D:Primary Effusion Lymphoma

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Disease Term
Synonyms Effusion Lymphoma Primary, Effusion Lymphomas Primary, Lymphomas Primary Effusion, Primary Effusion Lymphomas
Documents 18
Hot Single Events 20
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Primary Effusion Lymphoma. They are ordered first by their relevance to Primary Effusion Lymphoma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT202509 Positive_regulation of Binding of Ltbr and Traf3 1 0.07 0.51 0 99.12
2 INT202504 Binding of Ltbr and Traf3 1 0.05 0.51 0 98.52
3 INT202506 Psmb8 Positive_regulation of Nfasc 1 0.01 0.59 0.06 76.48
4 INT295755 Fgf2 Regulation of MMP9 1 0.07 0.99 0.33 74.00
5 INT295717 VEGFA Regulation of MMP9 1 0.01 0.98 0.33 74.00
6 INT202505 Binding of Cd40lg and Positive_regulation of Positive_regulation of Nfasc 1 0.09 0.45 0.08 42.56
7 INT191432 Binding of COX10 and EDIL3 1 0.01 1.79 0.1 21.24
8 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74 5.00
9 INT295720 PTGER2 Regulation of MMP9 1 0.01 0.53 0.7 5.00
10 INT295705 Binding of IK and TNF 1 0.00 0.27 0.64 5.00
11 INT295724 CXCL12 Positive_regulation of MMP9 1 0.02 0.32 0.6 5.00
12 INT295721 CSF2 Positive_regulation of MMP9 1 0.06 0.32 0.6 5.00
13 INT295708 Binding of EGF and CCL2 1 0.01 0.79 0.49 5.00
14 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 0.31 1.77 0.48 5.00
15 INT295709 PTGER2 Regulation of VEGFA 1 0.01 1.61 0.41 5.00
16 INT295722 PTGER2 Positive_regulation of RAC1 1 0.02 2.14 0.32 5.00
17 INT295725 PTGER2 Positive_regulation of RAC2 1 0.05 1.92 0.32 5.00
18 INT295713 PTGER2 Positive_regulation of Regulation of CCL5 1 0.01 0.82 0.21 5.00
19 INT202508 Gpbar1 Positive_regulation of Positive_regulation of Nfasc 1 0.00 0.57 0.19 5.00
20 INT186860 MIR181A2HG Regulation of Cd86 1 0.02 1.05 0.07 5.00
21 INT186814 MIR181A2HG Regulation of ICAM1 1 0.01 1.05 0.07 5.00
22 INT295715 PTGER2 Regulation of Localization of FGF2 1 0.02 0.6 0.05 5.00
23 INT295719 VEGFA Regulation of Localization of PTGER2 1 0.02 0.6 0.05 5.00
24 INT295723 VEGFA Regulation of Localization of FGF2 1 0.07 0.6 0.05 5.00
25 INT295718 Binding of PTGER2 and Positive_regulation of Positive_regulation of SP1 1 0.02 0.58 0.04 5.00
26 INT295702 PTGER2 Positive_regulation of Racgap1 1 0.05 0.22 0 5.00
27 INT295710 PTGER2 Regulation of Positive_regulation of RAC1 1 0.01 1.62 0 5.00
28 INT295701 Positive_regulation of Binding of RAC1 and Racgap1 1 0.28 0.16 0 5.00
29 INT295704 Positive_regulation of Binding of RHOA and Racgap1 1 0.15 0.16 0 5.00
30 INT295706 PTGER2 Regulation of Regulation of RHOA 1 0.01 0.61 0 5.00
31 INT202507 Nfasc Positive_regulation of Gene_expression of Bcl2 1 0.10 0.7 0 5.00
32 INT295714 PTGER2 Positive_regulation of RHOA 1 0.01 0.34 0 5.00
33 INT295700 Binding of RAC1 and Racgap1 1 0.21 0.16 0 5.00
34 INT202503 Gtf3a Positive_regulation of Positive_regulation of Bcl2 1 0.02 0.35 0 5.00
35 INT300337 Gene_expression of MITF Negative_regulation of Gene_expression of TSC1 1 0.00 0.65 0 5.00
36 INT295703 Binding of RHOA and Racgap1 1 0.11 0.16 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Primary Effusion Lymphoma. They are ordered first by their pain relevance and then by number of times they were reported in Primary Effusion Lymphoma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT180163 Positive_regulation of Nfasc 49 0.40 31.96 9.41 99.84
2 INT82795 Binding of MYC 16 0.47 6.1 0.9 99.74
3 INT119700 Gene_expression of VDR 88 0.75 65.33 11.5 98.04
4 INT202490 Binding of Traf3 1 0.17 0.5 0 97.12
5 INT194913 Localization of Nfasc 17 0.36 9.91 3.76 94.40
6 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 93.12
7 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 93.12
8 INT11062 Positive_regulation of MME 24 0.63 14.37 5.26 91.60
9 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46 90.92
10 INT99767 Regulation of THBS1 18 0.42 11.51 1.03 90.88
11 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4 90.56
12 INT20418 Regulation of Gene_expression of MYC 6 0.60 4.4 1.29 90.56
