D:Post-operative Nausea

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pChart

Disease Term
Synonyms Emeses Postoperative, Emesis Postoperative, NAUSEA POSTOPERATIVE, NAUSEA VOMITING POSTOPERATIVE, Ponv, Post Operative Nausea, Postoperative Emeses, Postoperative Emesis, Postoperative Nausea, POSTOPERATIVE NAUSEA VOMITING, POSTOPERATIVE VOMITING
Documents 1198
Hot Single Events 47
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Post-operative Nausea. They are ordered first by their relevance to Post-operative Nausea and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT232174 GAN Positive_regulation of ODT 1 0.01 0.98 0.14 87.80
2 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9 31.76
3 INT356199 GOPC Positive_regulation of Acot7 1 0.04 0.33 0.4 5.00
4 INT273561 Binding of CYP1A1 and CYP3A4 1 0.02 0.12 0.15 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Post-operative Nausea. They are ordered first by their pain relevance and then by number of times they were reported in Post-operative Nausea. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT61903 Negative_regulation of Slc43a1 3 0.34 2.18 0.3 100.00
2 INT232176 Regulation of Slc43a1 2 0.11 1.51 1.22 100.00
3 INT232180 Positive_regulation of Slc43a1 2 0.09 1.79 0.98 100.00
4 INT108911 Negative_regulation of Gene_expression of HTR3A 2 0.41 1.81 0.6 100.00
5 INT232179 Binding of Slc43a1 1 0.02 1.21 0.43 100.00
6 INT232177 Gene_expression of Slc43a1 2 0.04 1.06 0.4 100.00
7 INT232178 Localization of Slc43a1 1 0.04 0.81 0.71 100.00
8 INT29 Negative_regulation of Gast 74 0.59 24.85 24.96 99.80
9 INT312656 Negative_regulation of Protein_catabolism of Gast 1 0.02 2.12 1 99.80
10 INT84389 Transcription of HTR3A 2 0.69 0.3 0.94 99.80
11 INT1703 Regulation of PCa 52 0.52 23.65 20.6 99.64
12 INT232182 Regulation of ODT 1 0.07 1.07 0.46 99.40
13 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 99.40
14 INT65009 Gene_expression of HTR3A 29 0.75 8.51 10.59 99.28
15 INT325077 Positive_regulation of OR4G3P 1 0.29 0.96 0.27 99.18
16 INT145 Negative_regulation of H1 12 0.39 5.68 5.08 98.86
17 INT28981 Binding of Htr3b 4 0.28 1.67 1.27 98.80
18 INT162567 Gene_expression of Htr3b 1 0.52 0.47 0.32 98.80
19 INT29228 Negative_regulation of Binding of NCOR2 4 0.02 0.62 2.47 98.66
20 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 98.48
21 INT16268 Binding of HTR3A 15 0.47 7.38 7.18 98.40
22 INT312655 Protein_catabolism of Gast 1 0.05 1.05 0.49 98.40
23 INT6855 Binding of NCOR2 71 0.41 15.64 28.96 98.40
24 INT9230 Gene_expression of Htr3a 43 0.78 10.54 18.81 98.40
25 INT9231 Binding of Htr3a 27 0.47 7.29 13.04 98.40
26 INT139377 Gene_expression of HTR3B 3 0.75 0.79 0.45 98.12
27 INT232181 Positive_regulation of ODT 1 0.12 2.44 1.1 97.52
28 INT28 Regulation of Gast 106 0.62 26.37 29.85 96.84
29 INT164696 Localization of Depmq1 3 0.01 1.46 3.76 96.32
30 INT55874 Binding of GPM6A 20 0.34 4.2 13.63 95.88
31 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 94.04
32 INT23126 Regulation of HTR3A 10 0.60 5.42 4.81 93.44
33 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 93.24
34 INT1705 Gene_expression of pCA 126 0.65 88.65 34.81 93.12
35 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 92.32
36 INT16569 Negative_regulation of HTR3A 14 0.57 6.91 4.42 91.92
37 INT27590 Negative_regulation of Phex 5 0.36 2.38 2.26 91.08
38 INT310648 Negative_regulation of Negative_regulation of BCHE 2 0.27 1.79 0.59 88.96
39 INT25356 Positive_regulation of S100A12 18 0.69 17.62 3.38 88.68
40 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83 88.24
41 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4 88.08
42 INT60779 Negative_regulation of CYP3A 63 0.59 8.38 21.27 87.04
43 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27 87.00
44 INT3439 Localization of Abat 1017 0.78 112.39 727.06 84.72
45 INT68725 Regulation of Cyp11a1 6 0.19 2.62 0.44 84.56
46 INT95538 Localization of CYP2D6 21 0.81 5.69 4.73 81.28
47 INT130672 Binding of Ugt2b7 2 0.22 0.38 2.71 80.12
48 INT81761 Negative_regulation of Prep 12 0.55 8.48 4.73 78.72
49 INT27387 Binding of Aecp 4 0.34 5.09 1 75.00
50 INT1706 Negative_regulation of PCa 33 0.47 10.7 15.27 74.64
51 INT101898 Negative_regulation of Gan 1 0.43 0.71 1.14 73.36
52 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69 72.32
53 INT7715 Regulation of Drd2 35 0.62 10.79 22.3 71.92
54 INT187062 Regulation of Pip 3 0.17 1.71 0.37 71.56
55 INT3948 Regulation of Cck 291 0.62 58.07 255.88 70.88
56 INT46277 Positive_regulation of Regulation of Cck 5 0.70 1.35 4.31 70.88
57 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 69.32
58 INT17370 Negative_regulation of Negative_regulation of Ptgs1 16 0.22 6.5 6.12 69.32
59 INT1704 Positive_regulation of PCa 68 0.59 34.92 23.36 67.92
60 INT153098 Positive_regulation of Transcription of PCA 1 0.35 0.46 1.08 67.92
61 INT2909 Positive_regulation of Abat 334 0.70 62.1 256.43 67.60
62 INT16323 Gene_expression of pr 62 0.66 36.14 38.26 67.16
63 INT110944 Transcription of PCA 3 0.52 2.49 1.13 66.80
64 INT27933 Gene_expression of NCOR2 65 0.72 31.35 24.23 66.16
65 INT41791 Positive_regulation of NTS 12 0.49 5.69 4.15 66.16
66 INT16568 Positive_regulation of HTR3A 14 0.67 4.82 6.01 63.92
67 INT35716 Positive_regulation of NCOR2 45 0.60 18 23.54 61.32
68 INT30 Gene_expression of Gast 158 0.78 99 41.45 59.80
69 INT4829 Positive_regulation of Localization of Abat 199 0.55 20.91 150.48 59.44
70 INT15262 Negative_regulation of Positive_regulation of Avp 22 0.58 3.28 10.81 56.60
71 INT15913 Negative_regulation of CYP2D6 174 0.59 22.45 70.91 50.00
72 INT56870 Gene_expression of CYP2D6 87 0.78 8.83 37.53 50.00
73 INT11077 Positive_regulation of Htr3a 63 0.67 15.61 22.7 50.00
74 INT39914 Negative_regulation of Cyp1a2 44 0.58 10.04 22 50.00
75 INT10798 Positive_regulation of CYP2D6 24 0.56 5.82 11.31 50.00
76 INT17867 Positive_regulation of Cyp1a2 39 0.69 2.58 7.57 50.00
77 INT65514 Gene_expression of Cyp1a2 25 0.77 6.12 4.6 50.00
78 INT90960 Positive_regulation of Gene_expression of CYP2D6 9 0.50 2.06 2.76 50.00
