D:Pleural Disease

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pChart

Disease Term
Synonyms Disease Of Pleura, Disease Pleural, Diseases Pleural, Disorder Of Pleura Pleural Cavity, Pleural Diseases, Pleural Disorder
Documents 79
Hot Single Events 10
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Pleural Disease. They are ordered first by their relevance to Pleural Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT263081 IFN1@ Regulation of CXCL10 1 0.07 0.15 0.15 5.00
2 INT242015 Binding of Mdm2 and Trp53 3 0.16 5.74 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Pleural Disease. They are ordered first by their pain relevance and then by number of times they were reported in Pleural Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT8103 Binding of TP53 46 0.44 40.2 2.96 97.32
2 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 92.48
3 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 92.00
4 INT37541 Gene_expression of SPP1 113 0.77 68.54 11.35 89.64
5 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 88.96
6 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 82.40
7 INT49325 Gene_expression of Cd34 102 0.78 82.75 8.97 82.40
8 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 82.32
9 INT70273 Gene_expression of CALB2 9 0.75 7.85 2.54 81.20
10 INT159190 Gene_expression of KRT5 31 0.65 26.67 0.56 80.60
11 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 79.40
12 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 68.04
13 INT28312 Gene_expression of ABCA1 85 0.72 37.69 9.27 66.56
14 INT76065 Localization of MSLN 6 0.68 5.93 0.34 61.32
15 INT263804 Localization of MSLNL 3 0.55 2.13 0.14 58.60
16 INT719 Negative_regulation of SGCG 96 0.57 47.91 30.22 56.64
17 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 50.00
18 INT10833 Regulation of Gene_expression of IL8 68 0.62 38.74 18.46 50.00
19 INT88934 Regulation of SPP1 9 0.54 6.94 1.47 50.00
20 INT237842 Negative_regulation of TPCN1 3 0.06 0.86 0.09 50.00
21 INT280499 Regulation of SUPV3L1 1 0.01 1.6 0.09 50.00
22 INT280498 Positive_regulation of SUPV3L1 1 0.01 2.73 0.04 50.00
23 INT62710 Gene_expression of HGF 160 0.78 88.27 26.14 44.92
24 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 44.72
25 INT200219 Positive_regulation of VHL 18 0.50 15.38 0.67 44.72
26 INT99550 Regulation of FLNA 51 0.54 27.88 2.58 44.04
27 INT3364 Binding of SGCG 87 0.47 31.93 17.24 41.52
28 INT28238 Positive_regulation of Hrct1 5 0.38 3.66 0.5 36.16
29 INT175449 Gene_expression of Sftpd 30 0.55 25.7 3.15 36.08
30 INT189445 Positive_regulation of MSLN 20 0.37 3.5 0.3 19.32
31 INT17056 Gene_expression of DLD 37 0.57 13.15 5.47 17.72
32 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 5.00
33 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
34 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 5.00
35 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 5.00
36 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 5.00
37 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74 5.00
38 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 5.00
39 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81 5.00
40 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 5.00
41 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 5.00
42 INT5199 Gene_expression of Fosl1 44 0.78 8.66 24.8 5.00
43 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23 5.00
44 INT125312 Positive_regulation of COPD 134 0.59 162.55 20.27 5.00
45 INT70970 Binding of COPD 144 0.42 180.34 18.29 5.00
46 INT75531 Regulation of MAPK1 70 0.61 34.39 15.42 5.00
47 INT112003 Localization of ROS1 94 0.73 66.32 12.16 5.00
48 INT60198 Binding of JUN 54 0.48 11.56 10.27 5.00
49 INT170333 Binding of IFN1@ 68 0.47 49.01 9.72 5.00
50 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 5.00
51 INT104396 Positive_regulation of Positive_regulation of Akt1 44 0.55 14.78 8.69 5.00
52 INT114882 Positive_regulation of Gene_expression of Akt1 45 0.69 21.29 6.06 5.00
53 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65 5.00
54 INT92234 Regulation of CXCL10 15 0.42 8.37 5.09 5.00
55 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68 5.00
56 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21 5.00
57 INT7904 Positive_regulation of Gene_expression of Fosl1 5 0.61 1.39 2.96 5.00
58 INT188047 Positive_regulation of Wnt2 51 0.58 31.41 2.94 5.00
59 INT7142 Positive_regulation of DLD 22 0.60 7.69 2.76 5.00
60 INT16463 Gene_expression of FTH1 15 0.65 6.28 2.66 5.00
61 INT212571 Negative_regulation of Ptv1 2 0.24 2.98 2.05 5.00
62 INT182899 Transcription of IFN1@ 17 0.69 4.91 1.75 5.00
63 INT64233 Regulation of Trp53 35 0.62 27.11 1.53 5.00
64 INT172953 Binding of Trp53 33 0.37 20.76 1.41 5.00
65 INT39877 Positive_regulation of EPX 13 0.69 6.01 1.21 5.00
66 INT169472 Gene_expression of PDIA2 15 0.58 7.88 0.96 5.00
67 INT101209 Gene_expression of Wt1 19 0.72 25.77 0.7 5.00
68 INT140037 Positive_regulation of Positive_regulation of Notch1 2 0.22 1.34 0.69 5.00
69 INT74016 Binding of VHL 20 0.48 15.49 0.54 5.00
70 INT242011 Localization of Cdkn2a 4 0.73 2.49 0.54 5.00
71 INT94165 Negative_regulation of RB1 30 0.52 27.29 0.51 5.00
72 INT242004 Binding of Tcf7 4 0.36 2.66 0.49 5.00
73 INT153861 Binding of EPX 9 0.46 0.49 0.41 5.00
74 INT283128 Positive_regulation of Positive_regulation of EPX 1 0.07 0.49 0.3 5.00
75 INT172957 Negative_regulation of Mdm2 4 0.14 4.28 0.3 5.00
76 INT213534 Positive_regulation of Ctnnd2 7 0.67 3.79 0.15 5.00
77 INT175453 Binding of Sftpd 2 0.23 2.04 0.15 5.00
78 INT283127 Regulation of Rtp 1 0.01 0.46 0.15 5.00
79 INT335179 Negative_regulation of Sftpd 1 0.21 2.61 0.06 5.00
80 INT183630 Regulation of Ctnnd2 3 0.26 1.11 0.05 5.00
81 INT225227 Gene_expression of NF2 4 0.65 4.49 0.03 5.00
82 INT242010 Positive_regulation of Wif1 1 0.03 0.52 0 5.00
83 INT217416 Positive_regulation of Positive_regulation of DLD 1 0.42 0.19 0 5.00
84 INT242002 Transcription of Tcf7 1 0.29 0.47 0 5.00
85 INT242003 Negative_regulation of Tgs1 1 0.01 1.09 0 5.00
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