13 INT20420 Gene_expression of MYC 99 0.75 49.32 14.36 90.56
14 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 90.56
15 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 90.52
16 INT68394 Gene_expression of KISS1 15 0.73 5.33 2.03 87.68
17 INT82798 Regulation of MYC 19 0.60 12.06 2.31 87.44
18 INT217807 Regulation of MITF 20 0.00 18.57 0.36 82.36
19 INT24672 Localization of FGF2 27 0.71 14.59 2.48 80.04
20 INT82817 Localization of FGF1 2 0.60 2.12 0.36 80.04
21 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 75.28
22 INT100005 Binding of MITF 7 0.47 6.93 0.44 75.12
23 INT89282 Regulation of MMP9 39 0.60 25.45 10.34 74.00
24 INT122195 Regulation of Localization of VEGFA 13 0.57 10.61 1.92 74.00
25 INT142907 Regulation of Localization of Fgf2 1 0.44 1.16 0.53 74.00
26 INT295690 Negative_regulation of Regulation of MMP9 1 0.11 0.99 0.33 74.00
27 INT252993 Negative_regulation of THBS1 8 0.55 6.93 0.59 73.56
28 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 72.32
29 INT68133 Localization of Fgf2 36 0.81 15.37 9.14 72.32
30 INT156097 Negative_regulation of Localization of VEGFA 70 0.58 34.96 4.17 72.32
31 INT99636 Negative_regulation of Localization of Fgf2 4 0.41 1.32 1.97 72.32
32 INT300351 Negative_regulation of S100A2 1 0.32 2.17 0 69.52
33 INT300360 Negative_regulation of PRG1 1 0.32 2.16 0 69.08
34 INT217168 Gene_expression of MIR21 30 0.55 30.86 0.62 67.28
35 INT217156 Positive_regulation of Gene_expression of MIR21 9 0.49 16.04 0.38 67.28
36 INT189096 Gene_expression of Psmb8 3 0.47 5.92 0.6 66.96
37 INT202487 Gene_expression of Ltbp1 1 0.07 0.55 0.07 66.96
38 INT194901 Regulation of Nfasc 8 0.21 5.76 1.15 58.16
39 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 57.68
40 INT129783 Positive_regulation of Gene_expression of KIT 16 0.50 18.12 0.58 57.68
41 INT300362 Positive_regulation of MIR203 1 0.15 1.37 0 47.84
42 INT300379 Positive_regulation of MIR205 1 0.11 1.36 0 47.36
43 INT300373 Regulation of C2orf40 1 0.02 1.34 0 44.40
44 INT300366 Regulation of MIR203 1 0.09 1.34 0 44.40
45 INT85965 Binding of Cd40lg 26 0.45 16.76 4.52 40.16
46 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 34.40
47 INT202489 Localization of Chuk 3 0.53 1.63 0.08 33.52
48 INT182170 Localization of RELB 14 0.52 9.78 4.44 30.96
49 INT202480 Localization of Nfkb2 1 0.56 0.37 0.08 30.56
50 INT217186 Gene_expression of MIR155 26 0.48 29.45 7.92 17.16
51 INT271570 Gene_expression of MIR1-1 21 0.65 11.49 1.03 17.16
52 INT268582 Gene_expression of MIR17 8 0.58 9.99 0.9 17.16
53 INT290988 Gene_expression of MIR93 3 0.58 1.59 0.07 17.16
54 INT82997 Negative_regulation of Binding of ras 3 0.05 3.78 0.94 14.96
55 INT81688 Binding of ras 32 0.41 30.13 4.02 13.12
56 INT202492 Phosphorylation of Nfasc 1 0.19 1.02 0.19 11.60
57 INT202472 Protein_catabolism of Nfasc 1 0.18 0.85 0.09 11.60
58 INT260877 Regulation of HEPACAM 6 0.03 4.28 0.04 11.44
59 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
60 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
61 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
62 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
63 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
64 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
65 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 5.00
66 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
67 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06 5.00
68 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 5.00
69 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 5.00
70 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
71 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
72 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 5.00
73 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 5.00
74 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 5.00
75 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
76 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 5.00
77 INT50672 Positive_regulation of CPOX 205 0.44 125.93 60.06 5.00
78 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 5.00
