D:Pregnancy Complications

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms COMPLICATION PREGNANCY, COMPLICATIONS PREGNANCY, Pregnancy Complication
Documents 126
Hot Single Events 27
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Pregnancy Complications. They are ordered first by their relevance to Pregnancy Complications and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT312803 F2 Positive_regulation of NPEPPS 1 0.01 1.32 0.32 88.88
2 INT312802 F2 Positive_regulation of Binding of NPEPPS 1 0.01 1.33 0.32 88.88
3 INT175246 Binding of F13A1 and SH2B2 1 0.00 2.24 0 78.88
4 INT266806 Hand2 Regulation of Gene_expression of IL10 1 0.00 1.23 0.32 69.32
5 INT266804 Hand2 Regulation of Gene_expression of IL13 1 0.00 1.23 0.32 69.32
6 INT266805 Hand2 Regulation of Gene_expression of IL4 1 0.00 1.23 0.32 69.32
7 INT266771 Binding of NGF and GOPC 1 0.05 3.23 1.43 50.48
8 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85 5.00
9 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 5.00
10 INT229394 TPSD1 Positive_regulation of F2RL1 2 0.00 3.11 2.14 5.00
11 INT266764 TPSD1 Positive_regulation of F2RL1 Positive_regulation of Localization of SFTPA1 1 0.00 1.55 1.76 5.00
12 INT266768 NGF Positive_regulation of Localization of SFTPA1 1 0.01 1.65 1.6 5.00
13 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59 5.00
14 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76 5.00
15 INT266769 IL2 Positive_regulation of Localization of IL4 1 0.00 1.03 0.72 5.00
16 INT266765 IL2 Positive_regulation of Localization of IL10 1 0.01 1.03 0.72 5.00
17 INT175323 Tlr4 Positive_regulation of Gene_expression of TLR2 1 0.02 0.31 0.56 5.00
18 INT175326 SERPINH1 Regulation of Pnlip 1 0.00 0.53 0.49 5.00
19 INT175319 Negative_regulation of Nos2 Negative_regulation of Positive_regulation of Pnlip 1 0.01 0.83 0.34 5.00
20 INT266800 Dlst Positive_regulation of Localization of VEGFA 1 0.02 0.88 0.29 5.00
21 INT266766 Binding of PGR and GOPC 1 0.00 1.08 0.29 5.00
22 INT266803 Dlst Positive_regulation of VEGFA 1 0.01 0.96 0.25 5.00
23 INT266802 Dlst Positive_regulation of CCL5 1 0.00 0.95 0.25 5.00
24 INT175321 IL6 Positive_regulation of Localization of Oxt 1 0.01 0.7 0.25 5.00
25 INT175322 Oxt Positive_regulation of Gene_expression of PTGER2 1 0.00 0.09 0.25 5.00
26 INT266801 Dlst Positive_regulation of IL8 1 0.00 0.95 0.25 5.00
27 INT175324 Hsp90b1 Positive_regulation of TLR2 1 0.00 0.65 0.23 5.00
28 INT175317 Hsp90b1 Positive_regulation of Tlr4 1 0.02 0.66 0.23 5.00
29 INT175320 Tlr4 Positive_regulation of Gene_expression of Mmp9 1 0.01 0.54 0.21 5.00
30 INT175325 Binding of TLR2 and Tlr6 1 0.00 0.39 0.09 5.00
31 INT175327 Binding of TLR2 and Tlr1 1 0.00 0.39 0.09 5.00
32 INT284501 Positive_regulation of Binding of ICAM1 and ITGAL 1 0.06 0.2 0.07 5.00
33 INT284503 Binding of ICAM1 and ITGAM 1 0.05 0.2 0.07 5.00
34 INT284504 ITGAL Positive_regulation of Gene_expression of ITGAM 1 0.03 0.2 0.06 5.00
35 INT329830 Tlr4 Positive_regulation of Unk 1 0.16 0.83 0 5.00
36 INT334279 NR2E3 Negative_regulation of Gene_expression of IGFBP1 1 0.04 0 0 5.00
37 INT334280 NR2E3 Negative_regulation of Gene_expression of TF 1 0.02 0 0 5.00
38 INT334281 NR2E3 Negative_regulation of Gene_expression of PRL 1 0.04 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Pregnancy Complications. They are ordered first by their pain relevance and then by number of times they were reported in Pregnancy Complications. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT6481 Binding of TNF 624 0.48 510.2 214.82 99.72
2 INT84180 Binding of F5 22 0.48 18.6 0.49 99.44
3 INT81965 Gene_expression of F5 16 0.65 13.29 0.48 98.12
4 INT129703 Negative_regulation of ptd 3 0.37 2.63 1.87 96.48
5 INT175296 Negative_regulation of Pnlip 1 0.08 2.89 0.33 96.16
6 INT187017 Positive_regulation of Bcar1 2 0.44 2.02 0.27 94.72
7 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 92.64
8 INT14447 Localization of F2 20 0.79 12.77 2.67 92.44
9 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63 92.20
10 INT73667 Positive_regulation of F5 6 0.60 3.38 0.39 91.84
11 INT263932 Positive_regulation of PROCR 6 0.67 2.43 0.46 91.36
12 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64 90.32
13 INT443 Localization of POMC 1020 0.81 284.52 443.17 89.80
14 INT5454 Localization of CRH 124 0.79 79.18 41.53 89.80
15 INT92348 Binding of NPEPPS 3 0.04 2.94 0.71 87.84
16 INT90371 Localization of Hrec 28 0.05 19.11 10.12 86.64
17 INT90792 Localization of Il10 144 0.80 87.88 30.03 86.64
18 INT183820 Regulation of BCAR1 4 0.39 3.27 1.06 83.08
19 INT425 Localization of PRL 455 0.81 189.64 144.8 82.04
20 INT46088 Localization of F3 15 0.37 13.7 2.23 82.04
21 INT67339 Localization of IGFBP1 10 0.70 1.73 0.86 82.04
22 INT19637 Localization of TF 14 0.73 5.74 0.86 82.04
23 INT28521 Gene_expression of HBG2 56 0.77 16.62 8.64 81.84
24 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 81.28
25 INT2005 Positive_regulation of Gene_expression of PRL 55 0.70 21.4 13.44 81.28
26 INT2021 Binding of HBG2 13 0.36 4.2 2.65 81.28
27 INT22431 Negative_regulation of HBG2 20 0.58 6.6 3.33 80.80
28 INT37661 Negative_regulation of SERPINC1 48 0.59 38.6 4.77 79.56
29 INT55733 Negative_regulation of VTN 47 0.58 47.22 5.68 79.56
30 INT175262 Binding of SH2B2 18 0.36 22.85 3.18 78.88
31 INT175260 Negative_regulation of Gene_expression of SH2B2 2 0.25 4.41 0.21 77.44
32 INT11183 Negative_regulation of SH2B2 4 0.34 6.99 2.12 77.44
33 INT141665 Gene_expression of AGRP 83 0.67 43.43 4.24 77.28
34 INT102187 Gene_expression of SH2B2 23 0.59 26.54 4.39 77.12
35 INT35584 Binding of ACLY 22 0.35 31.78 7.17 75.44
36 INT37863 Regulation of HBG2 11 0.61 3.95 4.34 74.16
37 INT209033 Positive_regulation of Localization of IFN1@ 27 0.67 12.55 2.84 73.16
38 INT91663 Positive_regulation of Localization of IL12A 9 0.27 5.91 1.95 73.16
39 INT170754 Localization of IFN1@ 121 0.78 66.78 15.6 72.72
40 INT91667 Localization of IL12A 39 0.74 25.51 7.36 72.72
41 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39 69.44
42 INT93886 Positive_regulation of Gene_expression of PGR 19 0.52 15.78 1.89 68.88
43 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 68.80
44 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 68.80
45 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26 68.80
46 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 67.92
47 INT172529 Negative_regulation of Gene_expression of PGR 24 0.48 16.69 1.04 67.92
48 INT37722 Gene_expression of NCAM1 103 0.75 81.57 14.18 65.52
49 INT15804 Gene_expression of ISG20 83 0.75 44.33 10.58 65.52
50 INT11048 Gene_expression of CD69 59 0.67 42.85 6.4 65.52
51 INT197364 Gene_expression of MCAT 18 0.16 24.11 4.27 65.52
52 INT119641 Gene_expression of EBAG9 25 0.76 33.2 3.96 65.52
53 INT14778 Gene_expression of FCGR3A 25 0.75 16.25 3.86 65.52
54 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 65.20
55 INT20922 Positive_regulation of Localization of CRH 18 0.67 11.12 6.79 64.88
56 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 62.28
57 INT188756 Positive_regulation of AGRP 43 0.60 23.67 2.51 62.00
58 INT187016 Binding of Bcar1 1 0.31 1.36 0 60.52
59 INT173505 Localization of Hand2 63 0.57 45.32 13.66 59.24
60 INT63043 Positive_regulation of Gene_expression of HBG2 6 0.48 1.75 0.26 57.20
61 INT87340 Negative_regulation of BCAR1 8 0.38 6.96 2.63 56.88
62 INT183819 Negative_regulation of Positive_regulation of BCAR1 1 0.38 2.04 0.05 56.88
63 INT4046 Positive_regulation of HBG2 42 0.69 13.66 8.51 56.64
64 INT3403 Positive_regulation of BCAR1 18 0.63 18.95 3.23 56.48
65 INT6852 Localization of TNF 883 0.81 705.95 270.84 54.48
66 INT92248 Negative_regulation of F5 7 0.43 3.28 0.4 50.00
67 INT9842 Binding of F2 36 0.47 22.79 4.42 46.52
68 INT308082 Gene_expression of Drm 1 0.59 0.3 0.12 44.32
69 INT71150 Binding of NGF 22 0.46 13.67 14.81 44.16
70 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 39.80
71 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 37.68
72 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 37.68
73 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 37.68
