Binding of ITIH4 and Ddc 1 0.09 1.27 0.37 5.00
195 INT281153 Binding of ITIH4 and Cd4 1 0.10 0.91 0.37 5.00
196 INT263226 Prkcg Negative_regulation of Positive_regulation of Ca2 1 0.01 0.58 0.36 5.00
197 INT329410 Binding of SPTLC1 and Spt 1 0.04 1 0.35 5.00
198 INT256043 Binding of Ngfr and Positive_regulation of Binding of Ngf Ntrk1 1 0.17 0.28 0.33 5.00
199 INT322129 Binding of Prkcg and Ca2 1 0.00 0.57 0.33 5.00
200 INT322133 Trpv4 Regulation of Ca2 1 0.04 0.16 0.33 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Peripheral Neuropathy. They are ordered first by their pain relevance and then by number of times they were reported in Peripheral Neuropathy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT244600 Negative_regulation of POSTN 5 0.18 3.12 1.64 100.00
2 INT345502 Positive_regulation of Binding of POSTN 1 0.07 0.93 0.62 100.00
3 INT321199 Binding of POSTN 2 0.31 1.94 0.62 100.00
4 INT17061 Positive_regulation of POSTN 12 0.42 5.33 2.28 100.00
5 INT90168 Regulation of Wnk1 2 0.04 0.63 0.29 100.00
6 INT90170 Regulation of HNB1 1 0.00 0.56 0.29 100.00
7 INT152629 Positive_regulation of Bid 6 0.46 6.74 1.78 99.98
8 INT156874 Positive_regulation of Gene_expression of S100a8 26 0.49 32.8 8.99 99.98
9 INT139169 Gene_expression of Pmp22 10 0.68 8.37 2.5 99.92
10 INT39712 Binding of pad 82 0.48 110.92 10.33 99.92
11 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 99.86
12 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1 99.86
13 INT15358 Transcription of Ngf 29 0.72 10.43 16.94 99.86
14 INT75225 Transcription of Ngfr 4 0.60 1.95 2.44 99.86
15 INT47680 Regulation of Gene_expression of Bdnf 92 0.62 41.61 53.24 99.86
16 INT16261 Transcription of Bdnf 101 0.72 49.41 40.64 99.86
17 INT47682 Transcription of Ntrk2 19 0.69 6.32 8.6 99.86
18 INT91065 Regulation of Transcription of Bdnf 13 0.62 12.48 6.13 99.86
19 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42 99.84
20 INT125190 Regulation of Gene_expression of Trpv1 38 0.62 32.57 23.2 99.84
21 INT10131 Gene_expression of Serpinf1 53 0.76 35.57 6.42 99.84
22 INT121161 Localization of Cx3cl1 14 0.75 10.07 10.61 99.84
23 INT4284 Regulation of Ddc 17 0.43 8.17 7.31 99.82
24 INT98621 Regulation of Trpv1 121 0.62 79.24 75.23 99.80
25 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 99.78
26 INT39212 Binding of Ttr 14 0.48 9.62 2.31 99.76
27 INT72298 Localization of Xpa 1 0.08 0.73 0.29 99.76
28 INT72299 Gene_expression of Xpa 1 0.07 0.73 0.29 99.76
29 INT82611 Negative_regulation of SRC 30 0.57 20.16 5.47 99.76
30 INT191668 Gene_expression of Phc2 5 0.32 3.25 0.85 99.74
31 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 99.72
32 INT4928 Binding of Mag 9 0.26 7.62 1.42 99.72
33 INT66043 Regulation of SPTLC2 3 0.44 1.62 1.09 99.72
34 INT169665 Gene_expression of Sp7 2 0.29 1.2 0 99.68
35 INT217102 Gene_expression of Egr2 50 0.78 10.91 3.89 99.64
36 INT11745 Protein_catabolism of Cst7 3 0.39 0.81 2.08 99.58
37 INT57379 Positive_regulation of Phosphorylation of Creb1 79 0.69 28.24 30.25 99.54
38 INT115229 Positive_regulation of Nenf 1 0.02 0.94 0.51 99.50
39 INT72296 Localization of Gas1 1 0.50 0.73 0.29 99.44
40 INT72297 Gene_expression of Gas1 1 0.48 0.73 0.29 99.44
41 INT110427 Gene_expression of Spp1 199 0.78 176.11 23.31 99.40
42 INT95318 Binding of Pain1 17 0.22 21.26 20.14 99.40
43 INT64787 Regulation of ITIH4 7 0.38 5.61 1.82 99.40