79 INT126498 Positive_regulation of Negative_regulation of Cyp1a2 2 0.41 1.21 2.64 50.00
80 INT113081 Negative_regulation of Gene_expression of Cyp1a2 6 0.58 1.68 2.39 50.00
81 INT143686 Negative_regulation of Gene_expression of CYP2D6 4 0.58 0.83 2.16 50.00
82 INT144386 Positive_regulation of Negative_regulation of CYP2D6 3 0.49 1.01 0.4 50.00
83 INT273509 Positive_regulation of Gene_expression of Cyp1a2 2 0.14 1.2 0.33 50.00
84 INT216566 Binding of Abcb1b 2 0.06 0.22 0.25 50.00
85 INT162566 Positive_regulation of Htr3b 1 0.38 0 0 50.00
86 INT9199 Positive_regulation of CEBPZ 111 0.67 30.99 28.45 48.12
87 INT180338 Binding of Cyp2d4 12 0.47 6.87 4.09 43.80
88 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26 37.12
89 INT69561 Positive_regulation of GSTM1 23 0.50 5.69 6.36 34.76
90 INT230829 Localization of Cyp2d4 3 0.63 0.61 5.18 32.44
91 INT351284 Regulation of Localization of AP1M2 1 0.04 0.85 1.9 31.76
92 INT351285 Localization of AP1M2 1 0.07 0.79 1.89 31.76
93 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54 25.00
94 INT22715 Positive_regulation of Gene_expression of Pth 29 0.64 22.53 2.31 25.00
95 INT86092 Localization of HTR3A 4 0.78 0.52 1.64 25.00
96 INT315766 Positive_regulation of Vas1 1 0.10 0.46 1.11 21.52
97 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 5.00
98 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 5.00
99 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 5.00
100 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06 5.00
101 INT4822 Localization of Ca2 417 0.80 99.57 96.45 5.00
102 INT940 Negative_regulation of Ptgs1 219 0.59 104.34 95.97 5.00
103 INT3441 Regulation of Localization of Abat 117 0.38 8.67 87.59 5.00
104 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 5.00
105 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08 5.00
106 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
107 INT69876 Negative_regulation of Nfkb1 147 0.58 89.81 55.5 5.00
108 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47 5.00
109 INT52531 Gene_expression of Nfkb1 153 0.75 82.84 42.9 5.00
110 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 5.00
111 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
112 INT23330 Binding of Chrna7 79 0.48 10.06 35.5 5.00
113 INT47764 Binding of Jun 106 0.48 22.62 31.39 5.00
114 INT10797 Binding of CYP2D6 86 0.48 15.09 31.16 5.00
115 INT651 Positive_regulation of PTGS1 93 0.69 37.27 29.18 5.00
116 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
117 INT76095 Positive_regulation of ISYNA1 117 0.55 79.73 25.86 5.00
118 INT66758 Binding of Nfkb1 97 0.48 50.65 23.65 5.00
119 INT105021 Binding of GOPC 187 0.40 60.39 20.38 5.00
120 INT68347 Negative_regulation of Cyp2d4 34 0.58 7.62 18.35 5.00
121 INT50403 Negative_regulation of CYP2C19 55 0.59 8.97 17.79 5.00
122 INT50579 Binding of CYP3A4 84 0.48 17.52 17.45 5.00
123 INT50404 Negative_regulation of CYP1A2 49 0.59 8.61 17.35 5.00
124 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 5.00
