D:Pleomorphic Adenoma

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Disease Term
Synonyms Adenomas Pleomorphic, Chondroid Syringoma, Chondroid Syringomas, MIXED SALIVARY GLAND TUMOR, Pleomorphic Adenomas, Salivary Gland Tumor Mixed, Syringoma Chondroid, Syringomas Chondroid
Documents 77
Hot Single Events 10
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Pleomorphic Adenoma. They are ordered first by their relevance to Pleomorphic Adenoma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT217139 Binding of MIR103A2 and MIR107 1 0.06 0.83 0 77.80
2 INT217136 Negative_regulation of MIR221 Negative_regulation of Gene_expression of KIT 1 0.18 0.74 0 58.40
3 INT217138 Negative_regulation of MIR222 Negative_regulation of Gene_expression of KIT 1 0.16 0.74 0 58.40
4 INT217144 MIR21 Negative_regulation of TPM1 1 0.06 1.03 0 44.08
5 INT217148 MIR21 Regulation of BCL2 1 0.32 0.98 0.03 19.68
6 INT292882 Binding of S100A12 and TP63 1 0.06 0.51 0 5.00
7 INT217145 Gene_expression of MIR26B Negative_regulation of Gene_expression of MCL1 1 0.10 1 0 5.00
8 INT217143 MIR29A Regulation of Gene_expression of MCL1 1 0.24 1 0 5.00
9 INT217150 MIR16-2 Regulation of BCL2 2 0.09 1.89 0 5.00
10 INT217149 MIR20A Regulation of Gene_expression of E2F1 1 0.19 0.86 0 5.00
11 INT217137 MIR15B Regulation of BCL2 2 0.15 1.88 0 5.00
12 INT217141 Binding of BCL2 and MIR15B 1 0.21 1.26 0 5.00
13 INT217151 Gene_expression of MIR98 Negative_regulation of HMGA2 1 0.24 1.08 0 5.00
14 INT242102 Nkx2-1 Regulation of Gene_expression of Ttf1 1 0.00 1.55 0 5.00
15 INT217146 Binding of BCL2 and MIR16-2 1 0.12 1.25 0 5.00
16 INT217147 MIR17 Regulation of Gene_expression of E2F1 1 0.20 0.85 0 5.00
17 INT217142 MIR98 Regulation of Gene_expression of HMGA2 1 0.40 2.22 0 5.00
18 INT217140 MIR223 Regulation of CEBPA 1 0.17 0.59 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Pleomorphic Adenoma. They are ordered first by their pain relevance and then by number of times they were reported in Pleomorphic Adenoma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT8571 Gene_expression of B3GAT1 54 0.75 36.85 15.98 100.00
2 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 99.70
3 INT74019 Regulation of TSC1 27 0.35 23.61 0.79 96.24
4 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 95.32
5 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 94.64
6 INT48792 Regulation of ERBB2 48 0.57 36.56 1.8 93.08
7 INT217168 Gene_expression of MIR21 30 0.55 30.86 0.62 83.60
8 INT217156 Positive_regulation of Gene_expression of MIR21 9 0.49 16.04 0.38 82.80
9 INT217186 Gene_expression of MIR155 26 0.48 29.45 7.92 82.36
10 INT217208 Positive_regulation of Gene_expression of MIR155 3 0.31 2.7 0.29 82.36
11 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34 79.28
12 INT5136 Negative_regulation of PDYN 71 0.59 11.22 51.14 79.28
13 INT1154 Negative_regulation of CCK 24 0.59 9.3 15.32 79.28
14 INT14681 Negative_regulation of GCG 31 0.57 13.55 4.98 79.28
15 INT217154 Gene_expression of MIR103A2 2 0.18 1.42 0 78.36
