D:Persistent Vegetative State

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pChart

Disease Term
Synonyms Minimally Conscious State, MINIMALLY CONSCIOUS STATES, PERMANENT VEGETATIVE STATE, PERMANENT VEGETATIVE STATES, Persistent Unawareness State, PERSISTENT UNAWARENESS STATES, Persistent Vegetative States, Post Comatose Unawareness State, Post Comatose Unawareness States, Post Traumatic Unawareness Prolonged, Post Traumatic Unawareness State
Documents 118
Hot Single Events 31
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Persistent Vegetative State. They are ordered first by their relevance to Persistent Vegetative State and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT142709 Binding of TWIST1 and CEBPZ 2 0.17 1.16 0.95 81.68
2 INT152158 NENF Regulation of TWIST1 1 0.01 0.33 0.4 63.04
3 INT254133 PLEC Regulation of MCRS1 1 0.03 0.33 0.13 30.80
4 INT317427 IFN1@ Positive_regulation of ISYNA1 1 0.12 0.49 0.45 5.00
5 INT317426 Binding of CSF2 and PML 1 0.08 1.25 0.06 5.00
6 INT337118 MCRS1 Negative_regulation of C7orf49 1 0.00 0.66 0.04 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Persistent Vegetative State. They are ordered first by their pain relevance and then by number of times they were reported in Persistent Vegetative State. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT193582 Gene_expression of PVR 21 0.58 14 2.39 100.00
2 INT177910 Gene_expression of AS3MT 7 0.23 6.94 1.08 100.00
3 INT61680 Positive_regulation of PVR 23 0.60 23.27 3.86 100.00
4 INT28929 Negative_regulation of PVR 22 0.57 16.64 1.07 100.00
5 INT177909 Positive_regulation of AS3MT 2 0.17 1.84 0.09 100.00
6 INT223937 Transcription of PVR 1 0.60 1.53 0.14 100.00
7 INT211830 Binding of PVR 3 0.32 2.26 0.03 100.00
8 INT90670 Positive_regulation of KRT1 10 0.44 6.25 1.16 99.16
9 INT286998 Negative_regulation of AS3MT 1 0.15 0.78 0.04 98.66
10 INT94545 Positive_regulation of C7orf49 37 0.69 12.91 11.19 98.50
11 INT123463 Gene_expression of ATP5G3 5 0.37 2.25 0.75 98.16
12 INT83468 Gene_expression of ELK3 22 0.66 2.91 2.03 98.00
13 INT134811 Gene_expression of ICA1 22 0.44 6.47 2.42 95.36
14 INT289211 Localization of MFGE8 11 0.09 0.19 2.69 94.64
15 INT313984 Localization of Ba4 1 0.07 0.09 0.18 94.64
16 INT289202 Gene_expression of TRIO 5 0.23 1.21 1.49 92.96
17 INT177630 Regulation of Gene_expression of NFKBIL1 1 0.37 0.92 0.09 92.84
18 INT13362 Gene_expression of NFKBIL1 12 0.59 3.79 3.99 92.44
19 INT141475 Negative_regulation of Gene_expression of TWIST1 5 0.41 3.94 0.97 92.08
20 INT64766 Gene_expression of TWIST1 41 0.76 37.89 3.4 92.08
21 INT9199 Positive_regulation of CEBPZ 111 0.67 30.99 28.45 91.04
22 INT117204 Gene_expression of Tcm 39 0.58 10.58 4.88 90.28
23 INT4988 Gene_expression of KRT1 64 0.77 43.4 4.12 90.12
24 INT22532 Positive_regulation of Bsp 9 0.70 1.59 8.73 88.08
25 INT289208 Gene_expression of MFGE8 13 0.08 0.25 3.7 86.32
26 INT313982 Gene_expression of Ba6 1 0.08 0.09 0.2 85.68
27 INT165005 Binding of REST 26 0.43 2.81 1.39 84.64
28 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 84.36
29 INT15652 Positive_regulation of ENO2 37 0.68 33.39 5.02 83.56
30 INT16395 Gene_expression of CEBPZ 30 0.57 11.02 6.66 82.48
31 INT3793 Regulation of CEBPZ 59 0.61 20.91 15.83 81.68
32 INT352671 Positive_regulation of TRIO 1 0.02 0.51 0.33 79.44
