D:Prehypertension

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pChart

Disease Term
Synonyms Pre Hypertension, Pre Hypertensions, Prehypertensions
Documents 19
Hot Single Events 20
Hot Interactions 3

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Prehypertension. They are ordered first by their relevance to Prehypertension and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT344965 Phc1 Regulation of HP 1 0.02 0.95 0.09 99.54
2 INT344964 Phc1 Positive_regulation of HP 1 0.04 1.36 0 94.64
3 INT155839 Binding of GGT1 and Shbg 1 0.07 1.21 0.12 93.28
4 INT344945 Negative_regulation of ACE Positive_regulation of REN 1 0.23 0.64 0.09 68.20
5 INT344963 Phc1 Regulation of REN 1 0.15 0.66 0.06 61.48
6 INT344946 AGT Regulation of Negative_regulation of ACE 1 0.21 0.61 0.14 51.56
7 INT344947 IPP Regulation of HP 1 0.03 0.81 0.12 39.44
8 INT260397 Positive_regulation of Hmox1 Positive_regulation of Gene_expression of Adipoq 1 0.37 0.78 0.22 5.00
9 INT260394 Positive_regulation of Hmox1 Positive_regulation of Adipoq 1 0.37 0.78 0.19 5.00
10 INT308551 Binding of HP and VPS45 1 0.04 0.44 0.15 5.00
11 INT260392 Hmox1 Positive_regulation of Adipoq 1 0.32 0.65 0.07 5.00
12 INT260395 Positive_regulation of Adipoq Negative_regulation of Gene_expression of Hmox1 1 0.34 1.4 0 5.00
13 INT260398 Dclk2 Regulation of Gene_expression of Hmox1 1 0.01 1.02 0 5.00
14 INT260393 Hmox1 Regulation of Positive_regulation of Bcl2 1 0.22 0.86 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Prehypertension. They are ordered first by their pain relevance and then by number of times they were reported in Prehypertension. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT14043 Binding of HP 52 0.30 26.56 7.76 100.00
2 INT165811 Binding of Phc1 13 0.15 5.99 3.09 99.84
3 INT344949 Regulation of Binding of Phc1 1 0.19 0.95 0.09 99.84
4 INT155838 Binding of GGT1 7 0.47 13.27 1.11 99.76
5 INT18011 Positive_regulation of HP 60 0.50 31.88 4.75 99.26
6 INT63177 Regulation of HP 71 0.44 39.48 5.86 99.10
7 INT1721 Negative_regulation of HP 148 0.42 86.82 16.89 97.60
8 INT344957 Regulation of Negative_regulation of HP 1 0.07 2.9 0.08 97.60
9 INT308562 Regulation of Localization of HP 2 0.07 2.11 0.03 97.60
10 INT33243 Localization of HP 17 0.12 9.7 2.2 97.60
11 INT344959 Positive_regulation of ATP6V0A4 1 0.03 0.95 0.08 95.56
12 INT344956 Regulation of ATP6V0A4 1 0.03 0.95 0.08 95.56
13 INT344955 Regulation of IPP 1 0.30 0.95 0.08 95.24
14 INT344958 Positive_regulation of IPP 1 0.31 0.95 0.08 95.24
15 INT163969 Positive_regulation of Hypt 6 0.41 6.24 0.49 94.76
16 INT9854 Localization of GGT1 11 0.78 6.09 3.57 93.44
17 INT183076 Regulation of Hypt 2 0.16 1.46 0 92.72
18 INT2630 Positive_regulation of Shbg 134 0.70 65.26 15.19 91.04
19 INT344960 Negative_regulation of LPP 1 0.23 0.83 0.1 82.88
20 INT8548 Gene_expression of HP 86 0.77 47.62 11.94 82.12
21 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92 79.32
22 INT660 Negative_regulation of REN 194 0.59 82.06 29.46 79.32
23 INT38992 Negative_regulation of Pnlip 6 0.48 3.91 1.14 75.80
24 INT86780 Positive_regulation of Hmox1 145 0.70 117.09 31.18 73.04
25 INT183075 Binding of Hypt 7 0.22 7.47 0.38 68.32
26 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 68.20
27 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 67.00
28 INT97096 Regulation of Hmox1 18 0.61 6.42 3.9 66.40
29 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 63.76
30 INT188973 Binding of Pm20d1 1 0.15 1.04 0 57.32
31 INT183080 Gene_expression of Hypt 5 0.14 7.53 0.85 54.72
32 INT183079 Negative_regulation of Gene_expression of Hypt 1 0.04 1.09 0 54.72
33 INT398 Localization of AGT 45 0.78 16.97 11.54 54.64
34 INT10104 Negative_regulation of Edn1 43 0.59 15.63 7.2 48.88
35 INT99287 Binding of GOLPH3 6 0.35 2.87 0.85 47.68
36 INT183081 Phosphorylation of Hypt 1 0.06 0.71 0 43.52
37 INT82450 Negative_regulation of Hmox1 33 0.55 19.07 8.12 39.72
38 INT183077 Negative_regulation of Hypt 1 0.04 1.69 0 39.00
39 INT308555 Negative_regulation of VPS45 1 0.57 6.37 0.25 37.92
40 INT183078 Protein_catabolism of Hypt 1 0.09 0.75 0 34.88
41 INT61591 Negative_regulation of Localization of EDN1 11 0.59 2.09 0.85 30.00
