D:Pregnancy-induced Hypertension

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Disease Term
Synonyms Gestational Hypertension, Hypertension Gestational, Hypertension Pregnancy Induced, Hypertension Pregnancy Transient, Pregnancy Induced Hypertension, Pregnancy Transient Hypertension, TRANSIENT HYPERTENSION PREGNANCY
Documents 68
Hot Single Events 5
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Pregnancy-induced Hypertension. They are ordered first by their relevance to Pregnancy-induced Hypertension and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT186240 Binding of AGRP and SCN5A 2 0.13 1.19 0.1 93.56
2 INT312803 F2 Positive_regulation of NPEPPS 1 0.01 1.32 0.32 5.00
3 INT312802 F2 Positive_regulation of Binding of NPEPPS 1 0.01 1.33 0.32 5.00
4 INT244338 Slc12a7 Positive_regulation of SERPINH1 1 0.00 0.26 0.13 5.00
5 INT175246 Binding of F13A1 and SH2B2 1 0.00 2.24 0 5.00
6 INT200488 Binding of ACE and SUGT1 1 0.01 0.28 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Pregnancy-induced Hypertension. They are ordered first by their pain relevance and then by number of times they were reported in Pregnancy-induced Hypertension. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 98.80
2 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 98.66
3 INT314 Positive_regulation of Ren 212 0.70 66.68 55.56 97.24
4 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51 88.56
5 INT84180 Binding of F5 22 0.48 18.6 0.49 82.60
6 INT23174 Gene_expression of NLRP3 51 0.72 35.49 6.47 79.36
7 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 78.96
8 INT130372 Transcription of PDE5A 7 0.72 1.93 0.4 77.84
9 INT92877 Gene_expression of PDE5A 35 0.76 17.1 2.7 50.32
10 INT162803 Regulation of F5 3 0.44 3.68 0.81 42.80
11 INT67822 Binding of SERPINH1 17 0.36 19.05 7.24 21.80
12 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 20.52
13 INT242945 Localization of PDE5A 9 0.75 4.57 1.28 15.76
14 INT201474 Regulation of Acta1 3 0.18 1.98 0 11.60
15 INT23598 Binding of SCN5A 32 0.40 16 5.35 10.80
16 INT4498 Gene_expression of F2 83 0.65 57.4 10.8 6.56
17 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
18 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
19 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
20 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 5.00
21 INT5454 Localization of CRH 124 0.79 79.18 41.53 5.00
22 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24 5.00
23 INT20462 Binding of ESR1 210 0.44 102.7 26.34 5.00
24 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 5.00
25 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73 5.00
26 INT1792 Positive_regulation of CGA 123 0.70 64.73 20.79 5.00
27 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 5.00
28 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 5.00
29 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88 5.00
30 INT32515 Negative_regulation of B4GALNT1 82 0.43 28.1 17.46 5.00
31 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92 5.00
32 INT75908 Regulation of LEP 77 0.60 60.16 15.19 5.00
33 INT3002 Binding of SUGT1 62 0.24 55.9 14.91 5.00
34 INT3962 Regulation of AGT 50 0.62 20.96 13.01 5.00
35 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63 5.00
36 INT76434 Negative_regulation of PRKG1 25 0.58 10.36 10.81 5.00
37 INT101481 Positive_regulation of Lep 81 0.69 62.59 9.95 5.00
38 INT11859 Positive_regulation of Tbxa2r 44 0.61 22.62 9.61 5.00