74 INT7082 Gene_expression of CRH 180 0.78 64.66 31.74 35.40
75 INT3404 Binding of BCAR1 10 0.33 7.97 1.33 32.48
76 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 32.04
77 INT11288 Negative_regulation of CRH 44 0.00 16.69 12.37 29.20
78 INT9660 Regulation of TNF 363 0.62 312.94 139.99 28.28
79 INT6957 Positive_regulation of OXTR 38 0.70 6.55 7.81 27.04
80 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 14.80
81 INT15837 Binding of CGA 31 0.41 12.06 3.17 13.84
82 INT139678 Positive_regulation of Hspb8 23 0.68 23.94 1.85 11.76
83 INT81795 Negative_regulation of AGRP 23 0.41 10.93 0.87 5.44
84 INT188754 Localization of AGRP 15 0.74 8.88 0.6 5.44
85 INT197767 Positive_regulation of Negative_regulation of AGRP 1 0.45 1.26 0.04 5.44
86 INT197768 Positive_regulation of Localization of AGRP 2 0.48 1.75 0.04 5.44
87 INT44323 Positive_regulation of F8 32 0.60 24.88 3.89 5.08
88 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
89 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 5.00
90 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
91 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
92 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
93 INT626 Localization of CALCA 289 0.81 125.39 221.15 5.00
94 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
95 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 5.00
96 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
97 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 5.00
98 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 5.00
99 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
100 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 5.00
101 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 5.00
102 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 5.00
103 INT12339 Localization of IL8 437 0.81 251.87 117.39 5.00
104 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
105 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
106 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 5.00
107 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
108 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
109 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 5.00
110 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 5.00
111 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61 5.00
112 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 5.00
113 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 5.00
114 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 5.00
115 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 5.00
116 INT2893 Localization of Oxt 219 0.80 28.96 79.43 5.00
117 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45 5.00
118 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 5.00
119 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35 5.00
120 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 5.00
121 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 5.00
122 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 5.00
123 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 5.00
124 INT6849 Localization of IL1B 229 0.81 112.56 69.63 5.00
125 INT7344 Gene_expression of TAC1 132 0.75 35.48 68.26 5.00
126 INT9489 Gene_expression of SFTPA1 112 0.66 55.38 66.45 5.00
127 INT253 Regulation of PRL 184 0.62 47.27 65.79 5.00
128 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 5.00
129 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 5.00
130 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 5.00
131 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
132 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 5.00
133 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 5.00
134 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72 5.00
135 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
136 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01 5.00
137 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09 5.00
138 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 5.00
