D:Polycystic Ovary Syndrome

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Disease Term
Synonyms Anovulatory Hyperandrogenism, Cystic Ovaries, CYSTIC OVARY, LEVENTHAL DISEASE, Leventhal Syndrome, MICROPOLYCYSTIC OVARIES, Micropolycystic Ovary, MULTIPLE FOLLICLE CYST, Multiple Follicle Cysts, Ovarian Degeneration Sclerocystic, Ovaries Sclerocystic
Documents 371
Hot Single Events 200
Hot Interactions 40

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Polycystic Ovary Syndrome. They are ordered first by their relevance to Polycystic Ovary Syndrome and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT173704 Binding of PCOS1 and Edn1 1 0.01 0.99 0.37 100.00
2 INT295432 FSHR Positive_regulation of PCOS1 1 0.06 1.24 0 100.00
3 INT278250 Binding of PCOS1 and Ins1 1 0.00 1.23 0.04 100.00
4 INT278251 Binding of PCOS1 and Hypism 1 0.00 1.22 0.04 100.00
5 INT177425 Binding of Fig4 and Izumo1 1 0.12 0.59 0.23 99.92
6 INT177426 Izumo1 Positive_regulation of Positive_regulation of Fig4 1 0.16 0.59 0.34 99.76
7 INT328380 AR Negative_regulation of Gene_expression of Ghrl 1 0.01 0.55 0.07 99.74
8 INT334918 GNRH1 Positive_regulation of Gene_expression of FSHR 2 0.11 1.27 0.03 99.60
9 INT26468 Ghrh Positive_regulation of Localization of Gh 21 0.37 3.26 9.21 98.84
10 INT16221 Ghrh Positive_regulation of Gh 8 0.21 1.89 4.08 98.84
11 INT350114 Positive_regulation of GNRH1 Positive_regulation of FSHR 1 0.05 0.86 0.03 98.80
12 INT54584 GNRH1 Positive_regulation of FSHR 3 0.48 2.02 0.54 98.80
13 INT350119 Positive_regulation of GNRH1 Positive_regulation of PLOD1 1 0.04 0.86 0.03 98.48
14 INT45780 GNRH1 Positive_regulation of PLOD1 3 0.07 1.02 0.63 98.48
15 INT125748 Binding of LEP and Gh 1 0.00 0.52 0.24 98.20
16 INT350120 FSHR Regulation of CYP19A1 1 0.01 3.02 0 97.00
17 INT267154 ADIPOQ Regulation of Positive_regulation of SUGT1 1 0.03 1.18 0.08 96.96
18 INT65676 Binding of CGA and PLOD1 3 0.23 1.68 0.1 96.88
19 INT60536 Gnrh1 Positive_regulation of Localization of Prl 2 0.22 1.12 0.6 96.40
20 INT69566 Positive_regulation of Ghrh Regulation of Gh 1 0.04 1.66 0.55 96.16
21 INT10844 Ghrh Regulation of Gh 13 0.13 4.77 4.71 96.16
22 INT17623 Gnrh1 Positive_regulation of Localization of Lhb 4 0.72 1.46 0.71 94.84
23 INT213261 TNF Positive_regulation of CRP 1 0.24 1.59 0.06 94.00
24 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83 92.60
25 INT91391 Crh Regulation of Localization of Gnrh1 2 0.36 1.78 0.61 92.56
26 INT350117 GNRHR Negative_regulation of Localization of FSHR 1 0.01 1.06 0 92.48
27 INT350113 GNRHR Negative_regulation of Localization of PLOD1 1 0.01 1.06 0 92.48
28 INT350115 GNRH1 Negative_regulation of Localization of PLOD1 1 0.04 0.99 0 92.48
29 INT350122 GNRH1 Negative_regulation of Localization of FSHR 1 0.05 0.99 0 92.48
30 INT251469 INS Negative_regulation of Gene_expression of SHBG 2 0.11 4.11 0.08 92.36
31 INT59540 Crh Regulation of Gnrh1 2 0.36 2.61 0.58 91.92
32 INT350116 FSHR Positive_regulation of Gene_expression of CGA 1 0.01 1.28 0 90.64
33 INT319170 Casp3 Regulation of Hdac1 1 0.01 0.27 0 89.96
34 INT284891 FSHR Positive_regulation of Gene_expression of PLOD1 2 0.03 1.32 0.11 89.80
35 INT17622 Ass1 Positive_regulation of Lhb 1 0.02 1.22 0.49 88.84
36 INT222466 Gnrh1 Regulation of Prl 1 0.14 1.16 0.07 88.56
37 INT350121 INS Negative_regulation of Positive_regulation of SHBG 1 0.09 1.48 0.04 87.64
38 INT350118 INS Negative_regulation of SHBG 1 0.09 1.42 0.04 87.64
39 INT213264 INS Positive_regulation of Localization of IGF1 1 0.16 1.77 0 86.64
40 INT213262 IL6 Positive_regulation of CYP19A1 1 0.11 1.63 0.03 84.12