125 INT59929 Negative_regulation of CYP2C9 60 0.59 16.33 15.39 5.00
126 INT32706 Gene_expression of Cyp3a23/3a1 51 0.65 19.48 15.06 5.00
127 INT52233 Transcription of Jun 37 0.66 6.39 11.15 5.00
128 INT93129 Negative_regulation of KCNH2 42 0.54 9.63 10.85 5.00
129 INT55418 Regulation of CYP2D6 29 0.61 1.83 10.21 5.00
130 INT61599 Positive_regulation of CYP2C9 43 0.69 11.1 8.33 5.00
131 INT49751 Negative_regulation of Positive_regulation of PTGS1 12 0.45 4.73 7.23 5.00
132 INT7743 Binding of Hrh2 19 0.47 7.75 7.11 5.00
133 INT20899 Negative_regulation of GNAI1 12 0.57 4.24 6.07 5.00
134 INT168446 Gene_expression of Prep 25 0.64 15.17 5.94 5.00
135 INT14388 Regulation of TACR1 12 0.45 3.1 5.58 5.00
136 INT133508 Positive_regulation of TKTL1 8 0.60 6.37 4.8 5.00
137 INT12194 Gene_expression of Trf 38 0.69 18.1 4.56 5.00
138 INT140199 Positive_regulation of Gene_expression of Cyp3a23/3a1 9 0.45 4.91 4.56 5.00
139 INT47044 Positive_regulation of ORM1 5 0.68 0.58 4.46 5.00
140 INT51445 Binding of B3GAT1 9 0.47 4.64 3.95 5.00
141 INT67474 Negative_regulation of B3GAT1 9 0.57 5.43 3.73 5.00
142 INT61341 Positive_regulation of Prep 12 0.63 6.08 3.37 5.00
143 INT31 Negative_regulation of Gene_expression of Gast 10 0.42 5.3 3.34 5.00
144 INT227524 Positive_regulation of Gene_expression of Prep 13 0.48 7.69 3.28 5.00
145 INT64806 Binding of asa 10 0.30 4.11 3.14 5.00
146 INT76092 Localization of ISYNA1 10 0.66 7.72 3.11 5.00
147 INT16729 Positive_regulation of LOC308670 10 0.65 1.63 3.11 5.00
148 INT24904 Negative_regulation of PAPPA 13 0.57 9.93 2.74 5.00
149 INT86602 Binding of KCNH2 14 0.36 4.65 2.58 5.00
150 INT101342 Negative_regulation of CYP2A6 11 0.53 3.68 2.39 5.00
151 INT180343 Negative_regulation of Negative_regulation of Cyp2d4 2 0.36 0.49 2.38 5.00
152 INT61340 Regulation of Prep 7 0.50 6.13 2.31 5.00
153 INT69314 Binding of CYP3A 16 0.48 1.78 2.19 5.00
154 INT59673 Negative_regulation of Chrna6 8 0.30 2.31 2.16 5.00
155 INT107448 Positive_regulation of Jak2 8 0.50 5.33 1.98 5.00
156 INT101410 Negative_regulation of Positive_regulation of CYP2C9 5 0.42 0.23 1.96 5.00
157 INT100940 Regulation of Negative_regulation of Nfkb1 5 0.35 3.59 1.91 5.00
158 INT57063 Negative_regulation of HTR7 6 0.57 1.21 1.76 5.00
159 INT94934 Negative_regulation of COX1 3 0.57 3.27 1.75 5.00
160 INT69471 Localization of CYP3A 6 0.73 0.07 1.69 5.00
161 INT156198 Negative_regulation of Vas1 3 0.30 0.97 1.65 5.00
162 INT303913 Regulation of Regulation of CYP2D6 2 0.37 1.09 1.48 5.00
163 INT140052 Binding of Cish 12 0.39 1.63 1.1 5.00
164 INT70201 Negative_regulation of ESCO2 4 0.37 1.46 1.01 5.00
165 INT207156 Binding of TKTL1 3 0.22 0.93 0.99 5.00
166 INT209108 Positive_regulation of Negative_regulation of GOPC 6 0.33 1.72 0.51 5.00
167 INT21841 Positive_regulation of PPPD1 4 0.38 3.46 0.16 5.00
168 INT274763 Negative_regulation of Gene_expression of Trf 2 0.03 1.34 0.04 5.00
169 INT309024 Gene_expression of STK10 1 0.24 0.11 0 5.00
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