139 INT72182 Gene_expression of Mcpt1 167 0.75 123.7 52.15 5.00
140 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 5.00
141 INT937 Positive_regulation of Oxt 195 0.70 37.82 49.3 5.00
142 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9 5.00
143 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22 5.00
144 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
145 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 5.00
146 INT115384 Positive_regulation of Mmp9 121 0.68 94.74 43.02 5.00
147 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
148 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65 5.00
149 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82 5.00
150 INT29496 Gene_expression of MMP3 136 0.75 49.49 41.78 5.00
151 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
152 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94 5.00
153 INT8835 Localization of SFTPA1 65 0.68 32.81 38.65 5.00
154 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28 5.00
155 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17 5.00
156 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
157 INT927 Gene_expression of Oxt 184 0.78 44.71 35.79 5.00
158 INT100733 Positive_regulation of F2RL1 62 0.70 59.14 35.22 5.00
159 INT104392 Gene_expression of Cxcl10 113 0.75 106.86 34.12 5.00
160 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89 5.00
161 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72 5.00
162 INT10763 Localization of IL2 157 0.80 81.11 33.21 5.00
163 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68 5.00
164 INT56809 Binding of Tlr4 184 0.48 106.02 31.18 5.00
165 INT23435 Positive_regulation of NGF 54 0.70 32.41 30.11 5.00
166 INT10915 Gene_expression of ITGAM 164 0.78 92.42 29.78 5.00
167 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52 5.00
168 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
169 INT7035 Regulation of CGA 87 0.45 29.04 28.45 5.00
170 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71 5.00
171 INT21900 Gene_expression of Mthfd1 150 0.75 69.47 27.03 5.00
172 INT1765 Positive_regulation of Gene_expression of PTGER2 140 0.51 68.68 27 5.00
173 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 5.00
174 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 5.00
175 INT1761 Positive_regulation of PTGER2 135 0.49 90.17 26.26 5.00
176 INT47075 Positive_regulation of Ptger2 142 0.70 78.55 25.47 5.00
177 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12 5.00
178 INT10836 Negative_regulation of IL8 95 0.59 52.59 24.71 5.00
179 INT6441 Positive_regulation of CRH 98 0.69 57.22 24.12 5.00
180 INT8836 Positive_regulation of SFTPA1 36 0.47 28.37 23.59 5.00
181 INT956 Negative_regulation of PRL 94 0.59 42.72 23.01 5.00
182 INT74423 Localization of IL10 91 0.80 61.6 22.95 5.00
183 INT48081 Localization of Il1b 46 0.80 21.59 22.4 5.00
184 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26 5.00
185 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21 5.00
186 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22 5.00
187 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73 5.00
188 INT34488 Negative_regulation of MMP2 85 0.59 41.98 21.72 5.00
189 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37 5.00
190 INT1792 Positive_regulation of CGA 123 0.70 64.73 20.79 5.00
191 INT63340 Positive_regulation of Gene_expression of ICAM1 109 0.70 90.82 20.61 5.00
192 INT78901 Localization of CCL5 67 0.78 40.79 20.59 5.00
193 INT192409 Positive_regulation of Gene_expression of IFN1@ 102 0.67 64.66 18.8 5.00
194 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65 5.00
195 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 5.00
196 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88 5.00
197 INT2216 Gene_expression of SELL 92 0.77 59.29 17.71 5.00
198 INT168263 Gene_expression of IL23A 57 0.58 47.1 17.67 5.00
199 INT84464 Gene_expression of DPP4 101 0.78 56.15 17.53 5.00
200 INT1578 Negative_regulation of Localization of PRL 52 0.59 20.62 17.18 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox