D:Pica

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pChart

Disease Term
Synonyms GEOPHAGIA
Documents 148
Hot Single Events 11
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Pica. They are ordered first by their relevance to Pica and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT296372 Binding of IDUA and ACD 1 0.03 2.72 0.23 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Pica. They are ordered first by their pain relevance and then by number of times they were reported in Pica. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 98.92
2 INT79406 Negative_regulation of Pde4a 20 0.59 25.26 8.35 97.84
3 INT8773 Gene_expression of HBG1 58 0.76 37.6 4.59 97.80
4 INT355896 Regulation of NCBP2 1 0.01 1.76 0 97.74
5 INT68216 Binding of NF1 40 0.48 51.24 4.59 94.52
6 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 93.36
7 INT277256 Negative_regulation of Localization of Satb2 1 0.43 0.59 0.04 89.64
8 INT277258 Localization of Satb2 1 0.81 3.59 0.04 89.64
9 INT277254 Negative_regulation of Satb2 1 0.43 3.26 0.04 89.08
10 INT296385 Binding of IDUA 12 0.39 20.73 0.93 87.04
11 INT7207 Regulation of HBG1 27 0.60 22.1 1.12 86.40
12 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 79.92
13 INT337117 Gene_expression of CLIP1 1 0.13 0.08 0 79.44
14 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 77.68
15 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 77.68
16 INT277259 Regulation of Satb2 1 0.45 0.72 0.03 74.12
17 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 70.00
18 INT163114 Positive_regulation of Gene_expression of GOT1 7 0.24 8.93 0.5 70.00
19 INT4419 Gene_expression of GOT1 20 0.65 22.53 2.53 69.64
20 INT327512 Positive_regulation of Binding of Alad 1 0.27 0.54 0.03 68.28
21 INT327509 Binding of Alad 1 0.20 0.54 0.03 66.92
22 INT113987 Localization of IK 29 0.23 16.73 8.25 59.60
23 INT9188 Localization of HBG1 12 0.75 8.14 2.24 58.24
24 INT97308 Gene_expression of TPO 15 0.65 13.26 2.12 48.44
25 INT279349 Localization of IDUA 7 0.76 4.97 0.07 30.60
26 INT68649 Gene_expression of IL24 9 0.72 6.7 1.7 25.00
27 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 17.40
28 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 14.96
29 INT102353 Positive_regulation of HLA-DQA2 6 0.06 4.07 0.82 9.64
30 INT285398 Positive_regulation of HLA-DRB8 1 0.01 1.11 0 6.84
31 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 5.00
32 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
33 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 5.00
34 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
35 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
36 INT7340 Regulation of Grin1 87 0.62 30.37 57.93 5.00
37 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 5.00
38 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
39 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 5.00
40 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
41 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
42 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 5.00
43 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 5.00
44 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 5.00
45 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51 5.00
46 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 5.00
47 INT8548 Gene_expression of HP 86 0.77 47.62 11.94 5.00
48 INT13240 Gene_expression of TF 94 0.76 57.81 10.99 5.00
49 INT952 Negative_regulation of GHRH 57 0.56 25.3 10.34 5.00
50 INT94784 Binding of ROS1 113 0.40 71.57 10.26 5.00
51 INT57549 Gene_expression of GNPTAB 49 0.65 57.5 9.05 5.00
52 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67 5.00
53 INT7205 Positive_regulation of HBG1 65 0.69 40.35 6.37 5.00
54 INT5490 Binding of CA2 52 0.36 9.73 5.53 5.00
55 INT71418 Binding of CES1 42 0.40 29.78 5.01 5.00
56 INT18011 Positive_regulation of HP 60 0.50 31.88 4.75 5.00
57 INT17110 Gene_expression of PSMD1 60 0.65 19.57 4.69 5.00
58 INT150395 Binding of MEFV 55 0.44 31.18 3.42 5.00
59 INT316829 Negative_regulation of SYNM 4 0.54 3.31 3.32 5.00
60 INT20006 Gene_expression of MT1F 27 0.68 19.55 3.18 5.00
61 INT43907 Binding of CD79A 28 0.48 28.11 3.04 5.00
62 INT45503 Binding of EPO 42 0.48 24.85 2.88 5.00
63 INT134673 Gene_expression of SYNM 16 0.75 2.72 1.62 5.00
64 INT27762 Positive_regulation of Gene_expression of EPO 18 0.70 17.67 1.45 5.00
65 INT29898 Negative_regulation of C6orf25 16 0.29 9.58 1.33 5.00
66 INT38990 Negative_regulation of IDUA 12 0.59 5.04 1.33 5.00
67 INT49978 Localization of Hbb 4 0.39 1.11 1.29 5.00
68 INT225375 Negative_regulation of Cytip 3 0.30 1.63 1.27 5.00
69 INT38989 Gene_expression of IDUA 22 0.78 16.99 1.26 5.00
70 INT132453 Binding of TF 31 0.36 12.98 1.22 5.00
71 INT11063 Negative_regulation of CES1 16 0.53 6.92 1.11 5.00
72 INT69419 Binding of BPPV 5 0.32 7.9 0.7 5.00
73 INT225373 Gene_expression of Cytip 7 0.54 0.68 0.67 5.00
74 INT84250 Positive_regulation of IDUA 8 0.56 15.89 0.62 5.00
75 INT84826 Negative_regulation of ACD 6 0.50 4.02 0.55 5.00
76 INT103638 Negative_regulation of MEFV 7 0.39 5.88 0.54 5.00
77 INT56268 Negative_regulation of Gene_expression of F8a1 2 0.02 1.29 0.52 5.00
78 INT148236 Regulation of GNPTAB 4 0.27 0.87 0.5 5.00
79 INT289719 Gene_expression of BPPV 2 0.51 2.96 0.47 5.00
80 INT353378 Regulation of Cytip 1 0.03 0.83 0.46 5.00
81 INT112215 Binding of Vdr 4 0.31 2.43 0.44 5.00
82 INT20007 Regulation of Gene_expression of MT1F 4 0.07 2.35 0.43 5.00
83 INT90090 Gene_expression of ADO 4 0.58 1.41 0.42 5.00
84 INT38545 Gene_expression of IV 3 0.53 2.89 0.41 5.00
85 INT5223 Negative_regulation of PDP1 8 0.41 1.74 0.37 5.00
86 INT50848 Regulation of ZFP91 5 0.38 2.45 0.35 5.00
87 INT56266 Gene_expression of F8a1 2 0.03 0.69 0.35 5.00
88 INT58409 Negative_regulation of Alad 5 0.43 1.15 0.32 5.00
89 INT222311 Gene_expression of IGKV1-16 4 0.15 4.64 0.3 5.00
90 INT128916 Regulation of CES1 5 0.40 2.95 0.29 5.00
91 INT159113 Binding of MT1F 5 0.42 1.85 0.23 5.00
92 INT84244 Positive_regulation of Gene_expression of IDUA 5 0.70 3.75 0.19 5.00
93 INT353379 Positive_regulation of Nlgn1 1 0.02 0.17 0.17 5.00
94 INT189390 Positive_regulation of MT1F 5 0.08 0.85 0.14 5.00
95 INT120652 Positive_regulation of Alad 2 0.42 1.2 0.12 5.00
96 INT307240 Localization of CYLD 3 0.72 3.09 0.1 5.00
97 INT289720 Positive_regulation of Gene_expression of BPPV 1 0.35 1.63 0.1 5.00
98 INT289718 Positive_regulation of BPPV 1 0.35 1.31 0.1 5.00
99 INT296382 Positive_regulation of SLC11A2 3 0.31 1.49 0.08 5.00
100 INT291143 Binding of PDP1 3 0.34 0.5 0.08 5.00
101 INT162956 Binding of ACD 3 0.32 3.04 0.05 5.00
102 INT244771 Gene_expression of Satb2 4 0.68 1.27 0.03 5.00
103 INT296384 Regulation of SLC40A1 2 0.01 0.83 0.03 5.00
104 INT296386 Localization of DEFA6 3 0.05 0.88 0 5.00
105 INT186639 Gene_expression of SLC11A2 4 0.65 1.91 0 5.00
106 INT327486 Binding of Dpa 1 0.02 1.74 0 5.00
107 INT327511 Negative_regulation of Negative_regulation of Alad 1 0.23 0.29 0 5.00
108 INT296383 Regulation of SLC11A2 1 0.07 0.33 0 5.00
109 INT277257 Binding of Satb2 1 0.37 2.51 0 5.00
110 INT327510 Negative_regulation of Sqstm1 1 0.01 0.41 0 5.00
111 INT327507 Negative_regulation of Localization of CYLD 1 0.05 0.58 0 5.00
112 INT296387 Localization of SLC40A1 2 0.44 0.94 0 5.00
113 INT327508 Localization of CYBRD1 1 0.01 0.24 0 5.00
114 INT277253 Regulation of Localization of Satb2 1 0.45 0.61 0 5.00
115 INT277255 Transcription of Satb2 1 0.69 0.46 0 5.00
116 INT327506 Localization of IGKV1-16 1 0.05 0.52 0 5.00
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