16 INT217207 Gene_expression of MIR107 1 0.48 1.37 0 78.36
17 INT217228 Binding of MIR103A2 1 0.08 0.83 0 77.80
18 INT217177 Binding of MIR107 1 0.22 0.82 0 77.32
19 INT217167 Negative_regulation of Gene_expression of MIR155 4 0.23 3.43 0.91 76.20
20 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 71.76
21 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 70.56
22 INT217162 Negative_regulation of MIR21 7 0.30 7.01 0.34 64.16
23 INT186998 Negative_regulation of Gene_expression of KIT 20 0.43 16.77 0.46 58.40
24 INT217221 Negative_regulation of MIR222 2 0.35 1.7 0 58.40
25 INT217236 Negative_regulation of MIR221 3 0.38 1.99 0 58.40
26 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 55.12
27 INT165054 Gene_expression of MIR146A 45 0.58 82.87 28.82 50.32
28 INT217182 Gene_expression of MIR221 4 0.58 9.33 0.27 49.96
29 INT217189 Gene_expression of MIR222 5 0.46 4.58 0.12 49.48
30 INT14682 Regulation of B3GAT1 9 0.54 3.9 4.06 48.56
31 INT11920 Regulation of ENO2 18 0.55 11.51 2.89 47.28
32 INT109327 Negative_regulation of KIT 42 0.57 43.2 2.15 42.60
33 INT217234 Negative_regulation of Transcription of KIT 1 0.24 0.57 0 42.60
34 INT192957 Transcription of KIT 5 0.69 2.19 0.23 42.28
35 INT217178 Regulation of MIR21 2 0.17 3.02 0.11 39.28
36 INT217224 Regulation of TPM1 2 0.34 2.9 0.07 39.28
37 INT124944 Regulation of KIT 15 0.60 11.84 0.24 38.00
38 INT217230 Positive_regulation of MIR221 4 0.52 3.82 0 31.00
39 INT217165 Positive_regulation of MIR222 3 0.47 2.94 0 31.00
40 INT217220 Positive_regulation of MIR181B2 1 0.10 0.65 0 31.00
41 INT111477 Gene_expression of KRT7 90 0.74 86.76 4.07 13.96
42 INT217217 Negative_regulation of MIR128-2 1 0.19 0.89 0 11.84
43 INT217196 Negative_regulation of MIR181A2 1 0.07 0.89 0 11.48
44 INT217176 Negative_regulation of MIR181B2 1 0.06 0.89 0 11.08
45 INT217192 Negative_regulation of MIR181C 1 0.17 0.89 0 10.56
46 INT164735 Gene_expression of MIR29A 4 0.75 2.98 0.24 7.12
47 INT217120 Gene_expression of Mir181a-2 3 0.58 2.52 0 7.12
48 INT217231 Regulation of Positive_regulation of MIR29A 1 0.26 0.94 0 6.68
49 INT217121 Positive_regulation of Mir181a-2 1 0.10 0.88 0 6.68
50 INT217155 Positive_regulation of MIR29A 2 0.45 0.88 0 6.68
51 INT217117 Regulation of Positive_regulation of Mir181a-2 1 0.09 0.94 0 6.68
52 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 5.00
53 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
54 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
55 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
56 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 5.00
57 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
58 INT20420 Gene_expression of MYC 99 0.75 49.32 14.36 5.00
59 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 5.00
60 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27 5.00
61 INT84685 Regulation of BCL2 67 0.60 72.96 6.65 5.00
62 INT16688 Positive_regulation of Cndp2 11 0.49 1.12 5.86 5.00
63 INT164587 Gene_expression of MCL1 94 0.75 124.05 5.39 5.00
64 INT80038 Positive_regulation of Gene_expression of MYC 24 0.67 13.93 5.17 5.00
65 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07 5.00
66 INT95652 Gene_expression of Krt20 54 0.61 53.69 3.31 5.00
67 INT163283 Gene_expression of E2F1 21 0.71 3.77 2.26 5.00
68 INT21611 Negative_regulation of RASGRP1 20 0.35 11.76 2.15 5.00
69 INT164583 Negative_regulation of Gene_expression of MCL1 19 0.56 22.45 1.94 5.00
70 INT169862 Regulation of NPC1 13 0.53 13.61 1.84 5.00
71 INT43637 Positive_regulation of AXL 11 0.58 11.71 1.59 5.00
72 INT166021 Positive_regulation of MCL1 36 0.67 62.97 1.44 5.00
73 INT8068 Gene_expression of RASGRP1 29 0.54 15.1 1.37 5.00
74 INT8063 Regulation of RASGRP1 15 0.36 9.15 1.3 5.00
75 INT171512 Gene_expression of RARS 4 0.45 2.56 1.17 5.00
76 INT93168 Gene_expression of Ttf1 24 0.63 17.18 1.14 5.00
77 INT217157 Gene_expression of MIR34A 9 0.58 9.36 0.77 5.00
78 INT88987 Gene_expression of HMGA2 8 0.77 10.46 0.64 5.00
79 INT217160 Gene_expression of MIR223 5 0.44 2.41 0.48 5.00
80 INT175423 Positive_regulation of TSC1 25 0.36 21.81 0.45 5.00
81 INT143703 Gene_expression of MIR196A2 3 0.75 2.52 0.32 5.00
82 INT217210 Negative_regulation of Gene_expression of MIR143 2 0.27 2.29 0.3 5.00
83 INT217166 Gene_expression of MIR17HG 7 0.58 7.09 0.29 5.00
84 INT217164 Gene_expression of MIR143 2 0.37 2.27 0.29 5.00
85 INT217152 Gene_expression of MIR145 4 0.43 5.15 0.29 5.00
86 INT164734 Positive_regulation of Gene_expression of MIR29A 3 0.67 2.1 0.24 5.00
87 INT217214 Negative_regulation of MIR17 2 0.24 1.37 0.2 5.00
88 INT217124 Positive_regulation of Mirlet7a-1 3 0.08 1.78 0.16 5.00
89 INT244657 Regulation of Lch 3 0.40 6.63 0.13 5.00
90 INT213951 Gene_expression of MIR301A 2 0.36 2.34 0.11 5.00
91 INT217180 Positive_regulation of Gene_expression of MIR17HG 5 0.42 4.75 0.11 5.00
92 INT311689 Positive_regulation of 119L04aR 2 0.01 1.09 0.1 5.00
93 INT186056 Binding of MKI67 6 0.48 4.44 0.1 5.00
94 INT217205 Regulation of MIR143 1 0.17 1.92 0.09 5.00
95 INT217170 Gene_expression of MIR15A 4 0.75 8.17 0.09 5.00
96 INT217197 Gene_expression of MIR16-1 5 0.45 3.93 0.09 5.00
97 INT217173 Negative_regulation of MIR15B 6 0.42 4.37 0.08 5.00
98 INT217184 Negative_regulation of MIR145 5 0.31 4.04 0.08 5.00
99 INT242098 Negative_regulation of Ttf1 2 0.04 2.52 0.07 5.00
100 INT217212 Negative_regulation of MIR20A 1 0.24 0.82 0.05 5.00
101 INT217174 Regulation of MIR133B 2 0.21 1.68 0.05 5.00
102 INT217235 Binding of MIR155 2 0.20 1.9 0.04 5.00
103 INT217215 Negative_regulation of MIR10B 1 0.16 0.9 0.04 5.00
104 INT217213 Binding of MIR21 1 0.23 0.89 0.04 5.00
105 INT217227 Regulation of MIR135B 1 0.19 0.96 0.03 5.00
106 INT93169 Binding of Ttf1 3 0.30 2.04 0.03 5.00
107 INT217211 Negative_regulation of MIR143 2 0.27 1.71 0.03 5.00
108 INT217161 Regulation of MIR183 1 0.32 0.96 0.03 5.00
109 INT311690 Regulation of 119L04aR 1 0.01 0.39 0.03 5.00
110 INT217153 Gene_expression of MIR31 1 0.39 0.93 0.03 5.00
111 INT217158 Regulation of MIR145 2 0.32 1.15 0.03 5.00
112 INT217193 Negative_regulation of Negative_regulation of AXL 1 0.01 1.12 0 5.00
113 INT217204 Regulation of MIR96 2 0.29 1.25 0 5.00
114 INT217159 Localization of AIMP1 1 0.49 1.19 0 5.00
115 INT217172 Localization of MIR301A 1 0.35 1.16 0 5.00
116 INT217125 Negative_regulation of Gene_expression of Dld 1 0.41 0.72 0 5.00
117 INT217222 Positive_regulation of Gene_expression of MIR107 1 0.31 0.54 0 5.00
118 INT217202 Positive_regulation of Gene_expression of MIR26B 1 0.11 0.94 0 5.00
119 INT217185 Localization of MIR376A1 1 0.09 1.16 0 5.00
120 INT217218 Positive_regulation of Gene_expression of TCL1A 1 0.43 0.98 0 5.00
121 INT217169 Positive_regulation of Transcription of E2F1 1 0.46 0.79 0 5.00
122 INT217232 Positive_regulation of MIR107 1 0.43 0.49 0 5.00
123 INT217181 Negative_regulation of Gene_expression of MIR98 1 0.26 1.08 0 5.00
124 INT217203 Positive_regulation of Phosphorylation of PROC 1 0.01 1.96 0 5.00
125 INT242099 Binding of Nkx2-1 1 0.02 1.15 0 5.00
126 INT217122 Gene_expression of Dld 1 0.65 0.71 0 5.00
127 INT217216 Gene_expression of MIR98 1 0.47 1.07 0 5.00
128 INT217198 Positive_regulation of MIR17HG 1 0.14 1 0 5.00
129 INT217195 Negative_regulation of HMGA2 1 0.55 3.54 0 5.00
130 INT217219 Binding of MIRLET7A3 1 0.15 1.01 0 5.00
131 INT311687 Binding of 119L04aR 2 0.01 0.61 0 5.00
132 INT217118 Positive_regulation of Gene_expression of Colec10 1 0.49 0.93 0 5.00
133 INT217190 Localization of MIR15B 1 0.42 1.88 0 5.00
134 INT292884 Positive_regulation of Binding of MKI67 1 0.06 0.52 0 5.00
135 INT217163 Gene_expression of MIRLET7A2 1 0.17 1.21 0 5.00
136 INT212047 Phosphorylation of PROC 2 0.13 1.41 0 5.00
137 INT217200 Positive_regulation of Gene_expression of MIR98 1 0.28 1.07 0 5.00
138 INT217229 Regulation of MIR31 1 0.29 0.95 0 5.00
139 INT217175 Regulation of MIR223 1 0.29 0.54 0 5.00
140 INT217201 Gene_expression of MIR26B 1 0.17 0.94 0 5.00
141 INT217191 Localization of MIR221 1 0.56 1.16 0 5.00
142 INT217199 Gene_expression of TCL1A 1 0.66 1.92 0 5.00
143 INT217226 Positive_regulation of MIR16-1 1 0.40 1.17 0 5.00
144 INT217194 Localization of MIR16-2 1 0.24 1.88 0 5.00
145 INT217209 Regulation of MIRLET7A3 1 0.25 1.03 0 5.00
146 INT217223 Positive_regulation of MIR15A 1 0.25 1.16 0 5.00
147 INT217179 Negative_regulation of AXL 2 0.01 1.9 0 5.00
148 INT217123 Gene_expression of Colec10 1 0.65 0.93 0 5.00
149 INT217206 Regulation of Gene_expression of TCL1A 1 0.39 0.94 0 5.00
150 INT217225 Negative_regulation of Negative_regulation of HMGA2 1 0.55 2.4 0 5.00
151 INT217171 Negative_regulation of Gene_expression of MIR26B 1 0.10 0.94 0 5.00
152 INT311688 Gene_expression of 119L04aR 2 0.02 0.16 0 5.00
153 INT217233 Transcription of E2F1 1 0.48 0.78 0 5.00
154 INT217188 Negative_regulation of MIR26B 1 0.13 0.94 0 5.00
155 INT217187 Regulation of CEBPA 1 0.44 0.54 0 5.00
156 INT217119 Positive_regulation of Gene_expression of Mir181a-2 1 0.10 0.95 0 5.00
157 INT217183 Gene_expression of MIR376A1 1 0.09 1.16 0 5.00
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