42 INT9191 Localization of EDN1 94 0.81 57.01 14.78 29.28
43 INT101414 Gene_expression of Phc1 27 0.60 9.55 7.58 24.28
44 INT81293 Positive_regulation of Gene_expression of Hmox1 53 0.70 41.54 7.25 19.24
45 INT117501 Positive_regulation of Gene_expression of Adipoq 24 0.63 12.99 3.1 19.24
46 INT76406 Gene_expression of Hmox1 140 0.78 85.86 17.15 17.84
47 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58 17.12
48 INT41985 Regulation of Regulation of HSD11B1 2 0.44 1.6 0.17 13.28
49 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 12.68
50 INT17913 Regulation of HSD11B1 87 0.60 93.23 6.04 11.92
51 INT34585 Negative_regulation of Positive_regulation of HSD11B1 31 0.57 43.54 2.47 5.36
52 INT10056 Positive_regulation of Fabp6 77 0.59 36.99 16.8 5.08
53 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
54 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 5.00
55 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 5.00
56 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
57 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39 5.00
58 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 5.00
59 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46 5.00
60 INT2660 Negative_regulation of Fabp6 58 0.49 33.74 18.27 5.00
61 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37 5.00
62 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 5.00
63 INT117502 Positive_regulation of Adipoq 70 0.63 40.43 12.03 5.00
64 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 5.00
65 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 5.00
66 INT3954 Regulation of Fabp6 33 0.52 15.64 9.27 5.00
67 INT83006 Gene_expression of AGTR1 59 0.75 54.46 7.27 5.00
68 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67 5.00
69 INT117721 Positive_regulation of Gene_expression of Akt1 22 0.69 6.26 6.08 5.00
70 INT91159 Negative_regulation of Ros1 35 0.44 26.12 5.97 5.00
71 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7 5.00
72 INT117499 Negative_regulation of Adipoq 28 0.56 24.15 5.07 5.00
73 INT9098 Positive_regulation of DBP 30 0.69 15.77 4.26 5.00
74 INT81291 Regulation of Gene_expression of Hmox1 11 0.60 8.78 2.46 5.00
75 INT130392 Positive_regulation of Gene_expression of HP 7 0.69 7.34 1.9 5.00
76 INT99742 Negative_regulation of Gene_expression of Hmox1 12 0.58 9.94 1.77 5.00
77 INT86247 Gene_expression of Bcl2l10 14 0.34 12.21 1.61 5.00
78 INT91232 Regulation of Positive_regulation of Hmox1 5 0.45 2.43 1.55 5.00
79 INT103305 Positive_regulation of Positive_regulation of Hmox1 8 0.49 4.81 1.49 5.00
80 INT173100 Binding of KDR 39 0.39 22.48 0.81 5.00
81 INT124844 Regulation of Positive_regulation of Bcl2 3 0.43 2.55 0.75 5.00
82 INT157378 Gene_expression of PDR 14 0.53 11.46 0.64 5.00
83 INT308553 Positive_regulation of VPS45 1 0.45 1.22 0.43 5.00
84 INT308557 Gene_expression of VPS45 1 0.66 1.12 0.4 5.00
85 INT206454 Positive_regulation of Localization of HP 2 0.05 0.82 0.39 5.00
86 INT308559 Regulation of VPS45 1 0.44 1.72 0.37 5.00
87 INT46932 Positive_regulation of Binding of HP 1 0.36 1.67 0.28 5.00
88 INT19240 Positive_regulation of Dclk2 3 0.28 1.36 0.28 5.00
89 INT260399 Positive_regulation of Sod3 1 0.19 1.4 0.24 5.00
90 INT213242 Negative_regulation of Gene_expression of HP 3 0.04 0.88 0.17 5.00
91 INT308566 Positive_regulation of Positive_regulation of VPS45 1 0.45 0.36 0.17 5.00
92 INT308560 Negative_regulation of Positive_regulation of VPS45 1 0.42 0.36 0.17 5.00
93 INT213241 Regulation of Regulation of HP 2 0.03 1.26 0.12 5.00
94 INT308567 Binding of VPS45 1 0.32 2.48 0.08 5.00
95 INT260401 Negative_regulation of Positive_regulation of Sod3 1 0.11 0.82 0.05 5.00
96 INT308561 Regulation of Binding of VPS45 1 0.38 0.79 0.03 5.00
97 INT183082 Transcription of Hypt 1 0.07 1.02 0.03 5.00
98 INT308558 Positive_regulation of Binding of VPS45 1 0.43 0.66 0 5.00
99 INT308556 Regulation of Negative_regulation of VPS45 1 0.44 0.45 0 5.00
100 INT206452 Negative_regulation of Binding of HP 2 0.04 0.84 0 5.00
101 INT308564 Positive_regulation of Negative_regulation of VPS45 1 0.43 0.71 0 5.00
102 INT157703 Positive_regulation of Positive_regulation of HP 2 0.42 0.76 0 5.00
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