79 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 5.00
80 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74 5.00
81 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09 5.00
82 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 5.00
83 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9 5.00
84 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 5.00
85 INT52531 Gene_expression of Nfkb1 153 0.75 82.84 42.9 5.00
86 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
87 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 5.00
88 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 5.00
89 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 5.00
90 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 5.00
91 INT666 Gene_expression of Jun 124 0.78 54.61 33.67 5.00
92 INT84825 Gene_expression of CD36 121 0.78 43.73 33.23 5.00
93 INT64171 Regulation of CPOX 109 0.36 55.36 32.96 5.00
94 INT65698 Localization of CCL2 118 0.81 77.54 32.69 5.00
95 INT99610 Localization of MMP9 126 0.79 48.46 32.67 5.00
96 INT88318 Gene_expression of CXCR4 208 0.77 189.67 31.72 5.00
97 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
98 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 5.00
99 INT129207 Gene_expression of Cxcl1 114 0.75 68.54 30.82 5.00
100 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
101 INT165054 Gene_expression of MIR146A 45 0.58 82.87 28.82 5.00
102 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71 5.00
103 INT14690 Localization of CSF2 124 0.80 85.17 27.26 5.00
104 INT1765 Positive_regulation of Gene_expression of PTGER2 140 0.51 68.68 27 5.00
105 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42 5.00
106 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 5.00
107 INT1761 Positive_regulation of PTGER2 135 0.49 90.17 26.26 5.00
108 INT50490 Regulation of PTGS2 80 0.48 39.51 25.85 5.00
109 INT141612 Gene_expression of Ccr1 92 0.77 72.09 24.14 5.00
110 INT17275 Gene_expression of HIVEP1 267 0.75 232.07 24.06 5.00
111 INT63419 Gene_expression of PTGES 109 0.77 40.83 23.67 5.00
112 INT167856 Gene_expression of Nfasc 74 0.71 39.29 23.64 5.00
113 INT34487 Localization of MMP2 56 0.81 31.41 23.61 5.00
114 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05 5.00
115 INT71875 Localization of Nfkb1 92 0.78 48.13 22.94 5.00
116 INT34488 Negative_regulation of MMP2 85 0.59 41.98 21.72 5.00
117 INT14700 Regulation of IFNA1 111 0.45 66.16 21.52 5.00
118 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94 5.00
119 INT78901 Localization of CCL5 67 0.78 40.79 20.59 5.00
120 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 5.00
121 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 5.00
122 INT18311 Positive_regulation of CD8A 145 0.69 113.48 19.44 5.00
123 INT12725 Positive_regulation of Racgap1 66 0.68 32.74 19.29 5.00
124 INT101188 Gene_expression of Rela 81 0.56 23.43 19.15 5.00
125 INT14737 Gene_expression of FN1 117 0.78 78.74 18.99 5.00
126 INT10833 Regulation of Gene_expression of IL8 68 0.62 38.74 18.46 5.00
127 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 5.00
128 INT66857 Regulation of CCL2 39 0.53 28.55 18.35 5.00
129 INT35487 Localization of PTGER2 103 0.46 51.24 17.45 5.00
130 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7 5.00
131 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59 5.00
132 INT26501 Positive_regulation of Gene_expression of MMP2 51 0.67 39 15.16 5.00
133 INT69952 Positive_regulation of IK 45 0.32 16.08 14.59 5.00
134 INT1758 Positive_regulation of Gene_expression of TIMP1 62 0.69 31.72 13.98 5.00
135 INT50671 Regulation of Gene_expression of CPOX 45 0.54 30.99 13.83 5.00
136 INT108485 Gene_expression of CXCL12 61 0.75 49.34 13.79 5.00
137 INT133156 Binding of Cd40 77 0.48 45.92 13.77 5.00
138 INT27739 Positive_regulation of EGF 49 0.70 28.31 13.68 5.00
139 INT26545 Gene_expression of Hras1 173 0.78 79.54 13.21 5.00
140 INT27268 Localization of Gtf3a 71 0.21 56.93 12.51 5.00
141 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39 5.00