33 INT184890 Regulation of MCRS1 35 0.22 44.35 13.78 78.88
34 INT140436 Binding of TWIST1 5 0.39 2.34 0.47 77.56
35 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 75.00
36 INT173967 Gene_expression of Mri1 26 0.43 16.67 6.45 73.28
37 INT151427 Gene_expression of ADC 31 0.55 21.86 3.81 72.68
38 INT151742 Positive_regulation of PLEC 3 0.41 0.89 0.17 68.20
39 INT289209 Regulation of MFGE8 3 0.05 0.2 1.13 67.12
40 INT313985 Regulation of Ba6 1 0.06 0.07 0.2 65.84
41 INT313983 Regulation of Ba3 1 0.02 0.07 0.2 65.44
42 INT180139 Protein_catabolism of SIRT2 11 0.14 1.1 0.72 64.16
43 INT352670 Binding of TRIO 1 0.02 0.29 0.37 60.00
44 INT342016 Negative_regulation of TRIO 2 0.02 1.24 0.63 59.84
45 INT177600 Gene_expression of C7orf49 21 0.52 7.1 6.92 52.48
46 INT70265 Regulation of MRI1 42 0.39 30.95 14.18 51.80
47 INT188759 Positive_regulation of Gene_expression of ADC 3 0.28 2.7 0.5 51.28
48 INT50070 Negative_regulation of NFKBIL1 14 0.48 3.76 5.92 50.00
49 INT62510 Positive_regulation of MCS 32 0.60 11.79 5.45 50.00
50 INT13329 Localization of NFKBIL1 3 0.69 0 0.82 50.00
51 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 49.24
52 INT59454 Regulation of Gene_expression of CSF2 22 0.52 19.67 2.69 44.72
53 INT77523 Positive_regulation of ADC 14 0.63 13.81 1.81 40.00
54 INT134673 Gene_expression of SYNM 16 0.75 2.72 1.62 37.36
55 INT274007 Positive_regulation of Gene_expression of SYNM 2 0.27 0.12 0.2 37.36
56 INT313988 Positive_regulation of Gene_expression of C7orf49 1 0.03 0.12 0.03 37.36
57 INT123970 Negative_regulation of BAG3 11 0.38 5.29 2.6 34.96
58 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 34.40
59 INT68338 Gene_expression of PLEC 4 0.75 0.44 0.32 32.48
60 INT14301 Binding of CSF2 82 0.48 67.95 8.98 32.28
61 INT254136 Regulation of PLEC 1 0.23 0.33 0.13 30.64
62 INT287251 Negative_regulation of PKN1 6 0.01 1.86 0.25 26.72
63 INT227762 Binding of AS3MT 2 0.13 1.19 0.15 24.52
64 INT286999 Positive_regulation of Gene_expression of AS3MT 1 0.17 1.14 0 24.52
65 INT203636 Positive_regulation of CD2AP 4 0.13 1.27 0.28 23.84
66 INT16396 Negative_regulation of CEBPZ 76 0.48 30.03 21.6 23.16
67 INT93077 Negative_regulation of Localization of S100B 3 0.57 0.58 0.2 12.32
68 INT17742 Localization of S100B 44 0.80 17.14 4.65 11.88
69 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
70 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
71 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
72 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 5.00
73 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 5.00
74 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
75 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28 5.00
76 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 5.00
77 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 5.00
78 INT72923 Positive_regulation of MCRS1 72 0.50 99.19 30.36 5.00
79 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
80 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
81 INT48853 Positive_regulation of BDNF 82 0.69 43.92 27.99 5.00
82 INT14690 Localization of CSF2 124 0.80 85.17 27.26 5.00
83 INT76095 Positive_regulation of ISYNA1 117 0.55 79.73 25.86 5.00
84 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 5.00
85 INT17275 Gene_expression of HIVEP1 267 0.75 232.07 24.06 5.00
86 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05 5.00
87 INT14700 Regulation of IFNA1 111 0.45 66.16 21.52 5.00
88 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 5.00
89 INT105021 Binding of GOPC 187 0.40 60.39 20.38 5.00
90 INT184895 Gene_expression of MCRS1 46 0.42 56.03 19.44 5.00
91 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 5.00
92 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 5.00
93 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8 5.00
94 INT635 Negative_regulation of MAOB 51 0.59 24.5 12.66 5.00
95 INT112003 Localization of ROS1 94 0.73 66.32 12.16 5.00
96 INT36287 Binding of CD4 96 0.47 58.93 11.88 5.00
97 INT72924 Negative_regulation of MCRS1 27 0.19 33.59 10.29 5.00
98 INT170333 Binding of IFN1@ 68 0.47 49.01 9.72 5.00
99 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 5.00
100 INT108931 Negative_regulation of BDNF 38 0.59 19.61 8.84 5.00
101 INT175554 Binding of MCRS1 21 0.23 25.2 8.59 5.00
102 INT939 Gene_expression of PAEP 86 0.77 31.02 8.59 5.00
103 INT18524 Regulation of Gene_expression of IFNA1 37 0.44 18.79 7.62 5.00
104 INT162253 Gene_expression of BAG3 30 0.59 20.16 7.18 5.00
105 INT25022 Binding of PAEP 66 0.42 22.83 6.59 5.00
106 INT22128 Positive_regulation of HIVEP1 61 0.43 70.52 6.07 5.00
107 INT91217 Positive_regulation of BAG3 22 0.48 16.57 6.06 5.00
108 INT15803 Regulation of IFNG 21 0.44 12.57 5.98 5.00
109 INT122653 Positive_regulation of Gene_expression of CD4 48 0.68 22.5 5.96 5.00
110 INT77281 Negative_regulation of HIVEP1 132 0.49 102.78 5.36 5.00
111 INT162254 Regulation of BAG3 28 0.41 18.12 4.75 5.00
112 INT7083 Positive_regulation of HBM 35 0.66 20.96 4.3 5.00
113 INT86998 Regulation of HIVEP1 49 0.44 37.83 4 5.00
114 INT10744 Positive_regulation of PIF1 11 0.66 3.95 3.69 5.00
115 INT200385 Negative_regulation of ADC 19 0.18 16.56 3.6 5.00
116 INT170528 Negative_regulation of Gene_expression of CD4 25 0.41 17.98 3.6 5.00
117 INT76869 Localization of PAEP 15 0.73 6.57 3.36 5.00
118 INT2837 Regulation of PAEP 17 0.53 7.84 3.17 5.00
119 INT14086 Binding of SERPINB1 18 0.34 4.32 3.13 5.00
120 INT45303 Binding of SYNM 4 0.40 2.14 3.07 5.00
121 INT102233 Gene_expression of MMP7 40 0.76 15.78 2.93 5.00
122 INT203183 Negative_regulation of C7orf49 4 0.05 3.23 2.9 5.00
123 INT4313 Localization of PIF1 8 0.39 0.38 2.83 5.00
124 INT200384 Regulation of ADC 12 0.25 5.46 2.41 5.00
125 INT29094 Binding of C3 39 0.37 12.65 2.27 5.00
126 INT43612 Regulation of SERPINB1 12 0.11 3.26 2.21 5.00
127 INT25265 Transcription of HIVEP1 30 0.45 28.12 2.08 5.00
128 INT43900 Gene_expression of RASA1 13 0.58 12 2.03 5.00
129 INT135961 Positive_regulation of Hc 8 0.67 3.67 1.87 5.00
130 INT153591 Binding of C7orf49 10 0.47 2.77 1.87 5.00
131 INT180134 Gene_expression of SIRT2 70 0.11 6.95 1.84 5.00
132 INT163613 Transcription of CSF2 16 0.60 12.98 1.62 5.00
133 INT102428 Binding of C2 17 0.32 5.12 1.58 5.00
134 INT28367 Positive_regulation of REST 10 0.54 2.07 1.52 5.00
135 INT31949 Negative_regulation of PIF1 5 0.05 4 1.38 5.00
136 INT127283 Regulation of Gene_expression of HMOX1 14 0.61 11.8 1.28 5.00
137 INT176594 Gene_expression of SRA1 20 0.35 9.65 1.15 5.00
138 INT139527 Positive_regulation of Gene_expression of PAEP 16 0.43 4.66 0.98 5.00