41 INT199973 ESR1 Negative_regulation of EEF1B2P2 1 0.01 0.46 0.08 78.32
42 INT192356 Binding of CP and CRP 1 0.16 4.35 0 76.88
43 INT267152 Binding of LEP and DDX12P 1 0.00 0.69 0.05 76.80
44 INT267153 Binding of LEP and SUGT1 1 0.02 0.69 0.05 76.80
45 INT213263 INS Positive_regulation of EDN1 1 0.12 0.54 0.04 76.44
46 INT199970 CYP19A1 Positive_regulation of Gene_expression of ESR1 1 0.06 0.72 0.25 74.88
47 INT1392 Trh Regulation of Prl 15 0.29 2.47 4.29 74.16
48 INT186540 Binding of Cort and Hpse 1 0.05 0.92 0.08 70.00
49 INT217661 LEP Positive_regulation of INS 2 0.25 1.85 0.19 69.36
50 INT217665 ADIPOQ Positive_regulation of INS 2 0.06 1.8 0.19 69.36
51 INT199971 IL6 Positive_regulation of ESR1 1 0.08 0.84 0.24 69.04
52 INT267157 LEP Positive_regulation of ADIPOQ 1 0.10 0.51 0.05 68.72
53 INT186539 Crh Regulation of Hpse 1 0.09 0.52 0.1 59.96
54 INT235596 HNF4A Regulation of Gene_expression of TPI1 1 0.00 0.25 0 59.44
55 INT290565 Binding of Rare1 and Rorb 1 0.00 0.32 0.12 56.72
56 INT222506 Gnrh1 Regulation of Localization of Prl 1 0.20 0.16 0.08 54.00
57 INT41006 GNRH1 Negative_regulation of Localization of CGA 1 0.03 0.87 0.3 53.44
58 INT290563 Binding of Rxrg and Rorb 1 0.00 0.2 0.12 51.68
59 INT7247 Binding of GNRH1 and Lhb 2 0.08 0 0.22 50.00
60 INT55914 GNRH1 Positive_regulation of Localization of Lhb 1 0.13 0 0 50.00
61 INT270746 INS Regulation of LEP 1 0.07 0.72 0.11 43.44
62 INT332907 Binding of LPL and SUGT1 1 0.00 1.3 0 40.16
63 INT314373 Binding of Cd34 and Eng 1 0.08 0.9 0 38.00
64 INT314371 Binding of Cd34 and Thy1 1 0.08 0.9 0 38.00
65 INT314374 Binding of Ptprc and Thy1 1 0.04 0.85 0 37.28
66 INT314372 Binding of Eng and Ptprc 1 0.04 0.84 0 37.28
67 INT295431 FSHR Positive_regulation of CGA 1 0.29 0.27 0 36.28
68 INT332943 Binding of SNRNP70 and Adipoq 1 0.00 1.35 0 32.40
69 INT332904 Binding of LEP and SNRNP70 1 0.00 1.34 0 31.36
70 INT235313 Cyp3a23/3a1 Positive_regulation of Ins1 1 0.14 0.82 0.05 31.04
71 INT332905 Binding of LPL and SNRNP70 1 0.01 1.34 0 30.72
72 INT199975 ESR1 Positive_regulation of PGR 1 0.05 0.11 0 27.84
73 INT285666 PPARA Positive_regulation of TGFB1I1 1 0.15 0.82 0 18.96
74 INT216711 P2RY1 Negative_regulation of P2RY12 1 0.28 0.09 0.16 18.32
75 INT211860 PLOD1 Regulation of AGRP 1 0.07 0.15 0.14 13.96
76 INT268652 Binding of CLDN4 and LIF 1 0.35 0.44 0.04 8.16
77 INT2161 Gnrh1 Positive_regulation of Localization of LH 33 0.73 0.87 14.34 5.00
78 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 0.64 2.12 14.2 5.00
79 INT2714 Pomc Positive_regulation of Localization of Prl 17 0.79 0.5 8.18 5.00
80 INT20133 Trh Positive_regulation of Localization of Prl 23 0.78 2.04 5.44 5.00
81 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 5.00
82 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79 5.00
83 INT9786 Gnrh1 Regulation of LH 7 0.40 0.58 1.82 5.00
84 INT279165 Calca Regulation of Gene_expression of Fdft1 1 0.02 0.41 1.37 5.00
85 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25 5.00
86 INT62368 Gal Positive_regulation of Localization of LH 3 0.36 0 1.2 5.00
87 INT222516 Binding of Calcrl and Ramp1 5 0.17 0.11 1.12 5.00
88 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
89 INT36186 Npy Positive_regulation of Localization of Gnrh1 4 0.75 0.09 0.96 5.00
90 INT206857 Binding of Calca and Calcrl 4 0.37 1.9 0.95 5.00
91 INT232426 HRH2 Regulation of Localization of PRL 1 0.15 0.38 0.94 5.00
92 INT279166 Binding of Cyp3a23/3a1 and Nr3c2 1 0.00 0.61 0.9 5.00
93 INT78062 Il1a Positive_regulation of Localization of Il6 3 0.24 0.48 0.9 5.00
