D:Personality Disorder

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Disease Term
Synonyms Anti Social Personality, Antisocial Personality, As If Personality, Avoidant Personality, Avoidant Personality Disorder, Avoidant Personality Disorders, BORDERLINE PERSONALITY, Cyclothymic Personality, DEPENDENT PERSONALITY, DEPRESSIVE PERSONALITY, Dissociative Identity Disorder
Documents 556
Hot Single Events 38
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Personality Disorder. They are ordered first by their relevance to Personality Disorder and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT217075 Binding of Acsm3 and Slc26a4 1 0.04 2.11 0.04 94.72
2 INT217074 Binding of Acsm3 and Axin1 1 0.00 5.37 0.17 88.76
3 INT202254 Binding of COMT and DRD2 1 0.41 0.23 0.86 5.00
4 INT164364 Binding of DRD2 and SUGT1 2 0.06 0.33 0.77 5.00
5 INT292598 CNR1 Regulation of ABAT 1 0.08 0.32 0.75 5.00
6 INT292599 CNR1 Regulation of Localization of ABAT 1 0.08 0.32 0.75 5.00
7 INT255463 Binding of Avp and Avpr1a 1 0.06 0.67 0.54 5.00
8 INT184878 Binding of Lmo1 and ADHD1 2 0.04 2.33 0.53 5.00
9 INT189859 Binding of SLC6A3 and ADHD1 2 0.32 0.68 0.48 5.00
10 INT138384 Binding of Htr1b and ADHD1 2 0.07 1.46 0.42 5.00
11 INT242363 Binding of Il1a and Il1rn 1 0.05 0.19 0.35 5.00
12 INT258762 Binding of Dbh and ADHD1 1 0.08 1.61 0.34 5.00
13 INT198566 Ddit4l Regulation of Axin1 1 0.03 1 0.31 5.00
14 INT258763 Binding of Drd5 and ADHD1 1 0.07 1.11 0.31 5.00
15 INT258764 Binding of Drd4 and ADHD1 1 0.08 1.11 0.31 5.00
16 INT293900 TYRP1 Regulation of IGKC 1 0.01 0.11 0.27 5.00
17 INT258766 Binding of Csf2 and ADHD1 1 0.01 0.69 0.27 5.00
18 INT258757 Binding of Drd2 and Rends1 1 0.00 1.26 0.25 5.00
19 INT202252 COMT Regulation of DRD2 1 0.31 0 0.21 5.00
20 INT293901 Positive_regulation of TYRP1 Regulation of IGKC 1 0.02 0.06 0.15 5.00
21 INT202253 Binding of COMT and TCN1 1 0.16 0 0.12 5.00
22 INT258761 Binding of Slc6a3 and ADHD1 1 0.03 0.51 0.12 5.00
23 INT202255 Binding of DRD2 and TCN1 1 0.16 0 0.12 5.00
24 INT258767 Binding of Drd2 and ADHD1 1 0.11 1.14 0.11 5.00
25 INT258765 Lmo1 Regulation of ADHD1 1 0.05 1.98 0.09 5.00
26 INT276438 Binding of OPN1SW and MYP1 1 0.12 1.21 0.09 5.00
27 INT280451 IER5 Positive_regulation of Phc1 1 0.00 0.56 0.09 5.00
28 INT258758 Binding of Drd4 and Lmo1 1 0.04 0.64 0.08 5.00
29 INT258756 Binding of Drd5 and Lmo1 1 0.03 0.64 0.08 5.00
30 INT258768 Drd2 Regulation of ADHD1 1 0.14 0.79 0.07 5.00
31 INT290727 Binding of Prdm6 and Arsi 1 0.01 0.17 0.04 5.00
32 INT293899 UPF1 Positive_regulation of Gene_expression of APOB 1 0.01 0 0.04 5.00
33 INT202573 Binding of DIO2 and DRD4 1 0.07 0.09 0.03 5.00
34 INT202572 NOVA2 Regulation of DDT 1 0.03 0.14 0 5.00
35 INT204927 Binding of LGMN and IL33 1 0.00 0.52 0 5.00
36 INT202571 Binding of DRD2 and DRD4 1 0.41 0.76 0 5.00
37 INT237728 CDR1 Regulation of ADHD1 1 0.03 0.98 0 5.00
38 INT273596 SMG1 Regulation of Negative_regulation of ADHD1 1 0.16 0.41 0 5.00