142 INT55687 Localization of TIMP1 47 0.74 30.24 12.31 5.00
143 INT69158 Localization of IL4 48 0.71 31.3 11.98 5.00
144 INT3699 Gene_expression of H2-Ab1 24 0.74 12.06 11.82 5.00
145 INT93715 Negative_regulation of MMP9 69 0.55 36.05 11.73 5.00
146 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63 5.00
147 INT1762 Negative_regulation of PTGER2 64 0.43 28.21 11.27 5.00
148 INT1763 Regulation of Gene_expression of PTGER2 43 0.36 23.98 10.95 5.00
149 INT34485 Negative_regulation of Localization of MMP2 17 0.50 9.96 10.49 5.00
150 INT78895 Regulation of CCL5 30 0.46 20.45 10.18 5.00
151 INT126031 Negative_regulation of Gene_expression of MMP9 40 0.57 22.71 9.79 5.00
152 INT2036 Localization of EGF 42 0.77 21.5 9.74 5.00
153 INT300347 Positive_regulation of Gene_expression of MIR146A 23 0.35 25.04 9.62 5.00
154 INT26502 Negative_regulation of Gene_expression of MMP2 39 0.58 21.45 9.42 5.00
155 INT14301 Binding of CSF2 82 0.48 67.95 8.98 5.00
156 INT187190 Positive_regulation of Localization of MMP9 27 0.68 8.1 8.93 5.00
157 INT66213 Localization of RELA 63 0.78 14.71 8.77 5.00
158 INT73558 Regulation of IK 23 0.23 12.02 8.73 5.00
159 INT34777 Localization of IGF1 82 0.80 42.68 8.62 5.00
160 INT102658 Negative_regulation of Gene_expression of CSF2 42 0.50 38.63 8.32 5.00
161 INT113987 Localization of IK 29 0.23 16.73 8.25 5.00
162 INT81777 Negative_regulation of Gene_expression of IK 22 0.08 11.55 8.09 5.00
163 INT21502 Gene_expression of Scn4a 22 0.78 4.47 7.97 5.00
164 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 5.00
165 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86 5.00
166 INT20705 Positive_regulation of Scn4a 18 0.68 4.34 7.85 5.00
167 INT64816 Transcription of Jun 31 0.69 16.01 7.64 5.00
168 INT91417 Positive_regulation of PTGES 36 0.68 18.45 7.64 5.00
169 INT82610 Positive_regulation of SRC 53 0.67 26.89 7.27 5.00
170 INT1123 Positive_regulation of CD79A 74 0.70 51.96 7.14 5.00
171 INT104979 Gene_expression of MITF 51 0.62 54.83 6.91 5.00
172 INT67568 Positive_regulation of Localization of MMP2 14 0.31 8.58 6.79 5.00
173 INT50255 Regulation of Cd4 39 0.49 29.73 6.77 5.00
174 INT35486 Regulation of PTGER2 39 0.36 19.03 6.75 5.00
175 INT1926 Positive_regulation of PLAT 54 0.66 31.42 6.49 5.00
176 INT141611 Positive_regulation of Gene_expression of Ccr1 25 0.69 20.32 6.42 5.00
177 INT83451 Positive_regulation of Gene_expression of CD40LG 26 0.60 22.81 6.25 5.00
178 INT194905 Positive_regulation of Gene_expression of Nfasc 16 0.10 11.87 6.19 5.00
179 INT14238 Positive_regulation of Cd69 19 0.60 17.75 6.07 5.00
180 INT108628 Regulation of MMP2 27 0.60 14.85 6.06 5.00
181 INT58393 Positive_regulation of Localization of PTGER2 37 0.25 16.8 6 5.00
182 INT92470 Negative_regulation of Gene_expression of CCL5 15 0.50 5.46 5.86 5.00
183 INT32155 Gene_expression of TNFRSF10B 36 0.67 30.32 5.74 5.00
184 INT85417 Positive_regulation of Gene_expression of IK 17 0.09 9.38 5.73 5.00
185 INT150853 Negative_regulation of Cxcl1 22 0.49 12.61 5.72 5.00
186 INT38671 Positive_regulation of KRT20 62 0.53 40.17 5.6 5.00
187 INT98685 Positive_regulation of Gene_expression of PTGES 28 0.68 9.46 5.55 5.00
188 INT99606 Negative_regulation of Localization of MMP9 23 0.57 7.15 5.47 5.00
189 INT69156 Localization of IL5 21 0.68 14.95 5.37 5.00
190 INT87211 Positive_regulation of Localization of Nfkb1 27 0.59 15.84 5.25 5.00
191 INT150856 Localization of Cxcl1 14 0.78 6.97 4.91 5.00
192 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9 5.00
193 INT128178 Positive_regulation of RHOA 59 0.68 9.3 4.7 5.00
194 INT101594 Positive_regulation of Cd40 36 0.69 16.14 4.56 5.00
195 INT107605 Gene_expression of MMP14 26 0.64 25.88 4.49 5.00
196 INT26404 Positive_regulation of ATM 15 0.49 10.94 4.39 5.00
197 INT1209 Binding of Kitl 14 0.37 6.72 4.3 5.00
198 INT58390 Negative_regulation of Localization of PTGER2 25 0.21 14.4 4.25 5.00
199 INT113282 Negative_regulation of TNFRSF11B 17 0.57 13.71 4.17 5.00
200 INT85677 Positive_regulation of Gpbar1 24 0.68 8.41 4.09 5.00
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