94 INT132318 Ghrl Positive_regulation of Localization of GH1 5 0.32 4.49 0.84 5.00
95 INT222528 Abat Positive_regulation of Gene_expression of Gh1 1 0.01 0 0.75 5.00
96 INT123229 OXTR Regulation of Localization of PRL 2 0.30 0 0.73 5.00
97 INT222432 Binding of Tlr4 and Cd14 1 0.02 0.74 0.71 5.00
98 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71 5.00
99 INT32715 Prl Regulation of Localization of LH 2 0.34 0.09 0.68 5.00
100 INT60283 Positive_regulation of Gnrh1 Regulation of LH 2 0.31 0 0.68 5.00
101 INT222552 Abat Regulation of Gene_expression of Gh1 1 0.00 0 0.67 5.00
102 INT222492 Ngf Positive_regulation of Gene_expression of Prl 1 0.24 0 0.62 5.00
103 INT3617 Trh Regulation of Localization of Gh1 3 0.65 0.55 0.62 5.00
104 INT89902 SST Positive_regulation of Localization of PRL 2 0.40 0 0.61 5.00
105 INT27067 Crh Positive_regulation of Localization of Avp 3 0.18 0.46 0.61 5.00
106 INT32747 Avp Positive_regulation of Localization of Pomc 4 0.16 1.92 0.61 5.00
107 INT222521 Vip Positive_regulation of Localization of Ngf 1 0.14 0.08 0.6 5.00
108 INT222554 Il1a Positive_regulation of Localization of Ngf 1 0.02 0.07 0.6 5.00
109 INT199976 EGF Regulation of ITGB3BP 1 0.02 0.77 0.57 5.00
110 INT232424 VIP Positive_regulation of Localization of PRL 1 0.36 0 0.53 5.00
111 INT222524 Abat Negative_regulation of Localization of Trh 1 0.02 0.16 0.51 5.00
112 INT285688 Cpox Positive_regulation of PPARA 1 0.02 1 0.5 5.00
113 INT328385 Binding of GHS and Ghrl 1 0.15 1.89 0.45 5.00
114 INT232427 ABAT Regulation of PRL 1 0.08 0.26 0.45 5.00
115 INT328377 Binding of GAST and Ghrl 1 0.03 0.62 0.43 5.00
116 INT222490 Npy Positive_regulation of Localization of Gh1 1 0.02 0.06 0.41 5.00
117 INT222418 Tlr4 Positive_regulation of Gene_expression of Il1a 1 0.00 0.31 0.39 5.00
118 INT333969 Binding of TNF and Cd4 1 0.03 1.28 0.39 5.00
119 INT199974 ESR1 Negative_regulation of Gene_expression of ITGB3BP 1 0.05 0.47 0.38 5.00
120 INT232422 VIP Regulation of Gene_expression of PRL 1 0.40 0 0.37 5.00
121 INT232421 Binding of PRL and Positive_regulation of Regulation of ABAT 1 0.09 0 0.37 5.00
122 INT216709 Binding of SELP and PSMG1 3 0.08 1.48 0.37 5.00
123 INT3616 Trh Positive_regulation of Localization of Gh1 4 0.73 0.49 0.36 5.00
124 INT232419 ABAT Positive_regulation of Localization of PRL 1 0.09 0 0.33 5.00
125 INT232425 Binding of ABAT and Positive_regulation of PRL 1 0.09 0.15 0.33 5.00
126 INT232420 PRL Positive_regulation of Regulation of ABAT 1 0.09 0 0.33 5.00
127 INT222441 Tlr4 Positive_regulation of Gene_expression of Tac1 1 0.00 0.39 0.32 5.00
128 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31 5.00
129 INT187603 Binding of Ptgis and Ppara 1 0.00 0.26 0.31 5.00
130 INT328299 Binding of GHRH and GHS 1 0.07 2.21 0.31 5.00
131 INT222464 Col4a2 Regulation of Localization of Prl 1 0.03 0.32 0.3 5.00
132 INT222529 Binding of Trh and Vip 1 0.07 0.09 0.29 5.00
133 INT126696 Binding of Crhr1 and Crh 3 0.50 0.44 0.29 5.00
134 INT199978 ESR1 Regulation of ITGB3BP 1 0.03 0.39 0.28 5.00
135 INT222428 Negative_regulation of Tlr4 Positive_regulation of Il6 1 0.01 0.26 0.27 5.00
136 INT222412 Cd14 Negative_regulation of Binding of Tlr4 1 0.02 0.26 0.27 5.00
137 INT222440 Tlr4 Positive_regulation of Localization of Pomc 1 0.01 0.35 0.27 5.00
138 INT222427 Il6 Positive_regulation of Localization of Pomc 1 0.02 0.27 0.26 5.00
139 INT222422 Tlr4 Positive_regulation of Il6 1 0.01 0.25 0.26 5.00
140 INT222467 Gh1 Positive_regulation of Prl 1 0.04 0.52 0.26 5.00
141 INT222557 Gal Positive_regulation of Gene_expression of Vip 1 0.06 0.07 0.25 5.00