39 INT20664 Binding of ACE 60 0.48 35.27 9.16 5.00
40 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 5.00
41 INT20205 Binding of IgG 108 0.46 66.68 8.57 5.00
42 INT621 Positive_regulation of SERPINH1 19 0.57 21.52 8.44 5.00
43 INT13539 Gene_expression of LTA 39 0.62 22.55 8.07 5.00
44 INT6957 Positive_regulation of OXTR 38 0.70 6.55 7.81 5.00
45 INT20348 Negative_regulation of Tbxa2r 47 0.59 19.88 7.68 5.00
46 INT35584 Binding of ACLY 22 0.35 31.78 7.17 5.00
47 INT9695 Negative_regulation of Csf2 41 0.57 31.65 6.28 5.00
48 INT55733 Negative_regulation of VTN 47 0.58 47.22 5.68 5.00
49 INT81796 Binding of AGRP 62 0.36 37.19 5.3 5.00
50 INT37661 Negative_regulation of SERPINC1 48 0.59 38.6 4.77 5.00
51 INT9842 Binding of F2 36 0.47 22.79 4.42 5.00
52 INT46121 Negative_regulation of SERPINH1 14 0.38 10.84 4.41 5.00
53 INT102187 Gene_expression of SH2B2 23 0.59 26.54 4.39 5.00
54 INT141665 Gene_expression of AGRP 83 0.67 43.43 4.24 5.00
55 INT44323 Positive_regulation of F8 32 0.60 24.88 3.89 5.00
56 INT20455 Positive_regulation of Bche 15 0.59 7.22 3.7 5.00
57 INT175262 Binding of SH2B2 18 0.36 22.85 3.18 5.00
58 INT15837 Binding of CGA 31 0.41 12.06 3.17 5.00
59 INT61791 Positive_regulation of SH2B2 9 0.50 8.36 2.99 5.00
60 INT14447 Localization of F2 20 0.79 12.77 2.67 5.00
61 INT71933 Positive_regulation of Gene_expression of F2 19 0.56 14.24 2.53 5.00
62 INT188756 Positive_regulation of AGRP 43 0.60 23.67 2.51 5.00
63 INT17857 Negative_regulation of Gene_expression of AGT 25 0.46 21.16 2.45 5.00
64 INT11183 Negative_regulation of SH2B2 4 0.34 6.99 2.12 5.00
65 INT55810 Negative_regulation of Positive_regulation of Crp 10 0.41 4.95 2.02 5.00
66 INT64709 Gene_expression of VTN 11 0.67 11.01 1.97 5.00
67 INT18007 Positive_regulation of C6orf25 23 0.66 14.98 1.95 5.00
68 INT216932 Positive_regulation of Negative_regulation of Il6 3 0.38 4.88 1.55 5.00
69 INT103043 Binding of PDE5A 16 0.37 7.79 1.12 5.00
70 INT70027 Positive_regulation of Gene_expression of C6orf25 10 0.62 7.21 0.83 5.00
71 INT92348 Binding of NPEPPS 3 0.04 2.94 0.71 5.00
72 INT109964 Binding of AKR1B1 4 0.31 3.95 0.7 5.00
73 INT173092 Regulation of BAI1 3 0.24 3.16 0.44 5.00
74 INT258991 Gene_expression of Emb 2 0.43 2.55 0.23 5.00
75 INT258990 Localization of Emb 1 0.21 0.98 0.21 5.00
76 INT258989 Binding of Emb 1 0.10 0.98 0.21 5.00
77 INT175260 Negative_regulation of Gene_expression of SH2B2 2 0.25 4.41 0.21 5.00
78 INT200617 Positive_regulation of Negative_regulation of Tbxa2r 1 0.10 0.63 0.04 5.00
79 INT269282 Regulation of PEA15 1 0.05 0.65 0 5.00
80 INT354032 Gene_expression of LEPROT 1 0.02 1.9 0 5.00
81 INT175261 Positive_regulation of Negative_regulation of VTN 1 0.02 0.77 0 5.00
82 INT354031 Regulation of Gene_expression of ANKHD1 1 0.05 0.29 0 5.00
83 INT257384 Positive_regulation of Positive_regulation of C6orf25 2 0.14 2.17 0 5.00
84 INT198676 Positive_regulation of Yes1 1 0.28 0.2 0 5.00
85 INT269280 Regulation of Binding of PEA15 1 0.05 0.65 0 5.00
86 INT211184 Positive_regulation of Binding of SCN5A 1 0.22 0.48 0 5.00
87 INT198678 Localization of Yes1 1 0.42 0.07 0 5.00
88 INT198677 Binding of Yes1 1 0.21 0.15 0 5.00
89 INT269281 Negative_regulation of PEA15 1 0.05 0.61 0 5.00
90 INT354033 Gene_expression of ANKHD1 1 0.07 0.58 0 5.00
91 INT211183 Binding of PGD 2 0.31 0.71 0 5.00
92 INT269279 Binding of PEA15 2 0.04 1.29 0 5.00
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