44 INT284528 Negative_regulation of POLG2 2 0.17 2.19 0.33 99.38
45 INT51444 Regulation of PMP22 2 0.44 1.39 0.07 99.36
46 INT17349 Negative_regulation of Akr1b1 41 0.59 27.03 10.65 99.34
47 INT57380 Phosphorylation of Creb1 213 0.82 66.8 71.26 99.34
48 INT67 Negative_regulation of Ddc 66 0.59 15.34 28.96 99.32
49 INT4877 Gene_expression of MME 184 0.78 122.82 24.78 99.28
50 INT81530 Gene_expression of Nfkb1 93 0.78 48.58 32.58 99.28
51 INT81531 Positive_regulation of Gene_expression of Nfkb1 27 0.69 13.9 11.04 99.28
52 INT124702 Positive_regulation of Trpv4 21 0.69 7.14 8.2 99.24
53 INT88701 Gene_expression of MMD 15 0.44 6.04 1.94 99.20
54 INT130467 Negative_regulation of Folh1 1 0.58 1.42 1.39 99.20
55 INT54924 Gene_expression of RLS 67 0.62 83.2 14.25 99.18
56 INT302703 Binding of PLAA 1 0.13 0.87 0.15 99.18
57 INT116655 Binding of NAA50 3 0.36 1.93 0.78 99.08
58 INT157121 Gene_expression of GAD2 15 0.67 7.21 5.91 99.00
59 INT78515 Negative_regulation of Mag 10 0.54 9.4 5.06 98.96
60 INT190900 Binding of Arsb 5 0.35 17.18 0.35 98.90
61 INT66004 Binding of Cnr2 35 0.48 12.82 18.63 98.88
62 INT97308 Gene_expression of TPO 15 0.65 13.26 2.12 98.88
63 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 98.88
64 INT55310 Gene_expression of Ssr1 20 0.67 3.47 2.56 98.80
65 INT36354 Localization of CTs 26 0.64 20.84 9.31 98.76
66 INT2280 Negative_regulation of TNFAIP1 70 0.43 69.43 8.36 98.72
67 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73 98.68
68 INT163742 Gene_expression of Artn 3 0.65 1.22 0.92 98.64
69 INT235725 Regulation of SRC 7 0.44 4.71 0.19 98.60
70 INT110838 Regulation of AGXT 5 0.46 2.21 1.28 98.56
71 INT61925 Negative_regulation of Adk 53 0.59 22.46 40.38 98.52
72 INT109150 Negative_regulation of Tubgcp2 4 0.38 2.04 5.12 98.52
73 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59 98.48
74 INT65907 Negative_regulation of Gene_expression of Ngf 36 0.59 19.5 20.03 98.46
75 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 98.36
76 INT312821 Binding of Ins2 2 0.37 2.13 0.46 98.36
77 INT53062 Gene_expression of Ddc 31 0.77 11.59 9.63 98.32
78 INT29045 Regulation of Etf1 10 0.05 5.93 8.7 98.32
79 INT12035 Regulation of F2 21 0.45 12.66 1.47 98.32
80 INT74389 Gene_expression of Gdnf 131 0.78 58.52 57.06 98.28
81 INT18773 Localization of ALB 117 0.80 69.18 13.8 98.28
82 INT297224 Negative_regulation of Negative_regulation of Kcnj5 1 0.11 0.74 0.27 98.28
83 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 98.20
84 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 98.20
85 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 98.20
86 INT99348 Negative_regulation of PARP1 38 0.58 30.96 3.36 98.12
87 INT217097 Regulation of Egr2 3 0.62 1.4 0.29 98.12
88 INT91121 Localization of Clstn2 1 0.69 0.38 0.26 98.04
89 INT3213 Gene_expression of Ins1 511 0.76 357.59 53.32 98.00
90 INT3911 Gene_expression of TNFAIP1 29 0.65 21.68 1.85 97.96
91 INT569 Negative_regulation of C4a 13 0.42 9.48 2.85 97.94
92 INT149930 Negative_regulation of ARTN 2 0.07 2.22 0.62 97.92
93 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 97.88
94 INT53532 Gene_expression of Lcp1 10 0.70 11.57 1.69 97.84
95 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45 97.84
96 INT4345 Gene_expression of Gtf3a 157 0.67 80.75 48.47 97.82
97 INT81955 Positive_regulation of SPTLC1 12 0.70 10.25 3.12 97.76
98 INT15007 Gene_expression of Pbrgcsf1 31 0.49 17.82 6.99 97.72
99 INT121884 Regulation of Binding of Nos1 2 0.33 1.63 2.15 97.72
100 INT79671 Positive_regulation of Gene_expression of Pbrgcsf1 8 0.32 4.25 0.57 97.72
101 INT1261 Localization of Adh1 63 0.81 19.36 16.09 97.70
102 INT107129 Positive_regulation of RLS 46 0.60 40.1 8.09 97.68
103 INT91100 Binding of SPTLC1 10 0.47 12.85 5.71 97.68
104 INT329398 Binding of Dstn 1 0.13 1.3 0.23 97.68
105 INT312831 Negative_regulation of Lck 3 0.13 2.46 0.36 97.64
106 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57 97.64
107 INT18322 Negative_regulation of Ins1 132 0.58 88.49 22.59 97.56
108 INT57882 Negative_regulation of Kcnj5 33 0.35 13.06 12.27 97.56
109 INT55224 Gene_expression of DRGX 99 0.31 67.55 67.63 97.56
110 INT62710 Gene_expression of HGF 160 0.78 88.27 26.14 97.52
111 INT74944 Positive_regulation of Gene_expression of HGF 31 0.70 17.69 6.68 97.52
112 INT15229 Positive_regulation of CNDP1 21 0.69 15.86 4.06 97.52
113 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01 97.50
114 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45 97.34
115 INT31412 Negative_regulation of Positive_regulation of Ins1 10 0.40 7.14 2.82 97.34
116 INT152525 Negative_regulation of Eef1a1 1 0.07 0.91 0.55 97.34
117 INT192423 Positive_regulation of TARM1 5 0.34 10.77 0.51 97.28
118 INT224924 Binding of TARM1 4 0.18 3.42 0.39 97.28
119 INT120997 Regulation of Npy5r 1 0.00 0.54 0.6 97.20
120 INT96744 Positive_regulation of Gene_expression of Cxcr4 14 0.68 7.92 5.75 97.16
121 INT88047 Positive_regulation of Gene_expression of Ccr2 15 0.60 10.5 8.63 97.16
122 INT8747 Positive_regulation of Ins1 221 0.69 154.28 35.15 97.14
123 INT104527 Binding of FSCN1 18 0.23 14.75 19.6 97.12
124 INT12054 Negative_regulation of MIA3 32 0.45 23.2 6.18 97.12
125 INT67890 Positive_regulation of Gene_expression of SGCG 26 0.67 9.91 6.41 97.10
126 INT53482 Gene_expression of ITIH4 75 0.77 58.87 26.05 97.04
127 INT96748 Gene_expression of GOLPH3 7 0.58 5.13 4.42 97.04
128 INT117893 Binding of Serpind1 15 0.41 24.59 2.41 97.00
129 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 96.96
130 INT16258 Gene_expression of Ntf3 121 0.78 53.93 59.03 96.96
131 INT75224 Positive_regulation of Gene_expression of Ntf3 23 0.69 11.79 13.08 96.96
132 INT51913 Regulation of Sqle 2 0.54 0.43 0.78 96.96
133 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68 96.84
134 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 96.84
135 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48 96.84
136 INT101604 Regulation of Cdk5 10 0.61 2.2 5.53 96.76
137 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82 96.74
138 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 96.68
139 INT99336 Negative_regulation of FOLH1 30 0.57 8.83 11.53 96.56
140 INT93612 Transcription of Ntrk1 2 0.52 1.31 1.26 96.52
141 INT118730 Regulation of Transcription of Ntrk1 1 0.43 0.45 0.57 96.52
142 INT90937 Negative_regulation of Gene_expression of Trpv1 34 0.59 22.74 18.12 96.48
143 INT87686 Positive_regulation of Gene_expression of Trpv1 101 0.70 72.41 69.15 96.48
144 INT96741 Gene_expression of Cxcr4 62 0.78 32.3 22.14 96.40
145 INT88046 Gene_expression of Ccr2 38 0.76 33.76 28.07 96.40
146 INT312832 Negative_regulation of Ins2 1 0.37 0.64 0.09 96.28
147 INT90171 Positive_regulation of HNB1 1 0.00 0.57 0.32 96.28
148 INT73128 Regulation of Pde5a 7 0.37 4.42 4.27 96.24