142 INT222421 Tlr4 Negative_regulation of Localization of Prl 1 0.02 0.45 0.25 5.00
143 INT328378 GH1 Regulation of Gene_expression of Ghrl 1 0.02 0.39 0.25 5.00
144 INT222563 Vip Positive_regulation of Gene_expression of Il6 1 0.05 0.38 0.25 5.00
145 INT222560 Calca Positive_regulation of Gene_expression of Il6 1 0.06 0.39 0.25 5.00
146 INT222540 Mzb1 Positive_regulation of Gene_expression of Il6 1 0.03 0.38 0.25 5.00
147 INT328382 Positive_regulation of Ghrl Positive_regulation of Localization of INS 1 0.03 1.08 0.23 5.00
148 INT222561 Gnrh1 Positive_regulation of Prl 1 0.15 0.38 0.22 5.00
149 INT207845 Binding of INS and Hypism 3 0.04 2.88 0.22 5.00
150 INT222527 Gal Regulation of Vip 1 0.03 0.05 0.22 5.00
151 INT295430 BRD2 Positive_regulation of PLOD1 1 0.02 0.33 0.22 5.00
152 INT222566 Agt Positive_regulation of Localization of Prl 1 0.08 0.23 0.21 5.00
153 INT295434 BRD2 Positive_regulation of Gene_expression of GNRH1 1 0.02 0.07 0.2 5.00
154 INT222482 Lep Positive_regulation of Localization of Gh1 1 0.02 1.02 0.2 5.00
155 INT216705 Binding of MARS and P2RY1 1 0.06 0 0.2 5.00
156 INT222568 Vip Negative_regulation of Transcription of Nos2 1 0.06 0.3 0.19 5.00
157 INT222543 Il1a Regulation of Chat 1 0.01 0.64 0.19 5.00
158 INT222525 Il1a Regulation of Localization of Gh1 1 0.00 0.64 0.19 5.00
159 INT222499 Il10 Regulation of Positive_regulation of Hpse 1 0.00 0.8 0.19 5.00
160 INT222473 Mzb1 Negative_regulation of Transcription of Nos2 1 0.04 0.29 0.19 5.00
161 INT222494 Negative_regulation of Il1a Negative_regulation of Positive_regulation of Il6 1 0.00 0.79 0.19 5.00
162 INT328310 DBT Positive_regulation of Localization of GH1 1 0.00 0 0.19 5.00
163 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19 5.00
164 INT287145 Binding of PNN and Shbg 1 0.07 0.14 0.18 5.00
165 INT222531 Il6 Positive_regulation of Hpse 1 0.00 0.61 0.18 5.00
166 INT222661 IFNA1 Positive_regulation of Gene_expression of Nos1 1 0.01 0.25 0.18 5.00
167 INT222414 Tlr4 Positive_regulation of Hpse 1 0.00 0.61 0.18 5.00
168 INT222470 Prl Regulation of Gnrh1 1 0.14 0.09 0.18 5.00
169 INT1394 Binding of Prl and LH 3 0.36 0 0.17 5.00
170 INT222443 INCENP Positive_regulation of Localization of Pomc 1 0.00 0.75 0.17 5.00
171 INT222426 Lif Positive_regulation of Localization of Pomc 1 0.02 0.75 0.17 5.00
172 INT222505 Gene_expression of Crh Negative_regulation of Gene_expression of Hpse 1 0.02 0.55 0.17 5.00
173 INT328386 GHS Positive_regulation of Localization of Ghrl 1 0.10 0.88 0.17 5.00
174 INT65677 Binding of CGA and FSHR 2 0.25 0.29 0.16 5.00
175 INT222509 Ghrh Positive_regulation of Localization of Prl 1 0.28 0.23 0.16 5.00
176 INT222430 Il11 Positive_regulation of Localization of Pomc 1 0.01 0.69 0.16 5.00
177 INT295433 Binding of PLOD1 and SCN5A 1 0.07 0.25 0.16 5.00
178 INT328379 Ghrl Positive_regulation of CRH 1 0.16 1.17 0.16 5.00
179 INT222548 Il11 Positive_regulation of Transcription of Pomc 1 0.03 0.7 0.16 5.00
180 INT222420 Tlr4 Positive_regulation of Positive_regulation of Hpse 1 0.00 0.67 0.15 5.00
181 INT39154 Crh Positive_regulation of Avp 2 0.11 0.15 0.14 5.00
182 INT222673 Gnrh1 Negative_regulation of Gnrh1 Positive_regulation of Prl 1 0.08 0.21 0.14 5.00
183 INT222551 Il6 Positive_regulation of Positive_regulation of Hpse 1 0.01 0.5 0.13 5.00
184 INT328374 GHRH Positive_regulation of Ghrl 1 0.13 0.26 0.13 5.00
185 INT258016 AGTR1 Positive_regulation of EGFR 1 0.15 1.24 0.13 5.00
186 INT197072 Binding of Slc3a1 and Atr 1 0.07 0.32 0.13 5.00
187 INT328384 Ghrl Positive_regulation of ALPL 1 0.01 0.93 0.13 5.00
188 INT222465 Binding of Calcrl and Rxfp2 1 0.02 0 0.12 5.00
189 INT328309 GHS Positive_regulation of Localization of GH1 1 0.04 0.99 0.12 5.00
190 INT222546 Mzb1 Positive_regulation of Localization of Prl 1 0.10 0.17 0.12 5.00
191 INT222549 Pomc Positive_regulation of Gnrh1 1 0.13 0 0.12 5.00
192 INT222507 Igf1 Positive_regulation of Localization of Edn3 1 0.05 0 0.11 5.00
193 INT269013 Binding of CSRP1 and COPD 1 0.08 1.3 0.11 5.00
194 INT328313 Binding of CD36 and LDLR 1 0.00 0.63 0.11 5.00
195 INT222472 Lep Positive_regulation of Localization of Cartpt 1 0.05 0 0.11 5.00
196 INT222503 Agt Positive_regulation of Localization of Gh1 1 0.02 0.23 0.11 5.00
197 INT328294 GHS Positive_regulation of Localization of GHRH 1 0.10 0.12 0.11 5.00
198 INT328370 Binding of CD36 and Fabp1 1 0.01 0.64 0.11 5.00
199 INT192358 CRP Regulation of Positive_regulation of HSPD1 1 0.15 2.46 0.1 5.00
200 INT192353 CRP Regulation of CP 1 0.20 2.46 0.1 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Polycystic Ovary Syndrome. They are ordered first by their pain relevance and then by number of times they were reported in Polycystic Ovary Syndrome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 100.00
2 INT270788 Regulation of AMH 4 0.54 7.54 0.2 100.00
3 INT114472 Regulation of Izumo1 13 0.48 7.95 3.2 100.00
4 INT37763 Negative_regulation of Izumo1 5 0.51 3.85 2.47 100.00
5 INT5128 Positive_regulation of Lhb 232 0.69 44.23 71.26 100.00
6 INT173703 Positive_regulation of PCOS1 3 0.01 3.76 1.05 100.00
7 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 100.00
8 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07 100.00
9 INT177423 Regulation of Regulation of Izumo1 1 0.21 0.95 0.42 100.00
10 INT3161 Regulation of Localization of Gh 163 0.61 35.43 59.45 100.00
11 INT177581 Regulation of Fig4 113 0.41 39.26 27.75 100.00
12 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 100.00
13 INT12316 Negative_regulation of Cort 10 0.38 5.89 6.08 100.00
14 INT177420 Positive_regulation of Regulation of Izumo1 1 0.36 0.58 0.34 100.00
15 INT187713 Gene_expression of PCOS1 1 0.04 2.09 0.19 100.00
16 INT14681 Negative_regulation of GCG 31 0.57 13.55 4.98 100.00
17 INT17094 Negative_regulation of SLC25A4 3 0.41 3.82 1.52 100.00
18 INT5126 Positive_regulation of Positive_regulation of Lhb 16 0.48 2.12 5.23 100.00
19 INT187728 Regulation of PCOS1 1 0.02 0.84 0.13 100.00
20 INT194343 Gene_expression of ABCC8 8 0.65 8.15 0.77 99.96
21 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 99.94
22 INT5130 Regulation of GNRH1 139 0.62 31.95 42.08 99.92
23 INT1200 Negative_regulation of Ins1 274 0.58 155.17 56.14 99.92
24 INT15576 Regulation of Regulation of GNRH1 4 0.34 0.27 1.97 99.92
25 INT847 Regulation of Lhb 131 0.61 22.08 46.54 99.88
26 INT17620 Positive_regulation of Gnrh1 23 0.70 9.77 3.79 99.88
27 INT35713 Gene_expression of Tmem131 9 0.50 6.13 0.96 99.86
28 INT1893 Localization of Gh 1041 0.79 340.23 256.58 99.84
29 INT111039 Gene_expression of Kras 20 0.60 15.42 2.39 99.84
30 INT5868 Positive_regulation of GNRH1 122 0.69 20.96 32.8 99.84
31 INT204058 Regulation of Gene_expression of Kras 4 0.24 7.54 1.01 99.84
32 INT4360 Gene_expression of Hypism 29 0.22 38.1 4.07 99.84
33 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 99.84
34 INT920 Localization of PLOD1 223 0.81 42.25 78.7 99.84
35 INT272438 Gene_expression of PROK1 32 0.63 15.06 1.01 99.84
36 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 99.84
37 INT199979 Gene_expression of ITGB3BP 1 0.11 2.83 1.08 99.84
38 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 99.84
39 INT1642 Negative_regulation of Localization of PLOD1 40 0.58 10.67 17.95 99.84
40 INT199983 Negative_regulation of Gene_expression of ITGB3BP 1 0.08 0.75 0.21 99.84
41 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 99.84
42 INT213278 Positive_regulation of Transcription of RETN 1 0.19 2 0.06 99.82
43 INT19078 Binding of Ngf 78 0.48 31.03 44.33 99.80
44 INT1114 Localization of Ins1 748 0.80 192.95 165.48 99.80
45 INT2275 Negative_regulation of Localization of Ins1 183 0.59 51.02 44.94 99.80
46 INT37764 Positive_regulation of Izumo1 21 0.61 8.75 5.79 99.78
47 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 99.76
48 INT166886 Negative_regulation of Gene_expression of Ghrl 3 0.41 4.11 0.66 99.74
49 INT3933 Positive_regulation of PLOD1 128 0.70 30.76 42.03 99.72
50 INT26538 Positive_regulation of FSHR 103 0.69 30.95 15.33 99.72
51 INT11636 Positive_regulation of SERPINE1 85 0.69 68.73 14.8 99.70
52 INT203491 Gene_expression of Msc 40 0.64 36.05 1.35 99.70
53 INT65907 Negative_regulation of Gene_expression of Ngf 36 0.59 19.5 20.03 99.68
54 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 99.68
55 INT140858 Negative_regulation of SUGT1 9 0.05 8.41 1.4 99.68
56 INT1335 Negative_regulation of Oprl1 123 0.59 18.02 77.13 99.68
57 INT6656 Gene_expression of YY1 135 0.75 24.73 72.16 99.68
58 INT7569 Positive_regulation of Transcription of Th 19 0.70 2.6 6.17 99.66
59 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 99.64
60 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 99.64
61 INT2123 Positive_regulation of Gnrh1 209 0.70 24.2 68.97 99.62
62 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56 99.60
63 INT4145 Gene_expression of FSHR 124 0.77 44.98 13.04 99.60
64 INT31981 Regulation of Regulation of Lhb 4 0.44 1.03 1.57 99.60
65 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18 99.58
66 INT3034 Localization of Ngf 126 0.81 50.81 72.84 99.56
67 INT266556 Positive_regulation of AMH 9 0.70 4.33 0.82 99.56
68 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.52
69 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 99.48
70 INT38631 Positive_regulation of Ret 8 0.39 3.23 2.52 99.48
71 INT111451 Regulation of ADIPOQ 24 0.56 18.81 2.47 99.48
72 INT61893 Gene_expression of Ghrl 125 0.75 71.49 15.14 99.44
73 INT162024 Gene_expression of Thl 4 0.63 3.24 0.55 99.44
74 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 99.42
75 INT4612 Positive_regulation of Localization of CGA 64 0.64 8.51 22.39 99.42
76 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73 99.42
77 INT1794 Regulation of Localization of CGA 136 0.57 13.39 59.07 99.42
78 INT7326 Transcription of Th 83 0.72 13.5 35.33 99.42
79 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 99.40
80 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 99.40
81 INT23491 Positive_regulation of FSHB 14 0.65 7.2 1.79 99.40
82 INT70622 Binding of Hypism 9 0.04 14.9 0.59 99.40
83 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 99.40
84 INT5345 Positive_regulation of BRD2 14 0.67 6.72 3.43 99.40
85 INT1793 Localization of CGA 379 0.81 67.38 114.69 99.36
86 INT4241 Regulation of CALCA 87 0.62 28.19 55.29 99.32
87 INT148756 Regulation of Adipoq 10 0.60 7.83 0.67 99.32
88 INT177422 Gene_expression of Izumo1 1 0.60 1.07 0.79 99.30
89 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04 99.28
90 INT9832 Gene_expression of Shbg 96 0.75 56.71 12.19 99.28
91 INT32688 Positive_regulation of Gene_expression of Shbg 14 0.45 7.01 1.6 99.28
92 INT913 Regulation of Localization of PLOD1 71 0.62 8.64 32.72 99.28
93 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 99.26
94 INT55908 Gene_expression of Ngfr 74 0.78 34.46 28.8 99.26
95 INT2005 Positive_regulation of Gene_expression of PRL 55 0.70 21.4 13.44 99.26
96 INT1638 Negative_regulation of PLOD1 92 0.59 21.69 26.61 99.24
97 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 99.22
98 INT2122 Negative_regulation of Localization of Gnrh1 226 0.59 26.92 92.04 99.20
99 INT2197 Gene_expression of Gnrh1 184 0.78 40.04 50.57 99.18
100 INT162 Regulation of Prl 794 0.62 165.01 322.24 99.16
101 INT213276 Transcription of RETN 1 0.28 1.98 0.06 99.14
102 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5 99.12
103 INT812 Localization of INS 1026 0.81 515.6 145.31 99.10
104 INT425 Localization of PRL 455 0.81 189.64 144.8 99.10
105 INT8089 Binding of Gnrh1 47 0.48 10.04 13.99 99.08
106 INT217 Negative_regulation of Th 134 0.59 26.83 62.63 99.08
107 INT67146 Positive_regulation of Gene_expression of Hypism 4 0.17 9.08 1.09 99.08
108 INT5127 Localization of Lhb 488 0.80 50.48 162.66 99.04
109 INT438 Gene_expression of Crh 376 0.78 159.11 169.17 99.04
110 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 99.04
111 INT125138 Positive_regulation of RETN 13 0.67 11.94 2.34 99.04
112 INT6299 Regulation of Localization of Lhb 104 0.61 8.98 48.79 99.04
113 INT213272 Negative_regulation of Phosphorylation of INS 7 0.40 9.13 0.44 99.00
114 INT107291 Positive_regulation of Ghrl 58 0.67 44.6 9.68 99.00
115 INT440 Regulation of Gene_expression of Crh 44 0.62 17.71 20.73 98.96
116 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24 98.96
117 INT147084 Binding of Slc30a8 4 0.37 1.95 0.2 98.96
118 INT2630 Positive_regulation of Shbg 134 0.70 65.26 15.19 98.92
119 INT8340 Negative_regulation of SHBG 49 0.57 35.96 4.73 98.92
120 INT109848 Gene_expression of P2RY1 26 0.62 6.71 4.98 98.92
121 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 98.90
122 INT439 Localization of Gnrh1 976 0.81 100.96 363.25 98.88
123 INT218 Positive_regulation of Th 245 0.70 40.5 120.1 98.88
124 INT14572 Binding of INS 205 0.48 175.43 13.38 98.88
125 INT14571 Regulation of Binding of INS 2 0.23 2.44 0.53 98.88
126 INT5806 Regulation of Edn1 63 0.62 23.46 13.88 98.88
127 INT4460 Regulation of Mpo 44 0.62 31.16 12.11 98.86
128 INT5781 Gene_expression of Edn1 190 0.78 99.1 46 98.84
129 INT114471 Negative_regulation of Positive_regulation of Izumo1 2 0.45 1.43 1.3 98.84
130 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 98.84
131 INT88935 Positive_regulation of SPP1 36 0.70 31.07 5.49 98.84
132 INT127273 Gene_expression of AMH 24 0.78 9.53 0.47 98.80
133 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19 98.80
134 INT199982 Positive_regulation of Gene_expression of SRA1 3 0.03 1.24 0.18 98.80
135 INT8027 Regulation of Gene_expression of Ngf 34 0.62 26.32 31.16 98.72
136 INT176594 Gene_expression of SRA1 20 0.35 9.65 1.15 98.70
137 INT1530 Regulation of Gh 382 0.61 115.96 112.47 98.68
138 INT45176 Negative_regulation of LPL 34 0.59 22.22 2.01 98.64
139 INT213274 Negative_regulation of Localization of LPL 1 0.15 1.89 0.09 98.64
140 INT3598 Regulation of Pla2g1b 12 0.44 3.45 3.9 98.62
141 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 98.56
142 INT10843 Regulation of Regulation of Gh 14 0.22 5.56 5.93 98.56
143 INT20179 Positive_regulation of Regulation of Gh 12 0.54 3.99 3.42 98.56
144 INT287142 Regulation of PNN 1 0.18 0.58 0 98.56
145 INT5048 Binding of Edn1 55 0.47 18.86 19.16 98.52
146 INT7975 Regulation of PLOD1 97 0.62 20.9 30.51 98.52
147 INT14097 Positive_regulation of Son 22 0.61 5.14 6.55 98.52
148 INT146295 Localization of GFER 1 0.68 1.46 0.38 98.52
149 INT8914 Regulation of Igfbp1 10 0.45 4.44 1.41 98.48
150 INT9334 Positive_regulation of Igfbp1 22 0.54 9.3 4.31 98.48
151 INT14562 Negative_regulation of Igfbp1 7 0.26 4.32 1.5 98.48
152 INT14561 Gene_expression of Igfbp1 12 0.35 6.27 2.46 98.48
153 INT213279 Positive_regulation of CYP17A1 1 0.40 1.53 0.06 98.44
154 INT7113 Negative_regulation of Localization of CGA 71 0.51 17.7 23.42 98.44
155 INT251 Regulation of INS 398 0.62 232.47 55.04 98.40
156 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 98.40
157 INT318008 Positive_regulation of Amh 1 0.25 1.47 0 98.40
158 INT127274 Positive_regulation of Gene_expression of AMH 5 0.61 1.4 0.29 98.38
159 INT213273 Phosphorylation of CYP17A1 1 0.74 1.56 0.07 98.36
160 INT1639 Negative_regulation of OPRM1 107 0.59 13.86 90.37 98.32
161 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88 98.32
162 INT4144 Gene_expression of SHBG 64 0.68 39.94 6.08 98.28
163 INT95272 Regulation of Gene_expression of Edn1 19 0.53 17.85 3.42 98.28
164 INT32795 Positive_regulation of Hypism 17 0.15 20.16 1.73 98.28
165 INT3602 Negative_regulation of Shbg 148 0.53 69.05 11.65 98.22
166 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 98.20
167 INT101959 Regulation of Rorb 10 0.14 5.18 3.17 98.20
168 INT1647 Negative_regulation of FSHR 54 0.45 13.44 8.87 98.16
169 INT49922 Positive_regulation of Positive_regulation of Ngf 21 0.67 14.46 17.68 98.16
170 INT14559 Gene_expression of Igf1 254 0.78 112 34.17 98.12
171 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79 98.12
172 INT8765 Positive_regulation of Cyp3a23/3a1 63 0.67 22.28 20.39 98.12
173 INT213281 Localization of LPL 3 0.21 3.48 0.28 98.12
174 INT32158 Positive_regulation of Positive_regulation of GNRH1 8 0.49 0.33 1.77 98.10
175 INT14560 Regulation of Igf1 41 0.59 19.59 6.3 98.08
176 INT89394 Phosphorylation of INS 37 0.82 35.84 3.9 98.08
177 INT3217 Regulation of Ins1 154 0.62 87.11 27.29 98.08
178 INT8741 Regulation of Positive_regulation of Ins1 5 0.41 1.36 1.67 98.08
179 INT13347 Regulation of Negative_regulation of OPRM1 5 0.45 0.64 3.38 98.04
180 INT61541 Positive_regulation of Gene_expression of Ngfr 7 0.53 2.87 2.75 98.00
181 INT8337 Negative_regulation of Gene_expression of Gnrh1 14 0.58 4.63 5.32 97.96
182 INT5503 Negative_regulation of Gene_expression of Crh 38 0.59 16.82 21.34 97.96
183 INT14368 Regulation of Gene_expression of Gnrhr 13 0.61 3.23 8.45 97.96
184 INT33071 Negative_regulation of Gene_expression of Gnrhr 13 0.53 5.99 4.41 97.96
185 INT5372 Localization of LHB 55 0.68 9.47 19 97.96
186 INT253 Regulation of PRL 184 0.62 47.27 65.79 97.92
187 INT7581 Binding of ADHD1 132 0.46 135.1 19.73 97.92
188 INT162023 Localization of THL 2 0.65 2.41 0.18 97.92
189 INT31778 Negative_regulation of Adrb2 2 0.07 1.34 0.72 97.86
190 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47 97.84
191 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 97.84
192 INT32623 Negative_regulation of Regulation of INS 16 0.43 10.96 2.9 97.74
193 INT7970 Gene_expression of PLOD1 120 0.71 44.42 15.54 97.72
194 INT177424 Positive_regulation of Gene_expression of Izumo1 1 0.39 0.1 0.16 97.68
195 INT75908 Regulation of LEP 77 0.60 60.16 15.19 97.56
196 INT1898 Regulation of Crh 220 0.62 61.33 102.64 97.40
197 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45 97.40
198 INT61116 Positive_regulation of Ppara 119 0.69 58.62 21.6 97.28
199 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 97.28
200 INT324622 Regulation of Gene_expression of AMH 1 0.39 0.51 0.04 97.26
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