D:Plasmodium Infection

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Blackwater Fever, Disease Due To Plasmodiidae, Fever Marsh, FEVER REMITTENT, INFECTION PLASMODIUM, Infections Plasmodium, Malaria, Malarial Fever, Marsh Fever, Paludism, PLASMODIOSIS
Documents 21
Hot Single Events 28
Hot Interactions 5

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Plasmodium Infection. They are ordered first by their relevance to Plasmodium Infection and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT278398 Hps5 Positive_regulation of Nlrp3 1 0.26 1.38 0.16 99.62
2 INT278378 Hps5 Positive_regulation of Gene_expression of S100a8 1 0.00 0.42 0.09 93.72
3 INT278368 Regulation of Binding of Il1 and Hps5 1 0.02 0.44 0.09 87.44
4 INT278371 Binding of Il1 and Hps5 1 0.02 0.44 0.09 87.00
5 INT278403 Hps5 Positive_regulation of Il1 1 0.04 1.48 0.24 83.80
6 INT278390 Hps5 Positive_regulation of Darc 1 0.01 0.49 0.22 74.80
7 INT278391 Hps5 Positive_regulation of Hrec 1 0.01 0.5 0.22 74.80
8 INT278383 Pigb Regulation of Il1 1 0.00 0.2 0 53.36
9 INT278409 Pigb Regulation of Hps5 1 0.00 0.2 0 53.36
10 INT278367 Hps5 Positive_regulation of Gene_expression of Ros1 1 0.01 0 0 48.24
11 INT278408 Hps5 Positive_regulation of Localization of Ctsb 1 0.05 0.11 0.03 46.56
12 INT278373 Myd88 Regulation of Phosphorylation of Syk 1 0.15 0.35 0.15 45.44
13 INT278394 Myd88 Regulation of Phosphorylation of Hps5 1 0.11 0.35 0.15 45.44
14 INT278389 Binding of Casp1 and Il1 2 0.09 0.82 0.36 37.72
15 INT278392 Syk Regulation of Positive_regulation of Ctsb 1 0.06 0 0 33.28
16 INT278388 Msu Positive_regulation of Phosphorylation of Lyn 1 0.17 0.12 0 32.84
17 INT278396 Msu Positive_regulation of Phosphorylation of Syk 1 0.25 0.27 0 28.76
18 INT278381 Binding of Akt1 and Pycard 1 0.00 0 0 22.08
19 INT278372 Binding of Syk and Pycard 1 0.06 0 0 22.08
20 INT278397 Hps5 Positive_regulation of Tlr9 1 0.15 0.21 0.11 17.76
21 INT278382 Binding of Syk and Nlrp3 1 0.24 0 0 16.44
22 INT278385 Binding of Pycard and Nlrp3 1 0.06 0 0 14.76
23 INT278395 Binding of Pycard and Hps5 1 0.04 0 0 11.28
24 INT278407 Hps5 Positive_regulation of Gene_expression of Darc 1 0.01 0.22 0.19 7.20
25 INT278379 Binding of Pstpip1 and Mefv 3 0.03 2.02 0.48 5.76
26 INT278376 Negative_regulation of Casp1 Negative_regulation of Hps5 1 0.05 0.05 0.08 5.00
27 INT278404 Syk Positive_regulation of Mapk1 1 0.13 0 0 5.00
28 INT278369 Ctsb Positive_regulation of Casp1 1 0.03 0 0 5.00
29 INT278374 Msu Positive_regulation of Phosphorylation of Gopc 1 0.14 0.21 0 5.00
30 INT278384 Il1 Negative_regulation of Ctsb 1 0.01 0.12 0 5.00
31 INT278400 Negative_regulation of Syk Negative_regulation of Positive_regulation of Hps5 1 0.16 0 0 5.00
32 INT278370 Gopc Positive_regulation of Positive_regulation of Msu 1 0.10 0.22 0 5.00
33 INT278401 Syk Regulation of Positive_regulation of Hps5 1 0.19 0 0 5.00
34 INT278410 Gopc Positive_regulation of Phosphorylation of Syk 1 0.10 0.23 0 5.00
35 INT278406 Il1 Regulation of Gene_expression of Hps5 1 0.03 0 0 5.00
36 INT278387 Syk Regulation of Positive_regulation of Il1 1 0.06 0 0 5.00
37 INT278399 Syk Positive_regulation of Localization of Ctsb 1 0.09 0.28 0 5.00
38 INT278405 Tlr4 Positive_regulation of Syk 1 0.06 0 0 5.00
39 INT278375 Il1 Negative_regulation of Ctsr 1 0.01 0.12 0 5.00
40 INT278402 Akt1 Regulation of Il1 1 0.00 0 0 5.00
41 INT278386 Hps5 Positive_regulation of Positive_regulation of Msu 1 0.18 0.22 0 5.00
42 INT278380 Syk Positive_regulation of Pik3r1 1 0.13 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Plasmodium Infection. They are ordered first by their pain relevance and then by number of times they were reported in Plasmodium Infection. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT278340 Gene_expression of Syk 7 0.51 4.92 2.09 100.00
2 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81 100.00
3 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75 100.00