139 INT150879 Gene_expression of PTCRA 12 0.77 2.1 0.94 5.00
140 INT180136 Localization of SIRT2 15 0.12 1.42 0.88 5.00
141 INT171879 Binding of ENOX1 9 0.03 3.37 0.77 5.00
142 INT30978 Binding of CA9 3 0.20 3.05 0.75 5.00
143 INT78329 Binding of ADC 7 0.31 7.57 0.73 5.00
144 INT180149 Positive_regulation of SRA1 7 0.40 2.65 0.65 5.00
145 INT94423 Binding of ALAS2 4 0.32 2.1 0.61 5.00
146 INT72707 Binding of PIF1 2 0.35 0.42 0.6 5.00
147 INT242259 Negative_regulation of Positive_regulation of CEBPZ 4 0.48 1.44 0.59 5.00
148 INT324672 Negative_regulation of Gene_expression of CEBPZ 2 0.36 2.75 0.48 5.00
149 INT7248 Localization of RASA1 4 0.61 2.52 0.47 5.00
150 INT180138 Negative_regulation of Gene_expression of SIRT2 2 0.07 0.19 0.41 5.00
151 INT180142 Negative_regulation of SIRT2 10 0.07 0.19 0.41 5.00
152 INT180145 Gene_expression of THOP1 15 0.28 5.94 0.36 5.00
153 INT4314 Positive_regulation of Localization of PIF1 2 0.13 0.08 0.34 5.00
154 INT313986 Positive_regulation of Gene_expression of BAG3 2 0.06 0.91 0.33 5.00
155 INT3321 Positive_regulation of ALAS2 10 0.51 3.08 0.32 5.00
156 INT241803 Positive_regulation of GBA 6 0.70 2.41 0.3 5.00
157 INT180144 Binding of SIRT2 57 0.06 1.29 0.27 5.00
158 INT180141 Localization of SRA1 3 0.07 1.66 0.27 5.00
159 INT241800 Negative_regulation of Positive_regulation of GBA 2 0.36 1.05 0.24 5.00
160 INT134945 Binding of GBA 3 0.37 3.69 0.24 5.00
161 INT3323 Gene_expression of ALAS2 10 0.58 7.51 0.21 5.00
162 INT185836 Positive_regulation of Gene_expression of MMP7 4 0.43 0.41 0.2 5.00
163 INT335032 Binding of THEG 1 0.04 2.4 0.2 5.00
164 INT182647 Positive_regulation of EPB41 2 0.01 0.77 0.2 5.00
165 INT248772 Negative_regulation of Binding of CSF2 4 0.39 5.16 0.19 5.00
166 INT175663 Positive_regulation of SIRT2 56 0.14 3.58 0.17 5.00
167 INT337121 Negative_regulation of Regulation of CEBPZ 1 0.31 0.81 0.15 5.00
168 INT180137 Gene_expression of DIABLO 1 0.03 0.13 0.13 5.00
169 INT180135 Gene_expression of PIF1 1 0.04 0.22 0.11 5.00
170 INT185498 Regulation of Positive_regulation of ENO2 1 0.26 0.5 0.1 5.00
171 INT227763 Positive_regulation of KLK4 8 0.47 1.39 0.1 5.00
172 INT234676 Gene_expression of SNCG 4 0.78 63.59 0.08 5.00
173 INT242260 Regulation of Positive_regulation of CEBPZ 2 0.35 0.55 0.07 5.00
174 INT213624 Localization of ALAS2 1 0.05 0 0.07 5.00
175 INT61978 Regulation of PIF1 2 0.22 0.15 0.06 5.00
176 INT337123 Phosphorylation of CEBPZ 1 0.59 0.64 0.04 5.00
177 INT17295 Regulation of Gene_expression of CEBPZ 2 0.33 0.57 0.04 5.00
178 INT313987 Localization of GCNT2 1 0.14 0 0 5.00
179 INT180140 Regulation of SIRT2 3 0.04 0 0 5.00
180 INT213625 Regulation of Gene_expression of ALAS2 1 0.03 0.06 0 5.00
181 INT180146 Positive_regulation of Binding of SIRT2 2 0.08 0 0 5.00
182 INT180148 Phosphorylation of SERPINB1 1 0.12 0 0 5.00
183 INT180147 Negative_regulation of Gene_expression of PIF1 1 0.02 0 0 5.00
184 INT180143 Phosphorylation of SIRT2 1 0.13 0 0 5.00
185 INT296418 Binding of PPIH 1 0.02 1.31 0 5.00
186 INT3322 Positive_regulation of Gene_expression of ALAS2 4 0.43 3.25 0 5.00
187 INT330754 Regulation of KLK4 1 0.06 0.48 0 5.00
188 INT335031 Positive_regulation of Gene_expression of RASA1 1 0.09 1.49 0 5.00
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