39 INT251822 Binding of POLG and C10orf2 1 0.42 0.29 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Personality Disorder. They are ordered first by their pain relevance and then by number of times they were reported in Personality Disorder. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT26621 Negative_regulation of Slc26a4 2 0.32 2.51 0.3 100.00
2 INT181258 Gene_expression of Slc26a4 4 0.19 3.26 0.21 100.00
3 INT181262 Positive_regulation of Slc26a4 1 0.13 1.3 0.08 100.00
4 INT181260 Regulation of Slc26a4 2 0.30 1.67 0.03 100.00
5 INT181259 Regulation of Negative_regulation of Slc26a4 1 0.08 0.84 0.07 100.00
6 INT243198 Gene_expression of ZNRF1 2 0.09 4.05 0.09 100.00
7 INT53468 Binding of Acsm3 26 0.24 20.87 2.95 99.98
8 INT171019 Gene_expression of SMPD1 26 0.27 12.08 5.08 99.90
9 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 99.88
10 INT203682 Negative_regulation of MROS 5 0.36 3.71 0.74 99.84
11 INT158 Localization of Prl 2431 0.81 378.96 952.2 99.72
12 INT7581 Binding of ADHD1 132 0.46 135.1 19.73 99.68
13 INT57549 Gene_expression of GNPTAB 49 0.65 57.5 9.05 99.52
14 INT63132 Positive_regulation of Pd 10 0.13 5.86 3.15 99.40
15 INT147195 Negative_regulation of Smcp 4 0.38 3.53 0.65 98.84
16 INT80419 Gene_expression of Kdm5d 50 0.62 22.49 6.1 96.68
17 INT1530 Regulation of Gh 382 0.61 115.96 112.47 96.48
18 INT61713 Gene_expression of NCKIPSD 5 0.72 2.43 0.19 96.04
19 INT153417 Gene_expression of DDOST 6 0.67 1.81 2.18 95.96
20 INT1243 Regulation of ADRB2 16 0.54 1.84 5.66 95.88
21 INT162 Regulation of Prl 794 0.62 165.01 322.24 95.48
22 INT119991 Regulation of MROS 5 0.23 4.75 0.48 95.12
23 INT619 Positive_regulation of Positive_regulation of Prl 116 0.70 22.69 45.06 95.00
24 INT13454 Positive_regulation of Positive_regulation of Gh 49 0.68 14.53 18.49 95.00
25 INT37729 Positive_regulation of Positive_regulation of TSHR 1 0.01 0.39 0.5 95.00
26 INT112730 Positive_regulation of ZNRF1 3 0.06 2.97 0.24 94.96
27 INT4682 Positive_regulation of EGOT 2 0.42 2.32 1.28 94.16
28 INT219950 Negative_regulation of Gene_expression of SRC 2 0.29 1.32 1.15 94.00
29 INT151758 Gene_expression of PYCARD 91 0.63 14.54 24.27 92.72
30 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 92.36
31 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 92.36
32 INT33516 Positive_regulation of TSHR 4 0.49 2.5 0.93 92.36
33 INT170239 Gene_expression of VARS 12 0.07 2.15 0.47 91.12
34 INT84911 Gene_expression of SUGT1 43 0.11 19.85 4.54 90.92
35 INT100688 Gene_expression of SRC 28 0.75 15.51 3.08 90.24
36 INT193504 Positive_regulation of OPN1SW 11 0.58 7.44 1.47 85.76
37 INT52179 Regulation of Lbp 39 0.61 25.4 18.32 84.12
38 INT307264 Gene_expression of PHF1 3 0.65 0.18 0.04 83.28
39 INT5871 Binding of IFNA2 38 0.48 20.35 6.46 79.76
40 INT282635 Positive_regulation of Binding of ADHD1 4 0.40 3.62 0.24 79.36
41 INT251827 Regulation of POLG 3 0.59 2.94 0.04 79.36
42 INT18647 Localization of YY1 16 0.78 4.04 9.77 79.00
43 INT195599 Binding of PASK 15 0.36 17.35 1.82 78.72
44 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 75.64
45 INT33096 Negative_regulation of Gene_expression of ACE 9 0.43 2.84 1.93 75.64
46 INT210125 Regulation of Axin1 1 0.02 2.45 0.46 75.36
47 INT246706 Binding of Salc1 5 0.08 3.29 0.52 71.84
48 INT242113 Gene_expression of EGOT 1 0.41 3.06 0.71 70.64
49 INT180487 Binding of SLITRK1 2 0.39 3.91 0 70.32
50 INT157932 Positive_regulation of ADHD1 46 0.48 52.18 6.13 69.40
51 INT57150 Regulation of SCLY 3 0.45 4.2 1.12 68.80
52 INT196993 Binding of TMEM200A 9 0.22 1.76 0.39 68.72
53 INT232667 Binding of Pd 17 0.16 20.76 3.58 68.08
54 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 66.32
55 INT3161 Regulation of Localization of Gh 163 0.61 35.43 59.45 66.32
56 INT217070 Gene_expression of Acsm3 8 0.25 6.27 1.75 65.20
57 INT1893 Localization of Gh 1041 0.79 340.23 256.58 64.88
58 INT251831 Positive_regulation of C10orf2 1 0.50 1.23 0.08 63.80
59 INT196996 Localization of TMEM200A 8 0.50 1.62 0.47 63.52
60 INT20950 Positive_regulation of PC 12 0.60 2.76 1.19 63.40
61 INT57368 Regulation of ADHD1 39 0.50 42.23 5.01 62.64
62 INT756 Gene_expression of C3 138 0.75 100.6 19.2 62.56
63 INT262348 Gene_expression of Lgsn 12 0.58 12.64 2.08 62.52
64 INT251829 Positive_regulation of POLG 1 0.53 1.5 0.08 62.32
65 INT183903 Binding of BAS 2 0.06 2.14 1.06 59.84
66 INT183902 Gene_expression of BAS 4 0.31 1.06 0.98 59.84
67 INT278527 Gene_expression of NEO1 1 0.04 1.51 0.13 57.64
68 INT122953 Gene_expression of COMT 65 0.77 25.84 40.49 57.04
69 INT10142 Gene_expression of ANXA3 4 0.35 3.1 0.54 56.24
70 INT184853 Gene_expression of ADHD1 87 0.65 89.2 11.8 55.20
71 INT242110 Regulation of IGKV1-22 2 0.06 2.02 0.52 54.80
72 INT190487 Negative_regulation of SCLY 3 0.08 2.12 0.46 54.72
73 INT278526 Positive_regulation of Gene_expression of ANXA3 1 0.08 0.52 0 52.68
74 INT181587 Negative_regulation of OPN1SW 12 0.51 4.36 0.89 52.44
75 INT50309 Binding of Il1a 22 0.40 5.4 4.49 51.84
76 INT13041 Binding of Htr1b 14 0.47 4.92 7.95 50.00
77 INT66933 Binding of AXIN1 6 0.32 1.8 0.16 50.00
78 INT196992 Regulation of Localization of TMEM200A 1 0.05 0.2 0.05 49.88
79 INT210123 Localization of Axin1 1 0.04 0.84 0.17 49.36
80 INT217071 Localization of Acsm3 1 0.08 0.46 0.13 47.44
81 INT181588 Regulation of OPN1SW 14 0.39 8.32 3.59 43.88
82 INT169348 Gene_expression of SCLY 8 0.11 6.49 1.33 43.44
83 INT101022 Regulation of Il1rn 5 0.44 2.15 1.21 43.20
84 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 43.04
85 INT197512 Gene_expression of ABCA4 19 0.75 7.08 0.57 42.72
86 INT251828 Negative_regulation of C10orf2 3 0.37 2.87 0.41 40.68
87 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38 40.56
88 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 39.96
89 INT114741 Binding of PRB1 19 0.36 5.44 1 39.88
90 INT145364 Negative_regulation of AXIN1 2 0.33 0.52 0.08 39.84
91 INT294014 Regulation of AXIN1 3 0.24 1.04 0.08 39.84
92 INT49774 Binding of DRD2 48 0.48 17.42 20.73 37.16
93 INT177992 Positive_regulation of SNRNP70 28 0.49 16.14 4.28 35.12
94 INT150867 Regulation of COPD 54 0.48 71.38 8.8 34.96
95 INT179686 Regulation of Gene_expression of COPD 10 0.34 14.1 1.52 34.96
96 INT125980 Binding of CFD 8 0.42 10.96 1.39 34.76
97 INT138715 Gene_expression of POLG 12 0.66 6.97 0.23 34.48
98 INT47710 Negative_regulation of GRIN1 71 0.57 25.57 34.24 34.00
99 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 34.00
100 INT290726 Binding of Prkdc 1 0.03 1.05 0.13 30.64
101 INT95048 Negative_regulation of ADHD1 61 0.51 56.01 5.62 26.80
102 INT292609 Negative_regulation of Positive_regulation of DNMT3B 1 0.22 1.3 0.07 26.24
103 INT264035 Regulation of Lgsn 5 0.39 6.2 0.86 25.96
104 INT2005 Positive_regulation of Gene_expression of PRL 55 0.70 21.4 13.44 25.56
105 INT73117 Positive_regulation of DNMT3B 20 0.47 10.31 5.31 25.36
106 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 24.96
107 INT196994 Regulation of TMEM200A 9 0.17 2.23 0.61 24.68
108 INT7439 Positive_regulation of CFP 52 0.67 19.97 17.87 24.40
109 INT5966 Localization of Il1a 50 0.78 22.91 26.54 23.44
110 INT221129 Gene_expression of IGKV1-22 5 0.22 1.73 0.78 21.36
111 INT198565 Regulation of Ddit4l 1 0.06 2.36 0.45 20.24
112 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 19.72
113 INT134673 Gene_expression of SYNM 16 0.75 2.72 1.62 19.56
114 INT193405 Gene_expression of OFC1 14 0.53 3.33 1.42 19.56
115 INT76683 Positive_regulation of Il1rn 9 0.51 9.3 4.41 18.16
116 INT131928 Localization of Il1rn 3 0.74 2.22 2.24 18.16
117 INT147412 Binding of DRD4 11 0.47 7.57 2.77 15.48
118 INT217072 Negative_regulation of Acsm3 5 0.29 6.15 1.59 13.12
119 INT177611 Binding of EGOT 2 0.23 1.72 0.62 6.40
120 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 5.00
121 INT477 Localization of Avp 813 0.81 131.58 300.4 5.00
122 INT1562 Localization of Crh 499 0.81 126.74 236.68 5.00
123 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 5.00
124 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8 5.00
125 INT2910 Regulation of Abat 169 0.62 36.95 153.53 5.00
126 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69 5.00
127 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
128 INT425 Localization of PRL 455 0.81 189.64 144.8 5.00
129 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 5.00
130 INT4658 Binding of OPRM1 188 0.48 25.96 136.24 5.00
131 INT1026 Binding of Lbp 207 0.48 150.96 119.16 5.00
132 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
133 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 5.00
134 INT5940 Negative_regulation of Avp 236 0.59 67.86 101.2 5.00
135 INT1639 Negative_regulation of OPRM1 107 0.59 13.86 90.37 5.00
136 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12 5.00
137 INT7528 Regulation of OPRM1 100 0.62 20.63 80.57 5.00
138 INT14049 Positive_regulation of GRIN1 102 0.70 48.31 71.06 5.00
139 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 5.00
140 INT253 Regulation of PRL 184 0.62 47.27 65.79 5.00
141 INT6894 Gene_expression of CNR1 168 0.78 74.07 62.84 5.00
142 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36 5.00
143 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82 5.00
144 INT96533 Gene_expression of Slc1a3 72 0.78 26.85 55.31 5.00
145 INT5704 Binding of Slc3a1 78 0.43 8.52 51.78 5.00
146 INT62630 Positive_regulation of CNR1 86 0.70 40.34 51.51 5.00
147 INT19488 Localization of ABAT 56 0.69 21.51 50.56 5.00
148 INT1028 Positive_regulation of Lbp 102 0.69 67.86 46.05 5.00
149 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 5.00
150 INT2783 Gene_expression of Slc3a1 86 0.65 8.84 45.4 5.00