4 INT97979 Regulation of Hrec 10 0.02 5.06 2.38 99.68
5 INT25607 Binding of Il1 82 0.47 64.4 23.9 99.60
6 INT157840 Regulation of Darc 4 0.02 2.35 1.47 99.12
7 INT278345 Positive_regulation of Positive_regulation of Ctsb 1 0.09 0.82 0.03 98.80
8 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 98.64
9 INT99020 Gene_expression of Nlrp3 23 0.75 18.86 4.4 98.24
10 INT219135 Positive_regulation of Gene_expression of Nlrp3 4 0.49 3.52 0.93 98.24
11 INT73479 Positive_regulation of Hrec 21 0.04 16.16 6.87 98.08
12 INT278353 Regulation of Regulation of Nlrp3 1 0.23 0.85 0.1 97.52
13 INT278350 Regulation of Nlrp3 3 0.38 2.8 0.95 97.52
14 INT36221 Positive_regulation of Nlrp3 25 0.68 19.7 4.5 96.76
15 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 96.40
16 INT126164 Positive_regulation of Ctsb 15 0.49 3.34 0.63 96.40
17 INT25610 Positive_regulation of Gene_expression of Il1 136 0.67 104.43 43.86 95.76
18 INT278360 Binding of Hps5 1 0.23 1.69 0.31 94.48
19 INT278331 Localization of Hps5 3 0.34 4.14 0.34 93.96
20 INT278324 Localization of Pymr 1 0.01 1.01 0.23 93.96
21 INT152730 Positive_regulation of S100a8 48 0.68 47.67 15.4 93.44
22 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 91.60
23 INT89661 Gene_expression of Hrec 102 0.21 69.91 39.57 91.52
24 INT278318 Gene_expression of Hps5 10 0.37 4.24 1.27 91.28
25 INT168448 Localization of Nlrp3 5 0.73 3.75 0.58 90.84
26 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 90.24
27 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 90.24
28 INT20129 Regulation of Il1 53 0.53 44.14 19.89 87.44
29 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 79.60
30 INT32795 Positive_regulation of Hypism 17 0.15 20.16 1.73 78.40
31 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 77.52
32 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 77.52
33 INT89660 Positive_regulation of Gene_expression of Hrec 15 0.17 12.06 7.37 76.48
34 INT278363 Binding of Syk 1 0.32 0.3 0.04 75.60
35 INT2947 Regulation of TFPI 10 0.44 5.81 4.86 75.00
36 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 65.12
37 INT278319 Positive_regulation of Gene_expression of Hps5 1 0.24 0.56 0.25 63.44
38 INT18522 Positive_regulation of Gene_expression of IFNA1 248 0.67 160.85 44.87 51.80
39 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 50.20
40 INT278321 Localization of Ctsb 1 0.14 0.67 0.03 46.56
41 INT278344 Phosphorylation of Hps5 1 0.39 0.57 0.15 45.44
42 INT275937 Phosphorylation of Syk 3 0.54 1.67 0.15 45.44
43 INT17886 Negative_regulation of Il1 95 0.57 70.91 31.25 42.88
44 INT278362 Negative_regulation of Hps5 2 0.21 15.71 4.44 42.88
45 INT191589 Gene_expression of Msu 9 0.46 7.08 1.33 42.20
46 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 41.24
47 INT146945 Positive_regulation of Lyn 6 0.49 2.81 2.25 39.28
48 INT199076 Positive_regulation of Syk 3 0.31 0.12 0.07 39.12
49 INT261820 Phosphorylation of Lyn 5 0.30 1.41 0.2 31.80
50 INT92260 Binding of Nlrp3 14 0.46 8.94 2.13 16.12
51 INT216978 Binding of Pycard 6 0.25 2.93 0.22 16.12
52 INT278333 Phosphorylation of Pycard 1 0.11 0 0 8.76
53 INT163165 Phosphorylation of Mefv 2 0.32 0.86 0.26 8.60
54 INT278329 Phosphorylation of Pstpip1 1 0.35 0 0 6.56
55 INT165773 Gene_expression of Darc 37 0.75 22.28 14.84 6.48
56 INT278351 Binding of Pstpip1 1 0.20 0 0 5.76
57 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
58 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
59 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32 5.00
60 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 5.00
61 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 5.00
62 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42 5.00
63 INT173693 Localization of Gopc 249 0.65 70.49 38.81 5.00
64 INT117112 Negative_regulation of Mapk1 87 0.56 40.34 31.18 5.00
65 INT172458 Regulation of Gopc 155 0.53 62.57 24.86 5.00
66 INT112029 Positive_regulation of Pik3r1 90 0.67 38.76 20.95 5.00
