D:Premature Menopause

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pChart

Disease Term
Synonyms None
Documents 27
Hot Single Events 10
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Premature Menopause. They are ordered first by their relevance to Premature Menopause and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT222299 Binding of CYP19A1 and AIS 2 0.25 1.65 0.31 5.00
2 INT284891 FSHR Positive_regulation of Gene_expression of PLOD1 2 0.03 1.32 0.11 5.00
3 INT284892 AMH Regulation of Localization of FSHR 1 0.01 0.18 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Premature Menopause. They are ordered first by their pain relevance and then by number of times they were reported in Premature Menopause. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT34058 Gene_expression of FMR1 5 0.75 5.11 0.26 98.20
2 INT170886 Gene_expression of AIRE 2 0.49 4.63 0.19 98.20
3 INT180359 Localization of AIRE 3 0.54 3.94 0.03 95.76
4 INT72878 Positive_regulation of crf 5 0.26 6.47 0.63 95.56
5 INT79270 Gene_expression of MKI67 113 0.77 63.52 3.38 90.32
6 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 87.84
7 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 87.44
8 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 87.44
9 INT237093 Binding of crf 5 0.38 16.18 0.38 81.12
10 INT180588 Gene_expression of HEYL 13 0.52 8.37 1.19 80.56
11 INT180580 Binding of HEYL 7 0.17 4.49 1.15 71.52
12 INT2261 Gene_expression of Lhb 121 0.77 42.78 26.04 62.16
13 INT199004 Gene_expression of ARMC9 43 0.58 17.72 1.32 51.32
14 INT6441 Positive_regulation of CRH 98 0.69 57.22 24.12 46.80
15 INT28088 Binding of Alb 34 0.47 11.06 5.48 44.20
16 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 41.60
17 INT7397 Negative_regulation of Localization of GNRH1 86 0.59 15.45 29.78 41.60
18 INT5455 Negative_regulation of Localization of CRH 16 0.49 7.31 6.41 40.56
19 INT5864 Localization of IL36RN 19 0.44 14.5 6.87 39.76
20 INT5454 Localization of CRH 124 0.79 79.18 41.53 36.56
21 INT7970 Gene_expression of PLOD1 120 0.71 44.42 15.54 22.88
22 INT4145 Gene_expression of FSHR 124 0.77 44.98 13.04 22.88
23 INT147583 Gene_expression of AIS 82 0.58 48.7 7.11 18.00
24 INT26538 Positive_regulation of FSHR 103 0.69 30.95 15.33 15.92
25 INT151342 Positive_regulation of Positive_regulation of FSHR 5 0.20 1.79 0.11 15.92
26 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 5.00
27 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 5.00
28 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
29 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 5.00
30 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
31 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 5.00
32 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 5.00
33 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71 5.00
34 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65 5.00
35 INT5130 Regulation of GNRH1 139 0.62 31.95 42.08 5.00
36 INT3933 Positive_regulation of PLOD1 128 0.70 30.76 42.03 5.00
37 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19 5.00
38 INT7975 Regulation of PLOD1 97 0.62 20.9 30.51 5.00
39 INT10506 Gene_expression of PTAFR 86 0.76 37.57 28.58 5.00
40 INT1638 Negative_regulation of PLOD1 92 0.59 21.69 26.61 5.00
41 INT48766 Regulation of NOS1 73 0.61 37.01 24.59 5.00
42 INT89854 Regulation of Nos2 49 0.61 42.58 24.1 5.00
43 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 5.00
44 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 5.00
45 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21 5.00
46 INT1644 Regulation of FSHR 77 0.55 15.62 21.49 5.00
47 INT66281 Transcription of Nos2 81 0.71 39.49 20.37 5.00
48 INT89484 Gene_expression of TNFRSF11B 119 0.76 53.57 19.67 5.00
49 INT5160 Localization of PTAFR 61 0.80 42.6 19.16 5.00
50 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 5.00
51 INT27670 Negative_regulation of Ace 122 0.57 79.21 18.08 5.00
52 INT77433 Regulation of Gene_expression of Nos2 49 0.62 35.07 16.33 5.00
53 INT912 Localization of FSHR 91 0.79 23.61 15.58 5.00
54 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 5.00
55 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36 5.00
56 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 5.00
57 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 5.00
58 INT130867 Gene_expression of TNFSF11 106 0.77 45.15 10.34 5.00
59 INT11859 Positive_regulation of Tbxa2r 44 0.61 22.62 9.61 5.00
60 INT38564 Binding of AIS 36 0.38 27.77 9.31 5.00
61 INT119904 Regulation of CYP19A1 25 0.62 9.36 8.34 5.00
62 INT173808 Positive_regulation of CYP27A1 35 0.68 23.7 7.87 5.00
63 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53 5.00
64 INT30443 Positive_regulation of AIS 30 0.54 22.59 7.2 5.00
65 INT9683 Binding of GH1 57 0.47 21.14 5.99 5.00
66 INT13396 Gene_expression of DMD 125 0.75 57.81 5.45 5.00
67 INT924 Regulation of Localization of FSHR 15 0.45 1.4 5.07 5.00
68 INT129856 Positive_regulation of TNFRSF11A 26 0.68 16.21 4.75 5.00
69 INT2144 Localization of COL7A1 36 0.74 20.92 4.67 5.00
70 INT141665 Gene_expression of AGRP 83 0.67 43.43 4.24 5.00
71 INT113282 Negative_regulation of TNFRSF11B 17 0.57 13.71 4.17 5.00
72 INT11370 Positive_regulation of LHB 15 0.28 5.45 4.01 5.00
73 INT5408 Localization of Alb 30 0.73 12.1 3.84 5.00
74 INT13302 Binding of PTAFR 20 0.48 7.03 3.7 5.00
75 INT116235 Negative_regulation of Transcription of Nos2 23 0.58 7.91 3.14 5.00
76 INT172551 Negative_regulation of INCENP 38 0.07 20.83 3.14 5.00
77 INT51680 Protein_catabolism of PTAFR 7 0.64 3.69 2.59 5.00
78 INT178888 Gene_expression of CHDH 41 0.65 38.66 2.51 5.00
79 INT147582 Negative_regulation of AIS 13 0.37 13.26 2.46 5.00
80 INT12033 Binding of PLOD1 15 0.48 8.04 2.3 5.00
81 INT19131 Localization of CYP27A1 14 0.80 8.19 2.15 5.00
82 INT111113 Binding of CYP19A1 15 0.36 9.17 2.12 5.00
83 INT7972 Positive_regulation of Gene_expression of PLOD1 15 0.42 5.73 1.96 5.00
84 INT130866 Positive_regulation of Gene_expression of TNFSF11 25 0.69 7.11 1.82 5.00
85 INT8960 Binding of SDHB 9 0.36 9.2 1.68 5.00
86 INT33496 Positive_regulation of Gene_expression of FSHR 14 0.46 6.05 1.66 5.00
87 INT123223 Binding of TNFAIP6 5 0.35 3.36 1.65 5.00
88 INT127889 Regulation of Gene_expression of CYP19A1 11 0.62 6.7 1.41 5.00
89 INT1651 Positive_regulation of Negative_regulation of PLOD1 4 0.46 0.49 1.33 5.00
90 INT123224 Gene_expression of TNFAIP6 12 0.70 7.13 1.21 5.00
91 INT108559 Gene_expression of Pol 46 0.45 30.07 1.14 5.00
92 INT209900 Negative_regulation of Gene_expression of TNFRSF11B 13 0.51 4.05 1.12 5.00
93 INT88948 Localization of Ace 9 0.69 9.18 1.11 5.00
94 INT67097 Gene_expression of MIB1 20 0.75 21.06 1.03 5.00
95 INT197721 Positive_regulation of ARMC9 36 0.35 20.08 1.03 5.00
96 INT189130 Regulation of AIS 11 0.39 7.64 0.99 5.00
97 INT62155 Positive_regulation of Gene_expression of DMD 17 0.67 6.17 0.82 5.00
98 INT269764 Positive_regulation of Localization of CYP27A1 4 0.38 2.45 0.8 5.00
99 INT84979 Regulation of CHDH 22 0.38 22.34 0.78 5.00
100 INT70362 Transcription of GH1 9 0.56 2.01 0.69 5.00
101 INT39865 Regulation of Positive_regulation of PLOD1 2 0.27 0.71 0.66 5.00
102 INT180578 Regulation of HEYL 3 0.06 3.15 0.49 5.00
103 INT84978 Positive_regulation of CHDH 21 0.50 21.97 0.48 5.00
104 INT241549 Negative_regulation of Gene_expression of AIS 5 0.37 3.72 0.48 5.00
105 INT200435 Binding of polymerase 6 0.16 5.56 0.47 5.00
106 INT127273 Gene_expression of AMH 24 0.78 9.53 0.47 5.00
107 INT187717 Regulation of Negative_regulation of CYP19A1 11 0.42 2.85 0.45 5.00
108 INT112054 Negative_regulation of Negative_regulation of DMD 12 0.44 5.02 0.45 5.00
109 INT68725 Regulation of Cyp11a1 6 0.19 2.62 0.44 5.00
110 INT158837 Binding of POLG 4 0.37 4.69 0.44 5.00
111 INT235457 Negative_regulation of Regulation of Nos2 3 0.42 1.55 0.39 5.00
112 INT95655 Negative_regulation of Gene_expression of MKI67 5 0.41 3.66 0.36 5.00
113 INT284907 Regulation of Transcription of AGRP 1 0.09 1.01 0.28 5.00
114 INT157135 Positive_regulation of MKI67 10 0.60 7.51 0.28 5.00
115 INT281403 Transcription of AGRP 4 0.47 1.61 0.27 5.00
116 INT127655 Localization of MKI67 6 0.73 3.72 0.26 5.00
117 INT138715 Gene_expression of POLG 12 0.66 6.97 0.23 5.00
118 INT175961 Protein_catabolism of polymerase 5 0.08 1.94 0.19 5.00
119 INT93885 Positive_regulation of Gene_expression of MKI67 8 0.60 4.4 0.18 5.00
120 INT250433 Regulation of Binding of AIS 2 0.39 1.56 0.17 5.00
121 INT277821 Positive_regulation of Negative_regulation of INCENP 2 0.03 0.89 0.12 5.00
122 INT229749 Regulation of Gene_expression of CHDH 7 0.27 5.94 0.12 5.00
123 INT331655 Negative_regulation of crf 1 0.19 5.85 0.11 5.00
124 INT186056 Binding of MKI67 6 0.48 4.44 0.1 5.00
125 INT297642 Regulation of crf 5 0.19 3.52 0.05 5.00
126 INT189923 Binding of Pol 5 0.20 2.09 0.04 5.00
127 INT268212 Negative_regulation of Gene_expression of Pol 3 0.25 2.13 0.04 5.00
128 INT310741 Gene_expression of POLG2 1 0.36 0.87 0.03 5.00
129 INT331654 Protein_catabolism of crf 1 0.29 1.43 0 5.00
130 INT310734 Negative_regulation of Phosphorylation of Pol 1 0.04 0.06 0 5.00
131 INT210818 Phosphorylation of HEYL 1 0.04 0.08 0 5.00
132 INT100663 Regulation of Gene_expression of MKI67 3 0.39 0.36 0 5.00
133 INT310733 Phosphorylation of Pol 1 0.09 0.06 0 5.00
134 INT187639 Localization of TNFAIP6 1 0.11 0.72 0 5.00
135 INT266162 Transcription of POLG 2 0.68 0.76 0 5.00
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