151 INT42980 Gene_expression of GAD1 139 0.69 94.77 45.11 5.00
152 INT1564 Localization of OPRM1 41 0.80 8.03 44.67 5.00
153 INT2531 Positive_regulation of Cebpz 166 0.00 43.08 38.86 5.00
154 INT11439 Positive_regulation of Csf2 105 0.69 62.63 37.77 5.00
155 INT6417 Negative_regulation of ABAT 49 0.51 19.6 36.81 5.00
156 INT2416 Negative_regulation of MAOA 92 0.59 42.24 36.5 5.00
157 INT13501 Binding of Drd2 65 0.48 23.76 35.6 5.00
158 INT316 Regulation of Cebpz 105 0.00 27.21 35.41 5.00
159 INT2296 Positive_regulation of Gene_expression of Prl 137 0.70 36.96 35.39 5.00
160 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 5.00
161 INT3913 Positive_regulation of ABAT 47 0.69 22.73 33.4 5.00
162 INT6683 Gene_expression of Drd2 64 0.78 11.31 32.28 5.00
163 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22 5.00
164 INT719 Negative_regulation of SGCG 96 0.57 47.91 30.22 5.00
165 INT894 Binding of Avp 84 0.48 29.16 29.63 5.00
166 INT169180 Binding of SNRNP70 204 0.47 119.1 29.3 5.00
167 INT48853 Positive_regulation of BDNF 82 0.69 43.92 27.99 5.00
168 INT177581 Regulation of Fig4 113 0.41 39.26 27.75 5.00
169 INT2650 Positive_regulation of Slc3a1 50 0.57 2.95 27.52 5.00
170 INT36428 Binding of Chdh 42 0.47 48.04 26.54 5.00
171 INT12392 Regulation of Slc3a1 45 0.36 7.57 25.66 5.00
172 INT12484 Binding of Drd2 45 0.48 15.17 24.72 5.00
173 INT56686 Regulation of Vta1 26 0.44 3.43 24.48 5.00
174 INT6441 Positive_regulation of CRH 98 0.69 57.22 24.12 5.00
175 INT11746 Positive_regulation of Il1a 65 0.63 42.94 23.54 5.00
176 INT6270 Binding of HTR1D 55 0.47 9.54 22.86 5.00
177 INT5905 Negative_regulation of ELANE 113 0.59 47.43 22.09 5.00
178 INT16396 Negative_regulation of CEBPZ 76 0.48 30.03 21.6 5.00
179 INT5916 Positive_regulation of HTR1A 51 0.67 18.27 21.38 5.00
180 INT61825 Negative_regulation of Slc6a3 47 0.59 6.52 21.27 5.00
181 INT7470 Positive_regulation of Gene_expression of Avp 37 0.70 19.55 19.96 5.00
182 INT14436 Gene_expression of Dbh 42 0.72 9.9 19.85 5.00
183 INT58477 Gene_expression of Chdh 33 0.74 39.48 19.78 5.00
184 INT135629 Binding of COMT 33 0.48 16.68 19.37 5.00
185 INT103469 Positive_regulation of Gene_expression of BDNF 59 0.67 24.39 18.36 5.00
186 INT5967 Negative_regulation of Il1a 51 0.57 27.09 18.24 5.00
187 INT97984 Negative_regulation of SLC6A4 45 0.59 15.43 18.09 5.00
188 INT18621 Binding of ABAT 28 0.36 9.88 18.04 5.00
189 INT21132 Gene_expression of GABRB3 36 0.33 11.32 17.61 5.00
190 INT13790 Binding of HTR1A 52 0.47 18.83 17.59 5.00
191 INT164366 Localization of NLRP1 26 0.71 5.9 16.54 5.00
192 INT1752 Negative_regulation of Ache 109 0.59 42.05 15.73 5.00
193 INT7952 Localization of Slc3a1 32 0.81 1.28 15.69 5.00
194 INT57734 Binding of SLC6A4 36 0.48 11.94 15.42 5.00
195 INT54356 Regulation of Slc6a3 48 0.58 5.86 15.24 5.00
196 INT3002 Binding of SUGT1 62 0.24 55.9 14.91 5.00
197 INT49606 Gene_expression of Il1rn 30 0.66 15.78 14.82 5.00
198 INT14131 Regulation of HTR1A 34 0.60 9.61 14.74 5.00
199 INT91913 Regulation of GRIN3B 16 0.61 11.48 14.44 5.00
200 INT20071 Positive_regulation of HTR2A 33 0.67 10.89 14 5.00
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