67 INT111531 Negative_regulation of Phosphorylation of Mapk14 37 0.50 20 17.68 5.00
68 INT96911 Positive_regulation of Phosphorylation of Mapk14 46 0.70 43.03 15.15 5.00
69 INT114420 Negative_regulation of Pik3r1 67 0.54 34.86 12.82 5.00
70 INT96915 Phosphorylation of Mapk8 73 0.81 40.69 11.44 5.00
71 INT69035 Positive_regulation of Casp1 43 0.69 25.18 10.67 5.00
72 INT25608 Regulation of Gene_expression of Il1 37 0.44 27.76 10.1 5.00
73 INT178306 Negative_regulation of Gene_expression of Gopc 71 0.37 26.43 9.74 5.00
74 INT175526 Phosphorylation of Gopc 73 0.53 21.08 7.86 5.00
75 INT5409 Negative_regulation of G6pd 33 0.57 29.21 7.64 5.00
76 INT69033 Negative_regulation of Casp1 21 0.58 13.15 7.52 5.00
77 INT45753 Localization of CD40LG 45 0.79 32.31 5.28 5.00
78 INT175524 Negative_regulation of Phosphorylation of Gopc 14 0.20 2.74 2.96 5.00
79 INT123705 Gene_expression of SMARCB1 40 0.73 19.47 2.2 5.00
80 INT191862 Phosphorylation of Tlr4 17 0.79 6.89 1.74 5.00
81 INT126759 Negative_regulation of Nlrp3 5 0.41 2.95 1.58 5.00
82 INT220273 Positive_regulation of Msu 9 0.33 5.83 1.41 5.00
83 INT156326 Positive_regulation of SMARCB1 20 0.67 8.77 0.97 5.00
84 INT275940 Negative_regulation of Syk 3 0.39 2.08 0.95 5.00
85 INT278334 Negative_regulation of Hsp90ab1 3 0.30 4.34 0.68 5.00
86 INT278341 Positive_regulation of Hps5 8 0.38 5.47 0.62 5.00
87 INT219136 Positive_regulation of Positive_regulation of Nlrp3 3 0.49 2.61 0.58 5.00
88 INT278316 Regulation of Positive_regulation of Nlrp3 2 0.39 0.83 0.47 5.00
89 INT254317 Negative_regulation of Pycard 5 0.42 3.13 0.45 5.00
90 INT73979 Gene_expression of Hsp90ab1 6 0.61 3.68 0.43 5.00
91 INT278328 Negative_regulation of Gene_expression of Hps5 1 0.20 1.1 0.39 5.00
92 INT51242 Localization of Umod 3 0.80 0.96 0.38 5.00
93 INT145457 Positive_regulation of Clec7a 2 0.04 0.17 0.34 5.00
94 INT61611 Positive_regulation of ANC 17 0.41 4.43 0.31 5.00
95 INT235549 Gene_expression of Ctsb 19 0.58 8.61 0.2 5.00
96 INT278361 Positive_regulation of Gene_expression of Lyn 6 0.41 0.63 0.15 5.00
97 INT262796 Positive_regulation of Pycard 12 0.22 6.5 0.14 5.00
98 INT219359 Localization of SMARCB1 7 0.66 4.17 0.09 5.00
99 INT278337 Positive_regulation of Pigb 1 0.01 0.27 0.08 5.00
100 INT278317 Negative_regulation of Gene_expression of Hsp90ab1 1 0.07 0.05 0.08 5.00
101 INT278359 Negative_regulation of Nlrc4 1 0.25 0.15 0.03 5.00
102 INT278358 Negative_regulation of Nlrx1 1 0.01 0.15 0.03 5.00
103 INT169032 Positive_regulation of Nlrx1 2 0.14 0.28 0 5.00
104 INT278342 Positive_regulation of Localization of Ctsb 1 0.09 0 0 5.00
105 INT209438 Phosphorylation of Stam 2 0.09 0.45 0 5.00
106 INT174983 Regulation of HTN3 1 0.00 0.63 0 5.00
107 INT278354 Positive_regulation of Phosphorylation of Syk 1 0.31 0.23 0 5.00
108 INT331308 Gene_expression of PLEKHG4 1 0.15 0.81 0 5.00
109 INT278355 Phosphorylation of Scr 1 0.61 0.19 0 5.00
110 INT278323 Positive_regulation of Phosphorylation of Lyn 1 0.22 0 0 5.00
111 INT278322 Negative_regulation of Localization of Lyn 1 0.20 0.11 0 5.00
112 INT278348 Positive_regulation of Gene_expression of Syk 1 0.33 0 0 5.00
113 INT278325 Negative_regulation of Positive_regulation of Ctsb 1 0.08 0 0 5.00
114 INT278326 Regulation of Positive_regulation of Syk 1 0.18 0 0 5.00
115 INT278356 Localization of Lyn 1 0.35 0.11 0 5.00
116 INT278336 Negative_regulation of Phosphorylation of Hps5 1 0.21 0 0 5.00
117 INT331307 Negative_regulation of Gene_expression of PLEKHG4 1 0.10 0.87 0 5.00
118 INT278315 Phosphorylation of Msu 1 0.41 0.21 0 5.00
119 INT278346 Positive_regulation of Negative_regulation of Syk 1 0.33 0 0 5.00
120 INT278339 Negative_regulation of Positive_regulation of Hps5 1 0.20 0 0 5.00
121 INT278352 Regulation of Positive_regulation of Ctsb 1 0.08 0 0 5.00
122 INT278332 Regulation of Ctsb 3 0.22 2.06 0 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox