D:Plantar Fasciitis

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Disease Term
Synonyms CHRONIC PLANTAR FASCIITIS, Fasciitis Chronic Plantar, Fasciitis Plantar Chronic, Heel Spur Syndrome, Plantar Fasciitis Chronic
Documents 322
Hot Single Events 14
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Plantar Fasciitis. They are ordered first by their relevance to Plantar Fasciitis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT234113 COL18A1 Negative_regulation of Phosphorylation of VEGFA 1 0.26 0.17 0.16 5.00
2 INT234112 Binding of VEGFA and COL18A1 1 0.21 0.16 0.15 5.00
3 INT269788 Binding of FN1 and TGFB1 1 0.00 0.29 0.1 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Plantar Fasciitis. They are ordered first by their pain relevance and then by number of times they were reported in Plantar Fasciitis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT5590 Negative_regulation of Fos 144 0.59 40.94 81.98 97.20
2 INT118054 Regulation of ARMC9 23 0.34 11.32 1.06 93.28
3 INT2144 Localization of COL7A1 36 0.74 20.92 4.67 91.84
4 INT33857 Negative_regulation of NTS 6 0.42 4.98 3.07 91.68
5 INT82828 Positive_regulation of COMP 45 0.61 35.12 6.2 88.36
6 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 87.44
7 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 87.20
8 INT143127 Positive_regulation of FLT1 44 0.66 21.7 1.92 87.04
9 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37 86.56
10 INT9383 Localization of TRPV1 98 0.81 33.23 46.24 84.08
11 INT116819 Negative_regulation of Localization of TRPV1 3 0.43 1.75 2.71 84.08
12 INT158016 Positive_regulation of VEGFC 7 0.49 6.58 2.18 83.92
13 INT70756 Gene_expression of Adm 28 0.77 13.33 4.22 83.60
14 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 82.68
15 INT626 Localization of CALCA 289 0.81 125.39 221.15 79.20
16 INT8358 Negative_regulation of Localization of CALCA 25 0.59 11.79 21.51 79.20
17 INT118095 Regulation of COMP 7 0.43 9.69 3.33 77.68
18 INT21687 Positive_regulation of ras 143 0.58 97.34 27.31 77.28
19 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 76.12
20 INT86369 Positive_regulation of Gene_expression of PCNA 40 0.67 26.66 3.57 75.20
21 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 75.20
22 INT83200 Positive_regulation of Gene_expression of Nos3 48 0.70 24.75 12.99 75.20
23 INT111594 Positive_regulation of Gene_expression of NOSTRIN 20 0.32 8.69 5 75.20
24 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 74.36
25 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 74.36
26 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57 74.36
27 INT62895 Gene_expression of NOSTRIN 51 0.75 28.8 10.68 74.36
28 INT11937 Localization of Il6 228 0.81 139.83 64.39 74.16
29 INT52722 Localization of RETNLB 54 0.38 48.63 27.98 71.84
30 INT96663 Binding of FABP6 1 0.47 3.17 1.45 71.16
31 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 71.12
32 INT100861 Binding of CRP 179 0.48 175.2 26.45 71.12
33 INT37799 Gene_expression of Apob 13 0.56 10.59 1.36 68.00
34 INT156198 Negative_regulation of Vas1 3 0.30 0.97 1.65 62.40
35 INT55957 Positive_regulation of PRNP 57 0.67 37.87 7.11 61.40
36 INT124220 Binding of Pon1 9 0.47 7.84 0.99 54.64
37 INT3793 Regulation of CEBPZ 59 0.61 20.91 15.83 50.64
38 INT1221 Regulation of SGCG 65 0.60 24.21 22.94 50.28
39 INT102680 Protein_catabolism of COL7A1 49 0.69 34.68 15.78 50.00
40 INT103246 Positive_regulation of Protein_catabolism of COL7A1 8 0.34 8.67 3.03 50.00
41 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 46.80
42 INT240765 Positive_regulation of Pon1 16 0.67 12.06 0.48 33.92
43 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 29.76
44 INT5008 Localization of Calca 204 0.81 80.35 125.16 5.00
45 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 5.00
46 INT5940 Negative_regulation of Avp 236 0.59 67.86 101.2 5.00
47 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
48 INT15913 Negative_regulation of CYP2D6 174 0.59 22.45 70.91 5.00
49 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
50 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
51 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 5.00
52 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 5.00
53 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45 5.00
54 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
55 INT72375 Phosphorylation of Mapk3 87 0.80 43.66 30.27 5.00
56 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72 5.00
57 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 5.00
58 INT7678 Localization of Alb 142 0.81 80.93 22.49 5.00
59 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23 5.00
60 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 5.00
61 INT52457 Gene_expression of ABCB1 129 0.78 38.68 19.88 5.00
62 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 5.00
63 INT12081 Localization of TGFB1 64 0.81 35.4 17.47 5.00
64 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03 5.00
65 INT180497 Binding of MRI1 45 0.42 28.35 14.77 5.00
66 INT27739 Positive_regulation of EGF 49 0.70 28.31 13.68 5.00
67 INT11141 Negative_regulation of Gene_expression of Avp 23 0.59 3.85 12.19 5.00
68 INT398 Localization of AGT 45 0.78 16.97 11.54 5.00
69 INT82829 Gene_expression of COMP 104 0.78 57 9.81 5.00
70 INT2036 Localization of EGF 42 0.77 21.5 9.74 5.00
71 INT173587 Protein_catabolism of COL5A2 59 0.32 32.73 8.96 5.00
72 INT103251 Negative_regulation of Localization of Calca 13 0.43 9.36 8.86 5.00
73 INT82839 Negative_regulation of ABCB1 61 0.59 16.09 8.83 5.00
74 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29 5.00
75 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9 5.00
76 INT78182 Positive_regulation of ACCS 43 0.43 46.39 6.78 5.00
77 INT2513 Binding of Napa 80 0.42 4.29 6.51 5.00
78 INT111545 Phosphorylation of VEGFA 50 0.76 22.19 5.88 5.00
79 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9 5.00
80 INT11064 Positive_regulation of NPR1 24 0.49 14.63 4.78 5.00
81 INT165058 Negative_regulation of MID1 14 0.37 10.82 4.67 5.00
82 INT162258 Negative_regulation of Gene_expression of COMP 35 0.58 19.14 3.55 5.00
83 INT97737 Negative_regulation of Phosphorylation of Mapk3 9 0.57 5.64 3.3 5.00
84 INT57222 Gene_expression of ATF3 22 0.78 54.71 3.28 5.00
85 INT192450 Gene_expression of CLTC 26 0.55 18.82 3.26 5.00
86 INT22375 Localization of PDGFA 21 0.75 15.46 3.25 5.00
87 INT111547 Negative_regulation of Phosphorylation of VEGFA 13 0.42 5.08 3.22 5.00
88 INT279122 Regulation of Gene_expression of COMP 3 0.39 8.82 3.19 5.00
89 INT76430 Gene_expression of SLC1A1 2 0.03 0.77 3.15 5.00
90 INT24821 Binding of VTN 14 0.47 5.83 3 5.00
91 INT200470 Positive_regulation of Gene_expression of COMP 13 0.69 13.73 2.93 5.00