149 INT152030 Gene_expression of Postn 10 0.55 8.09 7.08 96.24
150 INT118729 Regulation of Transcription of Ngfr 1 0.36 0.45 0.57 96.20
151 INT121416 Gene_expression of Trpm8 101 0.78 52.7 47.85 96.20
152 INT159442 Positive_regulation of Gene_expression of Trpm8 10 0.70 5.86 5.34 96.20
153 INT159443 Regulation of Gene_expression of Trpm8 9 0.57 6.63 5.12 96.20
154 INT26173 Regulation of SELS 3 0.52 3.4 0.32 96.10
155 INT95427 Positive_regulation of Mmp3 39 0.70 15.28 13.36 96.00
156 INT3948 Regulation of Cck 291 0.62 58.07 255.88 95.92
157 INT62373 Negative_regulation of NGF 34 0.59 25.87 22.38 95.88
158 INT49172 Regulation of Nos1 43 0.52 27.53 23.66 95.88
159 INT80251 Binding of Nos1 21 0.30 8.24 11.31 95.88
160 INT153495 Binding of Pmp22 3 0.37 2.51 0.34 95.84
161 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67 95.76
162 INT69310 Negative_regulation of IL1A 10 0.43 7.83 5.05 95.76
163 INT175214 Gene_expression of HSPB2 21 0.72 22.84 0.81 95.72
164 INT159409 Gene_expression of PLAA 2 0.54 6.14 0.89 95.72
165 INT312973 Binding of ACADVL 1 0.23 2.35 0.17 95.72
166 INT2365 Positive_regulation of Cck 354 0.70 87.8 277.41 95.68
167 INT158837 Binding of POLG 4 0.37 4.69 0.44 95.60
168 INT5843 Positive_regulation of Gfap 184 0.70 108.2 70.21 95.52
169 INT312826 Negative_regulation of Nppc 1 0.03 1.36 0.45 95.44
170 INT43707 Positive_regulation of CCBE1 11 0.07 8.22 4.86 95.44
171 INT21877 Negative_regulation of Serpind1 3 0.52 6.85 0.93 95.36
172 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 95.32
173 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57 95.32
174 INT75742 Binding of RLS 86 0.42 95.27 19.04 95.32
175 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 95.24
176 INT194332 Localization of MFN2 2 0.74 1.45 0.15 95.16
177 INT126583 Positive_regulation of PARP1 50 0.68 41.44 7.78 95.12
178 INT19199 Negative_regulation of Rvm 16 0.37 10.07 21.73 95.12
179 INT28359 Gene_expression of Pdcd1 39 0.57 34.09 3.4 95.10
180 INT158410 Negative_regulation of Pdcd1 2 0.37 3.73 0.33 95.10
181 INT6437 Binding of YY1 154 0.47 26.3 90.46 95.04
182 INT57874 Gene_expression of Egr1 113 0.78 68.46 24.95 95.04
183 INT214 Localization of AVP 370 0.81 208.51 91.09 95.00
184 INT8959 Binding of Gnb5 17 0.40 31.38 5.1 94.96
185 INT82370 Gene_expression of Psap 1 0.77 1.72 0.22 94.88
186 INT82372 Positive_regulation of Gene_expression of Psap 1 0.69 1.08 0.14 94.88
187 INT26972 Negative_regulation of Tenc1 57 0.57 56.71 16.87 94.84
188 INT58079 Localization of Tenc1 13 0.68 5.9 4.75 94.84
189 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 94.76
190 INT117600 Positive_regulation of Trpm8 65 0.70 31.96 24.46 94.76
191 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 94.68
192 INT15367 Gene_expression of OPA1 35 0.67 24.9 5.45 94.68
193 INT82308 Negative_regulation of HADHA 2 0.38 1.52 0.91 94.64
194 INT118440 Gene_expression of TRPV4 20 0.71 7.33 6.01 94.64
195 INT209259 Regulation of Gene_expression of TRPV4 1 0.22 0.93 0.19 94.64
196 INT36799 Negative_regulation of Ighm 21 0.41 17.47 3.65 94.56
197 INT41789 Negative_regulation of Moxd2 6 0.57 4.03 2.49 94.56
198 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 94.48
199 INT97376 Gene_expression of RT1-M4 11 0.33 6.79 8.51 94.48
200 INT194298 Gene_expression of DHPS 1 0.62 8.84 0.37 94.40
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