92 INT15557 Regulation of Localization of Alb 13 0.50 5.71 2.91 5.00
93 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5 5.00
94 INT109559 Localization of Napa 16 0.61 1.3 2.42 5.00
95 INT345985 Positive_regulation of Gene_expression of SLC1A1 1 0.01 0.35 2.2 5.00
96 INT68243 Regulation of Gene_expression of IgG 10 0.44 4.93 2.04 5.00
97 INT89240 Gene_expression of VEGFC 23 0.75 15.94 2.03 5.00
98 INT64709 Gene_expression of VTN 11 0.67 11.01 1.97 5.00
99 INT117980 Regulation of Rac1 10 0.45 3.72 1.88 5.00
100 INT234116 Positive_regulation of MID1 9 0.03 3.78 1.61 5.00
101 INT93956 Binding of HBM 20 0.35 8.86 1.48 5.00
102 INT24736 Positive_regulation of SERPINA5 17 0.49 9.55 1.47 5.00
103 INT107541 Positive_regulation of MSD 7 0.43 5.41 1.45 5.00
104 INT118097 Localization of COMP 18 0.70 9.99 1.42 5.00
105 INT12085 Positive_regulation of Localization of TGFB1 7 0.42 4.9 1.4 5.00
106 INT22558 Gene_expression of COL3A1 10 0.78 7.22 1.36 5.00
107 INT199681 Gene_expression of SERPINA5 13 0.36 15.42 1.25 5.00
108 INT97909 Binding of COMP 13 0.37 5.98 1.22 5.00
109 INT124218 Gene_expression of Pon1 9 0.75 19.55 1.19 5.00
110 INT126534 Negative_regulation of ROCK1 18 0.49 14.32 1.13 5.00
111 INT101104 Positive_regulation of Gene_expression of COL1A2 12 0.69 5.87 1.09 5.00
112 INT247970 Regulation of CLTC 8 0.28 5.37 1.06 5.00
113 INT264629 Localization of Rac1 8 0.72 5.7 0.79 5.00
114 INT279130 Negative_regulation of Localization of COMP 5 0.51 3.75 0.69 5.00
115 INT170625 Binding of SERPINA5 8 0.32 8.42 0.69 5.00
116 INT151157 Negative_regulation of SERPINA5 5 0.23 3.68 0.64 5.00
117 INT246642 Binding of CLTCL1 3 0.17 1.32 0.63 5.00
118 INT142005 Gene_expression of COL18A1 6 0.75 4.53 0.62 5.00
119 INT89239 Negative_regulation of Gene_expression of VEGFC 2 0.39 1.11 0.59 5.00
120 INT260422 Positive_regulation of Localization of EGF 3 0.10 1.58 0.56 5.00
121 INT102181 Negative_regulation of CLTC 5 0.37 1.37 0.42 5.00
122 INT297020 Positive_regulation of CLTC 5 0.36 3.38 0.41 5.00
123 INT344613 Negative_regulation of Gene_expression of CLTC 2 0.31 1.19 0.37 5.00
124 INT192448 Positive_regulation of Gene_expression of CLTC 5 0.32 3.01 0.33 5.00
125 INT192346 Positive_regulation of Localization of PDGFA 5 0.37 1.52 0.29 5.00
126 INT264637 Localization of CLDN4 3 0.73 0.85 0.29 5.00
127 INT346132 Regulation of HADH 1 0.01 0.89 0.29 5.00
128 INT192447 Localization of CLTC 6 0.44 2.32 0.29 5.00
129 INT111676 Phosphorylation of MYH14 5 0.48 2.14 0.28 5.00
130 INT332658 Gene_expression of Laptm4a 1 0.01 0.48 0.25 5.00
131 INT231466 Binding of COL18A1 2 0.25 1.19 0.18 5.00
132 INT332665 Negative_regulation of ALDH1B1 1 0.02 0.1 0.15 5.00
133 INT170624 Localization of SERPINA5 3 0.40 0.79 0.12 5.00
134 INT70544 Negative_regulation of Fbrs 5 0.37 4.15 0.09 5.00
135 INT192449 Binding of CLTC 5 0.23 3.57 0.09 5.00
136 INT332664 Positive_regulation of GUCY2D 1 0.01 0.13 0.07 5.00
137 INT241221 Localization of MBS1 1 0.40 0.09 0.04 5.00
138 INT234117 Positive_regulation of Binding of MRI1 2 0.44 0.19 0 5.00
139 INT188124 Gene_expression of Sbds 6 0.24 0.68 0 5.00
140 INT344614 Protein_catabolism of CLTC 1 0.56 0.77 0 5.00
141 INT188896 Gene_expression of PAGE1 4 0.13 1.14 0 5.00
142 INT297019 Regulation of Gene_expression of CLTC 2 0.37 0.8 0 5.00
143 INT241220 Gene_expression of MBS1 2 0.36 0.38 0 5.00
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